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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs4750316
log Bayes Factor = <0.0001
Chromosome 10   position 6,393,260  (GRCh37) Explore rs4750316 on Ensembl!
Variant rs4750316 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E03.9 Hypothyroidism, unspecified
0.054 0.946 0.000
E03 Other hypothyroidism
0.027 0.973 0.000
E27.4 Other and unspecified adrenocortical insufficiency
0.025 0.975 0.000
E27 Other disorders of adrenal gland
0.023 0.977 0.000
E27.1 Primary adrenocortical insufficiency
0.021 0.979 0.000
Z01.6 Radiological examination, not elsewhere classified
0.000 0.979 0.021
E20-E35 Disorders of other endocrine glands
0.020 0.980 0.000
E00-E07 Disorders of thyroid gland
0.020 0.980 0.000
E03.5 Myxoedema coma
0.019 0.981 0.000
E03.4 Atrophy of thyroid (acquired)
0.019 0.981 0.000
E03.3 Postinfectious hypothyroidism
0.019 0.981 0.000
E03.0 Congenital hypothyroidism with diffuse goitre
0.019 0.981 0.000
E27.3 Drug-induced adrenocortical insufficiency
0.019 0.981 0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.018 0.982 0.000
E05.9 Thyrotoxicosis, unspecified
0.018 0.982 0.000
E07 Other disorders of thyroid
0.018 0.982 0.000
E27.8 Other specified disorders of adrenal gland
0.018 0.982 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.018 0.982 0.000
E27.5 Adrenomedullary hyperfunction
0.017 0.983 0.000
E27.0 Other adrenocortical overactivity
0.017 0.983 0.000
E34 Other endocrine disorders
0.017 0.983 0.000
E27.2 Addisonian crisis
0.017 0.983 0.000
E07.9 Disorder of thyroid, unspecified
0.016 0.984 0.000
E26 Hyperaldosteronism
0.016 0.984 0.000
E03.1 Congenital hypothyroidism without goitre
0.016 0.984 0.000
E34.9 Endocrine disorder, unspecified
0.016 0.984 0.000
E32 Diseases of thymus
0.015 0.985 0.000
E20 Hypoparathyroidism
0.015 0.985 0.000
E29 Testicular dysfunction
0.015 0.985 0.000
E03.8 Other specified hypothyroidism
0.015 0.985 0.000
E23 Hypofunction and other disorders of pituitary gland
0.015 0.985 0.000
E31 Polyglandular dysfunction
0.014 0.985 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.014 0.985 0.000
E28 Ovarian dysfunction
0.014 0.986 0.000
E07.8 Other specified disorders of thyroid
0.014 0.986 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.014 0.986 0.000
E30 Disorders of puberty, not elsewhere classified
0.014 0.986 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.014 0.986 0.000
E00 Congenital iodine-deficiency syndrome
0.014 0.986 0.000
E22 Hyperfunction of pituitary gland
0.014 0.986 0.000
E27.9 Disorder of adrenal gland, unspecified
0.014 0.986 0.000
E25 Adrenogenital disorders
0.014 0.986 0.000
E14.3 With ophthalmic complications
0.014 0.986 0.000
E34.8 Other specified endocrine disorders
0.013 0.987 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.013 0.987 0.000
E07.1 Dyshormogenetic goitre
0.013 0.987 0.000
E07.0 Hypersecretion of calcitonin
0.013 0.987 0.000
E05.0 Thyrotoxicosis with diffuse goitre
0.013 0.987 0.000
E26.0 Primary hyperaldosteronism
0.013 0.987 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.013 0.987 0.000
E05.5 Thyroid crisis or storm
0.013 0.987 0.000
E05.4 Thyrotoxicosis factitia
0.013 0.987 0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.013 0.987 0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.013 0.987 0.000
Z01 Other special examinations and investigations of persons without complaint or reported diagnosis
0.000 0.987 0.013
E23.2 Diabetes insipidus
0.013 0.987 0.000
E34.5 Androgen resistance syndrome
0.012 0.987 0.000
E34.4 Constitutional tall stature
0.012 0.987 0.000
E34.2 Ectopic hormone secretion, not elsewhere classified
0.012 0.987 0.000
E34.1 Other hypersecretion of intestinal hormones
0.012 0.987 0.000
I34.0 Mitral (valve) insufficiency
0.013 0.987 0.000
E26.9 Hyperaldosteronism, unspecified
0.012 0.988 0.000
E34.0 Carcinoid syndrome
0.012 0.988 0.000
E20.9 Hypoparathyroidism, unspecified
0.012 0.988 0.000
E29.1 Testicular hypofunction
0.012 0.988 0.000
E26.8 Other hyperaldosteronism
0.012 0.988 0.000
E26.1 Secondary hyperaldosteronism
0.012 0.988 0.000
E10-E14 Diabetes mellitus
0.012 0.988 0.000
E32.9 Disease of thymus, unspecified
0.011 0.988 0.000
E32.8 Other diseases of thymus
0.011 0.988 0.000
E34.3 Short stature, not elsewhere classified
0.011 0.988 0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.011 0.989 0.000
E28.3 Primary ovarian failure
0.011 0.989 0.000
E32.1 Abscess of thymus
0.011 0.989 0.000
E32.0 Persistent hyperplasia of thymus
0.011 0.989 0.000
E20.1 Pseudohypoparathyroidism
0.011 0.989 0.000
E20.8 Other hypoparathyroidism
0.011 0.989 0.000
E20.0 Idiopathic hypoparathyroidism
0.011 0.989 0.000
E29.9 Testicular dysfunction, unspecified
0.011 0.989 0.000
E29.8 Other testicular dysfunction
0.011 0.989 0.000
E29.0 Testicular hyperfunction
0.011 0.989 0.000
E14 Unspecified diabetes mellitus
0.011 0.989 0.000
Z01.5 Diagnostic skin and sensitisation tests
0.000 0.989 0.011
I34.1 Mitral (valve) prolapse
0.011 0.989 0.000
E23.7 Disorder of pituitary gland, unspecified
0.011 0.989 0.000
E05.8 Other thyrotoxicosis
0.011 0.989 0.000
E31.0 Autoimmune polyglandular failure
0.011 0.989 0.000
I34 Nonrheumatic mitral valve disorders
0.011 0.989 0.000
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.011 0.989 0.000
Z01.9 Special examination, unspecified
0.000 0.989 0.011
E22.0 Acromegaly and pituitary gigantism
0.011 0.989 0.000
E23.1 Drug-induced hypopituitarism
0.011 0.989 0.000
E21.5 Disorder of parathyroid gland, unspecified
0.011 0.989 0.000
E31.9 Polyglandular dysfunction, unspecified
0.010 0.989 0.000
E31.8 Other polyglandular dysfunction
0.010 0.989 0.000
E31.1 Polyglandular hyperfunction
0.010 0.989 0.000
Z01.2 Dental examination
0.000 0.989 0.011
E28.9 Ovarian dysfunction, unspecified
0.010 0.989 0.000
E28.8 Other ovarian dysfunction
0.010 0.989 0.000
E28.1 Androgen excess
0.010 0.989 0.000
E28.0 Oestrogen excess
0.010 0.989 0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.011 0.989 0.000
E22.9 Hyperfunction of pituitary gland, unspecified
0.010 0.989 0.000
E30.9 Disorder of puberty, unspecified
0.010 0.989 0.000
E30.8 Other disorders of puberty
0.010 0.989 0.000
E30.1 Precocious puberty
0.010 0.989 0.000
E30.0 Delayed puberty
0.010 0.989 0.000
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.010 0.989 0.000
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.010 0.989 0.000
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.010 0.989 0.000
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.010 0.989 0.000
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.010 0.989 0.000
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.010 0.989 0.000
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.010 0.989 0.000
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.010 0.989 0.000
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.010 0.989 0.000
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.010 0.989 0.000
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.010 0.989 0.000
E21.4 Other specified disorders of parathyroid gland
0.010 0.990 0.000
E22.8 Other hyperfunction of pituitary gland
0.010 0.990 0.000
E25.9 Adrenogenital disorder, unspecified
0.010 0.990 0.000
E25.8 Other adrenogenital disorders
0.010 0.990 0.000
E23.6 Other disorders of pituitary gland
0.010 0.990 0.000
E06 Thyroiditis
0.010 0.990 0.000
Z01.4 Gynaecological examination (general)(routine)
0.000 0.990 0.010
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.010 0.990 0.000
E24 Cushing's syndrome
0.010 0.990 0.000
E28.2 Polycystic ovarian syndrome
0.010 0.990 0.000
Z01.3 Examination of blood pressure
0.000 0.990 0.010
Z01.1 Examination of ears and hearing
0.000 0.990 0.009
E21.2 Other hyperparathyroidism
0.009 0.991 0.000
I34.9 Nonrheumatic mitral valve disorder, unspecified
0.009 0.991 0.000
E10 Insulin-dependent diabetes mellitus
0.009 0.991 0.000
Z01.0 Examination of eyes and vision
0.000 0.991 0.009
E14.2 Withrenal complications
0.009 0.991 0.000
E21.3 Hyperparathyroidism, unspecified
0.009 0.991 0.000
E22.1 Hyperprolactinaemia
0.009 0.991 0.000
E12 Malnutrition-related diabetes mellitus
0.008 0.991 0.000
I34.2 Nonrheumatic mitral (valve) stenosis
0.008 0.992 0.000
E11 Non-insulin-dependent diabetes mellitus
0.008 0.992 0.000
E14.6 With other specified complications
0.008 0.992 0.000
E10.9 Without complications
0.008 0.992 0.000
E14.7 With multiple complications
0.008 0.992 0.000
E06.5 Other chronic thyroiditis
0.008 0.992 0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.008 0.992 0.000
E40-E46 Malnutrition
0.008 0.992 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.008 0.992 0.000
E10.8 With unspecified complications
0.008 0.992 0.000
R73.9 Hyperglycaemia, unspecified
0.008 0.992 0.000
E10.2 With renal complications
0.008 0.992 0.000
E11.1 With ketoacidosis
0.008 0.992 0.000
E11.8 With unspecified complications
0.008 0.992 0.000
E23.0 Hypopituitarism
0.008 0.992 0.000
E06.4 Drug-induced thyroiditis
0.007 0.992 0.000
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.007 0.992 0.000
E06.0 Acute thyroiditis
0.007 0.992 0.000
T83.1 Mechanical complication of other urinary devices and implants
0.000 0.992 0.008
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.007 0.993 0.000
E24.3 Ectopic ACTH syndrome
0.007 0.993 0.000
E24.1 Nelson's syndrome
0.007 0.993 0.000
E14.0 With coma
0.007 0.993 0.000
E14.1 With ketoacidosis
0.007 0.993 0.000
E13 Other specified diabetes mellitus
0.007 0.993 0.000
S06.20 Diffuse brain injury (without open intracranial wound)
0.000 0.993 0.007
E24.8 Other Cushing's syndrome
0.007 0.993 0.000
E24.2 Drug-induced Cushing's syndrome
0.007 0.993 0.000
E06.1 Subacute thyroiditis
0.007 0.993 0.000
E10.5 With peripheral circulatory complications
0.007 0.993 0.000
E14.5 With peripheral circulatory complications
0.007 0.993 0.000
E14.4 With neurological complications
0.007 0.993 0.000
Z01.7 Laboratory examination
0.000 0.993 0.007
M87.95 Osteonecrosis, unspecified (Pelvic region and thigh)
0.007 0.993 0.000
E11.6 With other specified complications
0.007 0.993 0.000
Z01.8 Other specified special examinations
0.000 0.993 0.007
I34.8 Other nonrheumatic mitral valve disorders
0.007 0.993 0.000
E14.8 With unspecified complications
0.007 0.993 0.000
S06.40 Epidural haemorrhage (without open intracranial wound)
0.000 0.993 0.007
E11.4 With neurological complications
0.007 0.993 0.000
E24.0 Pituitary-dependent Cushing's disease
0.006 0.993 0.000
S06.2 Diffuse brain injury
0.000 0.993 0.007
E10.7 With multiple complications
0.007 0.993 0.000
E10.4 With neurological complications
0.007 0.993 0.000
E10.3 With ophthalmic complications
0.007 0.993 0.000
E12.9 Without complications
0.006 0.994 0.000
E12.8 With unspecified complications
0.006 0.994 0.000
E12.7 With multiple complications
0.006 0.994 0.000
E12.6 With other specified complications
0.006 0.994 0.000
E12.5 With peripheral circulatory complications
0.006 0.994 0.000
E12.4 With neurological complications
0.006 0.994 0.000
E12.3 With ophthalmic complications
0.006 0.994 0.000
E12.2 With renal complications
0.006 0.994 0.000
E12.1 With ketoacidosis
0.006 0.994 0.000
E12.0 With coma
0.006 0.994 0.000
E14.9 Without complications
0.006 0.994 0.000
S06.4 Epidural haemorrhage
0.000 0.994 0.006
S06 Intracranial injury
0.000 0.994 0.006
E10.1 With ketoacidosis
0.006 0.994 0.000
E10.0 With coma
0.006 0.994 0.000
E50-E64 Other nutritional deficiencies
0.006 0.994 0.000
E44 Protein-energy malnutrition of moderate and mild degree
0.006 0.994 0.000
E45 Retarded development following protein-energy malnutrition
0.006 0.994 0.000
E43 Unspecified severe protein-energy malnutrition
0.006 0.994 0.000
E42 Marasmic kwashiorkor
0.006 0.994 0.000
E41 Nutritional marasmus
0.006 0.994 0.000
E40 Kwashiorkor
0.006 0.994 0.000
E15 Nondiabetic hypoglycaemic coma
0.006 0.994 0.000
S06.3 Focal brain injury
0.000 0.994 0.006
E11.7 With multiple complications
0.006 0.994 0.000
S06.30 Focal brain injury (without open intracranial wound)
0.000 0.994 0.006
E10.6 With other specified complications
0.006 0.994 0.000
S06.5 Traumatic subdural haemorrhage
0.000 0.994 0.006
E06.9 Thyroiditis, unspecified
0.006 0.994 0.000
E11.3 With ophthalmic complications
0.006 0.994 0.000
E11.0 With coma
0.006 0.994 0.000
Z90.2 Acquired absence of lung [part of]
0.000 0.994 0.006
E13.3 With ophthalmic complications
0.006 0.994 0.000
N30.2 Other chronic cystitis
0.000 0.994 0.006
S06.50 Traumatic subdural haemorrhage (without open intracranial wound)
0.000 0.994 0.006
E06.3 Autoimmune thyroiditis
0.005 0.994 0.000
E13.8 With unspecified complications
0.005 0.994 0.000
E13.7 With multiple complications
0.005 0.994 0.000
E13.6 With other specified complications
0.005 0.994 0.000
E13.5 With peripheral circulatory complications
0.005 0.994 0.000
E13.4 With neurological complications
0.005 0.994 0.000
E13.2 With renal complications
0.005 0.994 0.000
E13.1 With ketoacidosis
0.005 0.994 0.000
E13.0 With coma
0.005 0.994 0.000
E24.9 Cushing's syndrome, unspecified
0.005 0.994 0.000
C71.9 Brain, unspecified
0.005 0.995 0.000
C71.1 Frontal lobe
0.005 0.995 0.000
E11.2 With renal complications
0.005 0.995 0.000
E65-E68 Obesity and other hyperalimentation
0.005 0.995 0.000
S06.21 Diffuse brain injury (with open intracranial wound)
0.000 0.995 0.005
S06.1 Traumatic cerebral oedema
0.000 0.995 0.005
S06.41 Epidural haemorrhage (with open intracranial wound)
0.000 0.995 0.005
S06.7 Intracranial injury with prolonged coma
0.000 0.995 0.005
E56 Other vitamin deficiencies
0.005 0.995 0.000
C71 Malignant neoplasm of brain
0.005 0.995 0.000
S06.0 Concussion
0.000 0.995 0.005
S02.10 Fracture of base of skull (closed)
0.000 0.995 0.005
D51.9 Vitamin B12 deficiency anaemia, unspecified
0.005 0.995 0.000
S06.6 Traumatic subarachnoid haemorrhage
0.000 0.995 0.005
E64 Sequelae of malnutrition and other nutritional deficiencies
0.004 0.995 0.000
E50 Vitamin A deficiency
0.004 0.995 0.000
E60 Dietary zinc deficiency
0.004 0.995 0.000
E59 Dietary selenium deficiency
0.004 0.995 0.000
E52 Niacin deficiency [pellagra]
0.004 0.995 0.000
R73 Elevated blood glucose level
0.005 0.995 0.000
E44.1 Mild protein-energy malnutrition
0.004 0.995 0.000
E44.0 Moderate protein-energy malnutrition
0.004 0.995 0.000
S06.31 Focal brain injury (with open intracranial wound)
0.000 0.995 0.004
E58 Dietary calcium deficiency
0.004 0.995 0.000
E46 Unspecified protein-energy malnutrition
0.004 0.995 0.000
S06.8 Other intracranial injuries
0.000 0.995 0.004
S06.51 Traumatic subdural haemorrhage (with open intracranial wound)
0.000 0.996 0.004
E53 Deficiency of other B group vitamins
0.004 0.996 0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.000 0.996 0.004
E63 Other nutritional deficiencies
0.004 0.996 0.000
N13.5 Kinking and stricture of ureter without hydronephrosis
0.000 0.996 0.004
E16 Other disorders of pancreatic internal secretion
0.004 0.996 0.000
E61 Deficiency of other nutrient elements
0.004 0.996 0.000
M87.9 Osteonecrosis, unspecified
0.004 0.996 0.000
E51 Thiamine deficiency
0.004 0.996 0.000
E54 Ascorbic acid deficiency
0.004 0.996 0.000
S06.9 Intracranial injury, unspecified
0.000 0.996 0.004
C71.2 Temporal lobe
0.004 0.996 0.000
C44.3 Skin of other and unspecified parts of face
0.000 0.996 0.004
C71.6 Cerebellum
0.004 0.996 0.000
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency
0.004 0.996 0.000
C71.8 Overlapping lesion of brain
0.004 0.996 0.000
D51 Vitamin B12 deficiency anaemia
0.004 0.996 0.000
E56.1 Deficiency of vitamin K
0.004 0.996 0.000
E67 Other hyperalimentation
0.004 0.996 0.000
E68 Sequelae of hyperalimentation
0.004 0.996 0.000
S06.10 Traumatic cerebral oedema (without open intracranial wound)
0.000 0.996 0.004
M86.9 Osteomyelitis, unspecified
0.004 0.996 0.000
E53.9 Vitamin B deficiency, unspecified
0.004 0.996 0.000
S06.11 Traumatic cerebral oedema (with open intracranial wound)
0.000 0.996 0.004
C71.0 Cerebrum, except lobes and ventricles
0.004 0.996 0.000
C71.4 Occipital lobe
0.004 0.996 0.000
E61.2 Magnesium deficiency
0.004 0.996 0.000
S06.71 Intracranial injury with prolonged coma (with open intracranial wound)
0.000 0.996 0.004
S06.70 Intracranial injury with prolonged coma (without open intracranial wound)
0.000 0.996 0.004
E56.9 Vitamin deficiency, unspecified
0.004 0.996 0.000
E56.8 Deficiency of other vitamins
0.004 0.996 0.000
E56.0 Deficiency of vitamin E
0.004 0.996 0.000
E21.0 Primary hyperparathyroidism
0.004 0.996 0.000
S06.01 Concussion (with open intracranial wound)
0.000 0.996 0.003
E16.0 Drug-induced hypoglycaemia without coma
0.004 0.996 0.000
M87.98 Osteonecrosis, unspecified (Other)
0.004 0.996 0.000
C71.7 Brain stem
0.004 0.996 0.000
E11.9 Without complications
0.004 0.996 0.000
M86.99 Osteomyelitis, unspecified (Site unspecified)
0.004 0.996 0.000
M86.98 Osteomyelitis, unspecified (Other)
0.004 0.996 0.000
S06.61 Traumatic subarachnoid haemorrhage (with open intracranial wound)
0.000 0.996 0.003
E13.9 Without complications
0.003 0.996 0.000
E50.9 Vitamin A deficiency, unspecified
0.003 0.996 0.000
E50.8 Other manifestations of vitamin A deficiency
0.003 0.996 0.000
E50.7 Other ocular manifestations of vitamin A deficiency
0.003 0.996 0.000
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.003 0.996 0.000
E50.5 Vitamin A deficiency with night blindness
0.003 0.996 0.000
E50.4 Vitamin A deficiency with keratomalacia
0.003 0.996 0.000
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.003 0.996 0.000
E50.2 Vitamin A deficiency with corneal xerosis
0.003 0.996 0.000
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.003 0.996 0.000
E50.0 Vitamin A deficiency with conjunctival xerosis
0.003 0.996 0.000
E64.9 Sequelae of unspecified nutritional deficiency
0.003 0.996 0.000
E64.8 Sequelae of other nutritional deficiencies
0.003 0.996 0.000
E64.3 Sequelae of rickets
0.003 0.996 0.000
E64.2 Sequelae of vitamin C deficiency
0.003 0.996 0.000
E64.1 Sequelae of vitamin A deficiency
0.003 0.996 0.000
E64.0 Sequelae of protein-energy malnutrition
0.003 0.996 0.000
E11.5 With peripheral circulatory complications
0.004 0.996 0.000
S06.00 Concussion (without open intracranial wound)
0.000 0.996 0.003
C71.5 Cerebral ventricle
0.003 0.996 0.000
M86.97 Osteomyelitis, unspecified (Ankle and foot)
0.003 0.996 0.000
Z47.8 Other specified orthopaedic follow-up care
0.004 0.996 0.000
S06.81 Other intracranial injuries (with open intracranial wound)
0.000 0.996 0.003
E53.1 Pyridoxine deficiency
0.003 0.997 0.000
E53.0 Riboflavin deficiency
0.003 0.997 0.000
E63.8 Other specified nutritional deficiencies
0.003 0.997 0.000
E63.1 Imbalance of constituents of food intake
0.003 0.997 0.000
E63.0 Essential fatty acid [EFA] deficiency
0.003 0.997 0.000
D51.8 Other vitamin B12 deficiency anaemias
0.003 0.997 0.000
E16.9 Disorder of pancreatic internal secretion, unspecified
0.003 0.997 0.000
E16.8 Other specified disorders of pancreatic internal secretion
0.003 0.997 0.000
E16.4 Abnormal secretion of gastrin
0.003 0.997 0.000
E16.3 Increased secretion of glucagon
0.003 0.997 0.000
E16.1 Other hypoglycaemia
0.003 0.997 0.000
E61.9 Deficiency of nutrient element, unspecified
0.003 0.997 0.000
E61.8 Deficiency of other specified nutrient elements
0.003 0.997 0.000
E61.7 Deficiency of multiple nutrient elements
0.003 0.997 0.000
E61.6 Vanadium deficiency
0.003 0.997 0.000
E61.5 Molybdenum deficiency
0.003 0.997 0.000
E61.4 Chromium deficiency
0.003 0.997 0.000
E61.3 Manganese deficiency
0.003 0.997 0.000
E61.0 Copper deficiency
0.003 0.997 0.000
M72.27 Plantar fascial fibromatosis-Ankle/Foot
0.000 0.997 0.003
M87.99 Osteonecrosis, unspecified (Site unspecified)
0.003 0.997 0.000
M87.94 Osteonecrosis, unspecified (Hand)
0.003 0.997 0.000
M87.93 Osteonecrosis, unspecified (Forearm)
0.003 0.997 0.000
M87.92 Osteonecrosis, unspecified (Upper arm)
0.003 0.997 0.000
M87.90 Osteonecrosis, unspecified (Multiple sites)
0.003 0.997 0.000
E51.9 Thiamine deficiency, unspecified
0.003 0.997 0.000
E51.8 Other manifestations of thiamine deficiency
0.003 0.997 0.000
E51.1 Beriberi
0.003 0.997 0.000
M86.94 Osteomyelitis, unspecified (Hand)
0.003 0.997 0.000
M87.97 Osteonecrosis, unspecified (Ankle and foot)
0.003 0.997 0.000
S06.60 Traumatic subarachnoid haemorrhage (without open intracranial wound)
0.000 0.997 0.003
S06.91 Intracranial injury, unspecified (with open intracranial wound)
0.000 0.997 0.003
E55 Vitamin D deficiency
0.003 0.997 0.000
E65 Localised adiposity
0.003 0.997 0.000
E63.9 Nutritional deficiency, unspecified
0.003 0.997 0.000
R71 Abnormality of red blood cells
0.003 0.997 0.000
M87.96 Osteonecrosis, unspecified (Lower leg)
0.003 0.997 0.000
M79.69 Pain in limb (Site unspecified)
0.003 0.997 0.000
M86.95 Osteomyelitis, unspecified (Pelvic region and thigh)
0.003 0.997 0.000
D51.3 Other dietary vitamin B12 deficiency anaemia
0.003 0.997 0.000
D51.2 Transcobalamin II deficiency
0.003 0.997 0.000
D51.1 Vitamin B12 deficiency anaemia due to selective vitamin B12 malabsorption with proteinuria
0.003 0.997 0.000
E51.2 Wernicke's encephalopathy
0.003 0.997 0.000
S06.80 Other intracranial injuries (without open intracranial wound)
0.000 0.997 0.003
E67.8 Other specified hyperalimentation
0.003 0.997 0.000
E67.3 Hypervitaminosis D
0.003 0.997 0.000
E67.2 Megavitamin-B6 syndrome
0.003 0.997 0.000
E67.1 Hypercarotenaemia
0.003 0.997 0.000
E67.0 Hypervitaminosis A
0.003 0.997 0.000
K45.8 Other specified abdominal hernia without obstruction or gangrene
0.003 0.997 0.000
M86.93 Osteomyelitis, unspecified (Forearm)
0.003 0.997 0.000
M86.92 Osteomyelitis, unspecified (Upper arm)
0.003 0.997 0.000
M86.91 Osteomyelitis, unspecified (Shoulder region)
0.003 0.997 0.000
M86.90 Osteomyelitis, unspecified (Multiple sites)
0.003 0.997 0.000
M87.91 Osteonecrosis, unspecified (Shoulder region)
0.003 0.997 0.000
L29.0 Pruritus ani
0.000 0.997 0.003
L85.9 Epidermal thickening, unspecified
0.000 0.997 0.003
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.003 0.997 0.000
S02.1 Fracture of base of skull
0.000 0.997 0.003
L82 Seborrhoeic keratosis
0.000 0.997 0.003
O99.8 Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium
0.003 0.997 0.000
M86 Osteomyelitis
0.003 0.997 0.000
R73.0 Abnormal glucose tolerance test
0.003 0.997 0.000
C71.3 Parietal lobe
0.003 0.997 0.000
M43.16 Spondylolisthesis (Lumbar region)
0.003 0.997 0.000
S06.90 Intracranial injury, unspecified (without open intracranial wound)
0.000 0.997 0.002
Z72.0 Tobacco use
0.000 0.997 0.003
M87 Osteonecrosis
0.003 0.997 0.000
R76.0 Raised antibody titer
0.003 0.997 0.000
M86.96 Osteomyelitis, unspecified (Lower leg)
0.003 0.997 0.000
R76 Other abnormal immunological findings in serum
0.003 0.997 0.000
E53.8 Deficiency of other specified B group vitamins
0.003 0.997 0.000
E55.0 Rickets, active
0.002 0.997 0.000
R79.0 Abnormal level of blood mineral
0.003 0.997 0.000
Q28.2 Arteriovenous malformation of cerebral vessels
0.000 0.997 0.003
T83.0 Mechanical complication of urinary (indwelling) catheter
0.000 0.997 0.003
M43.17 Spondylolisthesis (Lumbosacral region)
0.003 0.997 0.000
R72 Abnormality of white blood cells, not elsewhere classified
0.003 0.997 0.000
E61.1 Iron deficiency
0.002 0.997 0.000
M31.6 Other giant cell arteritis
0.003 0.997 0.000
R79 Other abnormal findings of blood chemistry
0.002 0.997 0.000
E04 Other non-toxic goitre
0.002 0.998 0.000
M86.8 Other osteomyelitis
0.002 0.998 0.000
R78 Findings of drugs and other substances, not normally found in blood
0.002 0.998 0.000
R75 Laboratory evidence of human immunodeficiency virus [HIV]
0.002 0.998 0.000
R70 Elevated erythrocyte sedimentation rate and abnormality of plasma viscosity
0.002 0.998 0.000
M86.5 Other chronic haematogenous osteomyelitis
0.002 0.998 0.000
M86.3 Chronic multifocal osteomyelitis
0.002 0.998 0.000
M86.2 Subacute osteomyelitis
0.002 0.998 0.000
M86.0 Acute haematogenous osteomyelitis
0.002 0.998 0.000
M87.1 Osteonecrosis due to drugs
0.002 0.998 0.000
Q21.1 Atrial septal defect
0.000 0.998 0.002
R76.9 Abnormal immunological finding in serum, unspecified
0.002 0.998 0.000
M87.0 Idiopathic aseptic necrosis of bone
0.002 0.998 0.000
H66.3 Other chronic suppurative otitis media
0.002 0.998 0.000
M86.4 Chronic osteomyelitis with draining sinus
0.002 0.998 0.000
M86.1 Other acute osteomyelitis
0.002 0.998 0.000
Z87.3 Personal history of diseases of the musculoskeletal system and connective tissue
0.002 0.998 0.000
M87.3 Other secondary osteonecrosis
0.002 0.998 0.000
M86-M90 Other osteopathies
0.002 0.998 0.000
M86.6 Other chronic osteomyelitis
0.002 0.998 0.000
R76.2 False-positive serological test for syphilis
0.002 0.998 0.000
R76.1 Abnormal reaction to tuberculin test
0.002 0.998 0.000
M87.8 Other osteonecrosis
0.002 0.998 0.000
M88 Paget's disease of bone [osteitis deformans]
0.002 0.998 0.000
M88.99 Paget's disease of bone, unspecified (Site unspecified)
0.002 0.998 0.000
R79.9 Abnormal finding of blood chemistry, unspecified
0.002 0.998 0.000
R77 Other abnormalities of plasma proteins
0.002 0.998 0.000
M86.86 Other osteomyelitis (Lower leg)
0.002 0.998 0.000
M43.1 Spondylolisthesis
0.002 0.998 0.000
S02.11 Fracture of base of skull (open)
0.000 0.998 0.002
R70.0 Elevated erythrocyte sedimentation rate
0.002 0.998 0.000
M88.9 Paget's disease of bone, unspecified
0.002 0.998 0.000
M86.85 Other osteomyelitis (Pelvic region and thigh)
0.002 0.998 0.000
S02.90 Fracture of skull and facial bones, part unspecified (closed)
0.000 0.998 0.002
E04.8 Other specified non-toxic goitre
0.002 0.998 0.000
I86.1 Scrotal varices
0.000 0.998 0.002
Y43.3 Other antineoplastic drugs
0.000 0.998 0.002
M86.89 Other osteomyelitis (Site unspecified)
0.002 0.998 0.000
M86.88 Other osteomyelitis (Other)
0.002 0.998 0.000
M86.84 Other osteomyelitis (Hand)
0.002 0.998 0.000
M86.83 Other osteomyelitis (Forearm)
0.002 0.998 0.000
M86.82 Other osteomyelitis (Upper arm)
0.002 0.998 0.000
M86.81 Other osteomyelitis (Shoulder region)
0.002 0.998 0.000
M86.80 Other osteomyelitis (Multiple sites)
0.002 0.998 0.000
R78.0 Finding of alcohol in blood
0.002 0.998 0.000
M86.47 Chronic osteomyelitis with draining sinus (Ankle and foot)
0.002 0.998 0.000
M86.87 Other osteomyelitis (Ankle and foot)
0.002 0.998 0.000
R78.9 Finding of unspecified substance, not normally found in blood
0.002 0.998 0.000
R78.7 Finding of abnormal level of heavy metals in blood
0.002 0.998 0.000
R78.6 Finding of steroid agent in blood
0.002 0.998 0.000
R78.5 Finding of psychotropic drug in blood
0.002 0.998 0.000
R78.4 Finding of other drugs of addictive potential in blood
0.002 0.998 0.000
R78.3 Finding of hallucinogen in blood
0.002 0.998 0.000
R78.2 Finding of cocaine in blood
0.002 0.998 0.000
R78.1 Finding of opiate drug in blood
0.002 0.998 0.000
M43.10 Spondylolisthesis (Multiple sites in spine)
0.002 0.998 0.000
M87.15 Osteonecrosis due to drugs (Pelvic region and thigh)
0.002 0.998 0.000
Q27.3 Peripheral arteriovenous malformation
0.000 0.998 0.002
M72.2 Plantar fascial fibromatosis
0.000 0.998 0.002
O03.4 Incomplete, without complication
0.002 0.998 0.000
R78.8 Finding of other specified substances, not normally found in blood
0.002 0.998 0.000
Q28 Other congenital malformations of circulatory system
0.000 0.998 0.002
M54.22 Cervicalgia (Cervical region)
0.002 0.998 0.000
M86.09 Acute haematogenous osteomyelitis (Site unspecified)
0.002 0.998 0.000
M86.08 Acute haematogenous osteomyelitis (Other)
0.002 0.998 0.000
M86.07 Acute haematogenous osteomyelitis (Ankle and foot)
0.002 0.998 0.000
M86.06 Acute haematogenous osteomyelitis (Lower leg)
0.002 0.998 0.000
M86.05 Acute haematogenous osteomyelitis (Pelvic region and thigh)
0.002 0.998 0.000
M86.04 Acute haematogenous osteomyelitis (Hand)
0.002 0.998 0.000
M86.03 Acute haematogenous osteomyelitis (Forearm)
0.002 0.998 0.000
M86.02 Acute haematogenous osteomyelitis (Upper arm)
0.002 0.998 0.000
M86.01 Acute haematogenous osteomyelitis (Shoulder region)
0.002 0.998 0.000
M86.00 Acute haematogenous osteomyelitis (Multiple sites)
0.002 0.998 0.000
M86.29 Subacute osteomyelitis (Site unspecified)
0.002 0.998 0.000
M86.28 Subacute osteomyelitis (Other)
0.002 0.998 0.000
M86.27 Subacute osteomyelitis (Ankle and foot)
0.002 0.998 0.000
M86.26 Subacute osteomyelitis (Lower leg)
0.002 0.998 0.000
M86.25 Subacute osteomyelitis (Pelvic region and thigh)
0.002 0.998 0.000
M86.24 Subacute osteomyelitis (Hand)
0.002 0.998 0.000
M86.23 Subacute osteomyelitis (Forearm)
0.002 0.998 0.000
M86.22 Subacute osteomyelitis (Upper arm)
0.002 0.998 0.000
M86.21 Subacute osteomyelitis (Shoulder region)
0.002 0.998 0.000
M86.20 Subacute osteomyelitis (Multiple sites)
0.002 0.998 0.000
M86.39 Chronic multifocal osteomyelitis (Site unspecified)
0.002 0.998 0.000
M86.38 Chronic multifocal osteomyelitis (Other)
0.002 0.998 0.000
M86.37 Chronic multifocal osteomyelitis (Ankle and foot)
0.002 0.998 0.000
M86.36 Chronic multifocal osteomyelitis (Lower leg)
0.002 0.998 0.000
M86.35 Chronic multifocal osteomyelitis (Pelvic region and thigh)
0.002 0.998 0.000
M86.34 Chronic multifocal osteomyelitis (Hand)
0.002 0.998 0.000
M86.33 Chronic multifocal osteomyelitis (Forearm)
0.002 0.998 0.000
M86.32 Chronic multifocal osteomyelitis (Upper arm)
0.002 0.998 0.000
M86.31 Chronic multifocal osteomyelitis (Shoulder region)
0.002 0.998 0.000
M86.30 Chronic multifocal osteomyelitis (Multiple sites)
0.002 0.998 0.000
M86.59 Other chronic haematogenous osteomyelitis (Site unspecified)
0.002 0.998 0.000
M86.58 Other chronic haematogenous osteomyelitis (Other)
0.002 0.998 0.000
M86.57 Other chronic haematogenous osteomyelitis (Ankle and foot)
0.002 0.998 0.000
M86.56 Other chronic haematogenous osteomyelitis (Lower leg)
0.002 0.998 0.000
M86.55 Other chronic haematogenous osteomyelitis (Pelvic region and thigh)
0.002 0.998 0.000
M86.54 Other chronic haematogenous osteomyelitis (Hand)
0.002 0.998 0.000
M86.53 Other chronic haematogenous osteomyelitis (Forearm)
0.002 0.998 0.000
M86.52 Other chronic haematogenous osteomyelitis (Upper arm)
0.002 0.998 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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