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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs485186
log Bayes Factor = 18.7474
Chromosome 19   position 49,207,206  (GRCh37) Explore rs485186 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
K80.1 Calculus of gallbladder with other cholecystitis
0.000 0.000 1.000
K80 Cholelithiasis
0.000 0.000 1.000
K80.2 Calculus of gallbladder without cholecystitis
0.000 0.000 1.000
K80.0 Calculus of gallbladder with acute cholecystitis
0.000 0.000 1.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.000 0.000 1.000
K26.9 Unspecified as acute or chronic, without haemorrhage or perforation
0.000 0.000 1.000
K26 Duodenal ulcer
0.000 0.001 0.999
K29 Gastritis and duodenitis
0.000 0.001 0.999
K20-K31 Diseases of oesophagus, stomach and duodenum
0.000 0.001 0.999
I10 Essential (primary) hypertension
0.000 0.002 0.998
K29.8 Duodenitis
0.000 0.002 0.998
K82 Other diseases of gallbladder
0.000 0.004 0.996
Chapter XI Diseases of the digestive system
0.000 0.005 0.995
K82.4 Cholesterolosis of gallbladder
0.000 0.018 0.982
K29.0 Acute haemorrhagic gastritis
0.000 0.024 0.976
K65-K67 Diseases of peritoneum
0.000 0.040 0.960
K82.8 Other specified diseases of gallbladder
0.000 0.046 0.954
K83 Other diseases of biliary tract
0.000 0.048 0.952
K83.1 Obstruction of bile duct
0.000 0.065 0.935
K31 Other diseases of stomach and duodenum
0.000 0.080 0.920
K29.5 Chronic gastritis, unspecified
0.000 0.084 0.916
K66 Other disorders of peritoneum
0.000 0.091 0.909
K29.4 Chronic atrophic gastritis
0.000 0.098 0.902
E78.0 Pure hypercholesterolaemia
0.000 0.099 0.901
K31.8 Other specified diseases of stomach and duodenum
0.000 0.106 0.894
K82.9 Disease of gallbladder, unspecified
0.000 0.107 0.893
K83.0 Cholangitis
0.000 0.115 0.885
I80.2 Phlebitis and thrombophlebitis of other deep vessels of lower extremities
0.000 0.124 0.876
I83.9 Varicose veins of lower extremities without ulcer or inflammation
0.000 0.125 0.875
I83 Varicose veins of lower extremities
0.000 0.129 0.871
I80 Phlebitis and thrombophlebitis
0.000 0.132 0.868
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.000 0.134 0.866
K66.0 Peritoneal adhesions
0.000 0.135 0.865
K65 Peritonitis
0.000 0.170 0.830
K66.8 Other specified disorders of peritoneum
0.000 0.181 0.819
I83.0 Varicose veins of lower extremities with ulcer
0.000 0.185 0.815
K26.6 Chronic or unspecified with both haemorrhage and perforation
0.000 0.187 0.813
K26.4 Chronic or unspecified with haemorrhage
0.000 0.188 0.812
K31.9 Disease of stomach and duodenum, unspecified
0.000 0.189 0.811
I10-I15 Hypertensive diseases
0.000 0.191 0.809
K26.1 Acute with perforation
0.000 0.203 0.797
K80.5 Calculus of bile duct without cholangitis or cholecystitis
0.000 0.203 0.797
K26.7 Chronic without haemorrhage or perforation
0.000 0.209 0.791
K29.2 Alcoholic gastritis
0.000 0.216 0.784
Chapter IX Diseases of the circulatory system
0.000 0.233 0.767
K29.3 Chronic superficial gastritis
0.000 0.235 0.765
K26.2 Acute with both haemorrhage and perforation
0.000 0.240 0.760
I85 Oesophageal varices
0.000 0.246 0.754
K23 Disorders of oesophagus in diseases classified elsewhere
0.000 0.247 0.753
K65.8 Other peritonitis
0.000 0.248 0.752
K27 Peptic ulcer, site unspecified
0.000 0.251 0.749
K70-K77 Diseases of liver
0.000 0.257 0.743
K31.4 Gastric diverticulum
0.000 0.273 0.727
I80.0 Phlebitis and thrombophlebitis of superficial vessels of lower extremities
0.000 0.275 0.725
K80.3 Calculus of bile duct with cholangitis
0.000 0.283 0.717
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere
0.000 0.283 0.717
K29.9 Gastroduodenitis, unspecified
0.000 0.283 0.716
I88 Nonspecific lymphadenitis
0.000 0.293 0.707
K80.8 Other cholelithiasis
0.000 0.295 0.705
K31.2 Hourglass stricture and stenosis of stomach
0.000 0.301 0.699
K70 Alcoholic liver disease
0.000 0.309 0.691
K67 Disorders of peritoneum in infectious diseases classified elsewhere
0.000 0.311 0.688
K83.5 Biliary cyst
0.000 0.317 0.682
I85.9 Oesophageal varices without bleeding
0.000 0.323 0.677
K70.3 Alcoholic cirrhosis of liver
0.000 0.323 0.677
K83.9 Disease of biliary tract, unspecified
0.000 0.326 0.674
K82.3 Fistula of gallbladder
0.000 0.327 0.673
K26.0 Acute with haemorrhage
0.000 0.328 0.672
K28 Gastrojejunal ulcer
0.000 0.328 0.672
K66.9 Disorder of peritoneum, unspecified
0.000 0.329 0.671
K31.3 Pylorospasm, not elsewhere classified
0.000 0.332 0.668
I83.2 Varicose veins of lower extremities with both ulcer and inflammation
0.000 0.337 0.663
K31.0 Acute dilatation of stomach
0.000 0.339 0.661
I80.9 Phlebitis and thrombophlebitis of unspecified site
0.000 0.345 0.655
K73 Chronic hepatitis, not elsewhere classified
0.000 0.357 0.643
K27.7 Chronic without haemorrhage or perforation
0.000 0.357 0.643
K50-K52 Noninfective enteritis and colitis
0.000 0.358 0.642
K31.1 Adult hypertrophic pyloric stenosis
0.000 0.369 0.631
K90-K93 Other diseases of the digestive system
0.000 0.370 0.630
K25 Gastric ulcer
0.000 0.381 0.619
I70-I79 Diseases of arteries, arterioles and capillaries
0.000 0.384 0.616
K50 Crohn's disease [regional enteritis]
0.000 0.388 0.612
K82.2 Perforation of gallbladder
0.000 0.391 0.609
I88.9 Nonspecific lymphadenitis, unspecified
0.000 0.397 0.603
I82 Other venous embolism and thrombosis
0.000 0.398 0.602
I80.8 Phlebitis and thrombophlebitis of other sites
0.000 0.398 0.602
K50.1 Crohn's disease of large intestine
0.000 0.399 0.601
K83.2 Perforation of bile duct
0.000 0.403 0.597
K91 Postprocedural disorders of digestive system, not elsewhere classified
0.000 0.403 0.597
I15 Secondary hypertension
0.000 0.408 0.592
K82.0 Obstruction of gallbladder
0.000 0.412 0.587
K31.6 Fistula of stomach and duodenum
0.000 0.413 0.587
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.000 0.414 0.586
K65.0 Acute peritonitis
0.000 0.414 0.586
I13 Hypertensive heart and renal disease
0.000 0.420 0.580
K23.8 Disorders of oesophagus in other diseases classified elsewhere
0.000 0.423 0.576
I71 Aortic aneurysm and dissection
0.000 0.431 0.569
K26.5 Chronic or unspecified with perforation
0.000 0.438 0.562
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.000 0.439 0.561
K25.3 Acute without haemorrhage or perforation
0.000 0.439 0.561
K65.9 Peritonitis, unspecified
0.000 0.441 0.559
K82.1 Hydrops of gallbladder
0.000 0.444 0.556
K74 Fibrosis and cirrhosis of liver
0.000 0.448 0.552
I87 Other disorders of veins
0.000 0.450 0.550
K83.3 Fistula of bile duct
0.000 0.452 0.548
K70.2 Alcoholic fibrosis and sclerosis of liver
0.000 0.457 0.543
K91.0 Vomiting following gastro-intestinal surgery
0.000 0.458 0.542
K23.1 Megaoesophagus in Chagas' disease
0.000 0.460 0.540
K23.0 Tuberculous oesophagitis
0.000 0.460 0.540
K73.9 Chronic hepatitis, unspecified
0.000 0.461 0.539
K27.6 Chronic or unspecified with both haemorrhage and perforation
0.000 0.463 0.537
K27.5 Chronic or unspecified with perforation
0.000 0.463 0.537
K27.4 Chronic or unspecified with haemorrhage
0.000 0.463 0.537
K27.2 Acute with both haemorrhage and perforation
0.000 0.463 0.537
K27.1 Acute with perforation
0.000 0.463 0.537
K27.0 Acute with haemorrhage
0.000 0.463 0.537
I72 Other aneurysm
0.000 0.467 0.533
I80.3 Phlebitis and thrombophlebitis of lower extremities, unspecified
0.000 0.467 0.533
K77 Liver disorders in diseases classified elsewhere
0.000 0.467 0.532
I85.0 Oesophageal varices with bleeding
0.000 0.468 0.532
K26.3 Acute without haemorrhage or perforation
0.000 0.473 0.527
K83.4 Spasm of sphincter of Oddi
0.000 0.476 0.524
K91.8 Other postprocedural disorders of digestive system, not elsewhere classified
0.000 0.480 0.520
I88.8 Other nonspecific lymphadenitis
0.000 0.485 0.515
K80.36 Calculus of bile duct with acute and chronic cholangitis without obstruction
0.000 0.486 0.514
K87.1 Disorders of pancreas in diseases classified elsewhere
0.000 0.486 0.514
K87.0 Disorders of gallbladder and biliary tract in diseases classified elsewhere
0.000 0.486 0.514
I28 Other diseases of pulmonary vessels
0.000 0.487 0.513
I88.1 Chronic lymphadenitis, except mesenteric
0.000 0.493 0.507
I00-I02 Acute rheumatic fever
0.000 0.496 0.504
K73.8 Other chronic hepatitis, not elsewhere classified
0.000 0.499 0.501
I74 Arterial embolism and thrombosis
0.000 0.499 0.501
K27.3 Acute without haemorrhage or perforation
0.000 0.504 0.496
K70.9 Alcoholic liver disease, unspecified
0.000 0.505 0.495
I82.9 Embolism and thrombosis of unspecified vein
0.000 0.505 0.495
K25.5 Chronic or unspecified with perforation
0.000 0.506 0.494
K67.8 Other disorders of peritoneum in infectious diseases classified elsewhere
0.000 0.506 0.494
K67.3 Tuberculous peritonitis
0.000 0.506 0.494
K67.2 Syphilitic peritonitis
0.000 0.506 0.494
K67.1 Gonococcal peritonitis
0.000 0.506 0.494
K67.0 Chlamydial peritonitis
0.000 0.506 0.494
K91.3 Postoperative intestinal obstruction
0.000 0.507 0.493
I87.2 Venous insufficiency (chronic) (peripheral)
0.000 0.508 0.492
I15.9 Seconday hypertension, unspecified
0.000 0.510 0.490
I70 Atherosclerosis
0.000 0.511 0.489
I86 Varicose veins of other sites
0.000 0.511 0.488
K76 Other diseases of liver
0.000 0.514 0.486
K73.2 Chronic active hepatitis, not elsewhere classified
0.000 0.516 0.484
K28.7 Chronic without haemorrhage or perforation
0.000 0.518 0.482
K28.6 Chronic or unspecified with both haemorrhage and perforation
0.000 0.518 0.482
K28.5 Chronic or unspecified with perforation
0.000 0.518 0.482
K28.4 Chronic or unspecified with haemorrhage
0.000 0.518 0.482
K28.3 Acute without haemorrhage or perforation
0.000 0.518 0.482
K28.2 Acute with both haemorrhage and perforation
0.000 0.518 0.482
K28.1 Acute with perforation
0.000 0.518 0.482
K28.0 Acute with haemorrhage
0.000 0.518 0.482
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.000 0.520 0.480
I88.0 Nonspecific mesenteric lymphadenitis
0.000 0.521 0.479
K74.0 Hepatic fibrosis
0.000 0.524 0.476
K31.5 Obstruction of duodenum
0.000 0.524 0.476
I26 Pulmonary embolism
0.000 0.525 0.475
K91.4 Colostomy and enterostomy malfunction
0.000 0.530 0.470
I81 Portal vein thrombosis
0.000 0.533 0.467
K85 Acute pancreatitis
0.000 0.534 0.466
K73.1 Chronic lobular hepatitis, not elsewhere classified
0.000 0.539 0.461
K73.0 Chronic persistent hepatitis, not elsewhere classified
0.000 0.539 0.461
I72.4 Aneurysm of artery of lower extremity
0.000 0.539 0.461
I82.0 Budd-Chiari syndrome
0.000 0.540 0.460
I28.8 Other specified diseases of pulmonary vessels
0.000 0.541 0.459
I82.2 Embolism and thrombosis of vena cava
0.000 0.545 0.455
K25.7 Chronic without haemorrhage or perforation
0.000 0.547 0.453
K93 Disorders of other digestive organs in diseases classified elsewhere
0.000 0.548 0.452
K27.9 Unspecified as acute or chronic, without haemorrhage or perforation
0.000 0.550 0.450
K25.2 Acute with both haemorrhage and perforation
0.000 0.556 0.444
K25.1 Acute with perforation
0.000 0.556 0.444
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.000 0.558 0.442
K50.9 Crohn's disease, unspecified
0.000 0.559 0.441
I11 Hypertensive heart disease
0.000 0.561 0.439
K28.9 Unspecified as acute or chronic, without haemorrhage or perforation
0.000 0.563 0.437
K71 Toxic liver disease
0.000 0.563 0.436
I72.9 Aneurysm of unspecified site
0.000 0.565 0.435
I82.1 Thrombophlebitis migrans
0.000 0.568 0.431
K91.1 Postgastric surgery syndromes
0.000 0.570 0.430
K91.5 Postcholecystectomy syndrome
0.000 0.571 0.429
K29.1 Other acute gastritis
0.000 0.571 0.429
I70.0 Atherosclerosis of aorta
0.000 0.573 0.427
I15.8 Other secondary hypertension
0.000 0.575 0.425
I15.2 Hypertension secondary to endocrine disorders
0.000 0.575 0.425
K74.5 Biliary cirrhosis, unspecified
0.000 0.576 0.424
K50.8 Other Crohn's disease
0.000 0.580 0.420
K70.4 Alcoholic hepatic failure
0.000 0.583 0.417
I13.9 Hypertensive heart and renal disease, unspecified
0.000 0.584 0.416
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure
0.000 0.584 0.416
I13.1 Hypertensive heart and renal disease with renal failure
0.000 0.584 0.416
I13.0 Hypertensive heart and renal disease with (congestive) heart failure
0.000 0.584 0.416
K25.0 Acute with haemorrhage
0.000 0.585 0.415
I71.1 Thoracic aortic aneurysm, ruptured
0.000 0.585 0.415
K25.4 Chronic or unspecified with haemorrhage
0.000 0.585 0.415
K76.8 Other specified diseases of liver
0.000 0.586 0.414
I15.1 Hypertension secondary to other renal disorders
0.000 0.591 0.409
I74.5 Embolism and thrombosis of iliac artery
0.000 0.592 0.408
I71.8 Aortic aneurysm of unspecified site, ruptured
0.000 0.592 0.408
I71.5 Thoracoabdominal aortic aneurysm, ruptured
0.000 0.592 0.408
I72.0 Aneurysm of carotid artery
0.000 0.592 0.408
I72.2 Aneurysm of renal artery
0.000 0.593 0.407
I26.9 Pulmonary embolism without mention of acute cor pulmonale
0.000 0.593 0.407
I86.4 Gastric varices
0.000 0.600 0.400
K70.1 Alcoholic hepatitis
0.000 0.603 0.397
K74.4 Secondary biliary cirrhosis
0.000 0.604 0.396
K74.2 Hepatic fibrosis with hepatic sclerosis
0.000 0.604 0.396
K91.9 Postprocedural disorder of digestive system, unspecified
0.000 0.605 0.395
I87.0 Postphlebitic syndrome
0.000 0.606 0.394
K80.4 Calculus of bile duct with cholecystitis
0.000 0.606 0.394
K74.1 Hepatic sclerosis
0.000 0.606 0.393
I82.3 Embolism and thrombosis of renal vein
0.000 0.607 0.393
I77 Other disorders of arteries and arterioles
0.000 0.611 0.389
K70.0 Alcoholic fatty liver
0.000 0.612 0.388
I80.1 Phlebitis and thrombophlebitis of femoral vein
0.000 0.613 0.387
I74.1 Embolism and thrombosis of other and unspecified parts of aorta
0.000 0.614 0.386
I70.00 Atherosclerosis of aorta (without gangrene)
0.000 0.617 0.383
I72.6 Aneurysm and dissection of vertebral artery
0.000 0.618 0.382
I72.5 Aneurysm and dissection of other precerebral arteries
0.000 0.618 0.382
K77.8 Liver disorders in other diseases classified elsewhere
0.000 0.618 0.382
K77.0 Liver disorders in infectious and parasitic diseases classified elsewhere
0.000 0.618 0.382
K74.6 Other and unspecified cirrhosis of liver
0.000 0.620 0.380
I70.1 Atherosclerosis of renal artery
0.000 0.626 0.374
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture
0.000 0.628 0.372
K76.0 Fatty (change of) liver, not elsewhere classified
0.000 0.630 0.370
K72 Hepatic failure, not elsewhere classified
0.000 0.630 0.370
I28.9 Disease of pulmonary vessels, unspecified
0.000 0.631 0.368
I28.1 Aneurysm of pulmonary artery
0.000 0.632 0.367
I28.0 Arteriovenous fistula of pulmonary vessels
0.000 0.632 0.367
K85.8 Other acute pancreatitis
0.000 0.632 0.368
I89 Other non-infective disorders of lymphatic vessels and lymph nodes
0.000 0.638 0.361
I02 Rheumatic chorea
0.000 0.639 0.361
I01 Rheumatic fever with heart involvement
0.000 0.639 0.361
I15.0 Renovascular hypertension
0.000 0.639 0.361
I95-I99 Other and unspecified disorders of the circulatory system
0.000 0.641 0.359
I60-I69 Cerebrovascular diseases
0.000 0.643 0.357
I86.8 Varicose veins of other specified sites
0.000 0.643 0.357
I72.8 Aneurysm of other specified arteries
0.000 0.644 0.356
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.645 0.355
I71.3 Abdominal aortic aneurysm, ruptured
0.000 0.645 0.355
I87.9 Disorder of vein, unspecified
0.000 0.645 0.354
I74.9 Embolism and thrombosis of unspecified artery
0.000 0.648 0.352
I70.9 Generalised and unspecified atherosclerosis
0.000 0.650 0.350
I86.0 Sublingual varices
0.000 0.650 0.350
K76.5 Hepatic veno-occlusive disease
0.000 0.652 0.348
K76.4 Peliosis hepatis
0.000 0.652 0.348
K76.3 Infarction of liver
0.000 0.652 0.348
K76.2 Central haemorrhagic necrosis of liver
0.000 0.652 0.348
I77.8 Other specified disorders of arteries and arterioles
0.000 0.652 0.348
I72.1 Aneurysm of artery of upper extremity
0.000 0.653 0.347
K76.1 Chronic passive congestion of liver
0.000 0.653 0.347
I86.2 Pelvic varices
0.000 0.654 0.346
I72.3 Aneurysm of iliac artery
0.000 0.660 0.340
I61 Intracerebral haemorrhage
0.000 0.661 0.339
K25.6 Chronic or unspecified with both haemorrhage and perforation
0.000 0.664 0.336
K85.1 Biliary acute pancreatitis
0.000 0.673 0.327
I11.0 Hypertensive heart disease with (congestive) heart failure
0.000 0.674 0.326
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere
0.000 0.676 0.324
K93.1 Megacolon in Chagas' disease
0.000 0.676 0.324
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands
0.000 0.676 0.324
I86.3 Vulval varices
0.000 0.677 0.323
K76.7 Hepatorenal syndrome
0.000 0.677 0.323
K50.0 Crohn's disease of small intestine
0.000 0.677 0.323
I71.0 Dissection of aorta [any part]
0.000 0.680 0.320
I12 Hypertensive renal disease
0.000 0.681 0.319
I63 Cerebral infarction
0.000 0.681 0.319
I26.0 Pulmonary embolism with mention of acute cor pulmonale
0.000 0.682 0.318
I77.6 Arteritis, unspecified
0.000 0.682 0.318
K71.0 Toxic liver disease with cholestasis
0.000 0.683 0.316
I00 Rheumatic fever without mention of heart involvement
0.000 0.685 0.315
K76.6 Portal hypertension
0.000 0.687 0.313
K71.9 Toxic liver disease, unspecified
0.000 0.687 0.313
K71.8 Toxic liver disease with other disorders of liver
0.000 0.687 0.313
K71.7 Toxic liver disease with fibrosis and cirrhosis of liver
0.000 0.687 0.313
K71.5 Toxic liver disease with chronic active hepatitis
0.000 0.687 0.313
K71.4 Toxic liver disease with chronic lobular hepatitis
0.000 0.687 0.313
K71.3 Toxic liver disease with chronic persistent hepatitis
0.000 0.687 0.313
K71.2 Toxic liver disease with acute hepatitis
0.000 0.687 0.313
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries
0.000 0.687 0.313
K85.3 Drug-induced acute pancreatitis
0.000 0.692 0.308
I70.2 Atherosclerosis of arteries of the extremities
0.000 0.692 0.307
I98 Other disorders of circulatory system in diseases classified elsewhere
0.000 0.693 0.307
I70.01 Atherosclerosis of aorta (with gangrene)
0.000 0.694 0.306
K85.9 Acute pancreatitis, unspecified
0.000 0.699 0.301
I74.0 Embolism and thrombosis of abdominal aorta
0.000 0.699 0.300
K29.6 Other gastritis
0.000 0.700 0.300
I70.8 Atherosclerosis of other arteries
0.000 0.700 0.300
K91.2 Postsurgical malabsorption, not elsewhere classified
0.000 0.701 0.298
K85.0 Idiopathic acute pancreatitis
0.000 0.703 0.297
I70.10 Atherosclerosis of renal artery (without gangrene)
0.000 0.708 0.292
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.000 0.709 0.291
I61.5 Intracerebral haemorrhage, intraventricular
0.000 0.711 0.289
I87.1 Compression of vein
0.000 0.714 0.286
I74.4 Embolism and thrombosis of arteries of extremities, unspecified
0.000 0.715 0.285
I77.9 Disorder of arteries and arterioles, unspecified
0.000 0.718 0.282
I77.5 Necrosis of artery
0.000 0.721 0.279
I77.4 Coeliac artery compression syndrome
0.000 0.721 0.279
I61.3 Intracerebral haemorrhage in brain stem
0.000 0.722 0.278
I71.9 Aortic aneurysm of unspecified site, without mention of rupture
0.000 0.724 0.276
K71.1 Toxic liver disease with hepatic necrosis
0.000 0.726 0.273
I89.1 Lymphangitis
0.000 0.728 0.272
I61.4 Intracerebral haemorrhage in cerebellum
0.000 0.728 0.272
K83.8 Other specified diseases of biliary tract
0.000 0.730 0.270
I61.1 Intracerebral haemorrhage in hemisphere, cortical
0.000 0.730 0.270
I70.11 Atherosclerosis of renal artery (with gangrene)
0.000 0.731 0.268
I77.3 Arterial fibromuscular dysplasia
0.000 0.732 0.268
K71.6 Toxic liver disease with hepatitis, not elsewhere classified
0.000 0.735 0.265
I98.2 Oesophageal varices in diseases classified elsewhere
0.000 0.735 0.265
I61.8 Other intracerebral haemorrhage
0.000 0.737 0.263
I87.8 Other specified disorders of veins
0.000 0.739 0.261
I61.2 Intracerebral haemorrhage in hemisphere, unspecified
0.000 0.740 0.260
I01.9 Acute rheumatic heart disease, unspecified
0.000 0.741 0.259
I01.8 Other acute rheumatic heart disease
0.000 0.741 0.259
I01.2 Acute rheumatic myocarditis
0.000 0.741 0.259
I01.1 Acute rheumatic endocarditis
0.000 0.741 0.259
I01.0 Acute rheumatic pericarditis
0.000 0.741 0.259
I02.9 Rheumatic chorea without heart involvement
0.000 0.741 0.259
I02.0 Rheumatic chorea with heart involvement
0.000 0.741 0.259
I82.8 Embolism and thrombosis of other specified veins
0.000 0.743 0.257
I61.9 Intracerebral haemorrhage, unspecified
0.000 0.744 0.256
I79.1 Aortitis in diseases classified elsewhere
0.000 0.745 0.255
I79.0 Aneurysm of aorta in diseases classified elsewhere
0.000 0.745 0.255
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.000 0.747 0.253
I70.91 Generalized and unspecified atherosclerosis (with gangrene)
0.000 0.749 0.251
I70.90 Generalized and unspecified atherosclerosis (without gangrene)
0.000 0.749 0.251
K74.3 Primary biliary cirrhosis
0.000 0.751 0.249
I70.21 Atherosclerosis of arteries of extremities (with gangrene)
0.000 0.753 0.247
I60 Subarachnoid haemorrhage
0.000 0.753 0.247
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries
0.000 0.755 0.245
K35-K38 Diseases of appendix
0.000 0.755 0.245
I68 Cerebrovascular disorders in diseases classified elsewhere
0.000 0.758 0.242
K66.1 Haemoperitoneum
0.003 0.760 0.237
K72.9 Hepatic failure, unspecified
0.000 0.764 0.236
I63.0 Cerebral infarction due to thrombosis of precerebral arteries
0.000 0.766 0.234
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.000 0.771 0.229
K40-K46 Hernia
0.000 0.771 0.229
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic
0.000 0.771 0.229
I63.1 Cerebral infarction due to embolism of precerebral arteries
0.000 0.771 0.229
I98.3 Oesophageal varices with bleeding in diseases classified elsewhere
0.000 0.772 0.228
I61.6 Intracerebral haemorrhage, multiple localised
0.000 0.774 0.226
I73 Other peripheral vascular diseases
0.000 0.776 0.224
K72.0 Acute and subacute hepatic failure
0.000 0.776 0.224
I89.8 Other specified non-infective disorders of lymphatic vessels and lymph nodes
0.000 0.778 0.222
I65.3 Occlusion and stenosis of multiple and bilateral precerebral arteries
0.000 0.778 0.222
I77.0 Arteriovenous fistula, acquired
0.000 0.778 0.221
I98.8 Other specified disorders of circulatory system in diseases classified elsewhere
0.000 0.780 0.220
I98.1 Cardiovascular disorders in other infectious and parasitic diseases classified elsewhere
0.000 0.780 0.220
I98.0 Cardiovascular syphilis
0.000 0.780 0.220
I78 Diseases of capillaries
0.000 0.780 0.220
K72.1 Chronic hepatic failure
0.000 0.780 0.219
I61.0 Intracerebral haemorrhage in hemisphere, subcortical
0.000 0.781 0.219
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.000 0.781 0.218
I79.2 Peripheral angiopathy in diseases classified elsewhere
0.000 0.782 0.218
I60.9 Subarachnoid haemorrhage, unspecified
0.000 0.783 0.217
I70.81 Atherosclerosis of other arteries (with gangrene)
0.000 0.785 0.215
K52 Other non-infective gastro-enteritis and colitis
0.000 0.787 0.213
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation
0.000 0.787 0.213
K85.2 Alcohol-induced acute pancreatitis
0.001 0.788 0.212
I12.9 Hypertensive renal disease without renal failure
0.000 0.789 0.211
K76.9 Liver disease, unspecified
0.000 0.791 0.209
I89.0 Lymphoedema, not elsewhere classified
0.000 0.793 0.207
I63.3 Cerebral infarction due to thrombosis of cerebral arteries
0.000 0.795 0.205
I62 Other nontraumatic intracranial haemorrhage
0.000 0.795 0.205
I63.9 Cerebral infarction, unspecified
0.000 0.796 0.204
I77.2 Rupture of artery
0.000 0.796 0.204
K75 Other inflammatory liver diseases
0.000 0.799 0.200
K41 Femoral hernia
0.000 0.801 0.199
I69 Sequelae of cerebrovascular disease
0.000 0.801 0.199
I74.8 Embolism and thrombosis of other arteries
0.001 0.803 0.197
I65.1 Occlusion and stenosis of basilar artery
0.000 0.804 0.196
K41.3 Unilateral or unspecified femoral hernia, with obstruction, without gangrene
0.000 0.806 0.194
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.000 0.806 0.193
I60.3 Subarachnoid haemorrhage from posterior communicating artery
0.000 0.810 0.190
I60.4 Subarachnoid haemorrhage from basilar artery
0.000 0.814 0.186
I65.0 Occlusion and stenosis of vertebral artery
0.000 0.815 0.185
I99 Other and unspecified disorders of circulatory system
0.000 0.817 0.183
I83.1 Varicose veins of lower extremities with inflammation
0.000 0.818 0.182
K90 Intestinal malabsorption
0.000 0.818 0.182
I65.9 Occlusion and stenosis of unspecified precerebral artery
0.000 0.818 0.182
I65.8 Occlusion and stenosis of other precerebral artery
0.000 0.818 0.182
I69.3 Sequelae of cerebral infarction
0.000 0.819 0.181
K43 Ventral hernia
0.000 0.821 0.179
I66.4 Occlusion and stenosis of multiple and bilateral cerebral arteries
0.000 0.822 0.178
I60.5 Subarachnoid haemorrhage from vertebral artery
0.000 0.823 0.177
K75.0 Abscess of liver
0.000 0.826 0.174
I68.8 Other cerebrovascular disorders in diseases classified elsewhere
0.000 0.826 0.174
I68.2 Cerebral arteritis in other diseases classified elsewhere
0.000 0.826 0.174
I68.1 Cerebral arteritis in infectious and parasitic diseases classified elsewhere
0.000 0.826 0.174
K21 Gastro-oesophageal reflux disease
0.000 0.828 0.172
K52.3 Indeterminate colitis
0.000 0.829 0.171
I73.1 Thromboangiitis obliterans [Buerger]
0.000 0.830 0.170
I63.4 Cerebral infarction due to embolism of cerebral arteries
0.000 0.831 0.169
I05-I09 Chronic rheumatic heart diseases
0.000 0.831 0.169
I66.0 Occlusion and stenosis of middle cerebral artery
0.000 0.834 0.165
I70.80 Atherosclerosis of other arteries (without gangrene)
0.001 0.835 0.164
I66.8 Occlusion and stenosis of other cerebral artery
0.000 0.835 0.164
I66.2 Occlusion and stenosis of posterior cerebral artery
0.000 0.835 0.164
I66.1 Occlusion and stenosis of anterior cerebral artery
0.000 0.835 0.164
K46 Unspecified abdominal hernia
0.000 0.836 0.164
I73.8 Other specified peripheral vascular diseases
0.000 0.837 0.162
I89.9 Non-infective disorder of lymphatic vessels and lymph nodes, unspecified
0.000 0.838 0.162
I62.1 Nontraumatic extradural haemorrhage
0.000 0.838 0.162
I60.6 Subarachnoid haemorrhage from other intracranial arteries
0.000 0.839 0.161
I95 Hypotension
0.000 0.840 0.160
I68.0 Cerebral amyloid angiopathy
0.000 0.840 0.160
K43.9 Ventral hernia without obstruction or gangrene
0.000 0.843 0.157
I69.1 Sequelae of intracerebral haemorrhage
0.000 0.843 0.157
I78.8 Other diseases of capillaries
0.000 0.843 0.156
I97.2 Postmastectomy lymphoedema syndrome
0.000 0.844 0.156
K52.1 Toxic gastro-enteritis and colitis
0.000 0.844 0.156
K35 Acute appendicitis
0.000 0.847 0.153
I66.3 Occlusion and stenosis of cerebellar arteries
0.000 0.847 0.153
I63.8 Other cerebral infarction
0.000 0.847 0.153
I60.8 Other subarachnoid haemorrhage
0.000 0.847 0.153
K36 Other appendicitis
0.000 0.847 0.152
I27 Other pulmonary heart diseases
0.000 0.849 0.151
I78.9 Disease of capillaries, unspecified
0.000 0.849 0.151
I69.2 Sequelae of other nontraumatic intracranial haemorrhage
0.000 0.853 0.147
I11.9 Hypertensive heart disease without (congestive) heart failure
0.001 0.854 0.146
I77.1 Stricture of artery
0.000 0.854 0.146
K75.2 Nonspecific reactive hepatitis
0.000 0.856 0.144
K75.1 Phlebitis of portal vein
0.000 0.856 0.144
K52.8 Other specified non-infective gastro-enteritis and colitis
0.000 0.856 0.144
K41.1 Bilateral femoral hernia, with gangrene
0.000 0.857 0.143
K41.0 Bilateral femoral hernia, with obstruction, without gangrene
0.000 0.857 0.143
K41.4 Unilateral or unspecified femoral hernia, with gangrene
0.000 0.857 0.143
I95.2 Hypotension due to drugs
0.000 0.863 0.137
I78.0 Hereditary haemorrhagic telangiectasia
0.000 0.864 0.135
I60.1 Subarachnoid haemorrhage from middle cerebral artery
0.000 0.865 0.135
I97.0 Postcardiotomy syndrome
0.000 0.866 0.134
K52.2 Allergic and dietetic gastro-enteritis and colitis
0.000 0.867 0.133
K35.2 Acute appendicitis with generalized peritonitis
0.000 0.867 0.133
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.869 0.131
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified
0.000 0.869 0.131
I27.9 Pulmonary heart disease, unspecified
0.000 0.869 0.131
K90.3 Pancreatic steatorrhoea
0.000 0.869 0.131
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.869 0.131
K90.1 Tropical sprue
0.000 0.869 0.131
I60.2 Subarachnoid haemorrhage from anterior communicating artery
0.000 0.870 0.130
K52.0 Gastro-enteritis and colitis due to radiation
0.000 0.871 0.129
I86.1 Scrotal varices
0.000 0.871 0.129
I66.9 Occlusion and stenosis of unspecified cerebral artery
0.000 0.871 0.129
K43.7 Other and unspecified ventral hernia with gangrene
0.000 0.871 0.128
K43.6 Other and unspecified ventral hernia with obstruction, without gangrene
0.000 0.871 0.128
K43.5 Parastomal hernia without obstruction or gangrene
0.000 0.871 0.128
K43.4 Parastomal hernia with gangrene
0.000 0.871 0.128
K43.3 Parastomal hernia with obstruction, without gangrene
0.000 0.871 0.128
K43.2 Incisional hernia without obstruction or gangrene
0.000 0.871 0.128
K43.1 Ventral hernia with gangrene
0.000 0.871 0.128
I62.9 Intracranial haemorrhage (nontraumatic), unspecified
0.000 0.871 0.128
K46.9 Unspecified abdominal hernia without obstruction or gangrene
0.000 0.872 0.128
I95.0 Idiopathic hypotension
0.000 0.873 0.127
K90.8 Other intestinal malabsorption
0.000 0.875 0.125
I97.9 Postprocedural disorder of circulatory system, unspecified
0.000 0.877 0.123
I73.9 Peripheral vascular disease, unspecified
0.000 0.878 0.122
I70.20 Atherosclerosis of arteries of extremities (without gangrene)
0.000 0.879 0.121
K35.1 Acute appendicitis with peritoneal abscess
0.000 0.880 0.120
K81 Cholecystitis
0.000 0.881 0.119
K45 Other abdominal hernia
0.000 0.881 0.119
K46.1 Unspecified abdominal hernia with gangrene
0.000 0.882 0.118
K75.3 Granulomatous hepatitis, not elsewhere classified
0.000 0.883 0.117
I07 Rheumatic tricuspid valve diseases
0.000 0.884 0.116
K41.2 Bilateral femoral hernia, without obstruction or gangrene
0.000 0.885 0.115
K35.8 Acute appendicitis, other and unspecified
0.000 0.885 0.115
K44 Diaphragmatic hernia
0.000 0.886 0.114
I97.1 Other functional disturbances following cardiac surgery
0.000 0.887 0.112
I09 Other rheumatic heart diseases
0.000 0.887 0.112
K38 Other diseases of appendix
0.000 0.888 0.112
I69.8 Sequelae of other and unspecified cerebrovascular diseases
0.000 0.888 0.112
I06 Rheumatic aortic valve diseases
0.000 0.888 0.111
I97.8 Other postprocedural disorders of circulatory system, not elsewhere classified
0.000 0.890 0.110
I27.1 Kyphoscoliotic heart disease
0.000 0.891 0.108
I95.8 Other hypotension
0.000 0.895 0.105
K46.0 Unspecified abdominal hernia with obstruction, without gangrene
0.000 0.895 0.105
K35.0 Acute appendicitis with generalised peritonitis
0.000 0.897 0.103
K43.0 Ventral hernia with obstruction, without gangrene
0.000 0.902 0.098
K44.0 Diaphragmatic hernia with obstruction, without gangrene
0.000 0.904 0.096
I62.0 Subdural haemorrhage (acute) (nontraumatic)
0.000 0.906 0.094
K75.4 Autoimmune hepatitis
0.000 0.908 0.092
K35.3 Acute appendicitis with localized peritonitis
0.000 0.911 0.089
I05 Rheumatic mitral valve diseases
0.000 0.912 0.088
K37 Unspecified appendicitis
0.000 0.913 0.087
K45.1 Other specified abdominal hernia with gangrene
0.000 0.914 0.085
K90.9 Intestinal malabsorption, unspecified
0.000 0.916 0.084
K41.9 Unilateral or unspecified femoral hernia, without obstruction or gangrene
0.000 0.916 0.084
I07.9 Tricuspid valve disease, unspecified
0.000 0.916 0.083
I07.8 Other tricuspid valve diseases
0.000 0.916 0.083
I07.2 Tricuspid stenosis with insufficiency
0.000 0.916 0.083
I07.0 Tricuspid stenosis
0.000 0.916 0.083
K38.0 Hyperplasia of appendix
0.000 0.918 0.082
K92 Other diseases of digestive system
0.000 0.919 0.081
K45.8 Other specified abdominal hernia without obstruction or gangrene
0.000 0.919 0.081
I09.8 Other specified rheumatic heart diseases
0.000 0.919 0.081
I09.2 Chronic rheumatic pericarditis
0.000 0.919 0.081
I09.1 Rheumatic diseases of endocardium, valve unspecified
0.000 0.919 0.081
I09.0 Rheumatic myocarditis
0.000 0.919 0.081
K38.3 Fistula of appendix
0.000 0.919 0.081

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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