TreeWAS – Variant ID: rs4898641

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
C92.0 Acute myeloid leukaemia	0.008	0.992	0.000
C92 Myeloid leukaemia	0.007	0.993	0.000
C92.1 Chronic myeloid leukaemia	0.006	0.994	0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.006	0.994	0.000
H33.3 Retinal breaks without detachment	0.000	0.994	0.006
C82 Follicular [nodular] non-Hodgkin's lymphoma	0.006	0.994	0.000
C82.1 Mixed small cleaved and large cell, follicular	0.005	0.995	0.000
C92.9 Myeloid leukaemia, unspecified	0.005	0.995	0.000
C92.8 Acute myeloid leukaemia with multilineage dysplasia	0.005	0.995	0.000
C92.7 Other myeloid leukaemia	0.005	0.995	0.000
C92.6 Acute myeloid leukaemia with 11q23-abnormality	0.005	0.995	0.000
C92.5 Acute myelomonocytic leukaemia	0.005	0.995	0.000
C92.4 Acute promyelocytic leukaemia	0.005	0.995	0.000
C92.3 Myeloid sarcoma	0.005	0.995	0.000
C92.2 Subacute myeloid leukaemia	0.005	0.995	0.000
C83 Diffuse non-Hodgkin's lymphoma	0.005	0.995	0.000
C81 Hodgkin's disease	0.005	0.995	0.000
K35.0 Acute appendicitis with generalised peritonitis	0.005	0.995	0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma	0.005	0.995	0.000
C83.3 Large cell (diffuse)	0.005	0.995	0.000
C82.9 Follicular non-Hodgkin's lymphoma, unspecified	0.005	0.995	0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue	0.004	0.996	0.000
C95 Leukaemia of unspecified cell type	0.004	0.996	0.000
C94 Other leukaemias of specified cell type	0.004	0.996	0.000
C93 Monocytic leukaemia	0.004	0.996	0.000
C88 Malignant immunoproliferative diseases	0.004	0.996	0.000
C86 Other specified types of T/NK-cell lymphoma	0.004	0.996	0.000
C84 Peripheral and cutaneous T-cell lymphomas	0.004	0.996	0.000
K35.1 Acute appendicitis with peritoneal abscess	0.004	0.996	0.000
C82.7 Other types of follicular non-Hodgkin's lymphoma	0.004	0.996	0.000
C82.6 Cutaneous follicle centre lymphoma	0.004	0.996	0.000
C82.5 Diffuse follicle centre lymphoma	0.004	0.996	0.000
C82.4 Follicular lymphoma grade IIIb	0.004	0.996	0.000
C82.3 Follicular lymphoma grade IIIa	0.004	0.996	0.000
C82.2 Large cell, follicular	0.004	0.996	0.000
C82.0 Small cleaved cell, follicular	0.004	0.996	0.000
C81.1 Nodular sclerosis	0.004	0.996	0.000
C91 Lymphoid leukaemia	0.004	0.996	0.000
T78.4 Allergy, unspecified	0.004	0.996	0.000
T78 Adverse effects, not elsewhere classified	0.004	0.996	0.000
S06.50 Traumatic subdural haemorrhage (without open intracranial wound)	0.004	0.996	0.000
C85.7 Other specified types of non-Hodgkin's lymphoma	0.004	0.996	0.000
S42.10 Fracture of scapula (closed)	0.004	0.996	0.000
C81.9 Hodgkin's disease, unspecified	0.004	0.996	0.000
C83.8 Other types of diffuse non-Hodgkin's lymphoma	0.004	0.996	0.000
C83.9 Diffuse non-Hodgkin's lymphoma, unspecified	0.004	0.996	0.000
C83.7 Burkitt's tumour	0.004	0.996	0.000
C83.6 Undifferentiated (diffuse)	0.004	0.996	0.000
C83.5 Lymphoblastic (diffuse)	0.004	0.996	0.000
C83.4 Immunoblastic (diffuse)	0.004	0.996	0.000
C83.2 Mixed small and large cell (diffuse)	0.004	0.996	0.000
C83.1 Small cleaved cell (diffuse)	0.004	0.996	0.000
K35 Acute appendicitis	0.004	0.996	0.000
C81.7 Other Hodgkin's disease	0.004	0.996	0.000
C81.4 Lymphocyte-rich classical Hodgkin lymphoma	0.004	0.996	0.000
C81.3 Lymphocytic depletion	0.004	0.996	0.000
C81.2 Mixed cellularity	0.004	0.996	0.000
C81.0 Lymphocytic predominance	0.004	0.996	0.000
C83.0 Small cell (diffuse)	0.004	0.996	0.000
S06.5 Traumatic subdural haemorrhage	0.004	0.996	0.000
C91.4 Hairy-cell leukaemia	0.004	0.996	0.000
T78.0 Anaphylactic shock due to adverse food reaction	0.004	0.996	0.000
S06 Intracranial injury	0.004	0.996	0.000
D89.2 Hypergammaglobulinaemia, unspecified	0.004	0.996	0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type	0.004	0.996	0.000
C85.2 Mediastinal (thymic) large B-cell lymphoma	0.003	0.996	0.000
C85.0 Lymphosarcoma	0.003	0.996	0.000
S42.1 Fracture of scapula	0.004	0.996	0.000
T78.3 Angioneurotic oedema	0.004	0.996	0.000
A41.9 Septicaemia, unspecified	0.004	0.996	0.000
T66-T78 Other and unspecified effects of external causes	0.003	0.996	0.000
C90 Multiple myeloma and malignant plasma cell neoplasms	0.003	0.996	0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.003	0.996	0.000
D80-D89 Certain disorders involving the immune mechanism	0.003	0.997	0.000
C84.9 Mature T/NK-cell lymphoma, unspecified	0.003	0.997	0.000
C84.8 Cutaneous T-cell lymphoma, unspecified	0.003	0.997	0.000
C84.7 Anaplastic large cell lymphoma, ALK-negative	0.003	0.997	0.000
C84.6 Anaplastic large cell lymphoma, ALK-positive	0.003	0.997	0.000
C84.5 Other and unspecified T-cell lymphomas	0.003	0.997	0.000
C84.4 Peripheral T-cell lymphoma	0.003	0.997	0.000
C84.3 Lymphoepithelioid lymphoma	0.003	0.997	0.000
C84.2 T-zone lymphoma	0.003	0.997	0.000
C84.1 Sezary's diease	0.003	0.997	0.000
C84.0 Mycosis fungoides	0.003	0.997	0.000
C85.1 B-cell lymphoma, unspecified	0.003	0.997	0.000
C86.6 Primary cutaneous CD30-positive T-cell proliferations	0.003	0.997	0.000
C86.5 Angioimmunoblastic T-cell lymphoma	0.003	0.997	0.000
C86.4 Blastic NK-cell lymphoma	0.003	0.997	0.000
C86.3 Subcutaneous panniculitis-like T-cell lymphoma	0.003	0.997	0.000
C86.2 Enteropathy-type (intestinal) T-cell lymphoma	0.003	0.997	0.000
C86.1 Hepatosplenic T-cell lymphoma	0.003	0.997	0.000
C86.0 Extranodal NK/T-cell lymphoma, nasal type	0.003	0.997	0.000
C88.9 Malignant immunoproliferative disease, unspecified	0.003	0.997	0.000
C88.7 Other malignant immunoproliferative diseases	0.003	0.997	0.000
C88.4 Extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue [MALT-lymphoma]	0.003	0.997	0.000
C88.3 Immunoproliferative small intestinal disease	0.003	0.997	0.000
C88.2 Gamma heavy chain disease	0.003	0.997	0.000
C88.1 Alpha heavy chain disease	0.003	0.997	0.000
C88.0 Waldenstrom's macroglobulinaemia	0.003	0.997	0.000
C93.9 Monocytic leukaemia, unspecified	0.003	0.997	0.000
C93.7 Other monocytic leukaemia	0.003	0.997	0.000
C93.3 Juvenile myelomonocytic leukaemia	0.003	0.997	0.000
C93.2 Subacute monocytic leukaemia	0.003	0.997	0.000
C93.1 Chronic monocytic leukaemia	0.003	0.997	0.000
C93.0 Acute monocytic leukaemia	0.003	0.997	0.000
C94.7 Other specified leukaemias	0.003	0.997	0.000
C94.6 Myelodysplastic and myeloproliferative disease, not elsewhere classified	0.003	0.997	0.000
C94.5 Acute myelofibrosis	0.003	0.997	0.000
C94.4 Acute panmyelosis	0.003	0.997	0.000
C94.3 Mast cell leukaemia	0.003	0.997	0.000
C94.2 Acute megakaryoblastic leukaemia	0.003	0.997	0.000
C94.1 Chronic erythraemia	0.003	0.997	0.000
C94.0 Acute erythraemia and erythroleukaemia	0.003	0.997	0.000
C95.9 Leukaemia, unspecified	0.003	0.997	0.000
C95.7 Other leukaemia of unspecified cell type	0.003	0.997	0.000
C95.2 Subacute leukaemia of unspecified cell type	0.003	0.997	0.000
C95.1 Chronic leukaemia of unspecified cell type	0.003	0.997	0.000
C95.0 Acute leukaemia of unspecified cell type	0.003	0.997	0.000
C96.9 Malignant neoplasms of lymphoid, haematopoietic and related tissue, unspecified	0.003	0.997	0.000
C96.8 Histiocytic sarcoma	0.003	0.997	0.000
C96.7 Other specified malignant neoplasms of lymphoid, haematopoietic and related tissue	0.003	0.997	0.000
C96.6 Unifocal Langerhans-cell histiocytosis	0.003	0.997	0.000
C96.5 Multifocal and unisystemic Langerhans-cell histiocytosis	0.003	0.997	0.000
C96.4 Sarcoma of dendritic cells (accessory cells)	0.003	0.997	0.000
C96.3 True histiocytic lymphoma	0.003	0.997	0.000
C96.2 Malignant mast cell tumour	0.003	0.997	0.000
C96.1 Malignant histiocytosis	0.003	0.997	0.000
C96.0 Letterer-Siwe disease	0.003	0.997	0.000
K35.2 Acute appendicitis with generalized peritonitis	0.003	0.997	0.000
S40-S49 Injuries to the shoulder and upper arm	0.003	0.997	0.000
S42 Fracture of shoulder and upper arm	0.003	0.997	0.000
A41 Other septicaemia	0.003	0.997	0.000
S83.2 Tear of meniscus, current	0.003	0.997	0.000
C91.0 Acute lymphoblastic leukaemia	0.003	0.997	0.000
D86 Sarcoidosis	0.003	0.997	0.000
S00-S09 Injuries to the head	0.003	0.997	0.000
C91.9 Lymphoid leukaemia, unspecified	0.003	0.997	0.000
C91.8 Mature B-cell leukaemia Burkitt-type	0.003	0.997	0.000
C91.7 Other lymphoid leukaemia	0.003	0.997	0.000
C91.6 Prolymphocytic leukaemia of T-cell type	0.003	0.997	0.000
C91.5 Adult T-cell leukaemia	0.003	0.997	0.000
C91.3 Prolymphocytic leukaemia	0.003	0.997	0.000
C91.2 Subacute lymphocytic leukaemia	0.003	0.997	0.000
A41.8 Other specified septicaemia	0.003	0.997	0.000
T78.9 Adverse effect, unspecified	0.003	0.997	0.000
T78.8 Other adverse effects, not elsewhere classified	0.003	0.997	0.000
T78.1 Other adverse food reactions, not elsewhere classified	0.003	0.997	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.003	0.997	0.000
S06.2 Diffuse brain injury	0.003	0.997	0.000
S06.8 Other intracranial injuries	0.003	0.997	0.000
D73.0 Hyposplenism	0.003	0.997	0.000
S41 Open wound of shoulder and upper arm	0.003	0.997	0.000
S70-S79 Injuries to the hip and thigh	0.003	0.997	0.000
K35.3 Acute appendicitis with localized peritonitis	0.003	0.997	0.000
S06.0 Concussion	0.003	0.997	0.000
T78.2 Anaphylactic shock, unspecified	0.003	0.997	0.000
D86.0 Sarcoidosis of lung	0.003	0.997	0.000
S42.4 Fracture of lower end of humerus	0.003	0.997	0.000
S05 Injury of eye and orbit	0.003	0.997	0.000
A41.0 Septicaemia due to Staphylococcus aureus	0.003	0.997	0.000
D80 Immunodeficiency with predominantly antibody defects	0.003	0.997	0.000
S06.51 Traumatic subdural haemorrhage (with open intracranial wound)	0.003	0.997	0.000
A41.1 Septicaemia due to other specified staphylococcus	0.003	0.997	0.000
S00.8 Superficial injury of other parts of head	0.003	0.997	0.000
T20-T25 Burns and corrosions of external body surface, specified by site	0.003	0.997	0.000
H81.1 Benign paroxysmal vertigo	0.003	0.997	0.000
K35.8 Acute appendicitis, other and unspecified	0.003	0.997	0.000
D86.1 Sarcoidosis of lymph nodes	0.003	0.997	0.000
S06.9 Intracranial injury, unspecified	0.003	0.997	0.000
S06.7 Intracranial injury with prolonged coma	0.003	0.997	0.000
S06.4 Epidural haemorrhage	0.003	0.997	0.000
S06.1 Traumatic cerebral oedema	0.003	0.997	0.000
D73 Diseases of spleen	0.003	0.997	0.000
S00 Superficial injury of head	0.003	0.997	0.000
S42.11 Fracture of scapula (open)	0.003	0.997	0.000
S06.3 Focal brain injury	0.003	0.997	0.000
S42.40 Fracture of lower end of humerus (closed)	0.003	0.997	0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee	0.003	0.997	0.000
I47.2 Ventricular tachycardia	0.000	0.997	0.003
D70-D77 Other diseases of blood and blood-forming organs	0.003	0.997	0.000
S20-S29 Injuries to the thorax	0.003	0.997	0.000
S41.0 Open wound of shoulder	0.003	0.997	0.000
S50-S59 Injuries to the elbow and forearm	0.003	0.997	0.000
D89.9 Disorder involving the immune mechanism, unspecified	0.003	0.997	0.000
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified	0.003	0.997	0.000
D89.3 Immune reconstitution syndrome	0.003	0.997	0.000
D89.1 Cryoglobulinaemia	0.003	0.997	0.000
D89.0 Polyclonal hypergammaglobulinaemia	0.003	0.997	0.000
S06.6 Traumatic subarachnoid haemorrhage	0.003	0.997	0.000
S02 Fracture of skull and facial bones	0.003	0.997	0.000
T75 Effects of other external causes	0.003	0.997	0.000
T74 Maltreatment syndromes	0.003	0.997	0.000
T73 Effects of other deprivation	0.003	0.997	0.000
T70 Effects of air pressure and water pressure	0.003	0.997	0.000
T69 Other effects of reduced temperature	0.003	0.997	0.000
T67 Effects of heat and light	0.003	0.997	0.000
T71 Asphyxiation	0.003	0.997	0.000
T66 Unspecified effects of radiation	0.003	0.997	0.000
S10-S19 Injuries to the neck	0.003	0.997	0.000
C90.3 Solitary plasmacytoma	0.003	0.997	0.000
C90.2 Plasmacytoma, extramedullary	0.003	0.997	0.000
C90.1 Plasma cell leukaemia	0.003	0.997	0.000
D63.0 Anaemia in neoplastic disease	0.003	0.997	0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.003	0.997	0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.003	0.997	0.000
S06.20 Diffuse brain injury (without open intracranial wound)	0.003	0.997	0.000
S93.1 Dislocation of toe(s)	0.003	0.997	0.000
D84 Other immunodeficiencies	0.003	0.997	0.000
D83 Common variable immunodeficiency	0.003	0.997	0.000
D82 Immunodeficiency associated with other major defects	0.003	0.997	0.000
D81 Combined immunodeficiencies	0.003	0.997	0.000
S56 Injury of muscle and tendon at forearm level	0.003	0.997	0.000
D80.1 Nonfamilial hypogammaglobulinaemia	0.003	0.997	0.000
S79 Other and unspecified injuries of hip and thigh	0.003	0.997	0.000
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand	0.003	0.997	0.000
S40 Superficial injury of shoulder and upper arm	0.003	0.997	0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.003	0.997	0.000
S05.1 Contusion of eyeball and orbital tissues	0.003	0.997	0.000
D70 Agranulocytosis	0.003	0.997	0.000
S06.80 Other intracranial injuries (without open intracranial wound)	0.003	0.997	0.000
S48 Traumatic amputation of shoulder and upper arm	0.003	0.997	0.000
S46 Injury of muscle and tendon at shoulder and upper arm level	0.003	0.997	0.000
S45 Injury of blood vessels at shoulder and upper arm level	0.003	0.997	0.000
S44 Injury of nerves at shoulder and upper arm level	0.003	0.997	0.000
S47 Crushing injury of shoulder and upper arm	0.003	0.997	0.000
R01.1 Cardiac murmur, unspecified	0.000	0.997	0.003
S42.9 Fracture of shoulder girdle, part unspecified	0.003	0.997	0.000
S42.8 Fracture of other parts of shoulder and upper arm	0.003	0.997	0.000
S42.7 Multiple fractures of clavicle, scapula and humerus	0.003	0.997	0.000
T20 Burn and corrosion of head and neck	0.003	0.997	0.000
T68 Hypothermia	0.003	0.997	0.000
A41.4 Septicaemia due to anaerobes	0.003	0.997	0.000
A41.3 Septicaemia due to Haemophilus influenzae	0.003	0.997	0.000
A41.2 Septicaemia due to unspecified staphylococcus	0.003	0.997	0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.003	0.997	0.000
T79-T79 Certain early complications of trauma	0.003	0.997	0.000
D86.8 Sarcoidosis of other and combined sites	0.002	0.997	0.000
D86.3 Sarcoidosis of skin	0.002	0.997	0.000
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes	0.002	0.997	0.000
S05.8 Other injuries of eye and orbit	0.003	0.997	0.000
S08 Traumatic amputation of part of head	0.003	0.997	0.000
S07 Crushing injury of head	0.003	0.997	0.000
S04 Injury of cranial nerves	0.003	0.997	0.000
S03 Dislocation, sprain and strain of joints and ligaments of head	0.003	0.997	0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle	0.003	0.997	0.000
T58 Toxic effect of carbon monoxide	0.003	0.997	0.000
D63 Anaemia in chronic diseases classified elsewhere	0.003	0.997	0.000
S72 Fracture of femur	0.003	0.997	0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level	0.003	0.997	0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.003	0.997	0.000
S06.00 Concussion (without open intracranial wound)	0.002	0.997	0.000
S42.0 Fracture of clavicle	0.003	0.997	0.000
S56.8 Injury of other and unspecified muscles and tendons at forearm level	0.003	0.997	0.000
S49 Other and unspecified injuries of shoulder and upper arm	0.002	0.997	0.000
S00.1 Contusion of eyelid and periocular area	0.003	0.997	0.000
S70 Superficial injury of hip and thigh	0.003	0.997	0.000
T11 Other injuries of upper limb, level unspecified	0.002	0.997	0.000
S90-S99 Injuries to the ankle and foot	0.003	0.997	0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.003	0.997	0.000
S42.3 Fracture of shaft of humerus	0.002	0.997	0.000
T22.3 Burn of third degree of shoulder and upper limb, except wrist and hand	0.002	0.997	0.000
S80-S89 Injuries to the knee and lower leg	0.003	0.997	0.000
S41.1 Open wound of upper arm	0.002	0.997	0.000
S27 Injury of other and unspecified intrathoracic organs	0.002	0.997	0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis	0.003	0.997	0.000
D86.9 Sarcoidosis, unspecified	0.002	0.997	0.000
K65.9 Peritonitis, unspecified	0.003	0.997	0.000
S71 Open wound of hip and thigh	0.002	0.997	0.000
T63 Toxic effect of contact with venomous animals	0.002	0.997	0.000
D55-D59 Haemolytic anaemias	0.002	0.997	0.000
T33-T35 Frostbite	0.002	0.997	0.000
T26-T28 Burns and corrosions confined to eye and internal organs	0.002	0.997	0.000
T00-T07 Injuries involving multiple body regions	0.002	0.997	0.000
S06.21 Diffuse brain injury (with open intracranial wound)	0.002	0.997	0.000
S79.9 Unspecified injury of hip and thigh	0.002	0.997	0.000
T11.0 Superficial injury of upper limb, level unspecified	0.002	0.997	0.000
H33 Retinal detachments and breaks	0.000	0.997	0.003
T15-T19 Effects of foreign body entering through natural orifice	0.002	0.997	0.000
S06.81 Other intracranial injuries (with open intracranial wound)	0.002	0.997	0.000
S22 Fracture of rib(s), sternum and thoracic spine	0.002	0.997	0.000
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)	0.002	0.997	0.000
S52.60 Fracture of lower end of both ulna and radius (closed)	0.002	0.997	0.000
S72.4 Fracture of lower end of femur	0.002	0.997	0.000
S06.01 Concussion (with open intracranial wound)	0.002	0.998	0.000
S00.5 Superficial injury of lip and oral cavity	0.002	0.998	0.000
S41.8 Open wound of other and unspecified parts of shoulder girdle	0.002	0.998	0.000
S41.7 Multiple open wounds of shoulder and upper arm	0.002	0.998	0.000
S78 Traumatic amputation of hip and thigh	0.002	0.998	0.000
S77 Crushing injury of hip and thigh	0.002	0.998	0.000
S76 Injury of muscle and tendon at hip and thigh level	0.002	0.998	0.000
S75 Injury of blood vessels at hip and thigh level	0.002	0.998	0.000
S74 Injury of nerves at hip and thigh level	0.002	0.998	0.000
S73 Dislocation, sprain and strain of joint and ligaments of hip	0.002	0.998	0.000
S42.41 Fracture of lower end of humerus (open)	0.002	0.998	0.000
D59.1 Other autoimmune haemolytic anaemias	0.002	0.998	0.000
S05.9 Injury of eye and orbit, part unspecified	0.002	0.998	0.000
S05.7 Avulsion of eye	0.002	0.998	0.000
S05.6 Penetrating wound of eyeball without foreign body	0.002	0.998	0.000
S05.5 Penetrating wound of eyeball with foreign body	0.002	0.998	0.000
S05.4 Penetrating wound of orbit with or without foreign body	0.002	0.998	0.000
S05.3 Ocular laceration without prolapse or loss of intraocular tissue	0.002	0.998	0.000
S05.2 Ocular laceration and rupture with prolapse or loss of intraocular tissue	0.002	0.998	0.000
D59 Acquired haemolytic anaemia	0.002	0.998	0.000
D68 Other coagulation defects	0.002	0.998	0.000
D80.9 Immunodeficiency with predominantly antibody defects, unspecified	0.002	0.998	0.000
D80.8 Other immunodeficiencies with predominantly antibody defects	0.002	0.998	0.000
D80.7 Transient hypogammaglobulinaemia of infancy	0.002	0.998	0.000
D80.6 Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinaemia	0.002	0.998	0.000
D80.5 Immunodeficiency with increased immunoglobulin M [IgM]	0.002	0.998	0.000
D80.4 Selective deficiency of immunoglobulin M [IgM]	0.002	0.998	0.000
D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses	0.002	0.998	0.000
D80.2 Selective deficiency of immunoglobulin A [IgA]	0.002	0.998	0.000
D80.0 Hereditary hypogammaglobulinaemia	0.002	0.998	0.000
S02.9 Fracture of skull and facial bones, part unspecified	0.002	0.998	0.000
S05.0 Injury of conjunctiva and corneal abrasion without mention of foreign body	0.002	0.998	0.000
T20.2 Burn of second degree of head and neck	0.002	0.998	0.000
S72.40 Fracture of lower end of femur (closed)	0.002	0.998	0.000
S02.8 Fractures of other skull and facial bones	0.002	0.998	0.000
S02.5 Fracture of tooth	0.002	0.998	0.000
S02.2 Fracture of nasal bones	0.002	0.998	0.000
T63.4 Venom of other arthropods	0.002	0.998	0.000
T25 Burn and corrosion of ankle and foot	0.002	0.998	0.000
T24 Burn and corrosion of hip and lower limb, except ankle and foot	0.002	0.998	0.000
T23 Burn and corrosion of wrist and hand	0.002	0.998	0.000
T21 Burn and corrosion of trunk	0.002	0.998	0.000
S70.0 Contusion of hip	0.002	0.998	0.000
D68.0 Von Willebrand's disease	0.002	0.998	0.000
S22.4 Multiple fractures of ribs	0.002	0.998	0.000
S51 Open wound of forearm	0.002	0.998	0.000
D60-D64 Aplastic and other anaemias	0.002	0.998	0.000
S83.5 Sprain and strain involving (anterior)(posterior) cruciate ligament of knee	0.002	0.998	0.000
S19 Other and unspecified injuries of neck	0.002	0.998	0.000
S12 Fracture of neck	0.002	0.998	0.000
S06.11 Traumatic cerebral oedema (with open intracranial wound)	0.002	0.998	0.000
S06.10 Traumatic cerebral oedema (without open intracranial wound)	0.002	0.998	0.000
S06.41 Epidural haemorrhage (with open intracranial wound)	0.002	0.998	0.000
S06.40 Epidural haemorrhage (without open intracranial wound)	0.002	0.998	0.000
S06.71 Intracranial injury with prolonged coma (with open intracranial wound)	0.002	0.998	0.000
S06.70 Intracranial injury with prolonged coma (without open intracranial wound)	0.002	0.998	0.000
S06.91 Intracranial injury, unspecified (with open intracranial wound)	0.002	0.998	0.000
S06.90 Intracranial injury, unspecified (without open intracranial wound)	0.002	0.998	0.000
D73.9 Disease of spleen, unspecified	0.002	0.998	0.000
D73.8 Other diseases of spleen	0.002	0.998	0.000
D73.5 Infarction of spleen	0.002	0.998	0.000
D73.4 Cyst of spleen	0.002	0.998	0.000
D73.3 Abscess of spleen	0.002	0.998	0.000
D73.2 Chronic congestive splenomegaly	0.002	0.998	0.000
D73.1 Hypersplenism	0.002	0.998	0.000
K85.1 Biliary acute pancreatitis	0.002	0.998	0.000
S00.7 Multiple superficial injuries of head	0.002	0.998	0.000
S00.4 Superficial injury of ear	0.002	0.998	0.000
S27.2 Traumatic heamopneumothorax	0.002	0.998	0.000
S39.8 Other specified injuries of abdomen, lower back and pelvis	0.002	0.998	0.000
S22.40 Multiple fractures of ribs (closed)	0.002	0.998	0.000
S02.3 Fracture of orbital floor	0.002	0.998	0.000
S39.9 Unspecified injury of abdomen, lower back and pelvis	0.002	0.998	0.000
S13 Dislocation, sprain and strain of joints and ligaments at neck level	0.002	0.998	0.000
S06.31 Focal brain injury (with open intracranial wound)	0.002	0.998	0.000
S00.3 Superficial injury of nose	0.002	0.998	0.000
S51.9 Open wound of forearm, part unspecified	0.002	0.998	0.000
S56.4 Injury of extensor muscle and tendon of other finger(s) at forearm level	0.002	0.998	0.000
D69 Purpura and other haemorrhagic conditions	0.002	0.998	0.000
S83.7 Injury to multiple structures of knee	0.002	0.998	0.000
S83.4 Sprain and strain involving (fibular)(tibial) collateral ligamnent of knee	0.002	0.998	0.000
S83.3 Tear of articular cartilage of knee, current	0.002	0.998	0.000
S83.1 Dislocation of knee	0.002	0.998	0.000
S83.0 Dislocation of patella	0.002	0.998	0.000
T81.2 Accidental puncture and laceration during a procedure, not elsewhere classified	0.000	0.998	0.002
O70.0 First degree perineal laceration during delivery	0.000	0.998	0.002
S40.0 Contusion of shoulder and upper arm	0.002	0.998	0.000
S56.1 Injury of flexor muscle and tendon of other finger(s) at forearm level	0.002	0.998	0.000
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system	0.002	0.998	0.000
D74 Methaemoglobinaemia	0.002	0.998	0.000
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere	0.002	0.998	0.000
D71 Functional disorders of polymorphonuclear neutrophils	0.002	0.998	0.000
S09 Other and unspecified injuries of head	0.002	0.998	0.000
S28 Crushing injury of thorax and traumatic amputation of part of thorax	0.002	0.998	0.000
S26 Injury of heart	0.002	0.998	0.000
S25 Injury of blood vessels of thorax	0.002	0.998	0.000
S24 Injury of nerves and spinal cord at thorax level	0.002	0.998	0.000
S23 Dislocation, sprain and strain of joints and ligaments of thorax	0.002	0.998	0.000
S21 Open wound of thorax	0.002	0.998	0.000
S06.30 Focal brain injury (without open intracranial wound)	0.002	0.998	0.000
D63.8 Anaemia in other chronic diseases classified elsewhere	0.002	0.998	0.000
S02.7 Multiple fractures involving skull and facial bones	0.002	0.998	0.000
S72.1 Pertrochanteric fracture	0.002	0.998	0.000
T67.9 Effects of heat and light, unspecified	0.002	0.998	0.000
T67.8 Other effects of heat and light	0.002	0.998	0.000
T67.7 Heat oedema	0.002	0.998	0.000
T67.6 Heat fatigue, transient	0.002	0.998	0.000
T67.5 Heat exhaustion, unspecified	0.002	0.998	0.000
T67.4 Heat exhaustion due to salt depletion	0.002	0.998	0.000
T67.3 Heat exhaustion, anhydrotic	0.002	0.998	0.000
T67.2 Heat cramp	0.002	0.998	0.000
T67.1 Heat syncope	0.002	0.998	0.000
T67.0 Heatstroke and sunstroke	0.002	0.998	0.000
T69.9 Effect of reduced temperature, unspecified	0.002	0.998	0.000
T69.8 Other specified effects of reduced temperature	0.002	0.998	0.000
T69.1 Chilblains	0.002	0.998	0.000
T69.0 Immersion hand and foot	0.002	0.998	0.000
T70.9 Effect of air pressure and water pressure, unspecified	0.002	0.998	0.000
T70.8 Other effects of air pressure and water pressure	0.002	0.998	0.000
T70.4 Effects of high-pressure fluids	0.002	0.998	0.000
T70.3 Caisson disease [decompression sickness]	0.002	0.998	0.000
T70.2 Other and unspecified effects of high altitude	0.002	0.998	0.000
T70.1 Sinus barotrauma	0.002	0.998	0.000
T70.0 Otitic barotrauma	0.002	0.998	0.000
T73.9 Effect of deprivation, unspecified	0.002	0.998	0.000
T73.8 Other effects of deprivation	0.002	0.998	0.000
T73.3 Exhaustion due to excessive exertion	0.002	0.998	0.000
T73.2 Exhaustion due to exposure	0.002	0.998	0.000
T73.1 Effects of thirst	0.002	0.998	0.000
T73.0 Effects of hunger	0.002	0.998	0.000
T74.9 Maltreatment syndrome, unspecified	0.002	0.998	0.000
T74.8 Other maltreatment syndromes	0.002	0.998	0.000
T74.3 Psychological abuse	0.002	0.998	0.000
T74.2 Sexual abuse	0.002	0.998	0.000
T74.1 Physical abuse	0.002	0.998	0.000
T74.0 Neglect or abandonment	0.002	0.998	0.000
T75.8 Other specified effects of external causes	0.002	0.998	0.000
T75.4 Effects of electric current	0.002	0.998	0.000
T75.3 Motion sickness	0.002	0.998	0.000
T75.2 Effects of vibration	0.002	0.998	0.000
T75.1 Drowning and nonfatal submersion	0.002	0.998	0.000
T75.0 Effects of lightning	0.002	0.998	0.000
S59 Other and unspecified injuries of forearm	0.002	0.998	0.000
S58 Traumatic amputation of forearm	0.002	0.998	0.000
S57 Crushing injury of forearm	0.002	0.998	0.000
S55 Injury of blood vessels at forearm level	0.002	0.998	0.000
S54 Injury of nerves at forearm level	0.002	0.998	0.000
S53 Dislocation, sprain and strain of joints and ligaments of elbow	0.002	0.998	0.000
T79 Certain early complications of trauma, not elsewhere classified	0.002	0.998	0.000
S06.61 Traumatic subarachnoid haemorrhage (with open intracranial wound)	0.002	0.998	0.000
K86.1 Other chronic pancreatitis	0.002	0.998	0.000
T39.1 4-Aminophenol derivatives	0.000	0.998	0.002
D75 Other diseases of blood and blood-forming organs	0.002	0.998	0.000
S17 Crushing injury of neck	0.002	0.998	0.000
S15 Injury of blood vessels at neck level	0.002	0.998	0.000
S14 Injury of nerves and spinal cord at neck level	0.002	0.998	0.000
S11 Open wound of neck	0.002	0.998	0.000
S18 Traumatic amputation at neck level	0.002	0.998	0.000
S16 Injury of muscle and tendon at neck level	0.002	0.998	0.000
S27.20 Traumatic haemopneumothorax (without open wound into thoracic cavity)	0.002	0.998	0.000
D81.9 Combined immunodeficiency, unspecified	0.002	0.998	0.000
D81.8 Other combined immunodeficiencies	0.002	0.998	0.000
D81.7 Major histocompatibility complex class II deficiency	0.002	0.998	0.000
D81.6 Major histocompatibility complex class I deficiency	0.002	0.998	0.000
D81.5 Purine nucleoside phosphorylase [PNP] deficiency	0.002	0.998	0.000
D81.4 Nezelof's syndrome	0.002	0.998	0.000
D81.3 Adenosine deaminase [ADA] deficiency	0.002	0.998	0.000
D81.2 Severe combined immunodeficiency [SCID] with low or normal B-cell numbers	0.002	0.998	0.000
D81.1 Severe combined immunodeficiency [SCID] with low T- and B-cell numbers	0.002	0.998	0.000
D81.0 Severe combined immunodeficiency [SCID] with reticular dysgenesis	0.002	0.998	0.000
D82.9 Immunodeficiency associated with major defect, unspecified	0.002	0.998	0.000
D82.8 Immunodeficiency associated with other specified major defects	0.002	0.998	0.000
D82.4 Hyperimmunoglobulin E [IgE] syndrome	0.002	0.998	0.000
D82.3 Immunodeficiency following hereditary defective response to Epstein-Barr virus	0.002	0.998	0.000
D82.2 Immunodeficiency with short-limbed stature	0.002	0.998	0.000
D82.1 Di George's syndrome	0.002	0.998	0.000
D82.0 Wiskott-Aldrich syndrome	0.002	0.998	0.000
D83.9 Common variable immunodeficiency, unspecified	0.002	0.998	0.000
D83.8 Other common variable immunodeficiencies	0.002	0.998	0.000
D83.2 Common variable immunodeficiency with autoantibodies to B- or T-cells	0.002	0.998	0.000
D83.1 Common variable immunodeficiency with predominant immunoregulatory T-cell disorders	0.002	0.998	0.000
D83.0 Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function	0.002	0.998	0.000
D84.9 Immunodeficiency, unspecified	0.002	0.998	0.000
D84.8 Other specified immunodeficiencies	0.002	0.998	0.000
D84.1 Defects in the complement system	0.002	0.998	0.000
D84.0 Lymphocyte function antigen-1 [LFA-1] defect	0.002	0.998	0.000
S00.2 Other superficial injuries of eyelid and periocular area	0.002	0.998	0.000
S02.1 Fracture of base of skull	0.002	0.998	0.000
S52.6 Fracture of lower end of both ulna and radius	0.002	0.998	0.000
S72.2 Subtrochanteric fracture	0.002	0.998	0.000
T13 Other injuries of lower limb, level unspecified	0.002	0.998	0.000
T09 Other injuries of spine and trunk, level unspecified	0.002	0.998	0.000
T12.X1 Fracture of lower limb, level unspecified (open)	0.002	0.998	0.000
T12.X0 Fracture of lower limb, level unspecified (closed)	0.002	0.998	0.000
T12 Fracture of lower limb, level unspecified	0.002	0.998	0.000
T10.X1 Fracture of upper limb, level unspecified (open)	0.002	0.998	0.000
T10.X0 Fracture of upper limb, level unspecified (closed)	0.002	0.998	0.000
T10 Fracture of upper limb, level unspecified	0.002	0.998	0.000
T08.X1 Fracture of spine, level unspecified (open)	0.002	0.998	0.000
T08.X0 Fracture of spine, level unspecified (closed)	0.002	0.998	0.000
T08 Fracture of spine, level unspecified	0.002	0.998	0.000
T65 Toxic effect of other and unspecified substances	0.002	0.998	0.000
T62 Toxic effect of other noxious substances eaten as food	0.002	0.998	0.000
T61 Toxic effect of noxious substances eaten as seafood	0.002	0.998	0.000
T60 Toxic effect of pesticides	0.002	0.998	0.000
T57 Toxic effect of other inorganic substances	0.002	0.998	0.000
T56 Toxic effect of metals	0.002	0.998	0.000
T54 Toxic effect of corrosive substances	0.002	0.998	0.000
T53 Toxic effect of halogen derivatives of aliphatic and aromatic hydrocarbone	0.002	0.998	0.000
T52 Toxic effect of organic solvents	0.002	0.998	0.000
T64 Toxic effect of aflatoxin and other mycotoxin food contaminants	0.002	0.998	0.000
T55 Toxic effect of soaps and detergents	0.002	0.998	0.000
S56.2 Injury of other flexor muscle and tendon at forearm level	0.002	0.998	0.000
S56.7 Injury of multiple muscles and tendons at forearm level	0.002	0.998	0.000
S56.5 Injury of other extensor muscle and tendon at forearm level	0.002	0.998	0.000
S56.3 Injury of extensor or abductor muscles and tendons of thumb at forearm level	0.002	0.998	0.000
S56.0 Injury of flexor muscle and tendon of thumb at forearm level	0.002	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations