TreeWAS – Variant ID: rs4751185

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
K74.6 Other and unspecified cirrhosis of liver	0.000	0.657	0.343
K74 Fibrosis and cirrhosis of liver	0.000	0.657	0.343
K70-K77 Diseases of liver	0.000	0.657	0.343
K70 Alcoholic liver disease	0.000	0.684	0.316
K72 Hepatic failure, not elsewhere classified	0.000	0.688	0.312
K73 Chronic hepatitis, not elsewhere classified	0.000	0.702	0.298
K70.9 Alcoholic liver disease, unspecified	0.000	0.706	0.294
K75 Other inflammatory liver diseases	0.000	0.706	0.294
K72.0 Acute and subacute hepatic failure	0.000	0.722	0.278
K77 Liver disorders in diseases classified elsewhere	0.000	0.723	0.277
K76 Other diseases of liver	0.000	0.727	0.273
K73.9 Chronic hepatitis, unspecified	0.000	0.727	0.273
K74.3 Primary biliary cirrhosis	0.000	0.729	0.271
K70.3 Alcoholic cirrhosis of liver	0.000	0.732	0.268
K71 Toxic liver disease	0.000	0.734	0.266
K72.9 Hepatic failure, unspecified	0.000	0.744	0.256
K74.0 Hepatic fibrosis	0.000	0.745	0.254
K75.8 Other specified inflammatory liver diseases	0.000	0.746	0.254
K74.5 Biliary cirrhosis, unspecified	0.000	0.748	0.251
K76.9 Liver disease, unspecified	0.000	0.751	0.249
K76.6 Portal hypertension	0.000	0.752	0.248
K74.4 Secondary biliary cirrhosis	0.000	0.754	0.246
K74.2 Hepatic fibrosis with hepatic sclerosis	0.000	0.754	0.246
K74.1 Hepatic sclerosis	0.000	0.758	0.241
K70.1 Alcoholic hepatitis	0.000	0.760	0.240
K75.0 Abscess of liver	0.000	0.761	0.239
K72.1 Chronic hepatic failure	0.000	0.775	0.225
K77.0 Liver disorders in infectious and parasitic diseases classified elsewhere	0.000	0.776	0.224
K73.2 Chronic active hepatitis, not elsewhere classified	0.000	0.781	0.219
K73.1 Chronic lobular hepatitis, not elsewhere classified	0.000	0.786	0.214
K73.0 Chronic persistent hepatitis, not elsewhere classified	0.000	0.786	0.214
K70.4 Alcoholic hepatic failure	0.000	0.788	0.212
K75.3 Granulomatous hepatitis, not elsewhere classified	0.000	0.788	0.212
K75.2 Nonspecific reactive hepatitis	0.000	0.789	0.211
K75.1 Phlebitis of portal vein	0.000	0.789	0.211
K75.4 Autoimmune hepatitis	0.000	0.789	0.211
K70.2 Alcoholic fibrosis and sclerosis of liver	0.000	0.791	0.209
K77.8 Liver disorders in other diseases classified elsewhere	0.000	0.793	0.207
K76.3 Infarction of liver	0.000	0.795	0.205
K71.9 Toxic liver disease, unspecified	0.000	0.795	0.205
K70.0 Alcoholic fatty liver	0.000	0.803	0.197
K76.5 Hepatic veno-occlusive disease	0.000	0.804	0.196
K76.4 Peliosis hepatis	0.000	0.804	0.196
K76.2 Central haemorrhagic necrosis of liver	0.000	0.804	0.196
K71.6 Toxic liver disease with hepatitis, not elsewhere classified	0.000	0.805	0.194
K71.0 Toxic liver disease with cholestasis	0.000	0.805	0.194
K76.7 Hepatorenal syndrome	0.000	0.807	0.193
K71.1 Toxic liver disease with hepatic necrosis	0.000	0.808	0.192
K71.8 Toxic liver disease with other disorders of liver	0.000	0.809	0.191
K71.7 Toxic liver disease with fibrosis and cirrhosis of liver	0.000	0.809	0.191
K71.5 Toxic liver disease with chronic active hepatitis	0.000	0.809	0.191
K71.4 Toxic liver disease with chronic lobular hepatitis	0.000	0.809	0.191
K71.3 Toxic liver disease with chronic persistent hepatitis	0.000	0.809	0.191
K71.2 Toxic liver disease with acute hepatitis	0.000	0.809	0.191
K73.8 Other chronic hepatitis, not elsewhere classified	0.000	0.813	0.186
K76.1 Chronic passive congestion of liver	0.000	0.815	0.185
K75.9 Inflammatory liver disease, unspecified	0.000	0.816	0.184
K76.0 Fatty (change of) liver, not elsewhere classified	0.000	0.862	0.138
E04.9 Non-toxic goitre, unspecified	0.028	0.972	0.000
E04 Other non-toxic goitre	0.024	0.976	0.000
E04.1 Non-toxic single thyroid nodule	0.022	0.978	0.000
K76.8 Other specified diseases of liver	0.002	0.978	0.020
E04.2 Non-toxic multinodular goitre	0.020	0.980	0.000
E04.0 Non-toxic diffuse goitre	0.019	0.981	0.000
E04.8 Other specified non-toxic goitre	0.017	0.983	0.000
S82.40 Fracture of fibula alone (closed)	0.000	0.983	0.017
S82.4 Fracture of fibula alone	0.000	0.984	0.016
S82 Fracture of lower leg, including ankle	0.000	0.985	0.015
S82.10 Fracture of upper end of tibia (closed)	0.000	0.985	0.015
S82.1 Fracture of upper end of tibia	0.000	0.985	0.015
S82.3 Fracture of lower end of tibia	0.000	0.986	0.014
S82.6 Fracture of lateral malleolus	0.000	0.987	0.013
S82.31 Fracture of lower end of tibia (open)	0.000	0.988	0.012
S82.8 Fractures of other parts of lower leg	0.000	0.988	0.012
S82.30 Fracture of lower end of tibia (closed)	0.000	0.988	0.012
S82.41 Fracture of fibula alone (open)	0.000	0.988	0.011
Z74.0 Reduced mobility	0.000	0.989	0.011
S82.9 Fracture of lower leg, part unspecified	0.000	0.989	0.011
Z74 Problems related to care-provider dependency	0.000	0.989	0.011
S82.5 Fracture of medial malleolus	0.000	0.989	0.011
S82.60 Fracture of lateral malleolus (closed)	0.000	0.989	0.011
S82.11 Fracture of upper end of tibia (open)	0.000	0.989	0.010
S82.61 Fracture of lateral malleolus (open)	0.000	0.990	0.010
S82.2 Fracture of shaft of tibia	0.000	0.990	0.010
S82.7 Multiple fractures of lower leg	0.000	0.990	0.010
S82.80 Fractures of other parts of lower leg (closed)	0.000	0.990	0.010
Z74.8 Other problems related to care-provider dependency	0.000	0.990	0.009
S82.0 Fracture of patella	0.000	0.991	0.009
D37.4 Colon	0.000	0.991	0.009
Z74.1 Need for assistance with personal care	0.000	0.991	0.009
Z74.9 Problem related to care-provider dependency, unspecified	0.000	0.991	0.009
Z75 Problems related to medical facilities and other health care	0.000	0.991	0.009
S82.90 Fracture of lower leg, part unspecified (closed)	0.000	0.991	0.009
Z74.3 Need for continuous supervision	0.000	0.991	0.009
S82.86 Maisonneuve's fracture	0.000	0.991	0.009
S82.81 Fractures of other parts of lower leg (open)	0.000	0.991	0.009
Z70-Z76 Persons encountering health services in other circumstances	0.000	0.991	0.009
S82.51 Fracture of medial malleolus (open)	0.000	0.992	0.008
S82.21 Fracture of shaft of tibia (open)	0.000	0.992	0.008
Z74.2 Need for assistance at home and no other household member able to render care	0.000	0.992	0.008
Z75.8 Other problems related to medical facilities and other health care	0.000	0.992	0.008
Z71.8 Other specified counselling	0.000	0.992	0.008
Z71 Persons encountering health services for other counselling and medical advice, not elsewhere classified	0.000	0.992	0.008
J33.9 Nasal polyp, unspecified	0.000	0.992	0.008
S82.91 Fracture of lower leg, part unspecified (open)	0.000	0.992	0.007
S82.71 Multiple fractures of lower leg (open)	0.000	0.992	0.007
S82.50 Fracture of medial malleolus (closed)	0.000	0.992	0.007
Z75.3 Unavailability and inaccessibility of health-care facilities	0.000	0.992	0.007
Z75.4 Unavailability and inaccessibility of other helping agencies	0.000	0.993	0.007
Z73 Problems related to life-management difficulty	0.000	0.993	0.007
Z75.1 Person awaiting admission to adequate facility elsewhere	0.000	0.993	0.007
Z75.0 Medical services not available in home	0.000	0.993	0.007
Z73.3 Stress, not elsewhere classified	0.000	0.993	0.007
S82.70 Multiple fractures of lower leg (closed)	0.000	0.993	0.006
Z70 Counselling related to sexual attitude, behaviour and orientation	0.000	0.993	0.007
Z71.6 Tobacco abuse counselling	0.000	0.993	0.007
Z75.9 Unspecified problem related to medical facilities and other health care	0.000	0.993	0.006
S82.01 Fracture of patella (open)	0.000	0.993	0.006
Z73.6 Limitation of activities due to disability	0.000	0.994	0.006
Z75.5 Holiday relief care	0.000	0.994	0.006
Z71.4 Alcohol abuse counselling and surveillance	0.000	0.994	0.006
Z76 Persons encountering health services in other circumstances	0.000	0.994	0.006
Z75.2 Other waiting period for investigation and treatment	0.000	0.994	0.006
S82.20 Fracture of shaft of tibia (closed)	0.000	0.994	0.006
Z71.7 Human immunodeficiency virus [HIV] counselling	0.000	0.994	0.006
Z71.5 Drug abuse counselling and surveillance	0.000	0.994	0.006
Z71.0 Person consulting on behalf of another person	0.000	0.994	0.006
Z71.2 Person consulting for explanation of investigation findings	0.000	0.994	0.006
Z71.1 Person with feared complaint in whom no diagnosis is made	0.000	0.994	0.006
S82.00 Fracture of patella (closed)	0.000	0.994	0.006
Z73.5 Social role conflict, not elsewhere classified	0.000	0.994	0.005
Z73.4 Inadequate social skills, not elsewhere classified	0.000	0.994	0.005
Z73.2 Lack of relaxation and leisure	0.000	0.994	0.005
Z73.1 Accentuation of personality traits	0.000	0.994	0.005
Z73.0 Burn-out	0.000	0.994	0.005
Z70.1 Counselling related to patient's sexual behaviour and orientation	0.000	0.995	0.005
K63.9 Disease of intestine, unspecified	0.000	0.995	0.005
S52.00 Fracture of upper end of ulna (closed)	0.005	0.995	0.000
Z70.9 Sex counselling, unspecified	0.000	0.995	0.005
Z70.8 Other sex counselling	0.000	0.995	0.005
Z70.3 Counselling related to combined concerns regarding sexual attitude, behaviour and orientation	0.000	0.995	0.005
Z70.2 Counselling related to sexual behaviour and orientation of third party	0.000	0.995	0.005
Z70.0 Counselling related to sexual attitude	0.000	0.995	0.005
Z73.8 Other problems related to life-management difficulty	0.000	0.995	0.005
R87.6 Abnormal cytological findings	0.000	0.995	0.005
I71.4 Abdominal aortic aneurysm, without mention of rupture	0.000	0.995	0.005
K29.6 Other gastritis	0.000	0.995	0.005
Z76.8 Persons encountering health services in other specified circumstances	0.000	0.995	0.004
Z76.5 Malingerer [conscious situation]	0.000	0.995	0.004
Z76.4 Other boarder in health-care facility	0.000	0.995	0.004
Z76.2 Health supervision and care of other healthy infant and child	0.000	0.995	0.004
Z76.1 Health supervision and care of foundling	0.000	0.995	0.004
Z76.0 Issue of repeat prescription	0.000	0.995	0.004
N48.6 Balanitis xerotica obliterans	0.005	0.995	0.000
Z71.3 Dietary counselling and surveillance	0.000	0.996	0.004
Z76.9 Persons encountering health services in unspecified circumstances	0.000	0.996	0.004
Z76.3 Healthy person accompanying sick person	0.000	0.996	0.004
Z71.9 Counselling, unspecified	0.000	0.996	0.004
R00.1 Bradycardia, unspecified	0.000	0.996	0.004
Z73.9 Problem related to life-management difficulty, unspecified	0.000	0.997	0.003
S42.20 Fracture of upper end of humerus (closed)	0.000	0.997	0.003
S02.00 Fracture of vault of skull (closed)	0.000	0.997	0.003
S80-S89 Injuries to the knee and lower leg	0.000	0.997	0.003
S52.0 Fracture of upper end of ulna	0.003	0.997	0.000
H83.0 Labyrinthitis	0.000	0.997	0.003
R87 Abnormal findings in specimens from female genital organs	0.000	0.997	0.003
C79.8 Secondary malignant neoplasm of other specified sites	0.003	0.997	0.000
R87.5 Abnormal microbiological findings	0.000	0.997	0.003
J35.8 Other chronic diseases of tonsils and adenoids	0.000	0.997	0.003
E00-E07 Disorders of thyroid gland	0.003	0.997	0.000
Q85.0 Neurofibromatosis (nonmalignant)	0.003	0.997	0.000
S52.01 Fracture of upper end of ulna (open)	0.002	0.997	0.000
S89 Other and unspecified injuries of lower leg	0.000	0.997	0.002
O72.1 Other immediate postpartum haemorrhage	0.002	0.998	0.000
S89.9 Unspecified injury of lower leg	0.000	0.998	0.002
S88 Traumatic amputation of lower leg	0.000	0.998	0.002
S87 Crushing injury of lower leg	0.000	0.998	0.002
Z72 Problems related to lifestyle	0.000	0.998	0.002
S85 Injury of blood vessels at lower leg level	0.000	0.998	0.002
S80 Superficial injury of lower leg	0.000	0.998	0.002
E11.3 With ophthalmic complications	0.000	0.998	0.002
R87.9 Unspecified abnormal finding	0.000	0.998	0.002
R87.0 Abnormal level of enzymes	0.000	0.998	0.002
S84 Injury of nerves at lower leg level	0.000	0.998	0.002
R87.8 Other abnormal findings	0.000	0.998	0.002
R87.4 Abnormal immunological findings	0.000	0.998	0.002
R87.3 Abnormal level of substances chiefly nonmedicinal as to source	0.000	0.998	0.002
R87.2 Abnormal level of other drugs, medicaments and biological substances	0.000	0.998	0.002
R87.1 Abnormal level of hormones	0.000	0.998	0.002
Z83.7 Family history of diseases of the digestive system	0.000	0.998	0.002
Z11.2 Special screening examination for other bacterial diseases	0.000	0.998	0.002
G25.0 Essential tremor	0.000	0.998	0.002
S86 Injury of muscle and tendon at lower leg level	0.000	0.998	0.002
S80.9 Superficial injury of lower leg, unspecified	0.000	0.998	0.002
G31.9 Degenerative disease of nervous system, unspecified	0.000	0.998	0.002
Z72.8 Other problems related to lifestyle	0.000	0.998	0.002
Z72.2 Drug use	0.000	0.998	0.002
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.002	0.998	0.000
E00 Congenital iodine-deficiency syndrome	0.002	0.998	0.000
S89.7 Multiple injuries of lower leg	0.000	0.998	0.002
S89.1 Other specified injuries of lower leg	0.000	0.998	0.002
S89.0 Multiple injuries of lower leg	0.000	0.998	0.002
E06 Thyroiditis	0.002	0.998	0.000
Z72.9 Problem related to lifestyle, unspecified	0.000	0.998	0.002
E11.2 With renal complications	0.000	0.998	0.002
S86.1 Injury of other muscle(s) and tendon(s) of posterior muscle group at lower leg level	0.000	0.998	0.002
G25.8 Other specified extrapyramidal and movement disorders	0.000	0.998	0.002
E02 Subclinical iodine-deficiency hypothyroidism	0.002	0.998	0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee	0.000	0.998	0.002
S88.9 Traumatic amputation of lower leg, level unspecified	0.000	0.998	0.002
S88.1 Traumatic amputation at level between knee and ankle	0.000	0.998	0.002
S88.0 Traumatic amputation at knee level	0.000	0.998	0.002
Z72.6 Gambling and betting	0.000	0.998	0.002
Z72.5 High-risk sexual behaviour	0.000	0.998	0.002
S06.00 Concussion (without open intracranial wound)	0.000	0.998	0.002
E23.0 Hypopituitarism	0.000	0.998	0.002
N80.9 Endometriosis, unspecified	0.000	0.998	0.002
S83.4 Sprain and strain involving (fibular)(tibial) collateral ligamnent of knee	0.000	0.998	0.002
S87.0 Crushing injury of knee	0.000	0.998	0.002
Z72.3 Lack of physical exercise	0.000	0.998	0.002
S85.9 Injury of unspecified blood vessel at lower leg level	0.000	0.998	0.002
S85.8 Injury of other blood vessels at lower leg level	0.000	0.998	0.002
S85.7 Injury of multiple blood vessels at lower leg level	0.000	0.998	0.002
S85.5 Injury of popliteal vein	0.000	0.998	0.002
S85.4 Injury of lesser saphenous vein at lower leg level	0.000	0.998	0.002
S85.3 Injury of greater saphenous vein at lower leg level	0.000	0.998	0.002
S85.2 Injury of peroneal artery	0.000	0.998	0.002
S85.0 Injury of popliteal artery	0.000	0.998	0.002
S87.8 Crushing injury of other and unspecified parts of lower leg	0.000	0.998	0.002
Z11.0 Special screening examination for intestinal infectious diseases	0.000	0.998	0.002
E11.4 With neurological complications	0.000	0.998	0.002
S84.9 Injury of unspecified nerve at lower leg level	0.000	0.998	0.002
S84.8 Injury of other nerves at lower leg level	0.000	0.998	0.002
S84.7 Injury of multiple nerves at lower leg level	0.000	0.998	0.002
S84.2 Injury of cutaneous sensory nerve at lower leg level	0.000	0.998	0.002
S84.0 Injury of tibial nerve at lower leg level	0.000	0.998	0.002
M65.91 Synovitis and tenosynovitis, unspecified (Shoulder region)	0.002	0.998	0.000
H54.7 Unspecified visual loss	0.000	0.998	0.002
S85.1 Injury of (anterior)(posterior) tibial artery	0.000	0.998	0.002
S86.9 Injury of unspecified muscle and tendon at lower leg level	0.000	0.998	0.002
S80.1 Contusion of other and unspecified parts of lower leg	0.000	0.998	0.002
J33 Nasal polyp	0.000	0.998	0.002
S80.8 Other superficial injuries of lower leg	0.000	0.998	0.002
S86.0 Injury of Achilles tendon	0.000	0.998	0.002
S86.7 Injury of multiple muscles and tendons at lower leg level	0.000	0.998	0.002
S86.3 Injury of muscle(s) and tendon(s) of peroneal muscle group at lower leg level	0.000	0.998	0.002
S02.0 Fracture of vault of skull	0.000	0.998	0.002
S84.1 Injury of peroneal nerve at lower leg level	0.000	0.998	0.002
S89.8 Other specified injuries of lower leg	0.000	0.998	0.002
E11.6 With other specified complications	0.000	0.998	0.002
S83.1 Dislocation of knee	0.000	0.998	0.002
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.002	0.998	0.000
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.002	0.998	0.000
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.002	0.998	0.000
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.002	0.998	0.000
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.002	0.998	0.000
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.002	0.998	0.000
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.002	0.998	0.000
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.002	0.998	0.000
E06.1 Subacute thyroiditis	0.002	0.998	0.000
R47.8 Other and unspecified speech disturbances	0.000	0.998	0.002
E06.9 Thyroiditis, unspecified	0.002	0.998	0.000
E06.4 Drug-induced thyroiditis	0.002	0.998	0.000
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.002	0.998	0.000
E06.0 Acute thyroiditis	0.002	0.998	0.000
S80.0 Contusion of knee	0.000	0.998	0.002
K29.0 Acute haemorrhagic gastritis	0.000	0.998	0.002
S86.2 Injury of muscle(s) and tendon(s) of anterior muscle group at lower leg level	0.000	0.998	0.002
Z72.4 Inappropriate diet and eating habits	0.000	0.998	0.002
E06.5 Other chronic thyroiditis	0.002	0.998	0.000
R87.7 Abnormal histological findings	0.000	0.998	0.001
S80.7 Multiple superficial injuries of lower leg	0.000	0.998	0.002
E11 Non-insulin-dependent diabetes mellitus	0.000	0.998	0.002
S02.60 Fracture of mandible (closed)	0.000	0.998	0.002
M54.46 Lumbago with sciatica (Lumbar region)	0.000	0.998	0.002
I85.9 Oesophageal varices without bleeding	0.000	0.998	0.002
S83.0 Dislocation of patella	0.000	0.998	0.002
E07 Other disorders of thyroid	0.002	0.998	0.000
E06.3 Autoimmune thyroiditis	0.002	0.998	0.000
S51.0 Open wound of elbow	0.000	0.998	0.002
Z11 Special screening examination for infectious and parasitic diseases	0.000	0.998	0.002
H83.8 Other specified diseases of inner ear	0.000	0.998	0.002
G25 Other extrapyramidal and movement disorders	0.000	0.998	0.002
H83 Other diseases of inner ear	0.000	0.998	0.002
Q85 Phakomatoses, not elsewhere classified	0.002	0.998	0.000
G61.0 Guillain-Barre syndrome	0.002	0.998	0.000
I87.2 Venous insufficiency (chronic) (peripheral)	0.002	0.998	0.000
S02.01 Fracture of vault of skull (open)	0.000	0.998	0.001
S86.00 Unspecified injury of Achilles tendon	0.000	0.998	0.001
S83.5 Sprain and strain involving (anterior)(posterior) cruciate ligament of knee	0.000	0.998	0.002
S83.3 Tear of articular cartilage of knee, current	0.000	0.998	0.001
S83.7 Injury to multiple structures of knee	0.000	0.998	0.001
S83.2 Tear of meniscus, current	0.000	0.998	0.002
E11.8 With unspecified complications	0.000	0.998	0.002
G25.1 Drug-induced tremor	0.000	0.998	0.002
R26.2 Difficulty in walking, not elsewhere classified	0.000	0.998	0.002
Z11.4 Special screening examination for human immunodeficiency virus [HIV]	0.000	0.998	0.002
G37.9 Demyelinating disease of central nervous system, unspecified	0.002	0.998	0.000
Q85.8 Other phakomatoses, not elsewhere classified	0.001	0.998	0.000
D23.7 Skin of lower limb, including hip	0.002	0.998	0.000
H43.3 Other vitreous opacities	0.000	0.998	0.002
Z11.6 Special screening examination for other protozoal diseases and helminthiases	0.000	0.998	0.001
E11.0 With coma	0.000	0.998	0.001
R44.3 Hallucinations, unspecified	0.002	0.998	0.000
Z83.5 Family history of eye and ear disorders	0.000	0.998	0.002
E05 Thyrotoxicosis [hyperthyroidism]	0.002	0.998	0.000
S06.60 Traumatic subarachnoid haemorrhage (without open intracranial wound)	0.000	0.998	0.001
J33.0 Polyp of nasal cavity	0.000	0.998	0.002
S42.2 Fracture of upper end of humerus	0.000	0.998	0.001
D13.2 Duodenum	0.000	0.998	0.002
E07.1 Dyshormogenetic goitre	0.001	0.998	0.000
E07.0 Hypersecretion of calcitonin	0.001	0.998	0.000
E11.1 With ketoacidosis	0.000	0.998	0.001
H50.1 Divergent concomitant strabismus	0.000	0.998	0.002
M19.96 Arthrosis, unspecified-Lower leg	0.000	0.998	0.001
S86.8 Injury of other muscles and tendons at lower leg level	0.000	0.998	0.001
S91.1 Open wound of toe(s) without damage to nail	0.001	0.998	0.000
Z11.3 Special screening examination for infections with a predominantly sexual mode of transmission	0.000	0.998	0.001
D03.7 Melanoma in situ of lower limb, including hip	0.001	0.999	0.000
G25.6 Drug-induced tics and other tics of organic origin	0.000	0.999	0.001
G25.4 Drug-induced chorea	0.000	0.999	0.001
G90.2 Horner's syndrome	0.000	0.999	0.001
H83.1 Labyrinthine fistula	0.000	0.999	0.001
J33.1 Polypoid sinus degeneration	0.000	0.999	0.001
R84.5 Abnormal microbiological findings	0.000	0.999	0.001
H83.2 Labyrinthine dysfunction	0.000	0.999	0.001
Z11.9 Special screening examination for infectious and parasitic diseases, unspecified	0.000	0.999	0.001
Z11.5 Special screening examination for other viral diseases	0.000	0.999	0.001
Z11.1 Special screening examination for respiratory tuberculosis	0.000	0.999	0.001
D37.2 Small intestine	0.000	0.999	0.001
G25.5 Other chorea	0.000	0.999	0.001
G99.2 Myelopathy in diseases classified elsewhere	0.001	0.999	0.000
R84 Abnormal findings in specimens from respiratory organs and thorax	0.000	0.999	0.001
E11.7 With multiple complications	0.000	0.999	0.001
H83.9 Disease of inner ear, unspecified	0.000	0.999	0.001
O46.9 Antepartum haemorrhage, unspecified	0.001	0.999	0.000
Q85.9 Phakomatosis, unspecified	0.001	0.999	0.000
R47.1 Dysarthria and anarthria	0.000	0.999	0.001
M54.22 Cervicalgia (Cervical region)	0.000	0.999	0.001
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.001	0.999	0.000
G25.9 Extrapyramidal and movement disorder, unspecified	0.000	0.999	0.001
Q85.1 Tuberous sclerosis	0.001	0.999	0.000
T14.0 Superficial injury of unspecified body region	0.000	0.999	0.001
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis	0.000	0.999	0.001
G25.2 Other specified forms of tremor	0.000	0.999	0.001
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs	0.000	0.999	0.001
H18.4 Corneal degeneration	0.000	0.999	0.001
R84.6 Abnormal cytological findings	0.000	0.999	0.001
E05.5 Thyroid crisis or storm	0.001	0.999	0.000
E05.4 Thyrotoxicosis factitia	0.001	0.999	0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.001	0.999	0.000
E78.2 Mixed hyperlipidaemia	0.001	0.999	0.000
H83.3 Noise effects on inner ear	0.000	0.999	0.001
N48.4 Impotence of organic origin	0.001	0.999	0.000
Z11.8 Special screening examination for other infectious and parasitic diseases	0.000	0.999	0.001
S92.00 Fracture of calcaneus (closed)	0.001	0.999	0.000
C15.9 Oesophagus, unspecified	0.001	0.999	0.000
E05.8 Other thyrotoxicosis	0.001	0.999	0.000
H69.9 Eustachian tube disorder, unspecified	0.001	0.999	0.000
J32.0 Chronic maxillary sinusitis	0.000	0.999	0.001
O47.0 False labour before 37 completed weeks of gestation	0.001	0.999	0.000
R27.0 Ataxia, unspecified	0.001	0.999	0.000
R83 Abnormal findings in cerebrospinal fluid	0.000	0.999	0.001
S42.21 Fracture of upper end of humerus (open)	0.000	0.999	0.001
K57.1 Diverticular disease of small intestine without perforation or abscess	0.001	0.999	0.000
S02.6 Fracture of mandible	0.000	0.999	0.001
E07.8 Other specified disorders of thyroid	0.001	0.999	0.000
R83.5 Abnormal microbiological findings	0.000	0.999	0.001
R84.8 Other abnormal findings	0.000	0.999	0.001
R84.7 Abnormal histological findings	0.000	0.999	0.001
R84.4 Abnormal immunological findings	0.000	0.999	0.001
R84.3 Abnormal level of substances chiefly nonmedicinal as to source	0.000	0.999	0.001
R84.2 Abnormal level of other drugs, medicaments and biological substances	0.000	0.999	0.001
R84.1 Abnormal level of hormones	0.000	0.999	0.001
R84.0 Abnormal level of enzymes	0.000	0.999	0.001
S83.6 Sprain and strain of other and unspecified parts of knee	0.000	0.999	0.001
Q82.8 Other specified congenital malformations of skin	0.000	0.999	0.001
R89.7 Abnormal histological findings	0.000	0.999	0.001
R89 Abnormal findings in specimens from other organs, systems and tissues	0.000	0.999	0.001
M54.28 Cervicalgia-Sacral/sacrococ	0.000	0.999	0.001
N13.2 Hydronephrosis with renal and ureteral calculous obstruction	0.000	0.999	0.001
N48.9 Disorder of penis, unspecified	0.001	0.999	0.000
S06.0 Concussion	0.000	0.999	0.001
S81 Open wound of lower leg	0.000	0.999	0.001
M71.26 Synovial cyst of popliteal space [Baker]-Lower Leg	0.000	0.999	0.001
D03.5 Melanoma in situ of trunk	0.001	0.999	0.000
D37.6 Liver, gallbladder and bile ducts	0.000	0.999	0.001
I80.8 Phlebitis and thrombophlebitis of other sites	0.000	0.999	0.001
N48 Other disorders of penis	0.001	0.999	0.000
S92.51 Fracture of other toe (open)	0.001	0.999	0.000
J35.2 Hypertrophy of adenoids	0.000	0.999	0.001
O10.0 Pre-existing essential hypertension complicating pregnancy, childbirth and the puerperium	0.000	0.999	0.001
R84.9 Unspecified abnormal finding	0.000	0.999	0.001
R89.8 Other abnormal findings	0.000	0.999	0.001
S91 Open wound of ankle and foot	0.001	0.999	0.000
M88.90 Paget's disease of bone, unspecified (Multiple sites)	0.000	0.999	0.001
D37.3 Appendix	0.000	0.999	0.001
E07.9 Disorder of thyroid, unspecified	0.001	0.999	0.000
I85.0 Oesophageal varices with bleeding	0.000	0.999	0.001
I98.2 Oesophageal varices in diseases classified elsewhere	0.000	0.999	0.001
J35.9 Chronic disease of tonsils and adenoids, unspecified	0.000	0.999	0.001
Q67.5 Congenital deformity of spine	0.000	0.999	0.001
R83.9 Unspecified abnormal finding	0.000	0.999	0.001
R83.7 Abnormal histological findings	0.000	0.999	0.001
R83.6 Abnormal cytological findings	0.000	0.999	0.001
R83.4 Abnormal immunological findings	0.000	0.999	0.001
R83.3 Abnormal level of substances chiefly nonmedicinal as to source	0.000	0.999	0.001
R83.2 Abnormal level of other drugs, medicaments and biological substances	0.000	0.999	0.001
R83.1 Abnormal level of hormones	0.000	0.999	0.001
R83.0 Abnormal level of enzymes	0.000	0.999	0.001
R86.5 Abnormal microbiological findings	0.000	0.999	0.001
S91.3 Open wound of other parts of foot	0.001	0.999	0.000
J35 Chronic diseases of tonsils and adenoids	0.000	0.999	0.001
R47 Speech disturbances, not elsewhere classified	0.000	0.999	0.001
S02.61 Fracture of mandible (open)	0.000	0.999	0.001
E11.5 With peripheral circulatory complications	0.000	0.999	0.001
S06.01 Concussion (with open intracranial wound)	0.000	0.999	0.001
S92.30 Fracture of metatarsal bone (closed)	0.000	0.999	0.001
H47.3 Other disorders of optic disk	0.001	0.999	0.000
J35.1 Hypertrophy of tonsils	0.000	0.999	0.001
Q66.7 Pes cavus	0.001	0.999	0.000
R50.9 Fever, unspecified	0.000	0.999	0.001
R83.8 Other abnormal findings	0.000	0.999	0.001
R89.5 Abnormal microbiological findings	0.000	0.999	0.001
R89.4 Abnormal immunological findings	0.000	0.999	0.001
R89.3 Abnormal level of substances chiefly nonmedicinal as to source	0.000	0.999	0.001
R89.2 Abnormal level of other drugs, medicaments and biological substances	0.000	0.999	0.001
R89.1 Abnormal level of hormones	0.000	0.999	0.001
R89.0 Abnormal level of enzymes	0.000	0.999	0.001
S92.0 Fracture of calcaneus	0.001	0.999	0.000
T14.6 Injury of tendons and muscles of unspecified body region	0.000	0.999	0.001
R86 Abnormal findings in specimens from male genital organs	0.000	0.999	0.001
S92.50 Fracture of other toe (closed)	0.001	0.999	0.000
D17.6 Benign lipomatous neoplasm of spermatic cord	0.000	0.999	0.001
N48.0 Leukoplakia of penis	0.001	0.999	0.000
S92.5 Fracture of other toe	0.001	0.999	0.000
D13.1 Stomach	0.000	0.999	0.001
G24.9 Dystonia, unspecified	0.000	0.999	0.001
H25.1 Senile nuclear cataract	0.000	0.999	0.001
H66.9 Otitis media, unspecified	0.000	0.999	0.001
N41.1 Chronic prostatitis	0.000	0.999	0.001
N48.1 Balanoposthitis	0.001	0.999	0.000
Q65.8 Other congenital deformities of hip	0.001	0.999	0.000
R86.7 Abnormal histological findings	0.000	0.999	0.001
S91.7 Multiple open wounds of ankle and foot	0.001	0.999	0.000
S91.0 Open wound of ankle	0.001	0.999	0.000
T43.3 Phenothiazine antipsychotics and neuroleptics	0.000	0.999	0.001
G25.3 Myoclonus	0.000	0.999	0.001
H49.2 Sixth [abducent] nerve palsy	0.001	0.999	0.000
J35.3 Hypertrophy of tonsils with hypertrophy of adenoids	0.000	0.999	0.001
R22.2 Localised swelling, mass and lump, trunk	0.000	0.999	0.001
R86.0 Abnormal level of enzymes	0.000	0.999	0.001
R89.9 Unspecified abnormal finding	0.000	0.999	0.001
R89.6 Abnormal cytological findings	0.000	0.999	0.001
S81.7 Multiple open wounds of lower leg	0.000	0.999	0.001
V04.1 Traffic accident	0.000	0.999	0.001
Z83.2 Family history of diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.000	0.999	0.001
M65.43 Radial styloid tenosynovitis [de Quervain] (Forearm)	0.001	0.999	0.000
M81.98 Osteoporosis, unspecified (Other)	0.001	0.999	0.000
E05.0 Thyrotoxicosis with diffuse goitre	0.001	0.999	0.000
Q18.0 Sinus, fistula and cyst of branchial cleft	0.001	0.999	0.000
R86.9 Unspecified abnormal finding	0.000	0.999	0.001
R86.4 Abnormal immunological findings	0.000	0.999	0.001
R86.3 Abnormal level of substances chiefly nonmedicinal as to source	0.000	0.999	0.001
R86.2 Abnormal level of other drugs, medicaments and biological substances	0.000	0.999	0.001
S93.1 Dislocation of toe(s)	0.001	0.999	0.000
Z80.9 Family history of malignant neoplasm, unspecified	0.000	0.999	0.001
M54.29 Cervicalgia-Site unspe	0.000	0.999	0.001
S92.01 Fracture of calcaneus (open)	0.001	0.999	0.000
S92.41 Fracture of great toe (open)	0.001	0.999	0.000
D13.3 Other and unspecified parts of small intestine	0.000	0.999	0.001
D37.9 Digestive organ, unspecified	0.000	0.999	0.001
D37.0 Lip, oral cavity and pharynx	0.000	0.999	0.001
E05.9 Thyrotoxicosis, unspecified	0.001	0.999	0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.001	0.999	0.000
L50.0 Allergic urticaria	0.001	0.999	0.000
R86.1 Abnormal level of hormones	0.000	0.999	0.001
S91.2 Open wound of toe(s) with damage to nail	0.001	0.999	0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified	0.000	0.999	0.001
D37.1 Stomach	0.000	0.999	0.001
R85 Abnormal findings in specimens from digestive organs and abdominal cavity	0.000	0.999	0.001
M81.95 Osteoporosis, unspecified (Pelvic region and thigh)	0.001	0.999	0.000
S42.10 Fracture of scapula (closed)	0.001	0.999	0.000
S92.70 Multiple fractures of foot (closed)	0.001	0.999	0.000
G31.0 Circumscribed brain atrophy	0.000	0.999	0.001
H18.8 Other specified disorders of cornea	0.000	0.999	0.001
H47.2 Optic atrophy	0.001	0.999	0.000
R85.6 Abnormal cytological findings	0.000	0.999	0.001
R86.6 Abnormal cytological findings	0.000	0.999	0.001
U80.0 Penicillin resistant agent	0.000	0.999	0.001
I70.20 Atherosclerosis of arteries of extremities (without gangrene)	0.001	0.999	0.000
M54.49 Lumbago with sciatica (Site unspecified)	0.000	0.999	0.001
D73.0 Hyposplenism	0.001	0.999	0.000
E23.6 Other disorders of pituitary gland	0.000	0.999	0.001
F80.1 Expressive language disorder	0.001	0.999	0.000
G31.1 Senile degeneration of brain, not elsewhere classified	0.000	0.999	0.001
K05.6 Periodontal disease, unspecified	0.001	0.999	0.000
M54.2 Cervicalgia	0.000	0.999	0.001
N48.5 Ulcer of penis	0.001	0.999	0.000
N95.8 Other specified menopausal and perimenopausal disorders	0.000	0.999	0.001

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations