TreeWAS – Variant ID: rs4895441

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
N99.3 Prolapse of vaginal vault after hysterectomy	0.031	0.969	0.000
N73.9 Female pelvic inflammatory disease, unspecified	0.020	0.980	0.000
K35.0 Acute appendicitis with generalised peritonitis	0.014	0.986	0.000
M24.41 Recurrent dislocation and subluxation of joint (Shoulder region)	0.000	0.989	0.010
N73 Other female pelvic inflammatory diseases	0.010	0.990	0.000
D75.1 Secondary polycythaemia	0.000	0.991	0.009
N73.5 Female pelvic peritonitis, unspecified	0.009	0.991	0.000
N99 Postprocedural disorders of genito-urinary system, not elsewhere classified	0.009	0.991	0.000
N73.0 Acute parametritis and pelvic cellulitis	0.008	0.992	0.000
N73.8 Other specified female pelvic inflammatory diseases	0.008	0.992	0.000
M24.4 Recurrent dislocation and subluxation of joint	0.000	0.992	0.008
N73.4 Female chronic pelvic peritonitis	0.007	0.993	0.000
N73.3 Female acute pelvic peritonitis	0.007	0.993	0.000
N73.2 Unspecified parametritis and pelvic cellulitis	0.007	0.993	0.000
N99.1 Postprocedural urethral stricture	0.007	0.993	0.000
M24.44 Recurrent dislocation and subluxation of joint (Hand)	0.000	0.993	0.007
N99.9 Postprocedural disorder of genito-urinary system, unspecified	0.007	0.993	0.000
Y83.3 Surgical operation with formation of external stoma	0.007	0.993	0.000
N99.5 Malfunction of external stoma of urinary tract	0.006	0.993	0.000
N73.1 Chronic parametritis and pelvic cellulitis	0.006	0.994	0.000
M24.47 Recurrent dislocation and subluxation of joint (Ankle and foot)	0.000	0.994	0.006
M24.45 Recurrent dislocation and subluxation of joint (Pelvic region and thigh)	0.000	0.994	0.006
M24.49 Recurrent dislocation and subluxation of joint (Site unspecified)	0.000	0.994	0.006
M24.48 Recurrent dislocation and subluxation of joint (Other)	0.000	0.994	0.006
M24.46 Recurrent dislocation and subluxation of joint (Lower leg)	0.000	0.994	0.006
M24.43 Recurrent dislocation and subluxation of joint (Forearm)	0.000	0.994	0.006
M24.42 Recurrent dislocation and subluxation of joint (Upper arm)	0.000	0.994	0.006
M24.40 Recurrent dislocation and subluxation of joint (Multiple sites)	0.000	0.994	0.006
H90.5 Sensorineural hearing loss, unspecified	0.006	0.994	0.000
N99.0 Postprocedural renal failure	0.006	0.994	0.000
N99.4 Postprocedural pelvic peritoneal adhesions	0.005	0.995	0.000
H90.3 Sensorineural hearing loss, bilateral	0.005	0.995	0.000
G25.0 Essential tremor	0.005	0.995	0.000
N99.2 Postprocedural adhesions of vagina	0.005	0.995	0.000
H90 Conductive and sensorineural hearing loss	0.005	0.995	0.000
M24.16 Other articular cartilage disorders (Lower leg)	0.000	0.995	0.005
M24.1 Other articular cartilage disorders	0.000	0.996	0.004
H90.4 Sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side	0.004	0.996	0.000
C69.9 Eye, unspecified	0.000	0.996	0.004
M24.15 Other articular cartilage disorders (Pelvic region and thigh)	0.000	0.996	0.004
I27.0 Primary pulmonary hypertension	0.004	0.996	0.000
H90.7 Mixed conductive and sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side	0.004	0.996	0.000
C69 Malignant neoplasm of eye and adnexa	0.000	0.996	0.004
D11.0 Parotid gland	0.000	0.996	0.004
N99.8 Other postprocedural disorders of genito-urinary system	0.004	0.996	0.000
S10.9 Superficial injury of neck, part unspecified	0.004	0.996	0.000
G25 Other extrapyramidal and movement disorders	0.004	0.996	0.000
C69.3 Choroid	0.000	0.996	0.004
M24.11 Other articular cartilage disorders (Shoulder region)	0.000	0.996	0.004
G25.2 Other specified forms of tremor	0.004	0.996	0.000
S12.70 Multiple fractures of cervical spine (closed)	0.004	0.996	0.000
N99-N99 Other disorders of the genitourinary system	0.004	0.996	0.000
S02.30 Fracture of orbital floor (closed)	0.004	0.996	0.000
N85.8 Other specified noninflammatory disorders of uterus	0.000	0.996	0.004
M24.13 Other articular cartilage disorders (Forearm)	0.000	0.996	0.004
Z57.5 Occupational exposure to toxic agents in other industries	0.003	0.996	0.000
M19.09 Primary arthrosis of other joints (Site unspecified)	0.003	0.997	0.000
N75.1 Abscess of Bartholin's gland	0.003	0.997	0.000
M24.19 Other articular cartilage disorders (Site unspecified)	0.000	0.997	0.003
M24.18 Other articular cartilage disorders (Other)	0.000	0.997	0.003
M24.17 Other articular cartilage disorders (Ankle and foot)	0.000	0.997	0.003
M24.14 Other articular cartilage disorders (Hand)	0.000	0.997	0.003
M24.12 Other articular cartilage disorders (Upper arm)	0.000	0.997	0.003
M24.10 Other articular cartilage disorders (Multiple sites)	0.000	0.997	0.003
H90.2 Conductive hearing loss, unspecified	0.003	0.997	0.000
D50.8 Other iron deficiency anaemias	0.000	0.997	0.003
G25.1 Drug-induced tremor	0.003	0.997	0.000
G25.9 Extrapyramidal and movement disorder, unspecified	0.003	0.997	0.000
S12.7 Multiple fractures of cervical spine	0.003	0.997	0.000
H90.8 Mixed conductive and sensorineural hearing loss, unspecified	0.003	0.997	0.000
C69.0 Conjunctiva	0.000	0.997	0.003
S10 Superficial injury of neck	0.003	0.997	0.000
R04.0 Epistaxis	0.000	0.997	0.003
H90.6 Mixed conductive and sensorineural hearing loss, bilateral	0.003	0.997	0.000
Y45.1 Salicylates	0.003	0.997	0.000
G25.3 Myoclonus	0.003	0.997	0.000
N71 Inflammatory disease of uterus, except cervix	0.003	0.997	0.000
C69.6 Orbit	0.000	0.997	0.003
G91.9 Hydrocephalus, unspecified	0.000	0.997	0.003
M24 Other specific joint derangements	0.000	0.997	0.003
S12 Fracture of neck	0.003	0.997	0.000
N70-N77 Inflammatory diseases of female pelvic organs	0.003	0.997	0.000
C69.8 Overlapping lesion of eye and adnexa	0.000	0.997	0.003
C69.5 Lachrymal gland and duct	0.000	0.997	0.003
C69.4 Ciliary body	0.000	0.997	0.003
C69.2 Retina	0.000	0.997	0.003
C69.1 Cornea	0.000	0.997	0.003
I87.2 Venous insufficiency (chronic) (peripheral)	0.003	0.997	0.000
C71.2 Temporal lobe	0.000	0.997	0.003
I27 Other pulmonary heart diseases	0.003	0.997	0.000
M23.32 Other meniscus derangements (Posterior cruciate ligament or Posterior horn of medial meniscus)	0.000	0.997	0.003
N75 Diseases of Bartholin's gland	0.003	0.997	0.000
G25.6 Drug-induced tics and other tics of organic origin	0.003	0.997	0.000
G25.5 Other chorea	0.003	0.997	0.000
G25.4 Drug-induced chorea	0.003	0.997	0.000
C71 Malignant neoplasm of brain	0.000	0.997	0.003
S12.2 Fracture of other specified cervical vertebra	0.003	0.997	0.000
S12.20 Fracture of other specified cervical vertebra (closed)	0.003	0.997	0.000
G91.1 Obstructive hydrocephalus	0.000	0.997	0.003
I27.2 Other secondary pulmonary hypertension	0.003	0.997	0.000
G91 Hydrocephalus	0.000	0.997	0.003
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.000	0.997	0.003
S19 Other and unspecified injuries of neck	0.003	0.997	0.000
M25.62 Stiffness of joint, not elsewhere classified (Upper arm)	0.003	0.997	0.000
H90.0 Conductive hearing loss, bilateral	0.003	0.997	0.000
Q61.3 Polycystic kidney, unspecified	0.000	0.997	0.003
S02.3 Fracture of orbital floor	0.003	0.997	0.000
S19.9 Unspecified injury of neck	0.003	0.997	0.000
G96.1 Disorders of meninges, not elsewhere classified	0.000	0.997	0.003
N71.1 Chronic inflammatory disease of uterus	0.003	0.997	0.000
N71.0 Acute inflammatory disease of uterus	0.003	0.997	0.000
S91.0 Open wound of ankle	0.000	0.997	0.003
M19.98 Arthrosis, unspecified (Other)	0.003	0.997	0.000
D86.8 Sarcoidosis of other and combined sites	0.003	0.997	0.000
H90.1 Conductive hearing loss, unilateral with unrestricted hearing on the contralateral side	0.003	0.997	0.000
N89.5 Stricture and atresia of vagina	0.000	0.997	0.003
S10.1 Other and unspecified superficial injuries of throat	0.003	0.997	0.000
S91 Open wound of ankle and foot	0.000	0.997	0.003
S91.1 Open wound of toe(s) without damage to nail	0.000	0.997	0.003
R45.8 Other symptoms and signs involving emotional state	0.000	0.997	0.003
G37.9 Demyelinating disease of central nervous system, unspecified	0.003	0.997	0.000
N71.9 Inflammatory disease of uterus, unspecified	0.003	0.997	0.000
S91.3 Open wound of other parts of foot	0.000	0.997	0.003
G91.8 Other hydrocephalus	0.000	0.997	0.003
S10-S19 Injuries to the neck	0.003	0.997	0.000
M54.96 Dorsalgia, unspecified (Lumbar region)	0.000	0.997	0.003
H00.1 Chalazion	0.000	0.997	0.003
O42.0 Premature rupture of membranes, onset of labour within 24 hours	0.000	0.997	0.003
S19.8 Other specified injuries of neck	0.003	0.997	0.000
Y45.0 Opioids and related analgesics	0.003	0.997	0.000
N77 Vulvovaginal ulceration and inflammation in diseases classified elsewhere	0.003	0.997	0.000
R45.2 Unhappiness	0.000	0.997	0.003
S12.71 Multiple fractures of cervical spine (open)	0.002	0.997	0.000
M25.64 Stiffness of joint, not elsewhere classified (Hand)	0.003	0.997	0.000
S10.7 Multiple superficial injuries of neck	0.002	0.997	0.000
S10.0 Contusion of throat	0.002	0.997	0.000
M25.6 Stiffness of joint, not elsewhere classified	0.003	0.997	0.000
S72.30 Fracture of shaft of femur (closed)	0.000	0.997	0.003
M24.7 Protrusio acetabuli	0.000	0.997	0.003
R45 Symptoms and signs involving emotional state	0.000	0.997	0.003
Z50.7 Occupational therapy and vocational rehabilitation, not elsewhere classified	0.003	0.997	0.000
C71.1 Frontal lobe	0.000	0.997	0.003
D48.6 Breast	0.000	0.997	0.003
C71.8 Overlapping lesion of brain	0.000	0.997	0.002
S10.8 Superficial injury of other parts of neck	0.002	0.997	0.000
G96 Other disorders of central nervous system	0.000	0.997	0.003
R45.0 Nervousness	0.000	0.997	0.003
M24.9 Joint derangement, unspecified	0.000	0.997	0.002
S12.8 Fracture of other parts of neck	0.002	0.997	0.000
S12.0 Fracture of first cervical vertebra	0.002	0.997	0.000
C72 Malignant neoplasm of spinal cord, cranial nerves and other parts of central nervous system	0.000	0.997	0.002
N74 Female pelvic inflammatory disorders in diseases classified elsewhere	0.002	0.997	0.000
C71.0 Cerebrum, except lobes and ventricles	0.000	0.997	0.002
D89.1 Cryoglobulinaemia	0.002	0.997	0.000
I27.9 Pulmonary heart disease, unspecified	0.002	0.997	0.000
I27.1 Kyphoscoliotic heart disease	0.002	0.997	0.000
Y51.7 Beta-Adrenoreceptor antagonists, not elsewhere classified	0.003	0.997	0.000
C70 Malignant neoplasm of meninges	0.000	0.997	0.002
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.002	0.997	0.000
S92.40 Fracture of great toe (closed)	0.000	0.998	0.002
N75.9 Disease of Bartholin's gland, unspecified	0.002	0.998	0.000
N75.8 Other diseases of Bartholin's gland	0.002	0.998	0.000
D75 Other diseases of blood and blood-forming organs	0.000	0.998	0.002
C71.7 Brain stem	0.000	0.998	0.002
C71.6 Cerebellum	0.000	0.998	0.002
C71.5 Cerebral ventricle	0.000	0.998	0.002
S12.1 Fracture of second cervical vertebra	0.002	0.998	0.000
M25.63 Stiffness of joint, not elsewhere classified (Forearm)	0.002	0.998	0.000
S12.21 Fracture of other specified cervical vertebra (open)	0.002	0.998	0.000
R45.1 Restlessness and agitation	0.000	0.998	0.002
G96.0 Cerebrospinal fluid leak	0.000	0.998	0.002
M24.2 Disorder of ligament	0.000	0.998	0.002
C71.4 Occipital lobe	0.000	0.998	0.002
D89.2 Hypergammaglobulinaemia, unspecified	0.002	0.998	0.000
G91.3 Posttraumatic hydrocephalus, unspecified	0.000	0.998	0.002
G91.0 Communicating hydrocephalus	0.000	0.998	0.002
R45.6 Physical violence	0.000	0.998	0.002
M19.04 Primary arthrosis of other joints (Hand)	0.002	0.998	0.000
S02.90 Fracture of skull and facial bones, part unspecified (closed)	0.002	0.998	0.000
N77.1 Vaginitis, vulvitis and vulvovaginitis in infectious and parasitic diseases classified elsewhere	0.002	0.998	0.000
S19.7 Multiple injuries of neck	0.002	0.998	0.000
S11 Open wound of neck	0.002	0.998	0.000
D86.3 Sarcoidosis of skin	0.002	0.998	0.000
S12.9 Fracture of neck, part unspecified	0.002	0.998	0.000
M25.61 Stiffness of joint, not elsewhere classified (Shoulder region)	0.002	0.998	0.000
S02.31 Fracture of orbital floor (open)	0.002	0.998	0.000
S02.70 Multiple fractures involving skull and facial bones (closed)	0.002	0.998	0.000
M24.6 Ankylosis of joint	0.000	0.998	0.002
M25.66 Stiffness of joint, not elsewhere classified (Lower leg)	0.002	0.998	0.000
C71.3 Parietal lobe	0.000	0.998	0.002
G91.2 Normal-pressure hydrocephalus	0.000	0.998	0.002
G96.8 Other specified disorders of central nervous system	0.000	0.998	0.002
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified	0.000	0.998	0.002
M25.67 Stiffness of joint, not elsewhere classified (Ankle and foot)	0.002	0.998	0.000
D75.0 Familial erythrocytosis	0.000	0.998	0.002
D89.9 Disorder involving the immune mechanism, unspecified	0.002	0.998	0.000
S02.9 Fracture of skull and facial bones, part unspecified	0.002	0.998	0.000
S02.7 Multiple fractures involving skull and facial bones	0.002	0.998	0.000
S91.7 Multiple open wounds of ankle and foot	0.000	0.998	0.002
S91.2 Open wound of toe(s) with damage to nail	0.000	0.998	0.002
S02 Fracture of skull and facial bones	0.002	0.998	0.000
D89.0 Polyclonal hypergammaglobulinaemia	0.002	0.998	0.000
D86 Sarcoidosis	0.002	0.998	0.000
M24.23 Disorder of ligament (Forearm)	0.000	0.998	0.002
I45.8 Other specified conduction disorders	0.000	0.998	0.002
C72.0 Spinal cord	0.000	0.998	0.002
S17 Crushing injury of neck	0.002	0.998	0.000
S15 Injury of blood vessels at neck level	0.002	0.998	0.000
S18 Traumatic amputation at neck level	0.002	0.998	0.000
S16 Injury of muscle and tendon at neck level	0.002	0.998	0.000
N77.8 Vulvovaginal ulceration and inflammation in other diseases classified elsewhere	0.002	0.998	0.000
N77.0 Ulceration of vulva in infectious and parasitic diseases classified elsewhere	0.002	0.998	0.000
Q61 Cystic kidney disease	0.000	0.998	0.002
M24.75 Protrusio acetabuli-Pelvic/thigh	0.000	0.998	0.002
M25.76 Osteophyte (Lower leg)	0.000	0.998	0.002
Q61.2 Polycystic kidney, adult type	0.000	0.998	0.002
K35 Acute appendicitis	0.002	0.998	0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs	0.002	0.998	0.000
M25.69 Stiffness of joint, not elsewhere classified (Site unspecified)	0.002	0.998	0.000
M25.65 Stiffness of joint, not elsewhere classified (Pelvic region and thigh)	0.002	0.998	0.000
C70.0 Cerebral meninges	0.000	0.998	0.002
S93.0 Dislocation of ankle joint	0.000	0.998	0.002
M24.79 Protrusio acetabuli-Site unspec	0.000	0.998	0.002
M24.78 Protrusio acetabuli-Other	0.000	0.998	0.002
M24.77 Protrusio acetabuli-Ankle/foot	0.000	0.998	0.002
M24.76 Protrusio acetabuli-Lower leg	0.000	0.998	0.002
M24.74 Protrusio acetabuli-Hand	0.000	0.998	0.002
M24.73 Protrusio acetabuli-Forearm	0.000	0.998	0.002
M24.72 Protrusio acetabuli-Upper arm	0.000	0.998	0.002
M24.71 Protrusio acetabuli-Shldr region	0.000	0.998	0.002
M24.70 Protrusio acetabuli-Mult sites	0.000	0.998	0.002
R45.3 Demoralisation and apathy	0.000	0.998	0.002
I27.8 Other specified pulmonary heart diseases	0.002	0.998	0.000
S11.8 Open wound of other parts of neck	0.002	0.998	0.000
M24.27 Disorder of ligament (Ankle and foot)	0.000	0.998	0.002
M25.68 Stiffness of joint, not elsewhere classified (Other)	0.002	0.998	0.000
G96.9 Disorder of central nervous system, unspecified	0.000	0.998	0.002
M24.28 Disorder of ligament (Other)	0.000	0.998	0.002
M24.99 Joint derangement, unspecified (Site unspecified)	0.000	0.998	0.002
M24.98 Joint derangement, unspecified (Other)	0.000	0.998	0.002
M24.97 Joint derangement, unspecified (Ankle and foot)	0.000	0.998	0.002
M24.96 Joint derangement, unspecified (Lower leg)	0.000	0.998	0.002
M24.95 Joint derangement, unspecified (Pelvic region and thigh)	0.000	0.998	0.002
M24.94 Joint derangement, unspecified (Hand)	0.000	0.998	0.002
M24.93 Joint derangement, unspecified (Forearm)	0.000	0.998	0.002
M24.92 Joint derangement, unspecified (Upper arm)	0.000	0.998	0.002
M24.91 Joint derangement, unspecified (Shoulder region)	0.000	0.998	0.002
M24.90 Joint derangement, unspecified (Multiple sites)	0.000	0.998	0.002
S12.01 Fracture of first cervical vertebra (open)	0.002	0.998	0.000
S12.00 Fracture of first cervical vertebra (closed)	0.002	0.998	0.000
S12.81 Fracture of other parts of neck (open)	0.002	0.998	0.000
S12.80 Fracture of other parts of neck (closed)	0.002	0.998	0.000
C72.9 Central nervous system, unspecified	0.000	0.998	0.002
C72.8 Overlapping lesion of brain and other parts of central nervous system	0.000	0.998	0.002
C72.5 Other and unspecified cranial nerves	0.000	0.998	0.002
C72.4 Acoustic nerve	0.000	0.998	0.002
C72.3 Optic nerve	0.000	0.998	0.002
C72.2 Olfactory nerve	0.000	0.998	0.002
C72.1 Cauda equina	0.000	0.998	0.002
N74.8 Female pelvic inflammatory disorders in other diseases classified elsewhere	0.002	0.998	0.000
N74.4 Female chlamydial pelvic inflammatory disease	0.002	0.998	0.000
N74.3 Female gonococcal pelvic inflammatory disease	0.002	0.998	0.000
N74.2 Female syphilitic pelvic inflammatory disease	0.002	0.998	0.000
N74.1 Female tuberculous pelvic inflammatory disease	0.002	0.998	0.000
N74.0 Tuberculous infection of cervix uteri	0.002	0.998	0.000
C71.9 Brain, unspecified	0.000	0.998	0.002
S02.8 Fractures of other skull and facial bones	0.002	0.998	0.000
C70.9 Meninges, unspecified	0.000	0.998	0.002
C70.1 Spinal meninges	0.000	0.998	0.002
D89.3 Immune reconstitution syndrome	0.002	0.998	0.000
G47.0 Disorders of initiating and maintaining sleep [insomnias]	0.000	0.998	0.002
Q61.0 Congenital single renal cyst	0.000	0.998	0.002
R45.4 Irritability and anger	0.000	0.998	0.002
M24.66 Ankylosis of joint (Lower leg)	0.000	0.998	0.002
G40.9 Epilepsy, unspecified	0.000	0.998	0.002
Y45.4 Antirheumatics	0.002	0.998	0.000
S14 Injury of nerves and spinal cord at neck level	0.002	0.998	0.000
S12.11 Fracture of second cervical vertebra (open)	0.002	0.998	0.000
M24.29 Disorder of ligament (Site unspecified)	0.000	0.998	0.002
M24.25 Disorder of ligament (Pelvic region and thigh)	0.000	0.998	0.002
M24.22 Disorder of ligament (Upper arm)	0.000	0.998	0.002
M24.20 Disorder of ligament (Multiple sites)	0.000	0.998	0.002
D86.9 Sarcoidosis, unspecified	0.002	0.998	0.000
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified	0.002	0.998	0.000
M25.60 Stiffness of joint, not elsewhere classified (Multiple sites)	0.002	0.998	0.000
M24.0 Loose body in joint	0.000	0.998	0.002
R45.5 Hostility	0.000	0.998	0.002
Q61.5 Medullary cystic kidney	0.000	0.998	0.002
S11.7 Multiple open wounds of neck	0.002	0.998	0.000
S11.2 Open wound involving pharynx and cervical oesophagus	0.002	0.998	0.000
S11.1 Open wound involving thyroid gland	0.002	0.998	0.000
S11.0 Open wound involving larynx and trachea	0.002	0.998	0.000
M24.69 Ankylosis of joint (Site unspecified)	0.000	0.998	0.002
M24.68 Ankylosis of joint (Other)	0.000	0.998	0.002
M24.65 Ankylosis of joint (Pelvic region and thigh)	0.000	0.998	0.002
M24.64 Ankylosis of joint (Hand)	0.000	0.998	0.002
M24.63 Ankylosis of joint (Forearm)	0.000	0.998	0.002
M24.62 Ankylosis of joint (Upper arm)	0.000	0.998	0.002
M24.61 Ankylosis of joint (Shoulder region)	0.000	0.998	0.002
M24.60 Ankylosis of joint (Multiple sites)	0.000	0.998	0.002
M79.29 Neuralgia and neuritis, unspecified (Site unspecified)	0.000	0.998	0.002
S12.91 Fracture of neck, part unspecified (open)	0.002	0.998	0.000
S92.4 Fracture of great toe	0.000	0.998	0.002
M24.39 Pathological dislocation and subluxation of joint, not elsewhere classified (Site unspecified)	0.000	0.998	0.002
M24.38 Pathological dislocation and subluxation of joint, not elsewhere classified (Other)	0.000	0.998	0.002
M24.36 Pathological dislocation and subluxation of joint, not elsewhere classified (Lower leg)	0.000	0.998	0.002
M24.35 Pathological dislocation and subluxation of joint, not elsewhere classified (Pelvic region and thigh)	0.000	0.998	0.002
M24.34 Pathological dislocation and subluxation of joint, not elsewhere classified (Hand)	0.000	0.998	0.002
M24.33 Pathological dislocation and subluxation of joint, not elsewhere classified (Forearm)	0.000	0.998	0.002
M24.32 Pathological dislocation and subluxation of joint, not elsewhere classified (Upper arm)	0.000	0.998	0.002
M24.31 Pathological dislocation and subluxation of joint, not elsewhere classified (Shoulder region)	0.000	0.998	0.002
M24.30 Pathological dislocation and subluxation of joint, not elsewhere classified (Multiple sites)	0.000	0.998	0.002
S02.0 Fracture of vault of skull	0.002	0.998	0.000
S11.9 Open wound of neck, part unspecified	0.002	0.998	0.000
S02.91 Fracture of skull and facial bones, part unspecified (open)	0.002	0.998	0.000
Q53.1 Undescended testicle, unilateral	0.000	0.998	0.002
S70.0 Contusion of hip	0.002	0.998	0.000
S02.71 Multiple fractures involving skull and facial bones (open)	0.002	0.998	0.000
S02.80 Fractures of other skull and facial bones (closed)	0.002	0.998	0.000
S12.10 Fracture of second cervical vertebra (closed)	0.002	0.998	0.000
B35.1 Tinea unguium	0.002	0.998	0.000
R45.7 State of emotional shock and stress, unspecified	0.000	0.998	0.002
G25.8 Other specified extrapyramidal and movement disorders	0.002	0.998	0.000
Q61.9 Cystic kidney disease, unspecified	0.000	0.998	0.002
Y45.2 Propionic acid derivatives	0.002	0.998	0.000
M24.21 Disorder of ligament (Shoulder region)	0.000	0.998	0.002
S02.2 Fracture of nasal bones	0.002	0.998	0.000
S15.9 Injury of unspecified blood vessel at neck level	0.002	0.998	0.000
S15.8 Injury of other blood vessels at neck level	0.002	0.998	0.000
S15.7 Injury of multiple blood vessels at neck level	0.002	0.998	0.000
S15.3 Injury of internal jugular vein	0.002	0.998	0.000
S15.2 Injury of external jugular vein	0.002	0.998	0.000
S15.1 Injury of vertebral artery	0.002	0.998	0.000
S15.0 Injury of carotid artery	0.002	0.998	0.000
S17.9 Crushing injury of neck, part unspecified	0.002	0.998	0.000
S17.8 Crushing injury of other parts of neck	0.002	0.998	0.000
S17.0 Crushing injury of larynx and traches	0.002	0.998	0.000
Y45.8 Other analgesics and antipyretics	0.002	0.998	0.000
N61 Inflammatory disorders of breast	0.002	0.998	0.000
D75.2 Essential thrombocytosis	0.000	0.998	0.002
Q61.8 Other cystic kidney diseases	0.000	0.998	0.002
Q61.1 Polycystic kidney, infantile type	0.000	0.998	0.002
K35.3 Acute appendicitis with localized peritonitis	0.002	0.998	0.000
S02.1 Fracture of base of skull	0.002	0.998	0.000
D86.1 Sarcoidosis of lymph nodes	0.002	0.998	0.000
M16.0 Primary coxarthrosis, bilateral	0.000	0.998	0.002
Y52.4 Angiotensin-converting-enzyme inhibitors	0.002	0.998	0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified	0.000	0.998	0.002
N72 Inflammatory disease of cervix uteri	0.002	0.998	0.000
S02.4 Fracture of malar and maxillary bones	0.002	0.998	0.000
T91.8 Sequelae of other specified injuries of neck and trunk	0.002	0.998	0.000
M41.86 Other forms of scoliosis (Lumbar region)	0.002	0.998	0.000
G97.0 Cerebrospinal fluid leak from spinal puncture	0.000	0.998	0.002
M13.94 Arthritis, unspecified (Hand)	0.000	0.998	0.002
M24.8 Other specific joint derangements, not elsewhere classified	0.000	0.998	0.002
T46.4 Angiotensin-converting-enzyme inhibitors	0.000	0.998	0.002
S12.90 Fracture of neck, part unspecified (closed)	0.002	0.998	0.000
G37.8 Other specified demyelinating diseases of central nervous system	0.002	0.998	0.000
I26 Pulmonary embolism	0.002	0.998	0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.002	0.998	0.000
M24.01 Loose body in joint (Shoulder region)	0.000	0.998	0.002
S02.81 Fractures of other skull and facial bones (open)	0.002	0.998	0.000
D75.9 Disease of blood and blood-forming organs, unspecified	0.000	0.998	0.002
G37 Other demyelinating diseases of central nervous system	0.002	0.998	0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level	0.000	0.998	0.002
Q61.4 Renal dysplasia	0.000	0.998	0.002
S02.5 Fracture of tooth	0.002	0.998	0.000
S14.1 Other and unspecified injuries of cervical spinal cord	0.002	0.998	0.000
G11.9 Hereditary ataxia, unspecified	0.000	0.998	0.002
I45.5 Other specified heart block	0.000	0.998	0.002
S14.6 Injury of other and unspecified nerves of neck	0.002	0.998	0.000
S14.5 Injury of cervical sympathetic nerves	0.002	0.998	0.000
S14.4 Injury of peripheral nerves of neck	0.002	0.998	0.000
S14.2 Injury of nerve root of cervical spine	0.002	0.998	0.000
S14.0 Concussion and oedema of cervical spinal cord	0.002	0.998	0.000
M24.37 Pathological dislocation and subluxation of joint, not elsewhere classified (Ankle and foot)	0.000	0.998	0.001
N75.0 Cyst of Bartholin's gland	0.002	0.998	0.000
M24.09 Loose body in joint (Site unspecified)	0.000	0.998	0.002
M24.08 Loose body in joint (Other)	0.000	0.998	0.002
M24.05 Loose body in joint (Pelvic region and thigh)	0.000	0.998	0.002
M24.04 Loose body in joint (Hand)	0.000	0.998	0.002
M24.00 Loose body in joint (Multiple sites)	0.000	0.998	0.002
S02.11 Fracture of base of skull (open)	0.002	0.998	0.000
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes	0.002	0.998	0.000
G97.8 Other postprocedural disorders of nervous system	0.000	0.998	0.002
Y52.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.002	0.998	0.000
G90-G99 Other disorders of the nervous system	0.000	0.998	0.002
S02.00 Fracture of vault of skull (closed)	0.002	0.998	0.000
I26.9 Pulmonary embolism without mention of acute cor pulmonale	0.002	0.998	0.000
K35.2 Acute appendicitis with generalized peritonitis	0.002	0.998	0.000
M24.24 Disorder of ligament (Hand)	0.000	0.998	0.001
S02.01 Fracture of vault of skull (open)	0.001	0.998	0.000
S02.20 Fracture of nasal bones (closed)	0.002	0.998	0.000
S92 Fracture of foot, except ankle	0.000	0.998	0.002
M24.26 Disorder of ligament (Lower leg)	0.000	0.998	0.001
I26.0 Pulmonary embolism with mention of acute cor pulmonale	0.002	0.998	0.000
T86.0 Bone-marrow transplant rejection	0.002	0.998	0.000
S90-S99 Injuries to the ankle and foot	0.000	0.998	0.002
M24.06 Loose body in joint-Lower leg	0.000	0.998	0.001
M24.67 Ankylosis of joint (Ankle and foot)	0.000	0.998	0.001
M24.84 Other specific joint derangements, not elsewhere classified (Hand)	0.000	0.998	0.002
C22.0 Liver cell carcinoma	0.002	0.998	0.000
Y52.2 Other antidysrhythmic drugs, not elsewhere classified	0.002	0.998	0.000
D80-D89 Certain disorders involving the immune mechanism	0.002	0.998	0.000
B94.8 Sequelae of other specified infectious and parasitic diseases	0.002	0.998	0.000
F81.9 Developmental disorder of scholastic skills, unspecified	0.002	0.998	0.000
G47.9 Sleep disorder, unspecified	0.000	0.998	0.002
G97.1 Other reaction to spinal and lumbar puncture	0.000	0.998	0.002
J04.0 Acute laryngitis	0.000	0.998	0.002
M24.07 Loose body in joint (Ankle and foot)	0.000	0.998	0.002
M79.26 Neuralgia and neuritis, unspecified (Lower leg)	0.000	0.998	0.002
G97.9 Postprocedural disorder of nervous system, unspecified	0.000	0.998	0.001
G97.2 Intracranial hypotension following ventricular shunting	0.000	0.998	0.001
S92.7 Multiple fractures of foot	0.000	0.998	0.002
Y45.9 Analgesic, antipyretic and anti-inflammatory drug, unspecified	0.001	0.998	0.000
Y51 Drugs primarily affecting the autonomic nervous system	0.002	0.998	0.000
S02.41 Fracture of malar and maxillary bones (open)	0.001	0.998	0.000
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified	0.002	0.998	0.000
G95.1 Vascular myelopathies	0.000	0.998	0.002
R90.8 Other abnormal findings on diagnostic imaging of central nervous system	0.000	0.998	0.002
M24.89 Other specific joint derangements, not elsewhere classified (Site unspecified)	0.000	0.998	0.001
M24.88 Other specific joint derangements, not elsewhere classified (Other)	0.000	0.998	0.001
M24.82 Other specific joint derangements, not elsewhere classified (Upper arm)	0.000	0.998	0.001
M24.80 Other specific joint derangements, not elsewhere classified (Multiple sites)	0.000	0.998	0.001
M41.99 Scoliosis, unspecified (Site unspecified)	0.002	0.998	0.000
M41.97 Scoliosis, unspecified (Lumbosacral region)	0.002	0.998	0.000
S92.41 Fracture of great toe (open)	0.000	0.998	0.001
M24.5 Contracture of joint	0.001	0.998	0.001
Y45.5 4-Aminophenol derivatives	0.001	0.998	0.000
M24.83 Other specific joint derangements, not elsewhere classified (Forearm)	0.000	0.998	0.001
X41.9 Unspecified place	0.002	0.998	0.000
Y52.0 Cardiac-stimulant glycosides and drugs of similar action	0.001	0.998	0.000
G95 Other diseases of spinal cord	0.000	0.998	0.002
S13 Dislocation, sprain and strain of joints and ligaments at neck level	0.001	0.998	0.000
M41.98 Scoliosis, unspecified (Sacral and sacrococcygeal region)	0.001	0.998	0.000
M79.25 Neuralgia and neuritis, unspecified (Pelvic region and thigh)	0.000	0.998	0.001
S92.70 Multiple fractures of foot (closed)	0.000	0.998	0.001
G37.5 Concentric sclerosis [Balo]	0.001	0.998	0.000
G37.4 Subacute necrotising myelitis	0.001	0.998	0.000
G37.2 Central pontine myelinolysis	0.001	0.998	0.000
G37.1 Central demyelination of corpus callosum	0.001	0.998	0.000
G37.0 Diffuse sclerosis	0.001	0.998	0.000
R20.2 Paraesthesia of skin	0.000	0.998	0.002
S93.4 Sprain and strain of ankle	0.000	0.998	0.001
S93.6 Sprain and strain of other and unspecified parts of foot	0.000	0.998	0.001
S93.5 Sprain and strain of toe(s)	0.000	0.998	0.001
S93.2 Rupture of ligaments at ankle and foot level	0.000	0.998	0.001
D83 Common variable immunodeficiency	0.001	0.998	0.000
M24.03 Loose body in joint (Forearm)	0.000	0.998	0.001
M79.28 Neuralgia and neuritis, unspecified (Other)	0.000	0.998	0.001
S02.51 Fracture of tooth (open)	0.001	0.998	0.000
M79.2 Neuralgia and neuritis, unspecified	0.000	0.998	0.002
S02.6 Fracture of mandible	0.001	0.998	0.000
S93.3 Dislocation of other and unspecified parts of foot	0.000	0.998	0.001
T86.8 Failure and rejection of other transplanted organs and tissues	0.002	0.998	0.000
I28 Other diseases of pulmonary vessels	0.001	0.998	0.000
Y52 Agents primarily affecting the cardiovascular system	0.002	0.998	0.000
S02.21 Fracture of nasal bones (open)	0.001	0.998	0.000
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system	0.001	0.998	0.000
S14.3 Injury of brachial plexus	0.001	0.998	0.000
Y51.9 Other and unspecified drugs primarily affecting the autonomic nervous system	0.001	0.998	0.000
Y52.7 Peripheral vasodilators	0.001	0.998	0.000
E65 Localised adiposity	0.000	0.998	0.001
G92 Toxic encephalopathy	0.000	0.998	0.001
M24.87 Other specific joint derangements, not elsewhere classified (Ankle and foot)	0.000	0.999	0.001
M24.81 Other specific joint derangements, not elsewhere classified (Shoulder region)	0.000	0.999	0.001
D83.9 Common variable immunodeficiency, unspecified	0.001	0.999	0.000
S92.9 Fracture of foot, unspecified	0.000	0.999	0.001
Z44.3 Fitting and adjustment of external breast prosthesis	0.000	0.999	0.001
S98 Traumatic amputation of ankle and foot	0.000	0.999	0.001
S97 Crushing injury of ankle and foot	0.000	0.999	0.001
S95 Injury of blood vessels at ankle and foot level	0.000	0.999	0.001
S94 Injury of nerves at ankle and foot level	0.000	0.999	0.001
D86.0 Sarcoidosis of lung	0.001	0.999	0.000
F50.0 Anorexia nervosa	0.001	0.999	0.000
G62.8 Other specified polyneuropathies	0.001	0.999	0.000
G95.0 Syringomyelia and syringobulbia	0.000	0.999	0.001
I45.2 Bifascicular block	0.001	0.999	0.000
R19.0 Intra-abdominal and pelvic swelling, mass and lump	0.001	0.999	0.000
S72.3 Fracture of shaft of femur	0.000	0.999	0.001
S92.2 Fracture of other tarsal bone(s)	0.000	0.999	0.001
Z04.5 Examination and observation following other inflicted injury	0.001	0.999	0.000
M24.57 Contracture of joint (Ankle and foot)	0.001	0.999	0.000
D48.7 Other specified sites	0.000	0.999	0.001
I28.9 Disease of pulmonary vessels, unspecified	0.001	0.999	0.000
J31.0 Chronic rhinitis	0.001	0.999	0.000
K22.9 Disease of oesophagus, unspecified	0.001	0.999	0.000
M50.0 Cervical disk disorder with myelopathy	0.000	0.999	0.001
D81 Combined immunodeficiencies	0.001	0.999	0.000
S96 Injury of muscle and tendon at ankle and foot level	0.000	0.999	0.001
S02.40 Fracture of malar and maxillary bones (closed)	0.001	0.999	0.000
M41.8 Other forms of scoliosis	0.001	0.999	0.000
S92.1 Fracture of talus	0.000	0.999	0.001
Y49.0 Tricyclic and tetracyclic antidepressants	0.001	0.999	0.000
Y51.8 Centrally acting and adrenergic-neuron-blocking agents, not elsewhere classified	0.001	0.999	0.000
Y51.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.001	0.999	0.000
Y51.2 Ganglionic blocking drugs, not elsewhere classified	0.001	0.999	0.000
Y51.1 Other parasympathomimetics [cholinergics]	0.001	0.999	0.000
Y51.0 Anticholinesterase agents	0.001	0.999	0.000
Y53.1 Other antacids and anti-gastric-secretion drugs	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations