TreeWAS – Variant ID: rs4811340

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
I10 Essential (primary) hypertension	0.000	0.638	0.362
Y44.2 Anticoagulants	0.057	0.943	0.000
Y44 Agents primarily affecting blood constituents	0.052	0.948	0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.049	0.951	0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.048	0.952	0.000
Y51 Drugs primarily affecting the autonomic nervous system	0.047	0.953	0.000
Y42.8 Other and unspecified hormones and their synthetic substitutes	0.045	0.955	0.000
Y51.7 Beta-Adrenoreceptor antagonists, not elsewhere classified	0.044	0.956	0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs	0.044	0.956	0.000
Y42.5 Other oestrogens and progestogens	0.043	0.957	0.000
Y44.5 Thrombolytic drugs	0.042	0.958	0.000
Y49 Psychotropic drugs, not elsewhere classified	0.042	0.958	0.000
Y42.0 Glucocorticoids and synthetic analogs	0.041	0.959	0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs	0.041	0.959	0.000
Y42.1 Thyroid hormones and substitutes	0.040	0.960	0.000
Y45.2 Propionic acid derivatives	0.040	0.960	0.000
Y45.0 Opioids and related analgesics	0.040	0.960	0.000
Y48 Anaesthetics and therapeutic gases	0.039	0.961	0.000
Y51.6 @-Adrenoreceptor antagonists, not elsewhere classified	0.038	0.962	0.000
Y42.2 Antithyroid drugs	0.038	0.962	0.000
Y44.3 Anticoagulant antagonists, vitamin K and other coagulants	0.038	0.962	0.000
Y42.6 Antigonadotrophins, antioestrogens, antiandrogens, not elsewhere classified	0.037	0.962	0.000
Y44.9 Other and unspecified agents affecting blood constituents	0.037	0.963	0.000
Y44.7 Plasma substitutes	0.037	0.963	0.000
Y44.6 Natural blood and blood products	0.037	0.963	0.000
Y44.1 Vitamin B12, folic acid and other anti-megaloblastic-anaemia preparations	0.037	0.963	0.000
Y45.1 Salicylates	0.036	0.964	0.000
Y51.3 Other parasympatholytics [anticholinergics and antimuscarinics] and spasmolytics, not elsewhere classified	0.036	0.964	0.000
Y49.2 Other and unspecified antidepressants	0.035	0.965	0.000
Y44.4 Antithrombotic drugs [platelet-aggregation inhibitors]	0.035	0.965	0.000
Y51.9 Other and unspecified drugs primarily affecting the autonomic nervous system	0.035	0.965	0.000
Y42.4 Oral contraceptives	0.035	0.965	0.000
Y58 Bacterial vaccines	0.035	0.965	0.000
Y51.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.035	0.965	0.000
Y50 Central nervous system stimulants, not elsewhere classified	0.035	0.965	0.000
Y48.4 Anaesthetic, unspecified	0.034	0.966	0.000
Y44.0 Iron preparations and other anti-hypochromic-anaemia preparations	0.034	0.966	0.000
Y49.5 Other antipsychotics and neuroleptics	0.034	0.966	0.000
Y51.8 Centrally acting and adrenergic-neuron-blocking agents, not elsewhere classified	0.034	0.966	0.000
Y51.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.034	0.966	0.000
Y51.2 Ganglionic blocking drugs, not elsewhere classified	0.034	0.966	0.000
Y51.1 Other parasympathomimetics [cholinergics]	0.034	0.966	0.000
Y51.0 Anticholinesterase agents	0.034	0.966	0.000
Y59 Other and unspecified vaccines and biological substances	0.033	0.966	0.000
Y52 Agents primarily affecting the cardiovascular system	0.033	0.967	0.000
I10-I15 Hypertensive diseases	0.000	0.967	0.033
Y42.9 Other and unspecified hormone antagonists	0.032	0.967	0.000
Y42.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.032	0.968	0.000
Y56.3 Emollients, demulcents and protectants	0.032	0.968	0.000
Y45.4 Antirheumatics	0.032	0.968	0.000
Y56.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.032	0.968	0.000
Y49.3 Phenothiazine antipsychotics and neuroleptics	0.031	0.968	0.000
Y56.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.031	0.969	0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system	0.031	0.969	0.000
Y49.0 Tricyclic and tetracyclic antidepressants	0.031	0.969	0.000
Y46 Antiepileptics and anti-Parkinsonism drugs	0.031	0.969	0.000
Y49.9 Psychotropic drug, unspecified	0.030	0.969	0.000
Y49.8 Other psychotropic drugs, not elsewhere classified	0.030	0.969	0.000
Y49.7 Psychostimulants with abuse potential	0.030	0.969	0.000
Y49.6 Psychodysleptics [hallucinogens]	0.030	0.969	0.000
Y49.4 Butyrophenone and thioxanthene neuroleptics	0.030	0.969	0.000
Y49.1 Monoamine-oxidase-inhibitor antidepressants	0.030	0.969	0.000
Y45.5 4-Aminophenol derivatives	0.030	0.970	0.000
Y53 Agents primarily affecting the gastro-intestinal system	0.029	0.970	0.000
Y56.9 Topical agent, unspecified	0.029	0.971	0.000
Y56.8 Other topical agents	0.029	0.971	0.000
Y56.7 Dental drugs, topically applied	0.029	0.971	0.000
Y56.6 Otorhinolaryngological drugs and preparations	0.029	0.971	0.000
Y56.5 Ophthalmological drugs and preparations	0.029	0.971	0.000
Y56.2 Local astringents and local detergents	0.029	0.971	0.000
Y56.1 Antipruritics	0.029	0.971	0.000
Y52.9 Other and unspecified agents primarily affecting the cardiovascular system	0.029	0.971	0.000
Y42.7 Androgens and anabolic congeners	0.028	0.972	0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.028	0.972	0.000
Y52.5 Other antihypertensive drugs, not elsewhere classified	0.028	0.972	0.000
Y48.5 Therapeutic gases	0.028	0.972	0.000
Y48.1 Parenteral anaesthetics	0.028	0.972	0.000
Y48.0 Inhaled anaesthetics	0.028	0.972	0.000
Y52.3 Coronary vasodilators, not elsewhere classified	0.028	0.972	0.000
Y48.3 Local anaesthetics	0.028	0.972	0.000
Y52.0 Cardiac-stimulant glycosides and drugs of similar action	0.027	0.973	0.000
Y47 Sedatives, hypnotics and antianxiety drugs	0.026	0.974	0.000
Y58.0 BCG vaccine	0.026	0.974	0.000
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.026	0.974	0.000
Y45.9 Analgesic, antipyretic and anti-inflammatory drug, unspecified	0.025	0.974	0.000
Y58.9 Other and unspecified bacterial vaccines	0.025	0.974	0.000
Y58.8 Mixed bacterial vaccines, except combinations with a pertussis component	0.025	0.974	0.000
Y58.6 Pertussis vaccine, including combinations with a pertussis component	0.025	0.974	0.000
Y58.5 Diphtheria vaccine	0.025	0.974	0.000
Y58.4 Tetanus vaccine	0.025	0.974	0.000
Y58.3 Plague vaccine	0.025	0.974	0.000
Y58.2 Cholera vaccine	0.025	0.974	0.000
Y58.1 Typhoid and paratyphoid vaccine	0.025	0.974	0.000
Y50.9 Central nervous system stimulant, unspecified	0.025	0.975	0.000
Y50.8 Other central nervous system stimulants	0.025	0.975	0.000
Y50.2 Methylxanthines, not elsewhere classified	0.025	0.975	0.000
Y50.1 Opioid receptor antagonists	0.025	0.975	0.000
Y50.0 Analeptics	0.025	0.975	0.000
Y41 Other systemic anti-infectives and antiparasitics	0.025	0.975	0.000
Y46.7 Anti-Parkinsonism drugs	0.024	0.975	0.000
Y43 Primarily systemic agents	0.025	0.975	0.000
Y59.9 Vaccine or biological substance, unspecified	0.024	0.976	0.000
Y59.8 Other specified vaccines and biological substances	0.024	0.976	0.000
Y59.2 Protozoal vaccines	0.024	0.976	0.000
Y59.1 Rickettsial vaccines	0.024	0.976	0.000
Y59.0 Viral vaccines	0.024	0.976	0.000
Y52.8 Antivaricose drugs, including sclerosing agents	0.024	0.976	0.000
I13 Hypertensive heart and renal disease	0.000	0.976	0.024
Y57 Other and unspecified drugs and medicaments	0.024	0.976	0.000
Y53.1 Other antacids and anti-gastric-secretion drugs	0.023	0.977	0.000
Y48.2 Other and unspecified general anaesthetics	0.023	0.977	0.000
Y59.3 Immunoglobulin	0.023	0.977	0.000
Y53.2 Stimulant laxatives	0.023	0.977	0.000
Y43.1 Antineoplastic antimetabolites	0.023	0.977	0.000
Y54.3 Benzothiadiazine derivatives	0.023	0.977	0.000
Y55.7 Other and unspecified agents primarily acting on the respiratory system	0.022	0.977	0.000
Y55.5 Anticommon cold drugs	0.022	0.977	0.000
Y55.3 Antitussives	0.022	0.977	0.000
Y55.2 Other and unspecified agents primarily acting on muscles	0.022	0.977	0.000
Y55.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.022	0.977	0.000
Y55.0 Oxytocic drugs	0.022	0.977	0.000
M65.34 Trigger finger-Hand	0.023	0.977	0.000
Y40.0 Penicillins	0.023	0.977	0.000
Y54.4 Loop [high-ceiling] diuretics	0.022	0.977	0.000
Y40 Systemic antibiotics	0.022	0.978	0.000
Y52.7 Peripheral vasodilators	0.022	0.978	0.000
Y46.8 Antispasticity drugs	0.022	0.978	0.000
Y46.5 Valproic acid	0.022	0.978	0.000
Y46.3 Deoxybarbiturates	0.022	0.978	0.000
Y46.1 Oxazolidinediones	0.022	0.978	0.000
Y46.0 Succinimides	0.022	0.978	0.000
Y55.6 Antiasthmatics, not elsewhere classified	0.022	0.978	0.000
Y46.2 Hydantoin derivatives	0.022	0.978	0.000
Y54.7 Agents affecting calcification	0.021	0.978	0.000
Y53.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.021	0.978	0.000
Y53.7 Emetics	0.021	0.978	0.000
Y53.6 Antidiarrhoeal drugs	0.021	0.978	0.000
Y53.5 Digestants	0.021	0.978	0.000
Y53.3 Saline and osmotic laxatives	0.021	0.978	0.000
Y53.0 Histamine H2-receptor antagonists	0.021	0.978	0.000
Y45.8 Other analgesics and antipyretics	0.021	0.979	0.000
I11 Hypertensive heart disease	0.000	0.979	0.021
Y46.6 Other and unspecified antiepileptics	0.020	0.979	0.000
Y54.9 Mineral salts, not elsewhere classified	0.020	0.979	0.000
Y54.6 Electrolytic, caloric and water-balance agents	0.020	0.979	0.000
Y54.2 Carbonic-anhydrase inhibitors	0.020	0.979	0.000
Y54.0 Mineralocorticoids	0.020	0.979	0.000
Y55.4 Expectorants	0.020	0.980	0.000
Y52.1 Calcium-channel blockers	0.020	0.980	0.000
Y57.6 Other diagnostic agents	0.020	0.980	0.000
Y41.0 Sulphonamides	0.019	0.981	0.000
Y53.8 Other agents primarily affecting the gastro-intestinal system	0.019	0.981	0.000
Y47.9 Sedative, hypnotic and antianxiety drug, unspecified	0.019	0.981	0.001
Y47.8 Other sedatives, hypnotics and antianxiety drugs	0.019	0.981	0.001
Y47.5 Mixed sedatives and hypnotics, not elsewhere classified	0.019	0.981	0.001
Y47.4 Bromine compounds	0.019	0.981	0.001
Y47.3 Paraldehyde	0.019	0.981	0.001
Y47.2 Chloral derivatives	0.019	0.981	0.001
Y47.0 Barbiturates, not elsewhere classified	0.019	0.981	0.001
Y54.8 Agents affecting uric acid metabolism	0.019	0.981	0.000
Y41.9 Systemic anti-infective and antiparasitic, unspecified	0.018	0.982	0.000
Y41.4 Anthelminthics	0.018	0.982	0.000
Y41.3 Other antiprotozoal drugs	0.018	0.982	0.000
Y41.2 Antimalarials and drugs acting on other blood protozoa	0.018	0.982	0.000
Y41.1 Antimycobacterial drugs	0.018	0.982	0.000
Y43.9 Primarily systemic agent, unspecified	0.018	0.982	0.000
Y43.8 Other primarily systemic agents, not elsewhere classified	0.018	0.982	0.000
Y43.6 Enzymes, not elsewhere classified	0.018	0.982	0.000
Y43.5 Acidifying and alkalising agents	0.018	0.982	0.000
Y43.2 Antineoplastic natural products	0.018	0.982	0.000
Y52.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.017	0.983	0.000
I13.9 Hypertensive heart and renal disease, unspecified	0.000	0.983	0.017
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure	0.000	0.983	0.017
I13.1 Hypertensive heart and renal disease with renal failure	0.000	0.983	0.017
I13.0 Hypertensive heart and renal disease with (congestive) heart failure	0.000	0.983	0.017
Y57.7 Vitamins, not elsewhere classified	0.017	0.983	0.000
Y57.4 Pharmaceutical excipients	0.017	0.983	0.000
Y57.3 Alcohol deterrents	0.017	0.983	0.000
Y57.2 Antidotes and chelating agents, not elsewhere classified	0.017	0.983	0.000
Y57.1 Lipotropic drugs	0.017	0.983	0.000
Y57.0 Appetite depressants [anorectics]	0.017	0.983	0.000
Y40.6 Rifamycins	0.017	0.983	0.000
Y46.4 Iminostilbenes	0.017	0.983	0.000
Y57.8 Other drugs and medicaments	0.017	0.983	0.000
Y40.4 Tetracyclines	0.016	0.984	0.000
Y40.2 Chloramphenicol group	0.016	0.984	0.000
I11.0 Hypertensive heart disease with (congestive) heart failure	0.000	0.984	0.016
Y43.0 Antiallergic and antiemetic drugs	0.015	0.984	0.000
Y41.5 Antiviral drugs	0.015	0.985	0.000
Y40.7 Antifungal antibiotics, systemically used	0.015	0.985	0.000
Y54.1 Mineralocorticoid antagonists [aldosterone antagonists]	0.014	0.985	0.000
M25.47 Effusion of joint (Ankle and foot)	0.000	0.986	0.014
Y52.2 Other antidysrhythmic drugs, not elsewhere classified	0.014	0.986	0.000
Y54.5 Other diuretics	0.014	0.986	0.000
K08.8 Other specified disorders of teeth and supporting structures	0.000	0.987	0.013
Y40.1 Cefalosporins and other -lactam antibiotics	0.013	0.987	0.000
Y53.4 Other laxatives	0.013	0.987	0.001
M19.09 Primary arthrosis of other joints (Site unspecified)	0.000	0.987	0.013
I11.9 Hypertensive heart disease without (congestive) heart failure	0.000	0.987	0.012
Y52.4 Angiotensin-converting-enzyme inhibitors	0.012	0.988	0.000
T83.8 Other complications of genito-urinary prosthetic devices, implants and grafts	0.012	0.988	0.000
M65.3 Trigger finger	0.012	0.988	0.000
Y40.5 Aminoglycosides	0.012	0.988	0.000
Y40.3 Macrolides	0.011	0.989	0.000
I12 Hypertensive renal disease	0.000	0.989	0.011
N31.9 Neuromuscular dysfunction of bladder, unspecified	0.000	0.989	0.011
Y43.4 Immunosuppressive agents	0.011	0.989	0.000
Y47.1 Benzodiazepines	0.010	0.989	0.001
I15 Secondary hypertension	0.001	0.989	0.010
Y40.9 Systemic antibiotic, unspecified	0.010	0.990	0.000
Y41.8 Other specified systemic anti-infectives and antiparasitics	0.010	0.990	0.000
N31 Neuromuscular dysfunction of bladder, not elsewhere classified	0.000	0.990	0.010
Y57.5 X-ray contrast media	0.010	0.990	0.000
Y40.8 Other systemic antibiotics	0.010	0.990	0.000
Y57.9 Drug or medicament, unspecified	0.009	0.991	0.000
N36.8 Other specified disorders of urethra	0.000	0.991	0.009
M65.39 Trigger finger-Site unspec	0.009	0.991	0.000
N31.8 Other neuromuscular dysfunction of bladder	0.000	0.991	0.009
N31.2 Flaccid neuropathic bladder, not elsewhere classified	0.000	0.991	0.009
M65.38 Trigger finger-Other	0.009	0.991	0.000
M65.37 Trigger finger-Ankle/foot	0.009	0.991	0.000
M65.36 Trigger finger-Lower leg	0.009	0.991	0.000
M65.35 Trigger finger-Pelvic/thigh	0.009	0.991	0.000
M65.33 Trigger finger-Forearm	0.009	0.991	0.000
M65.32 Trigger finger-Upper arm	0.009	0.991	0.000
M65.31 Trigger finger-Shldr region	0.009	0.991	0.000
M65.30 Trigger finger-Mult sites	0.009	0.991	0.000
N36 Other disorders of urethra	0.000	0.991	0.009
N36.9 Urethral disorder, unspecified	0.000	0.991	0.009
N36.1 Urethral diverticulum	0.000	0.992	0.008
R35 Polyuria	0.000	0.992	0.008
S42.00 Fracture of clavicle (closed)	0.008	0.992	0.000
I15.8 Other secondary hypertension	0.001	0.992	0.007
I15.0 Renovascular hypertension	0.001	0.992	0.007
N31.0 Uninhibited neuropathic bladder, not elsewhere classified	0.000	0.992	0.007
E14.9 Without complications	0.000	0.993	0.007
N31.1 Reflex neuropathic bladder, not elsewhere classified	0.000	0.993	0.007
M19.98 Arthrosis, unspecified (Other)	0.000	0.993	0.007
I15.2 Hypertension secondary to endocrine disorders	0.001	0.993	0.006
N36.0 Urethral fistula	0.000	0.993	0.007
M19.07 Primary arthrosis of other joints (Ankle and foot)	0.000	0.993	0.007
C15.5 Lower third of oesophagus	0.007	0.993	0.000
M25.4 Effusion of joint	0.000	0.994	0.006
O47.9 False labour, unspecified	0.006	0.994	0.000
M19.0 Primary arthrosis of other joints	0.000	0.994	0.006
I12.0 Hypertensive renal disease with renal failure	0.000	0.994	0.006
O47.1 False labour at or after 37 completed weeks of gestation	0.006	0.994	0.000
M25.40 Effusion of joint (Multiple sites)	0.000	0.994	0.006
S82.30 Fracture of lower end of tibia (closed)	0.006	0.994	0.000
N36.2 Urethral caruncle	0.000	0.994	0.005
I15.9 Seconday hypertension, unspecified	0.001	0.995	0.004
Z36.9 Antenatal screening, unspecified	0.005	0.995	0.000
E14 Unspecified diabetes mellitus	0.000	0.995	0.005
M25.41 Effusion of joint (Shoulder region)	0.000	0.995	0.005
I15.1 Hypertension secondary to other renal disorders	0.001	0.995	0.005
Y43.3 Other antineoplastic drugs	0.005	0.995	0.000
N36.3 Prolapsed urethral mucosa	0.000	0.995	0.005
M19.06 Primary arthrosis of other joints-Lower leg	0.000	0.995	0.005
O47 False labour	0.005	0.995	0.000
Z36.3 Antenatal screening for malformations using ultrasound and other physical methods	0.005	0.995	0.000
Z36 Antenatal screening	0.005	0.995	0.000
Z36.0 Antenatal screening for chromosomal anomalies	0.005	0.995	0.000
M25.44 Effusion of joint (Hand)	0.000	0.995	0.005
M25.49 Effusion of joint (Site unspecified)	0.000	0.995	0.005
M25.48 Effusion of joint (Other)	0.000	0.995	0.005
M25.42 Effusion of joint (Upper arm)	0.000	0.995	0.005
C34.1 Upper lobe, bronchus or lung	0.000	0.995	0.005
E14.6 With other specified complications	0.000	0.995	0.005
E14.3 With ophthalmic complications	0.000	0.995	0.005
N34.2 Other urethritis	0.000	0.995	0.005
M19.90 Arthrosis, unspecified (Multiple sites)	0.000	0.995	0.005
C15 Malignant neoplasm of oesophagus	0.005	0.995	0.000
N34 Urethritis and urethral syndrome	0.000	0.995	0.005
M19.05 Primary arthrosis of other joints (Pelvic region and thigh)	0.000	0.995	0.004
K14.9 Disease of tongue, unspecified	0.005	0.995	0.000
M19.03 Primary arthrosis of other joints (Forearm)	0.000	0.995	0.005
N30-N39 Other diseases of urinary system	0.000	0.995	0.005
S32.40 Fracture of acetabulum (closed)	0.005	0.995	0.000
M19.08 Primary arthrosis of other joints (Other)	0.000	0.995	0.004
Z36.1 Antenatal screening for raised alphafetoprotein level	0.004	0.996	0.000
M84.12 Nonunion of fracture [pseudarthrosis] (Upper arm)	0.004	0.996	0.000
C15.0 Cervical part of oesophagus	0.004	0.996	0.000
Z36.8 Other antenatal screening	0.004	0.996	0.000
C15.3 Upper third of oesophagus	0.004	0.996	0.000
M25.43 Effusion of joint (Forearm)	0.000	0.996	0.004
E27.1 Primary adrenocortical insufficiency	0.000	0.996	0.004
M25.45 Effusion of joint (Pelvic region and thigh)	0.000	0.996	0.004
E14.4 With neurological complications	0.000	0.996	0.004
E14.1 With ketoacidosis	0.000	0.996	0.004
M46.92 Inflammatory spondylopathy, unspecified (Cervical region)	0.004	0.996	0.000
E14.5 With peripheral circulatory complications	0.000	0.996	0.004
C15.9 Oesophagus, unspecified	0.004	0.996	0.000
E14.8 With unspecified complications	0.000	0.996	0.004
E14.7 With multiple complications	0.000	0.996	0.004
E14.0 With coma	0.000	0.996	0.004
Z36.2 Other antenatal screening based on amniocentesis	0.004	0.996	0.000
E14.2 Withrenal complications	0.000	0.996	0.004
Z36.5 Antenatal screening for isoimmunisation	0.004	0.996	0.000
M25.46 Effusion of joint (Lower leg)	0.000	0.996	0.004
O47.0 False labour before 37 completed weeks of gestation	0.004	0.996	0.000
N34.1 Nonspecific urethritis	0.000	0.996	0.004
Z29.2 Other prophylactic chemotherapy	0.000	0.996	0.004
H52.1 Myopia	0.000	0.996	0.004
Z43.1 Attention to gastrostomy	0.004	0.996	0.000
H11.4 Other conjunctival vascular disorders and cysts	0.004	0.996	0.000
N34.0 Urethral abscess	0.000	0.996	0.004
S42.0 Fracture of clavicle	0.004	0.996	0.000
M65 Synovitis and tenosynovitis	0.004	0.996	0.000
C15.8 Overlapping lesion of oesophagus	0.003	0.996	0.000
C15.2 Abdominal part of oesophagus	0.003	0.996	0.000
I70.20 Atherosclerosis of arteries of extremities (without gangrene)	0.004	0.996	0.000
K14.8 Other diseases of tongue	0.004	0.996	0.000
N48.1 Balanoposthitis	0.000	0.996	0.004
N37 Urethral disorders in diseases classified elsewhere	0.000	0.996	0.003
N33 Bladder disorders in diseases classified elsewhere	0.000	0.996	0.003
S52.10 Fracture of upper end of radius (closed)	0.000	0.996	0.004
M84.18 Nonunion of fracture [pseudarthrosis] (Other)	0.003	0.996	0.000
C15.1 Thoracic part of oesophagus	0.003	0.997	0.000
M19.00 Primary arthrosis of other joints (Multiple sites)	0.000	0.997	0.003
N34.3 Urethral syndrome, unspecified	0.000	0.997	0.003
M19.04 Primary arthrosis of other joints (Hand)	0.000	0.997	0.003
M84.1 Nonunion of fracture [pseudarthrosis]	0.003	0.997	0.000
M65.86 Other synovitis and tenosynovitis (Lower leg)	0.003	0.997	0.000
M19.01 Primary arthrosis of other joints (Shoulder region)	0.000	0.997	0.003
S27.00 Traumatic pneumothorax (without open wound into thoracic cavity)	0.003	0.997	0.000
W08.0 Home	0.000	0.997	0.003
M66.46 Spontaneous rupture of other tendons (Lower leg)	0.003	0.997	0.000
H11.9 Disorder of conjunctiva, unspecified	0.003	0.997	0.000
M65.1 Other infective (teno)synovitis	0.003	0.997	0.000
E27.3 Drug-induced adrenocortical insufficiency	0.000	0.997	0.003
E27.2 Addisonian crisis	0.000	0.997	0.003
Q18.1 Preauricular sinus and cyst	0.003	0.997	0.000
E27 Other disorders of adrenal gland	0.000	0.997	0.003
R25.2 Cramp and spasm	0.000	0.997	0.003
M65.8 Other synovitis and tenosynovitis	0.003	0.997	0.000
M84.17 Nonunion of fracture [pseudarthrosis] (Ankle and foot)	0.003	0.997	0.000
S42.01 Fracture of clavicle (open)	0.003	0.997	0.000
M65.0 Abscess of tendon sheath	0.003	0.997	0.000
D73.0 Hyposplenism	0.000	0.997	0.003
N33.8 Bladder disorders in other diseases classified elsewhere	0.000	0.997	0.003
N33.0 Tuberculous cystitis	0.000	0.997	0.003
N37.8 Other urethral disorders in diseases classified elsewhere	0.000	0.997	0.003
N37.0 Urethritis in diseases classified elsewhere	0.000	0.997	0.003
M19.02 Primary arthrosis of other joints (Upper arm)	0.000	0.997	0.002
M65.4 Radial styloid tenosynovitis [de Quervain]	0.003	0.997	0.000
M65.2 Calcific tendinitis	0.003	0.997	0.000
R79.9 Abnormal finding of blood chemistry, unspecified	0.000	0.997	0.003
H26.8 Other specified cataract	0.003	0.997	0.000
M84.11 Nonunion of fracture [pseudarthrosis] (Shoulder region)	0.003	0.997	0.000
K14 Diseases of tongue	0.003	0.997	0.000
M54.36 Sciatica (Lumbar region)	0.003	0.997	0.000
A49.9 Bacterial infection, unspecified	0.000	0.997	0.003
M84.19 Nonunion of fracture [pseudarthrosis] (Site unspecified)	0.003	0.997	0.000
M84.15 Nonunion of fracture [pseudarthrosis] (Pelvic region and thigh)	0.003	0.997	0.000
M84.10 Nonunion of fracture [pseudarthrosis] (Multiple sites)	0.003	0.997	0.000
I12.9 Hypertensive renal disease without renal failure	0.001	0.997	0.002
M65.14 Other infective (teno)synovitis (Hand)	0.002	0.997	0.000
N30.9 Cystitis, unspecified	0.000	0.997	0.003
Z36.4 Antenatal screening for foetal growth retardation using ultrasound and other physical methods	0.002	0.997	0.000
S27.0 Traumatic pneumothorax	0.003	0.997	0.000
M88.99 Paget's disease of bone, unspecified (Site unspecified)	0.000	0.997	0.002
S27.01 Traumatic pneumothorax (with open wound into thoracic cavity)	0.002	0.997	0.000
M66.4 Spontaneous rupture of other tendons	0.002	0.998	0.000
S52.80 Fracture of other parts of forearm (closed)	0.000	0.998	0.002
M65.19 Other infective (teno)synovitis (Site unspecified)	0.002	0.998	0.000
M65.18 Other infective (teno)synovitis (Other)	0.002	0.998	0.000
M65.17 Other infective (teno)synovitis (Ankle and foot)	0.002	0.998	0.000
M65.16 Other infective (teno)synovitis (Lower leg)	0.002	0.998	0.000
M65.15 Other infective (teno)synovitis (Pelvic region and thigh)	0.002	0.998	0.000
M65.13 Other infective (teno)synovitis (Forearm)	0.002	0.998	0.000
M65.12 Other infective (teno)synovitis (Upper arm)	0.002	0.998	0.000
M65.11 Other infective (teno)synovitis (Shoulder region)	0.002	0.998	0.000
M65.10 Other infective (teno)synovitis (Multiple sites)	0.002	0.998	0.000
M65.83 Other synovitis and tenosynovitis (Forearm)	0.002	0.998	0.000
M84.13 Nonunion of fracture [pseudarthrosis] (Forearm)	0.002	0.998	0.000
E27.5 Adrenomedullary hyperfunction	0.000	0.998	0.002
E27.0 Other adrenocortical overactivity	0.000	0.998	0.002
M24.16 Other articular cartilage disorders (Lower leg)	0.000	0.998	0.002
I98.2 Oesophageal varices in diseases classified elsewhere	0.002	0.998	0.000
M65.89 Other synovitis and tenosynovitis (Site unspecified)	0.002	0.998	0.000
M65.88 Other synovitis and tenosynovitis (Other)	0.002	0.998	0.000
M65.85 Other synovitis and tenosynovitis (Pelvic region and thigh)	0.002	0.998	0.000
M65.82 Other synovitis and tenosynovitis (Upper arm)	0.002	0.998	0.000
M65.80 Other synovitis and tenosynovitis (Multiple sites)	0.002	0.998	0.000
M65.09 Abscess of tendon sheath (Site unspecified)	0.002	0.998	0.000
M65.08 Abscess of tendon sheath (Other)	0.002	0.998	0.000
M65.07 Abscess of tendon sheath (Ankle and foot)	0.002	0.998	0.000
M65.06 Abscess of tendon sheath (Lower leg)	0.002	0.998	0.000
M65.05 Abscess of tendon sheath (Pelvic region and thigh)	0.002	0.998	0.000
M65.04 Abscess of tendon sheath (Hand)	0.002	0.998	0.000
M65.03 Abscess of tendon sheath (Forearm)	0.002	0.998	0.000
M65.02 Abscess of tendon sheath (Upper arm)	0.002	0.998	0.000
M65.01 Abscess of tendon sheath (Shoulder region)	0.002	0.998	0.000
M65.00 Abscess of tendon sheath (Multiple sites)	0.002	0.998	0.000
S52.1 Fracture of upper end of radius	0.000	0.998	0.002
Z88.9 Personal history of allergy to unspecified drugs, medicaments and biological substances	0.002	0.998	0.000
M65.43 Radial styloid tenosynovitis [de Quervain] (Forearm)	0.002	0.998	0.000
C15.4 Middle third of oesophagus	0.002	0.998	0.000
C79.7 Secondary malignant neoplasm of adrenal gland	0.000	0.998	0.002
D10.3 Other and unspecified parts of mouth	0.000	0.998	0.002
Z45.0 Adjustment and management of cardiac pacemaker	0.000	0.998	0.002
M65.49 Radial styloid tenosynovitis [de Quervain]-Site unspec	0.002	0.998	0.000
M65.48 Radial styloid tenosynovitis [de Quervain]-Other	0.002	0.998	0.000
M65.47 Radial styloid tenosynovitis [de Quervain]-Ankle/foot	0.002	0.998	0.000
M65.46 Radial styloid tenosynovitis [de Quervain]-Lower leg	0.002	0.998	0.000
M65.45 Radial styloid tenosynovitis [de Quervain]-Pelvic/thigh	0.002	0.998	0.000
M65.42 Radial styloid tenosynovitis [de Quervain]-Upper arm	0.002	0.998	0.000
M65.41 Radial styloid tenosynovitis [de Quervain]-Shldr region	0.002	0.998	0.000
M65.40 Radial styloid tenosynovitis [de Quervain] (Multiple sites)	0.002	0.998	0.000
Z43.6 Attention to other artificial openings of urinary tract	0.002	0.998	0.000
M65.29 Calcific tendinitis (Site unspecified)	0.002	0.998	0.000
M65.28 Calcific tendinitis (Other)	0.002	0.998	0.000
M65.27 Calcific tendinitis (Ankle and foot)	0.002	0.998	0.000
M65.26 Calcific tendinitis (Lower leg)	0.002	0.998	0.000
M65.25 Calcific tendinitis (Pelvic region and thigh)	0.002	0.998	0.000
M65.24 Calcific tendinitis (Hand)	0.002	0.998	0.000
M65.23 Calcific tendinitis (Forearm)	0.002	0.998	0.000
M65.22 Calcific tendinitis (Upper arm)	0.002	0.998	0.000
M65.20 Calcific tendinitis (Multiple sites)	0.002	0.998	0.000
E27.9 Disorder of adrenal gland, unspecified	0.000	0.998	0.002
N30 Cystitis	0.000	0.998	0.002
H11 Other disorders of conjunctiva	0.002	0.998	0.000
M65.87 Other synovitis and tenosynovitis (Ankle and foot)	0.002	0.998	0.000
C81.9 Hodgkin's disease, unspecified	0.000	0.998	0.002
M19.9 Arthrosis, unspecified	0.000	0.998	0.002
N85.2 Hypertrophy of uterus	0.000	0.998	0.002
D09.0 Bladder	0.000	0.998	0.002
H40.9 Glaucoma, unspecified	0.002	0.998	0.000
K14.5 Plicated tongue	0.002	0.998	0.000
K14.4 Atrophy of tongue papillae	0.002	0.998	0.000
K14.2 Median rhomboid glossitis	0.002	0.998	0.000
K14.1 Geographic tongue	0.002	0.998	0.000
C80.0 Malignant neoplasm, primary site unknown, so stated	0.000	0.998	0.002
S32.4 Fracture of acetabulum	0.002	0.998	0.000
M19 Other arthrosis	0.000	0.998	0.002
E23.0 Hypopituitarism	0.000	0.998	0.002
K14.3 Hypertrophy of tongue papillae	0.002	0.998	0.000
M66 Spontaneous rupture of synovium and tendon	0.002	0.998	0.000
M65.21 Calcific tendinitis (Shoulder region)	0.002	0.998	0.000
C34.9 Bronchus or lung, unspecified	0.000	0.998	0.002
M84.14 Nonunion of fracture [pseudarthrosis] (Hand)	0.002	0.998	0.000
M88.90 Paget's disease of bone, unspecified (Multiple sites)	0.000	0.998	0.002
M88.9 Paget's disease of bone, unspecified	0.000	0.998	0.002
J42 Unspecified chronic bronchitis	0.002	0.998	0.000
B07 Viral warts	0.000	0.998	0.002
N76.0 Acute vaginitis	0.000	0.998	0.002
M19.95 Arthrosis, unspecified (Pelvic region and thigh)	0.000	0.998	0.002
M66.49 Spontaneous rupture of other tendons (Site unspecified)	0.002	0.998	0.000
M66.48 Spontaneous rupture of other tendons (Other)	0.002	0.998	0.000
M66.47 Spontaneous rupture of other tendons (Ankle and foot)	0.002	0.998	0.000
M66.45 Spontaneous rupture of other tendons (Pelvic region and thigh)	0.002	0.998	0.000
M66.44 Spontaneous rupture of other tendons (Hand)	0.002	0.998	0.000
M66.43 Spontaneous rupture of other tendons (Forearm)	0.002	0.998	0.000
M66.42 Spontaneous rupture of other tendons (Upper arm)	0.002	0.998	0.000
M66.40 Spontaneous rupture of other tendons (Multiple sites)	0.002	0.998	0.000
F33.2 Recurrent depressive disorder, current episode severe without psychotic symptoms	0.002	0.998	0.000
M66.0 Rupture of popliteal cyst	0.002	0.998	0.000
M92.6 Juvenile osteochondrosis of tarsus	0.002	0.998	0.000
M65.44 Radial styloid tenosynovitis [de Quervain] (Hand)	0.002	0.998	0.000
F41.0 Panic disorder [episodic paroxysmal anxiety]	0.002	0.998	0.000
R20.2 Paraesthesia of skin	0.000	0.998	0.002
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	0.000	0.998	0.002
M66.06 Rupture of popliteal cyst-Lower leg	0.002	0.998	0.000
K14.6 Glossodynia	0.002	0.998	0.000
K60.1 Chronic anal fissure	0.000	0.998	0.002
M65.81 Other synovitis and tenosynovitis (Shoulder region)	0.002	0.998	0.000
M88.95 Paget's disease of bone, unspecified (Pelvic region and thigh)	0.000	0.998	0.002
S52.11 Fracture of upper end of radius (open)	0.000	0.998	0.002
H17.9 Corneal scar and opacity, unspecified	0.000	0.998	0.002
O82.0 Delivery by elective Caesarean section	0.000	0.998	0.002
M66.41 Spontaneous rupture of other tendons (Shoulder region)	0.002	0.998	0.000
M84.16 Nonunion of fracture [pseudarthrosis] (Lower leg)	0.002	0.998	0.000
S02.20 Fracture of nasal bones (closed)	0.002	0.998	0.000
H11.2 Conjunctival scars	0.002	0.998	0.000
I98.3 Oesophageal varices with bleeding in diseases classified elsewhere	0.002	0.998	0.000
E27.8 Other specified disorders of adrenal gland	0.000	0.998	0.002
G91.2 Normal-pressure hydrocephalus	0.000	0.998	0.002
M94.08 Chondrocostal junction syndrome [Tietze]-Other	0.002	0.998	0.000
H65.4 Other chronic nonsuppurative otitis media	0.000	0.998	0.002
S52.8 Fracture of other parts of forearm	0.000	0.998	0.002
D17.2 Benign lipomatous neoplasm of skin and subcutaneous tissue of limbs	0.002	0.998	0.000
I70.2 Atherosclerosis of arteries of the extremities	0.002	0.998	0.000
K50.0 Crohn's disease of small intestine	0.000	0.998	0.002
M66.3 Spontaneous rupture of flexor tendons	0.002	0.998	0.000
M19.92 Arthrosis, unspecified (Upper arm)	0.000	0.998	0.002
O32.8 Maternal care for other malpresentation of foetus	0.000	0.998	0.002
Z34.9 Supervision of normal pregnancy, unspecified	0.000	0.998	0.002
S32.41 Fracture of acetabulum (open)	0.002	0.998	0.000
G91.9 Hydrocephalus, unspecified	0.000	0.998	0.002
M19.8 Other specified arthrosis	0.000	0.998	0.002
T93.9 Sequelae of unspecified injury of lower limb	0.002	0.998	0.000
I97.8 Other postprocedural disorders of circulatory system, not elsewhere classified	0.002	0.998	0.000
K85.1 Biliary acute pancreatitis	0.000	0.998	0.002
N30.3 Trigonitis	0.000	0.998	0.002
O82.9 Delivery by Caesarean section, unspecified	0.000	0.998	0.002
E27.4 Other and unspecified adrenocortical insufficiency	0.000	0.998	0.002
M66.1 Rupture of synovium	0.002	0.998	0.000
M46.18 Sacroiliitis, not elsewhere classified-Sacral/sacrococ	0.002	0.998	0.000
R20.8 Other and unspecified disturbances of skin sensation	0.000	0.998	0.002
M88.98 Paget's disease of bone, unspecified (Other)	0.000	0.998	0.002

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations