TreeWAS – Variant ID: rs4729260

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
M81.9 Osteoporosis, unspecified	0.000	0.549	0.451
M81 Osteoporosis without pathological fracture	0.000	0.553	0.447
M81.99 Osteoporosis, unspecified (Site unspecified)	0.000	0.557	0.443
M80-M85 Disorders of bone density and structure	0.000	0.559	0.441
M85 Other disorders of bone density and structure	0.000	0.566	0.434
M85.8 Other specified disorders of bone density and structure	0.000	0.575	0.425
M80 Osteoporosis with pathological fracture	0.000	0.576	0.424
M85.89 Other specified disorders of bone density and structure (Site unspecified)	0.000	0.581	0.419
M80.1 Postoophorectomy osteoporosis with pathological fracture	0.000	0.596	0.404
M80.10 Postoophorectomy osteoporosis with pathological fracture (Multiple sites)	0.000	0.610	0.390
M81.93 Osteoporosis, unspecified (Forearm)	0.000	0.612	0.388
M85.6 Other cyst of bone	0.000	0.630	0.370
M81.95 Osteoporosis, unspecified (Pelvic region and thigh)	0.000	0.631	0.369
M81.2 Osteoporosis of disuse	0.000	0.631	0.369
M81.4 Drug-induced osteoporosis	0.000	0.632	0.368
M80.5 Idiopathic osteoporosis with pathological fracture	0.000	0.640	0.360
M81.96 Osteoporosis, unspecified (Lower leg)	0.000	0.645	0.355
M81.97 Osteoporosis, unspecified (Ankle and foot)	0.000	0.646	0.354
M85.88 Other specified disorders of bone density and structure (Other)	0.000	0.649	0.351
M85.2 Hyperostosis of skull	0.000	0.652	0.348
M81.90 Osteoporosis, unspecified (Multiple sites)	0.000	0.653	0.347
M85.87 Other specified disorders of bone density and structure (Ankle and foot)	0.000	0.655	0.345
M81.3 Postsurgical malabsorption osteoporosis	0.000	0.660	0.340
M81.92 Osteoporosis, unspecified (Upper arm)	0.000	0.677	0.323
M84 Disorders of continuity of bone	0.000	0.677	0.323
M85.68 Other cyst of bone (Other)	0.000	0.677	0.323
M81.1 Postoophorectomy osteoporosis	0.000	0.679	0.321
M81.6 Localised osteoporosis [Lequesne]	0.000	0.679	0.321
M81.5 Idiopathic osteoporosis	0.000	0.679	0.321
M80.8 Other osteoporosis with pathological fracture	0.000	0.683	0.317
M81.91 Osteoporosis, unspecified (Shoulder region)	0.000	0.685	0.315
M81.94 Osteoporosis, unspecified (Hand)	0.000	0.687	0.313
M81.20 Osteoporosis of disuse (Multiple sites)	0.000	0.687	0.313
M85.0 Fibrous dysplasia (monostotic)	0.000	0.688	0.312
M85.5 Aneurysmal bone cyst	0.000	0.688	0.311
M85.3 Osteitis condensans	0.000	0.688	0.311
M85.1 Skeletal fluorosis	0.000	0.688	0.311
M81.98 Osteoporosis, unspecified (Other)	0.000	0.691	0.309
M85.64 Other cyst of bone (Hand)	0.000	0.692	0.308
M85.84 Other specified disorders of bone density and structure (Hand)	0.000	0.695	0.305
M85.81 Other specified disorders of bone density and structure (Shoulder region)	0.000	0.695	0.305
M80.4 Drug-induced osteoporosis with pathological fracture	0.000	0.696	0.304
M80.3 Postsurgical malabsorption osteoporosis with pathological fracture	0.000	0.696	0.304
M80.2 Osteoporosis of disuse with pathological fracture	0.000	0.696	0.304
M81.49 Drug-induced osteoporosis (Site unspecified)	0.000	0.697	0.303
M85.9 Disorder of bone density and structure, unspecified	0.000	0.697	0.303
M80.52 Idiopathic osteoporosis with pathological fracture (Upper arm)	0.000	0.704	0.296
M85.83 Other specified disorders of bone density and structure (Forearm)	0.000	0.704	0.296
M81.0 Postmenopausal osteoporosis	0.000	0.706	0.294
M83 Adult osteomalacia	0.000	0.706	0.294
M80.9 Unspecified osteoporosis with pathological fracture	0.000	0.708	0.292
M80.19 Postoophorectomy osteoporosis with pathological fracture (Site unspecified)	0.000	0.710	0.290
M80.18 Postoophorectomy osteoporosis with pathological fracture (Other)	0.000	0.710	0.290
M80.17 Postoophorectomy osteoporosis with pathological fracture (Ankle and foot)	0.000	0.710	0.290
M80.16 Postoophorectomy osteoporosis with pathological fracture (Lower leg)	0.000	0.710	0.290
M80.15 Postoophorectomy osteoporosis with pathological fracture (Pelvic region and thigh)	0.000	0.710	0.290
M80.14 Postoophorectomy osteoporosis with pathological fracture (Hand)	0.000	0.710	0.290
M80.13 Postoophorectomy osteoporosis with pathological fracture (Forearm)	0.000	0.710	0.290
M80.12 Postoophorectomy osteoporosis with pathological fracture (Upper arm)	0.000	0.710	0.290
M80.11 Postoophorectomy osteoporosis with pathological fracture (Shoulder region)	0.000	0.710	0.290
M82 Osteoporosis in diseases classified elsewhere	0.000	0.712	0.287
M80.50 Idiopathic osteoporosis with pathological fracture (Multiple sites)	0.000	0.713	0.287
M85.85 Other specified disorders of bone density and structure (Pelvic region and thigh)	0.000	0.713	0.287
M85.82 Other specified disorders of bone density and structure (Upper arm)	0.000	0.721	0.279
M85.20 Hyperostosis of skull-Mult sites	0.000	0.721	0.279
M80.0 Postmenopausal osteoporosis with pathological fracture	0.000	0.721	0.279
M85.66 Other cyst of bone (Lower leg)	0.000	0.722	0.278
M81.40 Drug-induced osteoporosis (Multiple sites)	0.000	0.722	0.278
M81.8 Other osteoporosis	0.000	0.725	0.275
M85.80 Other specified disorders of bone density and structure (Multiple sites)	0.000	0.728	0.272
M85.86 Other specified disorders of bone density and structure (Lower leg)	0.000	0.729	0.271
M85.69 Other cyst of bone (Site unspecified)	0.000	0.734	0.265
M85.63 Other cyst of bone (Forearm)	0.000	0.734	0.265
M85.62 Other cyst of bone (Upper arm)	0.000	0.734	0.265
M85.61 Other cyst of bone (Shoulder region)	0.000	0.734	0.265
M85.60 Other cyst of bone (Multiple sites)	0.000	0.734	0.265
M81.29 Osteoporosis of disuse (Site unspecified)	0.000	0.735	0.264
M81.28 Osteoporosis of disuse (Other)	0.000	0.735	0.264
M81.27 Osteoporosis of disuse (Ankle and foot)	0.000	0.735	0.264
M81.26 Osteoporosis of disuse (Lower leg)	0.000	0.735	0.264
M81.25 Osteoporosis of disuse (Pelvic region and thigh)	0.000	0.735	0.264
M81.24 Osteoporosis of disuse (Hand)	0.000	0.735	0.264
M81.23 Osteoporosis of disuse (Forearm)	0.000	0.735	0.264
M81.22 Osteoporosis of disuse (Upper arm)	0.000	0.735	0.264
M81.21 Osteoporosis of disuse (Shoulder region)	0.000	0.735	0.264
M81.48 Drug-induced osteoporosis (Other)	0.000	0.736	0.264
M81.47 Drug-induced osteoporosis (Ankle and foot)	0.000	0.736	0.264
M81.46 Drug-induced osteoporosis (Lower leg)	0.000	0.736	0.264
M81.45 Drug-induced osteoporosis (Pelvic region and thigh)	0.000	0.736	0.264
M81.44 Drug-induced osteoporosis (Hand)	0.000	0.736	0.264
M81.43 Drug-induced osteoporosis (Forearm)	0.000	0.736	0.264
M81.42 Drug-induced osteoporosis (Upper arm)	0.000	0.736	0.264
M81.41 Drug-induced osteoporosis (Shoulder region)	0.000	0.736	0.264
M81.30 Postsurgical malabsorption osteoporosis (Multiple sites)	0.000	0.737	0.263
M85.4 Solitary bone cyst	0.000	0.739	0.261
M85.22 Hyperostosis of skull-Upper arm	0.000	0.739	0.261
M84.8 Other disorders of continuity of bone	0.000	0.740	0.260
M80.59 Idiopathic osteoporosis with pathological fracture (Site unspecified)	0.000	0.742	0.258
M80.58 Idiopathic osteoporosis with pathological fracture (Other)	0.000	0.742	0.258
M80.57 Idiopathic osteoporosis with pathological fracture (Ankle and foot)	0.000	0.742	0.258
M80.56 Idiopathic osteoporosis with pathological fracture (Lower leg)	0.000	0.742	0.258
M80.55 Idiopathic osteoporosis with pathological fracture (Pelvic region and thigh)	0.000	0.742	0.258
M80.54 Idiopathic osteoporosis with pathological fracture (Hand)	0.000	0.742	0.258
M80.53 Idiopathic osteoporosis with pathological fracture (Forearm)	0.000	0.742	0.258
M80.51 Idiopathic osteoporosis with pathological fracture (Shoulder region)	0.000	0.742	0.258
M85.29 Hyperostosis of skull-Site unspec	0.000	0.750	0.250
M85.28 Hyperostosis of skull-Other	0.000	0.750	0.250
M85.27 Hyperostosis of skull-Ankle/Foot	0.000	0.750	0.250
M85.26 Hyperostosis of skull-Lower Leg	0.000	0.750	0.250
M85.25 Hyperostosis of skull-Pelvic/Thigh	0.000	0.750	0.250
M85.24 Hyperostosis of skull-Hand	0.000	0.750	0.250
M85.23 Hyperostosis of skull-Forearm	0.000	0.750	0.250
M85.21 Hyperostosis of skull-Shldr region	0.000	0.750	0.250
M84.0 Malunion of fracture	0.000	0.752	0.248
M84.3 Stress fracture, not elsewhere classified	0.000	0.754	0.246
M81.39 Postsurgical malabsorption osteoporosis (Site unspecified)	0.000	0.756	0.244
M81.38 Postsurgical malabsorption osteoporosis (Other)	0.000	0.756	0.244
M81.37 Postsurgical malabsorption osteoporosis (Ankle and foot)	0.000	0.756	0.244
M81.36 Postsurgical malabsorption osteoporosis (Lower leg)	0.000	0.756	0.244
M81.35 Postsurgical malabsorption osteoporosis (Pelvic region and thigh)	0.000	0.756	0.244
M81.34 Postsurgical malabsorption osteoporosis (Hand)	0.000	0.756	0.244
M81.33 Postsurgical malabsorption osteoporosis (Forearm)	0.000	0.756	0.244
M81.32 Postsurgical malabsorption osteoporosis (Upper arm)	0.000	0.756	0.244
M81.31 Postsurgical malabsorption osteoporosis (Shoulder region)	0.000	0.756	0.244
M85.65 Other cyst of bone (Pelvic region and thigh)	0.000	0.758	0.242
M85.00 Fibrous dysplasia (monostotic) (Multiple sites)	0.000	0.759	0.241
M80.81 Other osteoporosis with pathological fracture (Shoulder region)	0.000	0.764	0.236
M84.2 Delayed union of fracture	0.000	0.764	0.236
M80.90 Unspecified osteoporosis with pathological fracture (Multiple sites)	0.000	0.764	0.236
M80.88 Other osteoporosis with pathological fracture (Other)	0.000	0.767	0.233
M84.9 Disorder of continuity of bone, unspecified	0.000	0.768	0.232
M81.10 Postoophorectomy osteoporosis (Multiple sites)	0.000	0.769	0.231
M81.19 Postoophorectomy osteoporosis (Site unspecified)	0.000	0.769	0.230
M81.18 Postoophorectomy osteoporosis (Other)	0.000	0.769	0.230
M81.17 Postoophorectomy osteoporosis (Ankle and foot)	0.000	0.769	0.230
M81.16 Postoophorectomy osteoporosis (Lower leg)	0.000	0.769	0.230
M81.15 Postoophorectomy osteoporosis (Pelvic region and thigh)	0.000	0.769	0.230
M81.14 Postoophorectomy osteoporosis (Hand)	0.000	0.769	0.230
M81.13 Postoophorectomy osteoporosis (Forearm)	0.000	0.769	0.230
M81.12 Postoophorectomy osteoporosis (Upper arm)	0.000	0.769	0.230
M81.11 Postoophorectomy osteoporosis (Shoulder region)	0.000	0.769	0.230
M81.59 Idiopathic osteoporosis (Site unspecified)	0.000	0.770	0.230
M81.58 Idiopathic osteoporosis (Other)	0.000	0.770	0.230
M81.57 Idiopathic osteoporosis (Ankle and foot)	0.000	0.770	0.230
M81.56 Idiopathic osteoporosis (Lower leg)	0.000	0.770	0.230
M81.55 Idiopathic osteoporosis (Pelvic region and thigh)	0.000	0.770	0.230
M81.54 Idiopathic osteoporosis (Hand)	0.000	0.770	0.230
M81.53 Idiopathic osteoporosis (Forearm)	0.000	0.770	0.230
M81.52 Idiopathic osteoporosis (Upper arm)	0.000	0.770	0.230
M81.51 Idiopathic osteoporosis (Shoulder region)	0.000	0.770	0.230
M81.50 Idiopathic osteoporosis (Multiple sites)	0.000	0.770	0.230
M81.69 Localized osteoporosis [Lequesne] (Site unspecified)	0.000	0.770	0.230
M81.68 Localized osteoporosis [Lequesne] (Other)	0.000	0.770	0.230
M81.67 Localized osteoporosis [Lequesne] (Ankle and foot)	0.000	0.770	0.230
M81.66 Localized osteoporosis [Lequesne] (Lower leg)	0.000	0.770	0.230
M81.65 Localized osteoporosis [Lequesne] (Pelvic region and thigh)	0.000	0.770	0.230
M81.64 Localized osteoporosis [Lequesne] (Hand)	0.000	0.770	0.230
M81.63 Localized osteoporosis [Lequesne] (Forearm)	0.000	0.770	0.230
M81.62 Localized osteoporosis [Lequesne] (Upper arm)	0.000	0.770	0.230
M81.61 Localized osteoporosis [Lequesne] (Shoulder region)	0.000	0.770	0.230
M81.60 Localized osteoporosis [Lequesne] (Multiple sites)	0.000	0.770	0.230
M83.8 Other adult osteomalacia	0.000	0.772	0.228
M80.89 Other osteoporosis with pathological fracture (Site unspecified)	0.000	0.772	0.228
M80.87 Other osteoporosis with pathological fracture (Ankle and foot)	0.000	0.772	0.228
M80.86 Other osteoporosis with pathological fracture (Lower leg)	0.000	0.772	0.228
M80.85 Other osteoporosis with pathological fracture (Pelvic region and thigh)	0.000	0.772	0.228
M80.84 Other osteoporosis with pathological fracture (Hand)	0.000	0.772	0.228
M80.83 Other osteoporosis with pathological fracture (Forearm)	0.000	0.772	0.228
M80.82 Other osteoporosis with pathological fracture (Upper arm)	0.000	0.772	0.228
M80.80 Other osteoporosis with pathological fracture (Multiple sites)	0.000	0.772	0.228
M85.09 Fibrous dysplasia (monostotic) (Site unspecified)	0.000	0.776	0.224
M85.07 Fibrous dysplasia (monostotic) (Ankle and foot)	0.000	0.776	0.224
M85.06 Fibrous dysplasia (monostotic) (Lower leg)	0.000	0.776	0.224
M85.05 Fibrous dysplasia (monostotic) (Pelvic region and thigh)	0.000	0.776	0.224
M85.04 Fibrous dysplasia (monostotic) (Hand)	0.000	0.776	0.224
M85.03 Fibrous dysplasia (monostotic) (Forearm)	0.000	0.776	0.224
M85.02 Fibrous dysplasia (monostotic) (Upper arm)	0.000	0.776	0.224
M85.01 Fibrous dysplasia (monostotic) (Shoulder region)	0.000	0.776	0.224
M85.19 Skeletal fluorosis (Site unspecified)	0.000	0.776	0.223
M85.18 Skeletal fluorosis (Other)	0.000	0.776	0.223
M85.17 Skeletal fluorosis (Ankle and foot)	0.000	0.776	0.223
M85.16 Skeletal fluorosis (Lower leg)	0.000	0.776	0.223
M85.15 Skeletal fluorosis (Pelvic region and thigh)	0.000	0.776	0.223
M85.14 Skeletal fluorosis (Hand)	0.000	0.776	0.223
M85.13 Skeletal fluorosis (Forearm)	0.000	0.776	0.223
M85.12 Skeletal fluorosis (Upper arm)	0.000	0.776	0.223
M85.11 Skeletal fluorosis (Shoulder region)	0.000	0.776	0.223
M85.10 Skeletal fluorosis (Multiple sites)	0.000	0.776	0.223
M85.39 Osteitis condensans (Site unspecified)	0.000	0.776	0.223
M85.38 Osteitis condensans (Other)	0.000	0.776	0.223
M85.37 Osteitis condensans (Ankle and foot)	0.000	0.776	0.223
M85.36 Osteitis condensans (Lower leg)	0.000	0.776	0.223
M85.35 Osteitis condensans (Pelvic region and thigh)	0.000	0.776	0.223
M85.34 Osteitis condensans (Hand)	0.000	0.776	0.223
M85.33 Osteitis condensans (Forearm)	0.000	0.776	0.223
M85.32 Osteitis condensans (Upper arm)	0.000	0.776	0.223
M85.31 Osteitis condensans (Shoulder region)	0.000	0.776	0.223
M85.30 Osteitis condensans (Multiple sites)	0.000	0.776	0.223
M85.59 Aneurysmal bone cyst (Site unspecified)	0.000	0.776	0.223
M85.58 Aneurysmal bone cyst (Other)	0.000	0.776	0.223
M85.57 Aneurysmal bone cyst (Ankle and foot)	0.000	0.776	0.223
M85.56 Aneurysmal bone cyst (Lower leg)	0.000	0.776	0.223
M85.55 Aneurysmal bone cyst (Pelvic region and thigh)	0.000	0.776	0.223
M85.54 Aneurysmal bone cyst (Hand)	0.000	0.776	0.223
M85.53 Aneurysmal bone cyst (Forearm)	0.000	0.776	0.223
M85.52 Aneurysmal bone cyst (Upper arm)	0.000	0.776	0.223
M85.51 Aneurysmal bone cyst (Shoulder region)	0.000	0.776	0.223
M85.50 Aneurysmal bone cyst (Multiple sites)	0.000	0.776	0.223
M85.95 Disorder of bone density and structure, unspecified (Pelvic region and thigh)	0.000	0.780	0.220
M80.29 Osteoporosis of disuse with pathological fracture (Site unspecified)	0.000	0.782	0.218
M80.28 Osteoporosis of disuse with pathological fracture (Other)	0.000	0.782	0.218
M80.27 Osteoporosis of disuse with pathological fracture (Ankle and foot)	0.000	0.782	0.218
M80.26 Osteoporosis of disuse with pathological fracture (Lower leg)	0.000	0.782	0.218
M80.25 Osteoporosis of disuse with pathological fracture (Pelvic region and thigh)	0.000	0.782	0.218
M80.24 Osteoporosis of disuse with pathological fracture (Hand)	0.000	0.782	0.218
M80.23 Osteoporosis of disuse with pathological fracture (Forearm)	0.000	0.782	0.218
M80.22 Osteoporosis of disuse with pathological fracture (Upper arm)	0.000	0.782	0.218
M80.21 Osteoporosis of disuse with pathological fracture (Shoulder region)	0.000	0.782	0.218
M80.20 Osteoporosis of disuse with pathological fracture (Multiple sites)	0.000	0.782	0.218
M80.39 Postsurgical malabsorption osteoporosis with pathological fracture (Site unspecified)	0.000	0.782	0.218
M80.38 Postsurgical malabsorption osteoporosis with pathological fracture (Other)	0.000	0.782	0.218
M80.37 Postsurgical malabsorption osteoporosis with pathological fracture (Ankle and foot)	0.000	0.782	0.218
M80.36 Postsurgical malabsorption osteoporosis with pathological fracture (Lower leg)	0.000	0.782	0.218
M80.35 Postsurgical malabsorption osteoporosis with pathological fracture (Pelvic region and thigh)	0.000	0.782	0.218
M80.34 Postsurgical malabsorption osteoporosis with pathological fracture (Hand)	0.000	0.782	0.218
M80.33 Postsurgical malabsorption osteoporosis with pathological fracture (Forearm)	0.000	0.782	0.218
M80.32 Postsurgical malabsorption osteoporosis with pathological fracture (Upper arm)	0.000	0.782	0.218
M80.31 Postsurgical malabsorption osteoporosis with pathological fracture (Shoulder region)	0.000	0.782	0.218
M80.30 Postsurgical malabsorption osteoporosis with pathological fracture (Multiple sites)	0.000	0.782	0.218
M80.49 Drug-induced osteoporosis with pathological fracture (Site unspecified)	0.000	0.782	0.218
M80.48 Drug-induced osteoporosis with pathological fracture (Other)	0.000	0.782	0.218
M80.47 Drug-induced osteoporosis with pathological fracture (Ankle and foot)	0.000	0.782	0.218
M80.46 Drug-induced osteoporosis with pathological fracture (Lower leg)	0.000	0.782	0.218
M80.45 Drug-induced osteoporosis with pathological fracture (Pelvic region and thigh)	0.000	0.782	0.218
M80.44 Drug-induced osteoporosis with pathological fracture (Hand)	0.000	0.782	0.218
M80.43 Drug-induced osteoporosis with pathological fracture (Forearm)	0.000	0.782	0.218
M80.42 Drug-induced osteoporosis with pathological fracture (Upper arm)	0.000	0.782	0.218
M80.41 Drug-induced osteoporosis with pathological fracture (Shoulder region)	0.000	0.782	0.218
M80.40 Drug-induced osteoporosis with pathological fracture (Multiple sites)	0.000	0.782	0.218
M81.09 Postmenopausal osteoporosis (Site unspecified)	0.000	0.782	0.217
M85.97 Disorder of bone density and structure, unspecified (Ankle and foot)	0.000	0.783	0.217
M85.96 Disorder of bone density and structure, unspecified (Lower leg)	0.000	0.783	0.217
M85.94 Disorder of bone density and structure, unspecified (Hand)	0.000	0.783	0.217
M85.93 Disorder of bone density and structure, unspecified (Forearm)	0.000	0.783	0.217
M85.92 Disorder of bone density and structure, unspecified (Upper arm)	0.000	0.783	0.217
M85.91 Disorder of bone density and structure, unspecified (Shoulder region)	0.000	0.783	0.217
M85.90 Disorder of bone density and structure, unspecified (Multiple sites)	0.000	0.783	0.217
M85.99 Disorder of bone density and structure, unspecified (Site unspecified)	0.000	0.783	0.216
M85.67 Other cyst of bone (Ankle and foot)	0.000	0.786	0.214
M84.07 Malunion of fracture (Ankle and foot)	0.000	0.786	0.214
M80.95 Unspecified osteoporosis with pathological fracture (Pelvic region and thigh)	0.000	0.789	0.211
M81.08 Postmenopausal osteoporosis (Other)	0.000	0.789	0.211
M81.07 Postmenopausal osteoporosis (Ankle and foot)	0.000	0.789	0.211
M81.06 Postmenopausal osteoporosis (Lower leg)	0.000	0.789	0.211
M81.05 Postmenopausal osteoporosis (Pelvic region and thigh)	0.000	0.789	0.211
M81.04 Postmenopausal osteoporosis (Hand)	0.000	0.789	0.211
M81.03 Postmenopausal osteoporosis (Forearm)	0.000	0.789	0.211
M81.02 Postmenopausal osteoporosis (Upper arm)	0.000	0.789	0.211
M81.01 Postmenopausal osteoporosis (Shoulder region)	0.000	0.789	0.211
M83.5 Other drug-induced osteomalacia in adults	0.000	0.789	0.211
M83.4 Aluminum bone disease	0.000	0.789	0.211
M83.2 Adult osteomalacia due to malabsorption	0.000	0.789	0.211
M83.0 Puerperal osteomalacia	0.000	0.789	0.211
M84.1 Nonunion of fracture [pseudarthrosis]	0.000	0.789	0.211
M84.87 Other disorders of continuity of bone (Ankle and foot)	0.000	0.789	0.211
M80.97 Unspecified osteoporosis with pathological fracture (Ankle and foot)	0.000	0.790	0.210
M80.96 Unspecified osteoporosis with pathological fracture (Lower leg)	0.000	0.790	0.210
M80.94 Unspecified osteoporosis with pathological fracture (Hand)	0.000	0.790	0.210
M80.93 Unspecified osteoporosis with pathological fracture (Forearm)	0.000	0.790	0.210
M80.92 Unspecified osteoporosis with pathological fracture (Upper arm)	0.000	0.790	0.210
M80.91 Unspecified osteoporosis with pathological fracture (Shoulder region)	0.000	0.790	0.210
M82.8 Osteoporosis in other diseases classified elsewhere	0.000	0.794	0.206
M82.0 Osteoporosis in multiple myelomatosis	0.000	0.794	0.206
M82.3 Osteoporosis in diseases classified elsewhere, Forearm	0.000	0.794	0.206
M85.98 Disorder of bone density and structure, unspecified (Other)	0.000	0.794	0.206
M85.08 Fibrous dysplasia (monostotic) (Other)	0.000	0.797	0.203
M80.09 Postmenopausal osteoporosis with pathological fracture (Site unspecified)	0.000	0.800	0.200
M80.08 Postmenopausal osteoporosis with pathological fracture (Other)	0.000	0.800	0.200
M80.07 Postmenopausal osteoporosis with pathological fracture (Ankle and foot)	0.000	0.800	0.200
M80.06 Postmenopausal osteoporosis with pathological fracture (Lower leg)	0.000	0.800	0.200
M80.05 Postmenopausal osteoporosis with pathological fracture (Pelvic region and thigh)	0.000	0.800	0.200
M80.04 Postmenopausal osteoporosis with pathological fracture (Hand)	0.000	0.800	0.200
M80.03 Postmenopausal osteoporosis with pathological fracture (Forearm)	0.000	0.800	0.200
M80.02 Postmenopausal osteoporosis with pathological fracture (Upper arm)	0.000	0.800	0.200
M80.01 Postmenopausal osteoporosis with pathological fracture (Shoulder region)	0.000	0.800	0.200
M83.1 Senile osteomalacia	0.000	0.802	0.198
M83.9 Adult osteomalacia, unspecified	0.000	0.802	0.197
M81.88 Other osteoporosis (Other)	0.000	0.802	0.197
M81.87 Other osteoporosis (Ankle and foot)	0.000	0.802	0.197
M81.86 Other osteoporosis (Lower leg)	0.000	0.802	0.197
M81.85 Other osteoporosis (Pelvic region and thigh)	0.000	0.802	0.197
M81.84 Other osteoporosis (Hand)	0.000	0.802	0.197
M81.83 Other osteoporosis (Forearm)	0.000	0.802	0.197
M81.82 Other osteoporosis (Upper arm)	0.000	0.802	0.197
M81.81 Other osteoporosis (Shoulder region)	0.000	0.802	0.197
M80.98 Unspecified osteoporosis with pathological fracture (Other)	0.000	0.804	0.196
K57.3 Diverticular disease of large intestine without perforation or abscess	0.000	0.804	0.196
M83.3 Adult osteomalacia due to malnutrition	0.000	0.804	0.195
M84.83 Other disorders of continuity of bone (Forearm)	0.000	0.806	0.193
M84.05 Malunion of fracture (Pelvic region and thigh)	0.000	0.807	0.193
M84.11 Nonunion of fracture [pseudarthrosis] (Shoulder region)	0.000	0.809	0.191
M84.37 Stress fracture, not elsewhere classified (Ankle and foot)	0.000	0.809	0.190
M84.13 Nonunion of fracture [pseudarthrosis] (Forearm)	0.000	0.811	0.189
M84.03 Malunion of fracture (Forearm)	0.000	0.812	0.188
M85.49 Solitary bone cyst (Site unspecified)	0.000	0.813	0.187
M85.48 Solitary bone cyst (Other)	0.000	0.813	0.187
M85.44 Solitary bone cyst (Hand)	0.000	0.813	0.187
M85.43 Solitary bone cyst (Forearm)	0.000	0.813	0.187
M85.42 Solitary bone cyst (Upper arm)	0.000	0.813	0.187
M85.41 Solitary bone cyst (Shoulder region)	0.000	0.813	0.187
M85.40 Solitary bone cyst (Multiple sites)	0.000	0.813	0.187
M84.89 Other disorders of continuity of bone (Site unspecified)	0.000	0.813	0.187
M84.88 Other disorders of continuity of bone (Other)	0.000	0.813	0.187
M84.86 Other disorders of continuity of bone (Lower leg)	0.000	0.813	0.187
M84.85 Other disorders of continuity of bone (Pelvic region and thigh)	0.000	0.813	0.187
M84.84 Other disorders of continuity of bone (Hand)	0.000	0.813	0.187
M84.82 Other disorders of continuity of bone (Upper arm)	0.000	0.813	0.187
M84.81 Other disorders of continuity of bone (Shoulder region)	0.000	0.813	0.187
M84.80 Other disorders of continuity of bone (Multiple sites)	0.000	0.813	0.187
M85.47 Solitary bone cyst (Ankle and foot)	0.000	0.818	0.182
M83.80 Other adult osteomalacia (Multiple sites)	0.000	0.819	0.181
M84.26 Delayed union of fracture (Lower leg)	0.000	0.821	0.179
M81.89 Other osteoporosis (Site unspecified)	0.000	0.821	0.178
M84.04 Malunion of fracture (Hand)	0.000	0.821	0.178
M84.09 Malunion of fracture (Site unspecified)	0.000	0.822	0.178
M84.00 Malunion of fracture (Multiple sites)	0.000	0.822	0.178
M82.1 Osteoporosis in endocrine disorders	0.000	0.822	0.177
M84.39 Stress fracture, not elsewhere classified (Site unspecified)	0.000	0.823	0.176
M84.38 Stress fracture, not elsewhere classified (Other)	0.000	0.823	0.176
M84.36 Stress fracture, not elsewhere classified (Lower leg)	0.000	0.823	0.176
M84.35 Stress fracture, not elsewhere classified (Pelvic region and thigh)	0.000	0.823	0.176
M84.34 Stress fracture, not elsewhere classified (Hand)	0.000	0.823	0.176
M84.33 Stress fracture, not elsewhere classified (Forearm)	0.000	0.823	0.176
M84.32 Stress fracture, not elsewhere classified (Upper arm)	0.000	0.823	0.176
M84.31 Stress fracture, not elsewhere classified (Shoulder region)	0.000	0.823	0.176
M84.30 Stress fracture, not elsewhere classified (Multiple sites)	0.000	0.823	0.176
M81.80 Other osteoporosis (Multiple sites)	0.000	0.824	0.176
M81.00 Postmenopausal osteoporosis (Multiple sites)	0.000	0.824	0.176
M84.08 Malunion of fracture (Other)	0.000	0.824	0.175
M85.46 Solitary bone cyst (Lower leg)	0.000	0.825	0.174
M80.00 Postmenopausal osteoporosis with pathological fracture (Multiple sites)	0.000	0.825	0.174
M84.4 Pathological fracture, not elsewhere classified	0.000	0.828	0.172
M80.99 Unspecified osteoporosis with pathological fracture (Site unspecified)	0.000	0.828	0.171
M84.06 Malunion of fracture (Lower leg)	0.000	0.829	0.171
M84.29 Delayed union of fracture (Site unspecified)	0.000	0.830	0.170
M84.28 Delayed union of fracture (Other)	0.000	0.830	0.170
M84.27 Delayed union of fracture (Ankle and foot)	0.000	0.830	0.170
M84.25 Delayed union of fracture (Pelvic region and thigh)	0.000	0.830	0.170
M84.24 Delayed union of fracture (Hand)	0.000	0.830	0.170
M84.23 Delayed union of fracture (Forearm)	0.000	0.830	0.170
M84.22 Delayed union of fracture (Upper arm)	0.000	0.830	0.170
M84.20 Delayed union of fracture (Multiple sites)	0.000	0.830	0.170
M84.99 Disorder of continuity of bone, unspecified (Site unspecified)	0.000	0.833	0.166
M84.98 Disorder of continuity of bone, unspecified (Other)	0.000	0.833	0.166
M84.97 Disorder of continuity of bone, unspecified (Ankle and foot)	0.000	0.833	0.166
M84.96 Disorder of continuity of bone, unspecified (Lower leg)	0.000	0.833	0.166
M84.95 Disorder of continuity of bone, unspecified (Pelvic region and thigh)	0.000	0.833	0.166
M84.94 Disorder of continuity of bone, unspecified (Hand)	0.000	0.833	0.166
M84.93 Disorder of continuity of bone, unspecified (Forearm)	0.000	0.833	0.166
M84.92 Disorder of continuity of bone, unspecified (Upper arm)	0.000	0.833	0.166
M84.91 Disorder of continuity of bone, unspecified (Shoulder region)	0.000	0.833	0.166
M84.90 Disorder of continuity of bone, unspecified (Multiple sites)	0.000	0.833	0.166
M84.21 Delayed union of fracture (Shoulder region)	0.000	0.836	0.164
M83.89 Other adult osteomalacia (Site unspecified)	0.000	0.836	0.163
M83.88 Other adult osteomalacia (Other)	0.000	0.836	0.163
M83.87 Other adult osteomalacia (Ankle and foot)	0.000	0.836	0.163
M83.86 Other adult osteomalacia (Lower leg)	0.000	0.836	0.163
M83.85 Other adult osteomalacia (Pelvic region and thigh)	0.000	0.836	0.163
M83.84 Other adult osteomalacia (Hand)	0.000	0.836	0.163
M83.83 Other adult osteomalacia (Forearm)	0.000	0.836	0.163
M83.82 Other adult osteomalacia (Upper arm)	0.000	0.836	0.163
M83.81 Other adult osteomalacia (Shoulder region)	0.000	0.836	0.163
M85.45 Solitary bone cyst (Pelvic region and thigh)	0.000	0.839	0.161
M84.01 Malunion of fracture (Shoulder region)	0.000	0.844	0.156
M83.09 Puerperal osteomalacia (Site unspecified)	0.000	0.848	0.151
M83.08 Puerperal osteomalacia (Other)	0.000	0.848	0.151
M83.07 Puerperal osteomalacia (Ankle and foot)	0.000	0.848	0.151
M83.06 Puerperal osteomalacia (Lower leg)	0.000	0.848	0.151
M83.05 Puerperal osteomalacia (Pelvic region and thigh)	0.000	0.848	0.151
M83.04 Puerperal osteomalacia (Hand)	0.000	0.848	0.151
M83.03 Puerperal osteomalacia (Forearm)	0.000	0.848	0.151
M83.02 Puerperal osteomalacia (Upper arm)	0.000	0.848	0.151
M83.01 Puerperal osteomalacia (Shoulder region)	0.000	0.848	0.151
M83.00 Puerperal osteomalacia (Multiple sites)	0.000	0.848	0.151
M83.29 Adult osteomalacia due to malabsorption (Site unspecified)	0.000	0.848	0.151
M83.28 Adult osteomalacia due to malabsorption (Other)	0.000	0.848	0.151
M83.27 Adult osteomalacia due to malabsorption (Ankle and foot)	0.000	0.848	0.151
M83.26 Adult osteomalacia due to malabsorption (Lower leg)	0.000	0.848	0.151
M83.25 Adult osteomalacia due to malabsorption (Pelvic region and thigh)	0.000	0.848	0.151
M83.24 Adult osteomalacia due to malabsorption (Hand)	0.000	0.848	0.151
M83.23 Adult osteomalacia due to malabsorption (Forearm)	0.000	0.848	0.151
M83.22 Adult osteomalacia due to malabsorption (Upper arm)	0.000	0.848	0.151
M83.21 Adult osteomalacia due to malabsorption (Shoulder region)	0.000	0.848	0.151
M83.20 Adult osteomalacia due to malabsorption (Multiple sites)	0.000	0.848	0.151
M83.49 Aluminium bone disease (Site unspecified)	0.000	0.848	0.151
M83.48 Aluminium bone disease (Other)	0.000	0.848	0.151
M83.47 Aluminium bone disease (Ankle and foot)	0.000	0.848	0.151
M83.46 Aluminium bone disease (Lower leg)	0.000	0.848	0.151
M83.45 Aluminium bone disease (Pelvic region and thigh)	0.000	0.848	0.151
M83.44 Aluminium bone disease (Hand)	0.000	0.848	0.151
M83.43 Aluminium bone disease (Forearm)	0.000	0.848	0.151
M83.42 Aluminium bone disease (Upper arm)	0.000	0.848	0.151
M83.41 Aluminium bone disease (Shoulder region)	0.000	0.848	0.151
M83.40 Aluminium bone disease (Multiple sites)	0.000	0.848	0.151
M83.59 Other drug-induced osteomalacia in adults (Site unspecified)	0.000	0.848	0.151
M83.58 Other drug-induced osteomalacia in adults (Other)	0.000	0.848	0.151
M83.57 Other drug-induced osteomalacia in adults (Ankle and foot)	0.000	0.848	0.151
M83.56 Other drug-induced osteomalacia in adults (Lower leg)	0.000	0.848	0.151
M83.55 Other drug-induced osteomalacia in adults (Pelvic region and thigh)	0.000	0.848	0.151
M83.54 Other drug-induced osteomalacia in adults (Hand)	0.000	0.848	0.151
M83.53 Other drug-induced osteomalacia in adults (Forearm)	0.000	0.848	0.151
M83.52 Other drug-induced osteomalacia in adults (Upper arm)	0.000	0.848	0.151
M83.51 Other drug-induced osteomalacia in adults (Shoulder region)	0.000	0.848	0.151
M83.50 Other drug-induced osteomalacia in adults (Multiple sites)	0.000	0.848	0.151
M84.19 Nonunion of fracture [pseudarthrosis] (Site unspecified)	0.000	0.849	0.151
M84.10 Nonunion of fracture [pseudarthrosis] (Multiple sites)	0.000	0.849	0.151
M82.09 Osteoporosis in multiple myelomatosis (Site unspecified)	0.000	0.852	0.148
M82.08 Osteoporosis in multiple myelomatosis (Other)	0.000	0.852	0.148
M82.07 Osteoporosis in multiple myelomatosis (Ankle and foot)	0.000	0.852	0.148
M82.06 Osteoporosis in multiple myelomatosis (Lower leg)	0.000	0.852	0.148
M82.05 Osteoporosis in multiple myelomatosis (Pelvic region and thigh)	0.000	0.852	0.148
M82.04 Osteoporosis in multiple myelomatosis (Hand)	0.000	0.852	0.148
M82.03 Osteoporosis in multiple myelomatosis (Forearm)	0.000	0.852	0.148
M82.02 Osteoporosis in multiple myelomatosis (Upper arm)	0.000	0.852	0.148
M82.01 Osteoporosis in multiple myelomatosis (Shoulder region)	0.000	0.852	0.148
M82.00 Osteoporosis in multiple myelomatosis (Multiple sites)	0.000	0.852	0.148
M82.89 Osteoporosis in other diseases classified elsewhere (Site unspecified)	0.000	0.852	0.148
M82.88 Osteoporosis in other diseases classified elsewhere (Other)	0.000	0.852	0.148
M82.87 Osteoporosis in other diseases classified elsewhere (Ankle and foot)	0.000	0.852	0.148
M82.86 Osteoporosis in other diseases classified elsewhere (Lower leg)	0.000	0.852	0.148
M82.85 Osteoporosis in other diseases classified elsewhere (Pelvic region and thigh)	0.000	0.852	0.148
M82.84 Osteoporosis in other diseases classified elsewhere (Hand)	0.000	0.852	0.148
M82.83 Osteoporosis in other diseases classified elsewhere (Forearm)	0.000	0.852	0.148
M82.82 Osteoporosis in other diseases classified elsewhere (Upper arm)	0.000	0.852	0.148
M82.81 Osteoporosis in other diseases classified elsewhere (Shoulder region)	0.000	0.852	0.148
M82.80 Osteoporosis in other diseases classified elsewhere (Multiple sites)	0.000	0.852	0.148
M84.02 Malunion of fracture (Upper arm)	0.000	0.856	0.143
M83.19 Senile osteomalacia (Site unspecified)	0.000	0.858	0.142
M83.18 Senile osteomalacia (Other)	0.000	0.858	0.142
M83.17 Senile osteomalacia (Ankle and foot)	0.000	0.858	0.142
M83.16 Senile osteomalacia (Lower leg)	0.000	0.858	0.142
M83.15 Senile osteomalacia (Pelvic region and thigh)	0.000	0.858	0.142
M83.14 Senile osteomalacia (Hand)	0.000	0.858	0.142
M83.13 Senile osteomalacia (Forearm)	0.000	0.858	0.142
M83.11 Senile osteomalacia (Shoulder region)	0.000	0.858	0.142
M83.10 Senile osteomalacia (Multiple sites)	0.000	0.858	0.142
M83.98 Adult osteomalacia, unspecified (Other)	0.000	0.858	0.141
M83.97 Adult osteomalacia, unspecified (Ankle and foot)	0.000	0.858	0.141
M83.96 Adult osteomalacia, unspecified (Lower leg)	0.000	0.858	0.141
M83.95 Adult osteomalacia, unspecified (Pelvic region and thigh)	0.000	0.858	0.141
M83.94 Adult osteomalacia, unspecified (Hand)	0.000	0.858	0.141
M83.93 Adult osteomalacia, unspecified (Forearm)	0.000	0.858	0.141
M83.92 Adult osteomalacia, unspecified (Upper arm)	0.000	0.858	0.141
M83.91 Adult osteomalacia, unspecified (Shoulder region)	0.000	0.858	0.141
M83.90 Adult osteomalacia, unspecified (Multiple sites)	0.000	0.858	0.141
M83.39 Adult osteomalacia due to malnutrition (Site unspecified)	0.000	0.859	0.140
M83.38 Adult osteomalacia due to malnutrition (Other)	0.000	0.859	0.140
M83.37 Adult osteomalacia due to malnutrition (Ankle and foot)	0.000	0.859	0.140
M83.36 Adult osteomalacia due to malnutrition (Lower leg)	0.000	0.859	0.140
M83.35 Adult osteomalacia due to malnutrition (Pelvic region and thigh)	0.000	0.859	0.140
M83.34 Adult osteomalacia due to malnutrition (Hand)	0.000	0.859	0.140
M83.33 Adult osteomalacia due to malnutrition (Forearm)	0.000	0.859	0.140
M83.32 Adult osteomalacia due to malnutrition (Upper arm)	0.000	0.859	0.140
M83.31 Adult osteomalacia due to malnutrition (Shoulder region)	0.000	0.859	0.140
M84.15 Nonunion of fracture [pseudarthrosis] (Pelvic region and thigh)	0.000	0.860	0.140
M84.17 Nonunion of fracture [pseudarthrosis] (Ankle and foot)	0.000	0.861	0.139
M84.42 Pathological fracture, not elsewhere classified (Upper arm)	0.000	0.867	0.132
M83.12 Senile osteomalacia (Upper arm)	0.000	0.871	0.129
M83.99 Adult osteomalacia, unspecified (Site unspecified)	0.000	0.872	0.128
M84.12 Nonunion of fracture [pseudarthrosis] (Upper arm)	0.000	0.872	0.128
M82.19 Osteoporosis in endocrine disorders (Site unspecified)	0.000	0.872	0.127
M82.18 Osteoporosis in endocrine disorders (Other)	0.000	0.872	0.127
M82.17 Osteoporosis in endocrine disorders (Ankle and foot)	0.000	0.872	0.127
M82.16 Osteoporosis in endocrine disorders (Lower leg)	0.000	0.872	0.127
M82.15 Osteoporosis in endocrine disorders (Pelvic region and thigh)	0.000	0.872	0.127
M82.14 Osteoporosis in endocrine disorders (Hand)	0.000	0.872	0.127
M82.13 Osteoporosis in endocrine disorders (Forearm)	0.000	0.872	0.127
M82.12 Osteoporosis in endocrine disorders (Upper arm)	0.000	0.872	0.127
M84.18 Nonunion of fracture [pseudarthrosis] (Other)	0.000	0.874	0.126
M83.30 Adult osteomalacia due to malnutrition (Multiple sites)	0.000	0.875	0.125
M84.49 Pathological fracture, not elsewhere classified (Site unspecified)	0.000	0.876	0.124
M84.47 Pathological fracture, not elsewhere classified (Ankle and foot)	0.000	0.876	0.124
M84.46 Pathological fracture, not elsewhere classified (Lower leg)	0.000	0.876	0.124
M84.44 Pathological fracture, not elsewhere classified (Hand)	0.000	0.876	0.124
M84.43 Pathological fracture, not elsewhere classified (Forearm)	0.000	0.876	0.124
M82.10 Osteoporosis in endocrine disorders (Multiple sites)	0.000	0.878	0.122
M84.41 Pathological fracture, not elsewhere classified (Shoulder region)	0.000	0.878	0.121
M84.40 Pathological fracture, not elsewhere classified (Multiple sites)	0.000	0.881	0.119
M84.48 Pathological fracture, not elsewhere classified (Other)	0.000	0.893	0.107
M82.11 Osteoporosis in endocrine disorders (Shoulder region)	0.000	0.894	0.106
M84.14 Nonunion of fracture [pseudarthrosis] (Hand)	0.000	0.900	0.100
M84.16 Nonunion of fracture [pseudarthrosis] (Lower leg)	0.000	0.910	0.089
M84.45 Pathological fracture, not elsewhere classified (Pelvic region and thigh)	0.001	0.912	0.087
K63.9 Disease of intestine, unspecified	0.000	0.985	0.015
E04.9 Non-toxic goitre, unspecified	0.014	0.986	0.000
E04.1 Non-toxic single thyroid nodule	0.013	0.987	0.000
K72.9 Hepatic failure, unspecified	0.012	0.988	0.000
O14.9 Preeclampsia, unspecified	0.000	0.988	0.012
E04 Other non-toxic goitre	0.011	0.989	0.000
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria	0.000	0.989	0.011

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations