TreeWAS – Variant ID: rs4756846

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
H65-H75 Diseases of middle ear and mastoid	0.030	0.970	0.000
H72 Perforation of tympanic membrane	0.029	0.971	0.000
H71 Cholesteatoma of middle ear	0.028	0.972	0.000
H66 Suppurative and unspecified otitis media	0.028	0.972	0.000
H72.9 Perforation of tympanic membrane, unspecified	0.027	0.973	0.000
H73 Other disorders of tympanic membrane	0.027	0.973	0.000
H66.3 Other chronic suppurative otitis media	0.026	0.974	0.000
H72.0 Central perforation of tympanic membrane	0.026	0.974	0.000
H73.8 Other specified disorders of tympanic membrane	0.025	0.975	0.000
H70 Mastoiditis and related conditions	0.023	0.977	0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere	0.022	0.978	0.000
H68 Eustachian salpingitis and obstruction	0.022	0.978	0.000
H67 Otitis media in diseases classified elsewhere	0.022	0.978	0.000
H72.8 Other perforations of tympanic membrane	0.022	0.978	0.000
H72.1 Attic perforation of tympanic membrane	0.022	0.978	0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma	0.021	0.979	0.000
C85.7 Other specified types of non-Hodgkin's lymphoma	0.021	0.979	0.000
H74 Other disorders of middle ear and mastoid	0.020	0.979	0.000
Chapter VIII Diseases of the ear and mastoid process	0.020	0.980	0.000
C85.1 B-cell lymphoma, unspecified	0.020	0.980	0.000
H66.4 Suppurative otitis media, unspecified	0.020	0.980	0.000
H66.2 Chronic atticoantral suppurative otitis media	0.020	0.980	0.000
H66.1 Chronic tubotympanic suppurative otitis media	0.020	0.980	0.000
H66.0 Acute suppurative otitis media	0.020	0.980	0.000
H69 Other disorders of Eustachian tube	0.020	0.980	0.000
H73.9 Disorder of tympanic membrane, unspecified	0.020	0.980	0.000
H73.1 Chronic myringitis	0.020	0.980	0.000
H73.0 Acute myringitis	0.020	0.980	0.000
H74.0 Tympanosclerosis	0.020	0.980	0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.020	0.980	0.000
H72.2 Other marginal perforations of tympanic membrane	0.019	0.980	0.000
H60-H62 Diseases of external ear	0.019	0.981	0.000
H65 Nonsuppurative otitis media	0.019	0.981	0.000
C91 Lymphoid leukaemia	0.019	0.981	0.000
H66.9 Otitis media, unspecified	0.019	0.981	0.000
C91.1 Chronic lymphocytic leukaemia	0.018	0.982	0.000
H70.8 Other mastoiditis and related conditions	0.018	0.982	0.000
H61 Other disorders of external ear	0.018	0.982	0.000
H60 Otitis externa	0.017	0.983	0.000
C92 Myeloid leukaemia	0.017	0.983	0.000
H69.8 Other specified disorders of Eustachian tube	0.016	0.983	0.000
H70.2 Petrositis	0.016	0.983	0.000
H70.1 Chronic mastoiditis	0.016	0.983	0.000
H70.0 Acute mastoiditis	0.016	0.983	0.000
C93 Monocytic leukaemia	0.016	0.984	0.000
C88 Malignant immunoproliferative diseases	0.016	0.984	0.000
H67.8 Otitis media in other diseases classified elsewhere	0.016	0.984	0.000
H67.1 Otitis media in viral diseases classified elsewhere	0.016	0.984	0.000
H67.0 Otitis media in bacterial diseases classified elsewhere	0.016	0.984	0.000
H68.1 Obstruction of Eustachian tube	0.016	0.984	0.000
H68.0 Eustachian salpingitis	0.016	0.984	0.000
H75.8 Other specified disorders of middle ear and mastoid in diseases classified elsewhere	0.016	0.984	0.000
H75.0 Mastoiditis in infectious and parasitic diseases classified elsewhere	0.016	0.984	0.000
H65.4 Other chronic nonsuppurative otitis media	0.016	0.984	0.000
C91.4 Hairy-cell leukaemia	0.016	0.984	0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma	0.016	0.984	0.000
C83 Diffuse non-Hodgkin's lymphoma	0.016	0.984	0.000
H70.9 Mastoiditis, unspecified	0.015	0.984	0.000
C81 Hodgkin's disease	0.015	0.985	0.000
C85.2 Mediastinal (thymic) large B-cell lymphoma	0.015	0.985	0.000
C85.0 Lymphosarcoma	0.015	0.985	0.000
H74.2 Discontinuity and dislocation of ear ossicles	0.015	0.985	0.000
H74.1 Adhesive middle ear disease	0.015	0.985	0.000
H80-H83 Diseases of inner ear	0.015	0.985	0.000
H61.9 Disorder of external ear, unspecified	0.015	0.985	0.000
H61.1 Non-infective disorders of pinna	0.015	0.985	0.000
H69.0 Patulous Eustachian tube	0.014	0.985	0.000
H60.9 Otitis externa, unspecified	0.014	0.986	0.000
H61.3 Acquired stenosis of external ear canal	0.014	0.986	0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue	0.014	0.986	0.000
C95 Leukaemia of unspecified cell type	0.014	0.986	0.000
C94 Other leukaemias of specified cell type	0.014	0.986	0.000
C86 Other specified types of T/NK-cell lymphoma	0.014	0.986	0.000
C82.9 Follicular non-Hodgkin's lymphoma, unspecified	0.014	0.986	0.000
C93.1 Chronic monocytic leukaemia	0.014	0.986	0.000
H62 Disorders of external ear in diseases classified elsewhere	0.014	0.986	0.000
C92.4 Acute promyelocytic leukaemia	0.014	0.986	0.000
H65.9 Nonsuppurative otitis media, unspecified	0.014	0.986	0.000
H65.1 Other acute nonsuppurative otitis media	0.014	0.986	0.000
H65.0 Acute serous otitis media	0.014	0.986	0.000
C91.9 Lymphoid leukaemia, unspecified	0.014	0.986	0.000
C91.8 Mature B-cell leukaemia Burkitt-type	0.014	0.986	0.000
C91.7 Other lymphoid leukaemia	0.014	0.986	0.000
C91.6 Prolymphocytic leukaemia of T-cell type	0.014	0.986	0.000
C91.5 Adult T-cell leukaemia	0.014	0.986	0.000
C91.3 Prolymphocytic leukaemia	0.014	0.986	0.000
C91.2 Subacute lymphocytic leukaemia	0.014	0.986	0.000
H61.8 Other specified disorders of external ear	0.014	0.986	0.000
H60.1 Cellulitis of external ear	0.013	0.986	0.000
C92.0 Acute myeloid leukaemia	0.013	0.987	0.000
H74.4 Polyp of middle ear	0.013	0.987	0.000
H60.3 Other infective otitis externa	0.013	0.987	0.000
C88.4 Extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue [MALT-lymphoma]	0.013	0.987	0.000
H60.8 Other otitis externa	0.013	0.987	0.000
C83.0 Small cell (diffuse)	0.013	0.987	0.000
H61.2 Impacted cerumen	0.013	0.987	0.000
H65.2 Chronic serous otitis media	0.013	0.987	0.000
H81 Disorders of vestibular function	0.013	0.987	0.000
C91.0 Acute lymphoblastic leukaemia	0.013	0.987	0.000
C84 Peripheral and cutaneous T-cell lymphomas	0.013	0.987	0.000
C81.9 Hodgkin's disease, unspecified	0.013	0.987	0.000
C88.0 Waldenstrom's macroglobulinaemia	0.012	0.987	0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type	0.013	0.987	0.000
H60.5 Acute otitis externa, non-infective	0.012	0.987	0.000
H60.4 Cholesteatoma of external ear	0.012	0.987	0.000
H60.2 Malignant otitis externa	0.012	0.987	0.000
H60.0 Abscess of external ear	0.012	0.987	0.000
H74.9 Disorder of middle ear and mastoid, unspecified	0.012	0.987	0.000
C92.9 Myeloid leukaemia, unspecified	0.012	0.988	0.000
C92.8 Acute myeloid leukaemia with multilineage dysplasia	0.012	0.988	0.000
C92.7 Other myeloid leukaemia	0.012	0.988	0.000
C92.6 Acute myeloid leukaemia with 11q23-abnormality	0.012	0.988	0.000
C92.5 Acute myelomonocytic leukaemia	0.012	0.988	0.000
C92.3 Myeloid sarcoma	0.012	0.988	0.000
C92.2 Subacute myeloid leukaemia	0.012	0.988	0.000
C83.1 Small cleaved cell (diffuse)	0.012	0.988	0.000
C93.9 Monocytic leukaemia, unspecified	0.012	0.988	0.000
C93.7 Other monocytic leukaemia	0.012	0.988	0.000
C93.3 Juvenile myelomonocytic leukaemia	0.012	0.988	0.000
C93.2 Subacute monocytic leukaemia	0.012	0.988	0.000
C93.0 Acute monocytic leukaemia	0.012	0.988	0.000
C81.0 Lymphocytic predominance	0.012	0.988	0.000
H74.8 Other specified disorders of middle ear and mastoid	0.012	0.988	0.000
C88.9 Malignant immunoproliferative disease, unspecified	0.012	0.988	0.000
C88.7 Other malignant immunoproliferative diseases	0.012	0.988	0.000
C88.3 Immunoproliferative small intestinal disease	0.012	0.988	0.000
C88.2 Gamma heavy chain disease	0.012	0.988	0.000
C88.1 Alpha heavy chain disease	0.012	0.988	0.000
H90-H95 Other disorders of ear	0.012	0.988	0.000
C83.7 Burkitt's tumour	0.012	0.988	0.000
C83.9 Diffuse non-Hodgkin's lymphoma, unspecified	0.012	0.988	0.000
C92.1 Chronic myeloid leukaemia	0.011	0.988	0.000
C82.6 Cutaneous follicle centre lymphoma	0.011	0.988	0.000
C82.5 Diffuse follicle centre lymphoma	0.011	0.988	0.000
C82.4 Follicular lymphoma grade IIIb	0.011	0.988	0.000
C82.3 Follicular lymphoma grade IIIa	0.011	0.988	0.000
C82.2 Large cell, follicular	0.011	0.988	0.000
C83.6 Undifferentiated (diffuse)	0.011	0.988	0.000
C83.5 Lymphoblastic (diffuse)	0.011	0.988	0.000
C83.4 Immunoblastic (diffuse)	0.011	0.988	0.000
C83.2 Mixed small and large cell (diffuse)	0.011	0.988	0.000
C81.7 Other Hodgkin's disease	0.011	0.989	0.000
C81.4 Lymphocyte-rich classical Hodgkin lymphoma	0.011	0.989	0.000
C81.3 Lymphocytic depletion	0.011	0.989	0.000
C81.2 Mixed cellularity	0.011	0.989	0.000
H81.2 Vestibular neuronitis	0.011	0.989	0.000
C83.3 Large cell (diffuse)	0.011	0.989	0.000
H82 Vertiginous syndromes in diseases classified elsewhere	0.011	0.989	0.000
C82.0 Small cleaved cell, follicular	0.011	0.989	0.000
H74.3 Other acquired abnormalities of ear ossicles	0.011	0.989	0.000
C83.8 Other types of diffuse non-Hodgkin's lymphoma	0.011	0.989	0.000
C82.7 Other types of follicular non-Hodgkin's lymphoma	0.010	0.989	0.000
H80 Otosclerosis	0.011	0.989	0.000
C86.6 Primary cutaneous CD30-positive T-cell proliferations	0.010	0.989	0.000
C86.5 Angioimmunoblastic T-cell lymphoma	0.010	0.989	0.000
C86.4 Blastic NK-cell lymphoma	0.010	0.989	0.000
C86.3 Subcutaneous panniculitis-like T-cell lymphoma	0.010	0.989	0.000
C86.2 Enteropathy-type (intestinal) T-cell lymphoma	0.010	0.989	0.000
C86.1 Hepatosplenic T-cell lymphoma	0.010	0.989	0.000
C86.0 Extranodal NK/T-cell lymphoma, nasal type	0.010	0.989	0.000
C94.7 Other specified leukaemias	0.010	0.989	0.000
C94.6 Myelodysplastic and myeloproliferative disease, not elsewhere classified	0.010	0.989	0.000
C94.5 Acute myelofibrosis	0.010	0.989	0.000
C94.4 Acute panmyelosis	0.010	0.989	0.000
C94.3 Mast cell leukaemia	0.010	0.989	0.000
C94.2 Acute megakaryoblastic leukaemia	0.010	0.989	0.000
C94.1 Chronic erythraemia	0.010	0.989	0.000
C94.0 Acute erythraemia and erythroleukaemia	0.010	0.989	0.000
C95.9 Leukaemia, unspecified	0.010	0.989	0.000
C95.7 Other leukaemia of unspecified cell type	0.010	0.989	0.000
C95.2 Subacute leukaemia of unspecified cell type	0.010	0.989	0.000
C95.1 Chronic leukaemia of unspecified cell type	0.010	0.989	0.000
C95.0 Acute leukaemia of unspecified cell type	0.010	0.989	0.000
C96.9 Malignant neoplasms of lymphoid, haematopoietic and related tissue, unspecified	0.010	0.989	0.000
C96.8 Histiocytic sarcoma	0.010	0.989	0.000
C96.7 Other specified malignant neoplasms of lymphoid, haematopoietic and related tissue	0.010	0.989	0.000
C96.6 Unifocal Langerhans-cell histiocytosis	0.010	0.989	0.000
C96.5 Multifocal and unisystemic Langerhans-cell histiocytosis	0.010	0.989	0.000
C96.4 Sarcoma of dendritic cells (accessory cells)	0.010	0.989	0.000
C96.3 True histiocytic lymphoma	0.010	0.989	0.000
C96.2 Malignant mast cell tumour	0.010	0.989	0.000
C96.1 Malignant histiocytosis	0.010	0.989	0.000
C96.0 Letterer-Siwe disease	0.010	0.989	0.000
H81.1 Benign paroxysmal vertigo	0.010	0.989	0.000
C82.1 Mixed small cleaved and large cell, follicular	0.010	0.989	0.000
H62.8 Other disorders of external ear in diseases classified elsewhere	0.010	0.990	0.000
H62.4 Otitis externa in other diseases classified elsewhere	0.010	0.990	0.000
H62.3 Otitis externa in other infectious and parasitic diseases classified elsewhere	0.010	0.990	0.000
H62.2 Otitis externa in mycoses	0.010	0.990	0.000
H62.1 Otitis externa in viral diseases classified elsewhere	0.010	0.990	0.000
H62.0 Otitis externa in bacterial diseases classified elsewhere	0.010	0.990	0.000
H61.0 Perichondritis of external ear	0.010	0.990	0.000
C81.1 Nodular sclerosis	0.010	0.990	0.000
H93 Other disorders of ear, not elsewhere classified	0.010	0.990	0.000
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified	0.009	0.990	0.000
S83.2 Tear of meniscus, current	0.000	0.991	0.009
H81.8 Other disorders of vestibular function	0.009	0.991	0.000
H81.4 Vertigo of central origin	0.009	0.991	0.000
H81.3 Other peripheral vertigo	0.009	0.991	0.000
C84.9 Mature T/NK-cell lymphoma, unspecified	0.009	0.991	0.000
C84.8 Cutaneous T-cell lymphoma, unspecified	0.009	0.991	0.000
C84.7 Anaplastic large cell lymphoma, ALK-negative	0.009	0.991	0.000
C84.6 Anaplastic large cell lymphoma, ALK-positive	0.009	0.991	0.000
C84.3 Lymphoepithelioid lymphoma	0.009	0.991	0.000
C84.2 T-zone lymphoma	0.009	0.991	0.000
C84.1 Sezary's diease	0.009	0.991	0.000
C84.0 Mycosis fungoides	0.009	0.991	0.000
C90 Multiple myeloma and malignant plasma cell neoplasms	0.009	0.991	0.000
C84.4 Peripheral T-cell lymphoma	0.009	0.991	0.000
H83 Other diseases of inner ear	0.009	0.991	0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee	0.000	0.991	0.009
H69.9 Eustachian tube disorder, unspecified	0.008	0.991	0.001
H81.9 Disorder of vestibular function, unspecified	0.009	0.991	0.000
H94 Other disorders of ear in diseases classified elsewhere	0.009	0.991	0.000
S83.6 Sprain and strain of other and unspecified parts of knee	0.000	0.991	0.008
H81.0 Meniere's disease	0.008	0.992	0.000
H93.9 Disorder of ear, unspecified	0.008	0.992	0.000
H93.8 Other specified disorders of ear	0.008	0.992	0.000
H93.3 Disorders of acoustic nerve	0.008	0.992	0.000
H95.1 Other disorders following mastoidectomy	0.008	0.992	0.000
H65.3 Chronic mucoid otitis media	0.008	0.992	0.000
C84.5 Other and unspecified T-cell lymphomas	0.008	0.992	0.000
H80.8 Other otosclerosis	0.008	0.992	0.000
H80.2 Cochlear otosclerosis	0.008	0.992	0.000
H80.1 Otosclerosis involving oval window, obliterative	0.008	0.992	0.000
H80.0 Otosclerosis involving oval window, nonobliterative	0.008	0.992	0.000
S82.20 Fracture of shaft of tibia (closed)	0.000	0.992	0.008
H90 Conductive and sensorineural hearing loss	0.008	0.992	0.000
J98.4 Other disorders of lung	0.008	0.992	0.000
K50.9 Crohn's disease, unspecified	0.000	0.993	0.007
S80 Superficial injury of lower leg	0.000	0.993	0.007
H80.9 Otosclerosis, unspecified	0.007	0.993	0.000
S80.8 Other superficial injuries of lower leg	0.000	0.993	0.007
H92 Otalgia and effusion of ear	0.007	0.993	0.000
S80-S89 Injuries to the knee and lower leg	0.000	0.993	0.007
S83.5 Sprain and strain involving (anterior)(posterior) cruciate ligament of knee	0.000	0.993	0.007
H93.2 Other abnormal auditory perceptions	0.007	0.993	0.000
H93.0 Degenerative and vascular disorders of ear	0.007	0.993	0.000
H95.9 Postprocedural disorder of ear and mastoid process, unspecified	0.007	0.993	0.000
H95.8 Other postprocedural disorders of ear and mastoid process	0.007	0.993	0.000
H95.0 Recurrent cholesteatoma of postmastoidectomy cavity	0.007	0.993	0.000
C90.3 Solitary plasmacytoma	0.007	0.993	0.000
C90.1 Plasma cell leukaemia	0.007	0.993	0.000
S83.7 Injury to multiple structures of knee	0.000	0.993	0.007
S83.4 Sprain and strain involving (fibular)(tibial) collateral ligamnent of knee	0.000	0.993	0.007
S83.3 Tear of articular cartilage of knee, current	0.000	0.993	0.007
S83.1 Dislocation of knee	0.000	0.993	0.007
S83.0 Dislocation of patella	0.000	0.993	0.007
H83.9 Disease of inner ear, unspecified	0.007	0.993	0.000
H83.8 Other specified diseases of inner ear	0.007	0.993	0.000
H83.3 Noise effects on inner ear	0.007	0.993	0.000
H83.2 Labyrinthine dysfunction	0.007	0.993	0.000
H83.1 Labyrinthine fistula	0.007	0.993	0.000
H40.9 Glaucoma, unspecified	0.007	0.993	0.000
S89 Other and unspecified injuries of lower leg	0.000	0.993	0.006
H94.8 Other specified disorders of ear in diseases classified elsewhere	0.006	0.993	0.000
H94.0 Acoustic neuritis in infectious and parasitic diseases classified elsewhere	0.006	0.993	0.000
S82.2 Fracture of shaft of tibia	0.000	0.994	0.006
S80.0 Contusion of knee	0.000	0.994	0.006
H90.4 Sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side	0.006	0.994	0.000
S89.9 Unspecified injury of lower leg	0.000	0.994	0.006
H90.3 Sensorineural hearing loss, bilateral	0.006	0.994	0.000
H92.1 Otorrhoea	0.006	0.994	0.000
H90.6 Mixed conductive and sensorineural hearing loss, bilateral	0.006	0.994	0.000
S80.1 Contusion of other and unspecified parts of lower leg	0.000	0.994	0.006
C90.2 Plasmacytoma, extramedullary	0.006	0.994	0.000
S82 Fracture of lower leg, including ankle	0.000	0.994	0.006
H90.8 Mixed conductive and sensorineural hearing loss, unspecified	0.006	0.994	0.000
H90.7 Mixed conductive and sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side	0.006	0.994	0.000
H91 Other hearing loss	0.006	0.994	0.000
H90.5 Sensorineural hearing loss, unspecified	0.006	0.994	0.000
S80.7 Multiple superficial injuries of lower leg	0.000	0.994	0.005
H92.2 Otorrhagia	0.005	0.994	0.000
S88 Traumatic amputation of lower leg	0.000	0.994	0.005
S87 Crushing injury of lower leg	0.000	0.994	0.005
S85 Injury of blood vessels at lower leg level	0.000	0.994	0.005
S84 Injury of nerves at lower leg level	0.000	0.994	0.005
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency	0.000	0.994	0.005
S86 Injury of muscle and tendon at lower leg level	0.000	0.995	0.005
S82.4 Fracture of fibula alone	0.000	0.995	0.005
H90.1 Conductive hearing loss, unilateral with unrestricted hearing on the contralateral side	0.005	0.995	0.000
S89.7 Multiple injuries of lower leg	0.000	0.995	0.005
S89.1 Other specified injuries of lower leg	0.000	0.995	0.005
S89.0 Multiple injuries of lower leg	0.000	0.995	0.005
S82.40 Fracture of fibula alone (closed)	0.000	0.995	0.005
H83.0 Labyrinthitis	0.005	0.995	0.000
H90.0 Conductive hearing loss, bilateral	0.005	0.995	0.000
S81 Open wound of lower leg	0.000	0.995	0.005
H91.3 Deaf mutism, not elsewhere classified	0.005	0.995	0.000
S80.9 Superficial injury of lower leg, unspecified	0.000	0.995	0.004
S89.8 Other specified injuries of lower leg	0.000	0.995	0.004
S82.9 Fracture of lower leg, part unspecified	0.000	0.996	0.004
S82.21 Fracture of shaft of tibia (open)	0.000	0.996	0.004
C19 Malignant neoplasm of rectosigmoid junction	0.004	0.996	0.000
M67.8 Other specified disorders of synovium and tendon	0.000	0.996	0.004
H91.2 Sudden idiopathic hearing loss	0.004	0.996	0.000
H91.1 Presbycusis	0.004	0.996	0.000
H91.0 Ototoxic hearing loss	0.004	0.996	0.000
S81.0 Open wound of knee	0.000	0.996	0.004
S82.5 Fracture of medial malleolus	0.000	0.996	0.004
S84.9 Injury of unspecified nerve at lower leg level	0.000	0.996	0.004
S84.8 Injury of other nerves at lower leg level	0.000	0.996	0.004
S84.7 Injury of multiple nerves at lower leg level	0.000	0.996	0.004
S84.2 Injury of cutaneous sensory nerve at lower leg level	0.000	0.996	0.004
S84.1 Injury of peroneal nerve at lower leg level	0.000	0.996	0.004
S84.0 Injury of tibial nerve at lower leg level	0.000	0.996	0.004
S85.9 Injury of unspecified blood vessel at lower leg level	0.000	0.996	0.004
S85.8 Injury of other blood vessels at lower leg level	0.000	0.996	0.004
S85.7 Injury of multiple blood vessels at lower leg level	0.000	0.996	0.004
S85.5 Injury of popliteal vein	0.000	0.996	0.004
S85.4 Injury of lesser saphenous vein at lower leg level	0.000	0.996	0.004
S85.3 Injury of greater saphenous vein at lower leg level	0.000	0.996	0.004
S85.2 Injury of peroneal artery	0.000	0.996	0.004
S85.1 Injury of (anterior)(posterior) tibial artery	0.000	0.996	0.004
S85.0 Injury of popliteal artery	0.000	0.996	0.004
S87.8 Crushing injury of other and unspecified parts of lower leg	0.000	0.996	0.004
S87.0 Crushing injury of knee	0.000	0.996	0.004
S88.9 Traumatic amputation of lower leg, level unspecified	0.000	0.996	0.004
S88.1 Traumatic amputation at level between knee and ankle	0.000	0.996	0.004
S88.0 Traumatic amputation at knee level	0.000	0.996	0.004
S82.8 Fractures of other parts of lower leg	0.000	0.996	0.004
S86.0 Injury of Achilles tendon	0.000	0.996	0.004
S86.8 Injury of other muscles and tendons at lower leg level	0.000	0.996	0.004
S86.7 Injury of multiple muscles and tendons at lower leg level	0.000	0.996	0.004
S86.3 Injury of muscle(s) and tendon(s) of peroneal muscle group at lower leg level	0.000	0.996	0.004
S86.2 Injury of muscle(s) and tendon(s) of anterior muscle group at lower leg level	0.000	0.996	0.004
S86.1 Injury of other muscle(s) and tendon(s) of posterior muscle group at lower leg level	0.000	0.996	0.004
S82.1 Fracture of upper end of tibia	0.000	0.996	0.004
S82.41 Fracture of fibula alone (open)	0.000	0.996	0.004
H90.2 Conductive hearing loss, unspecified	0.004	0.996	0.000
S82.0 Fracture of patella	0.000	0.996	0.004
S86.9 Injury of unspecified muscle and tendon at lower leg level	0.000	0.996	0.004
S82.7 Multiple fractures of lower leg	0.000	0.996	0.004
C90.0 Multiple myeloma	0.004	0.996	0.000
S82.80 Fractures of other parts of lower leg (closed)	0.000	0.996	0.004
H91.8 Other specified hearing loss	0.003	0.996	0.000
S81.7 Multiple open wounds of lower leg	0.000	0.996	0.003
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.000	0.996	0.004
O42.0 Premature rupture of membranes, onset of labour within 24 hours	0.000	0.996	0.004
H40.0 Glaucoma suspect	0.004	0.996	0.000
S82.91 Fracture of lower leg, part unspecified (open)	0.000	0.997	0.003
S82.90 Fracture of lower leg, part unspecified (closed)	0.000	0.997	0.003
H40 Glaucoma	0.003	0.997	0.000
S82.51 Fracture of medial malleolus (open)	0.000	0.997	0.003
H40.5 Glaucoma secondary to other eye disorders	0.003	0.997	0.000
S82.86 Maisonneuve's fracture	0.000	0.997	0.003
H92.0 Otalgia	0.003	0.997	0.000
S86.00 Unspecified injury of Achilles tendon	0.000	0.997	0.003
H93.1 Tinnitus	0.003	0.997	0.000
S82.11 Fracture of upper end of tibia (open)	0.000	0.997	0.003
N50.1 Vascular disorders of male genital organs	0.000	0.997	0.003
S82.50 Fracture of medial malleolus (closed)	0.000	0.997	0.003
S82.6 Fracture of lateral malleolus	0.000	0.997	0.003
Q38.7 Pharyngeal pouch	0.003	0.997	0.000
R68.8 Other specified general symptoms and signs	0.003	0.997	0.000
S82.01 Fracture of patella (open)	0.000	0.997	0.003
S82.71 Multiple fractures of lower leg (open)	0.000	0.997	0.003
H40.4 Glaucoma secondary to eye inflammation	0.003	0.997	0.000
S82.3 Fracture of lower end of tibia	0.000	0.997	0.003
I05.9 Mitral valve disease, unspecified	0.000	0.997	0.003
S82.10 Fracture of upper end of tibia (closed)	0.000	0.997	0.003
R22.1 Localised swelling, mass and lump, neck	0.000	0.997	0.003
H40.6 Glaucoma secondary to drugs	0.003	0.997	0.000
H40.3 Glaucoma secondary to eye trauma	0.003	0.997	0.000
D46.7 Other myelodysplastic syndromes	0.003	0.997	0.000
S81.8 Open wound of other parts of lower leg	0.000	0.997	0.003
S82.70 Multiple fractures of lower leg (closed)	0.000	0.997	0.002
S82.00 Fracture of patella (closed)	0.000	0.997	0.002
K50.1 Crohn's disease of large intestine	0.000	0.997	0.003
N30.0 Acute cystitis	0.000	0.997	0.003
M67 Other disorders of synovium and tendon	0.000	0.997	0.003
S81.9 Open wound of lower leg, part unspecified	0.000	0.997	0.002
S82.61 Fracture of lateral malleolus (open)	0.000	0.997	0.002
K50 Crohn's disease [regional enteritis]	0.000	0.997	0.002
O42 Premature rupture of membranes	0.000	0.997	0.003
T39.1 4-Aminophenol derivatives	0.000	0.997	0.003
D46 Myelodysplastic syndromes	0.002	0.998	0.000
Z01.4 Gynaecological examination (general)(routine)	0.000	0.998	0.002
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.000	0.998	0.002
S82.81 Fractures of other parts of lower leg (open)	0.001	0.998	0.002
M67.2 Synovial hypertrophy, not elsewhere classified	0.000	0.998	0.002
W19.4 Street and highway	0.000	0.998	0.002
O42.9 Premature rupture of membranes, unspecified	0.000	0.998	0.002
O42.1 Premature rupture of membranes, onset of labour after 24 hours	0.000	0.998	0.002
D86.0 Sarcoidosis of lung	0.002	0.998	0.000
T39.0 Salicylates	0.000	0.998	0.002
D25.2 Subserosal leiomyoma of uterus	0.002	0.998	0.000
D44.3 Pituitary gland	0.002	0.998	0.000
D51 Vitamin B12 deficiency anaemia	0.000	0.998	0.002
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands	0.002	0.998	0.000
Z01.9 Special examination, unspecified	0.000	0.998	0.002
D46.2 Refractory anaemia with excess of blasts	0.002	0.998	0.000
E14.3 With ophthalmic complications	0.000	0.998	0.002
S00.9 Superficial injury of head, part unspecified	0.000	0.998	0.002
H40.8 Other glaucoma	0.002	0.998	0.000
M67.9 Disorder of synovium and tendon, unspecified	0.000	0.998	0.002
M67.4 Ganglion	0.000	0.998	0.002
M67.3 Transient synovitis	0.000	0.998	0.002
M67.0 Short Achilles tendon (acquired)	0.000	0.998	0.002
C09.9 Tonsil, unspecified	0.002	0.998	0.000
K37 Unspecified appendicitis	0.002	0.998	0.000
C56 Malignant neoplasm of ovary	0.002	0.998	0.000
O42.2 Premature rupture of membranes, labour delayed by therapy	0.000	0.998	0.002
V18.2 Unspecified pedal cyclist injured in nontraffic accident	0.002	0.998	0.000
D44.4 Craniopharyngeal duct	0.002	0.998	0.000
S82.31 Fracture of lower end of tibia (open)	0.000	0.998	0.002
M67.1 Other contracture of tendon (sheath)	0.000	0.998	0.002
D46.9 Myelodysplastic syndrome, unspecified	0.002	0.998	0.000
D46.6 Myelodysplastic syndrome with isolated del(5q) chromosomal abnormality	0.002	0.998	0.000
D46.5 Refractory anaemia with multi-lineage dysplasia	0.002	0.998	0.000
D46.4 Refractory anaemia, unspecified	0.002	0.998	0.000
D46.3 Refractory anaemia with excess of blasts with transformation	0.002	0.998	0.000
D46.1 Refractory anaemia with sideroblasts	0.002	0.998	0.000
D46.0 Refractory anaemia without sideroblasts, so stated	0.002	0.998	0.000
J38.7 Other diseases of larynx	0.002	0.998	0.000
K85.1 Biliary acute pancreatitis	0.002	0.998	0.000
Q38 Other congenital malformations of tongue, mouth and pharynx	0.002	0.998	0.000
T39.4 Antirheumatics, not elsewhere classified	0.000	0.998	0.002
T39.2 Pyrazolone derivatives	0.000	0.998	0.002
Z48.0 Attention to surgical dressings and sutures	0.002	0.998	0.000
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)	0.002	0.998	0.000
D44.8 Pluriglandular involvement	0.002	0.998	0.000
D47.1 Chronic myeloproliferative disease	0.002	0.998	0.000
D38.1 Trachea, bronchus and lung	0.002	0.998	0.000
K80.0 Calculus of gallbladder with acute cholecystitis	0.002	0.998	0.000
D37-D48 Neoplasms of uncertain or unknown behaviour	0.002	0.998	0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs	0.002	0.998	0.000
C49.3 Connective and soft tissue of thorax	0.002	0.998	0.000
C53.0 Endocervix	0.002	0.998	0.000
K50.0 Crohn's disease of small intestine	0.002	0.998	0.000
S72.10 Pertrochanteric fracture (closed)	0.002	0.998	0.000
D07.5 Prostate	0.000	0.998	0.002
D51.8 Other vitamin B12 deficiency anaemias	0.000	0.998	0.002
D51.3 Other dietary vitamin B12 deficiency anaemia	0.000	0.998	0.002
D51.2 Transcobalamin II deficiency	0.000	0.998	0.002
D51.1 Vitamin B12 deficiency anaemia due to selective vitamin B12 malabsorption with proteinuria	0.000	0.998	0.002
C97 Malignant neoplasms of independent (primary) multiple sites	0.002	0.998	0.000
C51-C58 Malignant neoplasms of female genital organs	0.002	0.998	0.000
C51.9 Vulva, unspecified	0.002	0.998	0.000
C09 Malignant neoplasm of tonsil	0.002	0.998	0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs	0.002	0.998	0.000
I05 Rheumatic mitral valve diseases	0.000	0.998	0.002
D44.9 Endocrine gland, unspecified	0.002	0.998	0.000
D44.7 Aortic body and other paraganglia	0.002	0.998	0.000
D44.6 Carotid body	0.002	0.998	0.000
D44.5 Pineal gland	0.002	0.998	0.000
D44.2 Parathyroid gland	0.002	0.998	0.000
D44.1 Adrenal gland	0.002	0.998	0.000
D44.0 Thyroid gland	0.002	0.998	0.000
C51 Malignant neoplasm of vulva	0.002	0.998	0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.002	0.998	0.000
M07.39 Other psoriatic arthropathies (Site unspecified)	0.002	0.998	0.000
C41.9 Bone and articular cartilage, unspecified	0.002	0.998	0.000
M54.64 Pain in thoracic spine (Thoracic region)	0.000	0.998	0.002
C53 Malignant neoplasm of cervix uteri	0.002	0.998	0.000
C17.9 Small intestine, unspecified	0.002	0.998	0.000
I05.1 Rheumatic mitral insufficiency	0.000	0.998	0.002
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.002	0.998	0.000
M67.49 Ganglion, multiple sites	0.000	0.998	0.002
M67.47 Ganglion, ankle and foot	0.000	0.998	0.002
M67.45 Ganglion, hip	0.000	0.998	0.002
M67.43 Ganglion, wrist	0.000	0.998	0.002
M67.96 Unspecified disorder of synovium and tendon, lower leg	0.000	0.998	0.002
D40.1 Testis	0.002	0.998	0.000
C15-C26 Malignant neoplasms of digestive organs	0.002	0.998	0.000
D47.3 Essential (haemorrhagic) thrombocythaemia	0.002	0.998	0.000
K80.1 Calculus of gallbladder with other cholecystitis	0.002	0.998	0.000
C41 Malignant neoplasm of bone and articular cartilage of other and unspecified sites	0.002	0.998	0.000
I05.0 Mitral stenosis	0.000	0.998	0.002
C40-C41 Malignant neoplasms of bone and articular cartilage	0.002	0.998	0.000
Chapter II Neoplasms	0.002	0.998	0.000
Z01.8 Other specified special examinations	0.000	0.998	0.002
Z01.7 Laboratory examination	0.000	0.998	0.002
Z99.1 Dependence on respirator	0.002	0.998	0.000
C17 Malignant neoplasm of small intestine	0.002	0.998	0.000
C50.3 Lower-inner quadrant of breast	0.002	0.998	0.000
C64 Malignant neoplasm of kidney, except renal pelvis	0.002	0.998	0.000
Z01 Other special examinations and investigations of persons without complaint or reported diagnosis	0.000	0.998	0.002
K05.3 Chronic periodontitis	0.002	0.998	0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.000	0.998	0.002
D45 Polycythaemia vera	0.002	0.998	0.000
N02.9 Unspecified	0.000	0.998	0.002
Q38.8 Other congenital malformations of pharynx	0.002	0.998	0.000
Q38.6 Other congenital malformations of mouth	0.002	0.998	0.000
Q38.5 Congenital malformations of palate, not elsewhere classified	0.002	0.998	0.000
Q38.4 Congenital malformations of salivary glands and ducts	0.002	0.998	0.000
Q38.3 Other congenital malformations of tongue	0.002	0.998	0.000
Q38.2 Macroglossia	0.002	0.998	0.000
Q38.1 Ankyloglossia	0.002	0.998	0.000
Q38.0 Congenital malformations of lips, not elsewhere classified	0.002	0.998	0.000
C49 Malignant neoplasm of other connective and soft tissue	0.002	0.998	0.000
D40.0 Prostate	0.002	0.998	0.000
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes	0.002	0.998	0.000
C57 Malignant neoplasm of other and unspecified female genital organs	0.002	0.998	0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges	0.002	0.998	0.000
R68 Other general symptoms and signs	0.002	0.998	0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.002	0.998	0.000
S82.30 Fracture of lower end of tibia (closed)	0.000	0.998	0.001
D38.6 Respiratory organ, unspecified	0.001	0.998	0.000
D38.5 Other respiratory organs	0.001	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations