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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs4783278
log Bayes Factor = 8.34675
Chromosome 16   position 82,829,767  (GRCh37) Explore rs4783278 on Ensembl!
Variant rs4783278 is part of Cluster X0080

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
M50-M54 Other dorsopathies
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
M54 Dorsalgia
0.999 0.001 0.000
I10-I15 Hypertensive diseases
0.998 0.002 0.000
I10 Essential (primary) hypertension
0.997 0.003 0.000
M05-M14 Inflammatory polyarthropathies
0.996 0.004 0.000
M54.5 Low back pain
0.996 0.004 0.000
M45-M49 Spondylopathies
0.996 0.004 0.000
M06 Other rheumatoid arthritis
0.995 0.005 0.000
M06.9 Rheumatoid arthritis, unspecified
0.993 0.007 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.992 0.008 0.000
M54.56 Low back pain (Lumbar region)
0.992 0.008 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.991 0.009 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.990 0.010 0.000
M47 Spondylosis
0.983 0.017 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.982 0.018 0.000
Chapter I Certain infectious and parasitic diseases
0.974 0.026 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.948 0.052 0.000
I74 Arterial embolism and thrombosis
0.948 0.052 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.941 0.059 0.000
M54.2 Cervicalgia
0.939 0.061 0.000
S00-S09 Injuries to the head
0.924 0.076 0.000
M50 Cervical disk disorders
0.918 0.082 0.000
M47.9 Spondylosis, unspecified
0.917 0.083 0.000
E70-E90 Metabolic disorders
0.914 0.086 0.000
Chapter X Diseases of the respiratory system
0.912 0.088 0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.904 0.096 0.000
S01 Open wound of head
0.896 0.104 0.000
M54.22 Cervicalgia (Cervical region)
0.892 0.108 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.892 0.108 0.000
E20-E35 Disorders of other endocrine glands
0.892 0.108 0.000
M86-M90 Other osteopathies
0.890 0.110 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.890 0.110 0.000
M48 Other spondylopathies
0.886 0.114 0.000
M47.2 Other spondylosis with radiculopathy
0.881 0.119 0.000
M06.98 Rheumatoid arthritis, unspecified (Other)
0.875 0.125 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.873 0.127 0.000
M47.8 Other spondylosis
0.873 0.127 0.000
M54.58 Low back pain (Sacral and sacrococcygeal region)
0.872 0.128 0.000
Chapter XX External causes of morbidity and mortality
0.870 0.130 0.000
E50-E64 Other nutritional deficiencies
0.869 0.131 0.000
I73 Other peripheral vascular diseases
0.868 0.132 0.000
I27 Other pulmonary heart diseases
0.867 0.133 0.000
S90-S99 Injuries to the ankle and foot
0.866 0.134 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.865 0.135 0.000
M50.0 Cervical disk disorder with myelopathy
0.863 0.137 0.000
I05-I09 Chronic rheumatic heart diseases
0.855 0.145 0.000
I72 Other aneurysm
0.852 0.148 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.846 0.154 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.846 0.154 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.839 0.161 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.839 0.161 0.000
M40-M43 Deforming dorsopathies
0.838 0.162 0.000
M54.1 Radiculopathy
0.836 0.164 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.831 0.169 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.829 0.171 0.000
E40-E46 Malnutrition
0.827 0.173 0.000
M47.96 Spondylosis, unspecified (Lumbar region)
0.826 0.174 0.000
A30-A49 Other bacterial diseases
0.822 0.178 0.000
M06.0 Seronegative rheumatoid arthritis
0.818 0.182 0.000
M91-M94 Chondropathies
0.816 0.184 0.000
I74.5 Embolism and thrombosis of iliac artery
0.815 0.185 0.000
E65-E68 Obesity and other hyperalimentation
0.813 0.187 0.000
M51 Other intervertebral disk disorders
0.812 0.188 0.000
J09-J18 Influenza and pneumonia
0.809 0.191 0.000
I73.9 Peripheral vascular disease, unspecified
0.808 0.192 0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.807 0.193 0.000
M20-M25 Other joint disorders
0.806 0.194 0.000
M06.3 Rheumatoid nodule
0.801 0.199 0.000
M45 Ankylosing spondylitis
0.800 0.200 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.800 0.200 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.799 0.201 0.000
M47.92 Spondylosis, unspecified (Cervical region)
0.797 0.203 0.000
S32 Fracture of lumbar spine and pelvis
0.796 0.204 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.796 0.204 0.000
E78.2 Mixed hyperlipidaemia
0.795 0.205 0.000
I71 Aortic aneurysm and dissection
0.795 0.205 0.000
Chapter VI Diseases of the nervous system
0.792 0.208 0.000
M48.0 Spinal stenosis
0.792 0.208 0.000
I77 Other disorders of arteries and arterioles
0.789 0.211 0.000
I26 Pulmonary embolism
0.789 0.211 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.788 0.212 0.000
S01.4 Open wound of cheek and temporomandibular area
0.787 0.213 0.000
S01.5 Open wound of lip and oral cavity
0.787 0.213 0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.786 0.214 0.000
E85 Amyloidosis
0.783 0.217 0.000
B00 Herpesviral [herpes simplex] infections
0.783 0.217 0.000
M47.22 Other spondylosis with radiculopathy (Cervical region)
0.782 0.218 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.781 0.219 0.000
M89 Other disorders of bone
0.781 0.219 0.000
M54.50 Low back pain (Multiple sites in spine)
0.779 0.221 0.000
M50.1 Cervical disk disorder with radiculopathy
0.778 0.222 0.000
M54.6 Pain in thoracic spine
0.777 0.223 0.000
I78 Diseases of capillaries
0.774 0.226 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.769 0.231 0.000
M14 Arthropathies in other diseases classified elsewhere
0.769 0.231 0.000
I27.0 Primary pulmonary hypertension
0.768 0.232 0.000
B99-B99 Other infectious diseases
0.763 0.236 0.000
M46 Other inflammatory spondylopathies
0.762 0.238 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.762 0.238 0.000
J90-J94 Other diseases of pleura
0.762 0.238 0.000
S20-S29 Injuries to the thorax
0.762 0.238 0.000
I08 Multiple valve diseases
0.761 0.239 0.000
M54.3 Sciatica
0.761 0.239 0.000
E61 Deficiency of other nutrient elements
0.757 0.243 0.000
E88 Other metabolic disorders
0.757 0.243 0.000
J84 Other interstitial pulmonary diseases
0.754 0.246 0.000
S10-S19 Injuries to the neck
0.754 0.246 0.000
B24 Unspecified human immunodeficiency virus [HIV] disease
0.754 0.246 0.000
V20-V29 Motorcycle rider injured in transport accident
0.753 0.247 0.000
B15-B19 Viral hepatitis
0.753 0.247 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.752 0.248 0.000
M54.4 Lumbago with sciatica
0.752 0.248 0.000
M00-M03 Infectious arthropathies
0.752 0.248 0.000
E34 Other endocrine disorders
0.751 0.249 0.000
S05 Injury of eye and orbit
0.749 0.250 0.000
B35-B49 Mycoses
0.749 0.251 0.000
E78.5 Hyperlipidaemia, unspecified
0.749 0.251 0.000
T50.9 Other and unspecified drugs, medicaments and biological substances
0.747 0.253 0.000
M47.80 Other spondylosis (Multiple sites in spine)
0.745 0.255 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.744 0.256 0.000
I11 Hypertensive heart disease
0.743 0.257 0.000
E53 Deficiency of other B group vitamins
0.742 0.258 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.741 0.259 0.000
M43 Other deforming dorsopathies
0.740 0.260 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.740 0.260 0.000
E10-E14 Diabetes mellitus
0.740 0.260 0.000
M10 Gout
0.739 0.261 0.000
M07 Psoriatic and enteropathic arthropathies
0.738 0.262 0.000
E78.4 Other hyperlipidaemia
0.732 0.268 0.000
E23 Hypofunction and other disorders of pituitary gland
0.731 0.269 0.000
J86 Pyothorax
0.731 0.269 0.000
M47.90 Spondylosis, unspecified (Multiple sites in spine)
0.731 0.269 0.000
M22 Disorders of patella
0.730 0.270 0.000
T42.4 Benzodiazepines
0.730 0.270 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.728 0.272 0.000
A80-A89 Viral infections of the central nervous system
0.728 0.272 0.000
M06.4 Inflammatory polyarthropathy
0.726 0.274 0.000
J13 Pneumonia due to Streptococcus pneumoniae
0.726 0.274 0.000
E78.1 Pure hyperglyceridaemia
0.724 0.276 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.723 0.277 0.000
S01.8 Open wound of other parts of head
0.722 0.278 0.000
M60-M63 Disorders of muscles
0.722 0.278 0.000
B65-B83 Helminthiases
0.719 0.281 0.000
M11 Other crystal arthropathies
0.719 0.281 0.000
E22 Hyperfunction of pituitary gland
0.719 0.281 0.000
X60-X84 Intentional self-harm
0.719 0.281 0.000
M80-M85 Disorders of bone density and structure
0.718 0.282 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
I72.3 Aneurysm of iliac artery
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
M54.8 Other dorsalgia
0.717 0.283 0.000
M54.0 Panniculitis affecting regions of neck and back
0.717 0.283 0.000
I15 Secondary hypertension
0.716 0.284 0.000
I13 Hypertensive heart and renal disease
0.715 0.285 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.715 0.285 0.000
S91 Open wound of ankle and foot
0.715 0.285 0.000
S92 Fracture of foot, except ankle
0.715 0.285 0.000
M12 Other specific arthropathies
0.714 0.286 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.714 0.286 0.000
M08 Juvenile arthritis
0.714 0.286 0.000
M54.55 Low back pain (Thoracolumbar region)
0.714 0.286 0.000
M54.54 Low back pain-Thoracic
0.714 0.286 0.000
M54.53 Low back pain-Cervicothoracic
0.714 0.286 0.000
M54.52 Low back pain-Cervical
0.714 0.286 0.000
M54.51 Low back pain-Occipit-atl-axl
0.714 0.286 0.000
M49 Spondylopathies in diseases classified elsewhere
0.714 0.286 0.000
M06.8 Other specified rheumatoid arthritis
0.713 0.286 0.000
M06.2 Rheumatoid bursitis
0.713 0.286 0.000
M06.1 Adult-onset Still's disease
0.713 0.286 0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.712 0.288 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.711 0.289 0.000
M47.1 Other spondylosis with myelopathy
0.711 0.289 0.000
Chapter XXII Codes for special purposes
0.710 0.290 0.000
Q80-Q89 Other congenital malformations
0.710 0.290 0.000
E46 Unspecified protein-energy malnutrition
0.709 0.291 0.000
G51 Facial nerve disorders
0.708 0.292 0.000
M47.87 Other spondylosis (Lumbosacral region)
0.707 0.293 0.000
J94 Other pleural conditions
0.707 0.293 0.000
Chapter V Mental and behavioural disorders
0.705 0.295 0.000
M47.0 Anterior spinal and vertebral artery compression syndromes
0.705 0.295 0.000
M47.86 Other spondylosis (Lumbar region)
0.704 0.296 0.000
T33-T35 Frostbite
0.704 0.296 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.704 0.296 0.000
T00-T07 Injuries involving multiple body regions
0.704 0.296 0.000
S06 Intracranial injury
0.704 0.296 0.000
T21 Burn and corrosion of trunk
0.703 0.297 0.000
J84.1 Other interstitial pulmonary diseases with fibrosis
0.703 0.297 0.000
L60-L75 Disorders of skin appendages
0.702 0.298 0.000
S50-S59 Injuries to the elbow and forearm
0.700 0.299 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.700 0.300 0.000
M24 Other specific joint derangements
0.700 0.300 0.000
M54.29 Cervicalgia-Site unspe
0.699 0.301 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.699 0.301 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.699 0.301 0.000
B50-B64 Protozoal diseases
0.699 0.301 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.699 0.301 0.000
A75-A79 Rickettsioses
0.699 0.301 0.000
A70-A74 Other diseases caused by chlamydiae
0.699 0.301 0.000
A65-A69 Other spirochaetal diseases
0.699 0.301 0.000
A20-A28 Certain zoonotic bacterial diseases
0.699 0.301 0.000
A15-A19 Tuberculosis
0.699 0.301 0.000
E29 Testicular dysfunction
0.697 0.303 0.000
G90-G99 Other disorders of the nervous system
0.694 0.306 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.693 0.307 0.000
M47.27 Other spondylosis with radiculopathy (Lumbosacral region)
0.692 0.308 0.000
M54.59 Low back pain (Site unspecified)
0.692 0.308 0.000
I27.8 Other specified pulmonary heart diseases
0.692 0.308 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.692 0.308 0.000
M48.06 Spinal stenosis (Lumbar region)
0.691 0.309 0.000
E85.9 Amyloidosis, unspecified
0.690 0.310 0.000
E78.9 Disorder of lipoprotein metabolism, unspecified
0.690 0.310 0.000
I73.8 Other specified peripheral vascular diseases
0.689 0.311 0.000
S01.2 Open wound of nose
0.687 0.313 0.000
B02 Zoster [herpes zoster]
0.687 0.313 0.000
J85 Abscess of lung and mediastinum
0.687 0.313 0.000
S32.4 Fracture of acetabulum
0.687 0.313 0.000
B95-B98 Bacterial, viral and other infectious agents
0.686 0.314 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.685 0.315 0.000
M86 Osteomyelitis
0.685 0.315 0.000
B00.1 Herpesviral vesicular dermatitis
0.684 0.316 0.000
Y57 Other and unspecified drugs and medicaments
0.683 0.317 0.000
I27.9 Pulmonary heart disease, unspecified
0.683 0.317 0.000
M30 Polyarteritis nodosa and related conditions
0.682 0.318 0.000
S01.7 Multiple open wounds of head
0.681 0.319 0.000
S09 Other and unspecified injuries of head
0.680 0.320 0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis
0.680 0.320 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.680 0.320 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.680 0.320 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.680 0.320 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.680 0.320 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.680 0.320 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.680 0.320 0.000
T36 Poisoning by systemic antibiotics
0.680 0.320 0.000
I74.9 Embolism and thrombosis of unspecified artery
0.680 0.320 0.000
I74.8 Embolism and thrombosis of other arteries
0.680 0.320 0.000
I74.4 Embolism and thrombosis of arteries of extremities, unspecified
0.680 0.320 0.000
I74.1 Embolism and thrombosis of other and unspecified parts of aorta
0.680 0.320 0.000
I74.0 Embolism and thrombosis of abdominal aorta
0.680 0.320 0.000
I26.9 Pulmonary embolism without mention of acute cor pulmonale
0.680 0.320 0.000
I99 Other and unspecified disorders of circulatory system
0.679 0.321 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.678 0.322 0.000
E78.0 Pure hypercholesterolaemia
0.678 0.322 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.678 0.322 0.000
M48.5 Collapsed vertebra, not elsewhere classified
0.678 0.322 0.000
E74 Other disorders of carbohydrate metabolism
0.677 0.322 0.000
E61.1 Iron deficiency
0.677 0.323 0.000
E11 Non-insulin-dependent diabetes mellitus
0.677 0.323 0.000
M54.9 Dorsalgia, unspecified
0.676 0.324 0.000
I08.1 Disorders of both mitral and tricuspid valves
0.676 0.324 0.000
I28 Other diseases of pulmonary vessels
0.674 0.325 0.000
M53 Other dorsopathies, not elsewhere classified
0.674 0.326 0.000
M54.28 Cervicalgia-Sacral/sacrococ
0.673 0.326 0.000
M54.27 Cervicalgia-Lumbosacral
0.673 0.326 0.000
M54.26 Cervicalgia-Lumbar
0.673 0.326 0.000
M54.25 Cervicalgia-Thoracolumbar
0.673 0.326 0.000
M54.24 Cervicalgia-Thoracic
0.673 0.326 0.000
M54.23 Cervicalgia (Cervicothoracic region)
0.673 0.326 0.000
M54.21 Cervicalgia (Occipito-atlanto-axial region)
0.673 0.326 0.000
M54.20 Cervicalgia-Mult site
0.673 0.326 0.000
S01.3 Open wound of ear
0.673 0.326 0.000
M51.2 Other specified intervertebral disk displacement
0.673 0.327 0.000
S32.0 Fracture of lumbar vertebra
0.673 0.327 0.000
M50.3 Other cervical disk degeneration
0.672 0.327 0.000
M87 Osteonecrosis
0.672 0.328 0.000
S80-S89 Injuries to the knee and lower leg
0.671 0.329 0.000
M54.17 Radiculopathy (Lumbosacral region)
0.671 0.329 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.670 0.329 0.000
S01.9 Open wound of head, part unspecified
0.670 0.330 0.000
V23 Motorcycle rider injured in collision with car, pick-up truck or van
0.670 0.330 0.000
M54.12 Radiculopathy (Cervical region)
0.670 0.330 0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.670 0.330 0.000
M94 Other disorders of cartilage
0.670 0.330 0.000
M43.1 Spondylolisthesis
0.669 0.331 0.000
M89.9 Disorder of bone, unspecified
0.669 0.331 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.668 0.332 0.000
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.668 0.332 0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere
0.667 0.333 0.000
M06.32 Rheumatoid nodule (Upper arm)
0.667 0.333 0.000
I77.8 Other specified disorders of arteries and arterioles
0.667 0.333 0.000
M51.9 Intervertebral disk disorder, unspecified
0.666 0.334 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.666 0.334 0.000
A41 Other septicaemia
0.665 0.335 0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level
0.663 0.337 0.000
I71.0 Dissection of aorta [any part]
0.663 0.337 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.663 0.337 0.000
S08 Traumatic amputation of part of head
0.663 0.337 0.000
S07 Crushing injury of head
0.663 0.337 0.000
S04 Injury of cranial nerves
0.663 0.337 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.663 0.337 0.000
W50-W64 Exposure to animate mechanical forces
0.663 0.337 0.000
M25 Other joint disorders, not elsewhere classified
0.662 0.338 0.000
E73 Lactose intolerance
0.661 0.339 0.000
J86.9 Pyothorax without fistula
0.661 0.339 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.660 0.339 0.000
X10-X19 Contact with heat and hot substances
0.659 0.341 0.000
M50.9 Cervical disk disorder, unspecified
0.658 0.342 0.000
M50.8 Other cervical disk disorders
0.658 0.342 0.000
M47.98 Spondylosis, unspecified (Sacral and sacrococcygeal region)
0.658 0.342 0.000
M47.95 Spondylosis, unspecified (Thoracolumbar region)
0.658 0.342 0.000
M47.94 Spondylosis, unspecified (Thoracic region)
0.658 0.342 0.000
M47.93 Spondylosis, unspecified (Cervicothoracic region)
0.658 0.342 0.000
M47.91 Spondylosis, unspecified (Occipito-atlanto-axial region)
0.658 0.342 0.000
M47.82 Other spondylosis (Cervical region)
0.657 0.343 0.000
I08.3 Combined disorders of mitral, aortic and tricuspid valves
0.657 0.343 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.656 0.343 0.000
A49 Bacterial infection of unspecified site
0.655 0.345 0.000
E84 Cystic fibrosis
0.655 0.345 0.000
E79 Disorders of purine and pyrimidine metabolism
0.655 0.345 0.000
E77 Disorders of glycoprotein metabolism
0.655 0.345 0.000
E76 Disorders of glycosaminoglycan metabolism
0.655 0.345 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.655 0.345 0.000
E72 Other disorders of amino-acid metabolism
0.655 0.345 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.655 0.345 0.000
E70 Disorders of aromatic amino-acid metabolism
0.655 0.345 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.655 0.345 0.000
E26 Hyperaldosteronism
0.655 0.345 0.000
Y00-Y09 Assault
0.655 0.345 0.000
J15 Bacterial pneumonia, not elsewhere classified
0.655 0.345 0.000
B08 Other viral infections characterised by skin and mucous membrane lesions, not elsewhere classified
0.654 0.346 0.000
T24 Burn and corrosion of hip and lower limb, except ankle and foot
0.654 0.346 0.000
L91 Hypertrophic disorders of skin
0.654 0.346 0.000
V40-V49 Car occupant injured in transport accident
0.654 0.346 0.000
J00-J06 Acute upper respiratory infections
0.653 0.347 0.000
I77.6 Arteritis, unspecified
0.652 0.348 0.000
E53.8 Deficiency of other specified B group vitamins
0.651 0.349 0.000
M45.X0 Ankylosing spondylitis (Multiple sites in spine)
0.650 0.350 0.000
E66 Obesity
0.649 0.351 0.000
L40-L45 Papulosquamous disorders
0.649 0.351 0.000
S40-S49 Injuries to the shoulder and upper arm
0.649 0.351 0.000
T79-T79 Certain early complications of trauma
0.647 0.353 0.000
L89 Decubitus ulcer
0.647 0.353 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.647 0.353 0.000
M88 Paget's disease of bone [osteitis deformans]
0.646 0.354 0.000
I72.4 Aneurysm of artery of lower extremity
0.646 0.354 0.000
S01.1 Open wound of eyelid and periocular area
0.646 0.354 0.000
I70 Atherosclerosis
0.645 0.355 0.000
S32.7 Multiple fractures of lumbar spine and pelvis
0.643 0.357 0.000
I72.8 Aneurysm of other specified arteries
0.643 0.357 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.642 0.357 0.000
T40.6 Other and unspecified narcotics
0.641 0.359 0.000
I78.0 Hereditary haemorrhagic telangiectasia
0.641 0.359 0.000
A40 Streptococcal septicaemia
0.640 0.360 0.000
X50-X57 Overexertion, travel and privation
0.640 0.360 0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified
0.640 0.360 0.000
B00.5 Herpesviral ocular disease
0.640 0.360 0.000
E78.6 Lipoprotein deficiency
0.639 0.361 0.000
E78.3 Hyperchylomicronaemia
0.639 0.361 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.639 0.361 0.000
E32 Diseases of thymus
0.639 0.361 0.000
E31 Polyglandular dysfunction
0.639 0.361 0.000
E30 Disorders of puberty, not elsewhere classified
0.639 0.361 0.000
E25 Adrenogenital disorders
0.639 0.361 0.000
E20 Hypoparathyroidism
0.639 0.361 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.639 0.361 0.000
S02 Fracture of skull and facial bones
0.639 0.361 0.000
M47.26 Other spondylosis with radiculopathy (Lumbar region)
0.639 0.361 0.000
E11.9 Without complications
0.639 0.361 0.000
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis
0.638 0.362 0.000
S37 Injury of urinary and pelvic organs
0.638 0.362 0.000
S36 Injury of intra-abdominal organs
0.638 0.362 0.000
S35 Injury of blood vessels at abdomen, lower back and pelvis level
0.638 0.362 0.000
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level
0.638 0.362 0.000
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis
0.638 0.362 0.000
S31 Open wound of abdomen, lower back and pelvis
0.638 0.362 0.000
L20-L30 Dermatitis and eczema
0.638 0.362 0.000
M47.97 Spondylosis, unspecified (Lumbosacral region)
0.637 0.363 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.637 0.363 0.000
M15-M19 Arthrosis
0.637 0.363 0.000
T43.5 Other and unspecified antipsychotics and neuroleptics
0.636 0.363 0.000
W00-W19 Falls
0.636 0.364 0.000
S29 Other and unspecified injuries of thorax
0.636 0.364 0.000
M48.9 Spondylopathy, unspecified
0.635 0.364 0.000
M48.8 Other specified spondylopathies
0.635 0.364 0.000
M48.4 Fatigue fracture of vertebra
0.635 0.364 0.000
M48.3 Traumatic spondylopathy
0.635 0.364 0.000
M48.2 Kissing spine
0.635 0.364 0.000
M48.1 Ankylosing hyperostosis [Forestier]
0.635 0.364 0.000
Q50-Q56 Congenital malformations of genital organs
0.634 0.366 0.000
E78.8 Other disorders of lipoprotein metabolism
0.634 0.366 0.000
E65 Localised adiposity
0.634 0.366 0.000
M54.19 Radiculopathy (Site unspecified)
0.633 0.367 0.000
M47.29 Other spondylosis with radiculopathy (Site unspecified)
0.632 0.368 0.000
M47.28 Other spondylosis with radiculopathy (Sacral and sacrococcygeal region)
0.632 0.368 0.000
M47.25 Other spondylosis with radiculopathy (Thoracolumbar region)
0.632 0.368 0.000
M47.24 Other spondylosis with radiculopathy (Thoracic region)
0.632 0.368 0.000
M47.23 Other spondylosis with radiculopathy (Cervicothoracic region)
0.632 0.368 0.000
M47.21 Other spondylosis with radiculopathy (Occipito-atlanto-axial region)
0.632 0.368 0.000
M47.20 Other spondylosis with radiculopathy (Multiple sites in spine)
0.632 0.368 0.000
M43.16 Spondylolisthesis (Lumbar region)
0.632 0.368 0.000
J95-J99 Other diseases of the respiratory system
0.632 0.368 0.000
V10-V19 Pedal cyclist injured in transport accident
0.629 0.371 0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.629 0.371 0.000
J10 Influenza due to identified influenza virus
0.629 0.371 0.000
S90 Superficial injury of ankle and foot
0.628 0.372 0.000
M89.8 Other specified disorders of bone
0.628 0.372 0.000
E27 Other disorders of adrenal gland
0.627 0.373 0.000
B06 Rubella [German measles]
0.626 0.374 0.000
B05 Measles
0.626 0.374 0.000
B01 Varicella [chickenpox]
0.626 0.374 0.000
B09 Unspecified viral infection characterised by skin and mucous membrane lesions
0.626 0.374 0.000
B04 Monkeypox
0.626 0.374 0.000
B03 Smallpox
0.626 0.374 0.000
M47.88 Other spondylosis (Sacral and sacrococcygeal region)
0.626 0.374 0.000
M47.85 Other spondylosis (Thoracolumbar region)
0.626 0.374 0.000
M47.84 Other spondylosis (Thoracic region)
0.626 0.374 0.000
M47.83 Other spondylosis (Cervicothoracic region)
0.626 0.374 0.000
M47.81 Other spondylosis (Occipito-atlanto-axial region)
0.626 0.374 0.000
M48.07 Spinal stenosis (Lumbosacral region)
0.626 0.374 0.000
M54.37 Sciatica (Lumbosacral region)
0.626 0.374 0.000
J92 Pleural plaque
0.626 0.374 0.000
Q00-Q07 Congenital malformations of the nervous system
0.625 0.374 0.000
S05.8 Other injuries of eye and orbit
0.624 0.376 0.000
M90 Osteopathies in diseases classified elsewhere
0.624 0.376 0.000
L91.8 Other hypertrophic disorders of skin
0.624 0.376 0.000
J94.8 Other specified pleural conditions
0.624 0.376 0.000
Y35-Y36 Legal intervention and operations of war
0.624 0.376 0.000
Y10-Y34 Event of undetermined intent
0.624 0.376 0.000
X85-X99 Assault
0.624 0.376 0.000
X30-X39 Exposure to forces of nature
0.624 0.376 0.000
X00-X09 Exposure to smoke, fire and flames
0.624 0.376 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.624 0.376 0.000
W75-W84 Other accidental threats to breathing
0.624 0.376 0.000
W65-W74 Accidental drowning and submersion
0.624 0.376 0.000
V98-V99 Other and unspecified transport accidents
0.624 0.376 0.000
V95-V97 Air and space transport accidents
0.624 0.376 0.000
V90-V94 Water transport accidents
0.624 0.376 0.000
V70-V79 Bus occupant injured in transport accident
0.624 0.376 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.624 0.376 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.624 0.376 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.624 0.376 0.000
V01-V09 Pedestrian injured in transport accident
0.624 0.376 0.000
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.623 0.377 0.000
E64 Sequelae of malnutrition and other nutritional deficiencies
0.623 0.377 0.000
E63 Other nutritional deficiencies
0.623 0.377 0.000
E56 Other vitamin deficiencies
0.623 0.377 0.000
E51 Thiamine deficiency
0.623 0.377 0.000
E50 Vitamin A deficiency
0.623 0.377 0.000
E60 Dietary zinc deficiency
0.623 0.377 0.000
E59 Dietary selenium deficiency
0.623 0.377 0.000
E58 Dietary calcium deficiency
0.623 0.377 0.000
E54 Ascorbic acid deficiency
0.623 0.377 0.000
E52 Niacin deficiency [pellagra]
0.623 0.377 0.000
M05 Seropositive rheumatoid arthritis
0.623 0.377 0.000
I73.1 Thromboangiitis obliterans [Buerger]
0.623 0.377 0.000
I07 Rheumatic tricuspid valve diseases
0.622 0.377 0.000
I27.2 Other secondary pulmonary hypertension
0.622 0.378 0.000
I27.1 Kyphoscoliotic heart disease
0.622 0.378 0.000
J84.9 Interstitial pulmonary disease, unspecified
0.622 0.378 0.000
S98 Traumatic amputation of ankle and foot
0.621 0.379 0.000
S97 Crushing injury of ankle and foot
0.621 0.379 0.000
S96 Injury of muscle and tendon at ankle and foot level
0.621 0.379 0.000
S95 Injury of blood vessels at ankle and foot level
0.621 0.379 0.000
S94 Injury of nerves at ankle and foot level
0.621 0.379 0.000
Y40 Systemic antibiotics
0.620 0.380 0.000
Y52 Agents primarily affecting the cardiovascular system
0.620 0.380 0.000
L10-L14 Bullous disorders
0.620 0.380 0.000
Y43 Primarily systemic agents
0.619 0.381 0.000
G70-G73 Diseases of myoneural junction and muscle
0.618 0.381 0.000
E83 Disorders of mineral metabolism
0.618 0.382 0.000
M54.64 Pain in thoracic spine (Thoracic region)
0.618 0.382 0.000
M22.4 Chondromalacia patellae
0.615 0.385 0.000
L73 Other follicular disorders
0.615 0.385 0.000
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.615 0.385 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.614 0.386 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.614 0.386 0.000
G51.0 Bell's palsy
0.614 0.386 0.000
I09 Other rheumatic heart diseases
0.613 0.387 0.000
I06 Rheumatic aortic valve diseases
0.613 0.387 0.000
B25-B34 Other viral diseases
0.613 0.387 0.000
V80-V89 Other land transport accidents
0.613 0.387 0.000
B99 Other and unspecified infectious diseases
0.612 0.388 0.000
E24 Cushing's syndrome
0.612 0.388 0.000
M21 Other acquired deformities of limbs
0.612 0.388 0.000
I72.9 Aneurysm of unspecified site
0.611 0.389 0.000
I72.6 Aneurysm and dissection of vertebral artery
0.611 0.389 0.000
I72.5 Aneurysm and dissection of other precerebral arteries
0.611 0.389 0.000
I72.2 Aneurysm of renal artery
0.611 0.389 0.000
I72.1 Aneurysm of artery of upper extremity
0.611 0.389 0.000
I72.0 Aneurysm of carotid artery
0.611 0.389 0.000
V23.4 Driver injured in traffic accident
0.610 0.390 0.000
M48.00 Spinal stenosis (Multiple sites in spine)
0.610 0.390 0.000
E23.2 Diabetes insipidus
0.610 0.390 0.000
L60 Nail disorders
0.610 0.390 0.000
M93 Other osteochondropathies
0.609 0.391 0.000
I77.9 Disorder of arteries and arterioles, unspecified
0.609 0.391 0.000
G59 Mononeuropathy in diseases classified elsewhere
0.609 0.391 0.000
E34.9 Endocrine disorder, unspecified
0.609 0.391 0.000
S32.40 Fracture of acetabulum (closed)
0.609 0.391 0.000
T23 Burn and corrosion of wrist and hand
0.608 0.391 0.000
S21 Open wound of thorax
0.608 0.392 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.607 0.393 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.607 0.393 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.607 0.393 0.000
Q35-Q37 Cleft lip and cleft palate
0.607 0.393 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.607 0.393 0.000
B23 Human immunodeficiency virus [HIV] disease resulting in other conditions
0.606 0.393 0.000
B22 Human immunodeficiency virus [HIV] disease resulting in other specified diseases
0.606 0.393 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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