TreeWAS – Variant ID: rs4845812

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Click here to show this figure without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
K70 Alcoholic liver disease	0.000	0.941	0.059
K70.3 Alcoholic cirrhosis of liver	0.000	0.941	0.059
K70.4 Alcoholic hepatic failure	0.000	0.944	0.056
D70 Agranulocytosis	0.000	0.947	0.053
K72.9 Hepatic failure, unspecified	0.000	0.947	0.053
K70.1 Alcoholic hepatitis	0.000	0.949	0.051
K70.0 Alcoholic fatty liver	0.000	0.951	0.049
K72 Hepatic failure, not elsewhere classified	0.000	0.952	0.048
K70.9 Alcoholic liver disease, unspecified	0.000	0.953	0.047
M07.30 Other psoriatic arthropathies (Multiple sites)	0.000	0.955	0.045
K70.2 Alcoholic fibrosis and sclerosis of liver	0.000	0.956	0.044
K70-K77 Diseases of liver	0.000	0.958	0.042
M07.3 Other psoriatic arthropathies	0.000	0.960	0.040
K73 Chronic hepatitis, not elsewhere classified	0.000	0.961	0.039
K72.0 Acute and subacute hepatic failure	0.000	0.961	0.039
K73.9 Chronic hepatitis, unspecified	0.000	0.961	0.039
K72.1 Chronic hepatic failure	0.000	0.964	0.036
M07.34 Other psoriatic arthropathies (Hand)	0.000	0.966	0.034
M07.36 Other psoriatic arthropathies (Lower leg)	0.000	0.967	0.033
M07.39 Other psoriatic arthropathies (Site unspecified)	0.000	0.968	0.032
M07.37 Other psoriatic arthropathies (Ankle and foot)	0.000	0.968	0.032
J92.0 Pleural plaque with presence of asbestos	0.000	0.969	0.031
K77 Liver disorders in diseases classified elsewhere	0.000	0.970	0.030
Z87.0 Personal history of diseases of the respiratory system	0.000	0.970	0.030
M07.38 Other psoriatic arthropathies (Other)	0.000	0.971	0.029
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)	0.000	0.971	0.029
M07.33 Other psoriatic arthropathies (Forearm)	0.000	0.971	0.029
M07.32 Other psoriatic arthropathies (Upper arm)	0.000	0.971	0.029
M07.31 Other psoriatic arthropathies (Shoulder region)	0.000	0.971	0.029
K73.8 Other chronic hepatitis, not elsewhere classified	0.000	0.971	0.028
K73.1 Chronic lobular hepatitis, not elsewhere classified	0.000	0.971	0.028
K73.0 Chronic persistent hepatitis, not elsewhere classified	0.000	0.971	0.028
K82.4 Cholesterolosis of gallbladder	0.027	0.973	0.000
K73.2 Chronic active hepatitis, not elsewhere classified	0.000	0.975	0.025
K71 Toxic liver disease	0.000	0.976	0.024
K77.8 Liver disorders in other diseases classified elsewhere	0.000	0.978	0.022
K77.0 Liver disorders in infectious and parasitic diseases classified elsewhere	0.000	0.978	0.022
J92 Pleural plaque	0.000	0.981	0.019
K71.9 Toxic liver disease, unspecified	0.000	0.982	0.017
K71.8 Toxic liver disease with other disorders of liver	0.000	0.982	0.017
K71.7 Toxic liver disease with fibrosis and cirrhosis of liver	0.000	0.982	0.017
K71.5 Toxic liver disease with chronic active hepatitis	0.000	0.982	0.017
K71.4 Toxic liver disease with chronic lobular hepatitis	0.000	0.982	0.017
K71.3 Toxic liver disease with chronic persistent hepatitis	0.000	0.982	0.017
K71.2 Toxic liver disease with acute hepatitis	0.000	0.982	0.017
K71.0 Toxic liver disease with cholestasis	0.000	0.982	0.017
I35.0 Aortic (valve) stenosis	0.017	0.983	0.000
M48.06 Spinal stenosis (Lumbar region)	0.000	0.984	0.016
J92.9 Pleural plaque without asbestos	0.000	0.984	0.016
M07 Psoriatic and enteropathic arthropathies	0.000	0.984	0.016
K71.6 Toxic liver disease with hepatitis, not elsewhere classified	0.000	0.984	0.015
K71.1 Toxic liver disease with hepatic necrosis	0.000	0.985	0.014
K75 Other inflammatory liver diseases	0.000	0.987	0.013
D50.9 Iron deficiency anaemia, unspecified	0.000	0.987	0.013
M07.5 Arthropathy in ulcerative colitis	0.000	0.988	0.011
M07.4 Arthropathy in Crohn's disease [regional enteritis]	0.000	0.988	0.011
M07.2 Psoriatic spondylitis	0.000	0.988	0.011
M07.1 Arthritis mutilans	0.000	0.988	0.011
M07.0 Distal interphalangeal psoriatic arthropathy	0.000	0.988	0.011
R06.8 Other and unspecified abnormalities of breathing	0.011	0.989	0.000
M07.6 Other enteropathic arthropathies	0.000	0.989	0.011
I35 Nonrheumatic aortic valve disorders	0.011	0.989	0.000
I35.8 Other aortic valve disorders	0.010	0.990	0.000
K75.4 Autoimmune hepatitis	0.000	0.990	0.010
I35.1 Aortic (valve) insufficiency	0.010	0.990	0.000
K75.2 Nonspecific reactive hepatitis	0.000	0.990	0.009
K75.1 Phlebitis of portal vein	0.000	0.990	0.009
H04.5 Stenosis and insufficiency of lachrymal passages	0.000	0.991	0.009
I61.9 Intracerebral haemorrhage, unspecified	0.000	0.991	0.009
K75.0 Abscess of liver	0.000	0.991	0.009
M07.09 Distal interphalangeal psoriatic arthropathy (Site unspecified)	0.000	0.991	0.008
M07.08 Distal interphalangeal proriatic arthropathy-Other	0.000	0.991	0.008
M07.07 Distal interphalangeal psoriatic arthropathy (Ankle and foot)	0.000	0.991	0.008
M07.06 Distal interphalangeal proriatic arthropathy-Lower leg	0.000	0.991	0.008
M07.05 Distal interphalangeal proriatic arthropathy-Pelvic/thigh	0.000	0.991	0.008
M07.04 Distal interphalangeal psoriatic arthropathy (Hand)	0.000	0.991	0.008
M07.03 Distal interphalangeal proriatic arthropathy-Forearm	0.000	0.991	0.008
M07.02 Distal interphalangeal proriatic arthropathy-Upper arm	0.000	0.991	0.008
M07.01 Distal interphalangeal proriatic arthropathy-Shldr region	0.000	0.991	0.008
M07.00 Distal interphalangeal psoriatic arthropathy (Multiple sites)	0.000	0.991	0.008
M07.19 Arthritis mutilans (Site unspecified)	0.000	0.991	0.008
M07.18 Arthritis mutilans (Other)	0.000	0.991	0.008
M07.17 Arthritis mutilans (Ankle and foot)	0.000	0.991	0.008
M07.16 Arthritis mutilans (Lower leg)	0.000	0.991	0.008
M07.15 Arthritis mutilans (Pelvic region and thigh)	0.000	0.991	0.008
M07.14 Arthritis mutilans (Hand)	0.000	0.991	0.008
M07.13 Arthritis mutilans (Forearm)	0.000	0.991	0.008
M07.12 Arthritis mutilans (Upper arm)	0.000	0.991	0.008
M07.11 Arthritis mutilans (Shoulder region)	0.000	0.991	0.008
M07.10 Arthritis mutilans (Multiple sites)	0.000	0.991	0.008
M07.29 Psoriatic spondylitis (Site unspecified)	0.000	0.991	0.008
M07.28 Psoriatic spondylitis (Other)	0.000	0.991	0.008
M07.27 Psoriatic spondylitis (Ankle and foot)	0.000	0.991	0.008
M07.26 Psoriatic spondylitis (Lower leg)	0.000	0.991	0.008
M07.25 Psoriatic spondylitis (Pelvic region and thigh)	0.000	0.991	0.008
M07.24 Psoriatic spondylitis (Hand)	0.000	0.991	0.008
M07.23 Psoriatic spondylitis (Forearm)	0.000	0.991	0.008
M07.22 Psoriatic spondylitis (Upper arm)	0.000	0.991	0.008
M07.21 Psoriatic spondylitis (Shoulder region)	0.000	0.991	0.008
M07.20 Psoriatic spondylitis (Multiple sites)	0.000	0.991	0.008
M07.49 Arthropathy in Crohn's disease [regional enteritis] (Site unspecified)	0.000	0.991	0.008
M07.48 Arthropathy in Crohn's disease [regional enteritis] (Other)	0.000	0.991	0.008
M07.47 Arthropathy in Crohn's disease [regional enteritis] (Ankle and foot)	0.000	0.991	0.008
M07.46 Arthropathy in Crohn's disease [regional enteritis] (Lower leg)	0.000	0.991	0.008
M07.45 Arthropathy in Crohn's disease [regional enteritis] (Pelvic region and thigh)	0.000	0.991	0.008
M07.44 Arthropathy in Crohn's disease [regional enteritis] (Hand)	0.000	0.991	0.008
M07.43 Arthropathy in Crohn's disease [regional enteritis] (Forearm)	0.000	0.991	0.008
M07.42 Arthropathy in Crohn's disease [regional enteritis] (Upper arm)	0.000	0.991	0.008
M07.41 Arthropathy in Crohn's disease [regional enteritis] (Shoulder region)	0.000	0.991	0.008
M07.40 Arthropathy in Crohn's disease [regional enteritis] (Multiple sites)	0.000	0.991	0.008
M07.59 Arthropathy in ulcerative colitis (Site unspecified)	0.000	0.991	0.008
M07.58 Arthropathy in ulcerative colitis (Other)	0.000	0.991	0.008
M07.57 Arthropathy in ulcerative colitis (Ankle and foot)	0.000	0.991	0.008
M07.56 Arthropathy in ulcerative colitis (Lower leg)	0.000	0.991	0.008
M07.55 Arthropathy in ulcerative colitis (Pelvic region and thigh)	0.000	0.991	0.008
M07.54 Arthropathy in ulcerative colitis (Hand)	0.000	0.991	0.008
M07.53 Arthropathy in ulcerative colitis (Forearm)	0.000	0.991	0.008
M07.52 Arthropathy in ulcerative colitis (Upper arm)	0.000	0.991	0.008
M07.51 Arthropathy in ulcerative colitis (Shoulder region)	0.000	0.991	0.008
M07.50 Arthropathy in ulcerative colitis (Multiple sites)	0.000	0.991	0.008
K75.3 Granulomatous hepatitis, not elsewhere classified	0.000	0.992	0.008
M07.68 Other enteropathic arthropathies (Other)	0.000	0.992	0.008
M07.67 Other enteropathic arthropathies (Ankle and foot)	0.000	0.992	0.008
M07.66 Other enteropathic arthropathies (Lower leg)	0.000	0.992	0.008
M07.65 Other enteropathic arthropathies (Pelvic region and thigh)	0.000	0.992	0.008
M07.64 Other enteropathic arthropathies (Hand)	0.000	0.992	0.008
M07.63 Other enteropathic arthropathies (Forearm)	0.000	0.992	0.008
M07.62 Other enteropathic arthropathies (Upper arm)	0.000	0.992	0.008
M07.61 Other enteropathic arthropathies (Shoulder region)	0.000	0.992	0.008
M07.60 Other enteropathic arthropathies (Multiple sites)	0.000	0.992	0.008
K75.9 Inflammatory liver disease, unspecified	0.000	0.992	0.008
M07.69 Other enteropathic arthropathies (Site unspecified)	0.000	0.992	0.007
D70-D77 Other diseases of blood and blood-forming organs	0.000	0.992	0.008
I61 Intracerebral haemorrhage	0.000	0.993	0.007
I61.4 Intracerebral haemorrhage in cerebellum	0.000	0.993	0.007
I45.1 Other and unspecified right bundle-branch block	0.007	0.993	0.000
D50 Iron deficiency anaemia	0.000	0.993	0.007
J69.0 Pneumonitis due to food and vomit	0.000	0.993	0.006
I61.8 Other intracerebral haemorrhage	0.000	0.994	0.006
I35.2 Aortic (valve) stenosis with insufficiency	0.006	0.994	0.000
I61.5 Intracerebral haemorrhage, intraventricular	0.000	0.994	0.006
D74 Methaemoglobinaemia	0.000	0.994	0.006
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere	0.000	0.994	0.006
D71 Functional disorders of polymorphonuclear neutrophils	0.000	0.994	0.006
I61.1 Intracerebral haemorrhage in hemisphere, cortical	0.000	0.994	0.006
I61.0 Intracerebral haemorrhage in hemisphere, subcortical	0.000	0.994	0.006
I35.9 Aortic valve disorder, unspecified	0.006	0.994	0.000
I61.6 Intracerebral haemorrhage, multiple localised	0.000	0.994	0.005
D50.0 Iron deficiency anaemia secondary to blood loss (chronic)	0.000	0.994	0.006
I61.3 Intracerebral haemorrhage in brain stem	0.000	0.994	0.005
D50-D53 Nutritional anaemias	0.000	0.994	0.006
D73 Diseases of spleen	0.000	0.994	0.006
I61.2 Intracerebral haemorrhage in hemisphere, unspecified	0.000	0.995	0.005
C16.9 Stomach, unspecified	0.005	0.995	0.000
D73.5 Infarction of spleen	0.000	0.995	0.005
L05.9 Pilonidal cyst without abscess	0.005	0.995	0.000
S90.9 Superficial injury of ankle and foot, unspecified	0.005	0.995	0.000
D52 Folate deficiency anaemia	0.000	0.995	0.005
D73.4 Cyst of spleen	0.000	0.995	0.005
D50.1 Sideropenic dysphagia	0.000	0.995	0.004
D73.1 Hypersplenism	0.000	0.995	0.005
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system	0.000	0.995	0.004
L40.5 Arthropathic psoriasis	0.000	0.995	0.005
E24.9 Cushing's syndrome, unspecified	0.005	0.995	0.000
D51.9 Vitamin B12 deficiency anaemia, unspecified	0.000	0.995	0.004
K82 Other diseases of gallbladder	0.005	0.995	0.000
K74 Fibrosis and cirrhosis of liver	0.000	0.996	0.004
D74.9 Methaemoglobinaemia, unspecified	0.000	0.996	0.004
D74.8 Other methaemoglobinaemias	0.000	0.996	0.004
D74.0 Congenital methaemoglobinaemia	0.000	0.996	0.004
D51 Vitamin B12 deficiency anaemia	0.000	0.996	0.004
K76 Other diseases of liver	0.000	0.996	0.004
D73.9 Disease of spleen, unspecified	0.000	0.996	0.004
D73.2 Chronic congestive splenomegaly	0.000	0.996	0.004
J69 Pneumonitis due to solids and liquids	0.000	0.996	0.004
D80.2 Selective deficiency of immunoglobulin A [IgA]	0.000	0.996	0.004
D52.9 Folate deficiency anaemia, unspecified	0.000	0.996	0.004
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.000	0.996	0.004
D80 Immunodeficiency with predominantly antibody defects	0.000	0.996	0.004
D86 Sarcoidosis	0.000	0.996	0.004
D73.3 Abscess of spleen	0.000	0.996	0.004
M31.6 Other giant cell arteritis	0.004	0.996	0.000
D80-D89 Certain disorders involving the immune mechanism	0.000	0.996	0.004
M43.16 Spondylolisthesis (Lumbar region)	0.000	0.996	0.004
I80.1 Phlebitis and thrombophlebitis of femoral vein	0.000	0.996	0.004
K76.1 Chronic passive congestion of liver	0.000	0.996	0.004
K82.3 Fistula of gallbladder	0.004	0.996	0.000
T17.2 Foreign body in pharynx	0.000	0.996	0.004
E24.0 Pituitary-dependent Cushing's disease	0.004	0.996	0.000
D53 Other nutritional anaemias	0.000	0.996	0.004
D52.8 Other folate deficiency anaemias	0.000	0.996	0.004
D52.1 Drug-induced folate deficiency anaemia	0.000	0.996	0.004
D52.0 Dietary folate deficiency anaemia	0.000	0.996	0.004
K82.9 Disease of gallbladder, unspecified	0.004	0.996	0.000
D73.8 Other diseases of spleen	0.000	0.996	0.003
H25.9 Senile cataract, unspecified	0.004	0.996	0.000
D86.9 Sarcoidosis, unspecified	0.000	0.996	0.004
D76.2 Haemophagocytic syndrome, infection-associated	0.000	0.996	0.003
D76.1 Haemophagocytic lymphohistiocytosis	0.000	0.996	0.003
D76.0 Langerhans' cell histiocytosis, not elsewhere classified	0.000	0.996	0.003
D86.0 Sarcoidosis of lung	0.000	0.996	0.004
K74.4 Secondary biliary cirrhosis	0.000	0.996	0.003
K74.2 Hepatic fibrosis with hepatic sclerosis	0.000	0.996	0.003
K76.5 Hepatic veno-occlusive disease	0.000	0.997	0.003
K76.4 Peliosis hepatis	0.000	0.997	0.003
K76.3 Infarction of liver	0.000	0.997	0.003
K76.2 Central haemorrhagic necrosis of liver	0.000	0.997	0.003
D51.3 Other dietary vitamin B12 deficiency anaemia	0.000	0.997	0.003
D51.2 Transcobalamin II deficiency	0.000	0.997	0.003
D51.1 Vitamin B12 deficiency anaemia due to selective vitamin B12 malabsorption with proteinuria	0.000	0.997	0.003
D86.1 Sarcoidosis of lymph nodes	0.000	0.997	0.003
J69.1 Pneumonitis due to oils and essences	0.000	0.997	0.003
C16 Malignant neoplasm of stomach	0.003	0.997	0.000
E24 Cushing's syndrome	0.003	0.997	0.000
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes	0.000	0.997	0.003
C16.2 Body of stomach	0.003	0.997	0.000
D80.1 Nonfamilial hypogammaglobulinaemia	0.000	0.997	0.003
D80.4 Selective deficiency of immunoglobulin M [IgM]	0.000	0.997	0.003
C16.3 Pyloric antrum	0.003	0.997	0.000
D86.3 Sarcoidosis of skin	0.000	0.997	0.003
K74.5 Biliary cirrhosis, unspecified	0.000	0.997	0.003
D51.8 Other vitamin B12 deficiency anaemias	0.000	0.997	0.003
D50.8 Other iron deficiency anaemias	0.000	0.997	0.003
D80.9 Immunodeficiency with predominantly antibody defects, unspecified	0.000	0.997	0.003
D80.8 Other immunodeficiencies with predominantly antibody defects	0.000	0.997	0.003
D80.7 Transient hypogammaglobulinaemia of infancy	0.000	0.997	0.003
D80.6 Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinaemia	0.000	0.997	0.003
D80.5 Immunodeficiency with increased immunoglobulin M [IgM]	0.000	0.997	0.003
D80.0 Hereditary hypogammaglobulinaemia	0.000	0.997	0.003
K75.8 Other specified inflammatory liver diseases	0.001	0.997	0.002
D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses	0.000	0.997	0.003
J69.8 Pneumonitis due to other solids and liquids	0.000	0.997	0.003
D72 Other disorders of white blood cells	0.000	0.997	0.003
D86.8 Sarcoidosis of other and combined sites	0.000	0.997	0.003
D81 Combined immunodeficiencies	0.000	0.997	0.003
J91 Pleural effusion in conditions classified elsewhere	0.000	0.997	0.003
J90-J94 Other diseases of pleura	0.000	0.997	0.003
K82.0 Obstruction of gallbladder	0.003	0.997	0.000
I34.1 Mitral (valve) prolapse	0.003	0.997	0.000
A49.0 Staphylococcal infection, unspecified	0.000	0.997	0.003
K74.1 Hepatic sclerosis	0.000	0.997	0.003
C16.5 Lesser curvature of stomach, unspecified	0.003	0.997	0.000
D53.8 Other specified nutritional anaemias	0.000	0.997	0.003
D53.2 Scorbutic anaemia	0.000	0.997	0.003
D53.0 Protein deficiency anaemia	0.000	0.997	0.003
K82.2 Perforation of gallbladder	0.003	0.997	0.000
C16.6 Greater curvature of stomach, unspecified	0.003	0.997	0.000
D82 Immunodeficiency associated with other major defects	0.000	0.997	0.003
D83 Common variable immunodeficiency	0.000	0.997	0.003
J60-J70 Lung diseases due to external agents	0.000	0.997	0.003
K76.6 Portal hypertension	0.000	0.997	0.003
D84 Other immunodeficiencies	0.000	0.997	0.003
T51.9 Alcohol, unspecified	0.000	0.997	0.003
D53.1 Other megaloblastic anaemias, not elsewhere classified	0.000	0.997	0.002
C16.8 Overlapping lesion of stomach	0.003	0.997	0.000
E24.8 Other Cushing's syndrome	0.003	0.997	0.000
E24.4 Alcohol-induced pseudo-Cushing's syndrome	0.003	0.997	0.000
E24.3 Ectopic ACTH syndrome	0.003	0.997	0.000
E24.1 Nelson's syndrome	0.003	0.997	0.000
J70.1 Chronic and other pulmonary manifestations due to radiation	0.000	0.997	0.003
D55-D59 Haemolytic anaemias	0.000	0.997	0.003
J70 Respiratory conditions due to other external agents	0.000	0.997	0.003
D53.9 Nutritional anaemia, unspecified	0.000	0.997	0.002
K76.7 Hepatorenal syndrome	0.000	0.997	0.002
M22.4 Chondromalacia patellae	0.003	0.997	0.000
I49.3 Ventricular premature depolarisation	0.000	0.997	0.003
J61 Pneumoconiosis due to asbestos and other mineral fibres	0.000	0.997	0.003
E24.2 Drug-induced Cushing's syndrome	0.002	0.997	0.000
J60 Coalworker's pneumoconiosis	0.000	0.997	0.002
C16.4 Pylorus	0.002	0.997	0.000
D72.9 Disorder of white blood cells, unspecified	0.000	0.997	0.002
D72.0 Genetic anomalies of leukocytes	0.000	0.997	0.002
D76.3 Other histiocytosis syndromes	0.001	0.997	0.002
K82.1 Hydrops of gallbladder	0.002	0.997	0.000
X62.9 Unspecified place	0.000	0.997	0.002
C16.1 Fundus of stomach	0.002	0.998	0.000
D81.9 Combined immunodeficiency, unspecified	0.000	0.998	0.002
D81.8 Other combined immunodeficiencies	0.000	0.998	0.002
D81.7 Major histocompatibility complex class II deficiency	0.000	0.998	0.002
D81.6 Major histocompatibility complex class I deficiency	0.000	0.998	0.002
D81.5 Purine nucleoside phosphorylase [PNP] deficiency	0.000	0.998	0.002
D81.4 Nezelof's syndrome	0.000	0.998	0.002
D81.3 Adenosine deaminase [ADA] deficiency	0.000	0.998	0.002
D81.2 Severe combined immunodeficiency [SCID] with low or normal B-cell numbers	0.000	0.998	0.002
D81.1 Severe combined immunodeficiency [SCID] with low T- and B-cell numbers	0.000	0.998	0.002
D81.0 Severe combined immunodeficiency [SCID] with reticular dysgenesis	0.000	0.998	0.002
T17 Foreign body in respiratory tract	0.000	0.998	0.002
M31.9 Necrotising vasculopathy, unspecified	0.002	0.998	0.000
T17.8 Foreign body in other and multiple parts of respiratory tract	0.000	0.998	0.002
M22.3 Other derangements of patella	0.002	0.998	0.000
D82.9 Immunodeficiency associated with major defect, unspecified	0.000	0.998	0.002
D82.8 Immunodeficiency associated with other specified major defects	0.000	0.998	0.002
D82.4 Hyperimmunoglobulin E [IgE] syndrome	0.000	0.998	0.002
D82.3 Immunodeficiency following hereditary defective response to Epstein-Barr virus	0.000	0.998	0.002
D82.2 Immunodeficiency with short-limbed stature	0.000	0.998	0.002
D82.0 Wiskott-Aldrich syndrome	0.000	0.998	0.002
M31.8 Other specified necrotising vasculopathies	0.002	0.998	0.000
D83.8 Other common variable immunodeficiencies	0.000	0.998	0.002
D83.2 Common variable immunodeficiency with autoantibodies to B- or T-cells	0.000	0.998	0.002
D83.1 Common variable immunodeficiency with predominant immunoregulatory T-cell disorders	0.000	0.998	0.002
D83.0 Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function	0.000	0.998	0.002
J68 Respiratory conditions due to inhalation of chemicals, gases, fumes and vapours	0.000	0.998	0.002
J66 Airway disease due to specific organic dust	0.000	0.998	0.002
J63 Pneumoconiosis due to other inorganic dusts	0.000	0.998	0.002
J62 Pneumoconiosis due to dust containing silica	0.000	0.998	0.002
J65 Pneumoconiosis associated with tuberculosis	0.000	0.998	0.002
M23.89 Other internal derangements of knee (Unspecified ligament or Unspecified meniscus)	0.002	0.998	0.000
D22.4 Melanocytic naevi of scalp and neck	0.000	0.998	0.002
K82.8 Other specified diseases of gallbladder	0.002	0.998	0.000
D73.0 Hyposplenism	0.000	0.998	0.002
D58.0 Hereditary spherocytosis	0.000	0.998	0.002
D84.0 Lymphocyte function antigen-1 [LFA-1] defect	0.000	0.998	0.002
H54.0 Blindness, both eyes	0.002	0.998	0.000
Z39.1 Care and examination of lactating mother	0.000	0.998	0.002
M31 Other necrotising vasculopathies	0.002	0.998	0.000
D58 Other hereditary haemolytic anaemias	0.000	0.998	0.002
K09.0 Developmental odontogenic cysts	0.002	0.998	0.000
D84.8 Other specified immunodeficiencies	0.000	0.998	0.002
D84.1 Defects in the complement system	0.000	0.998	0.002
K74.0 Hepatic fibrosis	0.000	0.998	0.002
D57 Sickle-cell disorders	0.000	0.998	0.002
D55 Anaemia due to enzyme disorders	0.000	0.998	0.002
J94 Other pleural conditions	0.000	0.998	0.002
S62.00 Fracture of navicular [scaphoid] bone of hand (closed)	0.000	0.998	0.002
D22.6 Melanocytic naevi of upper limb, including shoulder	0.000	0.998	0.002
D82.1 Di George's syndrome	0.000	0.998	0.002
J70.9 Respiratory conditions due to unspecified external agent	0.000	0.998	0.002
J70.8 Respiratory conditions due to other specified external agents	0.000	0.998	0.002
J70.3 Chronic drug-induced interstitial lung disorders	0.000	0.998	0.002
J70.2 Acute drug-induced interstitial lung disorders	0.000	0.998	0.002
T17.5 Foreign body in bronchus	0.000	0.998	0.002
J64 Unspecified pneumoconiosis	0.000	0.998	0.002
L73.2 Hidradenitis suppurativa	0.000	0.998	0.002
F02.0 Dementia in Pick's disease	0.002	0.998	0.000
J67 Hypersensitivity pneumonitis due to organic dust	0.000	0.998	0.002
M19.17 Post-traumatic arthrosis of other joints (Ankle and foot)	0.000	0.998	0.002
D12.4 Descending colon	0.002	0.998	0.000
D83.9 Common variable immunodeficiency, unspecified	0.000	0.998	0.002
J70.0 Acute pulmonary manifestations due to radiation	0.000	0.998	0.002
M31.5 Giant cell arteritis with polymyalgia rheumatica	0.002	0.998	0.000
D56 Thalassaemia	0.000	0.998	0.002
M43.09 Spondylolysis (Site unspecified)	0.000	0.998	0.002
D84.9 Immunodeficiency, unspecified	0.000	0.998	0.002
J70.4 Drug-induced interstitial lung disorder, unspecified	0.000	0.998	0.002
T17.3 Foreign body in larynx	0.000	0.998	0.002
K76.8 Other specified diseases of liver	0.000	0.998	0.002
T17.4 Foreign body in trachea	0.000	0.998	0.002
T17.1 Foreign body in nostril	0.000	0.998	0.002
T17.0 Foreign body in nasal sinus	0.000	0.998	0.002
V23.4 Driver injured in traffic accident	0.000	0.998	0.002
S90 Superficial injury of ankle and foot	0.002	0.998	0.000
D12.6 Colon, unspecified	0.000	0.998	0.002
L05 Pilonidal cyst	0.002	0.998	0.000
F02.3 Dementia in Parkinson's disease	0.002	0.998	0.000
J94.1 Fibrothorax	0.000	0.998	0.002
S90.8 Other superficial injuries of ankle and foot	0.002	0.998	0.000
J62.8 Pneumoconiosis due to other dust containing silica	0.000	0.998	0.002
J62.0 Pneumoconiosis due to talc dust	0.000	0.998	0.002
J63.8 Pneumoconiosis due to other specified inorganic dusts	0.000	0.998	0.002
J63.5 Stannosis	0.000	0.998	0.002
J63.4 Siderosis	0.000	0.998	0.002
J63.3 Graphite fibrosis (of lung)	0.000	0.998	0.002
J63.2 Berylliosis	0.000	0.998	0.002
J63.1 Bauxite fibrosis (of lung)	0.000	0.998	0.002
J63.0 Aluminosis (of lung)	0.000	0.998	0.002
J66.8 Airway disease due to other specific organic dusts	0.000	0.998	0.002
J66.2 Cannabinosis	0.000	0.998	0.002
J66.1 Flax-dresser's disease	0.000	0.998	0.002
J66.0 Byssinosis	0.000	0.998	0.002
J68.9 Unspecified respiratory condition due to chemicals, gases, fumes and vapours	0.000	0.998	0.002
J68.8 Other respiratory conditions due to chemicals, gases, fumes and vapours	0.000	0.998	0.002
J68.4 Chronic respiratory conditions due to chemicals, gases, fumes and vapours	0.000	0.998	0.002
J68.3 Other acute and subacute respiratory conditions due to chemicals, gases, fumes and vapours	0.000	0.998	0.002
J68.2 Upper respiratory inflammation due to chemicals, gases, fumes and vapours, not elsewhere classified	0.000	0.998	0.002
J68.1 Acute pulmonary oedema due to chemicals, gases, fumes and vapours	0.000	0.998	0.002
J68.0 Bronchitis and pneumonitis due to chemicals, gases, fumes and vapours	0.000	0.998	0.002
J94.8 Other specified pleural conditions	0.000	0.998	0.002
M31.2 Lethal midline granuloma	0.002	0.998	0.000
D75 Other diseases of blood and blood-forming organs	0.000	0.998	0.002
D58.8 Other specified hereditary haemolytic anaemias	0.000	0.998	0.002
D58.1 Hereditary elliptocytosis	0.000	0.998	0.002
M31.4 Aortic arch syndrome [Takayasu]	0.002	0.998	0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.001	0.998	0.001
D55.9 Anaemia due to enzyme disorder, unspecified	0.000	0.998	0.002
D55.8 Other anaemias due to enzyme disorders	0.000	0.998	0.002
D55.3 Anaemia due to disorders of nucleotide metabolism	0.000	0.998	0.002
D55.2 Anaemia due to disorders of glycolytic enzymes	0.000	0.998	0.002
D55.1 Anaemia due to other disorders of glutathione metabolism	0.000	0.998	0.002
D55.0 Anaemia due to glucose-6-phosphate dehydrogenase [G6PD] deficiency	0.000	0.998	0.002
D57.8 Other sickle-cell disorders	0.000	0.998	0.002
D57.3 Sickle-cell trait	0.000	0.998	0.002
D57.2 Double heterozygous sickling disorders	0.000	0.998	0.002
D57.1 Sickle-cell anaemia without crisis	0.000	0.998	0.002
D57.0 Sickle-cell anaemia with crisis	0.000	0.998	0.002
D72.1 Eosinophilia	0.000	0.998	0.002
J94.9 Pleural condition, unspecified	0.000	0.998	0.002
J94.0 Chylous effusion	0.000	0.998	0.002
O86.0 Infection of obstetric surgical wound	0.002	0.998	0.000
D22.9 Melanocytic naevi, unspecified	0.000	0.998	0.002
E78.8 Other disorders of lipoprotein metabolism	0.002	0.998	0.000
M31.1 Thrombotic microangiopathy	0.002	0.998	0.000
F33.3 Recurrent depressive disorder, current episode severe with psychotic symptoms	0.002	0.998	0.000
D89.1 Cryoglobulinaemia	0.001	0.998	0.000
J67.8 Hypersensitivity pneumonitis due to other organic dusts	0.000	0.998	0.002
J67.7 Air-conditioner and humidifier lung	0.000	0.998	0.002
J67.6 Maple-bark-stripper's lung	0.000	0.998	0.002
J67.5 Mushroom-worker's lung	0.000	0.998	0.002
J67.4 Maltworker's lung	0.000	0.998	0.002
J67.3 Suberosis	0.000	0.998	0.002
J67.1 Bagassosis	0.000	0.998	0.002
J67.0 Farmer's lung	0.000	0.998	0.002
M31.7 Microscopic polyangiitis	0.002	0.998	0.000
M43.0 Spondylolysis	0.000	0.998	0.002
J15.7 Pneumonia due to Mycoplasma pneumoniae	0.000	0.998	0.002
D56.9 Thalassaemia, unspecified	0.000	0.998	0.001
D56.8 Other thalassaemias	0.000	0.998	0.001
D56.4 Hereditary persistence of foetal haemoglobin [HPFH]	0.000	0.998	0.001
D56.3 Thalassaemia trait	0.000	0.998	0.002
D56.2 Delta-beta thalassaemia	0.000	0.998	0.001
D56.0 Alpha thalassaemia	0.000	0.998	0.001
J15.2 Pneumonia due to staphylococcus	0.000	0.998	0.002
S31.0 Open wound of lower back and pelvis	0.002	0.998	0.000
D04.6 Skin of upper limb, including shoulder	0.000	0.998	0.002
D26.0 Cervix uteri	0.000	0.998	0.002
H11.3 Conjunctival haemorrhage	0.000	0.998	0.002
H83.0 Labyrinthitis	0.000	0.998	0.002
M31.0 Hypersensitivity angiitis	0.002	0.998	0.000
M54.57 Low back pain (Lumbosacral region)	0.000	0.998	0.002
D58.2 Other haemoglobinopathies	0.000	0.998	0.001
J67.2 Bird fancier's lung	0.000	0.998	0.002
S90.7 Multiple superficial injuries of ankle and foot	0.002	0.998	0.000
S90.2 Contusion of toe(s) with damage to nail	0.002	0.998	0.000
M43.1 Spondylolisthesis	0.000	0.998	0.002
D68.5 Primary Thrombophilia	0.000	0.998	0.002
S90.0 Contusion of ankle	0.002	0.998	0.000
D58.9 Hereditary haemolytic anaemia, unspecified	0.000	0.998	0.001
M22 Disorders of patella	0.002	0.998	0.000
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified	0.001	0.998	0.001
S90.1 Contusion of toe(s) without damage to nail	0.001	0.998	0.000
F02 Dementia in other diseases classified elsewhere	0.002	0.998	0.000
M43.02 Spondylolysis (Cervical region)	0.000	0.998	0.002
D75.2 Essential thrombocytosis	0.000	0.998	0.001
H54.4 Blindness, one eye	0.002	0.998	0.000
J15.6 Pneumonia due to other aerobic Gram-negative bacteria	0.000	0.998	0.002
K51.0 Ulcerative (chronic) enterocolitis	0.000	0.998	0.002
S30.8 Other superficial injuries of abdomen, lower back and pelvis	0.000	0.998	0.002
D59 Acquired haemolytic anaemia	0.000	0.998	0.001
S06.50 Traumatic subdural haemorrhage (without open intracranial wound)	0.002	0.998	0.000
B97.8 Other viral agents as the cause of diseases classified to other chapters	0.000	0.998	0.002
F17.2 Dependence syndrome	0.002	0.998	0.000
J15.9 Bacterial pneumonia, unspecified	0.000	0.998	0.002
R23.3 Spontaneous ecchymoses	0.000	0.998	0.002
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.000	0.998	0.002
D89.3 Immune reconstitution syndrome	0.001	0.998	0.001
I80.0 Phlebitis and thrombophlebitis of superficial vessels of lower extremities	0.000	0.998	0.002
J67.9 Hypersensitivity pneumonitis due to unspecified organic dust	0.000	0.998	0.001
D65 Disseminated intravascular coagulation [defibrination syndrome]	0.000	0.998	0.002
D56.1 Beta thalassaemia	0.000	0.998	0.001
J15 Bacterial pneumonia, not elsewhere classified	0.000	0.998	0.002
Y43.3 Other antineoplastic drugs	0.000	0.998	0.002
M43.08 Spondylolysis (Sacral and sacrococcygeal region)	0.000	0.998	0.001
M43.07 Spondylolysis (Lumbosacral region)	0.000	0.998	0.001
M43.06 Spondylolysis (Lumbar region)	0.000	0.998	0.001
M43.05 Spondylolysis (Thoracolumbar region)	0.000	0.998	0.001
M43.04 Spondylolysis (Thoracic region)	0.000	0.998	0.001
M43.03 Spondylolysis (Cervicothoracic region)	0.000	0.998	0.001
M43.01 Spondylolysis (Occipito-atlanto-axial region)	0.000	0.998	0.001
M43.00 Spondylolysis (Multiple sites in spine)	0.000	0.998	0.001
M86.97 Osteomyelitis, unspecified (Ankle and foot)	0.002	0.998	0.000
V49.9 Car occupant [any] injured in unspecified traffic accident	0.000	0.998	0.002
C92.0 Acute myeloid leukaemia	0.000	0.998	0.002
D26.9 Uterus, unspecified	0.000	0.998	0.002
D75.0 Familial erythrocytosis	0.000	0.998	0.001
D89.9 Disorder involving the immune mechanism, unspecified	0.001	0.998	0.001
D89.0 Polyclonal hypergammaglobulinaemia	0.001	0.998	0.001
C49.0 Connective and soft tissue of head, face and neck	0.000	0.998	0.001
K74.6 Other and unspecified cirrhosis of liver	0.000	0.998	0.001
M22.2 Patellofemoral disorders	0.001	0.998	0.000
T88.4 Failed or difficult intubation	0.000	0.998	0.002
V43.9 Unspecified car occupant injured in traffic accident	0.000	0.998	0.001
M43.18 Spondylolisthesis (Sacral and sacrococcygeal region)	0.000	0.998	0.001
M43.15 Spondylolisthesis (Thoracolumbar region)	0.000	0.998	0.001
M43.14 Spondylolisthesis (Thoracic region)	0.000	0.998	0.001
M43.13 Spondylolisthesis (Cervicothoracic region)	0.000	0.998	0.001
M43.11 Spondylolisthesis (Occipito-atlanto-axial region)	0.000	0.998	0.001
M43.10 Spondylolisthesis (Multiple sites in spine)	0.000	0.998	0.001
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts	0.000	0.998	0.002
M43.19 Spondylolisthesis (Site unspecified)	0.000	0.999	0.001
J15.4 Pneumonia due to other streptococci	0.000	0.999	0.001
K74.3 Primary biliary cirrhosis	0.000	0.999	0.001
M22.1 Recurrent subluxation of patella	0.001	0.999	0.000
S31.7 Multiple open wounds of abdomen, lower back and pelvis	0.001	0.999	0.000
D59.8 Other acquired haemolytic anaemias	0.000	0.999	0.001
D59.6 Haemoglobinuria due to haemolysis from other external causes	0.000	0.999	0.001
D59.5 Paroxysmal nocturnal haemoglobinuria [Marchiafava-Micheli]	0.000	0.999	0.001
D59.3 Haemolytic-uraemic syndrome	0.000	0.999	0.001
D59.2 Drug-induced nonautoimmune haemolytic anaemia	0.000	0.999	0.001
D59.0 Drug-induced autoimmune haemolytic anaemia	0.000	0.999	0.001
F02.4 Dementia in human immunodeficiency virus [HIV] disease	0.001	0.999	0.000
F02.2 Dementia in Huntington's disease	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations