TreeWAS – Variant ID: rs477992

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
H93.1 Tinnitus	0.181	0.819	0.000
H90.3 Sensorineural hearing loss, bilateral	0.179	0.821	0.000
H93 Other disorders of ear, not elsewhere classified	0.177	0.823	0.000
H90-H95 Other disorders of ear	0.177	0.823	0.000
H90 Conductive and sensorineural hearing loss	0.175	0.825	0.000
H92 Otalgia and effusion of ear	0.161	0.839	0.000
H90.2 Conductive hearing loss, unspecified	0.159	0.841	0.000
H90.1 Conductive hearing loss, unilateral with unrestricted hearing on the contralateral side	0.155	0.845	0.000
Chapter VIII Diseases of the ear and mastoid process	0.142	0.858	0.000
H60-H62 Diseases of external ear	0.140	0.860	0.000
H92.2 Otorrhagia	0.140	0.860	0.000
H93.9 Disorder of ear, unspecified	0.139	0.860	0.000
H92.0 Otalgia	0.133	0.867	0.000
H60 Otitis externa	0.133	0.867	0.000
H61 Other disorders of external ear	0.129	0.871	0.000
H93.0 Degenerative and vascular disorders of ear	0.127	0.873	0.000
H94 Other disorders of ear in diseases classified elsewhere	0.127	0.873	0.000
H60.9 Otitis externa, unspecified	0.127	0.873	0.000
H93.8 Other specified disorders of ear	0.126	0.874	0.000
H90.5 Sensorineural hearing loss, unspecified	0.124	0.875	0.000
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified	0.122	0.878	0.000
H93.2 Other abnormal auditory perceptions	0.121	0.879	0.000
H60.3 Other infective otitis externa	0.120	0.880	0.000
H92.1 Otorrhoea	0.119	0.881	0.000
H90.7 Mixed conductive and sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side	0.117	0.883	0.000
H61.1 Non-infective disorders of pinna	0.117	0.883	0.000
H61.2 Impacted cerumen	0.116	0.884	0.000
H90.6 Mixed conductive and sensorineural hearing loss, bilateral	0.116	0.884	0.000
H93.3 Disorders of acoustic nerve	0.113	0.887	0.000
H61.3 Acquired stenosis of external ear canal	0.112	0.888	0.000
H62 Disorders of external ear in diseases classified elsewhere	0.101	0.899	0.000
H60.8 Other otitis externa	0.097	0.903	0.000
H60.2 Malignant otitis externa	0.097	0.903	0.000
H65-H75 Diseases of middle ear and mastoid	0.095	0.905	0.000
H61.8 Other specified disorders of external ear	0.092	0.908	0.000
H60.1 Cellulitis of external ear	0.092	0.908	0.000
H60.4 Cholesteatoma of external ear	0.091	0.908	0.000
H90.0 Conductive hearing loss, bilateral	0.091	0.909	0.000
H94.8 Other specified disorders of ear in diseases classified elsewhere	0.091	0.909	0.000
H94.0 Acoustic neuritis in infectious and parasitic diseases classified elsewhere	0.091	0.909	0.000
H95.9 Postprocedural disorder of ear and mastoid process, unspecified	0.090	0.910	0.000
H60.0 Abscess of external ear	0.090	0.910	0.000
H95.8 Other postprocedural disorders of ear and mastoid process	0.086	0.914	0.000
H95.1 Other disorders following mastoidectomy	0.084	0.915	0.000
H66 Suppurative and unspecified otitis media	0.084	0.916	0.000
H95.0 Recurrent cholesteatoma of postmastoidectomy cavity	0.083	0.917	0.000
H90.4 Sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side	0.080	0.920	0.000
H69 Other disorders of Eustachian tube	0.080	0.920	0.000
K51.2 Ulcerative (chronic) proctitis	0.000	0.921	0.079
K51 Ulcerative colitis	0.000	0.924	0.076
H70 Mastoiditis and related conditions	0.076	0.924	0.000
H68 Eustachian salpingitis and obstruction	0.075	0.924	0.000
K51.0 Ulcerative (chronic) enterocolitis	0.000	0.926	0.074
H66.1 Chronic tubotympanic suppurative otitis media	0.073	0.927	0.000
H62.8 Other disorders of external ear in diseases classified elsewhere	0.072	0.928	0.000
H62.4 Otitis externa in other diseases classified elsewhere	0.072	0.928	0.000
H62.3 Otitis externa in other infectious and parasitic diseases classified elsewhere	0.072	0.928	0.000
H62.2 Otitis externa in mycoses	0.072	0.928	0.000
H62.1 Otitis externa in viral diseases classified elsewhere	0.072	0.928	0.000
H62.0 Otitis externa in bacterial diseases classified elsewhere	0.072	0.928	0.000
H69.9 Eustachian tube disorder, unspecified	0.072	0.928	0.000
H66.4 Suppurative otitis media, unspecified	0.071	0.929	0.000
H80-H83 Diseases of inner ear	0.071	0.929	0.000
K51.4 Pseudopolyposis of colon	0.000	0.930	0.070
H71 Cholesteatoma of middle ear	0.069	0.931	0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere	0.068	0.932	0.000
H67 Otitis media in diseases classified elsewhere	0.068	0.932	0.000
H60.5 Acute otitis externa, non-infective	0.064	0.936	0.000
K51.9 Ulcerative colitis, unspecified	0.000	0.936	0.064
K51.3 Ulcerative (chronic) rectosigmoiditis	0.000	0.936	0.064
H72 Perforation of tympanic membrane	0.062	0.938	0.000
H68.1 Obstruction of Eustachian tube	0.062	0.938	0.000
H70.1 Chronic mastoiditis	0.061	0.938	0.000
H61.9 Disorder of external ear, unspecified	0.061	0.939	0.000
H66.2 Chronic atticoantral suppurative otitis media	0.061	0.939	0.000
H66.9 Otitis media, unspecified	0.061	0.939	0.000
H90.8 Mixed conductive and sensorineural hearing loss, unspecified	0.060	0.939	0.001
H66.0 Acute suppurative otitis media	0.060	0.940	0.000
H70.0 Acute mastoiditis	0.058	0.942	0.000
H69.0 Patulous Eustachian tube	0.057	0.943	0.000
H70.9 Mastoiditis, unspecified	0.057	0.943	0.000
K51.5 Mucosal proctocolitis	0.000	0.944	0.056
H70.2 Petrositis	0.055	0.945	0.000
H66.3 Other chronic suppurative otitis media	0.055	0.945	0.000
H68.0 Eustachian salpingitis	0.054	0.946	0.000
H80 Otosclerosis	0.053	0.947	0.000
H61.0 Perichondritis of external ear	0.053	0.947	0.000
H72.8 Other perforations of tympanic membrane	0.053	0.947	0.000
H82 Vertiginous syndromes in diseases classified elsewhere	0.051	0.949	0.000
H70.8 Other mastoiditis and related conditions	0.050	0.949	0.000
H73 Other disorders of tympanic membrane	0.050	0.950	0.000
H69.8 Other specified disorders of Eustachian tube	0.050	0.950	0.000
K51.1 Ulcerative (chronic) ileocolitis	0.000	0.950	0.050
H72.2 Other marginal perforations of tympanic membrane	0.049	0.951	0.000
H67.8 Otitis media in other diseases classified elsewhere	0.049	0.951	0.000
H67.1 Otitis media in viral diseases classified elsewhere	0.049	0.951	0.000
H67.0 Otitis media in bacterial diseases classified elsewhere	0.049	0.951	0.000
H75.8 Other specified disorders of middle ear and mastoid in diseases classified elsewhere	0.049	0.951	0.000
H75.0 Mastoiditis in infectious and parasitic diseases classified elsewhere	0.049	0.951	0.000
H72.1 Attic perforation of tympanic membrane	0.047	0.953	0.000
H80.0 Otosclerosis involving oval window, nonobliterative	0.042	0.958	0.000
K51.8 Other ulcerative colitis	0.000	0.960	0.040
H91 Other hearing loss	0.039	0.961	0.000
H65 Nonsuppurative otitis media	0.039	0.961	0.000
H80.9 Otosclerosis, unspecified	0.039	0.961	0.000
H80.2 Cochlear otosclerosis	0.038	0.961	0.000
H80.1 Otosclerosis involving oval window, obliterative	0.038	0.961	0.000
H83 Other diseases of inner ear	0.038	0.962	0.000
H81 Disorders of vestibular function	0.037	0.963	0.000
H73.8 Other specified disorders of tympanic membrane	0.037	0.963	0.000
H80.8 Other otosclerosis	0.036	0.964	0.000
H72.9 Perforation of tympanic membrane, unspecified	0.034	0.966	0.000
H73.0 Acute myringitis	0.033	0.967	0.000
H73.1 Chronic myringitis	0.031	0.969	0.000
H73.9 Disorder of tympanic membrane, unspecified	0.030	0.969	0.000
H83.8 Other specified diseases of inner ear	0.031	0.969	0.000
H65.0 Acute serous otitis media	0.030	0.970	0.000
H91.0 Ototoxic hearing loss	0.030	0.970	0.000
H91.3 Deaf mutism, not elsewhere classified	0.029	0.971	0.000
H65.1 Other acute nonsuppurative otitis media	0.029	0.971	0.000
H65.2 Chronic serous otitis media	0.029	0.971	0.000
H81.0 Meniere's disease	0.029	0.971	0.000
H83.2 Labyrinthine dysfunction	0.028	0.972	0.000
K05.3 Chronic periodontitis	0.000	0.972	0.028
H81.4 Vertigo of central origin	0.028	0.972	0.000
H83.1 Labyrinthine fistula	0.027	0.972	0.000
H91.2 Sudden idiopathic hearing loss	0.027	0.972	0.000
H74 Other disorders of middle ear and mastoid	0.027	0.973	0.000
H65.4 Other chronic nonsuppurative otitis media	0.027	0.973	0.000
H83.3 Noise effects on inner ear	0.025	0.974	0.000
H81.8 Other disorders of vestibular function	0.025	0.974	0.000
H81.3 Other peripheral vertigo	0.025	0.974	0.000
H83.9 Disease of inner ear, unspecified	0.025	0.975	0.000
H81.1 Benign paroxysmal vertigo	0.025	0.975	0.000
K05 Gingivitis and periodontal diseases	0.000	0.977	0.023
K05.6 Periodontal disease, unspecified	0.000	0.978	0.022
H72.0 Central perforation of tympanic membrane	0.021	0.979	0.000
H81.9 Disorder of vestibular function, unspecified	0.021	0.979	0.000
H74.1 Adhesive middle ear disease	0.021	0.979	0.000
H74.9 Disorder of middle ear and mastoid, unspecified	0.021	0.979	0.000
H81.2 Vestibular neuronitis	0.020	0.980	0.000
H91.8 Other specified hearing loss	0.019	0.981	0.000
K05.0 Acute gingivitis	0.000	0.981	0.019
H65.3 Chronic mucoid otitis media	0.019	0.981	0.000
G95.2 Cord compression, unspecified	0.018	0.982	0.000
K05.4 Periodontosis	0.000	0.983	0.017
H91.1 Presbycusis	0.017	0.983	0.001
I89.0 Lymphoedema, not elsewhere classified	0.017	0.983	0.000
K05.5 Other periodontal diseases	0.000	0.983	0.017
K05.2 Acute periodontitis	0.000	0.983	0.017
G95 Other diseases of spinal cord	0.017	0.983	0.000
K05.1 Chronic gingivitis	0.000	0.983	0.016
H74.2 Discontinuity and dislocation of ear ossicles	0.016	0.984	0.000
H74.0 Tympanosclerosis	0.016	0.984	0.000
H74.4 Polyp of middle ear	0.016	0.984	0.000
H74.3 Other acquired abnormalities of ear ossicles	0.015	0.985	0.000
G95.1 Vascular myelopathies	0.015	0.985	0.000
G95.9 Disease of spinal cord, unspecified	0.014	0.986	0.000
H83.0 Labyrinthitis	0.014	0.986	0.000
G95.0 Syringomyelia and syringobulbia	0.014	0.986	0.000
H74.8 Other specified disorders of middle ear and mastoid	0.013	0.986	0.000
G95.8 Other specified diseases of spinal cord	0.012	0.987	0.000
K05.22 Aggressive periodontitis, generalized	0.000	0.988	0.012
G93.8 Other specified disorders of brain	0.011	0.989	0.000
J69.0 Pneumonitis due to food and vomit	0.011	0.989	0.000
H65.9 Nonsuppurative otitis media, unspecified	0.009	0.990	0.000
G93 Other disorders of brain	0.008	0.992	0.000
G90-G99 Other disorders of the nervous system	0.007	0.993	0.000
G94 Other disorders of brain in diseases classified elsewhere	0.007	0.993	0.000
G93.4 Encephalopathy, unspecified	0.007	0.993	0.000
G94.2 Hydrocephalus in other diseases classified elsewhere	0.007	0.993	0.000
I89 Other non-infective disorders of lymphatic vessels and lymph nodes	0.007	0.993	0.000
G93.6 Cerebral oedema	0.006	0.994	0.000
G93.1 Anoxic brain damage, not elsewhere classified	0.006	0.994	0.000
G93.7 Reye's syndrome	0.006	0.994	0.000
G51.0 Bell's palsy	0.006	0.994	0.000
G93.2 Benign intracranial hypertension	0.006	0.994	0.000
G94.1 Hydrocephalus in neoplastic disease	0.006	0.994	0.000
F81.9 Developmental disorder of scholastic skills, unspecified	0.006	0.994	0.000
G91 Hydrocephalus	0.006	0.994	0.000
G93.0 Cerebral cysts	0.005	0.994	0.000
G93.9 Disorder of brain, unspecified	0.005	0.995	0.000
J30.1 Allergic rhinitis due to pollen	0.005	0.995	0.000
H91.9 Hearing loss, unspecified	0.005	0.995	0.000
G92 Toxic encephalopathy	0.005	0.995	0.000
G90 Disorders of autonomic nervous system	0.005	0.995	0.000
G94.8 Other specified disorders of brain in diseases classified elsewhere	0.005	0.995	0.000
G94.0 Hydrocephalus in infectious and parasitic diseases classified elsewhere	0.005	0.995	0.000
I89.9 Non-infective disorder of lymphatic vessels and lymph nodes, unspecified	0.005	0.995	0.000
I89.1 Lymphangitis	0.005	0.995	0.000
J69 Pneumonitis due to solids and liquids	0.005	0.995	0.000
K50-K52 Noninfective enteritis and colitis	0.000	0.995	0.005
G98 Other disorders of nervous system, not elsewhere classified	0.005	0.995	0.000
Z86.3 Personal history of endocrine, nutritional and metabolic diseases	0.005	0.995	0.000
G91.8 Other hydrocephalus	0.005	0.995	0.000
G90.3 Multisystem degeneration	0.005	0.995	0.000
K02.9 Dental caries, unspecified	0.000	0.995	0.005
R29.8 Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems	0.005	0.995	0.000
I84.7 Unspecified thrombosed haemorrhoids	0.000	0.995	0.005
D86.9 Sarcoidosis, unspecified	0.004	0.996	0.000
G91.9 Hydrocephalus, unspecified	0.004	0.996	0.000
C25.1 Body of pancreas	0.004	0.996	0.000
D86 Sarcoidosis	0.004	0.996	0.000
G96 Other disorders of central nervous system	0.004	0.996	0.000
G91.2 Normal-pressure hydrocephalus	0.004	0.996	0.000
G93.5 Compression of brain	0.004	0.996	0.000
M45.X9 Ankylosing spondylitis (Site unspecified)	0.000	0.996	0.004
T40.2 Other opioids	0.004	0.996	0.000
D86.0 Sarcoidosis of lung	0.004	0.996	0.000
C25 Malignant neoplasm of pancreas	0.004	0.996	0.000
D86.8 Sarcoidosis of other and combined sites	0.004	0.996	0.000
G90.0 Idiopathic peripheral autonomic neuropathy	0.004	0.996	0.000
G90.4 Autonomic dysreflexia	0.004	0.996	0.000
G90.1 Familial dysautonomia [Riley-Day]	0.004	0.996	0.000
G91.3 Posttraumatic hydrocephalus, unspecified	0.004	0.996	0.000
I89.8 Other specified non-infective disorders of lymphatic vessels and lymph nodes	0.004	0.996	0.000
G90.9 Disorder of autonomic nervous system, unspecified	0.004	0.996	0.000
C25.9 Pancreas, unspecified	0.004	0.996	0.000
M45.X0 Ankylosing spondylitis (Multiple sites in spine)	0.000	0.996	0.004
M45.X2 Ankylosing spondylitis (Cervical region)	0.000	0.996	0.004
I80.1 Phlebitis and thrombophlebitis of femoral vein	0.004	0.996	0.000
Y56.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.000	0.996	0.004
D86.3 Sarcoidosis of skin	0.004	0.996	0.000
M45 Ankylosing spondylitis	0.000	0.996	0.004
F81 Specific developmental disorders of scholastic skills	0.004	0.996	0.000
G91.1 Obstructive hydrocephalus	0.004	0.996	0.000
J69.8 Pneumonitis due to other solids and liquids	0.004	0.996	0.000
J69.1 Pneumonitis due to oils and essences	0.004	0.996	0.000
R90.0 Intracranial space-occupying lesion	0.000	0.996	0.004
C25.4 Endocrine pancreas	0.004	0.996	0.000
Y79.2 Prosthetic and other implants, materials and accessory devices	0.004	0.996	0.000
C22.0 Liver cell carcinoma	0.004	0.996	0.000
C25.7 Other parts of pancreas	0.004	0.996	0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified	0.003	0.996	0.000
G96.0 Cerebrospinal fluid leak	0.003	0.996	0.000
C25.8 Overlapping lesion of pancreas	0.003	0.996	0.000
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes	0.003	0.996	0.000
G90.2 Horner's syndrome	0.003	0.996	0.000
G90.8 Other disorders of autonomic nervous system	0.003	0.996	0.000
C25.2 Tail of pancreas	0.003	0.996	0.000
G91.0 Communicating hydrocephalus	0.003	0.996	0.000
G96.9 Disorder of central nervous system, unspecified	0.003	0.997	0.000
C25.0 Head of pancreas	0.003	0.997	0.000
O16 Unspecified maternal hypertension	0.000	0.997	0.003
C25.3 Pancreatic duct	0.003	0.997	0.000
D21.1 Connective and other soft tissue of upper limb, including shoulder	0.003	0.997	0.000
D86.1 Sarcoidosis of lymph nodes	0.003	0.997	0.000
Z03.9 Observation for suspected disease or condition, unspecified	0.003	0.997	0.000
J94.8 Other specified pleural conditions	0.000	0.997	0.003
R16.1 Splenomegaly, not elsewhere classified	0.000	0.997	0.003
H11.3 Conjunctival haemorrhage	0.003	0.997	0.000
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)	0.000	0.997	0.003
M45.X7 Ankylosing spondylitis (Lumbosacral region)	0.000	0.997	0.003
M45.X5 Ankylosing spondylitis (Thoracolumbar region)	0.000	0.997	0.003
M45.X4 Ankylosing spondylitis (Thoracic region)	0.000	0.997	0.003
M45.X3 Ankylosing spondylitis (Cervicothoracic region)	0.000	0.997	0.003
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)	0.000	0.997	0.003
F81.8 Other developmental disorders of scholastic skills	0.003	0.997	0.000
F81.3 Mixed disorder of scholastic skills	0.003	0.997	0.000
F81.2 Specific disorder of arithmetical skills	0.003	0.997	0.000
F81.1 Specific spelling disorder	0.003	0.997	0.000
F81.0 Specific reading disorder	0.003	0.997	0.000
G96.8 Other specified disorders of central nervous system	0.003	0.997	0.000
M45.X6 Ankylosing spondylitis (Lumbar region)	0.000	0.997	0.003
M47.89 Other spondylosis (Site unspecified)	0.000	0.997	0.003
G97.9 Postprocedural disorder of nervous system, unspecified	0.003	0.997	0.000
G97.2 Intracranial hypotension following ventricular shunting	0.003	0.997	0.000
M86.97 Osteomyelitis, unspecified (Ankle and foot)	0.003	0.997	0.000
F84 Pervasive developmental disorders	0.003	0.997	0.000
D35.1 Parathyroid gland	0.000	0.997	0.003
F84.5 Asperger's syndrome	0.003	0.997	0.000
G93.3 Postviral fatigue syndrome	0.003	0.997	0.000
G97.8 Other postprocedural disorders of nervous system	0.002	0.997	0.000
F80-F89 Disorders of psychological development	0.003	0.997	0.000
F84.0 Childhood autism	0.003	0.997	0.000
Y79 Orthopaedic devices associated with adverse incidents	0.003	0.997	0.000
E21.3 Hyperparathyroidism, unspecified	0.000	0.997	0.003
T92.2 Sequelae of fracture at wrist and hand level	0.002	0.998	0.000
G97.1 Other reaction to spinal and lumbar puncture	0.002	0.998	0.000
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)	0.002	0.998	0.000
Y79.3 Surgical instruments, materials and devices (including sutures)	0.002	0.998	0.000
G96.1 Disorders of meninges, not elsewhere classified	0.002	0.998	0.000
Z40.0 Prophylactic surgery for risk-factors related to malignant neoplasms	0.002	0.998	0.000
S39.9 Unspecified injury of abdomen, lower back and pelvis	0.002	0.998	0.000
H25.9 Senile cataract, unspecified	0.000	0.998	0.002
F84.9 Pervasive developmental disorder, unspecified	0.002	0.998	0.000
F84.8 Other pervasive developmental disorders	0.002	0.998	0.000
F84.4 Overactive disorder associated with mental retardation and stereotyped movements	0.002	0.998	0.000
F84.3 Other childhood disintegrative disorder	0.002	0.998	0.000
F84.2 Rett's syndrome	0.002	0.998	0.000
F84.1 Atypical autism	0.002	0.998	0.000
L50.9 Urticaria, unspecified	0.000	0.998	0.002
B16.9 Acute hepatitis B without delta-agent and without hepatic coma	0.002	0.998	0.000
Q87.4 Marfan's syndrome	0.000	0.998	0.002
B37.8 Candidiasis of other sites	0.002	0.998	0.000
G51 Facial nerve disorders	0.002	0.998	0.000
H59.8 Other postprocedural disorders of eye and adnexa	0.002	0.998	0.000
J05.1 Acute epiglottitis	0.000	0.998	0.002
G51.8 Other disorders of facial nerve	0.002	0.998	0.000
Z80.5 Family history of malignant neoplasm of urinary tract	0.000	0.998	0.002
F89 Unspecified disorder of psychological development	0.002	0.998	0.000
F88 Other disorders of psychological development	0.002	0.998	0.000
F83 Mixed specific developmental disorders	0.002	0.998	0.000
F82 Specific developmental disorder of motor function	0.002	0.998	0.000
Y79.8 Miscellaneous devices, not elsewhere classified	0.002	0.998	0.000
Y79.1 Therapeutic (nonsurgical) and rehabilitative devices	0.002	0.998	0.000
Y79.0 Diagnostic and monitoring devices	0.002	0.998	0.000
J35.8 Other chronic diseases of tonsils and adenoids	0.002	0.998	0.000
M86.9 Osteomyelitis, unspecified	0.002	0.998	0.000
G97.0 Cerebrospinal fluid leak from spinal puncture	0.001	0.998	0.001
F80 Specific developmental disorders of speech and language	0.002	0.998	0.000
M86.67 Other chronic osteomyelitis (Ankle and foot)	0.002	0.998	0.000
M86.94 Osteomyelitis, unspecified (Hand)	0.002	0.998	0.000
J38.7 Other diseases of larynx	0.002	0.998	0.000
M21.17 Varus deformity, not elsewhere classified (Ankle and foot)	0.000	0.998	0.002
K14.0 Glossitis	0.002	0.998	0.000
G99 Other disorders of nervous system in diseases classified elsewhere	0.002	0.998	0.000
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)	0.002	0.998	0.000
M05.9 Seropositive rheumatoid arthritis, unspecified	0.002	0.998	0.000
M22.8 Other disorders of patella	0.000	0.998	0.002
K63.2 Fistula of intestine	0.000	0.998	0.002
M86.6 Other chronic osteomyelitis	0.002	0.998	0.000
J94 Other pleural conditions	0.000	0.998	0.002
K14.8 Other diseases of tongue	0.002	0.998	0.000
F80.1 Expressive language disorder	0.002	0.998	0.000
H11.8 Other specified disorders of conjunctiva	0.002	0.998	0.000
I50.0 Congestive heart failure	0.000	0.998	0.002
J94.2 Haemothorax	0.000	0.998	0.002
Q43.8 Other specified congenital malformations of intestine	0.002	0.998	0.000
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.002	0.998	0.000
G51.4 Facial myokymia	0.002	0.998	0.000
G51.2 Melkersson's syndrome	0.002	0.998	0.000
G51.1 Geniculate ganglionitis	0.002	0.998	0.000
Q43.9 Congenital malformation of intestine, unspecified	0.002	0.998	0.000
Q43.0 Meckel's diverticulum	0.002	0.998	0.000
U80.0 Penicillin resistant agent	0.000	0.998	0.002
H11.4 Other conjunctival vascular disorders and cysts	0.002	0.998	0.000
H11 Other disorders of conjunctiva	0.002	0.998	0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.002	0.998	0.000
H11.0 Pterygium	0.002	0.998	0.000
R72 Abnormality of white blood cells, not elsewhere classified	0.002	0.998	0.000
M86.93 Osteomyelitis, unspecified (Forearm)	0.002	0.998	0.000
M86.92 Osteomyelitis, unspecified (Upper arm)	0.002	0.998	0.000
M86.91 Osteomyelitis, unspecified (Shoulder region)	0.002	0.998	0.000
M86.90 Osteomyelitis, unspecified (Multiple sites)	0.002	0.998	0.000
C22.9 Liver, unspecified	0.002	0.998	0.000
F80.9 Developmental disorder of speech and language, unspecified	0.002	0.998	0.000
F80.8 Other developmental disorders of speech and language	0.002	0.998	0.000
F80.3 Acquired aphasia with epilepsy [Landau-Kleffner]	0.002	0.998	0.000
F80.0 Specific speech articulation disorder	0.002	0.998	0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts	0.002	0.998	0.000
Q38.7 Pharyngeal pouch	0.002	0.998	0.000
T40.5 Cocaine	0.002	0.998	0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs	0.000	0.998	0.002
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)	0.002	0.998	0.000
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)	0.002	0.998	0.000
C71.3 Parietal lobe	0.000	0.998	0.002
M86.99 Osteomyelitis, unspecified (Site unspecified)	0.002	0.998	0.000
O69.2 Labour and delivery complicated by other cord entanglement	0.002	0.998	0.000
Q43 Other congenital malformations of intestine	0.002	0.998	0.000
M86.95 Osteomyelitis, unspecified (Pelvic region and thigh)	0.002	0.998	0.000
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)	0.002	0.998	0.000
G99.8 Other specified disorders of nervous system in diseases classified elsewhere	0.001	0.998	0.000
G99.1 Other disorders of autonomic nervous system in other diseases classified elsewhere	0.001	0.998	0.000
O64.1 Obstructed labour due to breech presentation	0.002	0.998	0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.000	0.998	0.002
M86 Osteomyelitis	0.002	0.998	0.000
M86.68 Other chronic osteomyelitis (Other)	0.002	0.998	0.000
M86.66 Other chronic osteomyelitis (Lower leg)	0.002	0.998	0.000
C71.9 Brain, unspecified	0.000	0.998	0.002
J94.9 Pleural condition, unspecified	0.000	0.998	0.002
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)	0.002	0.998	0.000
H11.2 Conjunctival scars	0.002	0.998	0.000
M86.98 Osteomyelitis, unspecified (Other)	0.002	0.998	0.000
M90.75 Fracture of bone in neoplastic disease (Pelvic region and thigh)	0.002	0.998	0.000
O75.7 Vaginal delivery following previous Caesarean section	0.002	0.998	0.000
K14 Diseases of tongue	0.002	0.998	0.000
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)	0.002	0.998	0.000
M84.48 Pathological fracture, not elsewhere classified (Other)	0.002	0.998	0.000
K14.6 Glossodynia	0.002	0.998	0.000
N31.2 Flaccid neuropathic bladder, not elsewhere classified	0.000	0.998	0.002
M86.64 Other chronic osteomyelitis (Hand)	0.001	0.998	0.000
M86.63 Other chronic osteomyelitis (Forearm)	0.001	0.998	0.000
M86.62 Other chronic osteomyelitis (Upper arm)	0.001	0.998	0.000
M86.61 Other chronic osteomyelitis (Shoulder region)	0.001	0.998	0.000
M86.60 Other chronic osteomyelitis (Multiple sites)	0.001	0.998	0.000
J94.0 Chylous effusion	0.000	0.998	0.002
M86.4 Chronic osteomyelitis with draining sinus	0.002	0.998	0.000
M86.69 Other chronic osteomyelitis (Site unspecified)	0.001	0.998	0.000
S72.20 Subtrochanteric fracture (closed)	0.002	0.998	0.000
F80.2 Receptive language disorder	0.001	0.998	0.000
Y56.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.000	0.998	0.002
E21.0 Primary hyperparathyroidism	0.000	0.998	0.002
E78.9 Disorder of lipoprotein metabolism, unspecified	0.002	0.998	0.000
T40.1 Heroin	0.001	0.998	0.000
S52.40 Fracture of shafts of both ulna and radius (closed)	0.000	0.998	0.002
E21.2 Other hyperparathyroidism	0.000	0.998	0.002
G51.9 Disorder of facial nerve, unspecified	0.001	0.998	0.000
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.001	0.998	0.000
T40.8 Lysergide [LSD]	0.001	0.998	0.000
T40.7 Cannabis (derivatives)	0.001	0.998	0.000
T40.0 Opium	0.001	0.998	0.000
M86.46 Chronic osteomyelitis with draining sinus (Lower leg)	0.001	0.998	0.000
E21.5 Disorder of parathyroid gland, unspecified	0.000	0.998	0.002
T40.4 Other synthetic narcotics	0.002	0.998	0.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)	0.002	0.998	0.000
M86.65 Other chronic osteomyelitis (Pelvic region and thigh)	0.001	0.998	0.000
C22.7 Other specified carcinomas of liver	0.001	0.998	0.000
C22.4 Other sarcomas of liver	0.001	0.998	0.000
C22.3 Angiosarcoma of liver	0.001	0.998	0.000
C22.2 Hepatoblastoma	0.001	0.998	0.000
L73.2 Hidradenitis suppurativa	0.000	0.998	0.002
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)	0.001	0.998	0.000
I50.1 Left ventricular failure	0.000	0.998	0.002
T40.3 Methadone	0.001	0.998	0.000
Y56.9 Topical agent, unspecified	0.000	0.998	0.001
Y56.8 Other topical agents	0.000	0.998	0.001
Y56.7 Dental drugs, topically applied	0.000	0.998	0.001
Y56.6 Otorhinolaryngological drugs and preparations	0.000	0.998	0.001
Y56.5 Ophthalmological drugs and preparations	0.000	0.998	0.001
Y56.2 Local astringents and local detergents	0.000	0.998	0.001
Y56.1 Antipruritics	0.000	0.998	0.001
Q43.7 Persistent cloaca	0.001	0.998	0.000
Q43.6 Congenital fistula of rectum and anus	0.001	0.998	0.000
Q43.5 Ectopic anus	0.001	0.998	0.000
Q43.4 Duplication of intestine	0.001	0.998	0.000
Q43.2 Other congenital functional disorders of colon	0.001	0.998	0.000
R23.3 Spontaneous ecchymoses	0.000	0.998	0.002
B16 Acute hepatitis B	0.001	0.998	0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified	0.000	0.998	0.001
M86.5 Other chronic haematogenous osteomyelitis	0.001	0.998	0.000
M86.3 Chronic multifocal osteomyelitis	0.001	0.998	0.000
M86.2 Subacute osteomyelitis	0.001	0.998	0.000
M86.0 Acute haematogenous osteomyelitis	0.001	0.998	0.000
M86.96 Osteomyelitis, unspecified (Lower leg)	0.001	0.998	0.000
Q21.1 Atrial septal defect	0.002	0.998	0.000
Y56.3 Emollients, demulcents and protectants	0.000	0.998	0.001
J94.1 Fibrothorax	0.000	0.999	0.001
K14.9 Disease of tongue, unspecified	0.001	0.999	0.000
K14.5 Plicated tongue	0.001	0.999	0.000
K14.4 Atrophy of tongue papillae	0.001	0.999	0.000
K14.3 Hypertrophy of tongue papillae	0.001	0.999	0.000
K14.2 Median rhomboid glossitis	0.001	0.999	0.000
M86.1 Other acute osteomyelitis	0.001	0.999	0.000
Q43.1 Hirschsprung's disease	0.001	0.999	0.000
Z31.2 In vitro fertilisation	0.000	0.999	0.001
M86.49 Chronic osteomyelitis with draining sinus (Site unspecified)	0.001	0.999	0.000
M86.48 Chronic osteomyelitis with draining sinus (Other)	0.001	0.999	0.000
M86.47 Chronic osteomyelitis with draining sinus (Ankle and foot)	0.001	0.999	0.000
M86.45 Chronic osteomyelitis with draining sinus (Pelvic region and thigh)	0.001	0.999	0.000
M86.44 Chronic osteomyelitis with draining sinus (Hand)	0.001	0.999	0.000
M86.43 Chronic osteomyelitis with draining sinus (Forearm)	0.001	0.999	0.000
M86.42 Chronic osteomyelitis with draining sinus (Upper arm)	0.001	0.999	0.000
M86.41 Chronic osteomyelitis with draining sinus (Shoulder region)	0.001	0.999	0.000
M86.40 Chronic osteomyelitis with draining sinus (Multiple sites)	0.001	0.999	0.000
E21.4 Other specified disorders of parathyroid gland	0.000	0.999	0.001
O30.0 Twin pregnancy	0.000	0.999	0.001
D22.6 Melanocytic naevi of upper limb, including shoulder	0.001	0.999	0.000
K14.1 Geographic tongue	0.001	0.999	0.000
N87.1 Moderate cervical dysplasia	0.000	0.999	0.001
Q38 Other congenital malformations of tongue, mouth and pharynx	0.001	0.999	0.000
G31.0 Circumscribed brain atrophy	0.000	0.999	0.001
G51.3 Clonic hemifacial spasm	0.001	0.999	0.000
G99.0 Autonomic neuropathy in endocrine and metabolic diseases	0.000	0.999	0.001
Q45.3 Other congenital malformations of pancreas and pancreatic duct	0.001	0.999	0.000
S52.41 Fracture of shafts of both ulna and radius (open)	0.000	0.999	0.001
B16.2 Acute hepatitis B without delta-agent with hepatic coma	0.001	0.999	0.000
B16.1 Acute hepatitis B with delta-agent (coinfection) without hepatic coma	0.001	0.999	0.000
B16.0 Acute hepatitis B with delta-agent (coinfection) with hepatic coma	0.001	0.999	0.000
N04.9 Unspecified	0.000	0.999	0.001
M86.09 Acute haematogenous osteomyelitis (Site unspecified)	0.001	0.999	0.000
M86.08 Acute haematogenous osteomyelitis (Other)	0.001	0.999	0.000
M86.07 Acute haematogenous osteomyelitis (Ankle and foot)	0.001	0.999	0.000
M86.06 Acute haematogenous osteomyelitis (Lower leg)	0.001	0.999	0.000
M86.05 Acute haematogenous osteomyelitis (Pelvic region and thigh)	0.001	0.999	0.000
M86.04 Acute haematogenous osteomyelitis (Hand)	0.001	0.999	0.000
M86.03 Acute haematogenous osteomyelitis (Forearm)	0.001	0.999	0.000
M86.02 Acute haematogenous osteomyelitis (Upper arm)	0.001	0.999	0.000
M86.01 Acute haematogenous osteomyelitis (Shoulder region)	0.001	0.999	0.000
M86.00 Acute haematogenous osteomyelitis (Multiple sites)	0.001	0.999	0.000
M86.29 Subacute osteomyelitis (Site unspecified)	0.001	0.999	0.000
M86.28 Subacute osteomyelitis (Other)	0.001	0.999	0.000
M86.27 Subacute osteomyelitis (Ankle and foot)	0.001	0.999	0.000
M86.26 Subacute osteomyelitis (Lower leg)	0.001	0.999	0.000
M86.25 Subacute osteomyelitis (Pelvic region and thigh)	0.001	0.999	0.000
M86.24 Subacute osteomyelitis (Hand)	0.001	0.999	0.000
M86.23 Subacute osteomyelitis (Forearm)	0.001	0.999	0.000
M86.22 Subacute osteomyelitis (Upper arm)	0.001	0.999	0.000
M86.21 Subacute osteomyelitis (Shoulder region)	0.001	0.999	0.000
M86.20 Subacute osteomyelitis (Multiple sites)	0.001	0.999	0.000
M86.39 Chronic multifocal osteomyelitis (Site unspecified)	0.001	0.999	0.000
M86.38 Chronic multifocal osteomyelitis (Other)	0.001	0.999	0.000
M86.37 Chronic multifocal osteomyelitis (Ankle and foot)	0.001	0.999	0.000
M86.36 Chronic multifocal osteomyelitis (Lower leg)	0.001	0.999	0.000
M86.35 Chronic multifocal osteomyelitis (Pelvic region and thigh)	0.001	0.999	0.000
M86.34 Chronic multifocal osteomyelitis (Hand)	0.001	0.999	0.000
M86.33 Chronic multifocal osteomyelitis (Forearm)	0.001	0.999	0.000
M86.32 Chronic multifocal osteomyelitis (Upper arm)	0.001	0.999	0.000
M86.31 Chronic multifocal osteomyelitis (Shoulder region)	0.001	0.999	0.000
M86.30 Chronic multifocal osteomyelitis (Multiple sites)	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations