TreeWAS – Variant ID: rs4868006

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Click here to show this figure without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability
# Top node	1.000	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	1.000	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	1.000	0.000
E70-E90 Metabolic disorders	1.000	0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.999	0.001
Chapter V Mental and behavioural disorders	0.997	0.003
Chapter IX Diseases of the circulatory system	0.997	0.003
E87 Other disorders of fluid, electrolyte and acid-base balance	0.997	0.003
S00-S09 Injuries to the head	0.993	0.007
E87.1 Hypo-osmolality and hyponatraemia	0.992	0.008
Chapter XX External causes of morbidity and mortality	0.992	0.008
F30-F39 Mood [affective] disorders	0.991	0.009
I60-I69 Cerebrovascular diseases	0.988	0.012
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.984	0.016
I20-I25 Ischaemic heart diseases	0.974	0.026
I20 Angina pectoris	0.969	0.031
S02 Fracture of skull and facial bones	0.969	0.031
M80-M85 Disorders of bone density and structure	0.967	0.033
E89.0 Postprocedural hypothyroidism	0.964	0.036
F31 Bipolar affective disorder	0.961	0.039
I20.0 Unstable angina	0.961	0.039
Chapter VI Diseases of the nervous system	0.959	0.041
I63 Cerebral infarction	0.958	0.042
E20-E35 Disorders of other endocrine glands	0.954	0.046
E83 Disorders of mineral metabolism	0.954	0.046
E50-E64 Other nutritional deficiencies	0.953	0.047
M45-M49 Spondylopathies	0.948	0.052
I30-I52 Other forms of heart disease	0.947	0.053
E87.2 Acidosis	0.942	0.058
I20.8 Other forms of angina pectoris	0.941	0.059
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.933	0.067
S80-S89 Injuries to the knee and lower leg	0.930	0.070
M40-M43 Deforming dorsopathies	0.929	0.071
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.929	0.071
I64 Stroke, not specified as haemorrhage or infarction	0.918	0.082
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.914	0.086
I34 Nonrheumatic mitral valve disorders	0.911	0.089
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.909	0.091
E27 Other disorders of adrenal gland	0.903	0.097
S06 Intracranial injury	0.903	0.097
E53 Deficiency of other B group vitamins	0.897	0.103
I42 Cardiomyopathy	0.896	0.104
Chapter I Certain infectious and parasitic diseases	0.895	0.105
F33 Recurrent depressive disorder	0.893	0.107
S02.2 Fracture of nasal bones	0.889	0.111
I67 Other cerebrovascular diseases	0.889	0.111
I69 Sequelae of cerebrovascular disease	0.888	0.112
M47 Spondylosis	0.886	0.114
F32 Depressive episode	0.885	0.115
S60-S69 Injuries to the wrist and hand	0.883	0.117
E83.5 Disorders of calcium metabolism	0.882	0.118
T66-T78 Other and unspecified effects of external causes	0.882	0.118
I63.4 Cerebral infarction due to embolism of cerebral arteries	0.881	0.119
F31.9 Bipolar affective disorder, unspecified	0.875	0.125
M43 Other deforming dorsopathies	0.872	0.128
S90-S99 Injuries to the ankle and foot	0.870	0.130
S66 Injury of muscle and tendon at wrist and hand level	0.870	0.130
M47.9 Spondylosis, unspecified	0.866	0.134
S02.4 Fracture of malar and maxillary bones	0.863	0.136
S00 Superficial injury of head	0.863	0.137
I27 Other pulmonary heart diseases	0.862	0.138
M50-M54 Other dorsopathies	0.859	0.141
E53.8 Deficiency of other specified B group vitamins	0.858	0.142
X60-X84 Intentional self-harm	0.855	0.145
Y40 Systemic antibiotics	0.855	0.145
I34.0 Mitral (valve) insufficiency	0.852	0.148
M05-M14 Inflammatory polyarthropathies	0.852	0.148
G80-G83 Cerebral palsy and other paralytic syndromes	0.849	0.150
E23 Hypofunction and other disorders of pituitary gland	0.848	0.152
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.844	0.156
E27.1 Primary adrenocortical insufficiency	0.842	0.158
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts	0.842	0.158
Chapter XII Diseases of the skin and subcutaneous tissue	0.841	0.159
E85 Amyloidosis	0.841	0.159
M70-M79 Other soft tissue disorders	0.838	0.162
Chapter VIII Diseases of the ear and mastoid process	0.838	0.162
F60-F69 Disorders of adult personality and behaviour	0.836	0.164
Y45 Analgesics, antipyretics and anti-inflammatory drugs	0.836	0.164
M43.1 Spondylolisthesis	0.835	0.165
S82 Fracture of lower leg, including ankle	0.833	0.167
S02.20 Fracture of nasal bones (closed)	0.832	0.168
T84.8 Other complications of internal orthopaedic prosthetic devices, implants and grafts	0.823	0.177
M81 Osteoporosis without pathological fracture	0.821	0.179
I44 Atrioventricular and left bundle-branch block	0.820	0.180
M06 Other rheumatoid arthritis	0.819	0.181
I63.9 Cerebral infarction, unspecified	0.819	0.181
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms	0.818	0.182
E86 Volume depletion	0.816	0.184
S32 Fracture of lumbar spine and pelvis	0.816	0.184
F99-F99 Unspecified mental disorder	0.815	0.185
X20-X29 Contact with venomous animals and plants	0.815	0.185
L80-L99 Other disorders of the skin and subcutaneous tissue	0.815	0.185
I63.8 Other cerebral infarction	0.814	0.186
E83.1 Disorders of iron metabolism	0.814	0.186
E89.2 Postprocedural hypoparathyroidism	0.812	0.188
I22 Subsequent myocardial infarction	0.811	0.189
M60-M63 Disorders of muscles	0.811	0.189
M80 Osteoporosis with pathological fracture	0.810	0.190
F80-F89 Disorders of psychological development	0.808	0.192
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.808	0.192
S10-S19 Injuries to the neck	0.807	0.193
I51 Complications and ill-defined descriptions of heart disease	0.806	0.194
M84 Disorders of continuity of bone	0.805	0.195
Y85-Y89 Sequelae of external causes of morbidity and mortality	0.805	0.195
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.803	0.197
I27.0 Primary pulmonary hypertension	0.801	0.199
M79 Other soft tissue disorders, not elsewhere classified	0.800	0.200
G70-G73 Diseases of myoneural junction and muscle	0.799	0.201
S02.1 Fracture of base of skull	0.798	0.202
G90-G99 Other disorders of the nervous system	0.797	0.203
I67.8 Other specified cerebrovascular diseases	0.797	0.203
S66.1 Injury of flexor muscle and tendon of other finger at wrist and hand level	0.796	0.204
T20-T25 Burns and corrosions of external body surface, specified by site	0.796	0.204
M82 Osteoporosis in diseases classified elsewhere	0.796	0.204
M43.16 Spondylolisthesis (Lumbar region)	0.794	0.206
M46 Other inflammatory spondylopathies	0.793	0.207
Y00-Y09 Assault	0.792	0.208
S02.40 Fracture of malar and maxillary bones (closed)	0.788	0.212
I42.1 Obstructive hypertrophic cardiomyopathy	0.787	0.213
S20-S29 Injuries to the thorax	0.787	0.213
I34.1 Mitral (valve) prolapse	0.786	0.214
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.786	0.214
S40-S49 Injuries to the shoulder and upper arm	0.786	0.214
T00-T07 Injuries involving multiple body regions	0.785	0.215
S06.3 Focal brain injury	0.785	0.215
I33 Acute and subacute endocarditis	0.784	0.216
X50-X57 Overexertion, travel and privation	0.783	0.217
F33.1 Recurrent depressive disorder, current episode moderate	0.782	0.217
S02.8 Fractures of other skull and facial bones	0.782	0.218
G82 Paraplegia and tetraplegia	0.781	0.219
S66.2 Injury of extensor muscle and tendon of thumb at wrist and hand level	0.781	0.219
W20-W49 Exposure to inanimate mechanical forces	0.781	0.219
M65-M68 Disorders of synovium and tendon	0.780	0.220
G61 Inflammatory polyneuropathy	0.780	0.220
B15-B19 Viral hepatitis	0.779	0.221
F32.3 Severe depressive episode with psychotic symptoms	0.777	0.223
Y51 Drugs primarily affecting the autonomic nervous system	0.776	0.224
S06.6 Traumatic subarachnoid haemorrhage	0.776	0.224
M47.99 Spondylosis, unspecified (Site unspecified)	0.776	0.224
M48 Other spondylopathies	0.776	0.224
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction	0.773	0.226
S00.9 Superficial injury of head, part unspecified	0.773	0.227
L91 Hypertrophic disorders of skin	0.771	0.229
M06.9 Rheumatoid arthritis, unspecified	0.769	0.231
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.769	0.231
I67.9 Cerebrovascular disease, unspecified	0.769	0.231
G40-G47 Episodic and paroxysmal disorders	0.769	0.231
S83 Dislocation, sprain and strain of joints and ligaments of knee	0.768	0.232
X40-X49 Accidental poisoning by and exposure to noxious substances	0.768	0.232
M47.96 Spondylosis, unspecified (Lumbar region)	0.767	0.233
M85 Other disorders of bone density and structure	0.766	0.234
E55 Vitamin D deficiency	0.766	0.234
S02.0 Fracture of vault of skull	0.765	0.235
M53 Other dorsopathies, not elsewhere classified	0.765	0.235
H90-H95 Other disorders of ear	0.764	0.236
Y40.9 Systemic antibiotic, unspecified	0.761	0.239
G62 Other polyneuropathies	0.760	0.240
F00-F09 Organic, including symptomatic, mental disorders	0.759	0.241
I23 Certain current complications following acute myocardial infarction	0.758	0.242
Y40.0 Penicillins	0.757	0.243
M47.92 Spondylosis, unspecified (Cervical region)	0.757	0.243
S81 Open wound of lower leg	0.756	0.244
I44.2 Atrioventricular block, complete	0.755	0.245
M50 Cervical disk disorders	0.755	0.245
F23 Acute and transient psychotic disorders	0.754	0.246
T78 Adverse effects, not elsewhere classified	0.754	0.246
T15-T19 Effects of foreign body entering through natural orifice	0.751	0.249
T84.5 Infection and inflammatory reaction due to internal joint prosthesis	0.751	0.249
S30 Superficial injury of abdomen, lower back and pelvis	0.750	0.250
I51.8 Other ill-defined heart diseases	0.750	0.250
I38 Endocarditis, valve unspecified	0.749	0.251
S66.7 Injury of multiple extensor muscles and tendons at wrist and hand level	0.749	0.251
L20-L30 Dermatitis and eczema	0.749	0.251
I22.9 Subsequent myocardial infarction of unspecified site	0.749	0.251
E80 Disorders of porphyrin and bilirubin metabolism	0.748	0.252
F33.3 Recurrent depressive disorder, current episode severe with psychotic symptoms	0.748	0.252
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms	0.747	0.253
L91.8 Other hypertrophic disorders of skin	0.745	0.255
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.743	0.257
S70-S79 Injuries to the hip and thigh	0.742	0.258
X10-X19 Contact with heat and hot substances	0.740	0.260
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified	0.737	0.263
I26 Pulmonary embolism	0.736	0.264
G63 Polyneuropathy in diseases classified elsewhere	0.735	0.265
Y41 Other systemic anti-infectives and antiparasitics	0.735	0.265
I44.7 Left bundle-branch block, unspecified	0.735	0.265
I42.8 Other cardiomyopathies	0.734	0.266
M00-M03 Infectious arthropathies	0.733	0.267
E83.4 Disorders of magnesium metabolism	0.733	0.267
E89.3 Postprocedural hypopituitarism	0.733	0.267
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms	0.732	0.268
Y85 Sequelae of transport accidents	0.730	0.270
G60 Hereditary and idiopathic neuropathy	0.729	0.271
L92 Granulomatous disorders of skin and subcutaneous tissue	0.729	0.271
E27.4 Other and unspecified adrenocortical insufficiency	0.727	0.273
E00-E07 Disorders of thyroid gland	0.726	0.274
X58-X59 Accidental exposure to other and unspecified factors	0.726	0.274
V40-V49 Car occupant injured in transport accident	0.725	0.275
S05 Injury of eye and orbit	0.724	0.275
S06.2 Diffuse brain injury	0.724	0.276
S66.3 Injury of extensor muscle and tendon of other finger at wrist and hand level	0.724	0.276
W50-W64 Exposure to animate mechanical forces	0.724	0.276
F31.0 Bipolar affective disorder, current episode hypomanic	0.724	0.276
S92 Fracture of foot, except ankle	0.722	0.278
A30-A49 Other bacterial diseases	0.722	0.278
M50.3 Other cervical disk degeneration	0.722	0.278
E26 Hyperaldosteronism	0.722	0.278
I42.2 Other hypertrophic cardiomyopathy	0.722	0.278
S82.4 Fracture of fibula alone	0.721	0.279
L89 Decubitus ulcer	0.721	0.279
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level	0.720	0.279
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms	0.719	0.281
E73 Lactose intolerance	0.719	0.281
V20-V29 Motorcycle rider injured in transport accident	0.718	0.282
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries	0.718	0.282
T68 Hypothermia	0.718	0.282
E61 Deficiency of other nutrient elements	0.717	0.283
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283
T33-T35 Frostbite	0.717	0.283
T26-T28 Burns and corrosions confined to eye and internal organs	0.717	0.283
E84 Cystic fibrosis	0.717	0.283
E79 Disorders of purine and pyrimidine metabolism	0.717	0.283
E77 Disorders of glycoprotein metabolism	0.717	0.283
E76 Disorders of glycosaminoglycan metabolism	0.717	0.283
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.717	0.283
E74 Other disorders of carbohydrate metabolism	0.717	0.283
E72 Other disorders of amino-acid metabolism	0.717	0.283
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.717	0.283
E70 Disorders of aromatic amino-acid metabolism	0.717	0.283
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.717	0.283
F31.3 Bipolar affective disorder, current episode mild or moderate depression	0.715	0.285
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.715	0.285
F70-F79 Mental retardation	0.715	0.285
I00-I02 Acute rheumatic fever	0.715	0.285
E87.4 Mixed disorder of acid-base balance	0.714	0.285
I30 Acute pericarditis	0.714	0.286
V80-V89 Other land transport accidents	0.713	0.286
M86-M90 Other osteopathies	0.713	0.287
E20 Hypoparathyroidism	0.712	0.288
S08 Traumatic amputation of part of head	0.712	0.288
S07 Crushing injury of head	0.712	0.288
S04 Injury of cranial nerves	0.712	0.288
S03 Dislocation, sprain and strain of joints and ligaments of head	0.712	0.288
M79.5 Residual foreign body in soft tissue	0.711	0.289
Y35-Y36 Legal intervention and operations of war	0.711	0.289
Y10-Y34 Event of undetermined intent	0.711	0.289
X85-X99 Assault	0.711	0.289
X30-X39 Exposure to forces of nature	0.711	0.289
X00-X09 Exposure to smoke, fire and flames	0.711	0.289
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.711	0.289
W75-W84 Other accidental threats to breathing	0.711	0.289
W65-W74 Accidental drowning and submersion	0.711	0.289
V98-V99 Other and unspecified transport accidents	0.711	0.289
V95-V97 Air and space transport accidents	0.711	0.289
V90-V94 Water transport accidents	0.711	0.289
V70-V79 Bus occupant injured in transport accident	0.711	0.289
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.711	0.289
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.711	0.289
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.711	0.289
V01-V09 Pedestrian injured in transport accident	0.711	0.289
F38 Other mood [affective] disorders	0.711	0.289
F34 Persistent mood [affective] disorders	0.711	0.289
F39 Unspecified mood [affective] disorder	0.711	0.289
B25-B34 Other viral diseases	0.710	0.290
A15-A19 Tuberculosis	0.710	0.290
M81.9 Osteoporosis, unspecified	0.710	0.290
E85.9 Amyloidosis, unspecified	0.709	0.291
H80-H83 Diseases of inner ear	0.709	0.291
I68 Cerebrovascular disorders in diseases classified elsewhere	0.708	0.292
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction	0.708	0.292
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries	0.708	0.292
S31 Open wound of abdomen, lower back and pelvis	0.706	0.294
E89.9 Postprocedural endocrine and metabolic disorder, unspecified	0.706	0.294
E89.8 Other postprocedural endocrine and metabolic disorders	0.706	0.294
E89.6 Postprocedural adrenocortical(-medullary) hypofunction	0.706	0.294
E89.5 Postprocedural testicular hypofunction	0.706	0.294
E89.4 Postprocedural ovarian failure	0.706	0.294
E89.1 Postprocedural hypoinsulinaemia	0.706	0.294
M49 Spondylopathies in diseases classified elsewhere	0.705	0.295
E34 Other endocrine disorders	0.705	0.295
T79-T79 Certain early complications of trauma	0.704	0.296
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.704	0.296
M79.1 Myalgia	0.704	0.296
E29 Testicular dysfunction	0.702	0.298
B90-B94 Sequelae of infectious and parasitic diseases	0.701	0.299
S86 Injury of muscle and tendon at lower leg level	0.700	0.300
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.700	0.300
Y84.2 Radiological procedure and radiotherapy	0.700	0.300
S06.30 Focal brain injury (without open intracranial wound)	0.700	0.300
M41 Scoliosis	0.700	0.300
Y45.0 Opioids and related analgesics	0.699	0.301
Y53 Agents primarily affecting the gastro-intestinal system	0.698	0.302
M06.94 Rheumatoid arthritis, unspecified (Hand)	0.698	0.302
F23.9 Acute and transient psychotic disorder, unspecified	0.698	0.302
M53.3 Sacrococcygeal disorders, not elsewhere classified	0.698	0.302
S64 Injury of nerves at wrist and hand level	0.696	0.304
E27.2 Addisonian crisis	0.696	0.304
S82.1 Fracture of upper end of tibia	0.695	0.304
S02.9 Fracture of skull and facial bones, part unspecified	0.694	0.305
S02.7 Multiple fractures involving skull and facial bones	0.694	0.305
X68 Intentional self-poisoning by and exposure to pesticides	0.694	0.306
M83 Adult osteomalacia	0.693	0.307
S32.0 Fracture of lumbar vertebra	0.693	0.307
I31 Other diseases of pericardium	0.692	0.308
E23.0 Hypopituitarism	0.690	0.310
Y84.6 Urinary catheterisation	0.690	0.310
T84.2 Mechanical complication of internal fixation device of other bones	0.690	0.310
Y49 Psychotropic drugs, not elsewhere classified	0.689	0.310
F31.8 Other bipolar affective disorders	0.689	0.311
F31.7 Bipolar affective disorder, currently in remission	0.689	0.311
F31.6 Bipolar affective disorder, current episode mixed	0.689	0.311
G30-G32 Other degenerative diseases of the nervous system	0.689	0.311
X23 Contact with hornets, wasps and bees	0.689	0.311
S83.2 Tear of meniscus, current	0.689	0.311
S00.7 Multiple superficial injuries of head	0.689	0.311
E23.6 Other disorders of pituitary gland	0.688	0.312
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	0.688	0.312
F32.2 Severe depressive episode without psychotic symptoms	0.688	0.312
I42.9 Cardiomyopathy, unspecified	0.687	0.313
E40-E46 Malnutrition	0.687	0.313
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic	0.687	0.313
I63.1 Cerebral infarction due to embolism of precerebral arteries	0.687	0.313
I63.0 Cerebral infarction due to thrombosis of precerebral arteries	0.687	0.313
M47.2 Other spondylosis with radiculopathy	0.687	0.313
M47.90 Spondylosis, unspecified (Multiple sites in spine)	0.686	0.314
S20 Superficial injury of thorax	0.685	0.315
M84.1 Nonunion of fracture [pseudarthrosis]	0.685	0.315
S06.60 Traumatic subarachnoid haemorrhage (without open intracranial wound)	0.685	0.315
F99 Mental disorder, not otherwise specified	0.685	0.315
E35 Disorders of endocrine glands in diseases classified elsewhere	0.684	0.316
E32 Diseases of thymus	0.684	0.316
E31 Polyglandular dysfunction	0.684	0.316
E30 Disorders of puberty, not elsewhere classified	0.684	0.316
E25 Adrenogenital disorders	0.684	0.316
E24 Cushing's syndrome	0.684	0.316
E83.9 Disorder of mineral metabolism, unspecified	0.684	0.316
E83.8 Other disorders of mineral metabolism	0.684	0.316
E83.2 Disorders of zinc metabolism	0.684	0.316
E83.0 Disorders of copper metabolism	0.684	0.316
G82.1 Spastic paraplegia	0.683	0.317
E64 Sequelae of malnutrition and other nutritional deficiencies	0.683	0.317
E63 Other nutritional deficiencies	0.683	0.317
E56 Other vitamin deficiencies	0.683	0.317
E51 Thiamine deficiency	0.683	0.317
E50 Vitamin A deficiency	0.683	0.317
E60 Dietary zinc deficiency	0.683	0.317
E59 Dietary selenium deficiency	0.683	0.317
E58 Dietary calcium deficiency	0.683	0.317
E54 Ascorbic acid deficiency	0.683	0.317
E52 Niacin deficiency [pellagra]	0.683	0.317
S00.1 Contusion of eyelid and periocular area	0.682	0.318
B20-B24 Human immunodeficiency virus [HIV] disease	0.682	0.318
T84.1 Mechanical complication of internal fixation device of bones of limb	0.682	0.318
X62 Intentional self-poisoning by and exposure to narcotics and psychodysleptics [hallucinogens], not elsewhere classified	0.682	0.318
G71 Primary disorders of muscles	0.682	0.318
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.681	0.319
F30 Manic episode	0.681	0.319
T84.6 Infection and inflammatory reaction due to internal fixation device [any site]	0.681	0.319
M43.17 Spondylolisthesis (Lumbosacral region)	0.681	0.319
I69.3 Sequelae of cerebral infarction	0.680	0.320
I52 Other heart disorders in diseases classified elsewhere	0.679	0.321
I48 Atrial fibrillation and flutter	0.679	0.321
I43 Cardiomyopathy in diseases classified elsewhere	0.679	0.321
I41 Myocarditis in diseases classified elsewhere	0.679	0.321
I40 Acute myocarditis	0.679	0.321
I39 Endocarditis and heart valve disorders in diseases classified elsewhere	0.679	0.321
I32 Pericarditis in diseases classified elsewhere	0.679	0.321
Y60-Y69 Misadventures to patients during surgical and medical care	0.678	0.322
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.677	0.323
I36 Nonrheumatic tricuspid valve disorders	0.677	0.323
M48.0 Spinal stenosis	0.677	0.323
E87.3 Alkalosis	0.676	0.324
I69.0 Sequelae of subarachnoid haemorrhage	0.676	0.324
S02.3 Fracture of orbital floor	0.675	0.325
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.675	0.325
F10-F19 Mental and behavioural disorders due to psychoactive substance use	0.675	0.325
S02.10 Fracture of base of skull (closed)	0.675	0.325
S91 Open wound of ankle and foot	0.675	0.325
S81.8 Open wound of other parts of lower leg	0.674	0.325
F60 Specific personality disorders	0.674	0.326
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.674	0.326
L84 Corns and callosities	0.674	0.326
F32.1 Moderate depressive episode	0.673	0.327
E23.7 Disorder of pituitary gland, unspecified	0.673	0.327
M82.1 Osteoporosis in endocrine disorders	0.673	0.327
G00-G09 Inflammatory diseases of the central nervous system	0.672	0.328
Y44 Agents primarily affecting blood constituents	0.671	0.329
M46.9 Inflammatory spondylopathy, unspecified	0.671	0.329
S01 Open wound of head	0.670	0.330
S82.0 Fracture of patella	0.670	0.330
I34.9 Nonrheumatic mitral valve disorder, unspecified	0.670	0.330
T78.4 Allergy, unspecified	0.670	0.330
S06.9 Intracranial injury, unspecified	0.669	0.331
Y59 Other and unspecified vaccines and biological substances	0.669	0.331
Y58 Bacterial vaccines	0.669	0.331
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs	0.669	0.331
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system	0.669	0.331
Y50 Central nervous system stimulants, not elsewhere classified	0.669	0.331
Y48 Anaesthetics and therapeutic gases	0.669	0.331
Y47 Sedatives, hypnotics and antianxiety drugs	0.669	0.331
Y46 Antiepileptics and anti-Parkinsonism drugs	0.669	0.331
F69 Unspecified disorder of adult personality and behaviour	0.668	0.332
T84.7 Infection and inflammatory reaction due to other internal orthopaedic prosthetic devices, implants and grafts	0.668	0.332
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.668	0.332
B50-B64 Protozoal diseases	0.667	0.332
F32.0 Mild depressive episode	0.667	0.333
B00-B09 Viral infections characterized by skin and mucous membrane lesions	0.667	0.333
S88 Traumatic amputation of lower leg	0.667	0.333
S87 Crushing injury of lower leg	0.667	0.333
S85 Injury of blood vessels at lower leg level	0.667	0.333
S84 Injury of nerves at lower leg level	0.667	0.333
I33.0 Acute and subacute infective endocarditis	0.666	0.334
M42 Spinal osteochondrosis	0.666	0.334
M40 Kyphosis and lordosis	0.666	0.334
I28 Other diseases of pulmonary vessels	0.666	0.334
S32.1 Fracture of sacrum	0.666	0.334
M06.0 Seronegative rheumatoid arthritis	0.666	0.334
S06.5 Traumatic subdural haemorrhage	0.666	0.334
S82.2 Fracture of shaft of tibia	0.665	0.335
H92 Otalgia and effusion of ear	0.665	0.335
G81 Hemiplegia	0.665	0.335
Y51.7 Beta-Adrenoreceptor antagonists, not elsewhere classified	0.664	0.336
G61.9 Inflammatory polyneuropathy, unspecified	0.663	0.337
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.663	0.337
I69.1 Sequelae of intracerebral haemorrhage	0.662	0.337
I37 Pulmonary valve disorders	0.662	0.338
G40 Epilepsy	0.662	0.338
M80.9 Unspecified osteoporosis with pathological fracture	0.662	0.338
E87.6 Hypokalaemia	0.662	0.338
F81 Specific developmental disorders of scholastic skills	0.661	0.339
E87.5 Hyperkalaemia	0.661	0.339
G44 Other headache syndromes	0.660	0.340
E83.3 Disorders of phosphorus metabolism	0.660	0.340
S89 Other and unspecified injuries of lower leg	0.658	0.342
S00.0 Superficial injury of scalp	0.657	0.343
M06.4 Inflammatory polyarthropathy	0.655	0.345
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis	0.655	0.345
S37 Injury of urinary and pelvic organs	0.655	0.345
S36 Injury of intra-abdominal organs	0.655	0.345
S35 Injury of blood vessels at abdomen, lower back and pelvis level	0.655	0.345
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level	0.655	0.345
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis	0.655	0.345
V10-V19 Pedal cyclist injured in transport accident	0.654	0.346
I42.0 Dilated cardiomyopathy	0.654	0.346
M65 Synovitis and tenosynovitis	0.654	0.346
I34.8 Other nonrheumatic mitral valve disorders	0.653	0.347
I34.2 Nonrheumatic mitral (valve) stenosis	0.653	0.347
H93 Other disorders of ear, not elsewhere classified	0.653	0.347
G82.2 Paraplegia, unspecified	0.652	0.347
Y57 Other and unspecified drugs and medicaments	0.652	0.348
G64 Other disorders of peripheral nervous system	0.652	0.348
Y85.0 Sequelae of motor-vehicle accident	0.652	0.348
S46 Injury of muscle and tendon at shoulder and upper arm level	0.652	0.348
S49 Other and unspecified injuries of shoulder and upper arm	0.651	0.349
X63 Intentional self-poisoning by and exposure to other drugs acting on the autonomic nervous system	0.651	0.349
M71 Other bursopathies	0.650	0.350
M53.38 Sacrococcygeal disorders, not elsewhere classified-Sacral/s	0.649	0.351
T23 Burn and corrosion of wrist and hand	0.649	0.351
S02.80 Fractures of other skull and facial bones (closed)	0.649	0.351
I27.2 Other secondary pulmonary hypertension	0.649	0.351
G43 Migraine	0.649	0.351
I51.1 Rupture of chordae tendineae, not elsewhere classified	0.649	0.351
M79.54 Residual foreign body in soft tissue (Hand)	0.648	0.352
E27.5 Adrenomedullary hyperfunction	0.648	0.352
E27.3 Drug-induced adrenocortical insufficiency	0.648	0.352
E27.0 Other adrenocortical overactivity	0.648	0.352
S06.7 Intracranial injury with prolonged coma	0.648	0.352
S06.1 Traumatic cerebral oedema	0.648	0.352
L27 Dermatitis due to substances taken internally	0.646	0.354
M05 Seropositive rheumatoid arthritis	0.645	0.355
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.644	0.356
E27.9 Disorder of adrenal gland, unspecified	0.644	0.356
E53.9 Vitamin B deficiency, unspecified	0.643	0.356
E53.1 Pyridoxine deficiency	0.643	0.356
E53.0 Riboflavin deficiency	0.643	0.356
I51.6 Cardiovascular disease, unspecified	0.643	0.357
L89.1 Stage II decubitus ulcer	0.643	0.357
I42.7 Cardiomyopathy due to drugs and other external agents	0.642	0.358
I42.6 Alcoholic cardiomyopathy	0.642	0.358
I42.5 Other restrictive cardiomyopathy	0.642	0.358
I42.4 Endocardial fibroelastosis	0.642	0.358
I42.3 Endomyocardial (eosinophilic) disease	0.642	0.358
B85-B89 Pediculosis, acariasis and other infestations	0.642	0.358
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.642	0.358
A75-A79 Rickettsioses	0.642	0.358
A70-A74 Other diseases caused by chlamydiae	0.642	0.358
A65-A69 Other spirochaetal diseases	0.642	0.358
A20-A28 Certain zoonotic bacterial diseases	0.642	0.358
X45 Accidental poisoning by and exposure to alcohol	0.641	0.359
A80-A89 Viral infections of the central nervous system	0.641	0.359
S60 Superficial injury of wrist and hand	0.640	0.359
S82.40 Fracture of fibula alone (closed)	0.640	0.360
F33.8 Other recurrent depressive disorders	0.640	0.360
F33.4 Recurrent depressive disorder, currently in remission	0.640	0.360
F33.0 Recurrent depressive disorder, current episode mild	0.640	0.360
M79.0 Rheumatism, unspecified	0.640	0.360
B65-B83 Helminthiases	0.639	0.361
H90 Conductive and sensorineural hearing loss	0.638	0.362
M60 Myositis	0.638	0.362
M79.2 Neuralgia and neuritis, unspecified	0.638	0.362

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations