TreeWAS – Variant ID: rs476633

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
I25.1 Atherosclerotic heart disease	0.163	0.837	0.000
I10 Essential (primary) hypertension	0.035	0.965	0.000
I77.9 Disorder of arteries and arterioles, unspecified	0.000	0.982	0.018
N30.9 Cystitis, unspecified	0.014	0.986	0.000
I10-I15 Hypertensive diseases	0.014	0.986	0.000
I15 Secondary hypertension	0.012	0.988	0.000
I15.9 Seconday hypertension, unspecified	0.011	0.989	0.000
I13 Hypertensive heart and renal disease	0.010	0.990	0.000
I15.0 Renovascular hypertension	0.010	0.990	0.000
I15.8 Other secondary hypertension	0.009	0.991	0.000
I15.2 Hypertension secondary to endocrine disorders	0.009	0.991	0.000
I15.1 Hypertension secondary to other renal disorders	0.009	0.991	0.000
I08.0 Disorders of both mitral and aortic valves	0.009	0.991	0.000
I12 Hypertensive renal disease	0.009	0.991	0.000
N18.9 Chronic renal failure, unspecified	0.008	0.992	0.000
I12.9 Hypertensive renal disease without renal failure	0.008	0.992	0.000
I13.9 Hypertensive heart and renal disease, unspecified	0.008	0.992	0.000
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure	0.008	0.992	0.000
I13.1 Hypertensive heart and renal disease with renal failure	0.008	0.992	0.000
I13.0 Hypertensive heart and renal disease with (congestive) heart failure	0.008	0.992	0.000
I08.3 Combined disorders of mitral, aortic and tricuspid valves	0.007	0.993	0.000
N30 Cystitis	0.007	0.993	0.000
N18.3 Chronic kidney disease, stage 3	0.007	0.993	0.000
I08 Multiple valve diseases	0.007	0.993	0.000
N30.3 Trigonitis	0.007	0.993	0.000
C79.2 Secondary malignant neoplasm of skin	0.000	0.993	0.007
N30.1 Interstitial cystitis (chronic)	0.006	0.994	0.000
I08.9 Multiple valve disease, unspecified	0.006	0.994	0.000
I08.8 Other multiple valve diseases	0.006	0.994	0.000
N30.2 Other chronic cystitis	0.006	0.994	0.000
I11 Hypertensive heart disease	0.005	0.994	0.001
K50.1 Crohn's disease of large intestine	0.006	0.994	0.000
N18 Chronic renal failure	0.006	0.994	0.000
T84.5 Infection and inflammatory reaction due to internal joint prosthesis	0.000	0.995	0.005
S72.40 Fracture of lower end of femur (closed)	0.005	0.995	0.000
I72.4 Aneurysm of artery of lower extremity	0.000	0.995	0.005
R16.1 Splenomegaly, not elsewhere classified	0.000	0.995	0.005
N30.4 Irradiation cystitis	0.005	0.995	0.000
I08.2 Disorders of both aortic and tricuspid valves	0.005	0.995	0.000
N18.5 Chronic kidney disease, stage 5	0.005	0.995	0.000
N18.1 Chronic kidney disease, stage 1	0.005	0.995	0.000
O20.9 Haemorrhage in early pregnancy, unspecified	0.005	0.995	0.000
S72.41 Fracture of lower end of femur (open)	0.004	0.995	0.000
S72.4 Fracture of lower end of femur	0.004	0.996	0.000
I72 Other aneurysm	0.000	0.996	0.004
K74.5 Biliary cirrhosis, unspecified	0.000	0.996	0.004
N18.8 Other chronic renal failure	0.004	0.996	0.000
N30.0 Acute cystitis	0.004	0.996	0.000
I72.9 Aneurysm of unspecified site	0.000	0.996	0.004
K14.0 Glossitis	0.004	0.996	0.000
I72.8 Aneurysm of other specified arteries	0.000	0.996	0.004
H02.6 Xanthelasma of eyelid	0.000	0.996	0.004
K74.3 Primary biliary cirrhosis	0.000	0.996	0.004
C34.1 Upper lobe, bronchus or lung	0.000	0.996	0.004
N18.2 Chronic kidney disease, stage 2	0.004	0.996	0.000
C56 Malignant neoplasm of ovary	0.000	0.996	0.004
N18.0 End-stage renal disease	0.004	0.996	0.000
O68.2 Labour and delivery complicated by foetal heart rate anomaly with meconium in amniotic fluid	0.004	0.996	0.000
I11.0 Hypertensive heart disease with (congestive) heart failure	0.003	0.996	0.001
I72.2 Aneurysm of renal artery	0.000	0.996	0.004
I72.0 Aneurysm of carotid artery	0.000	0.996	0.004
K74 Fibrosis and cirrhosis of liver	0.000	0.996	0.004
S42.40 Fracture of lower end of humerus (closed)	0.000	0.997	0.003
I72.6 Aneurysm and dissection of vertebral artery	0.000	0.997	0.003
I72.5 Aneurysm and dissection of other precerebral arteries	0.000	0.997	0.003
H50.0 Convergent concomitant strabismus	0.000	0.997	0.003
I72.1 Aneurysm of artery of upper extremity	0.000	0.997	0.003
H02.0 Entropion and trichiasis of eyelid	0.000	0.997	0.003
K74.0 Hepatic fibrosis	0.000	0.997	0.003
I72.3 Aneurysm of iliac artery	0.000	0.997	0.003
S02.50 Fracture of tooth (closed)	0.000	0.997	0.003
K74.4 Secondary biliary cirrhosis	0.000	0.997	0.003
K74.2 Hepatic fibrosis with hepatic sclerosis	0.000	0.997	0.003
K80.8 Other cholelithiasis	0.003	0.997	0.000
K74.6 Other and unspecified cirrhosis of liver	0.000	0.997	0.003
S72.20 Subtrochanteric fracture (closed)	0.003	0.997	0.000
G50.0 Trigeminal neuralgia	0.000	0.997	0.003
K74.1 Hepatic sclerosis	0.000	0.997	0.003
E85.9 Amyloidosis, unspecified	0.003	0.997	0.000
J84.1 Other interstitial pulmonary diseases with fibrosis	0.000	0.997	0.003
L43.9 Lichen planus, unspecified	0.003	0.997	0.000
I11.9 Hypertensive heart disease without (congestive) heart failure	0.001	0.997	0.001
M23.32 Other meniscus derangements (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.000	0.997	0.003
R16 Hepatomegaly and splenomegaly, not elsewhere classified	0.000	0.998	0.002
T85.4 Mechanical complication of breast prosthesis and implant	0.002	0.998	0.000
I62.9 Intracranial haemorrhage (nontraumatic), unspecified	0.002	0.998	0.000
R16.2 Hepatomegaly with splenomegaly, not elsewhere classified	0.000	0.998	0.002
S72.2 Subtrochanteric fracture	0.002	0.998	0.000
Z39.2 Routine postpartum follow-up	0.002	0.998	0.000
J00 Acute nasopharyngitis [common cold]	0.000	0.998	0.002
H02.1 Ectropion of eyelid	0.000	0.998	0.002
N13.8 Other obstructive and reflux uropathy	0.000	0.998	0.002
Q50.4 Embryonic cyst of Fallopian tube	0.000	0.998	0.002
C50.5 Lower-outer quadrant of breast	0.000	0.998	0.002
Z39.0 Care and examination immediately after delivery	0.002	0.998	0.000
D16.3 Short bones of lower limb	0.000	0.998	0.002
N42.9 Disorder of prostate, unspecified	0.002	0.998	0.000
H02.9 Disorder of eyelid, unspecified	0.000	0.998	0.002
H02 Other disorders of eyelid	0.000	0.998	0.002
N18.4 Chronic kidney disease, stage 4	0.002	0.998	0.000
X78.0 Home	0.002	0.998	0.000
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency	0.002	0.998	0.000
I09.9 Rheumatic heart disease, unspecified	0.002	0.998	0.000
E85.4 Organ-limited amyloidosis	0.002	0.998	0.000
Z29.1 Prophylactic immunotherapy	0.002	0.998	0.000
M62.80 Other specified disorders of muscle (Multiple sites)	0.002	0.998	0.000
Z92.8 Personal history of other medical treatment	0.002	0.998	0.000
I09 Other rheumatic heart diseases	0.002	0.998	0.000
S72 Fracture of femur	0.002	0.998	0.000
S02.10 Fracture of base of skull (closed)	0.000	0.998	0.002
H53.1 Subjective visual disturbances	0.002	0.998	0.000
I05-I09 Chronic rheumatic heart diseases	0.002	0.998	0.000
S72.21 Subtrochanteric fracture (open)	0.002	0.998	0.000
T17.2 Foreign body in pharynx	0.002	0.998	0.000
H02.2 Lagophthalmos	0.000	0.998	0.002
M25.94 Joint disorder, unspecified (Hand)	0.000	0.998	0.002
E85.3 Secondary systemic amyloidosis	0.002	0.998	0.000
E85 Amyloidosis	0.002	0.998	0.000
H02.5 Other disorders affecting eyelid function	0.000	0.998	0.002
T18.1 Foreign body in oesophagus	0.002	0.998	0.000
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms	0.000	0.998	0.002
H54.0 Blindness, both eyes	0.000	0.998	0.002
O63.0 Prolonged first stage (of labour)	0.000	0.998	0.002
K76.6 Portal hypertension	0.000	0.998	0.002
S86.8 Injury of other muscles and tendons at lower leg level	0.002	0.998	0.000
Q50.5 Embryonic cyst of broad ligament	0.000	0.998	0.002
L93.0 Discoid lupus erythematosus	0.002	0.998	0.000
D86.9 Sarcoidosis, unspecified	0.002	0.998	0.000
G43.1 Migraine with aura [classical migraine]	0.002	0.998	0.000
S72.9 Fracture of femur, part unspecified	0.002	0.998	0.000
T14.0 Superficial injury of unspecified body region	0.002	0.998	0.000
Z39 Postpartum care and examination	0.002	0.998	0.000
I12.0 Hypertensive renal disease with renal failure	0.002	0.998	0.000
S72.3 Fracture of shaft of femur	0.002	0.998	0.000
I09.8 Other specified rheumatic heart diseases	0.001	0.998	0.000
I09.2 Chronic rheumatic pericarditis	0.001	0.998	0.000
I09.1 Rheumatic diseases of endocardium, valve unspecified	0.001	0.998	0.000
I09.0 Rheumatic myocarditis	0.001	0.998	0.000
R16.0 Hepatomegaly, not elsewhere classified	0.000	0.998	0.002
M82.11 Osteoporosis in endocrine disorders (Shoulder region)	0.000	0.998	0.002
S72.7 Multiple fractures of femur	0.002	0.998	0.000
L89.0 Stage I decubitus ulcer and pressure area	0.000	0.998	0.002
M43.17 Spondylolisthesis (Lumbosacral region)	0.000	0.998	0.002
S72.31 Fracture of shaft of femur (open)	0.002	0.998	0.000
E85.2 Heredofamilial amyloidosis, unspecified	0.001	0.998	0.000
E85.1 Neuropathic heredofamilial amyloidosis	0.001	0.998	0.000
E85.0 Nonneuropathic heredofamilial amyloidosis	0.001	0.998	0.000
H02.7 Other degenerative disorders of eyelid and periocular area	0.000	0.998	0.001
Y60.4 During endoscopic examination	0.002	0.998	0.000
M25.68 Stiffness of joint, not elsewhere classified (Other)	0.000	0.998	0.002
M53.38 Sacrococcygeal disorders, not elsewhere classified-Sacral/s	0.002	0.998	0.000
D86.3 Sarcoidosis of skin	0.002	0.998	0.000
J92.9 Pleural plaque without asbestos	0.000	0.998	0.002
Q50 Congenital malformations of ovaries, Fallopian tubes and broad ligaments	0.000	0.998	0.002
S72.90 Fracture of femur, part unspecified (closed)	0.001	0.998	0.000
D86.0 Sarcoidosis of lung	0.002	0.998	0.000
N30.8 Other cystitis	0.002	0.998	0.000
M82.10 Osteoporosis in endocrine disorders (Multiple sites)	0.000	0.998	0.002
I06 Rheumatic aortic valve diseases	0.001	0.998	0.000
N99.4 Postprocedural pelvic peritoneal adhesions	0.002	0.998	0.000
G83.1 Monoplegia of lower limb	0.000	0.998	0.001
S72.8 Fractures of other parts of femur	0.001	0.998	0.000
G50 Disorders of trigeminal nerve	0.000	0.998	0.002
S72.91 Fracture of femur, part unspecified (open)	0.001	0.998	0.000
G50.1 Atypical facial pain	0.000	0.998	0.001
G83.8 Other specified paralytic syndromes	0.000	0.998	0.001
S01.4 Open wound of cheek and temporomandibular area	0.000	0.998	0.002
S31.1 Open wound of abdominal wall	0.001	0.998	0.000
S62.50 Fracture of thumb (closed)	0.001	0.998	0.000
E85.8 Other amyloidosis	0.001	0.998	0.000
B00.9 Herpesviral infection, unspecified	0.001	0.999	0.000
Z39.1 Care and examination of lactating mother	0.001	0.999	0.000
S72.71 Multiple fractures of femur (open)	0.001	0.999	0.000
S72.70 Multiple fractures of femur (closed)	0.001	0.999	0.000
G83.9 Paralytic syndrome, unspecified	0.000	0.999	0.001
I06.9 Rheumatic aortic valve disease, unspecified	0.001	0.999	0.000
G50.8 Other disorders of trigeminal nerve	0.000	0.999	0.001
N42.1 Congestion and haemorrhage of prostate	0.001	0.999	0.000
H60.9 Otitis externa, unspecified	0.000	0.999	0.001
I89.0 Lymphoedema, not elsewhere classified	0.001	0.999	0.000
Q23.1 Congenital insufficiency of aortic valve	0.000	0.999	0.001
R23.4 Changes in skin texture	0.000	0.999	0.001
D26.1 Corpus uteri	0.001	0.999	0.000
Q50.6 Other congenital malformatons of Fallopian tube and broad ligament	0.000	0.999	0.001
Q50.3 Other congenital malformations of ovary	0.000	0.999	0.001
Q50.2 Congenital torsion of ovary	0.000	0.999	0.001
Q50.1 Developmental ovarian cyst	0.000	0.999	0.001
Q50.0 Congenital absence of ovary	0.000	0.999	0.001
Z57.5 Occupational exposure to toxic agents in other industries	0.000	0.999	0.001
D86 Sarcoidosis	0.001	0.999	0.000
M25.66 Stiffness of joint, not elsewhere classified (Lower leg)	0.000	0.999	0.001
S72.30 Fracture of shaft of femur (closed)	0.001	0.999	0.000
I06.8 Other rheumatic aortic valve diseases	0.001	0.999	0.000
I06.2 Rheumatic aortic stenosis with insufficiency	0.001	0.999	0.000
S02.5 Fracture of tooth	0.000	0.999	0.001
J84 Other interstitial pulmonary diseases	0.000	0.999	0.001
K91.4 Colostomy and enterostomy malfunction	0.000	0.999	0.001
Y42.5 Other oestrogens and progestogens	0.001	0.999	0.000
S72.81 Fractures of other parts of femur (open)	0.001	0.999	0.000
F52.2 Failure of genital response	0.001	0.999	0.000
H54.7 Unspecified visual loss	0.000	0.999	0.001
J32.2 Chronic ethmoidal sinusitis	0.000	0.999	0.001
M82.1 Osteoporosis in endocrine disorders	0.000	0.999	0.001
D59.1 Other autoimmune haemolytic anaemias	0.000	0.999	0.001
D86.8 Sarcoidosis of other and combined sites	0.001	0.999	0.000
G83.2 Monoplegia of upper limb	0.000	0.999	0.001
G83 Other paralytic syndromes	0.000	0.999	0.001
M99.50 Intervertebral disc stenosis of neural canal (Head region)	0.001	0.999	0.000
G04.8 Other encephalitis, myelitis and encephalomyelitis	0.000	0.999	0.001
Y85.0 Sequelae of motor-vehicle accident	0.000	0.999	0.001
I06.0 Rheumatic aortic stenosis	0.001	0.999	0.000
I25.0 Atherosclerotic cardiovascular disease, so described	0.001	0.999	0.000
K14.6 Glossodynia	0.001	0.999	0.000
M22.3 Other derangements of patella	0.001	0.999	0.000
M96.8 Other postprocedural musculoskeletal disorders	0.000	0.999	0.001
N99.2 Postprocedural adhesions of vagina	0.001	0.999	0.000
Z95.1 Presence of aortocoronary bypass graft	0.001	0.999	0.000
G50.9 Disorder of trigeminal nerve, unspecified	0.000	0.999	0.001
K29.4 Chronic atrophic gastritis	0.000	0.999	0.001
N99.0 Postprocedural renal failure	0.001	0.999	0.000
S86.9 Injury of unspecified muscle and tendon at lower leg level	0.001	0.999	0.000
T18.9 Foreign body in alimentary tract, part unspecified	0.001	0.999	0.000
T87.6 Other and unspecified complications of amputation stump	0.001	0.999	0.000
T17 Foreign body in respiratory tract	0.001	0.999	0.000
M25.55 Pain in joint (Pelvic region and thigh)	0.000	0.999	0.001
S02.51 Fracture of tooth (open)	0.000	0.999	0.001
C57.0 Fallopian tube	0.000	0.999	0.001
O04.1 Incomplete, complicated by delayed or excessive haemorrhage	0.001	0.999	0.000
O81.4 Vacuum extractor delivery	0.001	0.999	0.000
S42.4 Fracture of lower end of humerus	0.000	0.999	0.001
I06.1 Rheumatic aortic insufficiency	0.001	0.999	0.000
J84.9 Interstitial pulmonary disease, unspecified	0.000	0.999	0.001
J84.0 Alveolar and parietoalveolar conditions	0.000	0.999	0.001
S86.1 Injury of other muscle(s) and tendon(s) of posterior muscle group at lower leg level	0.001	0.999	0.000
L43 Lichen planus	0.001	0.999	0.000
T18 Foreign body in alimentary tract	0.001	0.999	0.000
M82.19 Osteoporosis in endocrine disorders (Site unspecified)	0.000	0.999	0.001
M82.18 Osteoporosis in endocrine disorders (Other)	0.000	0.999	0.001
M82.17 Osteoporosis in endocrine disorders (Ankle and foot)	0.000	0.999	0.001
M82.16 Osteoporosis in endocrine disorders (Lower leg)	0.000	0.999	0.001
M82.15 Osteoporosis in endocrine disorders (Pelvic region and thigh)	0.000	0.999	0.001
M82.14 Osteoporosis in endocrine disorders (Hand)	0.000	0.999	0.001
M82.13 Osteoporosis in endocrine disorders (Forearm)	0.000	0.999	0.001
M82.12 Osteoporosis in endocrine disorders (Upper arm)	0.000	0.999	0.001
K14.1 Geographic tongue	0.001	0.999	0.000
M25.91 Joint disorder, unspecified (Shoulder region)	0.000	0.999	0.001
G83.5 Locked-in syndrome	0.000	0.999	0.001
G83.3 Monoplegia, unspecified	0.000	0.999	0.001
G83.0 Diplegia of upper limbs	0.000	0.999	0.001
S93.3 Dislocation of other and unspecified parts of foot	0.000	0.999	0.001
T18.0 Foreign body in mouth	0.001	0.999	0.000
S86 Injury of muscle and tendon at lower leg level	0.001	0.999	0.000
M48.56 Collapsed vertebra, not elsewhere classified (Lumbar region)	0.000	0.999	0.001
M87.20 Osteonecrosis due to previous trauma (Multiple sites)	0.001	0.999	0.000
D63.8 Anaemia in other chronic diseases classified elsewhere	0.001	0.999	0.000
S86.3 Injury of muscle(s) and tendon(s) of peroneal muscle group at lower leg level	0.001	0.999	0.000
S72.80 Fractures of other parts of femur (closed)	0.001	0.999	0.000
F32.2 Severe depressive episode without psychotic symptoms	0.001	0.999	0.000
F81.9 Developmental disorder of scholastic skills, unspecified	0.000	0.999	0.001
L91.0 Keloid scar	0.000	0.999	0.001
T17.4 Foreign body in trachea	0.001	0.999	0.000
T17.1 Foreign body in nostril	0.001	0.999	0.000
T17.0 Foreign body in nasal sinus	0.001	0.999	0.000
N99 Postprocedural disorders of genito-urinary system, not elsewhere classified	0.001	0.999	0.000
M48.54 Collapsed vertebra, not elsewhere classified (Thoracic region)	0.000	0.999	0.001
C16.2 Body of stomach	0.001	0.999	0.000
G00.9 Bacterial meningitis, unspecified	0.000	0.999	0.001
L43.3 Subacute (active) lichen planus	0.001	0.999	0.000
L43.2 Lichenoid drug reaction	0.001	0.999	0.000
L43.1 Bullous lichen planus	0.001	0.999	0.000
L43.0 Hypertrophic lichen planus	0.001	0.999	0.000
N99.8 Other postprocedural disorders of genito-urinary system	0.001	0.999	0.000
K14 Diseases of tongue	0.001	0.999	0.000
D41.0 Kidney	0.001	0.999	0.000
J17.0 Pneumonia in bacterial diseases classified elsewhere	0.001	0.999	0.000
L56.8 Other specified acute skin changes due to ultraviolet radiation	0.001	0.999	0.000
T17.9 Foreign body in respiratory tract, part unspecified	0.001	0.999	0.000
T18.8 Foreign body in other and multiple parts of alimentary tract	0.001	0.999	0.000
T18.4 Foreign body in colon	0.001	0.999	0.000
T18.3 Foreign body in small intestine	0.001	0.999	0.000
K25.3 Acute without haemorrhage or perforation	0.000	0.999	0.001
R84.5 Abnormal microbiological findings	0.001	0.999	0.000
S86.0 Injury of Achilles tendon	0.001	0.999	0.000
S86.7 Injury of multiple muscles and tendons at lower leg level	0.001	0.999	0.000
I25 Chronic ischaemic heart disease	0.001	0.999	0.000
M66.34 Spontaneous rupture of flexor tendons (Hand)	0.001	0.999	0.000
S82.81 Fractures of other parts of lower leg (open)	0.001	0.999	0.000
K45.8 Other specified abdominal hernia without obstruction or gangrene	0.001	0.999	0.000
L43.8 Other lichen planus	0.001	0.999	0.000
N50.1 Vascular disorders of male genital organs	0.000	0.999	0.001
T17.8 Foreign body in other and multiple parts of respiratory tract	0.001	0.999	0.000
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes	0.001	0.999	0.000
E87.0 Hyperosmolality and hypernatraemia	0.000	0.999	0.001
K14.5 Plicated tongue	0.001	0.999	0.000
K14.4 Atrophy of tongue papillae	0.001	0.999	0.000
K14.3 Hypertrophy of tongue papillae	0.001	0.999	0.000
K14.2 Median rhomboid glossitis	0.001	0.999	0.000
T17.3 Foreign body in larynx	0.001	0.999	0.000
M62.88 Other specified disorders of muscle (Other)	0.001	0.999	0.000
G06.0 Intracranial abscess and granuloma	0.001	0.999	0.000
G11.1 Early-onset cerebellar ataxia	0.001	0.999	0.000
S31.7 Multiple open wounds of abdomen, lower back and pelvis	0.001	0.999	0.000
Y59.3 Immunoglobulin	0.001	0.999	0.000
I07 Rheumatic tricuspid valve diseases	0.001	0.999	0.000
S86.00 Unspecified injury of Achilles tendon	0.001	0.999	0.000
D86.1 Sarcoidosis of lymph nodes	0.001	0.999	0.000
I25.6 Silent myocardial ischaemia	0.001	0.999	0.000
J84.8 Other specified interstitial pulmonary diseases	0.000	0.999	0.001
K76.7 Hepatorenal syndrome	0.000	0.999	0.001
T17.5 Foreign body in bronchus	0.001	0.999	0.000
M25.99 Joint disorder, unspecified (Site unspecified)	0.000	0.999	0.001
I89.1 Lymphangitis	0.001	0.999	0.000
K25.7 Chronic without haemorrhage or perforation	0.000	0.999	0.001
T18.2 Foreign body in stomach	0.001	0.999	0.000
I05 Rheumatic mitral valve diseases	0.001	0.999	0.000
G11.9 Hereditary ataxia, unspecified	0.001	0.999	0.000
I05.2 Mitral stenosis with insufficiency	0.001	0.999	0.000
I07.9 Tricuspid valve disease, unspecified	0.001	0.999	0.000
I07.8 Other tricuspid valve diseases	0.001	0.999	0.000
I07.2 Tricuspid stenosis with insufficiency	0.001	0.999	0.000
I07.0 Tricuspid stenosis	0.001	0.999	0.000
K76.0 Fatty (change of) liver, not elsewhere classified	0.000	0.999	0.001
M25.9 Joint disorder, unspecified	0.000	0.999	0.001
O04.9 Complete or unspecified, without complication	0.001	0.999	0.000
S70.0 Contusion of hip	0.001	0.999	0.000
S72.1 Pertrochanteric fracture	0.001	0.999	0.000
S86.2 Injury of muscle(s) and tendon(s) of anterior muscle group at lower leg level	0.001	0.999	0.000
M62.84 Other specified disorders of muscle (Hand)	0.001	0.999	0.000
S12.10 Fracture of second cervical vertebra (closed)	0.001	0.999	0.000
F10.4 Withdrawal state with delirium	0.000	0.999	0.001
N99.1 Postprocedural urethral stricture	0.001	0.999	0.000
Q23.0 Congenital stenosis of aortic valve	0.000	0.999	0.001
W45.6 Industrial and construction area	0.001	0.999	0.000
M24.23 Disorder of ligament (Forearm)	0.000	0.999	0.001
M25.98 Joint disorder, unspecified (Other)	0.000	0.999	0.001
M25.92 Joint disorder, unspecified (Upper arm)	0.000	0.999	0.001
M25.90 Joint disorder, unspecified (Multiple sites)	0.000	0.999	0.001
S72.11 Pertrochanteric fracture (open)	0.001	0.999	0.000
D51.3 Other dietary vitamin B12 deficiency anaemia	0.001	0.999	0.000
G82.2 Paraplegia, unspecified	0.000	0.999	0.001
H54.9 Unspecified visual impairment (binocular)	0.000	0.999	0.001
I05.8 Other mitral valve diseases	0.001	0.999	0.000
L72.8 Other follicular cysts of skin and subcutaneous tissue	0.000	0.999	0.001
N99.9 Postprocedural disorder of genito-urinary system, unspecified	0.001	0.999	0.000
I70.10 Atherosclerosis of renal artery (without gangrene)	0.001	0.999	0.000
M62.87 Other specified disorders of muscle (Ankle and foot)	0.001	0.999	0.000
S42.41 Fracture of lower end of humerus (open)	0.000	0.999	0.001
G00.2 Streptococcal meningitis	0.000	0.999	0.001
G00.1 Pneumococcal meningitis	0.000	0.999	0.001
G04.9 Encephalitis, myelitis and encephalomyelitis, unspecified	0.000	0.999	0.001
H91.3 Deaf mutism, not elsewhere classified	0.001	0.999	0.000
K25.0 Acute with haemorrhage	0.000	0.999	0.001
L08.8 Other specified local infections of skin and subcutaneous tissue	0.000	0.999	0.001
Q25.1 Coarctation of aorta	0.000	0.999	0.001
W60.9 Unspecified place	0.001	0.999	0.000
Z29.0 Isolation	0.001	0.999	0.000
G04 Encephalitis, myelitis and encephalomyelitis	0.000	0.999	0.001
X78 Intentional self-harm by sharp object	0.001	0.999	0.000
M25.60 Stiffness of joint, not elsewhere classified (Multiple sites)	0.000	0.999	0.001
M25.95 Joint disorder, unspecified (Pelvic region and thigh)	0.000	0.999	0.001
M76.67 Achilles tendinitis (Ankle and foot)	0.001	0.999	0.000
M79.87 Other specified soft tissue disorders (Ankle and foot)	0.000	0.999	0.001
C57.9 Female genital organ, unspecified	0.000	0.999	0.001
C57.7 Other specified female genital organs	0.000	0.999	0.001
C57.4 Uterine adnexa, unspecified	0.000	0.999	0.001
C57.3 Parametrium	0.000	0.999	0.001
C57.2 Round ligament	0.000	0.999	0.001
C57.1 Broad ligament	0.000	0.999	0.001
D16.5 Lower jaw bone	0.000	0.999	0.001
G04.2 Bacterial meningoencephalitis and meningomyelitis, not elsewhere classified	0.000	0.999	0.001
G04.1 Tropical spastic paraplegia	0.000	0.999	0.001
G04.0 Acute disseminated encephalitis	0.000	0.999	0.001
G83.4 Cauda equina syndrome	0.000	0.999	0.001
H35.7 Separation of retinal layers	0.000	0.999	0.001
I67.1 Cerebral aneurysm, nonruptured	0.001	0.999	0.000
K62.8 Other specified diseases of anus and rectum	0.000	0.999	0.001
N42.0 Calculus of prostate	0.000	0.999	0.001
T19.1 Foreign body in bladder	0.001	0.999	0.000
W55.0 Home	0.001	0.999	0.000
X78.9 Unspecified place	0.001	0.999	0.000
X78.8 Other specified place	0.001	0.999	0.000
X78.7 Farm	0.001	0.999	0.000
X78.6 Industrial and construction area	0.001	0.999	0.000
X78.5 Trade and service area	0.001	0.999	0.000
X78.4 Street and highway	0.001	0.999	0.000
X78.3 Sports and athletics area	0.001	0.999	0.000
X78.2 School, other institution and public administrative area	0.001	0.999	0.000
X78.1 Residential institution	0.001	0.999	0.000
C57 Malignant neoplasm of other and unspecified female genital organs	0.000	0.999	0.001
Q23 Congenital malformations of aortic and mitral valves	0.000	0.999	0.001
M25.97 Joint disorder, unspecified (Ankle and foot)	0.000	0.999	0.001
M25.93 Joint disorder, unspecified (Forearm)	0.000	0.999	0.001
M62.89 Other specified disorders of muscle (Site unspecified)	0.001	0.999	0.000
M66.36 Spontaneous rupture of flexor tendons (Lower leg)	0.001	0.999	0.000
M66.31 Spontaneous rupture of flexor tendons (Shoulder region)	0.001	0.999	0.000
X78.99 Intentional self-harm by sharp object: Unspecified place: During unspecified activity	0.001	0.999	0.000
G00.8 Other bacterial meningitis	0.000	0.999	0.001
G00.3 Staphylococcal meningitis	0.000	0.999	0.001
G00.0 Haemophilus meningitis	0.000	0.999	0.001
G05.1 Encephalitis, myelitis and encephalomyelitis in viral diseases classified elsewhere	0.000	0.999	0.001
I61.5 Intracerebral haemorrhage, intraventricular	0.001	0.999	0.000
K76.5 Hepatic veno-occlusive disease	0.000	0.999	0.001
K76.4 Peliosis hepatis	0.000	0.999	0.001
K76.3 Infarction of liver	0.000	0.999	0.001
K76.2 Central haemorrhagic necrosis of liver	0.000	0.999	0.001
Q23.9 Congenital malformation of aortic and mitral valves, unspecified	0.000	0.999	0.001
Q23.8 Other congenital malformations of aortic and mitral valves	0.000	0.999	0.001
Q23.4 Hypoplastic left heart syndrome	0.000	0.999	0.001
Q23.2 Congenital mitral stenosis	0.000	0.999	0.001
S01.1 Open wound of eyelid and periocular area	0.000	0.999	0.001
S31.0 Open wound of lower back and pelvis	0.001	0.999	0.000
W64.9 Unspecified place	0.001	0.999	0.000
Y00.9 Unspecified place	0.001	0.999	0.000
G00 Bacterial meningitis, not elsewhere classified	0.000	0.999	0.001
K76 Other diseases of liver	0.000	0.999	0.001
M48.50 Collapsed vertebra, not elsewhere classified (Multiple sites in spine)	0.000	0.999	0.001
D17.5 Benign lipomatous neoplasm of intra-abdominal organs	0.001	0.999	0.000
E34.9 Endocrine disorder, unspecified	0.001	0.999	0.000
J35.9 Chronic disease of tonsils and adenoids, unspecified	0.001	0.999	0.000
L56.9 Acute skin change due to ultraviolet radiation, unspecified	0.001	0.999	0.000
M62.8 Other specified disorders of muscle	0.001	0.999	0.000
S31.5 Open wound of other and unspecified external genital organs	0.001	0.999	0.000
S31.3 Open wound of scrotum and testes	0.001	0.999	0.000
S31 Open wound of abdomen, lower back and pelvis	0.001	0.999	0.000
M00.97 Pyogenic arthritis, unspecified (Ankle and foot)	0.000	0.999	0.001
M00.92 Pyogenic arthritis, unspecified (Upper arm)	0.000	0.999	0.001
B00.2 Herpesviral gingivostomatitis and pharyngotonsillitis	0.001	0.999	0.000
C57.8 Overlapping lesion of female genital organs	0.000	0.999	0.001
G90.2 Horner's syndrome	0.001	0.999	0.000
H54.4 Blindness, one eye	0.000	0.999	0.001
I61.0 Intracerebral haemorrhage in hemisphere, subcortical	0.000	0.999	0.001
I89.9 Non-infective disorder of lymphatic vessels and lymph nodes, unspecified	0.001	0.999	0.000
S31.8 Open wound of other and unspecified parts of abdomen	0.001	0.999	0.000
S31.2 Open wound of penis	0.001	0.999	0.000
T15.9 Foreign body on external eye, unspecified	0.001	0.999	0.000
T15.1 Foreign body in conjunctival sac	0.001	0.999	0.000
T19.9 Foreign body in genito-urinary tract, part unspecified	0.001	0.999	0.000
T19.8 Foreign body in other and multiple parts of genito-urinary tract	0.001	0.999	0.000
T19.3 Foreign body in uterus [any part]	0.001	0.999	0.000
T19.0 Foreign body in urethra	0.001	0.999	0.000
H54 Blindness and low vision	0.000	0.999	0.001
T16 Foreign body in ear	0.001	0.999	0.000
T15-T19 Effects of foreign body entering through natural orifice	0.001	0.999	0.000
M25.33 Other instability of joint (Forearm)	0.001	0.999	0.000
M25.65 Stiffness of joint, not elsewhere classified (Pelvic region and thigh)	0.000	0.999	0.001
M25.63 Stiffness of joint, not elsewhere classified (Forearm)	0.000	0.999	0.001
M48.58 Collapsed vertebra, not elsewhere classified (Sacral and sacrococcygeal region)	0.000	0.999	0.001
M48.57 Collapsed vertebra, not elsewhere classified (Lumbosacral region)	0.000	0.999	0.001
M48.53 Collapsed vertebra, not elsewhere classified (Cervicothoracic region)	0.000	0.999	0.001
M48.52 Collapsed vertebra, not elsewhere classified (Cervical region)	0.000	0.999	0.001
M48.51 Collapsed vertebra, not elsewhere classified (Occipito-atlanto-axial region)	0.000	0.999	0.001
M85.88 Other specified disorders of bone density and structure (Other)	0.001	0.999	0.000
S12.90 Fracture of neck, part unspecified (closed)	0.001	0.999	0.000
S92.20 Fracture of other tarsal bone(s) (closed)	0.000	0.999	0.001
D51.2 Transcobalamin II deficiency	0.001	0.999	0.000
D51.1 Vitamin B12 deficiency anaemia due to selective vitamin B12 malabsorption with proteinuria	0.001	0.999	0.000
E27.1 Primary adrenocortical insufficiency	0.000	0.999	0.001
I25.4 Coronary artery aneurysm	0.001	0.999	0.000
L89.3 Stage IV decubitus ulcer	0.000	0.999	0.001
N99.3 Prolapse of vaginal vault after hysterectomy	0.001	0.999	0.000
Q60.0 Renal agenesis, unilateral	0.000	0.999	0.001
S00.9 Superficial injury of head, part unspecified	0.000	0.999	0.001
S02.1 Fracture of base of skull	0.000	0.999	0.001
T15.8 Foreign body in other and multiple parts of external eye	0.001	0.999	0.000
W55.7 Farm	0.001	0.999	0.000
I89 Other non-infective disorders of lymphatic vessels and lymph nodes	0.001	0.999	0.000
T19 Foreign body in genito-urinary tract	0.001	0.999	0.000
T15 Foreign body on external eye	0.001	0.999	0.000
M25.69 Stiffness of joint, not elsewhere classified (Site unspecified)	0.000	0.999	0.001
M85.45 Solitary bone cyst (Pelvic region and thigh)	0.001	0.999	0.000
M99.59 Intervertebral disc stenosis of neural canal-Abdomen/other	0.001	0.999	0.000
M99.58 Intervertebral disc stenosis of neural canal-Rib cage	0.001	0.999	0.000
M99.57 Intervertebral disc stenosis of neural canal-Upper extremit	0.001	0.999	0.000
M99.56 Intervertebral disc stenosis of neural canal-Lower extremit	0.001	0.999	0.000
M99.55 Intervertebral disc stenosis of neural canal (Pelvic region)	0.001	0.999	0.000
M99.54 Intervertebral disc stenosis of neural canal (Sacral region)	0.001	0.999	0.000
M99.52 Intervertebral disc stenosis of neural canal (Thoracic region)	0.001	0.999	0.000
M99.51 Intervertebral disc stenosis of neural canal (Cervical region)	0.001	0.999	0.000
S62.51 Fracture of thumb (open)	0.001	0.999	0.000
S72.01 Fracture of neck of femur (open)	0.001	0.999	0.000
T02.50 Fractures involving multiple regions of both lower limbs (closed)	0.000	0.999	0.001
D33.3 Cranial nerves	0.001	0.999	0.000
G11.8 Other hereditary ataxias	0.001	0.999	0.000
G11.3 Cerebellar ataxia with defective DNA repair	0.001	0.999	0.000
G11.2 Late-onset cerebellar ataxia	0.001	0.999	0.000
G11.0 Congenital nonprogressive ataxia	0.001	0.999	0.000
H54.6 Unqualified visual loss, one eye	0.000	0.999	0.001
J99.1 Respiratory disorders in other diffuse connective tissue disorders	0.000	0.999	0.001
K76.1 Chronic passive congestion of liver	0.000	0.999	0.001
M48.5 Collapsed vertebra, not elsewhere classified	0.000	0.999	0.001
S69.9 Unspecified injury of wrist and hand	0.000	0.999	0.001
S93.0 Dislocation of ankle joint	0.000	0.999	0.001
T18.5 Foreign body in anus and rectum	0.001	0.999	0.000
D51 Vitamin B12 deficiency anaemia	0.001	0.999	0.000
M66.39 Spontaneous rupture of flexor tendons (Site unspecified)	0.001	0.999	0.000
M66.38 Spontaneous rupture of flexor tendons (Other)	0.001	0.999	0.000
M66.37 Spontaneous rupture of flexor tendons (Ankle and foot)	0.001	0.999	0.000
M66.35 Spontaneous rupture of flexor tendons (Pelvic region and thigh)	0.001	0.999	0.000
M66.33 Spontaneous rupture of flexor tendons (Forearm)	0.001	0.999	0.000
M66.32 Spontaneous rupture of flexor tendons (Upper arm)	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations