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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs4789400
log Bayes Factor = 0.313519
Chromosome 17   position 74,997,897  (GRCh37) Explore rs4789400 on Ensembl!
Variant rs4789400 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
I34.0 Mitral (valve) insufficiency
0.000 0.457 0.543
I34 Nonrheumatic mitral valve disorders
0.000 0.464 0.536
I30-I52 Other forms of heart disease
0.000 0.483 0.517
I44 Atrioventricular and left bundle-branch block
0.000 0.493 0.507
I42 Cardiomyopathy
0.000 0.506 0.494
I44.7 Left bundle-branch block, unspecified
0.000 0.512 0.488
I34.1 Mitral (valve) prolapse
0.000 0.515 0.485
I46 Cardiac arrest
0.000 0.527 0.473
I44.1 Atrioventricular block, second degree
0.000 0.552 0.448
I44.3 Other and unspecified atrioventricular block
0.000 0.565 0.435
I42.0 Dilated cardiomyopathy
0.000 0.568 0.432
I46.9 Cardiac arrest, unspecified
0.000 0.569 0.431
I42.9 Cardiomyopathy, unspecified
0.000 0.570 0.430
I47 Paroxysmal tachycardia
0.000 0.582 0.418
I34.2 Nonrheumatic mitral (valve) stenosis
0.000 0.598 0.402
I43 Cardiomyopathy in diseases classified elsewhere
0.000 0.598 0.402
I36 Nonrheumatic tricuspid valve disorders
0.000 0.602 0.398
I30 Acute pericarditis
0.000 0.604 0.396
I47.2 Ventricular tachycardia
0.000 0.609 0.391
I42.2 Other hypertrophic cardiomyopathy
0.000 0.612 0.388
I42.6 Alcoholic cardiomyopathy
0.000 0.613 0.387
I49 Other cardiac arrhythmias
0.000 0.616 0.384
I34.8 Other nonrheumatic mitral valve disorders
0.000 0.617 0.383
I33 Acute and subacute endocarditis
0.000 0.623 0.376
I42.8 Other cardiomyopathies
0.000 0.626 0.374
I44.6 Other and unspecified fascicular block
0.000 0.629 0.371
I52 Other heart disorders in diseases classified elsewhere
0.000 0.629 0.371
I48 Atrial fibrillation and flutter
0.000 0.629 0.371
I41 Myocarditis in diseases classified elsewhere
0.000 0.629 0.371
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.000 0.629 0.371
I32 Pericarditis in diseases classified elsewhere
0.000 0.629 0.371
I34.9 Nonrheumatic mitral valve disorder, unspecified
0.000 0.629 0.371
I40 Acute myocarditis
0.000 0.633 0.367
I37 Pulmonary valve disorders
0.000 0.635 0.365
I44.5 Left posterior fascicular block
0.000 0.636 0.364
I42.7 Cardiomyopathy due to drugs and other external agents
0.000 0.639 0.361
I46.0 Cardiac arrest with successful resuscitation
0.000 0.640 0.359
I46.1 Sudden cardiac death, so described
0.000 0.644 0.355
I42.3 Endomyocardial (eosinophilic) disease
0.000 0.645 0.355
I42.4 Endocardial fibroelastosis
0.000 0.646 0.354
I42.1 Obstructive hypertrophic cardiomyopathy
0.000 0.657 0.342
I42.5 Other restrictive cardiomyopathy
0.000 0.659 0.341
I44.0 Atrioventricular block, first degree
0.000 0.659 0.341
I35 Nonrheumatic aortic valve disorders
0.000 0.662 0.338
I31 Other diseases of pericardium
0.000 0.668 0.332
I44.4 Left anterior fascicular block
0.000 0.674 0.326
I51 Complications and ill-defined descriptions of heart disease
0.000 0.674 0.326
I30.9 Acute pericarditis, unspecified
0.000 0.678 0.321
I49.5 Sick sinus syndrome
0.000 0.685 0.315
I44.2 Atrioventricular block, complete
0.000 0.685 0.315
I43.1 Cardiomyopathy in metabolic diseases
0.000 0.685 0.315
I36.1 Nonrheumatic tricuspid (valve) insufficiency
0.000 0.687 0.313
I51.8 Other ill-defined heart diseases
0.000 0.698 0.302
I35.1 Aortic (valve) insufficiency
0.000 0.699 0.301
I43.0 Cardiomyopathy in infectious and parasitic diseases classified elsewhere
0.000 0.699 0.301
I49.0 Ventricular fibrillation and flutter
0.000 0.702 0.298
I49.3 Ventricular premature depolarisation
0.000 0.704 0.296
I49.1 Atrial premature depolarisation
0.000 0.706 0.293
I35.2 Aortic (valve) stenosis with insufficiency
0.000 0.710 0.290
I47.0 Reentry ventricular arrhythmia
0.000 0.711 0.289
I43.2 Cardiomyopathy in nutritional diseases
0.000 0.712 0.288
I36.9 Nonrheumatic tricuspid valve disorder, unspecified
0.000 0.714 0.285
I36.8 Other nonrheumatic tricuspid valve disorders
0.000 0.714 0.285
I36.2 Nonrheumatic tricuspid (valve) stenosis with insufficiency
0.000 0.714 0.285
I36.0 Nonrheumatic tricuspid (valve) stenosis
0.000 0.714 0.285
I33.0 Acute and subacute infective endocarditis
0.000 0.715 0.284
I30.0 Acute nonspecific idiopathic pericarditis
0.000 0.716 0.284
I43.8 Cardiomyopathy in other diseases classified elsewhere
0.000 0.720 0.280
I30.1 Infective pericarditis
0.000 0.723 0.276
I49.2 Junctional premature depolarisation
0.000 0.724 0.276
I45 Other conduction disorders
0.000 0.725 0.275
I30.8 Other forms of acute pericarditis
0.000 0.725 0.274
I40.9 Acute myocarditis, unspecified
0.000 0.730 0.270
I37.1 Pulmonary valve insufficiency
0.000 0.730 0.270
I32.8 Pericarditis in other diseases classified elsewhere
0.000 0.734 0.266
I32.1 Pericarditis in other infectious and parasitic diseases classified elsewhere
0.000 0.734 0.266
I32.0 Pericarditis in bacterial diseases classified elsewhere
0.000 0.734 0.266
I39.8 Endocarditis, valve unspecified, in diseases classified elsewhere
0.000 0.734 0.266
I39.4 Multiple valve disorders in diseases classified elsewhere
0.000 0.734 0.266
I39.3 Pulmonary valve disorders in diseases classified elsewhere
0.000 0.734 0.266
I39.2 Tricuspid valve disorders in diseases classified elsewhere
0.000 0.734 0.266
I39.1 Aortic valve disorders in diseases classified elsewhere
0.000 0.734 0.266
I39.0 Mitral valve disorders in diseases classified elsewhere
0.000 0.734 0.266
I41.8 Myocarditis in other diseases classified elsewhere
0.000 0.734 0.266
I41.2 Myocarditis in other infectious and parasitic diseases classified elsewhere
0.000 0.734 0.266
I41.1 Myocarditis in viral diseases classified elsewhere
0.000 0.734 0.266
I41.0 Myocarditis in bacterial diseases classified elsewhere
0.000 0.734 0.266
I48.9 Atrial fibrillation and atrial flutter, unspecified
0.000 0.734 0.266
I48.4 Atypical atrial flutter
0.000 0.734 0.266
I48.3 Typical atrial flutter
0.000 0.734 0.266
I48.2 Chronic atrial fibrillation
0.000 0.734 0.266
I48.1 Persistent atrial fibrillation
0.000 0.734 0.266
I48.0 Paroxysmal atrial fibrillation
0.000 0.734 0.266
I52.8 Other heart disorders in other diseases classified elsewhere
0.000 0.734 0.266
I52.1 Other heart disorders in other infectious and parasitic diseases classified elsewhere
0.000 0.734 0.266
I52.0 Other heart disorders in bacterial diseases classified elsewhere
0.000 0.734 0.266
I40.8 Other acute myocarditis
0.000 0.736 0.263
I40.1 Isolated myocarditis
0.000 0.736 0.263
I49.8 Other specified cardiac arrhythmias
0.000 0.737 0.263
I47.9 Paroxysmal tachycardia, unspecified
0.000 0.737 0.263
I37.9 Pulmonary valve disorder, unspecified
0.000 0.738 0.262
I37.8 Other pulmonary valve disorders
0.000 0.738 0.262
I37.2 Pulmonary valve stenosis with insufficiency
0.000 0.738 0.262
I33.9 Acute endocarditis, unspecified
0.000 0.740 0.260
I31.3 Pericardial effusion (noninflammatory)
0.000 0.741 0.259
I31.0 Chronic adhesive pericarditis
0.000 0.745 0.254
I40.0 Infective myocarditis
0.000 0.748 0.252
I51.6 Cardiovascular disease, unspecified
0.000 0.752 0.248
I49.9 Cardiac arrhythmia, unspecified
0.000 0.752 0.248
I37.0 Pulmonary valve stenosis
0.000 0.753 0.247
I51.5 Myocardial degeneration
0.000 0.759 0.241
I31.8 Other specified diseases of pericardium
0.000 0.761 0.238
I31.2 Haemopericardium, not elsewhere classified
0.000 0.761 0.238
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.000 0.765 0.235
I51.2 Rupture of papillary muscle, not elsewhere classified
0.000 0.766 0.234
I51.0 Cardiac septal defect, acquired
0.000 0.769 0.231
I45.6 Preexcitation syndrome
0.000 0.769 0.231
I31.1 Chronic constrictive pericarditis
0.000 0.775 0.225
I51.4 Myocarditis, unspecified
0.000 0.777 0.223
I45.8 Other specified conduction disorders
0.000 0.785 0.215
I47.1 Supraventricular tachycardia
0.000 0.792 0.208
I35.9 Aortic valve disorder, unspecified
0.000 0.794 0.205
I45.2 Bifascicular block
0.000 0.795 0.205
I45.0 Right fascicular block
0.000 0.795 0.205
I45.4 Nonspecific intraventricular block
0.000 0.795 0.205
I51.3 Intracardiac thrombosis, not elsewhere classified
0.000 0.810 0.190
I49.4 Other and unspecified premature depolarisation
0.000 0.813 0.187
I51.9 Heart disease, unspecified
0.000 0.819 0.181
I45.3 Trifascicular block
0.000 0.826 0.173
I35.8 Other aortic valve disorders
0.000 0.828 0.171
I38 Endocarditis, valve unspecified
0.001 0.834 0.165
I45.9 Conduction disorder, unspecified
0.000 0.840 0.160
I45.5 Other specified heart block
0.000 0.842 0.158
I31.9 Disease of pericardium, unspecified
0.000 0.847 0.153
I50 Heart failure
0.000 0.894 0.106
I45.1 Other and unspecified right bundle-branch block
0.000 0.907 0.092
I51.7 Cardiomegaly
0.000 0.925 0.075
I35.0 Aortic (valve) stenosis
0.000 0.932 0.068
I50.0 Congestive heart failure
0.000 0.949 0.051
I50.9 Heart failure, unspecified
0.000 0.959 0.041
I50.1 Left ventricular failure
0.000 0.967 0.033
I08.1 Disorders of both mitral and tricuspid valves
0.000 0.976 0.024
I08 Multiple valve diseases
0.000 0.978 0.022
Chapter IX Diseases of the circulatory system
0.000 0.979 0.021
I05-I09 Chronic rheumatic heart diseases
0.000 0.979 0.021
I08.0 Disorders of both mitral and aortic valves
0.000 0.980 0.020
N31.9 Neuromuscular dysfunction of bladder, unspecified
0.000 0.981 0.019
I08.8 Other multiple valve diseases
0.000 0.981 0.019
I06 Rheumatic aortic valve diseases
0.000 0.983 0.016
I09 Other rheumatic heart diseases
0.000 0.984 0.016
I00-I02 Acute rheumatic fever
0.000 0.984 0.015
I08.9 Multiple valve disease, unspecified
0.000 0.985 0.015
I08.2 Disorders of both aortic and tricuspid valves
0.000 0.985 0.015
I71 Aortic aneurysm and dissection
0.000 0.986 0.014
I71.9 Aortic aneurysm of unspecified site, without mention of rupture
0.000 0.986 0.014
I70-I79 Diseases of arteries, arterioles and capillaries
0.000 0.986 0.014
I06.0 Rheumatic aortic stenosis
0.000 0.987 0.013
I10-I15 Hypertensive diseases
0.000 0.987 0.013
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.000 0.987 0.013
I60-I69 Cerebrovascular diseases
0.000 0.987 0.013
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.000 0.987 0.013
I09.9 Rheumatic heart disease, unspecified
0.000 0.987 0.012
I05 Rheumatic mitral valve diseases
0.000 0.987 0.012
I71.0 Dissection of aorta [any part]
0.000 0.988 0.012
I06.1 Rheumatic aortic insufficiency
0.000 0.988 0.012
I06.9 Rheumatic aortic valve disease, unspecified
0.000 0.988 0.012
I06.8 Other rheumatic aortic valve diseases
0.000 0.988 0.012
I07 Rheumatic tricuspid valve diseases
0.000 0.988 0.012
I09.8 Other specified rheumatic heart diseases
0.000 0.988 0.012
I09.2 Chronic rheumatic pericarditis
0.000 0.988 0.012
I09.1 Rheumatic diseases of endocardium, valve unspecified
0.000 0.988 0.012
I09.0 Rheumatic myocarditis
0.000 0.988 0.012
I06.2 Rheumatic aortic stenosis with insufficiency
0.000 0.988 0.012
I69 Sequelae of cerebrovascular disease
0.000 0.988 0.012
I00 Rheumatic fever without mention of heart involvement
0.000 0.988 0.011
I02 Rheumatic chorea
0.000 0.989 0.011
I01 Rheumatic fever with heart involvement
0.000 0.989 0.011
I63 Cerebral infarction
0.000 0.989 0.011
N81.1 Cystocele
0.011 0.989 0.000
I15 Secondary hypertension
0.000 0.989 0.011
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries
0.000 0.989 0.011
I27 Other pulmonary heart diseases
0.000 0.989 0.011
I71.8 Aortic aneurysm of unspecified site, ruptured
0.000 0.989 0.010
I71.5 Thoracoabdominal aortic aneurysm, ruptured
0.000 0.989 0.010
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture
0.000 0.989 0.010
I69.3 Sequelae of cerebral infarction
0.000 0.989 0.010
I71.3 Abdominal aortic aneurysm, ruptured
0.000 0.990 0.010
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries
0.000 0.990 0.010
I71.1 Thoracic aortic aneurysm, ruptured
0.000 0.990 0.010
I12 Hypertensive renal disease
0.000 0.990 0.010
I08.3 Combined disorders of mitral, aortic and tricuspid valves
0.000 0.990 0.010
I27.0 Primary pulmonary hypertension
0.000 0.990 0.010
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.000 0.990 0.010
I13 Hypertensive heart and renal disease
0.000 0.990 0.010
I62 Other nontraumatic intracranial haemorrhage
0.000 0.990 0.009
I68 Cerebrovascular disorders in diseases classified elsewhere
0.000 0.991 0.009
I70 Atherosclerosis
0.000 0.991 0.009
I05.8 Other mitral valve diseases
0.000 0.991 0.009
I72 Other aneurysm
0.000 0.991 0.009
I63.4 Cerebral infarction due to embolism of cerebral arteries
0.000 0.991 0.009
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.991 0.009
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.000 0.991 0.009
I15.9 Seconday hypertension, unspecified
0.000 0.991 0.009
I05.2 Mitral stenosis with insufficiency
0.000 0.991 0.009
I69.0 Sequelae of subarachnoid haemorrhage
0.000 0.991 0.009
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction
0.000 0.991 0.009
I69.2 Sequelae of other nontraumatic intracranial haemorrhage
0.000 0.991 0.009
I78 Diseases of capillaries
0.000 0.991 0.009
I07.9 Tricuspid valve disease, unspecified
0.000 0.991 0.008
I07.8 Other tricuspid valve diseases
0.000 0.991 0.008
I07.2 Tricuspid stenosis with insufficiency
0.000 0.991 0.008
I07.0 Tricuspid stenosis
0.000 0.991 0.008
I95-I99 Other and unspecified disorders of the circulatory system
0.000 0.991 0.009
I05.1 Rheumatic mitral insufficiency
0.000 0.991 0.008
I05.9 Mitral valve disease, unspecified
0.000 0.991 0.008
I28 Other diseases of pulmonary vessels
0.000 0.991 0.008
I12.0 Hypertensive renal disease with renal failure
0.000 0.991 0.009
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic
0.000 0.991 0.008
I01.9 Acute rheumatic heart disease, unspecified
0.000 0.991 0.008
I01.8 Other acute rheumatic heart disease
0.000 0.991 0.008
I01.2 Acute rheumatic myocarditis
0.000 0.991 0.008
I01.1 Acute rheumatic endocarditis
0.000 0.991 0.008
I01.0 Acute rheumatic pericarditis
0.000 0.991 0.008
I02.9 Rheumatic chorea without heart involvement
0.000 0.991 0.008
I02.0 Rheumatic chorea with heart involvement
0.000 0.991 0.008
I74 Arterial embolism and thrombosis
0.000 0.992 0.008
I73 Other peripheral vascular diseases
0.000 0.992 0.008
I63.1 Cerebral infarction due to embolism of precerebral arteries
0.000 0.992 0.008
I69.1 Sequelae of intracerebral haemorrhage
0.000 0.992 0.008
I05.0 Mitral stenosis
0.000 0.992 0.008
I61 Intracerebral haemorrhage
0.000 0.992 0.008
Z30.5 Surveillance of (intra-uterine) contraceptive device
0.000 0.992 0.008
I27.8 Other specified pulmonary heart diseases
0.000 0.992 0.008
I69.8 Sequelae of other and unspecified cerebrovascular diseases
0.000 0.992 0.008
I15.0 Renovascular hypertension
0.000 0.992 0.008
I11 Hypertensive heart disease
0.000 0.992 0.008
I67 Other cerebrovascular diseases
0.000 0.992 0.008
I15.8 Other secondary hypertension
0.000 0.992 0.008
I15.2 Hypertension secondary to endocrine disorders
0.000 0.992 0.008
I27.1 Kyphoscoliotic heart disease
0.000 0.992 0.008
I64 Stroke, not specified as haemorrhage or infarction
0.000 0.992 0.008
I62.9 Intracranial haemorrhage (nontraumatic), unspecified
0.000 0.992 0.008
I15.1 Hypertension secondary to other renal disorders
0.000 0.992 0.008
I72.3 Aneurysm of iliac artery
0.000 0.992 0.008
I62.1 Nontraumatic extradural haemorrhage
0.000 0.992 0.007
I63.8 Other cerebral infarction
0.000 0.992 0.007
I63.0 Cerebral infarction due to thrombosis of precerebral arteries
0.000 0.992 0.007
I70.1 Atherosclerosis of renal artery
0.000 0.993 0.007
I10 Essential (primary) hypertension
0.000 0.993 0.007
I60 Subarachnoid haemorrhage
0.000 0.993 0.007
I72.2 Aneurysm of renal artery
0.000 0.993 0.007
I13.1 Hypertensive heart and renal disease with renal failure
0.000 0.993 0.007
I13.0 Hypertensive heart and renal disease with (congestive) heart failure
0.000 0.993 0.007
I13.9 Hypertensive heart and renal disease, unspecified
0.000 0.993 0.007
I70.9 Generalised and unspecified atherosclerosis
0.000 0.993 0.007
I72.5 Aneurysm and dissection of other precerebral arteries
0.000 0.993 0.007
I70.8 Atherosclerosis of other arteries
0.000 0.993 0.007
I74.5 Embolism and thrombosis of iliac artery
0.000 0.993 0.007
I66.2 Occlusion and stenosis of posterior cerebral artery
0.000 0.993 0.007
I74.9 Embolism and thrombosis of unspecified artery
0.000 0.993 0.007
I68.8 Other cerebrovascular disorders in diseases classified elsewhere
0.000 0.993 0.007
I68.2 Cerebral arteritis in other diseases classified elsewhere
0.000 0.993 0.007
I68.1 Cerebral arteritis in infectious and parasitic diseases classified elsewhere
0.000 0.993 0.007
I68.0 Cerebral amyloid angiopathy
0.000 0.993 0.007
I63.3 Cerebral infarction due to thrombosis of cerebral arteries
0.000 0.993 0.007
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure
0.000 0.993 0.007
I72.1 Aneurysm of artery of upper extremity
0.000 0.993 0.007
J33.9 Nasal polyp, unspecified
0.007 0.993 0.000
I78.9 Disease of capillaries, unspecified
0.000 0.993 0.007
I12.9 Hypertensive renal disease without renal failure
0.000 0.993 0.007
I66.4 Occlusion and stenosis of multiple and bilateral cerebral arteries
0.000 0.993 0.007
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.000 0.993 0.007
I72.6 Aneurysm and dissection of vertebral artery
0.000 0.993 0.007
I70.0 Atherosclerosis of aorta
0.000 0.993 0.007
I79.1 Aortitis in diseases classified elsewhere
0.000 0.993 0.007
I79.0 Aneurysm of aorta in diseases classified elsewhere
0.000 0.993 0.007
I66.1 Occlusion and stenosis of anterior cerebral artery
0.000 0.993 0.007
I66.3 Occlusion and stenosis of cerebellar arteries
0.000 0.993 0.006
I27.2 Other secondary pulmonary hypertension
0.000 0.993 0.007
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.993 0.006
I61.3 Intracerebral haemorrhage in brain stem
0.000 0.993 0.007
I74.4 Embolism and thrombosis of arteries of extremities, unspecified
0.000 0.993 0.007
I61.1 Intracerebral haemorrhage in hemisphere, cortical
0.000 0.993 0.006
I66.8 Occlusion and stenosis of other cerebral artery
0.000 0.993 0.006
I66.0 Occlusion and stenosis of middle cerebral artery
0.000 0.993 0.006
I67.2 Cerebral atherosclerosis
0.000 0.993 0.007
I28.1 Aneurysm of pulmonary artery
0.000 0.993 0.006
I61.8 Other intracerebral haemorrhage
0.000 0.993 0.006
I74.1 Embolism and thrombosis of other and unspecified parts of aorta
0.000 0.993 0.006
I78.8 Other diseases of capillaries
0.000 0.993 0.006
I73.0 Raynaud's syndrome
0.000 0.993 0.006
I72.0 Aneurysm of carotid artery
0.000 0.994 0.006
N31 Neuromuscular dysfunction of bladder, not elsewhere classified
0.000 0.994 0.006
I27.9 Pulmonary heart disease, unspecified
0.000 0.994 0.006
I72.9 Aneurysm of unspecified site
0.000 0.994 0.006
I26 Pulmonary embolism
0.000 0.994 0.006
I61.2 Intracerebral haemorrhage in hemisphere, unspecified
0.000 0.994 0.006
I74.0 Embolism and thrombosis of abdominal aorta
0.000 0.994 0.006
I28.9 Disease of pulmonary vessels, unspecified
0.000 0.994 0.006
I28.0 Arteriovenous fistula of pulmonary vessels
0.000 0.994 0.006
I67.9 Cerebrovascular disease, unspecified
0.000 0.994 0.006
I78.0 Hereditary haemorrhagic telangiectasia
0.000 0.994 0.006
I66.9 Occlusion and stenosis of unspecified cerebral artery
0.000 0.994 0.006
I73.1 Thromboangiitis obliterans [Buerger]
0.000 0.994 0.006
I60.4 Subarachnoid haemorrhage from basilar artery
0.000 0.994 0.006
I60.1 Subarachnoid haemorrhage from middle cerebral artery
0.000 0.994 0.006
I67.6 Nonpyogenic thrombosis of intracranial venous system
0.000 0.994 0.006
I61.9 Intracerebral haemorrhage, unspecified
0.000 0.994 0.006
I28.8 Other specified diseases of pulmonary vessels
0.000 0.994 0.006
I67.5 Moyamoya disease
0.000 0.994 0.006
I67.3 Progressive vascular leukoencephalopathy
0.000 0.994 0.006
I73.8 Other specified peripheral vascular diseases
0.000 0.994 0.006
I63.9 Cerebral infarction, unspecified
0.000 0.994 0.006
I70.10 Atherosclerosis of renal artery (without gangrene)
0.000 0.994 0.006
I67.7 Cerebral arteritis, not elsewhere classified
0.000 0.994 0.006
I70.2 Atherosclerosis of arteries of the extremities
0.000 0.994 0.006
I79.2 Peripheral angiopathy in diseases classified elsewhere
0.000 0.994 0.006
I99 Other and unspecified disorders of circulatory system
0.000 0.994 0.006
I67.4 Hypertensive encephalopathy
0.000 0.994 0.006
I98 Other disorders of circulatory system in diseases classified elsewhere
0.000 0.994 0.006
I61.6 Intracerebral haemorrhage, multiple localised
0.000 0.994 0.006
I61.4 Intracerebral haemorrhage in cerebellum
0.000 0.994 0.006
I61.0 Intracerebral haemorrhage in hemisphere, subcortical
0.000 0.994 0.006
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.000 0.994 0.006
I67.0 Dissection of cerebral arteries, nonruptured
0.000 0.994 0.006
I60.3 Subarachnoid haemorrhage from posterior communicating artery
0.000 0.994 0.005
I60.8 Other subarachnoid haemorrhage
0.000 0.994 0.005
I72.8 Aneurysm of other specified arteries
0.000 0.994 0.005
I70.11 Atherosclerosis of renal artery (with gangrene)
0.000 0.994 0.005
I67.8 Other specified cerebrovascular diseases
0.000 0.994 0.006
I78.1 Naevus, nonneoplastic
0.000 0.994 0.005
I60.5 Subarachnoid haemorrhage from vertebral artery
0.000 0.994 0.005
I62.0 Subdural haemorrhage (acute) (nontraumatic)
0.000 0.994 0.005
I70.90 Generalized and unspecified atherosclerosis (without gangrene)
0.000 0.994 0.005
N31.2 Flaccid neuropathic bladder, not elsewhere classified
0.000 0.994 0.005
I11.9 Hypertensive heart disease without (congestive) heart failure
0.000 0.994 0.005
I74.8 Embolism and thrombosis of other arteries
0.000 0.994 0.005
I70.80 Atherosclerosis of other arteries (without gangrene)
0.000 0.995 0.005
I70.91 Generalized and unspecified atherosclerosis (with gangrene)
0.000 0.995 0.005
I61.5 Intracerebral haemorrhage, intraventricular
0.000 0.995 0.005
I70.81 Atherosclerosis of other arteries (with gangrene)
0.000 0.995 0.005
I07.1 Tricuspid insufficiency
0.001 0.995 0.005
I60.6 Subarachnoid haemorrhage from other intracranial arteries
0.000 0.995 0.005
I65.3 Occlusion and stenosis of multiple and bilateral precerebral arteries
0.000 0.995 0.005
I72.4 Aneurysm of artery of lower extremity
0.000 0.995 0.005
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation
0.000 0.995 0.005
I65.9 Occlusion and stenosis of unspecified precerebral artery
0.000 0.995 0.005
I70.01 Atherosclerosis of aorta (with gangrene)
0.000 0.995 0.005
I65.0 Occlusion and stenosis of vertebral artery
0.000 0.995 0.005
N31.0 Uninhibited neuropathic bladder, not elsewhere classified
0.000 0.995 0.005
I11.0 Hypertensive heart disease with (congestive) heart failure
0.000 0.995 0.005
I77 Other disorders of arteries and arterioles
0.001 0.995 0.005
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified
0.000 0.995 0.005
I65.1 Occlusion and stenosis of basilar artery
0.000 0.995 0.005
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.000 0.995 0.005
I65.8 Occlusion and stenosis of other precerebral artery
0.000 0.995 0.005
N31.1 Reflex neuropathic bladder, not elsewhere classified
0.000 0.995 0.005
I26.0 Pulmonary embolism with mention of acute cor pulmonale
0.000 0.995 0.005
I70.00 Atherosclerosis of aorta (without gangrene)
0.000 0.995 0.005
I73.9 Peripheral vascular disease, unspecified
0.000 0.995 0.005
I97.8 Other postprocedural disorders of circulatory system, not elsewhere classified
0.000 0.995 0.005
I98.3 Oesophageal varices with bleeding in diseases classified elsewhere
0.000 0.995 0.004
I60.9 Subarachnoid haemorrhage, unspecified
0.000 0.995 0.004
I98.8 Other specified disorders of circulatory system in diseases classified elsewhere
0.000 0.995 0.004
I98.1 Cardiovascular disorders in other infectious and parasitic diseases classified elsewhere
0.000 0.995 0.004
I98.0 Cardiovascular syphilis
0.000 0.995 0.004
I67.1 Cerebral aneurysm, nonruptured
0.000 0.996 0.004
I70.21 Atherosclerosis of arteries of extremities (with gangrene)
0.000 0.996 0.004
I95 Hypotension
0.000 0.996 0.004
I60.2 Subarachnoid haemorrhage from anterior communicating artery
0.000 0.996 0.004
J33 Nasal polyp
0.004 0.996 0.000
M23.22 Derangement of meniscus due to old tear or injury (Posterior cruciate ligament or Posterior horn of medial meniscus)
0.000 0.996 0.004
I97.9 Postprocedural disorder of circulatory system, unspecified
0.000 0.996 0.004
I97.0 Postcardiotomy syndrome
0.000 0.996 0.004
I97.2 Postmastectomy lymphoedema syndrome
0.000 0.996 0.004
I77.8 Other specified disorders of arteries and arterioles
0.000 0.996 0.004
I77.3 Arterial fibromuscular dysplasia
0.000 0.996 0.004
M13.90 Arthritis, unspecified (Multiple sites)
0.000 0.996 0.004
I77.5 Necrosis of artery
0.001 0.996 0.003
I77.4 Coeliac artery compression syndrome
0.001 0.996 0.003
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.000 0.996 0.004
I77.0 Arteriovenous fistula, acquired
0.000 0.996 0.003
J33.0 Polyp of nasal cavity
0.004 0.996 0.000
R00.1 Bradycardia, unspecified
0.000 0.996 0.004
J33.8 Other polyp of sinus
0.004 0.996 0.000
I97.1 Other functional disturbances following cardiac surgery
0.000 0.996 0.003
N81 Female genital prolapse
0.004 0.996 0.000
I98.2 Oesophageal varices in diseases classified elsewhere
0.000 0.996 0.003
N81.6 Rectocele
0.004 0.996 0.000
I77.2 Rupture of artery
0.001 0.996 0.003
I70.20 Atherosclerosis of arteries of extremities (without gangrene)
0.000 0.996 0.003
I95.0 Idiopathic hypotension
0.000 0.996 0.003
N81.8 Other female genital prolapse
0.003 0.996 0.000
N81.5 Vaginal enterocele
0.003 0.997 0.000
D23.1 Skin of eyelid, including canthus
0.000 0.997 0.003
I77.6 Arteritis, unspecified
0.000 0.997 0.003
I95.8 Other hypotension
0.000 0.997 0.003
I95.1 Orthostatic hypotension
0.000 0.997 0.003
I95.2 Hypotension due to drugs
0.000 0.997 0.003
J33.1 Polypoid sinus degeneration
0.003 0.997 0.000
K60.2 Anal fissure, unspecified
0.000 0.997 0.003
I77.9 Disorder of arteries and arterioles, unspecified
0.001 0.997 0.003
N81.9 Female genital prolapse, unspecified
0.003 0.997 0.000
I65.2 Occlusion and stenosis of carotid artery
0.000 0.997 0.003
C34.9 Bronchus or lung, unspecified
0.003 0.997 0.000
H83.0 Labyrinthitis
0.003 0.997 0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.000 0.997 0.003
N81.0 Female urethrocele
0.003 0.997 0.000
M65.34 Trigger finger-Hand
0.000 0.997 0.003
Z45.0 Adjustment and management of cardiac pacemaker
0.000 0.997 0.003
M72.04 Palmar fascial fibromatosis [Dupuytren]-Hand
0.000 0.998 0.002
N72 Inflammatory disease of cervix uteri
0.000 0.998 0.002
H83 Other diseases of inner ear
0.002 0.998 0.000
D25.1 Intramural leiomyoma of uterus
0.000 0.998 0.002
K29.1 Other acute gastritis
0.000 0.998 0.002
N31.8 Other neuromuscular dysfunction of bladder
0.000 0.998 0.002
D46.9 Myelodysplastic syndrome, unspecified
0.000 0.998 0.002
M65.3 Trigger finger
0.000 0.998 0.002
C34 Malignant neoplasm of bronchus and lung
0.002 0.998 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.000 0.998 0.002
I77.1 Stricture of artery
0.001 0.998 0.001
M65.94 Synovitis and tenosynovitis, unspecified (Hand)
0.000 0.998 0.002
C34.3 Lower lobe, bronchus or lung
0.002 0.998 0.000
H93.1 Tinnitus
0.002 0.998 0.000
N81.4 Uterovaginal prolapse, unspecified
0.002 0.998 0.000
M65.96 Synovitis and tenosynovitis, unspecified (Lower leg)
0.000 0.998 0.002
H83.9 Disease of inner ear, unspecified
0.002 0.998 0.000
H83.8 Other specified diseases of inner ear
0.002 0.998 0.000
H83.3 Noise effects on inner ear
0.002 0.998 0.000
H83.1 Labyrinthine fistula
0.002 0.998 0.000
K52.8 Other specified non-infective gastro-enteritis and colitis
0.002 0.998 0.000
M65.9 Synovitis and tenosynovitis, unspecified
0.000 0.998 0.002
H83.2 Labyrinthine dysfunction
0.002 0.998 0.000
Z95.0 Presence of cardiac pacemaker
0.000 0.998 0.002
K91.8 Other postprocedural disorders of digestive system, not elsewhere classified
0.000 0.998 0.002
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants
0.000 0.998 0.002
T42.4 Benzodiazepines
0.000 0.998 0.002
M65.97 Synovitis and tenosynovitis, unspecified (Ankle and foot)
0.000 0.998 0.002
T50.9 Other and unspecified drugs, medicaments and biological substances
0.000 0.998 0.002
S32.40 Fracture of acetabulum (closed)
0.000 0.998 0.002
T42.1 Iminostilbenes
0.000 0.998 0.002
M65 Synovitis and tenosynovitis
0.000 0.998 0.002
M65.38 Trigger finger-Other
0.000 0.998 0.002
M65.37 Trigger finger-Ankle/foot
0.000 0.998 0.002
M65.36 Trigger finger-Lower leg
0.000 0.998 0.002
M65.35 Trigger finger-Pelvic/thigh
0.000 0.998 0.002
M65.33 Trigger finger-Forearm
0.000 0.998 0.002
M65.32 Trigger finger-Upper arm
0.000 0.998 0.002
M65.31 Trigger finger-Shldr region
0.000 0.998 0.002
M65.30 Trigger finger-Mult sites
0.000 0.998 0.002
K83.1 Obstruction of bile duct
0.002 0.998 0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified
0.000 0.998 0.002
R19.5 Other fecal abnormalities
0.000 0.998 0.002
T42.5 Mixed antiepileptics, not elsewhere classified
0.000 0.998 0.002
T42.2 Succinimides and oxazolidinediones
0.000 0.998 0.002
C34.1 Upper lobe, bronchus or lung
0.002 0.998 0.000
M65.39 Trigger finger-Site unspec
0.000 0.998 0.002
M65.90 Synovitis and tenosynovitis, unspecified (Multiple sites)
0.000 0.998 0.002
C34.2 Middle lobe, bronchus or lung
0.002 0.998 0.000
C34.0 Main bronchus
0.002 0.998 0.000
L03.2 Cellulitis of face
0.002 0.998 0.000
T42.3 Barbiturates
0.000 0.998 0.002
M23.23 Derangement of meniscus due to old tear or injury (Medial collateral ligament or Other and unspecified medial meniscus)
0.000 0.998 0.002
T42.0 Hydantoin derivatives
0.000 0.998 0.002
N81.3 Complete uterovaginal prolapse
0.001 0.998 0.001
C34.8 Overlapping lesion of bronchus and lung
0.001 0.998 0.000
M65.98 Synovitis and tenosynovitis, unspecified (Other)
0.000 0.998 0.002
S22.00 Fracture of thoracic vertebra (closed)
0.000 0.998 0.002
O72.1 Other immediate postpartum haemorrhage
0.002 0.998 0.000
K13.0 Diseases of lips
0.000 0.998 0.002
M65.1 Other infective (teno)synovitis
0.000 0.998 0.002
H80-H83 Diseases of inner ear
0.002 0.998 0.000
M65.99 Synovitis and tenosynovitis, unspecified (Site unspecified)
0.000 0.998 0.001
C92.1 Chronic myeloid leukaemia
0.002 0.998 0.000
H80 Otosclerosis
0.002 0.998 0.000
R00 Abnormalities of heart beat
0.000 0.998 0.002
M65.2 Calcific tendinitis
0.000 0.998 0.001
H81 Disorders of vestibular function
0.002 0.998 0.000
M77.12 Lateral epicondylitis (Upper arm)
0.000 0.998 0.002
K65.0 Acute peritonitis
0.002 0.998 0.000
M65.8 Other synovitis and tenosynovitis
0.000 0.998 0.001
M23.24 Derangement of meniscus due to old tear or injury (Lateral collateral ligament or Anterior horn of lateral meniscus)
0.000 0.998 0.002
K83.8 Other specified diseases of biliary tract
0.002 0.998 0.000
M65.0 Abscess of tendon sheath
0.000 0.998 0.001
Z57.5 Occupational exposure to toxic agents in other industries
0.000 0.998 0.002
M65.95 Synovitis and tenosynovitis, unspecified (Pelvic region and thigh)
0.000 0.998 0.001
H80.9 Otosclerosis, unspecified
0.001 0.998 0.000
M65.4 Radial styloid tenosynovitis [de Quervain]
0.000 0.998 0.001
N28.8 Other specified disorders of kidney and ureter
0.002 0.998 0.000
M67.2 Synovial hypertrophy, not elsewhere classified
0.000 0.998 0.001
M65.14 Other infective (teno)synovitis (Hand)
0.000 0.998 0.001
M65.92 Synovitis and tenosynovitis, unspecified (Upper arm)
0.000 0.998 0.001
L02.3 Cutaneous abscess, furuncle and carbuncle of buttock
0.001 0.998 0.000
E87.5 Hyperkalaemia
0.000 0.999 0.001
H81.9 Disorder of vestibular function, unspecified
0.001 0.999 0.000
R25.1 Tremor, unspecified
0.001 0.999 0.000
M65.44 Radial styloid tenosynovitis [de Quervain] (Hand)
0.000 0.999 0.001
H80.0 Otosclerosis involving oval window, nonobliterative
0.001 0.999 0.000
H81.3 Other peripheral vertigo
0.001 0.999 0.000
K60.1 Chronic anal fissure
0.000 0.999 0.001

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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