TreeWAS – Variant ID: rs4821261

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
O70.0 First degree perineal laceration during delivery	0.000	0.968	0.032
I24.8 Other forms of acute ischaemic heart disease	0.000	0.978	0.022
I24 Other acute ischaemic heart diseases	0.000	0.985	0.015
E87.1 Hypo-osmolality and hyponatraemia	0.014	0.986	0.000
I24.0 Coronary thrombosis not resulting in myocardial infarction	0.000	0.986	0.014
I24.1 Dressler's syndrome	0.000	0.988	0.011
C85.9 Non-Hodgkin's lymphoma, unspecified type	0.000	0.989	0.011
I35.1 Aortic (valve) insufficiency	0.011	0.989	0.000
L90.5 Scar conditions and fibrosis of skin	0.000	0.990	0.010
C77.3 Axillary and upper limb lymph nodes	0.000	0.990	0.010
I22.9 Subsequent myocardial infarction of unspecified site	0.000	0.990	0.010
H90.3 Sensorineural hearing loss, bilateral	0.009	0.991	0.000
H90 Conductive and sensorineural hearing loss	0.009	0.991	0.000
I22 Subsequent myocardial infarction	0.000	0.991	0.009
H90.5 Sensorineural hearing loss, unspecified	0.009	0.991	0.000
I24.9 Acute ischaemic heart disease, unspecified	0.000	0.992	0.008
I22.1 Subsequent myocardial infarction of inferior wall	0.000	0.992	0.008
H90.4 Sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side	0.007	0.993	0.000
H90.1 Conductive hearing loss, unilateral with unrestricted hearing on the contralateral side	0.007	0.993	0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma	0.000	0.993	0.007
I20-I25 Ischaemic heart diseases	0.000	0.993	0.007
H90.0 Conductive hearing loss, bilateral	0.007	0.993	0.000
H90.2 Conductive hearing loss, unspecified	0.007	0.993	0.000
S62.60 Fracture of other finger (closed)	0.000	0.993	0.007
I22.0 Subsequent myocardial infarction of anterior wall	0.000	0.993	0.007
M23.33 Other meniscus derangements (Medial collateral ligament or Other and unspecified medial meniscus)	0.000	0.993	0.007
I35 Nonrheumatic aortic valve disorders	0.007	0.993	0.000
H90.7 Mixed conductive and sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side	0.007	0.993	0.000
H90.6 Mixed conductive and sensorineural hearing loss, bilateral	0.007	0.993	0.000
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified	0.000	0.993	0.007
H90.8 Mixed conductive and sensorineural hearing loss, unspecified	0.006	0.993	0.000
C85.1 B-cell lymphoma, unspecified	0.000	0.994	0.006
O48 Prolonged pregnancy	0.000	0.994	0.006
O46.9 Antepartum haemorrhage, unspecified	0.000	0.994	0.006
I21.4 Acute subendocardial myocardial infarction	0.000	0.994	0.006
I21 Acute myocardial infarction	0.000	0.994	0.006
J90 Pleural effusion, not elsewhere classified	0.000	0.994	0.006
I35.9 Aortic valve disorder, unspecified	0.006	0.994	0.000
C85.2 Mediastinal (thymic) large B-cell lymphoma	0.000	0.994	0.006
I21.9 Acute myocardial infarction, unspecified	0.000	0.994	0.006
O70 Perineal laceration during delivery	0.000	0.994	0.006
I22.8 Subsequent myocardial infarction of other sites	0.000	0.994	0.005
I35.2 Aortic (valve) stenosis with insufficiency	0.006	0.994	0.000
I35.0 Aortic (valve) stenosis	0.006	0.994	0.000
S62.30 Fracture of other metacarpal bone (closed)	0.000	0.995	0.005
S62.6 Fracture of other finger	0.000	0.995	0.005
C85.0 Lymphosarcoma	0.000	0.995	0.005
O41.8 Other specified disorders of amniotic fluid and membranes	0.000	0.995	0.005
I62.0 Subdural haemorrhage (acute) (nontraumatic)	0.000	0.995	0.005
O46 Antepartum haemorrhage, not elsewhere classified	0.000	0.995	0.005
I23 Certain current complications following acute myocardial infarction	0.000	0.995	0.005
G30.9 Alzheimer's disease, unspecified	0.005	0.995	0.000
I35.8 Other aortic valve disorders	0.005	0.995	0.000
S62.3 Fracture of other metacarpal bone	0.000	0.995	0.005
O41 Other disorders of amniotic fluid and membranes	0.000	0.995	0.005
O36.0 Maternal care for rhesus isoimmunisation	0.000	0.995	0.005
I21.3 Acute transmural myocardial infarction of unspecified site	0.000	0.995	0.005
S62 Fracture at wrist and hand level	0.000	0.995	0.005
I21.2 Acute transmural myocardial infarction of other sites	0.000	0.995	0.005
C54.1 Endometrium	0.005	0.995	0.000
O36.9 Maternal care for foetal problem, unspecified	0.000	0.995	0.005
O36 Maternal care for other known or suspected foetal problems	0.000	0.995	0.005
I21.X Presumed acute myicardial infaction (unconfirmed)	0.000	0.995	0.005
C91.4 Hairy-cell leukaemia	0.000	0.995	0.005
F00.9 Dementia in Alzheimer's disease, unspecified	0.005	0.995	0.000
R09.1 Pleurisy	0.005	0.995	0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems	0.000	0.995	0.005
O41.0 Oligohydramnios	0.000	0.995	0.004
O70.9 Perineal laceration during delivery, unspecified	0.000	0.996	0.004
G30 Alzheimer's disease	0.004	0.996	0.000
O30.0 Twin pregnancy	0.000	0.996	0.004
O30 Multiple gestation	0.000	0.996	0.004
S72.00 Fracture of neck of femur (closed)	0.004	0.996	0.000
O70.3 Fourth degree perineal laceration during delivery	0.000	0.996	0.004
J03.9 Acute tonsillitis, unspecified	0.000	0.996	0.004
F00 Dementia in Alzheimer's disease	0.004	0.996	0.000
G30.0 Alzheimer's disease with early onset	0.004	0.996	0.000
C91 Lymphoid leukaemia	0.000	0.996	0.004
S62.2 Fracture of first metacarpal bone	0.000	0.996	0.004
I05.0 Mitral stenosis	0.000	0.996	0.004
O36.4 Maternal care for intra-uterine death	0.000	0.996	0.004
S62.8 Fracture of other and unspecified parts of wrist and hand	0.000	0.996	0.004
C85.7 Other specified types of non-Hodgkin's lymphoma	0.000	0.996	0.004
O46.0 Antepartum haemorrhage with coagulation defect	0.000	0.996	0.004
S62.31 Fracture of other metacarpal bone (open)	0.000	0.996	0.004
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction	0.000	0.996	0.004
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction	0.000	0.996	0.004
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction	0.000	0.996	0.004
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction	0.000	0.996	0.004
I23.1 Atrial septal defect as current complication following acute myocardial infarction	0.000	0.996	0.004
I23.0 Haemopericardium as current complication following acute myocardial infarction	0.000	0.996	0.004
I23.8 Other current complications following acute myocardial infarction	0.000	0.996	0.004
O46.8 Other antepartum haemorrhage	0.000	0.996	0.004
O41.9 Disorder of amniotic fluid and membranes, unspecified	0.000	0.996	0.004
O41.1 Infection of amniotic sac and membranes	0.000	0.996	0.004
L02.4 Cutaneous abscess, furuncle and carbuncle of limb	0.000	0.996	0.004
S62.1 Fracture of other carpal bone(s)	0.000	0.996	0.004
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.000	0.996	0.004
Z13.5 Special screening examination for eye and ear disorders	0.000	0.996	0.004
I05 Rheumatic mitral valve diseases	0.000	0.996	0.004
I23.2 Ventricular septal defect as current complication following acute myocardial infarction	0.000	0.996	0.003
O35 Maternal care for known or suspected foetal abnormality and damage	0.000	0.996	0.004
S62.0 Fracture of navicular [scaphoid] bone of hand	0.000	0.996	0.004
C84 Peripheral and cutaneous T-cell lymphomas	0.000	0.996	0.004
O70.2 Third degree perineal laceration during delivery	0.000	0.996	0.004
S62.5 Fracture of thumb	0.000	0.996	0.004
G30.1 Alzheimer's disease with late onset	0.004	0.996	0.000
I05.2 Mitral stenosis with insufficiency	0.000	0.996	0.004
F02 Dementia in other diseases classified elsewhere	0.004	0.996	0.000
O36.3 Maternal care for signs of foetal hypoxia	0.000	0.996	0.004
C91.5 Adult T-cell leukaemia	0.000	0.996	0.004
F00.0 Dementia in Alzheimer's disease with early onset	0.003	0.996	0.000
O36.7 Maternal care for viable foetus in abdominal pregnancy	0.000	0.996	0.003
G31.9 Degenerative disease of nervous system, unspecified	0.004	0.996	0.000
O36.6 Maternal care for excessive foetal growth	0.000	0.996	0.004
G30.8 Other Alzheimer's disease	0.003	0.996	0.000
F00-F09 Organic, including symptomatic, mental disorders	0.004	0.996	0.000
I05.9 Mitral valve disease, unspecified	0.000	0.996	0.004
T39.0 Salicylates	0.000	0.996	0.004
O36.5 Maternal care for poor foetal growth	0.000	0.996	0.003
S62.20 Fracture of first metacarpal bone (closed)	0.000	0.996	0.003
F02.0 Dementia in Pick's disease	0.003	0.996	0.000
C84.8 Cutaneous T-cell lymphoma, unspecified	0.000	0.997	0.003
O45 Premature separation of placenta [abruptio placentae]	0.000	0.997	0.003
I05.1 Rheumatic mitral insufficiency	0.000	0.997	0.003
C95 Leukaemia of unspecified cell type	0.000	0.997	0.003
F03 Unspecified dementia	0.003	0.997	0.000
S62.80 Fracture of other and unspecified parts of wrist and hand (closed)	0.000	0.997	0.003
O36.2 Maternal care for hydrops foetalis	0.000	0.997	0.003
S62.4 Multiple fractures of metacarpal bones	0.000	0.997	0.003
O30.9 Multiple gestation, unspecified	0.000	0.997	0.003
O30.8 Other multiple gestation	0.000	0.997	0.003
O30.2 Quadruplet pregnancy	0.000	0.997	0.003
C91.0 Acute lymphoblastic leukaemia	0.000	0.997	0.003
C88 Malignant immunoproliferative diseases	0.000	0.997	0.003
O36.1 Maternal care for other isoimmunisation	0.000	0.997	0.003
N84.1 Polyp of cervix uteri	0.003	0.997	0.000
S68.2 Traumatic amputation of two or more fingers alone (complete)(partial)	0.000	0.997	0.003
O31 Complications specific to multiple gestation	0.000	0.997	0.003
C84.5 Other and unspecified T-cell lymphomas	0.000	0.997	0.003
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)	0.000	0.997	0.003
C91.8 Mature B-cell leukaemia Burkitt-type	0.000	0.997	0.003
C91.7 Other lymphoid leukaemia	0.000	0.997	0.003
C91.6 Prolymphocytic leukaemia of T-cell type	0.000	0.997	0.003
C91.3 Prolymphocytic leukaemia	0.000	0.997	0.003
C91.2 Subacute lymphocytic leukaemia	0.000	0.997	0.003
F00.1 Dementia in Alzheimer's disease with late onset	0.003	0.997	0.000
R09 Other symptoms and signs involving the circulatory and respiratory systems	0.003	0.997	0.000
S62.21 Fracture of first metacarpal bone (open)	0.000	0.997	0.003
S62.50 Fracture of thumb (closed)	0.000	0.997	0.003
L90 Atrophic disorders of skin	0.000	0.997	0.003
O30.1 Triplet pregnancy	0.000	0.997	0.003
S62.7 Multiple fractures of fingers	0.000	0.997	0.003
O44 Placenta praevia	0.000	0.997	0.003
S62.81 Fracture of other and unspecified parts of wrist and hand (open)	0.000	0.997	0.003
F00.2 Dementia in Alzheimer's disease, atypical or mixed type	0.003	0.997	0.000
O35.1 Maternal care for (suspected) chromosomal abnormality in foetus	0.000	0.997	0.003
C54 Malignant neoplasm of corpus uteri	0.003	0.997	0.000
F02.8 Dementia in other specified diseases classified elsewhere	0.003	0.997	0.000
O33 Maternal care for known or suspected disproportion	0.000	0.997	0.003
F02.3 Dementia in Parkinson's disease	0.003	0.997	0.000
C83 Diffuse non-Hodgkin's lymphoma	0.000	0.997	0.003
F01 Vascular dementia	0.003	0.997	0.000
C88.0 Waldenstrom's macroglobulinaemia	0.000	0.997	0.003
S62.61 Fracture of other finger (open)	0.000	0.997	0.003
C95.0 Acute leukaemia of unspecified cell type	0.000	0.997	0.003
E88 Other metabolic disorders	0.000	0.997	0.003
G31 Other degenerative diseases of nervous system, not elsewhere classified	0.003	0.997	0.000
J47 Bronchiectasis	0.003	0.997	0.000
S68 Traumatic amputation of wrist and hand	0.000	0.997	0.003
O35.2 Maternal care for (suspected) hereditary disease in foetus	0.000	0.997	0.003
C86 Other specified types of T/NK-cell lymphoma	0.000	0.997	0.003
S62.10 Fracture of other carpal bone(s) (closed)	0.000	0.997	0.003
S62.11 Fracture of other carpal bone(s) (open)	0.000	0.997	0.003
R09.8 Other specified symptoms and signs involving the circulatory and respiratory systems	0.003	0.997	0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue	0.000	0.997	0.003
M24.16 Other articular cartilage disorders (Lower leg)	0.000	0.997	0.003
C94 Other leukaemias of specified cell type	0.000	0.997	0.003
F06 Other mental disorders due to brain damage and dysfunction and to physical disease	0.003	0.997	0.000
I62 Other nontraumatic intracranial haemorrhage	0.000	0.997	0.003
C84.0 Mycosis fungoides	0.000	0.997	0.003
F07 Personality and behavioural disorders due to brain disease, damage and dysfunction	0.003	0.997	0.000
F09 Unspecified organic or symptomatic mental disorder	0.003	0.997	0.000
O40 Polyhydramnios	0.000	0.997	0.003
S60-S69 Injuries to the wrist and hand	0.000	0.997	0.003
O35.8 Maternal care for other (suspected) foetal abnormality and damage	0.000	0.997	0.003
O42 Premature rupture of membranes	0.000	0.997	0.003
O35.7 Maternal care for (suspected) damage to foetus by other medical procedures	0.000	0.997	0.003
O35.6 Maternal care for (suspected) damage to foetus by radiation	0.000	0.997	0.003
O35.5 Maternal care for (suspected) damage to foetus by drugs	0.000	0.997	0.003
O35.4 Maternal care for (suspected) damage to foetus from alcohol	0.000	0.997	0.003
O35.3 Maternal care for (suspected) damage to foetus from viral disease in mother	0.000	0.997	0.003
O42.9 Premature rupture of membranes, unspecified	0.000	0.997	0.003
R09.0 Asphyxia	0.003	0.997	0.000
Z37.0 Single live birth	0.000	0.997	0.003
G30-G32 Other degenerative diseases of the nervous system	0.003	0.997	0.000
S62.01 Fracture of navicular [scaphoid] bone of hand (open)	0.000	0.997	0.003
C84.9 Mature T/NK-cell lymphoma, unspecified	0.000	0.997	0.003
C84.7 Anaplastic large cell lymphoma, ALK-negative	0.000	0.997	0.003
C84.6 Anaplastic large cell lymphoma, ALK-positive	0.000	0.997	0.003
C84.3 Lymphoepithelioid lymphoma	0.000	0.997	0.003
C84.2 T-zone lymphoma	0.000	0.997	0.003
C84.1 Sezary's diease	0.000	0.997	0.003
C91.1 Chronic lymphocytic leukaemia	0.000	0.997	0.003
F02.4 Dementia in human immunodeficiency virus [HIV] disease	0.003	0.997	0.000
F02.2 Dementia in Huntington's disease	0.003	0.997	0.000
F02.1 Dementia in Creutzfeldt-Jakob disease	0.003	0.997	0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	0.000	0.997	0.003
O35.9 Maternal care for (suspected) foetal abnormality and damage, unspecified	0.000	0.997	0.003
S62.00 Fracture of navicular [scaphoid] bone of hand (closed)	0.000	0.997	0.003
C71.9 Brain, unspecified	0.000	0.997	0.003
M06.9 Rheumatoid arthritis, unspecified	0.000	0.997	0.003
S63.4 Traumatic rupture of ligament of finger at metacarpophalangeal and interphalangeal joint(s)	0.000	0.997	0.003
C95.1 Chronic leukaemia of unspecified cell type	0.000	0.997	0.003
R10.1 Pain localised to upper abdomen	0.003	0.997	0.000
C93 Monocytic leukaemia	0.000	0.997	0.003
F04 Organic amnesic syndrome, not induced by alcohol and other psychoactive substances	0.003	0.997	0.000
G31.0 Circumscribed brain atrophy	0.003	0.997	0.000
C84.4 Peripheral T-cell lymphoma	0.000	0.997	0.003
H90-H95 Other disorders of ear	0.003	0.997	0.000
C83.9 Diffuse non-Hodgkin's lymphoma, unspecified	0.000	0.997	0.003
F01.9 Vascular dementia, unspecified	0.003	0.997	0.000
O35.0 Maternal care for (suspected) central nervous system malformation in foetus	0.000	0.997	0.003
O45.8 Other premature separation of placenta	0.000	0.997	0.003
O45.0 Premature separation of placenta with coagulation defect	0.000	0.997	0.003
C95.9 Leukaemia, unspecified	0.000	0.997	0.003
C95.7 Other leukaemia of unspecified cell type	0.000	0.997	0.003
C95.2 Subacute leukaemia of unspecified cell type	0.000	0.997	0.003
I21.1 Acute transmural myocardial infarction of inferior wall	0.000	0.997	0.003
I62.1 Nontraumatic extradural haemorrhage	0.000	0.997	0.003
N81.5 Vaginal enterocele	0.003	0.997	0.000
S72.0 Fracture of neck of femur	0.003	0.997	0.000
O43 Placental disorders	0.000	0.997	0.003
I05.8 Other mitral valve diseases	0.000	0.997	0.003
S62.41 Multiple fractures of metacarpal bones (open)	0.000	0.997	0.002
C83.5 Lymphoblastic (diffuse)	0.000	0.997	0.003
R09.3 Abnormal sputum	0.003	0.997	0.000
S64.2 Injury of radial nerve at wrist and hand level	0.000	0.997	0.003
C88.9 Malignant immunoproliferative disease, unspecified	0.000	0.997	0.003
C88.7 Other malignant immunoproliferative diseases	0.000	0.997	0.003
C88.3 Immunoproliferative small intestinal disease	0.000	0.997	0.003
C88.2 Gamma heavy chain disease	0.000	0.997	0.003
C88.1 Alpha heavy chain disease	0.000	0.997	0.003
O45.9 Premature separation of placenta, unspecified	0.000	0.997	0.002
C92 Myeloid leukaemia	0.000	0.997	0.003
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level	0.000	0.997	0.003
C91.9 Lymphoid leukaemia, unspecified	0.000	0.997	0.002
N75.0 Cyst of Bartholin's gland	0.003	0.997	0.000
O44.1 Placenta praevia with haemorrhage	0.000	0.997	0.003
F06.8 Other specified mental disorders due to brain damage and dysfunction and to physical disease	0.003	0.997	0.000
E88.1 Lipodystrophy, not elsewhere classified	0.000	0.997	0.003
O31.0 Papyraceous foetus	0.000	0.997	0.002
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	0.000	0.997	0.003
M06.92 Rheumatoid arthritis, unspecified (Upper arm)	0.000	0.997	0.003
C83.0 Small cell (diffuse)	0.000	0.997	0.003
S68.1 Traumatic amputation of other single finger (complete)(partial)	0.000	0.997	0.003
C88.4 Extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue [MALT-lymphoma]	0.000	0.997	0.002
E88.9 Metabolic disorder, unspecified	0.000	0.997	0.002
E88.2 Lipomatosis, not elsewhere classified	0.000	0.997	0.002
F01.1 Multi-infarct dementia	0.002	0.997	0.000
O31.8 Other complications specific to multiple gestation	0.000	0.997	0.002
M06.98 Rheumatoid arthritis, unspecified (Other)	0.000	0.997	0.002
C83.1 Small cleaved cell (diffuse)	0.000	0.997	0.002
F06.9 Unspecified mental disorder due to brain damage and dysfunction and to physical disease	0.002	0.997	0.000
L90.6 Striae atrophicae	0.000	0.997	0.002
L90.4 Acrodermatitis chronica atrophicans	0.000	0.997	0.002
L90.3 Atrophoderma of Pasini and Pierini	0.000	0.997	0.002
L90.2 Anetoderma of Jadassohn-Pellizzari	0.000	0.997	0.002
L90.1 Anetoderma of Schweninger-Buzzi	0.000	0.997	0.002
O31.1 Continuing pregnancy after abortion of one foetus or more	0.000	0.997	0.002
Q63.0 Accessory kidney	0.003	0.997	0.000
C54.8 Overlapping lesion of corpus uteri	0.002	0.997	0.000
C54.3 Fundus uteri	0.002	0.997	0.000
C54.2 Myometrium	0.002	0.997	0.000
C54.0 Isthmus uteri	0.002	0.997	0.000
C86.5 Angioimmunoblastic T-cell lymphoma	0.000	0.997	0.002
E88.3 Tumour lysis syndrome	0.000	0.997	0.002
F01.8 Other vascular dementia	0.002	0.997	0.000
F01.3 Mixed cortical and subcortical vascular dementia	0.002	0.997	0.000
F01.2 Subcortical vascular dementia	0.002	0.997	0.000
F01.0 Vascular dementia of acute onset	0.002	0.997	0.000
F06.2 Organic delusional [schizophrenia-like] disorder	0.002	0.997	0.000
I62.9 Intracranial haemorrhage (nontraumatic), unspecified	0.000	0.997	0.002
L90.9 Atrophic disorder of skin, unspecified	0.000	0.997	0.002
O33.8 Maternal care for disproportion of other origin	0.000	0.997	0.002
O33.7 Maternal care for disproportion due to other foetal deformities	0.000	0.997	0.002
O33.6 Maternal care for disproportion due to hydrocephalic foetus	0.000	0.997	0.002
O33.4 Maternal care for disproportion of mixed maternal and foetal origin	0.000	0.997	0.002
O33.3 Maternal care for disproportion due to outlet contraction of pelvis	0.000	0.997	0.002
O33.2 Maternal care for disproportion due to inlet contraction of pelvis	0.000	0.997	0.002
O33.1 Maternal care for disproportion due to generally contracted pelvis	0.000	0.997	0.002
O33.0 Maternal care for disproportion due to deformity of maternal pelvic bones	0.000	0.997	0.002
Z37.2 Twins, both liveborn	0.000	0.997	0.003
C83.6 Undifferentiated (diffuse)	0.000	0.997	0.002
C83.4 Immunoblastic (diffuse)	0.000	0.997	0.002
F06.3 Organic mood [affective] disorders	0.002	0.997	0.000
G31.1 Senile degeneration of brain, not elsewhere classified	0.002	0.997	0.000
O31.2 Continuing pregnancy after intra-uterine death of one foetus or more	0.000	0.997	0.002
S68.9 Traumatic amputation of wrist and hand, level unspecified	0.000	0.997	0.002
S68.8 Traumatic amputation of other parts of wrist and hand	0.000	0.997	0.002
S68.4 Traumatic amputation of hand at wrist level	0.000	0.997	0.002
S68.3 Combined traumatic amputation of (part of) finger(s) with other parts of wrist and hand	0.000	0.997	0.002
J91 Pleural effusion in conditions classified elsewhere	0.000	0.997	0.002
M06.93 Rheumatoid arthritis, unspecified (Forearm)	0.000	0.997	0.002
L02.9 Cutaneous abscess, furuncle and carbuncle, unspecified	0.000	0.997	0.002
S67 Crushing injury of wrist and hand	0.000	0.997	0.002
C71.8 Overlapping lesion of brain	0.000	0.998	0.002
C86.6 Primary cutaneous CD30-positive T-cell proliferations	0.000	0.998	0.002
C86.4 Blastic NK-cell lymphoma	0.000	0.998	0.002
C86.3 Subcutaneous panniculitis-like T-cell lymphoma	0.000	0.998	0.002
C86.2 Enteropathy-type (intestinal) T-cell lymphoma	0.000	0.998	0.002
C86.1 Hepatosplenic T-cell lymphoma	0.000	0.998	0.002
C86.0 Extranodal NK/T-cell lymphoma, nasal type	0.000	0.998	0.002
C94.6 Myelodysplastic and myeloproliferative disease, not elsewhere classified	0.000	0.998	0.002
Z37 Outcome of delivery	0.000	0.998	0.002
C83.2 Mixed small and large cell (diffuse)	0.000	0.998	0.002
F07.9 Unspecified organic personality and behavioural disorder due to brain disease, damage and dysfunction	0.002	0.998	0.000
F07.2 Postconcussional syndrome	0.002	0.998	0.000
S63.0 Dislocation of wrist	0.000	0.998	0.002
C96.9 Malignant neoplasms of lymphoid, haematopoietic and related tissue, unspecified	0.000	0.998	0.002
C96.8 Histiocytic sarcoma	0.000	0.998	0.002
C96.7 Other specified malignant neoplasms of lymphoid, haematopoietic and related tissue	0.000	0.998	0.002
C96.6 Unifocal Langerhans-cell histiocytosis	0.000	0.998	0.002
C96.5 Multifocal and unisystemic Langerhans-cell histiocytosis	0.000	0.998	0.002
C96.4 Sarcoma of dendritic cells (accessory cells)	0.000	0.998	0.002
C96.3 True histiocytic lymphoma	0.000	0.998	0.002
C96.2 Malignant mast cell tumour	0.000	0.998	0.002
C96.1 Malignant histiocytosis	0.000	0.998	0.002
C96.0 Letterer-Siwe disease	0.000	0.998	0.002
F07.0 Organic personality disorder	0.002	0.998	0.000
G50.0 Trigeminal neuralgia	0.002	0.998	0.000
H91 Other hearing loss	0.002	0.998	0.000
S62.51 Fracture of thumb (open)	0.000	0.998	0.002
C83.7 Burkitt's tumour	0.000	0.998	0.002
C94.7 Other specified leukaemias	0.000	0.998	0.002
C94.5 Acute myelofibrosis	0.000	0.998	0.002
C94.3 Mast cell leukaemia	0.000	0.998	0.002
C94.2 Acute megakaryoblastic leukaemia	0.000	0.998	0.002
C94.1 Chronic erythraemia	0.000	0.998	0.002
C94.0 Acute erythraemia and erythroleukaemia	0.000	0.998	0.002
F06.6 Organic emotionally labile [asthenic] disorder	0.002	0.998	0.000
F06.5 Organic dissociative disorder	0.002	0.998	0.000
F06.4 Organic anxiety disorder	0.002	0.998	0.000
F06.1 Organic catatonic disorder	0.002	0.998	0.000
F06.0 Organic hallucinosis	0.002	0.998	0.000
O42.2 Premature rupture of membranes, labour delayed by therapy	0.000	0.998	0.002
R47.8 Other and unspecified speech disturbances	0.000	0.998	0.002
C92.4 Acute promyelocytic leukaemia	0.000	0.998	0.002
F07.8 Other organic personality and behavioural disorders due to brain disease, damage and dysfunction	0.002	0.998	0.000
F07.1 Postencephalitic syndrome	0.002	0.998	0.000
L02.3 Cutaneous abscess, furuncle and carbuncle of buttock	0.000	0.998	0.002
C71 Malignant neoplasm of brain	0.000	0.998	0.002
C81 Hodgkin's disease	0.000	0.998	0.002
O33.5 Maternal care for disproportion due to unusually large foetus	0.000	0.998	0.002
S64 Injury of nerves at wrist and hand level	0.000	0.998	0.002
J90-J94 Other diseases of pleura	0.000	0.998	0.002
C57.0 Fallopian tube	0.002	0.998	0.000
R09.2 Respiratory arrest	0.002	0.998	0.000
S66 Injury of muscle and tendon at wrist and hand level	0.000	0.998	0.002
C94.4 Acute panmyelosis	0.000	0.998	0.002
L90.8 Other atrophic disorders of skin	0.000	0.998	0.002
S68.0 Traumatic amputation of thumb (complete)(partial)	0.000	0.998	0.002
S62.71 Multiple fractures of fingers (open)	0.000	0.998	0.002
S64.1 Injury of median nerve at wrist and hand level	0.000	0.998	0.002
S65 Injury of blood vessels at wrist and hand level	0.000	0.998	0.002
S62.40 Multiple fractures of metacarpal bones (closed)	0.000	0.998	0.002
C92.0 Acute myeloid leukaemia	0.000	0.998	0.002
O33.9 Maternal care for disproportion, unspecified	0.000	0.998	0.002
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.000	0.998	0.002
C54.9 Corpus uteri, unspecified	0.002	0.998	0.000
C93.9 Monocytic leukaemia, unspecified	0.000	0.998	0.002
C93.7 Other monocytic leukaemia	0.000	0.998	0.002
C93.3 Juvenile myelomonocytic leukaemia	0.000	0.998	0.002
C93.2 Subacute monocytic leukaemia	0.000	0.998	0.002
C93.0 Acute monocytic leukaemia	0.000	0.998	0.002
G32 Other degenerative disorders of nervous system in diseases classified elsewhere	0.002	0.998	0.000
J93 Pneumothorax	0.000	0.998	0.002
H94 Other disorders of ear in diseases classified elsewhere	0.002	0.998	0.000
C71.4 Occipital lobe	0.000	0.998	0.002
C83.8 Other types of diffuse non-Hodgkin's lymphoma	0.000	0.998	0.002
Z37.1 Single stillbirth	0.000	0.998	0.002
S62.70 Multiple fractures of fingers (closed)	0.000	0.998	0.002
C57 Malignant neoplasm of other and unspecified female genital organs	0.002	0.998	0.000
O34 Maternal care for known or suspected abnormality of pelvic organs	0.000	0.998	0.002
C71.3 Parietal lobe	0.000	0.998	0.002
C83.3 Large cell (diffuse)	0.000	0.998	0.002
O43.2 Morbidly adherent placenta	0.000	0.998	0.002
O43.0 Placental transfusion syndromes	0.000	0.998	0.002
C51-C58 Malignant neoplasms of female genital organs	0.002	0.998	0.000
S72.01 Fracture of neck of femur (open)	0.002	0.998	0.000
C92.2 Subacute myeloid leukaemia	0.000	0.998	0.002
J93.8 Other pneumothorax	0.000	0.998	0.002
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified	0.002	0.998	0.000
M62.82 Other specified disorders of muscle (Upper arm)	0.000	0.998	0.002
E88.8 Other specified metabolic disorders	0.000	0.998	0.002
S63.1 Dislocation finger	0.000	0.998	0.002
S66.7 Injury of multiple extensor muscles and tendons at wrist and hand level	0.000	0.998	0.002
C92.8 Acute myeloid leukaemia with multilineage dysplasia	0.000	0.998	0.002
C92.6 Acute myeloid leukaemia with 11q23-abnormality	0.000	0.998	0.002
C92.3 Myeloid sarcoma	0.000	0.998	0.002
O43.9 Placental disorder, unspecified	0.000	0.998	0.002
L02 Cutaneous abscess, furuncle and carbuncle	0.000	0.998	0.002
K05.3 Chronic periodontitis	0.000	0.998	0.002
Z37.3 Twins, one liveborn and one stillborn	0.000	0.998	0.002
C52 Malignant neoplasm of vagina	0.002	0.998	0.000
G31.2 Degeneration of nervous system due to alcohol	0.002	0.998	0.000
M62.8 Other specified disorders of muscle	0.000	0.998	0.002
G31.8 Other specified degenerative diseases of nervous system	0.002	0.998	0.000
H91.2 Sudden idiopathic hearing loss	0.002	0.998	0.000
S61.8 Open wound of other parts of wrist and hand	0.000	0.998	0.002
S66.0 Injury of long flexor muscle and tendon of thumb at wrist and hand level	0.000	0.998	0.002
J93.9 Pneumothorax, unspecified	0.000	0.998	0.002
L90.0 Lichen sclerosus et atrophicus	0.000	0.998	0.002
O34.1 Maternal care for tumour of corpus uteri	0.000	0.998	0.002
S60.8 Other superficial injuries of wrist and hand	0.000	0.998	0.002
S63.3 Traumatic rupture of ligament of wrist and carpus	0.000	0.998	0.002
S66.6 Injury of multiple flexor muscles and tendons at wrist and hand level	0.000	0.998	0.002
M06.96 Rheumatoid arthritis, unspecified (Lower leg)	0.000	0.998	0.002
C93.1 Chronic monocytic leukaemia	0.000	0.998	0.002
H91.0 Ototoxic hearing loss	0.002	0.998	0.000
S63.7 Sprain and strain of other and unspecified parts of hand	0.000	0.998	0.002
S63.2 Multiple dislocations of fingers	0.000	0.998	0.002
C92.5 Acute myelomonocytic leukaemia	0.000	0.998	0.002
H91.1 Presbycusis	0.002	0.998	0.000
J43.9 Emphysema, unspecified	0.002	0.998	0.000
S67.8 Crushing injury of other and unspecified parts of wrist and hand	0.000	0.998	0.002
S61 Open wound of wrist and hand	0.000	0.998	0.002
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.000	0.998	0.002
S72.40 Fracture of lower end of femur (closed)	0.002	0.998	0.000
C92.7 Other myeloid leukaemia	0.000	0.998	0.002
S65.1 Injury of radial artery at wrist and hand level	0.000	0.998	0.002
S67.0 Crushing injury of thumb and other finger(s)	0.000	0.998	0.002
M62.85 Other specified disorders of muscle (Pelvic region and thigh)	0.000	0.998	0.002
C71.6 Cerebellum	0.000	0.998	0.002
H91.9 Hearing loss, unspecified	0.002	0.998	0.000
Z37.5 Other multiple births, all liveborn	0.000	0.998	0.002
C92.9 Myeloid leukaemia, unspecified	0.000	0.998	0.002
Z37.9 Outcome of delivery unspecified	0.000	0.998	0.002
Z37.7 Other multiple births, all stillborn	0.000	0.998	0.002
Z37.6 Other multiple births, some liveborn	0.000	0.998	0.002
Z37.4 Twins, both stillborn	0.000	0.998	0.002
S60 Superficial injury of wrist and hand	0.000	0.998	0.002
S63.5 Sprain and strain of wrist	0.000	0.998	0.002
S65.0 Injury of ulnar artery at wrist and hand level	0.000	0.998	0.002
M62.84 Other specified disorders of muscle (Hand)	0.000	0.998	0.002
C81.4 Lymphocyte-rich classical Hodgkin lymphoma	0.000	0.998	0.002
C81.3 Lymphocytic depletion	0.000	0.998	0.002
H91.3 Deaf mutism, not elsewhere classified	0.002	0.998	0.000
L02.8 Cutaneous abscess, furuncle and carbuncle of other sites	0.000	0.998	0.002
O44.0 Placenta praevia specified as without haemorrhage	0.000	0.998	0.002
C81.0 Lymphocytic predominance	0.000	0.998	0.002
S64.9 Injury of unspecified nerve at wrist and hand level	0.000	0.998	0.002
S64.8 Injury of other nerves at wrist and hand level	0.000	0.998	0.002
J03 Acute tonsillitis	0.000	0.998	0.002
B34.9 Viral infection, unspecified	0.000	0.998	0.002
C71.5 Cerebral ventricle	0.000	0.998	0.002
C81.1 Nodular sclerosis	0.000	0.998	0.002
F33.9 Recurrent depressive disorder, unspecified	0.002	0.998	0.000
S66.4 Injury of intrinsic muscle and tendon of thumb at wrist and hand level	0.000	0.998	0.002
M62.89 Other specified disorders of muscle (Site unspecified)	0.000	0.998	0.002
C81.7 Other Hodgkin's disease	0.000	0.998	0.002
H95.8 Other postprocedural disorders of ear and mastoid process	0.002	0.998	0.000
O32 Maternal care for known or suspected malpresentation of foetus	0.000	0.998	0.002
C71.0 Cerebrum, except lobes and ventricles	0.000	0.998	0.002
H20.9 Iridocyclitis, unspecified	0.000	0.998	0.002
N80.0 Endometriosis of uterus	0.002	0.998	0.000
S65.9 Injury of unspecified blood vessel at wrist and hand level	0.000	0.998	0.002
S65.8 Injury of other blood vessels at wrist and hand level	0.000	0.998	0.002
S65.7 Injury of multiple blood vessels at wrist and hand level	0.000	0.998	0.002
S65.3 Injury of deep palmar arch	0.000	0.998	0.002
S65.2 Injury of superficial palmar arch	0.000	0.998	0.002
S69 Other and unspecified injuries of wrist and hand	0.000	0.998	0.002
M06.00 Seronegative rheumatoid arthritis (Multiple sites)	0.000	0.998	0.002
C57.9 Female genital organ, unspecified	0.002	0.998	0.000
C71.7 Brain stem	0.000	0.998	0.002
C71.2 Temporal lobe	0.000	0.998	0.002
J94.8 Other specified pleural conditions	0.002	0.998	0.000
S66.5 Injury of intrinsic muscle and tendon of other finger at wrist and hand level	0.000	0.998	0.002
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)	0.000	0.998	0.002
G32.0 Subacute combined degeneration of spinal cord in diseases classified elsewhere	0.002	0.998	0.000
H95.9 Postprocedural disorder of ear and mastoid process, unspecified	0.002	0.998	0.000
N93.9 Abnormal uterine and vaginal bleeding, unspecified	0.002	0.998	0.000
S63.6 Sprain and strain of finger(s)	0.000	0.998	0.002
C51 Malignant neoplasm of vulva	0.002	0.998	0.000
H94.8 Other specified disorders of ear in diseases classified elsewhere	0.002	0.998	0.000
H94.0 Acoustic neuritis in infectious and parasitic diseases classified elsewhere	0.002	0.998	0.000
O32.0 Maternal care for unstable lie	0.000	0.998	0.002
O34.0 Maternal care for congenital malformation of uterus	0.000	0.998	0.002
O43.8 Other placental disorders	0.000	0.998	0.002
S66.8 Injury of other muscles and tendons at wrist and hand level	0.000	0.998	0.002
C55 Malignant neoplasm of uterus, part unspecified	0.002	0.998	0.000
C57.7 Other specified female genital organs	0.002	0.998	0.000
C57.4 Uterine adnexa, unspecified	0.002	0.998	0.000
C57.3 Parametrium	0.002	0.998	0.000
C57.2 Round ligament	0.002	0.998	0.000
C57.1 Broad ligament	0.002	0.998	0.000
C81.2 Mixed cellularity	0.000	0.998	0.002
O43.1 Malformation of placenta	0.000	0.998	0.002
C58 Malignant neoplasm of placenta	0.002	0.998	0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.000	0.998	0.002

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations