TreeWAS – Variant ID: rs4715166

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction	0.000	0.764	0.236
I27.2 Other secondary pulmonary hypertension	0.000	0.766	0.234
I69 Sequelae of cerebrovascular disease	0.000	0.768	0.232
I69.0 Sequelae of subarachnoid haemorrhage	0.000	0.773	0.227
I69.8 Sequelae of other and unspecified cerebrovascular diseases	0.000	0.804	0.196
I69.1 Sequelae of intracerebral haemorrhage	0.000	0.817	0.183
I69.3 Sequelae of cerebral infarction	0.000	0.823	0.177
I27 Other pulmonary heart diseases	0.000	0.825	0.175
I70.20 Atherosclerosis of arteries of extremities (without gangrene)	0.000	0.833	0.167
I70.2 Atherosclerosis of arteries of the extremities	0.000	0.840	0.160
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.000	0.843	0.157
I70 Atherosclerosis	0.000	0.844	0.156
I69.2 Sequelae of other nontraumatic intracranial haemorrhage	0.000	0.848	0.152
I70-I79 Diseases of arteries, arterioles and capillaries	0.000	0.849	0.151
S72.10 Pertrochanteric fracture (closed)	0.000	0.850	0.150
I74 Arterial embolism and thrombosis	0.000	0.853	0.147
I71 Aortic aneurysm and dissection	0.000	0.853	0.147
Chapter IX Diseases of the circulatory system	0.000	0.856	0.144
I60-I69 Cerebrovascular diseases	0.000	0.858	0.142
I05-I09 Chronic rheumatic heart diseases	0.000	0.862	0.138
I05 Rheumatic mitral valve diseases	0.000	0.864	0.136
I27.0 Primary pulmonary hypertension	0.000	0.867	0.133
I74.3 Embolism and thrombosis of arteries of the lower extremities	0.000	0.868	0.132
I74.5 Embolism and thrombosis of iliac artery	0.000	0.869	0.131
I70.0 Atherosclerosis of aorta	0.000	0.869	0.131
I71.2 Thoracic aortic aneurysm, without mention of rupture	0.000	0.870	0.130
I27.1 Kyphoscoliotic heart disease	0.000	0.874	0.126
I71.9 Aortic aneurysm of unspecified site, without mention of rupture	0.000	0.874	0.126
I05.9 Mitral valve disease, unspecified	0.000	0.874	0.126
I71.4 Abdominal aortic aneurysm, without mention of rupture	0.000	0.875	0.125
I05.2 Mitral stenosis with insufficiency	0.000	0.876	0.124
I74.0 Embolism and thrombosis of abdominal aorta	0.000	0.882	0.118
I71.0 Dissection of aorta [any part]	0.000	0.884	0.116
I05.0 Mitral stenosis	0.000	0.885	0.115
I70.21 Atherosclerosis of arteries of extremities (with gangrene)	0.000	0.885	0.115
I70.9 Generalised and unspecified atherosclerosis	0.000	0.886	0.114
I70.00 Atherosclerosis of aorta (without gangrene)	0.000	0.887	0.113
I00-I02 Acute rheumatic fever	0.000	0.887	0.113
I74.9 Embolism and thrombosis of unspecified artery	0.000	0.887	0.113
I74.2 Embolism and thrombosis of arteries of the upper extremities	0.000	0.888	0.112
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture	0.000	0.888	0.112
I28 Other diseases of pulmonary vessels	0.000	0.888	0.112
I74.1 Embolism and thrombosis of other and unspecified parts of aorta	0.000	0.889	0.111
I26 Pulmonary embolism	0.000	0.889	0.111
I68 Cerebrovascular disorders in diseases classified elsewhere	0.000	0.889	0.111
I74.4 Embolism and thrombosis of arteries of extremities, unspecified	0.000	0.889	0.111
I70.1 Atherosclerosis of renal artery	0.000	0.891	0.109
I71.1 Thoracic aortic aneurysm, ruptured	0.000	0.892	0.108
I67 Other cerebrovascular diseases	0.000	0.893	0.107
I27.8 Other specified pulmonary heart diseases	0.000	0.893	0.107
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.000	0.893	0.107
I71.8 Aortic aneurysm of unspecified site, ruptured	0.000	0.895	0.105
I71.5 Thoracoabdominal aortic aneurysm, ruptured	0.000	0.895	0.105
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction	0.000	0.898	0.102
I70.8 Atherosclerosis of other arteries	0.000	0.898	0.102
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction	0.000	0.898	0.102
I07 Rheumatic tricuspid valve diseases	0.000	0.899	0.100
I06 Rheumatic aortic valve diseases	0.000	0.901	0.098
I05.8 Other mitral valve diseases	0.000	0.904	0.096
I70.01 Atherosclerosis of aorta (with gangrene)	0.000	0.906	0.094
I67.9 Cerebrovascular disease, unspecified	0.000	0.906	0.094
I09 Other rheumatic heart diseases	0.000	0.907	0.093
I08 Multiple valve diseases	0.000	0.909	0.091
I65.0 Occlusion and stenosis of vertebral artery	0.000	0.909	0.091
I00 Rheumatic fever without mention of heart involvement	0.000	0.909	0.090
I68.0 Cerebral amyloid angiopathy	0.000	0.911	0.089
I05.1 Rheumatic mitral insufficiency	0.000	0.911	0.089
I70.90 Generalized and unspecified atherosclerosis (without gangrene)	0.000	0.915	0.084
I65.8 Occlusion and stenosis of other precerebral artery	0.000	0.916	0.084
I67.2 Cerebral atherosclerosis	0.000	0.916	0.084
I74.8 Embolism and thrombosis of other arteries	0.000	0.916	0.083
I70.91 Generalized and unspecified atherosclerosis (with gangrene)	0.000	0.918	0.082
I78 Diseases of capillaries	0.000	0.918	0.082
I66.9 Occlusion and stenosis of unspecified cerebral artery	0.000	0.918	0.082
I28.8 Other specified diseases of pulmonary vessels	0.000	0.918	0.081
I02 Rheumatic chorea	0.000	0.919	0.081
I01 Rheumatic fever with heart involvement	0.000	0.919	0.081
I28.0 Arteriovenous fistula of pulmonary vessels	0.000	0.919	0.081
I27.9 Pulmonary heart disease, unspecified	0.000	0.919	0.081
I26.0 Pulmonary embolism with mention of acute cor pulmonale	0.000	0.919	0.081
I28.1 Aneurysm of pulmonary artery	0.000	0.919	0.080
I71.3 Abdominal aortic aneurysm, ruptured	0.000	0.920	0.080
I68.8 Other cerebrovascular disorders in diseases classified elsewhere	0.000	0.920	0.080
I68.2 Cerebral arteritis in other diseases classified elsewhere	0.000	0.920	0.080
I68.1 Cerebral arteritis in infectious and parasitic diseases classified elsewhere	0.000	0.920	0.080
I08.2 Disorders of both aortic and tricuspid valves	0.000	0.920	0.080
I67.7 Cerebral arteritis, not elsewhere classified	0.000	0.921	0.079
H91.9 Hearing loss, unspecified	0.000	0.921	0.079
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.000	0.921	0.079
I67.1 Cerebral aneurysm, nonruptured	0.000	0.921	0.079
I70.11 Atherosclerosis of renal artery (with gangrene)	0.000	0.921	0.078
I28.9 Disease of pulmonary vessels, unspecified	0.000	0.922	0.078
I26.9 Pulmonary embolism without mention of acute cor pulmonale	0.000	0.922	0.078
I67.6 Nonpyogenic thrombosis of intracranial venous system	0.000	0.923	0.077
I67.5 Moyamoya disease	0.000	0.923	0.077
I67.3 Progressive vascular leukoencephalopathy	0.000	0.923	0.077
I79.1 Aortitis in diseases classified elsewhere	0.000	0.923	0.077
I79.0 Aneurysm of aorta in diseases classified elsewhere	0.000	0.923	0.077
I67.4 Hypertensive encephalopathy	0.000	0.923	0.077
I66.2 Occlusion and stenosis of posterior cerebral artery	0.000	0.924	0.076
I06.1 Rheumatic aortic insufficiency	0.000	0.924	0.076
I70.10 Atherosclerosis of renal artery (without gangrene)	0.000	0.924	0.075
I66.0 Occlusion and stenosis of middle cerebral artery	0.000	0.925	0.075
I08.1 Disorders of both mitral and tricuspid valves	0.000	0.926	0.074
I66.1 Occlusion and stenosis of anterior cerebral artery	0.000	0.926	0.073
I70.81 Atherosclerosis of other arteries (with gangrene)	0.000	0.927	0.073
I07.1 Tricuspid insufficiency	0.000	0.927	0.073
I65.9 Occlusion and stenosis of unspecified precerebral artery	0.000	0.927	0.073
I08.9 Multiple valve disease, unspecified	0.000	0.927	0.073
S72.1 Pertrochanteric fracture	0.000	0.927	0.073
I07.9 Tricuspid valve disease, unspecified	0.000	0.928	0.072
I07.8 Other tricuspid valve diseases	0.000	0.928	0.072
I07.2 Tricuspid stenosis with insufficiency	0.000	0.928	0.072
I07.0 Tricuspid stenosis	0.000	0.928	0.072
I79.2 Peripheral angiopathy in diseases classified elsewhere	0.000	0.928	0.072
I66.3 Occlusion and stenosis of cerebellar arteries	0.000	0.929	0.071
I06.8 Other rheumatic aortic valve diseases	0.000	0.929	0.071
I06.2 Rheumatic aortic stenosis with insufficiency	0.000	0.929	0.071
I66.4 Occlusion and stenosis of multiple and bilateral cerebral arteries	0.000	0.931	0.069
I62 Other nontraumatic intracranial haemorrhage	0.000	0.931	0.069
I65.3 Occlusion and stenosis of multiple and bilateral precerebral arteries	0.000	0.931	0.069
I06.0 Rheumatic aortic stenosis	0.000	0.931	0.069
I67.0 Dissection of cerebral arteries, nonruptured	0.000	0.932	0.068
I09.8 Other specified rheumatic heart diseases	0.000	0.933	0.067
I09.2 Chronic rheumatic pericarditis	0.000	0.933	0.067
I09.1 Rheumatic diseases of endocardium, valve unspecified	0.000	0.933	0.067
I09.0 Rheumatic myocarditis	0.000	0.933	0.067
I06.9 Rheumatic aortic valve disease, unspecified	0.000	0.933	0.066
I64 Stroke, not specified as haemorrhage or infarction	0.000	0.934	0.066
I08.8 Other multiple valve diseases	0.000	0.935	0.065
I78.9 Disease of capillaries, unspecified	0.000	0.935	0.065
I66.8 Occlusion and stenosis of other cerebral artery	0.000	0.936	0.064
I70.80 Atherosclerosis of other arteries (without gangrene)	0.000	0.937	0.063
I65.1 Occlusion and stenosis of basilar artery	0.000	0.939	0.061
I09.9 Rheumatic heart disease, unspecified	0.000	0.939	0.060
I78.8 Other diseases of capillaries	0.000	0.940	0.059
I73 Other peripheral vascular diseases	0.000	0.941	0.059
I01.9 Acute rheumatic heart disease, unspecified	0.000	0.941	0.058
I01.8 Other acute rheumatic heart disease	0.000	0.941	0.058
I01.2 Acute rheumatic myocarditis	0.000	0.941	0.058
I01.1 Acute rheumatic endocarditis	0.000	0.941	0.058
I01.0 Acute rheumatic pericarditis	0.000	0.941	0.058
I02.9 Rheumatic chorea without heart involvement	0.000	0.941	0.058
I02.0 Rheumatic chorea with heart involvement	0.000	0.941	0.058
I78.0 Hereditary haemorrhagic telangiectasia	0.000	0.942	0.058
I95-I99 Other and unspecified disorders of the circulatory system	0.000	0.942	0.058
I61 Intracerebral haemorrhage	0.000	0.943	0.057
S72.11 Pertrochanteric fracture (open)	0.000	0.948	0.052
I61.8 Other intracerebral haemorrhage	0.000	0.950	0.050
I73.1 Thromboangiitis obliterans [Buerger]	0.000	0.952	0.047
I73.8 Other specified peripheral vascular diseases	0.000	0.953	0.047
I99 Other and unspecified disorders of circulatory system	0.000	0.953	0.047
I62.1 Nontraumatic extradural haemorrhage	0.000	0.954	0.046
I61.6 Intracerebral haemorrhage, multiple localised	0.000	0.955	0.045
I62.0 Subdural haemorrhage (acute) (nontraumatic)	0.000	0.955	0.045
I60 Subarachnoid haemorrhage	0.000	0.957	0.043
I08.0 Disorders of both mitral and aortic valves	0.000	0.957	0.043
I67.8 Other specified cerebrovascular diseases	0.000	0.957	0.043
I61.0 Intracerebral haemorrhage in hemisphere, subcortical	0.000	0.959	0.041
I10-I15 Hypertensive diseases	0.000	0.959	0.041
I60.3 Subarachnoid haemorrhage from posterior communicating artery	0.000	0.959	0.041
I72 Other aneurysm	0.000	0.960	0.040
I97 Postprocedural disorders of circulatory system, not elsewhere classified	0.000	0.961	0.039
I61.4 Intracerebral haemorrhage in cerebellum	0.000	0.962	0.038
I61.9 Intracerebral haemorrhage, unspecified	0.000	0.962	0.038
I61.3 Intracerebral haemorrhage in brain stem	0.000	0.962	0.038
I98 Other disorders of circulatory system in diseases classified elsewhere	0.000	0.965	0.035
I11 Hypertensive heart disease	0.000	0.965	0.035
I62.9 Intracranial haemorrhage (nontraumatic), unspecified	0.000	0.966	0.034
H91 Other hearing loss	0.000	0.967	0.033
I11.0 Hypertensive heart disease with (congestive) heart failure	0.000	0.968	0.032
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation	0.000	0.968	0.031
I13 Hypertensive heart and renal disease	0.000	0.969	0.031
I60.5 Subarachnoid haemorrhage from vertebral artery	0.000	0.969	0.031
I60.4 Subarachnoid haemorrhage from basilar artery	0.000	0.969	0.031
I97.1 Other functional disturbances following cardiac surgery	0.000	0.969	0.031
I61.2 Intracerebral haemorrhage in hemisphere, unspecified	0.000	0.970	0.030
I72.1 Aneurysm of artery of upper extremity	0.000	0.970	0.030
I72.9 Aneurysm of unspecified site	0.000	0.970	0.030
I72.3 Aneurysm of iliac artery	0.000	0.970	0.030
I65.2 Occlusion and stenosis of carotid artery	0.000	0.970	0.030
I72.6 Aneurysm and dissection of vertebral artery	0.000	0.971	0.029
I72.5 Aneurysm and dissection of other precerebral arteries	0.000	0.971	0.029
I72.0 Aneurysm of carotid artery	0.000	0.971	0.029
I97.8 Other postprocedural disorders of circulatory system, not elsewhere classified	0.000	0.972	0.028
I60.8 Other subarachnoid haemorrhage	0.000	0.972	0.028
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified	0.000	0.972	0.027
I97.0 Postcardiotomy syndrome	0.000	0.972	0.027
I97.9 Postprocedural disorder of circulatory system, unspecified	0.000	0.973	0.027
H91.2 Sudden idiopathic hearing loss	0.000	0.973	0.027
I98.3 Oesophageal varices with bleeding in diseases classified elsewhere	0.000	0.974	0.026
Y84.0 Cardiac catheterisation	0.000	0.974	0.026
I61.1 Intracerebral haemorrhage in hemisphere, cortical	0.000	0.974	0.026
I98.8 Other specified disorders of circulatory system in diseases classified elsewhere	0.000	0.974	0.025
I98.1 Cardiovascular disorders in other infectious and parasitic diseases classified elsewhere	0.000	0.974	0.025
I98.0 Cardiovascular syphilis	0.000	0.974	0.025
H91.0 Ototoxic hearing loss	0.000	0.975	0.025
I60.6 Subarachnoid haemorrhage from other intracranial arteries	0.000	0.976	0.024
I13.9 Hypertensive heart and renal disease, unspecified	0.000	0.976	0.024
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure	0.000	0.976	0.024
I97.2 Postmastectomy lymphoedema syndrome	0.000	0.976	0.023
H91.3 Deaf mutism, not elsewhere classified	0.000	0.976	0.023
I61.5 Intracerebral haemorrhage, intraventricular	0.000	0.977	0.023
I72.2 Aneurysm of renal artery	0.000	0.977	0.023
H91.8 Other specified hearing loss	0.000	0.977	0.023
I13.0 Hypertensive heart and renal disease with (congestive) heart failure	0.000	0.977	0.023
Y84.6 Urinary catheterisation	0.000	0.978	0.022
I13.1 Hypertensive heart and renal disease with renal failure	0.000	0.978	0.022
I60.9 Subarachnoid haemorrhage, unspecified	0.000	0.978	0.022
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.000	0.979	0.021
I73.9 Peripheral vascular disease, unspecified	0.000	0.979	0.021
H91.1 Presbycusis	0.000	0.979	0.020
I11.9 Hypertensive heart disease without (congestive) heart failure	0.000	0.980	0.020
Y84.1 Kidney dialysis	0.000	0.980	0.020
I60.1 Subarachnoid haemorrhage from middle cerebral artery	0.000	0.980	0.020
I12 Hypertensive renal disease	0.000	0.981	0.019
Y84.9 Medical procedure, unspecified	0.000	0.982	0.018
I98.2 Oesophageal varices in diseases classified elsewhere	0.000	0.982	0.018
I15 Secondary hypertension	0.000	0.982	0.017
S72 Fracture of femur	0.000	0.983	0.017
I78.1 Naevus, nonneoplastic	0.000	0.984	0.016
R09.1 Pleurisy	0.016	0.984	0.000
I72.4 Aneurysm of artery of lower extremity	0.000	0.984	0.016
Y84.7 Blood-sampling	0.000	0.985	0.015
Y84.5 Insertion of gastric or duodenal sound	0.000	0.985	0.015
Q05.9 Spina bifida, unspecified	0.000	0.985	0.015
Y84.4 Aspiration of fluid	0.000	0.985	0.015
I63 Cerebral infarction	0.000	0.986	0.014
S72.9 Fracture of femur, part unspecified	0.000	0.986	0.014
I15.8 Other secondary hypertension	0.000	0.986	0.013
O42.0 Premature rupture of membranes, onset of labour within 24 hours	0.013	0.987	0.000
I15.2 Hypertension secondary to endocrine disorders	0.000	0.987	0.013
Y84.3 Shock therapy	0.000	0.987	0.013
O99.8 Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium	0.012	0.988	0.000
S72.7 Multiple fractures of femur	0.000	0.988	0.012
I60.2 Subarachnoid haemorrhage from anterior communicating artery	0.001	0.988	0.011
I15.0 Renovascular hypertension	0.000	0.988	0.011
S72.8 Fractures of other parts of femur	0.000	0.988	0.011
S72.90 Fracture of femur, part unspecified (closed)	0.000	0.989	0.011
I72.8 Aneurysm of other specified arteries	0.001	0.989	0.010
I12.0 Hypertensive renal disease with renal failure	0.000	0.989	0.011
S72.3 Fracture of shaft of femur	0.000	0.989	0.011
O03.4 Incomplete, without complication	0.011	0.989	0.000
S72.4 Fracture of lower end of femur	0.000	0.989	0.011
S72.2 Subtrochanteric fracture	0.000	0.989	0.011
I51.7 Cardiomegaly	0.000	0.989	0.011
I63.4 Cerebral infarction due to embolism of cerebral arteries	0.000	0.989	0.010
I63.8 Other cerebral infarction	0.000	0.990	0.010
I63.1 Cerebral infarction due to embolism of precerebral arteries	0.000	0.990	0.010
Z91.0 Personal history of allergy, other than to drugs and biological substances	0.000	0.990	0.010
S72.91 Fracture of femur, part unspecified (open)	0.000	0.990	0.010
S72.0 Fracture of neck of femur	0.000	0.990	0.010
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic	0.000	0.990	0.010
Q05 Spina bifida	0.000	0.991	0.009
S72.71 Multiple fractures of femur (open)	0.000	0.991	0.009
S72.70 Multiple fractures of femur (closed)	0.000	0.991	0.009
I08.3 Combined disorders of mitral, aortic and tricuspid valves	0.002	0.991	0.007
I77 Other disorders of arteries and arterioles	0.000	0.991	0.009
I15.1 Hypertension secondary to other renal disorders	0.000	0.991	0.008
I51 Complications and ill-defined descriptions of heart disease	0.000	0.991	0.009
I15.9 Seconday hypertension, unspecified	0.001	0.991	0.008
S72.81 Fractures of other parts of femur (open)	0.000	0.991	0.008
S72.31 Fracture of shaft of femur (open)	0.000	0.991	0.008
O20.8 Other haemorrhage in early pregnancy	0.008	0.991	0.000
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries	0.000	0.992	0.008
I63.0 Cerebral infarction due to thrombosis of precerebral arteries	0.000	0.992	0.008
I51.4 Myocarditis, unspecified	0.000	0.992	0.008
O68.1 Labour and delivery complicated by meconium in amniotic fluid	0.008	0.992	0.000
O03 Spontaneous abortion	0.008	0.992	0.000
S72.21 Subtrochanteric fracture (open)	0.000	0.992	0.008
T17.2 Foreign body in pharynx	0.000	0.992	0.008
I51.3 Intracardiac thrombosis, not elsewhere classified	0.000	0.992	0.008
S72.80 Fractures of other parts of femur (closed)	0.000	0.992	0.007
S72.41 Fracture of lower end of femur (open)	0.000	0.992	0.007
Q05.4 Unspecified spina bifida with hydrocephalus	0.000	0.992	0.007
T17 Foreign body in respiratory tract	0.000	0.993	0.007
S72.01 Fracture of neck of femur (open)	0.000	0.993	0.007
I51.1 Rupture of chordae tendineae, not elsewhere classified	0.000	0.993	0.007
I12.9 Hypertensive renal disease without renal failure	0.000	0.993	0.007
I77.2 Rupture of artery	0.000	0.993	0.007
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.007	0.993	0.000
S72.40 Fracture of lower end of femur (closed)	0.000	0.993	0.007
T17.5 Foreign body in bronchus	0.000	0.993	0.007
I51.0 Cardiac septal defect, acquired	0.000	0.993	0.007
T17.9 Foreign body in respiratory tract, part unspecified	0.000	0.993	0.007
T17.8 Foreign body in other and multiple parts of respiratory tract	0.000	0.993	0.007
Q05.8 Sacral spina bifida without hydrocephalus	0.000	0.993	0.007
Q05.6 Thoracic spina bifida without hydrocephalus	0.000	0.993	0.007
Q05.5 Cervical spina bifida without hydrocephalus	0.000	0.993	0.007
Q05.3 Sacral spina bifida with hydrocephalus	0.000	0.993	0.007
Q05.2 Lumbar spina bifida with hydrocephalus	0.000	0.993	0.007
Q05.1 Thoracic spina bifida with hydrocephalus	0.000	0.993	0.007
Q05.0 Cervical spina bifida with hydrocephalus	0.000	0.993	0.007
O20.9 Haemorrhage in early pregnancy, unspecified	0.007	0.993	0.000
O20 Haemorrhage in early pregnancy	0.007	0.993	0.000
O03.3 Incomplete, with other and unspecified complications	0.007	0.993	0.000
O99.2 Endocrine, nutritional and metabolic diseases complicating pregnancy, childbirth and the puerperium	0.007	0.993	0.000
S72.30 Fracture of shaft of femur (closed)	0.000	0.993	0.007
I77.5 Necrosis of artery	0.000	0.993	0.007
I77.4 Coeliac artery compression syndrome	0.000	0.993	0.007
O99.0 Anaemia complicating pregnancy, childbirth and the puerperium	0.007	0.993	0.000
I51.8 Other ill-defined heart diseases	0.000	0.993	0.007
I51.5 Myocardial degeneration	0.000	0.993	0.007
I51.2 Rupture of papillary muscle, not elsewhere classified	0.000	0.993	0.006
Q05.7 Lumbar spina bifida without hydrocephalus	0.000	0.993	0.006
I63.3 Cerebral infarction due to thrombosis of cerebral arteries	0.000	0.993	0.006
I77.3 Arterial fibromuscular dysplasia	0.000	0.994	0.006
O03.1 Incomplete, complicated by delayed or excessive haemorrhage	0.006	0.994	0.000
O03.9 Complete or unspecified, without complication	0.006	0.994	0.000
O03.6 Complete or unspecified, complicated by delayed or excessive haemorrhage	0.006	0.994	0.000
S72.20 Subtrochanteric fracture (closed)	0.000	0.994	0.006
C71 Malignant neoplasm of brain	0.006	0.994	0.000
C71.1 Frontal lobe	0.006	0.994	0.000
C71.3 Parietal lobe	0.006	0.994	0.000
O03.7 Complete or unspecified, complicated by embolism	0.006	0.994	0.000
O03.5 Complete or unspecified, complicated by genital tract and pelvic infection	0.006	0.994	0.000
O03.2 Incomplete, complicated by embolism	0.006	0.994	0.000
O03.0 Incomplete, complicated by genital tract and pelvic infection	0.006	0.994	0.000
O42 Premature rupture of membranes	0.006	0.994	0.000
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency	0.000	0.994	0.006
O03.8 Complete or unspecified, with other and unspecified complications	0.006	0.994	0.000
N80.3 Endometriosis of pelvic peritoneum	0.006	0.994	0.000
I51.9 Heart disease, unspecified	0.000	0.994	0.006
C71.9 Brain, unspecified	0.006	0.994	0.000
I20-I25 Ischaemic heart diseases	0.000	0.994	0.006
T17.4 Foreign body in trachea	0.000	0.994	0.006
T17.1 Foreign body in nostril	0.000	0.994	0.006
T17.0 Foreign body in nasal sinus	0.000	0.994	0.006
Q54.9 Hypospadias, unspecified	0.006	0.994	0.000
C71.2 Temporal lobe	0.005	0.995	0.000
O99.3 Mental disorders and diseases of the nervous system complicating pregnancy, childbirth and the puerperium	0.005	0.995	0.000
C71.0 Cerebrum, except lobes and ventricles	0.005	0.995	0.000
O42.9 Premature rupture of membranes, unspecified	0.005	0.995	0.000
C71.6 Cerebellum	0.005	0.995	0.000
Q54.1 Hypospadias, penile	0.005	0.995	0.000
O94-O99 Other obstetric conditions, not elsewhere classified	0.005	0.995	0.000
I51.6 Cardiovascular disease, unspecified	0.000	0.995	0.005
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries	0.000	0.995	0.005
O99.4 Diseases of the circulatory system complicating pregnancy, childbirth and the puerperium	0.005	0.995	0.000
I77.8 Other specified disorders of arteries and arterioles	0.000	0.995	0.005
T17.3 Foreign body in larynx	0.000	0.995	0.005
C71.5 Cerebral ventricle	0.005	0.995	0.000
Q54 Hypospadias	0.005	0.995	0.000
S72.00 Fracture of neck of femur (closed)	0.000	0.995	0.005
S49.9 Unspecified injury of shoulder and upper arm	0.000	0.995	0.005
O99.7 Diseases of the skin and subcutaneous tissue complicating pregnancy, childbirth and the puerperium	0.005	0.995	0.000
I23 Certain current complications following acute myocardial infarction	0.000	0.995	0.005
L57.8 Other skin changes due to chronic exposure to nonionising radiation	0.005	0.995	0.000
I73.0 Raynaud's syndrome	0.000	0.995	0.005
O42.2 Premature rupture of membranes, labour delayed by therapy	0.004	0.995	0.000
D37.7 Other digestive organs	0.004	0.995	0.000
O98 Maternal infectious and parasitic diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.004	0.996	0.000
O20.0 Threatened abortion	0.004	0.996	0.000
D86.0 Sarcoidosis of lung	0.004	0.996	0.000
O99.1 Other diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism complicating pregnancy, childbirth and the puerperium	0.004	0.996	0.000
C51.9 Vulva, unspecified	0.004	0.996	0.000
O99.6 Diseases of the digestive system complicating pregnancy, childbirth and the puerperium	0.004	0.996	0.000
C71.8 Overlapping lesion of brain	0.004	0.996	0.000
Q54.0 Hypospadias, balanic	0.004	0.996	0.000
C71.7 Brain stem	0.004	0.996	0.000
O97 Death from sequelae of direct obstetric causes	0.004	0.996	0.000
O96 Death from any obstetric cause occurring more than 42 days but less than one year after delivery	0.004	0.996	0.000
O95 Obstetric death of unspecified cause	0.004	0.996	0.000
O94 Sequelae of complication of pregnancy, childbirth and the puerperium	0.004	0.996	0.000
Q54.8 Other hypospadias	0.004	0.996	0.000
O98.8 Other maternal infectious and parasitic diseases complicating pregnancy, childbirth and the puerperium	0.004	0.996	0.000
D51 Vitamin B12 deficiency anaemia	0.000	0.996	0.004
O41.0 Oligohydramnios	0.004	0.996	0.000
C71.4 Occipital lobe	0.004	0.996	0.000
Q00-Q07 Congenital malformations of the nervous system	0.000	0.996	0.004
Q54.4 Congenital chordee	0.004	0.996	0.000
Q54.3 Hypospadias, perineal	0.004	0.996	0.000
Q54.2 Hypospadias, penoscrotal	0.004	0.996	0.000
O47.1 False labour at or after 37 completed weeks of gestation	0.004	0.996	0.000
I77.0 Arteriovenous fistula, acquired	0.001	0.996	0.003
I23.8 Other current complications following acute myocardial infarction	0.000	0.996	0.004
I77.6 Arteritis, unspecified	0.000	0.996	0.004
R54 Senility	0.000	0.996	0.004
I77.9 Disorder of arteries and arterioles, unspecified	0.000	0.996	0.004
I95 Hypotension	0.000	0.996	0.004
D51.3 Other dietary vitamin B12 deficiency anaemia	0.000	0.996	0.004
D86.9 Sarcoidosis, unspecified	0.004	0.996	0.000
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction	0.000	0.996	0.003
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction	0.000	0.996	0.003
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction	0.000	0.996	0.003
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction	0.000	0.996	0.003
I23.2 Ventricular septal defect as current complication following acute myocardial infarction	0.000	0.996	0.003
I23.1 Atrial septal defect as current complication following acute myocardial infarction	0.000	0.996	0.003
I23.0 Haemopericardium as current complication following acute myocardial infarction	0.000	0.996	0.003
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.000	0.996	0.004
Z82.3 Family history of stroke	0.000	0.996	0.004
S22.30 Fracture of rib (closed)	0.000	0.996	0.004
I20.0 Unstable angina	0.000	0.996	0.004
D86 Sarcoidosis	0.003	0.996	0.000
O68.0 Labour and delivery complicated by foetal heart rate anomaly	0.003	0.997	0.000
O41 Other disorders of amniotic fluid and membranes	0.003	0.997	0.000
O20-O29 Other maternal disorders predominantly related to pregnancy	0.003	0.997	0.000
O98.9 Unspecified maternal infectious or parasitic disease complicating pregnancy, childbirth and the puerperium	0.003	0.997	0.000
O98.7 Human immunodeficiency [HIV] disease complicating pregnancy, childbirth and the puerperium	0.003	0.997	0.000
O98.6 Protozoal diseases complicating pregnancy, childbirth and the puerperium	0.003	0.997	0.000
O98.4 Viral hepatitis complicating pregnancy, childbirth and the puerperium	0.003	0.997	0.000
O98.2 Gonorrhoea complicating pregnancy, childbirth and the puerperium	0.003	0.997	0.000
O98.1 Syphilis complicating pregnancy, childbirth and the puerperium	0.003	0.997	0.000
O98.0 Tuberculosis complicating pregnancy, childbirth and the puerperium	0.003	0.997	0.000
I20 Angina pectoris	0.000	0.997	0.003
H43.1 Vitreous haemorrhage	0.000	0.997	0.003
O98.5 Other viral diseases complicating pregnancy, childbirth and the puerperium	0.003	0.997	0.000
O98.3 Other infections with a predominantly sexual mode of transmission complicating pregnancy, childbirth and the puerperium	0.003	0.997	0.000
J84.1 Other interstitial pulmonary diseases with fibrosis	0.003	0.997	0.000
S22.3 Fracture of rib	0.000	0.997	0.003
Z47.0 Follow-up care involving removal of fracture plate and other internal fixation device	0.000	0.997	0.003
O47 False labour	0.003	0.997	0.000
O24.9 Diabetes mellitus in pregnancy, unspecified	0.003	0.997	0.000
I63.9 Cerebral infarction, unspecified	0.000	0.997	0.003
O99.5 Diseases of the respiratory system complicating pregnancy, childbirth and the puerperium	0.003	0.997	0.000
I25.5 Ischaemic cardiomyopathy	0.000	0.997	0.003
O68 Labour and delivery complicated by foetal stress [distress]	0.003	0.997	0.000
S22 Fracture of rib(s), sternum and thoracic spine	0.000	0.997	0.003
O00-O08 Pregnancy with abortive outcome	0.003	0.997	0.000
N36.8 Other specified disorders of urethra	0.003	0.997	0.000
D51.9 Vitamin B12 deficiency anaemia, unspecified	0.000	0.997	0.003
S22.20 Fracture of sternum (closed)	0.000	0.997	0.003
Q03 Congenital hydrocephalus	0.000	0.997	0.003
D51.8 Other vitamin B12 deficiency anaemias	0.000	0.997	0.003
O96.9 Death from unspecified obstetric cause	0.003	0.997	0.000
O96.1 Death from indirect obstetric cause	0.003	0.997	0.000
O96.0 Death from direct obstetric cause	0.003	0.997	0.000
O97.9 Death from sequelae of obstetric cause, unspecified	0.003	0.997	0.000
O97.1 Death from sequelae of indirect obstetric cause	0.003	0.997	0.000
O97.0 Death from sequelae of direct obstetric cause	0.003	0.997	0.000
S22.2 Fracture of sternum	0.000	0.997	0.003
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems	0.003	0.997	0.000
S22.40 Multiple fractures of ribs (closed)	0.000	0.997	0.003
S22.4 Multiple fractures of ribs	0.000	0.997	0.003
D51.2 Transcobalamin II deficiency	0.000	0.997	0.003
D51.1 Vitamin B12 deficiency anaemia due to selective vitamin B12 malabsorption with proteinuria	0.000	0.997	0.003
I25.8 Other forms of chronic ischaemic heart disease	0.000	0.997	0.003
Q04 Other congenital malformations of brain	0.000	0.997	0.003
O24 Diabetes mellitus in pregnancy	0.003	0.997	0.000
D86.1 Sarcoidosis of lymph nodes	0.003	0.997	0.000
Q06 Other congenital malformations of spinal cord	0.000	0.997	0.003
Q01 Encephalocele	0.000	0.997	0.003
Q00 Anencephaly and similar malformations	0.000	0.997	0.003
Q02 Microcephaly	0.000	0.997	0.003
O28 Abnormal findings on antenatal screening of mother	0.003	0.997	0.000
C69.3 Choroid	0.000	0.997	0.003
Y84.8 Other medical procedures	0.000	0.997	0.003
I95.0 Idiopathic hypotension	0.000	0.997	0.003
Z42.0 Follow-up care involving plastic surgery of head and neck	0.003	0.997	0.000
G93.2 Benign intracranial hypertension	0.000	0.997	0.003
O41.1 Infection of amniotic sac and membranes	0.003	0.997	0.000
Y84.2 Radiological procedure and radiotherapy	0.000	0.997	0.003
G93.1 Anoxic brain damage, not elsewhere classified	0.000	0.997	0.003
I25 Chronic ischaemic heart disease	0.000	0.997	0.003
Chapter XV Pregnancy, childbirth and the puerperium	0.003	0.997	0.000
O33 Maternal care for known or suspected disproportion	0.003	0.997	0.000
M77.9 Enthesopathy, unspecified	0.003	0.997	0.000
O43.1 Malformation of placenta	0.003	0.997	0.000
M77.97 Enthesopathy, unspecified (Ankle and foot)	0.003	0.997	0.000
S22.0 Fracture of thoracic vertebra	0.000	0.997	0.003
G93 Other disorders of brain	0.000	0.997	0.003
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes	0.003	0.997	0.000
I25.0 Atherosclerotic cardiovascular disease, so described	0.000	0.997	0.003
O34.3 Maternal care for cervical incompetence	0.003	0.997	0.000
O29 Complications of anaesthesia during pregnancy	0.003	0.997	0.000
O25 Malnutrition in pregnancy	0.003	0.997	0.000
M77.96 Enthesopathy, unspecified (Lower leg)	0.003	0.997	0.000
O28.1 Abnormal biochemical finding on antenatal screening of mother	0.003	0.997	0.000
C51 Malignant neoplasm of vulva	0.003	0.997	0.000
O41.9 Disorder of amniotic fluid and membranes, unspecified	0.003	0.997	0.000
O45 Premature separation of placenta [abruptio placentae]	0.003	0.997	0.000
O34 Maternal care for known or suspected abnormality of pelvic organs	0.003	0.997	0.000
Q07 Other congenital malformations of nervous system	0.000	0.997	0.003
M23.20 Derangement of meniscus due to old tear or injury (Multiple sites)	0.000	0.997	0.003
O33.5 Maternal care for disproportion due to unusually large foetus	0.003	0.997	0.000
S22.1 Multiple fractures of thoracic spine	0.000	0.997	0.003
O23 Infections of genito-urinary tract in pregnancy	0.003	0.997	0.000
M77.95 Enthesopathy, unspecified (Pelvic region and thigh)	0.003	0.997	0.000
M77.91 Enthesopathy, unspecified (Shoulder region)	0.003	0.997	0.000
S22.31 Fracture of rib (open)	0.000	0.997	0.002
G93.5 Compression of brain	0.000	0.997	0.003
O28.3 Abnormal ultrasonic finding on antenatal screening of mother	0.003	0.997	0.000
S22.5 Flail chest	0.000	0.997	0.003
O43 Placental disorders	0.003	0.997	0.000
G93.6 Cerebral oedema	0.000	0.997	0.003
O24.0 Pre-existing diabetes mellitus, insulin-dependent	0.003	0.997	0.000
O06 Unspecified abortion	0.003	0.997	0.000
O36.0 Maternal care for rhesus isoimmunisation	0.003	0.997	0.000
G93.0 Cerebral cysts	0.000	0.997	0.003
Q03.0 Malformations of aqueduct of Sylvius	0.000	0.997	0.002
Q04.6 Congenital cerebral cysts	0.000	0.997	0.002
S22.9 Fracture of bony thorax, part unspecified	0.000	0.997	0.002
S22.8 Fracture of other parts of bony thorax	0.000	0.997	0.002
O08 Complications following abortion and ectopic and molar pregnancy	0.002	0.997	0.000
O07 Failed attempted abortion	0.002	0.997	0.000
O05 Other abortion	0.002	0.997	0.000
C51.0 Labium majus	0.002	0.997	0.000
O41.8 Other specified disorders of amniotic fluid and membranes	0.002	0.997	0.000
D86.3 Sarcoidosis of skin	0.002	0.997	0.000
O28.9 Abnormal finding on antenatal screening of mother, unspecified	0.002	0.997	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations