TreeWAS – Variant ID: rs4740446

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
S22.40 Multiple fractures of ribs (closed)	0.056	0.944	0.000
Y52.4 Angiotensin-converting-enzyme inhibitors	0.050	0.950	0.000
S22.4 Multiple fractures of ribs	0.050	0.950	0.000
Y52 Agents primarily affecting the cardiovascular system	0.047	0.953	0.000
S22 Fracture of rib(s), sternum and thoracic spine	0.046	0.954	0.000
Y52.1 Calcium-channel blockers	0.045	0.955	0.000
Y52.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.044	0.956	0.000
Y52.5 Other antihypertensive drugs, not elsewhere classified	0.043	0.957	0.000
S22.2 Fracture of sternum	0.040	0.960	0.000
S22.0 Fracture of thoracic vertebra	0.039	0.961	0.000
S22.1 Multiple fractures of thoracic spine	0.036	0.964	0.000
S22.5 Flail chest	0.036	0.964	0.000
S22.41 Multiple fractures of ribs (open)	0.036	0.964	0.000
S22.20 Fracture of sternum (closed)	0.036	0.964	0.000
S22.00 Fracture of thoracic vertebra (closed)	0.035	0.965	0.000
Y52.8 Antivaricose drugs, including sclerosing agents	0.034	0.966	0.000
Y52.7 Peripheral vasodilators	0.034	0.966	0.000
Y52.0 Cardiac-stimulant glycosides and drugs of similar action	0.033	0.967	0.000
S22.9 Fracture of bony thorax, part unspecified	0.033	0.967	0.000
S22.8 Fracture of other parts of bony thorax	0.033	0.967	0.000
S22.10 Multiple fractures of thoracic spine (closed)	0.030	0.970	0.000
S22.50 Flail chest (closed)	0.030	0.970	0.000
Y52.9 Other and unspecified agents primarily affecting the cardiovascular system	0.029	0.971	0.000
S22.21 Fracture of sternum (open)	0.029	0.971	0.000
S22.01 Fracture of thoracic vertebra (open)	0.028	0.972	0.000
S22.3 Fracture of rib	0.028	0.972	0.000
Y52.2 Other antidysrhythmic drugs, not elsewhere classified	0.028	0.972	0.000
Y52.3 Coronary vasodilators, not elsewhere classified	0.027	0.973	0.000
S20-S29 Injuries to the thorax	0.027	0.973	0.000
S22.11 Multiple fractures of thoracic spine (open)	0.026	0.974	0.000
S22.51 Flail chest (open)	0.026	0.974	0.000
S27 Injury of other and unspecified intrathoracic organs	0.026	0.974	0.000
S27.2 Traumatic heamopneumothorax	0.024	0.976	0.000
S22.81 Fracture of other parts of bony thorax (open)	0.024	0.976	0.000
S22.80 Fracture of other parts of bony thorax (closed)	0.024	0.976	0.000
S22.91 Fracture of bony thorax, part unspecified (open)	0.024	0.976	0.000
S22.90 Fracture of bony thorax, part unspecified (closed)	0.024	0.976	0.000
S27.20 Traumatic haemopneumothorax (without open wound into thoracic cavity)	0.023	0.977	0.000
M84.11 Nonunion of fracture [pseudarthrosis] (Shoulder region)	0.022	0.978	0.000
S27.0 Traumatic pneumothorax	0.022	0.978	0.000
S21 Open wound of thorax	0.021	0.979	0.000
S24 Injury of nerves and spinal cord at thorax level	0.021	0.979	0.000
S27.8 Injury of other specified intrathoracic organs	0.021	0.979	0.000
M84.1 Nonunion of fracture [pseudarthrosis]	0.021	0.979	0.000
M84.15 Nonunion of fracture [pseudarthrosis] (Pelvic region and thigh)	0.020	0.980	0.000
S22.31 Fracture of rib (open)	0.020	0.980	0.000
M84.17 Nonunion of fracture [pseudarthrosis] (Ankle and foot)	0.020	0.980	0.000
S27.3 Other injuries of lung	0.020	0.980	0.000
S28 Crushing injury of thorax and traumatic amputation of part of thorax	0.019	0.981	0.000
S26 Injury of heart	0.019	0.981	0.000
S25 Injury of blood vessels of thorax	0.019	0.981	0.000
S27.9 Injury of unspecified intrathoracic organ	0.019	0.981	0.000
S27.7 Multiple injuries of intrathoracic organs	0.019	0.981	0.000
S27.6 Injury of pleura	0.019	0.981	0.000
S27.5 Injury of thoracic trachea	0.019	0.981	0.000
S27.4 Injury of bronchus	0.019	0.981	0.000
S27.00 Traumatic pneumothorax (without open wound into thoracic cavity)	0.019	0.981	0.000
S23 Dislocation, sprain and strain of joints and ligaments of thorax	0.018	0.982	0.000
S27.21 Traumatic haemopneumothorax (with open wound into thoracic cavity)	0.018	0.982	0.000
S21.1 Open wound of front wall of thorax	0.018	0.982	0.000
M84.12 Nonunion of fracture [pseudarthrosis] (Upper arm)	0.017	0.983	0.000
S27.1 Traumatic haemothorax	0.017	0.983	0.000
S27.80 Injury of other specified intrathoracic organs (without open wound into thoracic cavity)	0.017	0.983	0.000
S24.1 Other and unspecified injuries of thoracic spinal cord	0.017	0.983	0.000
S27.30 Other injuries of lung (without open wound into thoracic cavity)	0.016	0.984	0.000
S27.01 Traumatic pneumothorax (with open wound into thoracic cavity)	0.015	0.984	0.000
S21.9 Open wound of thorax, part unspecified	0.015	0.985	0.000
S21.8 Open wound of other parts of thorax	0.015	0.985	0.000
S21.7 Multiple open wounds of thoracic wall	0.015	0.985	0.000
S21.0 Open wound of breast	0.015	0.985	0.000
S24.6 Injury of unspecified nerve of thorax	0.015	0.985	0.000
S24.5 Injury of other nerves of thorax	0.015	0.985	0.000
S24.4 Injury of thoracic sympathetic nerves	0.015	0.985	0.000
S24.3 Injury of peripheral nerves of thorax	0.015	0.985	0.000
S24.2 Injury of nerve root of thoracic spine	0.015	0.985	0.000
S24.0 Concussion and oedema of thoracic spinal cord	0.015	0.985	0.000
S27.81 Injury of other specified intrathoracic organs (with open wound into thoracic cavity)	0.015	0.985	0.000
M84.19 Nonunion of fracture [pseudarthrosis] (Site unspecified)	0.015	0.985	0.000
M84.10 Nonunion of fracture [pseudarthrosis] (Multiple sites)	0.015	0.985	0.000
M84.16 Nonunion of fracture [pseudarthrosis] (Lower leg)	0.015	0.985	0.000
S22.30 Fracture of rib (closed)	0.015	0.985	0.000
S27.31 Other injuries of lung (with open wound into thoracic cavity)	0.014	0.985	0.000
S21.2 Open wound of back wall of thorax	0.014	0.986	0.000
S25.9 Injury of unspecified blood vessel of thorax	0.014	0.986	0.000
S25.8 Injury of other blood vessels of thorax	0.014	0.986	0.000
S25.7 Injury of multiple blood vessels of thorax	0.014	0.986	0.000
S25.5 Injury of intercostal blood vessels	0.014	0.986	0.000
S25.4 Injury of pulmonary blood vessels	0.014	0.986	0.000
S25.3 Injury of innominate or subclavian vein	0.014	0.986	0.000
S25.2 Injury of superior vena cava	0.014	0.986	0.000
S25.1 Injury of innominate or subclavian artery	0.014	0.986	0.000
S25.0 Injury of thoracic aorta	0.014	0.986	0.000
S26.9 Injury of heart, unspecified	0.014	0.986	0.000
S26.8 Other injuries of heart	0.014	0.986	0.000
S26.0 Injury of heart with haemopericardium	0.014	0.986	0.000
S28.1 Traumatic amputation of part of thorax	0.014	0.986	0.000
S28.0 Crushed chest	0.014	0.986	0.000
M84.18 Nonunion of fracture [pseudarthrosis] (Other)	0.014	0.986	0.000
S27.41 Injury of bronchus (with open wound into thoracic cavity)	0.014	0.986	0.000
S27.40 Injury of bronchus (without open wound into thoracic cavity)	0.014	0.986	0.000
S27.51 Injury of thoracic trachea (with open wound into thoracic cavity)	0.014	0.986	0.000
S27.50 Injury of thoracic trachea (without open wound into thoracic cavity)	0.014	0.986	0.000
S27.61 Injury of pleura (with open wound into thoracic cavity)	0.014	0.986	0.000
S27.60 Injury of pleura (without open wound into thoracic cavity)	0.014	0.986	0.000
S27.71 Multiple injuries of intrathoracic organs (with open wound into thoracic cavity)	0.014	0.986	0.000
S27.70 Multiple injuries of intrathoracic organs (without open wound into thoracic cavity)	0.014	0.986	0.000
S27.91 Injury of unspecified intrathoracic organ (with open wound into thoracic cavity)	0.014	0.986	0.000
S27.90 Injury of unspecified intrathoracic organ (without open wound into thoracic cavity)	0.014	0.986	0.000
S23.5 Sprain and strain of other and unspecified parts of thorax	0.013	0.987	0.000
S23.3 Sprain and strain of thoracic spine	0.013	0.987	0.000
S23.2 Dislocation of other and unspecified parts of thorax	0.013	0.987	0.000
S23.1 Dislocation of thoracic vertebra	0.013	0.987	0.000
S23.0 Traumatic rupture of thoracic intervertebral disk	0.013	0.987	0.000
M84.14 Nonunion of fracture [pseudarthrosis] (Hand)	0.013	0.987	0.000
S27.11 Traumatic haemothorax (with open wound into thoracic cavity)	0.012	0.987	0.000
S29 Other and unspecified injuries of thorax	0.012	0.988	0.000
S20 Superficial injury of thorax	0.012	0.988	0.000
S23.4 Sprain and strain of ribs and sternum	0.012	0.988	0.000
S27.10 Traumatic haemothorax (without open wound into thoracic cavity)	0.011	0.989	0.000
H92.0 Otalgia	0.011	0.989	0.000
M84.13 Nonunion of fracture [pseudarthrosis] (Forearm)	0.011	0.989	0.000
R52.1 Chronic intractable pain	0.000	0.989	0.011
N75.1 Abscess of Bartholin's gland	0.011	0.989	0.000
S26.01 Injury of heart with haemopericardium (with open wound into thoracic cavity)	0.010	0.990	0.000
S26.00 Injury of heart with haemopericardium (without open wound into thoracic cavity)	0.010	0.990	0.000
S26.81 Other injuries of heart (with open wound into thoracic cavity)	0.010	0.990	0.000
S26.80 Other injuries of heart (without open wound into thoracic cavity)	0.010	0.990	0.000
S26.91 Injury of heart, unspecified (with open wound into thoracic cavity)	0.010	0.990	0.000
S26.90 Injury of heart, unspecified (without open wound into thoracic cavity)	0.010	0.990	0.000
S20.0 Contusion of breast	0.009	0.990	0.000
S29.0 Injury of muscle and tendon at thorax level	0.009	0.991	0.000
S29.7 Multiple injuries of thorax	0.009	0.991	0.000
W07.0 Home	0.000	0.991	0.009
S20.7 Multiple superficial injuries of thorax	0.009	0.991	0.000
S20.4 Other superficial injuries of back wall of thorax	0.009	0.991	0.000
S20.1 Other and unspecified superficial injuries of breast	0.009	0.991	0.000
H92 Otalgia and effusion of ear	0.009	0.991	0.000
N75.0 Cyst of Bartholin's gland	0.008	0.992	0.000
S20.8 Superficial injuries of other and unspecified parts of thorax	0.008	0.992	0.000
N75 Diseases of Bartholin's gland	0.008	0.992	0.000
T31.0 Burns involving less than 10% of body surface	0.000	0.992	0.008
H92.1 Otorrhoea	0.008	0.992	0.000
S20.3 Other superficial injuries of front wall of thorax	0.007	0.993	0.000
S29.8 Other specified injuries of thorax	0.007	0.993	0.000
N75.9 Disease of Bartholin's gland, unspecified	0.007	0.993	0.000
H92.2 Otorrhagia	0.006	0.994	0.000
N75.8 Other diseases of Bartholin's gland	0.006	0.994	0.000
R54 Senility	0.000	0.994	0.006
W07 Fall involving chair	0.000	0.994	0.006
M06.94 Rheumatoid arthritis, unspecified (Hand)	0.006	0.994	0.000
S20.2 Contusion of thorax	0.005	0.994	0.000
S29.9 Unspecified injury of thorax	0.005	0.994	0.000
W07.9 Unspecified place	0.000	0.995	0.005
H91.3 Deaf mutism, not elsewhere classified	0.005	0.995	0.000
I27.9 Pulmonary heart disease, unspecified	0.000	0.995	0.005
W07.5 Trade and service area	0.000	0.995	0.005
F00.9 Dementia in Alzheimer's disease, unspecified	0.000	0.995	0.005
H90-H95 Other disorders of ear	0.005	0.995	0.000
H91 Other hearing loss	0.005	0.995	0.000
S02.10 Fracture of base of skull (closed)	0.005	0.995	0.000
M47.87 Other spondylosis (Lumbosacral region)	0.000	0.995	0.005
Y83.2 Surgical operation with anastomosis, bypass or graft	0.000	0.995	0.005
I70.20 Atherosclerosis of arteries of extremities (without gangrene)	0.000	0.995	0.005
S52.10 Fracture of upper end of radius (closed)	0.005	0.995	0.000
D33.3 Cranial nerves	0.000	0.995	0.005
K55.2 Angiodysplasia of colon	0.005	0.995	0.000
W07.2 School, other institution and public administrative area	0.000	0.995	0.005
W07.8 Other specified place	0.000	0.995	0.005
W07.7 Farm	0.000	0.995	0.005
W07.6 Industrial and construction area	0.000	0.995	0.005
W07.4 Street and highway	0.000	0.995	0.005
W07.3 Sports and athletics area	0.000	0.995	0.005
W07.1 Residential institution	0.000	0.995	0.005
M84 Disorders of continuity of bone	0.004	0.995	0.000
F00 Dementia in Alzheimer's disease	0.000	0.996	0.004
H91.8 Other specified hearing loss	0.004	0.996	0.000
H93 Other disorders of ear, not elsewhere classified	0.004	0.996	0.000
H91.0 Ototoxic hearing loss	0.004	0.996	0.000
T31 Burns classified according to extent of body surface involved	0.000	0.996	0.004
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified	0.004	0.996	0.000
S62.00 Fracture of navicular [scaphoid] bone of hand (closed)	0.004	0.996	0.000
N95.1 Menopausal and female climacteric states	0.000	0.996	0.004
H93.1 Tinnitus	0.004	0.996	0.000
S62.20 Fracture of first metacarpal bone (closed)	0.004	0.996	0.000
F01.9 Vascular dementia, unspecified	0.000	0.996	0.004
H95.0 Recurrent cholesteatoma of postmastoidectomy cavity	0.004	0.996	0.000
H94 Other disorders of ear in diseases classified elsewhere	0.004	0.996	0.000
H91.1 Presbycusis	0.004	0.996	0.000
F00.2 Dementia in Alzheimer's disease, atypical or mixed type	0.000	0.996	0.004
F06.7 Mild cognitive disorder	0.000	0.996	0.004
F01 Vascular dementia	0.000	0.996	0.004
H93.3 Disorders of acoustic nerve	0.004	0.996	0.000
W07.29 Fall involving chair; School, other institution and public administrative area; During unspecified activity	0.000	0.996	0.003
N83.9 Noninflammatory disorder of ovary, Fallopian tube and broad ligament, unspecified	0.000	0.996	0.004
F00.1 Dementia in Alzheimer's disease with late onset	0.000	0.996	0.003
N45.9 Orchitis, epididymitis and epididymo-orchitis without abscess	0.000	0.996	0.004
M84.9 Disorder of continuity of bone, unspecified	0.003	0.996	0.000
N88.9 Noninflammatory disorder of cervix uteri, unspecified	0.004	0.996	0.000
I89.1 Lymphangitis	0.003	0.996	0.000
M84.3 Stress fracture, not elsewhere classified	0.003	0.997	0.000
M84.2 Delayed union of fracture	0.003	0.997	0.000
Z30.5 Surveillance of (intra-uterine) contraceptive device	0.003	0.997	0.000
H93.8 Other specified disorders of ear	0.003	0.997	0.000
F06 Other mental disorders due to brain damage and dysfunction and to physical disease	0.000	0.997	0.003
H91.2 Sudden idiopathic hearing loss	0.003	0.997	0.000
H93.0 Degenerative and vascular disorders of ear	0.003	0.997	0.000
F00-F09 Organic, including symptomatic, mental disorders	0.000	0.997	0.003
T31.9 Burns involving 90% or more of body surface	0.000	0.997	0.003
T31.8 Burns involving 80-89% of body surface	0.000	0.997	0.003
T31.7 Burns involving 70-79% of body surface	0.000	0.997	0.003
T31.6 Burns involving 60-69% of body surface	0.000	0.997	0.003
T31.5 Burns involving 50-59% of body surface	0.000	0.997	0.003
T31.4 Burns involving 40-49% of body surface	0.000	0.997	0.003
T31.3 Burns involving 30-39% of body surface	0.000	0.997	0.003
T31.2 Burns involving 20-29% of body surface	0.000	0.997	0.003
M84.8 Other disorders of continuity of bone	0.003	0.997	0.000
S62.50 Fracture of thumb (closed)	0.003	0.997	0.000
S02.1 Fracture of base of skull	0.003	0.997	0.000
F00.0 Dementia in Alzheimer's disease with early onset	0.000	0.997	0.003
H95.9 Postprocedural disorder of ear and mastoid process, unspecified	0.003	0.997	0.000
S62.0 Fracture of navicular [scaphoid] bone of hand	0.003	0.997	0.000
G44.0 Cluster headache syndrome	0.000	0.997	0.003
M84.4 Pathological fracture, not elsewhere classified	0.003	0.997	0.000
T31.1 Burns involving 10-19% of body surface	0.000	0.997	0.003
S62.2 Fracture of first metacarpal bone	0.003	0.997	0.000
C43.5 Malignant melanoma of trunk	0.003	0.997	0.000
Y44.2 Anticoagulants	0.000	0.997	0.003
H94.8 Other specified disorders of ear in diseases classified elsewhere	0.003	0.997	0.000
H94.0 Acoustic neuritis in infectious and parasitic diseases classified elsewhere	0.003	0.997	0.000
H95.8 Other postprocedural disorders of ear and mastoid process	0.003	0.997	0.000
Y83.9 Surgical procedure, unspecified	0.003	0.997	0.000
I70.2 Atherosclerosis of arteries of the extremities	0.000	0.997	0.003
F07 Personality and behavioural disorders due to brain disease, damage and dysfunction	0.000	0.997	0.003
F01.1 Multi-infarct dementia	0.000	0.997	0.003
G91.1 Obstructive hydrocephalus	0.000	0.997	0.003
M84.22 Delayed union of fracture (Upper arm)	0.003	0.997	0.000
F01.8 Other vascular dementia	0.000	0.997	0.003
F01.3 Mixed cortical and subcortical vascular dementia	0.000	0.997	0.003
F01.2 Subcortical vascular dementia	0.000	0.997	0.003
F01.0 Vascular dementia of acute onset	0.000	0.997	0.003
S62.5 Fracture of thumb	0.003	0.997	0.000
S02.20 Fracture of nasal bones (closed)	0.003	0.997	0.000
H93.9 Disorder of ear, unspecified	0.003	0.997	0.000
K74.0 Hepatic fibrosis	0.003	0.997	0.000
I89.8 Other specified non-infective disorders of lymphatic vessels and lymph nodes	0.003	0.997	0.000
D33.4 Spinal cord	0.000	0.997	0.003
F07.0 Organic personality disorder	0.000	0.997	0.003
O99.2 Endocrine, nutritional and metabolic diseases complicating pregnancy, childbirth and the puerperium	0.003	0.997	0.000
H91.9 Hearing loss, unspecified	0.003	0.997	0.000
H93.2 Other abnormal auditory perceptions	0.003	0.997	0.000
S02.11 Fracture of base of skull (open)	0.003	0.997	0.000
M84.99 Disorder of continuity of bone, unspecified (Site unspecified)	0.003	0.997	0.000
M84.98 Disorder of continuity of bone, unspecified (Other)	0.003	0.997	0.000
M84.97 Disorder of continuity of bone, unspecified (Ankle and foot)	0.003	0.997	0.000
M84.96 Disorder of continuity of bone, unspecified (Lower leg)	0.003	0.997	0.000
M84.95 Disorder of continuity of bone, unspecified (Pelvic region and thigh)	0.003	0.997	0.000
M84.94 Disorder of continuity of bone, unspecified (Hand)	0.003	0.997	0.000
M84.93 Disorder of continuity of bone, unspecified (Forearm)	0.003	0.997	0.000
M84.92 Disorder of continuity of bone, unspecified (Upper arm)	0.003	0.997	0.000
M84.91 Disorder of continuity of bone, unspecified (Shoulder region)	0.003	0.997	0.000
M84.90 Disorder of continuity of bone, unspecified (Multiple sites)	0.003	0.997	0.000
M84.29 Delayed union of fracture (Site unspecified)	0.003	0.997	0.000
M84.28 Delayed union of fracture (Other)	0.003	0.997	0.000
M84.27 Delayed union of fracture (Ankle and foot)	0.003	0.997	0.000
M84.25 Delayed union of fracture (Pelvic region and thigh)	0.003	0.997	0.000
M84.24 Delayed union of fracture (Hand)	0.003	0.997	0.000
M84.23 Delayed union of fracture (Forearm)	0.003	0.997	0.000
M84.21 Delayed union of fracture (Shoulder region)	0.003	0.997	0.000
M84.20 Delayed union of fracture (Multiple sites)	0.003	0.997	0.000
M84.39 Stress fracture, not elsewhere classified (Site unspecified)	0.003	0.997	0.000
M84.38 Stress fracture, not elsewhere classified (Other)	0.003	0.997	0.000
M84.36 Stress fracture, not elsewhere classified (Lower leg)	0.003	0.997	0.000
M84.35 Stress fracture, not elsewhere classified (Pelvic region and thigh)	0.003	0.997	0.000
M84.34 Stress fracture, not elsewhere classified (Hand)	0.003	0.997	0.000
M84.33 Stress fracture, not elsewhere classified (Forearm)	0.003	0.997	0.000
M84.32 Stress fracture, not elsewhere classified (Upper arm)	0.003	0.997	0.000
M84.31 Stress fracture, not elsewhere classified (Shoulder region)	0.003	0.997	0.000
M84.30 Stress fracture, not elsewhere classified (Multiple sites)	0.003	0.997	0.000
M84.87 Other disorders of continuity of bone (Ankle and foot)	0.003	0.997	0.000
F06.2 Organic delusional [schizophrenia-like] disorder	0.000	0.997	0.003
G30.9 Alzheimer's disease, unspecified	0.000	0.997	0.003
F07.2 Postconcussional syndrome	0.000	0.997	0.003
D33 Benign neoplasm of brain and other parts of central nervous system	0.000	0.997	0.003
S42.10 Fracture of scapula (closed)	0.003	0.997	0.000
F06.6 Organic emotionally labile [asthenic] disorder	0.000	0.997	0.003
F06.5 Organic dissociative disorder	0.000	0.997	0.003
F06.4 Organic anxiety disorder	0.000	0.997	0.003
F06.3 Organic mood [affective] disorders	0.000	0.997	0.003
F06.1 Organic catatonic disorder	0.000	0.997	0.003
F06.0 Organic hallucinosis	0.000	0.997	0.003
H95.1 Other disorders following mastoidectomy	0.003	0.997	0.000
N45.0 Orchitis, epididymitis and epididymo-orchitis with abscess	0.000	0.997	0.003
I22.1 Subsequent myocardial infarction of inferior wall	0.000	0.997	0.003
F04 Organic amnesic syndrome, not induced by alcohol and other psychoactive substances	0.000	0.997	0.003
M84.37 Stress fracture, not elsewhere classified (Ankle and foot)	0.002	0.997	0.000
M84.89 Other disorders of continuity of bone (Site unspecified)	0.002	0.997	0.000
M84.88 Other disorders of continuity of bone (Other)	0.002	0.997	0.000
M84.86 Other disorders of continuity of bone (Lower leg)	0.002	0.997	0.000
M84.85 Other disorders of continuity of bone (Pelvic region and thigh)	0.002	0.997	0.000
M84.84 Other disorders of continuity of bone (Hand)	0.002	0.997	0.000
M84.82 Other disorders of continuity of bone (Upper arm)	0.002	0.997	0.000
M84.81 Other disorders of continuity of bone (Shoulder region)	0.002	0.997	0.000
M84.80 Other disorders of continuity of bone (Multiple sites)	0.002	0.997	0.000
I70.21 Atherosclerosis of arteries of extremities (with gangrene)	0.000	0.997	0.003
M54.12 Radiculopathy (Cervical region)	0.003	0.997	0.000
M84.42 Pathological fracture, not elsewhere classified (Upper arm)	0.002	0.997	0.000
M84.41 Pathological fracture, not elsewhere classified (Shoulder region)	0.002	0.997	0.000
F06.8 Other specified mental disorders due to brain damage and dysfunction and to physical disease	0.000	0.997	0.002
F09 Unspecified organic or symptomatic mental disorder	0.000	0.997	0.002
M84.49 Pathological fracture, not elsewhere classified (Site unspecified)	0.002	0.997	0.000
M84.47 Pathological fracture, not elsewhere classified (Ankle and foot)	0.002	0.997	0.000
M84.46 Pathological fracture, not elsewhere classified (Lower leg)	0.002	0.997	0.000
M84.44 Pathological fracture, not elsewhere classified (Hand)	0.002	0.997	0.000
M84.43 Pathological fracture, not elsewhere classified (Forearm)	0.002	0.997	0.000
S62.01 Fracture of navicular [scaphoid] bone of hand (open)	0.002	0.997	0.000
M84.40 Pathological fracture, not elsewhere classified (Multiple sites)	0.002	0.997	0.000
S62.21 Fracture of first metacarpal bone (open)	0.002	0.997	0.000
H80.9 Otosclerosis, unspecified	0.000	0.997	0.003
F32.2 Severe depressive episode without psychotic symptoms	0.000	0.997	0.003
I22.8 Subsequent myocardial infarction of other sites	0.000	0.997	0.003
S06.40 Epidural haemorrhage (without open intracranial wound)	0.002	0.997	0.000
S72.30 Fracture of shaft of femur (closed)	0.002	0.997	0.000
F07.8 Other organic personality and behavioural disorders due to brain disease, damage and dysfunction	0.000	0.997	0.002
F07.1 Postencephalitic syndrome	0.000	0.997	0.002
S52.1 Fracture of upper end of radius	0.002	0.997	0.000
S62 Fracture at wrist and hand level	0.003	0.997	0.000
M84.45 Pathological fracture, not elsewhere classified (Pelvic region and thigh)	0.002	0.998	0.000
S62.40 Multiple fractures of metacarpal bones (closed)	0.002	0.998	0.000
F06.9 Unspecified mental disorder due to brain damage and dysfunction and to physical disease	0.000	0.998	0.002
J82 Pulmonary eosinophilia, not elsewhere classified	0.002	0.998	0.000
N45 Orchitis and epididymitis	0.000	0.998	0.002
S62.51 Fracture of thumb (open)	0.002	0.998	0.000
S62.4 Multiple fractures of metacarpal bones	0.002	0.998	0.000
W19.3 Sports and athletics area	0.002	0.998	0.000
M84.83 Other disorders of continuity of bone (Forearm)	0.002	0.998	0.000
J34.1 Cyst and mucocele of nose and nasal sinus	0.002	0.998	0.000
F03 Unspecified dementia	0.000	0.998	0.002
M23.83 Other internal derangements of knee (Medial collateral ligament or Other and unspecified medial meniscus)	0.000	0.998	0.002
M84.26 Delayed union of fracture (Lower leg)	0.002	0.998	0.000
M47.84 Other spondylosis (Thoracic region)	0.000	0.998	0.002
N83.1 Corpus luteum cyst	0.002	0.998	0.000
M23.81 Other internal derangements of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.000	0.998	0.002
J11.1 Influenza with other respiratory manifestations, virus not identified	0.002	0.998	0.000
S82.00 Fracture of patella (closed)	0.002	0.998	0.000
F07.9 Unspecified organic personality and behavioural disorder due to brain disease, damage and dysfunction	0.000	0.998	0.002
M84.48 Pathological fracture, not elsewhere classified (Other)	0.002	0.998	0.000
K55.0 Acute vascular disorders of intestine	0.002	0.998	0.000
M47.8 Other spondylosis	0.000	0.998	0.002
R82.8 Abnormal findings on cytological and histological examination of urine	0.000	0.998	0.002
M47.88 Other spondylosis (Sacral and sacrococcygeal region)	0.000	0.998	0.002
D33.9 Central nervous system, unspecified	0.000	0.998	0.002
D33.7 Other specified parts of central nervous system	0.000	0.998	0.002
D33.1 Brain, infratentorial	0.000	0.998	0.002
T84.6 Infection and inflammatory reaction due to internal fixation device [any site]	0.002	0.998	0.000
R07.3 Other chest pain	0.002	0.998	0.000
R49.8 Other and unspecified voice disturbances	0.002	0.998	0.000
S02.2 Fracture of nasal bones	0.002	0.998	0.000
K55 Vascular disorders of intestine	0.002	0.998	0.000
S02.90 Fracture of skull and facial bones, part unspecified (closed)	0.002	0.998	0.000
D33.0 Brain, supratentorial	0.000	0.998	0.002
M47.89 Other spondylosis (Site unspecified)	0.000	0.998	0.002
G44 Other headache syndromes	0.000	0.998	0.002
M84.0 Malunion of fracture	0.002	0.998	0.000
G44.2 Tension-type headache	0.000	0.998	0.002
I22.0 Subsequent myocardial infarction of anterior wall	0.000	0.998	0.002
F02 Dementia in other diseases classified elsewhere	0.000	0.998	0.002
G44.4 Drug-induced headache, not elsewhere classified	0.000	0.998	0.002
S52.11 Fracture of upper end of radius (open)	0.002	0.998	0.000
S62.41 Multiple fractures of metacarpal bones (open)	0.002	0.998	0.000
F05 Delirium, not induced by alcohol and other psychoactive substances	0.000	0.998	0.002
I89 Other non-infective disorders of lymphatic vessels and lymph nodes	0.002	0.998	0.000
I22 Subsequent myocardial infarction	0.000	0.998	0.002
M84.07 Malunion of fracture (Ankle and foot)	0.002	0.998	0.000
D33.2 Brain, unspecified	0.000	0.998	0.002
G44.8 Other specified headache syndromes	0.000	0.998	0.002
M47.86 Other spondylosis (Lumbar region)	0.000	0.998	0.002
O67.9 Intrapartum haemorrhage, unspecified	0.002	0.998	0.000
V48.4 Person injured while boarding or alighting	0.000	0.998	0.002
A04.7 Enterocolitis due to Clostridium difficile	0.002	0.998	0.000
G91.9 Hydrocephalus, unspecified	0.000	0.998	0.002
S02.9 Fracture of skull and facial bones, part unspecified	0.002	0.998	0.000
T90.2 Sequelae of fracture of skull and facial bones	0.000	0.998	0.002
W55.0 Home	0.000	0.998	0.002
M47.81 Other spondylosis (Occipito-atlanto-axial region)	0.000	0.998	0.002
A04.5 Campylobacter enteritis	0.002	0.998	0.000
S19.9 Unspecified injury of neck	0.000	0.998	0.002
M76.67 Achilles tendinitis (Ankle and foot)	0.002	0.998	0.000
M84.06 Malunion of fracture (Lower leg)	0.002	0.998	0.000
M23.8 Other internal derangements of knee	0.000	0.998	0.002
N70.0 Acute salpingitis and oophoritis	0.000	0.998	0.002
G91.8 Other hydrocephalus	0.000	0.998	0.002
S62.1 Fracture of other carpal bone(s)	0.002	0.998	0.000
M23.82 Other internal derangements of knee (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.000	0.998	0.002
M84.02 Malunion of fracture (Upper arm)	0.002	0.998	0.000
K55.1 Chronic vascular disorders of intestine	0.002	0.998	0.000
N70.9 Salpingitis and oophoritis, unspecified	0.000	0.998	0.002
M47.83 Other spondylosis (Cervicothoracic region)	0.000	0.998	0.002
M80.90 Unspecified osteoporosis with pathological fracture (Multiple sites)	0.000	0.998	0.002
S02.21 Fracture of nasal bones (open)	0.002	0.998	0.000
F05.0 Delirium not superimposed on dementia, so described	0.000	0.998	0.002
M84.09 Malunion of fracture (Site unspecified)	0.002	0.998	0.000
M84.08 Malunion of fracture (Other)	0.002	0.998	0.000
M84.00 Malunion of fracture (Multiple sites)	0.002	0.998	0.000
C16.9 Stomach, unspecified	0.002	0.998	0.000
S02.30 Fracture of orbital floor (closed)	0.002	0.998	0.000
J38.0 Paralysis of vocal cords and larynx	0.002	0.998	0.000
K22.0 Achalasia of cardia	0.002	0.998	0.000
F02.4 Dementia in human immunodeficiency virus [HIV] disease	0.000	0.998	0.002
F02.2 Dementia in Huntington's disease	0.000	0.998	0.002
F02.1 Dementia in Creutzfeldt-Jakob disease	0.000	0.998	0.002
I82.2 Embolism and thrombosis of vena cava	0.002	0.998	0.000
K14.9 Disease of tongue, unspecified	0.000	0.998	0.002
S62.7 Multiple fractures of fingers	0.002	0.998	0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.000	0.998	0.002
C67.4 Posterior wall of bladder	0.000	0.998	0.002
G91 Hydrocephalus	0.000	0.998	0.002
G44.3 Chronic posttraumatic headache	0.000	0.998	0.002
I82.9 Embolism and thrombosis of unspecified vein	0.002	0.998	0.000
R87.7 Abnormal histological findings	0.002	0.998	0.000
S02.3 Fracture of orbital floor	0.002	0.998	0.000
M77.57 Other enthesopathy of foot-Ankle/Foot	0.002	0.998	0.000
F02.3 Dementia in Parkinson's disease	0.000	0.998	0.002
H90.7 Mixed conductive and sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side	0.002	0.998	0.000
M13.00 Polyarthritis, unspecified (Multiple sites)	0.000	0.998	0.002
M62.89 Other specified disorders of muscle (Site unspecified)	0.002	0.998	0.000
C90.2 Plasmacytoma, extramedullary	0.000	0.998	0.002
S02 Fracture of skull and facial bones	0.002	0.998	0.000
M23.89 Other internal derangements of knee (Unspecified ligament or Unspecified meniscus)	0.000	0.998	0.002
C83.3 Large cell (diffuse)	0.000	0.998	0.002
H90.1 Conductive hearing loss, unilateral with unrestricted hearing on the contralateral side	0.002	0.998	0.000
H90 Conductive and sensorineural hearing loss	0.002	0.998	0.000
S06.4 Epidural haemorrhage	0.002	0.998	0.000
S02.91 Fracture of skull and facial bones, part unspecified (open)	0.001	0.998	0.000
I49.0 Ventricular fibrillation and flutter	0.002	0.998	0.000
O99.4 Diseases of the circulatory system complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
M25.46 Effusion of joint (Lower leg)	0.000	0.998	0.002
S82.01 Fracture of patella (open)	0.002	0.998	0.000
I97.8 Other postprocedural disorders of circulatory system, not elsewhere classified	0.000	0.998	0.002
S62.6 Fracture of other finger	0.002	0.998	0.000
G30 Alzheimer's disease	0.000	0.998	0.002
M23.87 Other internal derangements of knee (Capsular ligament)	0.000	0.998	0.001
M23.85 Other internal derangements of knee (Posterior horn of lateral meniscus)	0.000	0.998	0.001
M23.84 Other internal derangements of knee (Lateral collateral ligament or Anterior horn of lateral meniscus)	0.000	0.998	0.002
S62.11 Fracture of other carpal bone(s) (open)	0.001	0.998	0.000
S82.40 Fracture of fibula alone (closed)	0.002	0.998	0.000
K55.8 Other vascular disorders of intestine	0.002	0.998	0.000
S62.8 Fracture of other and unspecified parts of wrist and hand	0.002	0.998	0.000
G70.0 Myasthenia gravis	0.002	0.998	0.000
I60.2 Subarachnoid haemorrhage from anterior communicating artery	0.000	0.998	0.002
M84.04 Malunion of fracture (Hand)	0.001	0.998	0.000
F02.0 Dementia in Pick's disease	0.000	0.998	0.001
G44.1 Vascular headache, not elsewhere classified	0.000	0.998	0.001
I89.9 Non-infective disorder of lymphatic vessels and lymph nodes, unspecified	0.001	0.998	0.000
S62.71 Multiple fractures of fingers (open)	0.001	0.998	0.000
H02.1 Ectropion of eyelid	0.000	0.998	0.002
S42.1 Fracture of scapula	0.002	0.998	0.000
X12.0 Home	0.000	0.998	0.002
C54.1 Endometrium	0.000	0.998	0.002
T30 Burn and corrosion, body region unspecified	0.000	0.998	0.001
M76.66 Achilles tendinitis (Lower leg)	0.001	0.998	0.000
S12.10 Fracture of second cervical vertebra (closed)	0.002	0.998	0.000
S42.40 Fracture of lower end of humerus (closed)	0.002	0.998	0.000
F05.8 Other delirium	0.000	0.998	0.001
M47.85 Other spondylosis (Thoracolumbar region)	0.000	0.998	0.001
S02.31 Fracture of orbital floor (open)	0.001	0.998	0.000
H90.0 Conductive hearing loss, bilateral	0.001	0.998	0.000
M76.6 Achilles tendinitis	0.001	0.998	0.000
S82.0 Fracture of patella	0.002	0.998	0.000
T32 Corrosions classified according to extent of body surface involved	0.000	0.998	0.001
T29 Burns and corrosions of multiple body regions	0.000	0.998	0.001
C80.0 Malignant neoplasm, primary site unknown, so stated	0.000	0.998	0.002
M84.05 Malunion of fracture (Pelvic region and thigh)	0.001	0.998	0.000
C16.6 Greater curvature of stomach, unspecified	0.001	0.998	0.000
C90.0 Multiple myeloma	0.000	0.998	0.002
Y57.9 Drug or medicament, unspecified	0.001	0.998	0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
M65.97 Synovitis and tenosynovitis, unspecified (Ankle and foot)	0.000	0.999	0.001
G30.1 Alzheimer's disease with late onset	0.000	0.999	0.001
M62.88 Other specified disorders of muscle (Other)	0.001	0.999	0.000
M84.01 Malunion of fracture (Shoulder region)	0.001	0.999	0.000
S06.41 Epidural haemorrhage (with open intracranial wound)	0.001	0.999	0.000
F05.1 Delirium superimposed on dementia	0.000	0.999	0.001
G30.8 Other Alzheimer's disease	0.000	0.999	0.001
O99.3 Mental disorders and diseases of the nervous system complicating pregnancy, childbirth and the puerperium	0.001	0.999	0.000
M76.86 Other enthesopathies of lower limb, excluding foot (Lower leg)	0.001	0.999	0.000
S62.81 Fracture of other and unspecified parts of wrist and hand (open)	0.001	0.999	0.000
D48.5 Skin	0.000	0.999	0.001
S62.10 Fracture of other carpal bone(s) (closed)	0.001	0.999	0.000
C16.2 Body of stomach	0.001	0.999	0.000
E80.4 Gilbert's syndrome	0.001	0.999	0.000
G30.0 Alzheimer's disease with early onset	0.000	0.999	0.001
O99.7 Diseases of the skin and subcutaneous tissue complicating pregnancy, childbirth and the puerperium	0.001	0.999	0.000
S42.11 Fracture of scapula (open)	0.001	0.999	0.000
F02.8 Dementia in other specified diseases classified elsewhere	0.000	0.999	0.001
G91.0 Communicating hydrocephalus	0.000	0.999	0.001
M95.0 Acquired deformity of nose	0.000	0.999	0.001
O99.5 Diseases of the respiratory system complicating pregnancy, childbirth and the puerperium	0.001	0.999	0.000
S72.3 Fracture of shaft of femur	0.001	0.999	0.000
T20.1 Burn of first degree of head and neck	0.000	0.999	0.001
M25.42 Effusion of joint (Upper arm)	0.000	0.999	0.001

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations