TreeWAS – Variant ID: rs4854307

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Click here to show this figure without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.992	0.008
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.991	0.009
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts	0.987	0.013
# Top node	0.984	0.016
Chapter X Diseases of the respiratory system	0.976	0.024
Chapter II Neoplasms	0.973	0.027
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.965	0.035
S20-S29 Injuries to the thorax	0.959	0.041
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.957	0.043
Chapter IV Endocrine, nutritional and metabolic diseases	0.955	0.045
T84.8 Other complications of internal orthopaedic prosthetic devices, implants and grafts	0.954	0.046
E10-E14 Diabetes mellitus	0.953	0.047
Chapter XX External causes of morbidity and mortality	0.950	0.050
E10 Insulin-dependent diabetes mellitus	0.948	0.052
C34 Malignant neoplasm of bronchus and lung	0.944	0.056
E10.9 Without complications	0.934	0.066
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.932	0.068
J09-J18 Influenza and pneumonia	0.928	0.072
D37-D48 Neoplasms of uncertain or unknown behaviour	0.926	0.074
C34.9 Bronchus or lung, unspecified	0.926	0.074
J95-J99 Other diseases of the respiratory system	0.926	0.074
Y95 Nosocomial condition	0.920	0.080
S22 Fracture of rib(s), sternum and thoracic spine	0.912	0.088
S00-S09 Injuries to the head	0.904	0.096
C85 Other and unspecified types of non-Hodgkin's lymphoma	0.903	0.097
J40-J47 Chronic lower respiratory diseases	0.899	0.101
J90-J94 Other diseases of pleura	0.894	0.106
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.885	0.115
C91 Lymphoid leukaemia	0.881	0.119
J98 Other respiratory disorders	0.880	0.120
C64-C68 Malignant neoplasms of urinary tract	0.874	0.126
T83 Complications of genito-urinary prosthetic devices, implants and grafts	0.865	0.135
J18 Pneumonia, organism unspecified	0.863	0.137
E11 Non-insulin-dependent diabetes mellitus	0.862	0.138
W00-W19 Falls	0.857	0.143
T84.0 Mechanical complication of internal joint prosthesis	0.849	0.151
T84.2 Mechanical complication of internal fixation device of other bones	0.849	0.151
C92 Myeloid leukaemia	0.841	0.159
E10.3 With ophthalmic complications	0.838	0.162
Chapter VI Diseases of the nervous system	0.837	0.163
C85.9 Non-Hodgkin's lymphoma, unspecified type	0.830	0.170
T20-T25 Burns and corrosions of external body surface, specified by site	0.824	0.176
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.823	0.177
C67 Malignant neoplasm of bladder	0.819	0.181
J98.1 Pulmonary collapse	0.816	0.184
C91.1 Chronic lymphocytic leukaemia	0.813	0.187
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.810	0.190
T84.5 Infection and inflammatory reaction due to internal joint prosthesis	0.810	0.190
S90-S99 Injuries to the ankle and foot	0.807	0.193
T84.3 Mechanical complication of other bone devices, implants and grafts	0.802	0.198
T84.9 Unspecified complication of internal orthopaedic prosthetic device, implant and graft	0.799	0.201
S22.4 Multiple fractures of ribs	0.799	0.201
C82 Follicular [nodular] non-Hodgkin's lymphoma	0.798	0.202
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.797	0.203
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.794	0.206
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.793	0.207
E10.4 With neurological complications	0.793	0.207
S80-S89 Injuries to the knee and lower leg	0.789	0.211
S70-S79 Injuries to the hip and thigh	0.787	0.213
E65-E68 Obesity and other hyperalimentation	0.786	0.214
S06 Intracranial injury	0.785	0.215
S22.3 Fracture of rib	0.784	0.216
J47 Bronchiectasis	0.783	0.217
J93 Pneumothorax	0.781	0.219
T81 Complications of procedures, not elsewhere classified	0.778	0.222
J85-J86 Suppurative and necrotic conditions of lower respiratory tract	0.777	0.223
Chapter VII Diseases of the eye and adnexa	0.776	0.224
S40-S49 Injuries to the shoulder and upper arm	0.776	0.224
Chapter XXII Codes for special purposes	0.776	0.224
J43 Emphysema	0.775	0.225
C34.0 Main bronchus	0.775	0.225
C34.1 Upper lobe, bronchus or lung	0.774	0.226
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.772	0.228
S27 Injury of other and unspecified intrathoracic organs	0.770	0.230
E50-E64 Other nutritional deficiencies	0.769	0.231
S22.0 Fracture of thoracic vertebra	0.768	0.231
T84.1 Mechanical complication of internal fixation device of bones of limb	0.767	0.233
V10-V19 Pedal cyclist injured in transport accident	0.767	0.233
E11.2 With renal complications	0.767	0.233
C92.0 Acute myeloid leukaemia	0.765	0.235
E10.6 With other specified complications	0.761	0.239
J18.9 Pneumonia, unspecified	0.761	0.239
D80-D89 Certain disorders involving the immune mechanism	0.759	0.241
S00 Superficial injury of head	0.757	0.243
W19 Unspecified fall	0.757	0.243
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs	0.756	0.244
J11 Influenza, virus not identified	0.756	0.244
J18.1 Lobar pneumonia, unspecified	0.755	0.245
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.755	0.245
T87 Complications peculiar to reattachment and amputation	0.752	0.248
S50-S59 Injuries to the elbow and forearm	0.751	0.249
M45-M49 Spondylopathies	0.750	0.250
D41 Neoplasm of uncertain or unknown behaviour of urinary organs	0.748	0.251
J95 Postprocedural respiratory disorders, not elsewhere classified	0.748	0.252
T15-T19 Effects of foreign body entering through natural orifice	0.747	0.253
C85.1 B-cell lymphoma, unspecified	0.746	0.254
D46 Myelodysplastic syndromes	0.743	0.257
J20-J22 Other acute lower respiratory infections	0.742	0.258
T88 Other complications of surgical and medical care, not elsewhere classified	0.740	0.260
J40 Bronchitis, not specified as acute or chronic	0.740	0.260
G62 Other polyneuropathies	0.740	0.260
S10-S19 Injuries to the neck	0.739	0.261
J15 Bacterial pneumonia, not elsewhere classified	0.739	0.261
T81.3 Disruption of operation wound, not elsewhere classified	0.738	0.262
C88 Malignant immunoproliferative diseases	0.737	0.263
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system	0.737	0.263
C83 Diffuse non-Hodgkin's lymphoma	0.736	0.264
T80 Complications following infusion, transfusion and therapeutic injection	0.733	0.267
S29 Other and unspecified injuries of thorax	0.731	0.268
T86 Failure and rejection of transplanted organs and tissues	0.731	0.269
G63 Polyneuropathy in diseases classified elsewhere	0.730	0.270
T79-T79 Certain early complications of trauma	0.729	0.271
S20 Superficial injury of thorax	0.727	0.273
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.727	0.273
W19.9 Unspecified place	0.726	0.274
C84 Peripheral and cutaneous T-cell lymphomas	0.724	0.276
D69 Purpura and other haemorrhagic conditions	0.723	0.277
T66-T78 Other and unspecified effects of external causes	0.723	0.277
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.722	0.278
M40-M43 Deforming dorsopathies	0.722	0.278
T83.1 Mechanical complication of other urinary devices and implants	0.719	0.281
S22.40 Multiple fractures of ribs (closed)	0.717	0.283
E11.8 With unspecified complications	0.716	0.284
S05 Injury of eye and orbit	0.715	0.285
W50-W64 Exposure to animate mechanical forces	0.714	0.285
T33-T35 Frostbite	0.711	0.289
T26-T28 Burns and corrosions confined to eye and internal organs	0.711	0.289
T00-T07 Injuries involving multiple body regions	0.711	0.289
T84.7 Infection and inflammatory reaction due to other internal orthopaedic prosthetic devices, implants and grafts	0.711	0.289
J91 Pleural effusion in conditions classified elsewhere	0.711	0.289
H53-H54 Visual disturbances and blindness	0.710	0.290
J98.9 Respiratory disorder, unspecified	0.706	0.294
S72 Fracture of femur	0.706	0.294
Chapter XVI Certain conditions originating in the perinatal period	0.706	0.294
J44 Other chronic obstructive pulmonary disease	0.704	0.296
J93.9 Pneumothorax, unspecified	0.704	0.296
V80-V89 Other land transport accidents	0.704	0.296
M05-M14 Inflammatory polyarthropathies	0.700	0.300
C32 Malignant neoplasm of larynx	0.700	0.300
S02 Fracture of skull and facial bones	0.700	0.300
E10.2 With renal complications	0.699	0.301
C67.9 Bladder, unspecified	0.699	0.301
T83.4 Mechanical complication of other prosthetic devices, implants and grafts in genital tract	0.699	0.301
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.698	0.302
C40-C41 Malignant neoplasms of bone and articular cartilage	0.698	0.302
W08 Fall involving other furniture	0.697	0.303
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle	0.697	0.303
D47.3 Essential (haemorrhagic) thrombocythaemia	0.695	0.305
D47.1 Chronic myeloproliferative disease	0.695	0.305
T83.5 Infection and inflammatory reaction due to prosthetic device, implant and graft in urinary system	0.694	0.306
D37.4 Colon	0.694	0.306
J94 Other pleural conditions	0.693	0.307
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue	0.692	0.308
C95 Leukaemia of unspecified cell type	0.692	0.308
C94 Other leukaemias of specified cell type	0.692	0.308
C93 Monocytic leukaemia	0.692	0.308
C86 Other specified types of T/NK-cell lymphoma	0.692	0.308
E13 Other specified diabetes mellitus	0.692	0.308
S22.30 Fracture of rib (closed)	0.692	0.308
J10 Influenza due to identified influenza virus	0.691	0.309
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.689	0.311
S28 Crushing injury of thorax and traumatic amputation of part of thorax	0.688	0.312
S26 Injury of heart	0.688	0.312
S25 Injury of blood vessels of thorax	0.688	0.312
S24 Injury of nerves and spinal cord at thorax level	0.688	0.312
S23 Dislocation, sprain and strain of joints and ligaments of thorax	0.688	0.312
S21 Open wound of thorax	0.688	0.312
J43.9 Emphysema, unspecified	0.687	0.313
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs	0.686	0.314
C38 Malignant neoplasm of heart, mediastinum and pleura	0.686	0.314
C31 Malignant neoplasm of accessory sinuses	0.686	0.314
C30 Malignant neoplasm of nasal cavity and middle ear	0.686	0.314
C37 Malignant neoplasm of thymus	0.686	0.314
C33 Malignant neoplasm of trachea	0.686	0.314
C67.6 Ureteric orifice	0.686	0.314
M48 Other spondylopathies	0.685	0.315
W14 Fall from tree	0.684	0.316
E12 Malnutrition-related diabetes mellitus	0.683	0.317
C34.2 Middle lobe, bronchus or lung	0.681	0.319
Y35-Y36 Legal intervention and operations of war	0.681	0.319
Y10-Y34 Event of undetermined intent	0.681	0.319
Y00-Y09 Assault	0.681	0.319
X85-X99 Assault	0.681	0.319
X58-X59 Accidental exposure to other and unspecified factors	0.681	0.319
X50-X57 Overexertion, travel and privation	0.681	0.319
X30-X39 Exposure to forces of nature	0.681	0.319
X20-X29 Contact with venomous animals and plants	0.681	0.319
X10-X19 Contact with heat and hot substances	0.681	0.319
X00-X09 Exposure to smoke, fire and flames	0.681	0.319
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.681	0.319
W75-W84 Other accidental threats to breathing	0.681	0.319
W65-W74 Accidental drowning and submersion	0.681	0.319
V98-V99 Other and unspecified transport accidents	0.681	0.319
V95-V97 Air and space transport accidents	0.681	0.319
V90-V94 Water transport accidents	0.681	0.319
V70-V79 Bus occupant injured in transport accident	0.681	0.319
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.681	0.319
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.681	0.319
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.681	0.319
V01-V09 Pedestrian injured in transport accident	0.681	0.319
E10.8 With unspecified complications	0.679	0.320
E10.7 With multiple complications	0.679	0.320
E10.0 With coma	0.679	0.320
C67.5 Bladder neck	0.678	0.322
V40-V49 Car occupant injured in transport accident	0.678	0.322
J98.5 Diseases of mediastinum, not elsewhere classified	0.678	0.322
C34.8 Overlapping lesion of bronchus and lung	0.677	0.323
W18 Other fall on same level	0.676	0.324
J98.0 Diseases of bronchus, not elsewhere classified	0.675	0.325
M06 Other rheumatoid arthritis	0.674	0.326
E10.5 With peripheral circulatory complications	0.673	0.327
G63.2 Diabetic polyneuropathy	0.672	0.328
Y91 Evidence of alcohol involvement determined by level of intoxication	0.672	0.328
W20-W49 Exposure to inanimate mechanical forces	0.672	0.328
J92 Pleural plaque	0.672	0.328
G60 Hereditary and idiopathic neuropathy	0.671	0.329
M43 Other deforming dorsopathies	0.671	0.329
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs	0.671	0.329
T21 Burn and corrosion of trunk	0.669	0.331
Y90 Evidence of alcohol involvement determined by blood alcohol level	0.668	0.331
Y98 Lifestyle-related condition	0.668	0.331
Y97 Environmental-pollution-related condition	0.668	0.331
Y96 Work-related condition	0.668	0.331
S01 Open wound of head	0.668	0.332
G90-G99 Other disorders of the nervous system	0.667	0.333
V20-V29 Motorcycle rider injured in transport accident	0.666	0.334
D39 Neoplasm of uncertain or unknown behaviour of female genital organs	0.666	0.334
E66 Obesity	0.666	0.334
S22.00 Fracture of thoracic vertebra (closed)	0.665	0.335
C65 Malignant neoplasm of renal pelvis	0.665	0.335
J17 Pneumonia in diseases classified elsewhere	0.665	0.335
J16 Pneumonia due to other infectious organisms, not elsewhere classified	0.665	0.335
J12 Viral pneumonia, not elsewhere classified	0.665	0.335
J09 Influenza due to certain identified influenza virus	0.665	0.335
T85 Complications of other internal prosthetic devices, implants and grafts	0.665	0.335
D60-D64 Aplastic and other anaemias	0.665	0.335
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands	0.664	0.336
D42 Neoplasm of uncertain or unknown behaviour of meninges	0.664	0.336
D40 Neoplasm of uncertain or unknown behaviour of male genital organs	0.664	0.336
J96 Respiratory failure, not elsewhere classified	0.664	0.336
T81.2 Accidental puncture and laceration during a procedure, not elsewhere classified	0.663	0.337
J98.8 Other specified respiratory disorders	0.661	0.339
E40-E46 Malnutrition	0.660	0.340
X40-X49 Accidental poisoning by and exposure to noxious substances	0.660	0.340
J14 Pneumonia due to Haemophilus influenzae	0.659	0.340
E11.4 With neurological complications	0.659	0.341
D45 Polycythaemia vera	0.658	0.342
C91.0 Acute lymphoblastic leukaemia	0.658	0.342
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection	0.657	0.343
T84.6 Infection and inflammatory reaction due to internal fixation device [any site]	0.657	0.343
E11.5 With peripheral circulatory complications	0.657	0.343
E55 Vitamin D deficiency	0.657	0.343
S91 Open wound of ankle and foot	0.657	0.343
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.655	0.345
S22.9 Fracture of bony thorax, part unspecified	0.654	0.346
S22.8 Fracture of other parts of bony thorax	0.654	0.346
S22.5 Flail chest	0.654	0.346
S22.1 Multiple fractures of thoracic spine	0.654	0.346
J42 Unspecified chronic bronchitis	0.653	0.347
M45 Ankylosing spondylitis	0.652	0.348
C66 Malignant neoplasm of ureter	0.651	0.349
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.650	0.350
C51-C58 Malignant neoplasms of female genital organs	0.650	0.350
M06.9 Rheumatoid arthritis, unspecified	0.649	0.351
S08 Traumatic amputation of part of head	0.648	0.352
S07 Crushing injury of head	0.648	0.352
S04 Injury of cranial nerves	0.648	0.352
S03 Dislocation, sprain and strain of joints and ligaments of head	0.648	0.352
T84.4 Mechanical complication of other internal orthopaedic devices, imnplants and grafts	0.648	0.352
C85.7 Other specified types of non-Hodgkin's lymphoma	0.647	0.353
C85.2 Mediastinal (thymic) large B-cell lymphoma	0.647	0.353
C85.0 Lymphosarcoma	0.647	0.353
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.645	0.354
T98 Sequelae of other and unspecified effects of external causes	0.645	0.355
J41 Simple and mucopurulent chronic bronchitis	0.644	0.356
T24 Burn and corrosion of hip and lower limb, except ankle and foot	0.643	0.356
D69.6 Thrombocytopenia, unspecified	0.643	0.357
D65 Disseminated intravascular coagulation [defibrination syndrome]	0.643	0.357
Y60-Y69 Misadventures to patients during surgical and medical care	0.642	0.358
H18 Other disorders of cornea	0.642	0.358
C43-C44 Melanoma and other malignant neoplasms of skin	0.642	0.358
E11.3 With ophthalmic complications	0.641	0.359
C82.9 Follicular non-Hodgkin's lymphoma, unspecified	0.640	0.360
D70-D77 Other diseases of blood and blood-forming organs	0.639	0.361
J90 Pleural effusion, not elsewhere classified	0.638	0.362
S82 Fracture of lower leg, including ankle	0.638	0.362
S22.2 Fracture of sternum	0.636	0.363
V18 Pedal cyclist injured in noncollision transport accident	0.636	0.364
S43.0 Dislocation of shoulder joint	0.636	0.364
H46-H48 Disorders of optic nerve and visual pathways	0.635	0.365
S01.8 Open wound of other parts of head	0.635	0.365
S06.6 Traumatic subarachnoid haemorrhage	0.635	0.365
X60-X84 Intentional self-harm	0.635	0.365
S27.0 Traumatic pneumothorax	0.634	0.366
J11.1 Influenza with other respiratory manifestations, virus not identified	0.633	0.367
G62.9 Polyneuropathy, unspecified	0.632	0.368
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.632	0.368
T92 Sequelae of injuries of upper limb	0.632	0.368
C91.9 Lymphoid leukaemia, unspecified	0.631	0.368
C91.8 Mature B-cell leukaemia Burkitt-type	0.631	0.368
C91.7 Other lymphoid leukaemia	0.631	0.368
C91.6 Prolymphocytic leukaemia of T-cell type	0.631	0.368
C91.5 Adult T-cell leukaemia	0.631	0.368
C91.4 Hairy-cell leukaemia	0.631	0.368
C91.3 Prolymphocytic leukaemia	0.631	0.368
C91.2 Subacute lymphocytic leukaemia	0.631	0.368
G00-G09 Inflammatory diseases of the central nervous system	0.631	0.369
J98.6 Disorders of diaphragm	0.631	0.369
J98.3 Compensatory emphysema	0.631	0.369
J98.2 Interstitial emphysema	0.631	0.369
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.630	0.370
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.630	0.370
T83.0 Mechanical complication of urinary (indwelling) catheter	0.628	0.372
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.628	0.372
C82.1 Mixed small cleaved and large cell, follicular	0.627	0.373
D47.4 Osteomyelofibrosis	0.627	0.373
C68 Malignant neoplasm of other and unspecified urinary organs	0.626	0.373
S00.0 Superficial injury of scalp	0.626	0.374
H53 Visual disturbances	0.626	0.374
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)	0.626	0.374
Y73 Gastro-enterology and urology devices associated with adverse incidents	0.625	0.375
C83.0 Small cell (diffuse)	0.624	0.375
J99 Respiratory disorders in diseases classified elsewhere	0.624	0.376
S90 Superficial injury of ankle and foot	0.623	0.376
D55-D59 Haemolytic anaemias	0.623	0.377
W10 Fall on and from stairs and steps	0.622	0.378
D00-D09 In situ neoplasms	0.621	0.379
D41.4 Bladder	0.621	0.379
E14 Unspecified diabetes mellitus	0.621	0.379
J95.8 Other postprocedural respiratory disorders	0.621	0.379
D86 Sarcoidosis	0.621	0.379
C81 Hodgkin's disease	0.620	0.379
T83.9 Unspecified complication of genito-urinary prosthetic device, implant and graft	0.620	0.379
T83.6 Infection and inflammatory reaction due to prosthetic device, implant and graft in genital tract	0.620	0.379
T83.2 Mechanical complication of graft of urinary organ	0.620	0.379
T81.7 Vascular complications following a procedure, not elsewhere classified	0.619	0.381
J18.8 Other pneumonia, organism unspecified	0.619	0.381
J18.2 Hypostatic pneumonia, unspecified	0.619	0.381
W02 Fall involving ice-skates, skis, roller-skates or skateboards	0.618	0.381
E11.7 With multiple complications	0.618	0.382
E11.6 With other specified complications	0.618	0.382
E11.0 With coma	0.618	0.382
S00.3 Superficial injury of nose	0.618	0.382
C34.3 Lower lobe, bronchus or lung	0.618	0.382
T14 Injury of unspecified body region	0.615	0.385
W17 Other fall from one level to another	0.614	0.385
W16 Diving or jumping into water causing injury other than drowning or submersion	0.614	0.385
W15 Fall from cliff	0.614	0.385
W12 Fall on and from scaffolding	0.614	0.385
W11 Fall on and from ladder	0.614	0.385
W09 Fall involving playground equipment	0.614	0.385
W05 Fall involving wheelchair	0.614	0.385
W04 Fall while being carried or supported by other persons	0.614	0.385
W03 Other fall on same level due to collision with, or pushing by, another person	0.614	0.385
W01 Fall on same level from slipping, tripping and stumbling	0.614	0.385
W00 Fall on same level involving ice and snow	0.614	0.385
C67.4 Posterior wall of bladder	0.614	0.386
J18.0 Bronchopneumonia, unspecified	0.613	0.387
S06.3 Focal brain injury	0.613	0.387
S06.4 Epidural haemorrhage	0.612	0.388
D46.9 Myelodysplastic syndrome, unspecified	0.611	0.389
S51 Open wound of forearm	0.610	0.390
S40 Superficial injury of shoulder and upper arm	0.609	0.391
H16 Keratitis	0.607	0.393
S06.2 Diffuse brain injury	0.607	0.393
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts	0.607	0.393
M43.1 Spondylolisthesis	0.607	0.393
Chapter I Certain infectious and parasitic diseases	0.607	0.393
T83.8 Other complications of genito-urinary prosthetic devices, implants and grafts	0.605	0.395
G70-G73 Diseases of myoneural junction and muscle	0.604	0.396
J13 Pneumonia due to Streptococcus pneumoniae	0.604	0.396
J85 Abscess of lung and mediastinum	0.604	0.396
G62.8 Other specified polyneuropathies	0.604	0.396
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use	0.603	0.397
C92.9 Myeloid leukaemia, unspecified	0.603	0.397
C92.8 Acute myeloid leukaemia with multilineage dysplasia	0.603	0.397
C92.7 Other myeloid leukaemia	0.603	0.397
C92.6 Acute myeloid leukaemia with 11q23-abnormality	0.603	0.397
C92.5 Acute myelomonocytic leukaemia	0.603	0.397
C92.4 Acute promyelocytic leukaemia	0.603	0.397
C92.3 Myeloid sarcoma	0.603	0.397
C92.2 Subacute myeloid leukaemia	0.603	0.397
S80 Superficial injury of lower leg	0.602	0.398
G20-G26 Extrapyramidal and movement disorders	0.602	0.398
D43.2 Brain, unspecified	0.601	0.399
M48.0 Spinal stenosis	0.601	0.399
S56 Injury of muscle and tendon at forearm level	0.601	0.399
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.600	0.400
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.600	0.400
T81.9 Unspecified complication of procedure	0.599	0.401
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level	0.599	0.401
S00.2 Other superficial injuries of eyelid and periocular area	0.597	0.403
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.596	0.404
J86 Pyothorax	0.595	0.405
S72.0 Fracture of neck of femur	0.595	0.405
H54 Blindness and low vision	0.594	0.406
T25 Burn and corrosion of ankle and foot	0.591	0.409
T23 Burn and corrosion of wrist and hand	0.591	0.409
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand	0.591	0.409
T20 Burn and corrosion of head and neck	0.591	0.409
D47.9 Neoplasm of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue, unspecified	0.590	0.410
D47.7 Other specified neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.590	0.410
D47.5 Chronic eosinophilic leukaemia [hypereosinophilic syndrome]	0.590	0.410
D47.0 Histiocytic and mast cell tumours of uncertain and unknown behaviour	0.590	0.410
G62.0 Drug-induced polyneuropathy	0.590	0.410
C90 Multiple myeloma and malignant plasma cell neoplasms	0.590	0.410
W21 Striking against or struck by sports equipment	0.589	0.410
C67.8 Overlapping lesion of bladder	0.587	0.412
C67.7 Urachus	0.587	0.412
C67.3 Anterior wall of bladder	0.587	0.412
C67.0 Trigone of bladder	0.587	0.412
U82-U85 Resistance to antimicrobial and antineoplastic drugs	0.586	0.414
S19 Other and unspecified injuries of neck	0.584	0.415
C67.1 Dome of bladder	0.584	0.415
S81 Open wound of lower leg	0.584	0.416
S00.1 Contusion of eyelid and periocular area	0.584	0.416
T17 Foreign body in respiratory tract	0.584	0.416
G90 Disorders of autonomic nervous system	0.583	0.417
W08.0 Home	0.583	0.417
G80-G83 Cerebral palsy and other paralytic syndromes	0.583	0.417
C67.2 Lateral wall of bladder	0.581	0.419
J22 Unspecified acute lower respiratory infection	0.581	0.419
M91-M94 Chondropathies	0.581	0.419
G64 Other disorders of peripheral nervous system	0.581	0.419
T88.7 Unspecified adverse effect of drug or medicament	0.581	0.419
T87.4 Infection of amputation stump	0.581	0.419
D69.3 Idiopathic thrombocytopenic purpura	0.580	0.420
S98 Traumatic amputation of ankle and foot	0.579	0.421
S97 Crushing injury of ankle and foot	0.579	0.421
S96 Injury of muscle and tendon at ankle and foot level	0.579	0.421
S95 Injury of blood vessels at ankle and foot level	0.579	0.421
S94 Injury of nerves at ankle and foot level	0.579	0.421
S00.7 Multiple superficial injuries of head	0.578	0.422
T90 Sequelae of injuries of head	0.578	0.422
M48.5 Collapsed vertebra, not elsewhere classified	0.577	0.423
E55.9 Vitamin D deficiency, unspecified	0.577	0.423
W06 Fall involving bed	0.576	0.424
J60-J70 Lung diseases due to external agents	0.576	0.424
S72.3 Fracture of shaft of femur	0.576	0.424
E53 Deficiency of other B group vitamins	0.575	0.424
W07 Fall involving chair	0.574	0.426
C88.0 Waldenstrom's macroglobulinaemia	0.573	0.427
S22.41 Multiple fractures of ribs (open)	0.573	0.427
C82.7 Other types of follicular non-Hodgkin's lymphoma	0.572	0.428
C82.6 Cutaneous follicle centre lymphoma	0.572	0.428
C82.5 Diffuse follicle centre lymphoma	0.572	0.428
C82.4 Follicular lymphoma grade IIIb	0.572	0.428
C82.3 Follicular lymphoma grade IIIa	0.572	0.428
C82.2 Large cell, follicular	0.572	0.428
C82.0 Small cleaved cell, follicular	0.572	0.428
G60.0 Hereditary motor and sensory neuropathy	0.572	0.428
J15.7 Pneumonia due to Mycoplasma pneumoniae	0.572	0.428
T95 Sequelae of burns, corrosions and frostbite	0.571	0.428
T94 Sequelae of injuries involving multiple and unspecified body regions	0.571	0.428
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source	0.571	0.428
T96 Sequelae of poisoning by drugs, medicaments and biological substances	0.571	0.428
S82.6 Fracture of lateral malleolus	0.571	0.429
C54 Malignant neoplasm of corpus uteri	0.571	0.429
T91 Sequelae of injuries of neck and trunk	0.571	0.429
S06.8 Other intracranial injuries	0.571	0.429
G30-G32 Other degenerative diseases of the nervous system	0.571	0.429
J15.2 Pneumonia due to staphylococcus	0.570	0.429
M60-M63 Disorders of muscles	0.569	0.431
D67 Hereditary factor IX deficiency	0.569	0.431
D66 Hereditary factor VIII deficiency	0.569	0.431
D80 Immunodeficiency with predominantly antibody defects	0.568	0.432
S29.9 Unspecified injury of thorax	0.568	0.432
J46 Status asthmaticus	0.568	0.432
H19 Disorders of sclera and cornea in diseases classified elsewhere	0.567	0.433
S05.0 Injury of conjunctiva and corneal abrasion without mention of foreign body	0.567	0.433
J98.4 Other disorders of lung	0.566	0.434
S88 Traumatic amputation of lower leg	0.566	0.434
S87 Crushing injury of lower leg	0.566	0.434
S86 Injury of muscle and tendon at lower leg level	0.566	0.434
S85 Injury of blood vessels at lower leg level	0.566	0.434
S84 Injury of nerves at lower leg level	0.566	0.434
C43 Malignant melanoma of skin	0.565	0.434
E20-E35 Disorders of other endocrine glands	0.565	0.435
E66.8 Other obesity	0.565	0.435
M00-M03 Infectious arthropathies	0.565	0.435
M86-M90 Other osteopathies	0.564	0.436
S78 Traumatic amputation of hip and thigh	0.564	0.436
S77 Crushing injury of hip and thigh	0.564	0.436
S76 Injury of muscle and tendon at hip and thigh level	0.564	0.436
S75 Injury of blood vessels at hip and thigh level	0.564	0.436
S74 Injury of nerves at hip and thigh level	0.564	0.436
S73 Dislocation, sprain and strain of joint and ligaments of hip	0.564	0.436
S71 Open wound of hip and thigh	0.564	0.436
E67 Other hyperalimentation	0.564	0.436
E68 Sequelae of hyperalimentation	0.564	0.436
E65 Localised adiposity	0.564	0.436
H55-H59 Other disorders of eye and adnexa	0.564	0.436
T75 Effects of other external causes	0.564	0.436
C92.1 Chronic myeloid leukaemia	0.563	0.436
T68 Hypothermia	0.563	0.437
A30-A49 Other bacterial diseases	0.563	0.437
S06.9 Intracranial injury, unspecified	0.563	0.437
S06.7 Intracranial injury with prolonged coma	0.563	0.437
S06.1 Traumatic cerebral oedema	0.563	0.437
M45.X9 Ankylosing spondylitis (Site unspecified)	0.563	0.437

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations