TreeWAS – Variant ID: rs4725982

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
H40.1 Primary open-angle glaucoma	0.201	0.799	0.000
H40 Glaucoma	0.133	0.867	0.000
H40.9 Glaucoma, unspecified	0.126	0.874	0.000
H40.0 Glaucoma suspect	0.108	0.892	0.000
R00.2 Palpitations	0.000	0.899	0.101
H40.6 Glaucoma secondary to drugs	0.095	0.904	0.000
H40.5 Glaucoma secondary to other eye disorders	0.095	0.905	0.000
H40.4 Glaucoma secondary to eye inflammation	0.093	0.907	0.000
H40.3 Glaucoma secondary to eye trauma	0.093	0.907	0.000
R00 Abnormalities of heart beat	0.000	0.909	0.091
R00.0 Tachycardia, unspecified	0.000	0.912	0.088
R00.8 Other and unspecified abnormalities of heart beat	0.000	0.913	0.087
H40.8 Other glaucoma	0.083	0.917	0.000
H40-H42 Glaucoma	0.059	0.941	0.000
H42 Glaucoma in diseases classified elsewhere	0.042	0.957	0.000
H42.8 Glaucoma in other diseases classified elsewhere	0.030	0.969	0.000
H42.0 Glaucoma in endocrine, nutritional and metabolic diseases	0.030	0.969	0.000
R00.1 Bradycardia, unspecified	0.000	0.981	0.019
K50 Crohn's disease [regional enteritis]	0.018	0.982	0.000
K50.0 Crohn's disease of small intestine	0.018	0.982	0.000
K50.9 Crohn's disease, unspecified	0.018	0.982	0.000
K50.1 Crohn's disease of large intestine	0.017	0.983	0.000
H26.9 Cataract, unspecified	0.017	0.983	0.000
H40.2 Primary angle-closure glaucoma	0.014	0.986	0.000
K61.0 Anal abscess	0.013	0.987	0.000
K50.8 Other Crohn's disease	0.012	0.988	0.000
R55 Syncope and collapse	0.000	0.990	0.010
K50-K52 Noninfective enteritis and colitis	0.010	0.990	0.000
H26.2 Complicated cataract	0.010	0.990	0.000
K51 Ulcerative colitis	0.009	0.991	0.000
H26 Other cataract	0.009	0.991	0.000
K51.0 Ulcerative (chronic) enterocolitis	0.009	0.991	0.000
K51.3 Ulcerative (chronic) rectosigmoiditis	0.008	0.992	0.000
K51.4 Pseudopolyposis of colon	0.008	0.992	0.000
K51.5 Mucosal proctocolitis	0.007	0.992	0.000
K51.2 Ulcerative (chronic) proctitis	0.007	0.993	0.000
K51.1 Ulcerative (chronic) ileocolitis	0.007	0.993	0.000
K61 Abscess of anal and rectal regions	0.007	0.993	0.000
H26.3 Drug-induced cataract	0.007	0.993	0.000
K51.9 Ulcerative colitis, unspecified	0.006	0.994	0.000
H25-H28 Disorders of lens	0.006	0.994	0.000
K61.1 Rectal abscess	0.006	0.994	0.000
H26.1 Traumatic cataract	0.006	0.994	0.000
Chapter VII Diseases of the eye and adnexa	0.006	0.994	0.000
K61.4 Intrasphincteric abscess	0.005	0.995	0.000
K61.2 Anorectal abscess	0.005	0.995	0.000
H26.0 Infantile, juvenile and presenile cataract	0.005	0.995	0.000
K61.3 Ischiorectal abscess	0.005	0.995	0.000
S90.3 Contusion of other and unspecified parts of foot	0.005	0.995	0.000
M19.07 Primary arthrosis of other joints (Ankle and foot)	0.000	0.995	0.005
H46-H48 Disorders of optic nerve and visual pathways	0.005	0.995	0.000
H28 Cataract and other disorders of lens in diseases classified elsewhere	0.005	0.995	0.000
S90 Superficial injury of ankle and foot	0.005	0.995	0.000
C64 Malignant neoplasm of kidney, except renal pelvis	0.005	0.995	0.000
H27 Other disorders of lens	0.005	0.995	0.000
H26.8 Other specified cataract	0.005	0.995	0.000
H10-H13 Disorders of conjunctiva	0.005	0.995	0.000
E04.2 Non-toxic multinodular goitre	0.000	0.995	0.005
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.004	0.996	0.000
H27.0 Aphakia	0.004	0.996	0.000
N94.1 Dyspareunia	0.000	0.996	0.004
K51.8 Other ulcerative colitis	0.004	0.996	0.000
S90.0 Contusion of ankle	0.004	0.996	0.000
H43-H45 Disorders of vitreous body and globe	0.004	0.996	0.000
H46 Optic neuritis	0.004	0.996	0.000
H20 Iridocyclitis	0.004	0.996	0.000
H55-H59 Other disorders of eye and adnexa	0.004	0.996	0.000
S90-S99 Injuries to the ankle and foot	0.004	0.996	0.000
S99.9 Unspecified injury of ankle and foot	0.004	0.996	0.000
H13 Disorders of conjunctiva in diseases classified elsewhere	0.004	0.996	0.000
L43.9 Lichen planus, unspecified	0.000	0.996	0.004
S99 Other and unspecified injuries of ankle and foot	0.004	0.996	0.000
H47 Other disorders of optic [2nd] nerve and visual pathways	0.004	0.996	0.000
O48 Prolonged pregnancy	0.004	0.996	0.000
S91.3 Open wound of other parts of foot	0.004	0.996	0.000
H11 Other disorders of conjunctiva	0.004	0.996	0.000
H20.9 Iridocyclitis, unspecified	0.004	0.996	0.000
S90.8 Other superficial injuries of ankle and foot	0.004	0.996	0.000
H48 Disorders of optic [2nd] nerve and visual pathways in diseases classified elsewhere	0.004	0.996	0.000
H25.8 Other senile cataract	0.004	0.996	0.000
H26.4 After-cataract	0.004	0.996	0.000
H28.8 Other disorders of lens in diseases classified elsewhere	0.004	0.996	0.000
H28.2 Cataract in other diseases classified elsewhere	0.004	0.996	0.000
H28.1 Cataract in other endocrine, nutritional and metabolic diseases	0.004	0.996	0.000
H28.0 Diabetic cataract	0.004	0.996	0.000
S90.9 Superficial injury of ankle and foot, unspecified	0.004	0.996	0.000
S90.7 Multiple superficial injuries of ankle and foot	0.004	0.996	0.000
S90.2 Contusion of toe(s) with damage to nail	0.004	0.996	0.000
S90.1 Contusion of toe(s) without damage to nail	0.004	0.996	0.000
N62 Hypertrophy of breast	0.004	0.996	0.000
C78.5 Secondary malignant neoplasm of large intestine and rectum	0.004	0.996	0.000
H11.9 Disorder of conjunctiva, unspecified	0.004	0.996	0.000
H27.9 Disorder of lens, unspecified	0.003	0.996	0.000
H16 Keratitis	0.004	0.996	0.000
H59 Postprocedural disorders of eye and adnexa, not elsewhere classified	0.004	0.996	0.000
S92 Fracture of foot, except ankle	0.004	0.996	0.000
Y88.3 Sequelae of surgical and medical procedures as the cause of abnormal reaction of the patient or of later complication, without mention of misadventure at the time of the procedure	0.004	0.996	0.000
G93.3 Postviral fatigue syndrome	0.000	0.996	0.004
H21 Other disorders of iris and ciliary body	0.004	0.996	0.000
H59.8 Other postprocedural disorders of eye and adnexa	0.003	0.996	0.000
S91 Open wound of ankle and foot	0.003	0.996	0.000
H22 Disorders of iris and ciliary body in diseases classified elsewhere	0.003	0.997	0.000
C65 Malignant neoplasm of renal pelvis	0.003	0.997	0.000
I24.0 Coronary thrombosis not resulting in myocardial infarction	0.000	0.997	0.003
H20.1 Chronic iridocyclitis	0.003	0.997	0.000
H13.3 Ocular pemphigoid	0.003	0.997	0.000
H27.1 Dislocation of lens	0.003	0.997	0.000
I86.4 Gastric varices	0.003	0.997	0.000
G93.9 Disorder of brain, unspecified	0.000	0.997	0.003
H20.0 Acute and subacute iridocyclitis	0.003	0.997	0.000
H47.2 Optic atrophy	0.003	0.997	0.000
S96 Injury of muscle and tendon at ankle and foot level	0.003	0.997	0.000
H13.1 Conjunctivitis in infectious and parasitic diseases classified elsewhere	0.003	0.997	0.000
H15 Disorders of sclera	0.003	0.997	0.000
H11.3 Conjunctival haemorrhage	0.003	0.997	0.000
H45 Disorders of vitreous body and globe in diseases classified elsewhere	0.003	0.997	0.000
H11.2 Conjunctival scars	0.003	0.997	0.000
H21.0 Hyphaema	0.003	0.997	0.000
H19 Disorders of sclera and cornea in diseases classified elsewhere	0.003	0.997	0.000
K52 Other non-infective gastro-enteritis and colitis	0.003	0.997	0.000
H47.3 Other disorders of optic disk	0.003	0.997	0.000
I50.1 Left ventricular failure	0.000	0.997	0.003
K52.3 Indeterminate colitis	0.003	0.997	0.000
H11.8 Other specified disorders of conjunctiva	0.003	0.997	0.000
H20.2 Lens-induced iridocyclitis	0.003	0.997	0.000
S99.8 Other specified injuries of ankle and foot	0.003	0.997	0.000
S97 Crushing injury of ankle and foot	0.003	0.997	0.000
H44 Disorders of globe	0.003	0.997	0.000
S98 Traumatic amputation of ankle and foot	0.003	0.997	0.000
S95 Injury of blood vessels at ankle and foot level	0.003	0.997	0.000
S94 Injury of nerves at ankle and foot level	0.003	0.997	0.000
H47.0 Disorders of optic nerve, not elsewhere classified	0.003	0.997	0.000
H13.8 Other disorders of conjunctiva in diseases classified elsewhere	0.003	0.997	0.000
H13.2 Conjunctivitis in other diseases classified elsewhere	0.003	0.997	0.000
H13.0 Filarial infection of conjunctiva	0.003	0.997	0.000
H16.8 Other keratitis	0.003	0.997	0.000
H16.4 Corneal neovascularisation	0.003	0.997	0.000
S99.7 Multiple injuries of ankle and foot	0.003	0.997	0.000
Y52.5 Other antihypertensive drugs, not elsewhere classified	0.000	0.997	0.003
C64-C68 Malignant neoplasms of urinary tract	0.003	0.997	0.000
H16.2 Keratoconjunctivitis	0.003	0.997	0.000
H47.7 Disorder of visual pathways, unspecified	0.003	0.997	0.000
H47.6 Disorders of visual cortex	0.003	0.997	0.000
H47.5 Disorders of other visual pathways	0.003	0.997	0.000
H47.4 Disorders of optic chiasm	0.003	0.997	0.000
S92.0 Fracture of calcaneus	0.003	0.997	0.000
S92.7 Multiple fractures of foot	0.003	0.997	0.000
Y52.2 Other antidysrhythmic drugs, not elsewhere classified	0.000	0.997	0.003
H10 Conjunctivitis	0.003	0.997	0.000
H21.1 Other vascular disorders of iris and ciliary body	0.003	0.997	0.000
H43.8 Other disorders of vitreous body	0.003	0.997	0.000
H43 Disorders of vitreous body	0.003	0.997	0.000
H21.2 Degeneration of iris and ciliary body	0.003	0.997	0.000
H48.8 Other disorders of optic nerve and visual pathways in diseases classified elsewhere	0.003	0.997	0.000
H48.1 Retrobulbar neuritis in diseases classified elsewhere	0.003	0.997	0.000
H48.0 Optic atrophy in diseases classified elsewhere	0.003	0.997	0.000
H58 Other disorders of eye and adnexa in diseases classified elsewhere	0.003	0.997	0.000
S92.3 Fracture of metatarsal bone	0.003	0.997	0.000
S92.1 Fracture of talus	0.003	0.997	0.000
H16.3 Interstitial and deep keratitis	0.003	0.997	0.000
H16.1 Other superficial keratitis without conjunctivitis	0.003	0.997	0.000
C68 Malignant neoplasm of other and unspecified urinary organs	0.003	0.997	0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level	0.003	0.997	0.000
G93 Other disorders of brain	0.000	0.997	0.003
H20.8 Other iridocyclitis	0.003	0.997	0.000
S92.9 Fracture of foot, unspecified	0.003	0.997	0.000
H44.0 Purulent endophthalmitis	0.003	0.997	0.000
H59.0 Vitreous syndrome following cataract surgery	0.003	0.997	0.000
I49.9 Cardiac arrhythmia, unspecified	0.003	0.997	0.000
H19.2 Keratitis and keratoconjunctivitis in other infectious and parasitic diseases classified elsewhere	0.003	0.997	0.000
S92.4 Fracture of great toe	0.003	0.997	0.000
H21.4 Pupillary membranes	0.003	0.997	0.000
H21.3 Cyst of iris, ciliary body and anterior chamber	0.003	0.997	0.000
S92.5 Fracture of other toe	0.003	0.997	0.000
C66 Malignant neoplasm of ureter	0.003	0.997	0.000
M24.85 Other specific joint derangements, not elsewhere classified (Pelvic region and thigh)	0.003	0.997	0.000
C68.0 Urethra	0.003	0.997	0.000
H22.1 Iridocyclitis in other diseases classified elsewhere	0.003	0.997	0.000
S91.7 Multiple open wounds of ankle and foot	0.003	0.997	0.000
S91.2 Open wound of toe(s) with damage to nail	0.003	0.997	0.000
H15.0 Scleritis	0.003	0.997	0.000
S96.9 Injury of unspecified muscle and tendon at ankle and foot level	0.003	0.997	0.000
H57 Other disorders of eye and adnexa	0.003	0.997	0.000
H22.8 Other disorders of iris and ciliary body in diseases classified elsewhere	0.003	0.997	0.000
H22.0 Iridocyclitis in infectious and parasitic diseases classified elsewhere	0.003	0.997	0.000
N60.0 Solitary cyst of breast	0.003	0.997	0.000
S92.00 Fracture of calcaneus (closed)	0.003	0.997	0.000
I86.1 Scrotal varices	0.003	0.997	0.000
H16.9 Keratitis, unspecified	0.003	0.997	0.000
H44.4 Hypotony of eye	0.003	0.997	0.000
R63.8 Other symptoms and signs concerning food and fluid intake	0.003	0.997	0.000
S96.8 Injury of other muscles and tendons at ankle and foot level	0.003	0.997	0.000
H21.9 Disorder of iris and ciliary body, unspecified	0.003	0.997	0.000
H17 Corneal scars and opacities	0.003	0.997	0.000
S92.70 Multiple fractures of foot (closed)	0.003	0.997	0.000
D52.9 Folate deficiency anaemia, unspecified	0.000	0.997	0.003
S92.2 Fracture of other tarsal bone(s)	0.003	0.997	0.000
H15.9 Disorder of sclera, unspecified	0.002	0.997	0.000
S96.7 Injury of multiple muscles and tendons at ankle and foot level	0.002	0.997	0.000
S96.2 Injury of intrinsic muscle and tendon at ankle and foot level	0.002	0.997	0.000
S96.0 Injury of muscle and tendon of long flexor muscle of toe at ankle and foot level	0.002	0.997	0.000
I21.0 Acute transmural myocardial infarction of anterior wall	0.000	0.997	0.003
D06.9 Cervix, unspecified	0.003	0.997	0.000
G93.8 Other specified disorders of brain	0.000	0.997	0.003
H03.1 Involvement of eyelid in other infectious diseases classified elsewhere	0.003	0.997	0.000
H27.8 Other specified disorders of lens	0.002	0.997	0.000
H45.8 Other disorders of vitreous body and globe in diseases classified elsewhere	0.002	0.997	0.000
H45.1 Endophthalmitis in diseases classified elsewhere	0.002	0.997	0.000
H45.0 Vitreous haemorrhage in diseases classified elsewhere	0.002	0.997	0.000
H47.1 Papilloedema, unspecified	0.002	0.997	0.000
H11.0 Pterygium	0.003	0.997	0.000
H19.8 Other disorders of sclera and cornea in diseases classified elsewhere	0.002	0.997	0.000
H19.0 Scleritis and episcleritis in diseases classified elsewhere	0.002	0.997	0.000
S96.1 Injury of muscle and tendon of long extensor muscle of toe at ankle and foot level	0.002	0.997	0.000
K52.2 Allergic and dietetic gastro-enteritis and colitis	0.002	0.997	0.000
H55 Nystagmus and other irregular eye movements	0.003	0.997	0.000
H44.9 Disorder of globe, unspecified	0.002	0.997	0.000
S97.8 Crushing injury of other parts of ankle and foot	0.002	0.997	0.000
H59.9 Postprocedural disorder of eye and adnexa, unspecified	0.002	0.997	0.000
S97.1 Crushing injury of toe(s)	0.002	0.997	0.000
S97.0 Crushing injury of ankle	0.002	0.997	0.000
H44.8 Other disorders of globe	0.002	0.997	0.000
H44.7 Retained (old) intraocular foreign body, nonmagnetic	0.002	0.997	0.000
H44.6 Retained (old) intraocular foreign body, magnetic	0.002	0.997	0.000
H44.5 Degenerated conditions of globe	0.002	0.997	0.000
H44.3 Other degenerative disorders of globe	0.002	0.997	0.000
S94.9 Injury of unspecified nerve at ankle and foot level	0.002	0.997	0.000
S94.8 Injury of other nerves at ankle and foot level	0.002	0.997	0.000
S94.7 Injury of multiple nerves at ankle and foot level	0.002	0.997	0.000
S94.3 Injury of cutaneous sensory nerve at ankle and foot level	0.002	0.997	0.000
S94.2 Injury of deep peroneal nerve at ankle and foot level	0.002	0.997	0.000
S94.1 Injury of medial plantar nerve	0.002	0.997	0.000
S94.0 Injury of lateral plantar nerve	0.002	0.997	0.000
S95.9 Injury of unspecified blood vessel at ankle and foot level	0.002	0.997	0.000
S95.8 Injury of other blood vessels at ankle and foot level	0.002	0.997	0.000
S95.7 Injury of multiple blood vessels at ankle and foot level	0.002	0.997	0.000
S95.2 Injury of dorsal vein of foot	0.002	0.997	0.000
S95.1 Injury of plantar artery of foot	0.002	0.997	0.000
S95.0 Injury of dorsal artery of foot	0.002	0.997	0.000
S98.4 Traumatic amputation of foot, level unspecified	0.002	0.997	0.000
S98.3 Traumatic amputation of other parts of foot	0.002	0.997	0.000
S98.2 Traumatic amputation of two or more toes	0.002	0.997	0.000
S98.1 Traumatic amputation of one toe	0.002	0.997	0.000
S98.0 Traumatic amputation of foot at ankle level	0.002	0.997	0.000
H57.8 Other specified disorders of eye and adnexa	0.002	0.997	0.000
G93.6 Cerebral oedema	0.000	0.997	0.003
H15.8 Other disorders of sclera	0.002	0.997	0.000
H15.1 Episcleritis	0.002	0.997	0.000
S92.01 Fracture of calcaneus (open)	0.002	0.997	0.000
H11.4 Other conjunctival vascular disorders and cysts	0.002	0.997	0.000
H19.3 Keratitis and keratoconjunctivitis in other diseases classified elsewhere	0.002	0.997	0.000
S92.71 Multiple fractures of foot (open)	0.002	0.998	0.000
H10.8 Other conjunctivitis	0.002	0.998	0.000
H10.5 Blepharoconjunctivitis	0.002	0.998	0.000
H10.3 Acute conjunctivitis, unspecified	0.002	0.998	0.000
H10.2 Other acute conjunctivitis	0.002	0.998	0.000
H10.1 Acute atopic conjunctivitis	0.002	0.998	0.000
H10.0 Mucopurulent conjunctivitis	0.002	0.998	0.000
S92.30 Fracture of metatarsal bone (closed)	0.002	0.998	0.000
H10.4 Chronic conjunctivitis	0.002	0.998	0.000
H43.3 Other vitreous opacities	0.002	0.998	0.000
L82 Seborrhoeic keratosis	0.000	0.998	0.002
S92.50 Fracture of other toe (closed)	0.002	0.998	0.000
H16.0 Corneal ulcer	0.002	0.998	0.000
K52.8 Other specified non-infective gastro-enteritis and colitis	0.002	0.998	0.000
S93.1 Dislocation of toe(s)	0.002	0.998	0.000
H18 Other disorders of cornea	0.002	0.998	0.000
G93.0 Cerebral cysts	0.000	0.998	0.002
H43.0 Vitreous prolapse	0.002	0.998	0.000
H58.9 Other specified disorders of eye and adnexa in diseases classified elsewhere	0.002	0.998	0.000
H58.1 Visual disturbances in diseases classified elsewhere	0.002	0.998	0.000
H58.0 Anomalies of pupillary function in diseases classified elsewhere	0.002	0.998	0.000
Y52 Agents primarily affecting the cardiovascular system	0.000	0.998	0.002
S92.10 Fracture of talus (closed)	0.002	0.998	0.000
S92.31 Fracture of metatarsal bone (open)	0.002	0.998	0.000
M21.26 Flexion deformity (Lower leg)	0.002	0.998	0.000
S12.10 Fracture of second cervical vertebra (closed)	0.002	0.998	0.000
X62.9 Unspecified place	0.000	0.998	0.002
H25 Senile cataract	0.002	0.998	0.000
S92.11 Fracture of talus (open)	0.002	0.998	0.000
C68.9 Urinary organ, unspecified	0.002	0.998	0.000
C68.8 Overlapping lesion of urinary organs	0.002	0.998	0.000
C68.1 Paraurethral glands	0.002	0.998	0.000
G93.7 Reye's syndrome	0.000	0.998	0.002
H11.1 Conjunctival degenerations and deposits	0.002	0.998	0.000
H21.8 Other specified disorders of iris and ciliary body	0.002	0.998	0.000
S93.4 Sprain and strain of ankle	0.002	0.998	0.000
S93.6 Sprain and strain of other and unspecified parts of foot	0.002	0.998	0.000
S93.5 Sprain and strain of toe(s)	0.002	0.998	0.000
S93.2 Rupture of ligaments at ankle and foot level	0.002	0.998	0.000
S92.91 Fracture of foot, unspecified (open)	0.002	0.998	0.000
S92.90 Fracture of foot, unspecified (closed)	0.002	0.998	0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction	0.000	0.998	0.002
Q50.4 Embryonic cyst of Fallopian tube	0.002	0.998	0.000
I86 Varicose veins of other sites	0.002	0.998	0.000
B02.9 Zoster without complication	0.002	0.998	0.000
H43.9 Disorder of vitreous body, unspecified	0.002	0.998	0.000
H43.2 Crystalline deposits in vitreous body	0.002	0.998	0.000
G93.5 Compression of brain	0.000	0.998	0.002
H18.3 Changes in corneal membranes	0.002	0.998	0.000
R44.1 Visual hallucinations	0.002	0.998	0.000
S91.1 Open wound of toe(s) without damage to nail	0.002	0.998	0.000
Y52.3 Coronary vasodilators, not elsewhere classified	0.000	0.998	0.002
M21.17 Varus deformity, not elsewhere classified (Ankle and foot)	0.002	0.998	0.000
S92.40 Fracture of great toe (closed)	0.002	0.998	0.000
D09.0 Bladder	0.002	0.998	0.000
H21.5 Other adhesions and disruptions of iris and ciliary body	0.002	0.998	0.000
I84.3 External thrombosed haemorrhoids	0.002	0.998	0.000
M79.10 Myalgia (Multiple sites)	0.002	0.998	0.000
S92.41 Fracture of great toe (open)	0.002	0.998	0.000
H19.1 Herpesviral keratitis and keratoconjunctivitis	0.002	0.998	0.000
N28.8 Other specified disorders of kidney and ureter	0.000	0.998	0.002
H44.1 Other endophthalmitis	0.002	0.998	0.000
S92.21 Fracture of other tarsal bone(s) (open)	0.002	0.998	0.000
G93.1 Anoxic brain damage, not elsewhere classified	0.000	0.998	0.002
H17.1 Other central corneal opacity	0.002	0.998	0.000
H17.0 Adherent leukoma	0.002	0.998	0.000
H58.8 Visual disturbances in diseases classified elsewhere	0.002	0.998	0.000
S91.0 Open wound of ankle	0.002	0.998	0.000
S93.3 Dislocation of other and unspecified parts of foot	0.002	0.998	0.000
H03 Disorders of eyelid in diseases classified elsewhere	0.002	0.998	0.000
F02.3 Dementia in Parkinson's disease	0.002	0.998	0.000
S12.1 Fracture of second cervical vertebra	0.002	0.998	0.000
M24.67 Ankylosis of joint (Ankle and foot)	0.002	0.998	0.000
H18.2 Other corneal oedema	0.002	0.998	0.000
R76.8 Other specified abnormal immunological findings in serum	0.000	0.998	0.002
G93.4 Encephalopathy, unspecified	0.000	0.998	0.002
N81.5 Vaginal enterocele	0.002	0.998	0.000
Y52.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.000	0.998	0.002
H18.0 Corneal pigmentations and deposits	0.002	0.998	0.000
H57.9 Disorder of eye and adnexa, unspecified	0.002	0.998	0.000
K57.0 Diverticular disease of small intestine with perforation and abscess	0.002	0.998	0.000
H05.2 Exophthalmic conditions	0.002	0.998	0.000
H90.5 Sensorineural hearing loss, unspecified	0.002	0.998	0.000
D68.9 Coagulation defect, unspecified	0.000	0.998	0.002
S93.0 Dislocation of ankle joint	0.002	0.998	0.000
S92.51 Fracture of other toe (open)	0.002	0.998	0.000
N70.1 Chronic salpingitis and oophoritis	0.000	0.998	0.002
S12.90 Fracture of neck, part unspecified (closed)	0.002	0.998	0.000
H18.7 Other corneal deformities	0.002	0.998	0.000
H44.2 Degenerative myopia	0.002	0.998	0.000
S12 Fracture of neck	0.002	0.998	0.000
S92.20 Fracture of other tarsal bone(s) (closed)	0.002	0.998	0.000
Y52.8 Antivaricose drugs, including sclerosing agents	0.000	0.998	0.002
Y52.7 Peripheral vasodilators	0.000	0.998	0.002
S12.9 Fracture of neck, part unspecified	0.002	0.998	0.000
H25.2 Senile cataract, morgagnian type	0.002	0.998	0.000
M21.2 Flexion deformity	0.002	0.998	0.000
M21.27 Flexion deformity (Ankle and foot)	0.002	0.998	0.000
S93.40 Sprain of unspecified ligament of ankle	0.002	0.998	0.000
Q50.5 Embryonic cyst of broad ligament	0.002	0.998	0.000
Y52.9 Other and unspecified agents primarily affecting the cardiovascular system	0.000	0.998	0.002
H17.8 Other corneal scars and opacities	0.002	0.998	0.000
H18.1 Bullous keratopathy	0.002	0.998	0.000
I86.0 Sublingual varices	0.002	0.998	0.000
S12.2 Fracture of other specified cervical vertebra	0.002	0.998	0.000
S12.0 Fracture of first cervical vertebra	0.002	0.998	0.000
S12.00 Fracture of first cervical vertebra (closed)	0.002	0.998	0.000
S12.20 Fracture of other specified cervical vertebra (closed)	0.002	0.998	0.000
H57.1 Ocular pain	0.002	0.998	0.000
I86.3 Vulval varices	0.002	0.998	0.000
M24.8 Other specific joint derangements, not elsewhere classified	0.002	0.998	0.000
M24.6 Ankylosis of joint	0.002	0.998	0.000
Y88 Sequelae of surgical and medical care as external cause	0.002	0.998	0.000
I86.8 Varicose veins of other specified sites	0.002	0.998	0.000
T81.3 Disruption of operation wound, not elsewhere classified	0.002	0.998	0.000
M24.66 Ankylosis of joint (Lower leg)	0.002	0.998	0.000
H61.0 Perichondritis of external ear	0.000	0.998	0.002
Y52.0 Cardiac-stimulant glycosides and drugs of similar action	0.000	0.998	0.002
Q50 Congenital malformations of ovaries, Fallopian tubes and broad ligaments	0.002	0.998	0.000
H10.9 Conjunctivitis, unspecified	0.002	0.998	0.000
H03.8 Involvement of eyelid in other diseases classified elsewhere	0.002	0.998	0.000
H03.0 Parasitic infestation of eyelid in diseases classified elsewhere	0.002	0.998	0.000
H17.9 Corneal scar and opacity, unspecified	0.002	0.998	0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit	0.002	0.998	0.000
S12.11 Fracture of second cervical vertebra (open)	0.002	0.998	0.000
H18.9 Disorder of cornea, unspecified	0.002	0.998	0.000
H57.0 Anomalies of pupillary function	0.002	0.998	0.000
M06.00 Seronegative rheumatoid arthritis (Multiple sites)	0.000	0.998	0.002
M21.67 Other acquired deformities of ankle and foot-Ankle/foot	0.002	0.998	0.000
I49.5 Sick sinus syndrome	0.000	0.998	0.002
I86.2 Pelvic varices	0.002	0.998	0.000
M21.1 Varus deformity, not elsewhere classified	0.002	0.998	0.000
S12.7 Multiple fractures of cervical spine	0.002	0.998	0.000
M24.64 Ankylosis of joint (Hand)	0.002	0.998	0.000
Y52.4 Angiotensin-converting-enzyme inhibitors	0.000	0.998	0.002
H18.5 Hereditary corneal dystrophies	0.002	0.998	0.000
K74.6 Other and unspecified cirrhosis of liver	0.002	0.998	0.000
H05 Disorders of orbit	0.002	0.998	0.000
M24.84 Other specific joint derangements, not elsewhere classified (Hand)	0.002	0.998	0.000
M46.92 Inflammatory spondylopathy, unspecified (Cervical region)	0.000	0.998	0.002
C25.9 Pancreas, unspecified	0.000	0.998	0.002
H18.8 Other specified disorders of cornea	0.002	0.998	0.000
K52.0 Gastro-enteritis and colitis due to radiation	0.001	0.998	0.000
K76.9 Liver disease, unspecified	0.002	0.998	0.000
L02.2 Cutaneous abscess, furuncle and carbuncle of trunk	0.002	0.998	0.000
S12.8 Fracture of other parts of neck	0.002	0.998	0.000
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere	0.002	0.998	0.000
M21.29 Flexion deformity (Site unspecified)	0.002	0.998	0.000
M21.28 Flexion deformity (Other)	0.002	0.998	0.000
M21.23 Flexion deformity (Forearm)	0.002	0.998	0.000
M21.22 Flexion deformity (Upper arm)	0.002	0.998	0.000
M21.21 Flexion deformity (Shoulder region)	0.002	0.998	0.000
M21.20 Flexion deformity (Multiple sites)	0.002	0.998	0.000
S12.91 Fracture of neck, part unspecified (open)	0.002	0.998	0.000
K74.3 Primary biliary cirrhosis	0.002	0.998	0.000
S06.20 Diffuse brain injury (without open intracranial wound)	0.000	0.998	0.002
K92.9 Disease of digestive system, unspecified	0.002	0.998	0.000
M21.6 Other acquired deformities of ankle and foot	0.002	0.998	0.000
S12.01 Fracture of first cervical vertebra (open)	0.001	0.998	0.000
S12.21 Fracture of other specified cervical vertebra (open)	0.001	0.998	0.000
M24.89 Other specific joint derangements, not elsewhere classified (Site unspecified)	0.002	0.998	0.000
M24.88 Other specific joint derangements, not elsewhere classified (Other)	0.002	0.998	0.000
M24.82 Other specific joint derangements, not elsewhere classified (Upper arm)	0.002	0.998	0.000
M24.80 Other specific joint derangements, not elsewhere classified (Multiple sites)	0.002	0.998	0.000
M80.00 Postmenopausal osteoporosis with pathological fracture (Multiple sites)	0.002	0.998	0.000
G93.2 Benign intracranial hypertension	0.000	0.998	0.001
H18.4 Corneal degeneration	0.002	0.998	0.000
K70.3 Alcoholic cirrhosis of liver	0.002	0.998	0.000
R01.1 Cardiac murmur, unspecified	0.002	0.998	0.000
M21.25 Flexion deformity (Pelvic region and thigh)	0.001	0.998	0.000
M24.26 Disorder of ligament (Lower leg)	0.002	0.998	0.000
M24.69 Ankylosis of joint (Site unspecified)	0.001	0.998	0.000
M24.68 Ankylosis of joint (Other)	0.001	0.998	0.000
M24.65 Ankylosis of joint (Pelvic region and thigh)	0.001	0.998	0.000
M24.63 Ankylosis of joint (Forearm)	0.001	0.998	0.000
M24.62 Ankylosis of joint (Upper arm)	0.001	0.998	0.000
M24.61 Ankylosis of joint (Shoulder region)	0.001	0.998	0.000
M24.60 Ankylosis of joint (Multiple sites)	0.001	0.998	0.000
M24.87 Other specific joint derangements, not elsewhere classified (Ankle and foot)	0.002	0.998	0.000
M24.83 Other specific joint derangements, not elsewhere classified (Forearm)	0.002	0.998	0.000
S12.70 Multiple fractures of cervical spine (closed)	0.002	0.998	0.000
N36.3 Prolapsed urethral mucosa	0.002	0.998	0.000
Q12.0 Congenital cataract	0.002	0.998	0.000
Y88.2 Sequelae of adverse incidents associated with medical devices in diagnostic and therapeutic use	0.001	0.998	0.000
Y88.1 Sequelae of misadventures to patients during surgical and medical procedures	0.001	0.998	0.000
Y88.0 Sequelae of adverse effects caused by drugs, medicaments and biological substances in therapeutic use	0.001	0.998	0.000
K74 Fibrosis and cirrhosis of liver	0.002	0.998	0.000
M24.81 Other specific joint derangements, not elsewhere classified (Shoulder region)	0.002	0.998	0.000
F02.8 Dementia in other specified diseases classified elsewhere	0.002	0.998	0.000
H06.2 Dysthyroid exophthalmos	0.002	0.998	0.000
K70.2 Alcoholic fibrosis and sclerosis of liver	0.002	0.998	0.000
R07.1 Chest pain on breathing	0.002	0.998	0.000
Z03.4 Observation for suspected myocardial infarction	0.000	0.998	0.002
Q50.6 Other congenital malformatons of Fallopian tube and broad ligament	0.001	0.998	0.000
Q50.3 Other congenital malformations of ovary	0.001	0.998	0.000
Q50.2 Congenital torsion of ovary	0.001	0.998	0.000
Q50.1 Developmental ovarian cyst	0.001	0.998	0.000
Q50.0 Congenital absence of ovary	0.001	0.998	0.000
K52.1 Toxic gastro-enteritis and colitis	0.001	0.998	0.000
Y52.1 Calcium-channel blockers	0.000	0.998	0.001
M21 Other acquired deformities of limbs	0.002	0.998	0.000
M21.19 Varus deformity, not elsewhere classified (Site unspecified)	0.001	0.998	0.000
M21.18 Varus deformity, not elsewhere classified (Other)	0.001	0.998	0.000
M21.15 Varus deformity, not elsewhere classified (Pelvic region and thigh)	0.001	0.998	0.000
M21.14 Varus deformity, not elsewhere classified (Hand)	0.001	0.998	0.000
M21.13 Varus deformity, not elsewhere classified (Forearm)	0.001	0.998	0.000
M21.12 Varus deformity, not elsewhere classified (Upper arm)	0.001	0.998	0.000
M21.11 Varus deformity, not elsewhere classified (Shoulder region)	0.001	0.998	0.000
M21.10 Varus deformity, not elsewhere classified (Multiple sites)	0.001	0.998	0.000
F02 Dementia in other diseases classified elsewhere	0.002	0.998	0.000
S12.71 Multiple fractures of cervical spine (open)	0.001	0.998	0.000
K74.0 Hepatic fibrosis	0.002	0.998	0.000
H05.5 Retained (old) foreign body following penetrating wound of orbit	0.001	0.998	0.000
H05.3 Deformity of orbit	0.001	0.998	0.000
H05.1 Chronic inflammatory disorders of orbit	0.001	0.998	0.000
O35.1 Maternal care for (suspected) chromosomal abnormality in foetus	0.002	0.998	0.000
L43 Lichen planus	0.000	0.998	0.001
M21.06 Valgus deformity, not elsewhere classified (Lower leg)	0.001	0.998	0.000
H05.4 Enophthalmos	0.001	0.998	0.000
M21.9 Acquired deformity of limb, unspecified	0.001	0.998	0.000
M21.8 Other specified acquired deformities of limbs	0.001	0.998	0.000
S12.81 Fracture of other parts of neck (open)	0.001	0.998	0.000
S12.80 Fracture of other parts of neck (closed)	0.001	0.998	0.000
N60.4 Mammary duct ectasia	0.002	0.998	0.000
H06.3 Other disorders of orbit in diseases classified elsewhere	0.001	0.998	0.000
H06.1 Parasitic infestation of orbit in diseases classified elsewhere	0.001	0.998	0.000
H06.0 Disorders of lachrymal system in diseases classified elsewhere	0.001	0.998	0.000
Y87.0 Sequelae of intentional self-harm	0.001	0.998	0.000
I50 Heart failure	0.000	0.998	0.002
M21.69 Other acquired deformities of ankle and foot-Site unspec	0.001	0.998	0.000
M21.68 Other acquired deformities of ankle and foot-Other	0.001	0.998	0.000
M21.66 Other acquired deformities of ankle and foot-Lower leg	0.001	0.998	0.000
M21.65 Other acquired deformities of ankle and foot-Pelvic/thigh	0.001	0.998	0.000
M21.64 Other acquired deformities of ankle and foot-Hand	0.001	0.998	0.000
M21.63 Other acquired deformities of ankle and foot-Forearm	0.001	0.998	0.000
M21.62 Other acquired deformities of ankle and foot-Upper arm	0.001	0.998	0.000
M21.61 Other acquired deformities of ankle and foot-Shldr region	0.001	0.998	0.000
M21.60 Other acquired deformities of ankle and foot-Mult sites	0.001	0.998	0.000
M21.86 Other specified acquired deformities of limbs (Lower leg)	0.001	0.998	0.000
M21.97 Acquired deformity of limb, unspecified (Ankle and foot)	0.001	0.998	0.000
I50.9 Heart failure, unspecified	0.000	0.998	0.002
G40.2 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures	0.001	0.999	0.000
H18.6 Keratoconus	0.001	0.999	0.000
K70.0 Alcoholic fatty liver	0.001	0.999	0.000
K74.5 Biliary cirrhosis, unspecified	0.001	0.999	0.000
M21.4 Flat foot [pes planus] (acquired)	0.001	0.999	0.000
N60.8 Other benign mammary dysplasias	0.001	0.999	0.000
M21.24 Flexion deformity (Hand)	0.001	0.999	0.000
H05.9 Disorder of orbit, unspecified	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations