TreeWAS – Variant ID: rs4899329

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
M19.91 Arthrosis, unspecified (Shoulder region)	0.000	0.875	0.125
I35.9 Aortic valve disorder, unspecified	0.084	0.916	0.000
I35 Nonrheumatic aortic valve disorders	0.081	0.919	0.000
I35.8 Other aortic valve disorders	0.077	0.923	0.000
I35.0 Aortic (valve) stenosis	0.070	0.930	0.000
I35.2 Aortic (valve) stenosis with insufficiency	0.069	0.931	0.000
I35.1 Aortic (valve) insufficiency	0.065	0.935	0.000
L72.8 Other follicular cysts of skin and subcutaneous tissue	0.000	0.963	0.037
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)	0.024	0.976	0.000
F05.9 Delirium, unspecified	0.024	0.976	0.000
M05.9 Seropositive rheumatoid arthritis, unspecified	0.021	0.979	0.000
F05 Delirium, not induced by alcohol and other psychoactive substances	0.019	0.981	0.000
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)	0.018	0.982	0.000
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.018	0.982	0.000
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)	0.017	0.983	0.000
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)	0.017	0.983	0.000
F05.1 Delirium superimposed on dementia	0.016	0.983	0.000
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)	0.016	0.984	0.000
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)	0.016	0.984	0.000
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)	0.016	0.984	0.000
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)	0.015	0.985	0.000
F05.0 Delirium not superimposed on dementia, so described	0.015	0.985	0.000
F00-F09 Organic, including symptomatic, mental disorders	0.015	0.985	0.000
F02 Dementia in other diseases classified elsewhere	0.014	0.986	0.000
F01 Vascular dementia	0.014	0.986	0.000
F02.0 Dementia in Pick's disease	0.013	0.987	0.000
F01.9 Vascular dementia, unspecified	0.013	0.987	0.000
F09 Unspecified organic or symptomatic mental disorder	0.012	0.988	0.000
F02.3 Dementia in Parkinson's disease	0.012	0.988	0.000
M05 Seropositive rheumatoid arthritis	0.012	0.988	0.000
F02.8 Dementia in other specified diseases classified elsewhere	0.011	0.989	0.000
F07 Personality and behavioural disorders due to brain disease, damage and dysfunction	0.011	0.989	0.000
F06 Other mental disorders due to brain damage and dysfunction and to physical disease	0.011	0.989	0.000
F04 Organic amnesic syndrome, not induced by alcohol and other psychoactive substances	0.011	0.989	0.000
F01.1 Multi-infarct dementia	0.011	0.989	0.000
O99.6 Diseases of the digestive system complicating pregnancy, childbirth and the puerperium	0.000	0.989	0.011
F02.4 Dementia in human immunodeficiency virus [HIV] disease	0.010	0.990	0.000
F02.2 Dementia in Huntington's disease	0.010	0.990	0.000
F02.1 Dementia in Creutzfeldt-Jakob disease	0.010	0.990	0.000
C79.8 Secondary malignant neoplasm of other specified sites	0.010	0.990	0.000
F01.8 Other vascular dementia	0.010	0.990	0.000
F01.3 Mixed cortical and subcortical vascular dementia	0.010	0.990	0.000
F01.2 Subcortical vascular dementia	0.010	0.990	0.000
F01.0 Vascular dementia of acute onset	0.010	0.990	0.000
M05.0 Felty's syndrome	0.010	0.990	0.000
F06.8 Other specified mental disorders due to brain damage and dysfunction and to physical disease	0.009	0.991	0.000
M05.8 Other seropositive rheumatoid arthritis	0.009	0.991	0.000
M05.2 Rheumatoid vasculitis	0.009	0.991	0.000
M05.1 Rheumatoid lung disease	0.009	0.991	0.000
F07.0 Organic personality disorder	0.009	0.991	0.000
M05.3 Rheumatoid arthritis with involvement of other organs and systems	0.009	0.991	0.000
F06.9 Unspecified mental disorder due to brain damage and dysfunction and to physical disease	0.009	0.991	0.000
F07.9 Unspecified organic personality and behavioural disorder due to brain disease, damage and dysfunction	0.008	0.991	0.000
M05.09 Felty's syndrome (Site unspecified)	0.008	0.992	0.000
F07.8 Other organic personality and behavioural disorders due to brain disease, damage and dysfunction	0.008	0.992	0.000
F07.1 Postencephalitic syndrome	0.008	0.992	0.000
F05.8 Other delirium	0.008	0.992	0.000
F06.6 Organic emotionally labile [asthenic] disorder	0.008	0.992	0.000
F06.5 Organic dissociative disorder	0.008	0.992	0.000
F06.4 Organic anxiety disorder	0.008	0.992	0.000
F06.3 Organic mood [affective] disorders	0.008	0.992	0.000
F06.1 Organic catatonic disorder	0.008	0.992	0.000
F06.0 Organic hallucinosis	0.008	0.992	0.000
F07.2 Postconcussional syndrome	0.008	0.992	0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.000	0.992	0.008
F06.2 Organic delusional [schizophrenia-like] disorder	0.007	0.992	0.000
O99.3 Mental disorders and diseases of the nervous system complicating pregnancy, childbirth and the puerperium	0.000	0.992	0.008
L29.8 Other pruritus	0.000	0.993	0.007
M05.08 Felty's syndrome (Other)	0.007	0.993	0.000
M05.07 Felty's syndrome (Ankle and foot)	0.007	0.993	0.000
M05.06 Felty's syndrome (Lower leg)	0.007	0.993	0.000
M05.05 Felty's syndrome (Pelvic region and thigh)	0.007	0.993	0.000
M05.04 Felty's syndrome (Hand)	0.007	0.993	0.000
M05.03 Felty's syndrome (Forearm)	0.007	0.993	0.000
M05.02 Felty's syndrome (Upper arm)	0.007	0.993	0.000
M05.01 Felty's syndrome (Shoulder region)	0.007	0.993	0.000
M05.00 Felty's syndrome (Multiple sites)	0.007	0.993	0.000
D06.9 Cervix, unspecified	0.000	0.993	0.007
O99.7 Diseases of the skin and subcutaneous tissue complicating pregnancy, childbirth and the puerperium	0.000	0.993	0.007
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)	0.007	0.993	0.000
F00 Dementia in Alzheimer's disease	0.007	0.993	0.000
O99.5 Diseases of the respiratory system complicating pregnancy, childbirth and the puerperium	0.000	0.993	0.007
M05.89 Other seropositive rheumatoid arthritis (Site unspecified)	0.007	0.993	0.000
L29.9 Pruritus, unspecified	0.000	0.993	0.007
Z29.2 Other prophylactic chemotherapy	0.000	0.993	0.007
M05.80 Other seropositive rheumatoid arthritis (Multiple sites)	0.007	0.993	0.000
N95.2 Postmenopausal atrophic vaginitis	0.000	0.993	0.007
M05.88 Other seropositive rheumatoid arthritis (Other)	0.007	0.993	0.000
M05.87 Other seropositive rheumatoid arthritis (Ankle and foot)	0.007	0.993	0.000
M05.86 Other seropositive rheumatoid arthritis (Lower leg)	0.007	0.993	0.000
M05.85 Other seropositive rheumatoid arthritis (Pelvic region and thigh)	0.007	0.993	0.000
M05.84 Other seropositive rheumatoid arthritis (Hand)	0.007	0.993	0.000
M05.83 Other seropositive rheumatoid arthritis (Forearm)	0.007	0.993	0.000
M05.82 Other seropositive rheumatoid arthritis (Upper arm)	0.007	0.993	0.000
M05.81 Other seropositive rheumatoid arthritis (Shoulder region)	0.007	0.993	0.000
M05.20 Rheumatoid vasculitis (Multiple sites)	0.007	0.993	0.000
M05.19 Rheumatoid lung disease (Site unspecified)	0.007	0.993	0.000
M05.29 Rheumatoid vasculitis (Site unspecified)	0.007	0.993	0.000
L29 Pruritus	0.000	0.993	0.007
M05.28 Rheumatoid vasculitis (Other)	0.006	0.993	0.000
M05.27 Rheumatoid vasculitis (Ankle and foot)	0.006	0.993	0.000
M05.26 Rheumatoid vasculitis (Lower leg)	0.006	0.993	0.000
M05.25 Rheumatoid vasculitis (Pelvic region and thigh)	0.006	0.993	0.000
M05.24 Rheumatoid vasculitis (Hand)	0.006	0.993	0.000
M05.23 Rheumatoid vasculitis (Forearm)	0.006	0.993	0.000
M05.22 Rheumatoid vasculitis (Upper arm)	0.006	0.993	0.000
M05.21 Rheumatoid vasculitis (Shoulder region)	0.006	0.993	0.000
L29.0 Pruritus ani	0.000	0.993	0.007
M05.18 Rheumatoid lung disease (Other)	0.006	0.993	0.000
M05.17 Rheumatoid lung disease (Ankle and foot)	0.006	0.993	0.000
M05.16 Rheumatoid lung disease (Lower leg)	0.006	0.993	0.000
M05.15 Rheumatoid lung disease (Pelvic region and thigh)	0.006	0.993	0.000
M05.14 Rheumatoid lung disease (Hand)	0.006	0.993	0.000
M05.13 Rheumatoid lung disease (Forearm)	0.006	0.993	0.000
M05.12 Rheumatoid lung disease (Upper arm)	0.006	0.993	0.000
M05.11 Rheumatoid lung disease (Shoulder region)	0.006	0.993	0.000
M05.10 Rheumatoid lung disease (Multiple sites)	0.006	0.993	0.000
M05.39 Rheumatoid arthritis with involvement of other organs and systems (Site unspecified)	0.006	0.993	0.000
M05.38 Rheumatoid arthritis with involvement of other organs and systems (Other)	0.006	0.993	0.000
M05.37 Rheumatoid arthritis with involvement of other organs and systems (Ankle and foot)	0.006	0.993	0.000
M05.36 Rheumatoid arthritis with involvement of other organs and systems (Lower leg)	0.006	0.993	0.000
M05.35 Rheumatoid arthritis with involvement of other organs and systems (Pelvic region and thigh)	0.006	0.993	0.000
M05.34 Rheumatoid arthritis with involvement of other organs and systems (Hand)	0.006	0.993	0.000
M05.33 Rheumatoid arthritis with involvement of other organs and systems (Forearm)	0.006	0.993	0.000
M05.32 Rheumatoid arthritis with involvement of other organs and systems (Upper arm)	0.006	0.993	0.000
M05.31 Rheumatoid arthritis with involvement of other organs and systems (Shoulder region)	0.006	0.993	0.000
M05.30 Rheumatoid arthritis with involvement of other organs and systems (Multiple sites)	0.006	0.993	0.000
H18.4 Corneal degeneration	0.006	0.994	0.000
K11.2 Sialoadenitis	0.006	0.994	0.000
F03 Unspecified dementia	0.006	0.994	0.000
F06.7 Mild cognitive disorder	0.006	0.994	0.000
H18 Other disorders of cornea	0.006	0.994	0.000
O99.4 Diseases of the circulatory system complicating pregnancy, childbirth and the puerperium	0.000	0.994	0.006
H18.5 Hereditary corneal dystrophies	0.006	0.994	0.000
C79.7 Secondary malignant neoplasm of adrenal gland	0.006	0.994	0.000
S51.9 Open wound of forearm, part unspecified	0.000	0.994	0.006
H18.8 Other specified disorders of cornea	0.006	0.994	0.000
E13.9 Without complications	0.005	0.995	0.000
L29.3 Anogenital pruritus, unspecified	0.000	0.995	0.005
O99.2 Endocrine, nutritional and metabolic diseases complicating pregnancy, childbirth and the puerperium	0.000	0.995	0.005
F00.0 Dementia in Alzheimer's disease with early onset	0.005	0.995	0.000
C79.6 Secondary malignant neoplasm of ovary	0.005	0.995	0.000
L29.1 Pruritus scroti	0.000	0.995	0.005
C79 Secondary malignant neoplasm of other sites	0.005	0.995	0.000
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system	0.005	0.995	0.000
H18.3 Changes in corneal membranes	0.005	0.995	0.000
H18.9 Disorder of cornea, unspecified	0.005	0.995	0.000
H18.6 Keratoconus	0.005	0.995	0.000
F00.1 Dementia in Alzheimer's disease with late onset	0.004	0.995	0.000
H18.7 Other corneal deformities	0.004	0.995	0.000
H18.1 Bullous keratopathy	0.004	0.996	0.000
F00.9 Dementia in Alzheimer's disease, unspecified	0.004	0.996	0.000
F00.2 Dementia in Alzheimer's disease, atypical or mixed type	0.004	0.996	0.000
H18.0 Corneal pigmentations and deposits	0.004	0.996	0.000
O30.0 Twin pregnancy	0.000	0.996	0.004
T43.2 Other and unspecified antidepressants	0.000	0.996	0.004
H18.2 Other corneal oedema	0.004	0.996	0.000
O99.1 Other diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism complicating pregnancy, childbirth and the puerperium	0.000	0.996	0.004
C79.9 Secondary malignant neoplasm, unspecified site	0.004	0.996	0.000
O99.8 Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium	0.000	0.996	0.004
C79.2 Secondary malignant neoplasm of skin	0.004	0.996	0.000
Z52.4 Kidney donor	0.000	0.996	0.004
O94-O99 Other obstetric conditions, not elsewhere classified	0.000	0.997	0.003
S64.2 Injury of radial nerve at wrist and hand level	0.003	0.997	0.000
O99.0 Anaemia complicating pregnancy, childbirth and the puerperium	0.000	0.997	0.003
L30.8 Other specified dermatitis	0.000	0.997	0.003
M23.35 Other meniscus derangements (Posterior horn of lateral meniscus)	0.003	0.997	0.000
D46.9 Myelodysplastic syndrome, unspecified	0.003	0.997	0.000
H19.1 Herpesviral keratitis and keratoconjunctivitis	0.003	0.997	0.000
M19.98 Arthrosis, unspecified (Other)	0.000	0.997	0.003
H19 Disorders of sclera and cornea in diseases classified elsewhere	0.003	0.997	0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.003	0.997	0.000
H15.8 Other disorders of sclera	0.003	0.997	0.000
H15 Disorders of sclera	0.003	0.997	0.000
D06 Carcinoma in situ of cervix uteri	0.000	0.997	0.003
Z80.9 Family history of malignant neoplasm, unspecified	0.000	0.997	0.003
M19.9 Arthrosis, unspecified	0.000	0.997	0.003
J32.0 Chronic maxillary sinusitis	0.000	0.997	0.003
L29.2 Pruritus vulvae	0.002	0.997	0.001
O98 Maternal infectious and parasitic diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.000	0.997	0.003
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs	0.003	0.997	0.000
O97 Death from sequelae of direct obstetric causes	0.000	0.997	0.003
O96 Death from any obstetric cause occurring more than 42 days but less than one year after delivery	0.000	0.997	0.003
O95 Obstetric death of unspecified cause	0.000	0.997	0.003
O94 Sequelae of complication of pregnancy, childbirth and the puerperium	0.000	0.997	0.003
R70.0 Elevated erythrocyte sedimentation rate	0.003	0.997	0.000
T43.4 Butyrophenone and thioxanthene neuroleptics	0.000	0.997	0.003
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.000	0.997	0.003
H19.2 Keratitis and keratoconjunctivitis in other infectious and parasitic diseases classified elsewhere	0.003	0.997	0.000
H15.1 Episcleritis	0.003	0.997	0.000
H20 Iridocyclitis	0.003	0.997	0.000
H19.3 Keratitis and keratoconjunctivitis in other diseases classified elsewhere	0.003	0.997	0.000
M19.95 Arthrosis, unspecified (Pelvic region and thigh)	0.000	0.997	0.003
H19.8 Other disorders of sclera and cornea in diseases classified elsewhere	0.002	0.997	0.000
H19.0 Scleritis and episcleritis in diseases classified elsewhere	0.002	0.997	0.000
H20.9 Iridocyclitis, unspecified	0.003	0.997	0.000
T43.6 Psychostimulants with abuse potential	0.000	0.997	0.002
L30.4 Erythema intertrigo	0.000	0.997	0.002
E13 Other specified diabetes mellitus	0.002	0.997	0.000
H15.0 Scleritis	0.002	0.997	0.000
D06.0 Endocervix	0.000	0.998	0.002
D06.7 Other parts of cervix	0.000	0.998	0.002
L30 Other dermatitis	0.000	0.998	0.002
S51 Open wound of forearm	0.000	0.998	0.002
O98.3 Other infections with a predominantly sexual mode of transmission complicating pregnancy, childbirth and the puerperium	0.000	0.998	0.002
C79.0 Secondary malignant neoplasm of kidney and renal pelvis	0.002	0.998	0.000
H22 Disorders of iris and ciliary body in diseases classified elsewhere	0.002	0.998	0.000
H20.8 Other iridocyclitis	0.002	0.998	0.000
D06.1 Exocervix	0.000	0.998	0.002
Z52 Donors of organs and tissues	0.000	0.998	0.002
L20-L30 Dermatitis and eczema	0.000	0.998	0.002
H15.9 Disorder of sclera, unspecified	0.002	0.998	0.000
O98.9 Unspecified maternal infectious or parasitic disease complicating pregnancy, childbirth and the puerperium	0.000	0.998	0.002
O98.7 Human immunodeficiency [HIV] disease complicating pregnancy, childbirth and the puerperium	0.000	0.998	0.002
O98.6 Protozoal diseases complicating pregnancy, childbirth and the puerperium	0.000	0.998	0.002
O98.5 Other viral diseases complicating pregnancy, childbirth and the puerperium	0.000	0.998	0.002
O98.4 Viral hepatitis complicating pregnancy, childbirth and the puerperium	0.000	0.998	0.002
O98.2 Gonorrhoea complicating pregnancy, childbirth and the puerperium	0.000	0.998	0.002
O98.1 Syphilis complicating pregnancy, childbirth and the puerperium	0.000	0.998	0.002
O98.0 Tuberculosis complicating pregnancy, childbirth and the puerperium	0.000	0.998	0.002
C79.3 Secondary malignant neoplasm of brain and cerebral meninges	0.002	0.998	0.000
N76.0 Acute vaginitis	0.000	0.998	0.002
O96.9 Death from unspecified obstetric cause	0.000	0.998	0.002
O96.1 Death from indirect obstetric cause	0.000	0.998	0.002
O96.0 Death from direct obstetric cause	0.000	0.998	0.002
O97.9 Death from sequelae of obstetric cause, unspecified	0.000	0.998	0.002
O97.1 Death from sequelae of indirect obstetric cause	0.000	0.998	0.002
O97.0 Death from sequelae of direct obstetric cause	0.000	0.998	0.002
T43.9 Psychotropic drug, unspecified	0.000	0.998	0.002
I78.1 Naevus, nonneoplastic	0.002	0.998	0.000
T43.8 Other psychotropic drugs, not elsewhere classified	0.000	0.998	0.002
T43.0 Tricyclic and tetracyclic antidepressants	0.000	0.998	0.002
M19.93 Arthrosis, unspecified (Forearm)	0.000	0.998	0.002
C82.9 Follicular non-Hodgkin's lymphoma, unspecified	0.002	0.998	0.000
E13.3 With ophthalmic complications	0.002	0.998	0.000
H20.2 Lens-induced iridocyclitis	0.002	0.998	0.000
S12.00 Fracture of first cervical vertebra (closed)	0.000	0.998	0.002
O98.8 Other maternal infectious and parasitic diseases complicating pregnancy, childbirth and the puerperium	0.000	0.998	0.002
Z52.0 Blood donor	0.000	0.998	0.002
S51.0 Open wound of elbow	0.000	0.998	0.002
Z52.3 Bone marrow donor	0.000	0.998	0.002
E13.8 With unspecified complications	0.002	0.998	0.000
E13.7 With multiple complications	0.002	0.998	0.000
E13.6 With other specified complications	0.002	0.998	0.000
E13.5 With peripheral circulatory complications	0.002	0.998	0.000
E13.4 With neurological complications	0.002	0.998	0.000
E13.2 With renal complications	0.002	0.998	0.000
E13.1 With ketoacidosis	0.002	0.998	0.000
E13.0 With coma	0.002	0.998	0.000
Z52.8 Donor of other organs and tissues	0.000	0.998	0.002
H17 Corneal scars and opacities	0.002	0.998	0.000
M19.96 Arthrosis, unspecified-Lower leg	0.000	0.998	0.002
S51.7 Multiple open wounds of forearm	0.000	0.998	0.002
H21 Other disorders of iris and ciliary body	0.002	0.998	0.000
L30.5 Pityriasis alba	0.000	0.998	0.002
L30.2 Cutaneous autosensitisation	0.000	0.998	0.002
H22.8 Other disorders of iris and ciliary body in diseases classified elsewhere	0.002	0.998	0.000
H22.0 Iridocyclitis in infectious and parasitic diseases classified elsewhere	0.002	0.998	0.000
L21 Seborrhoeic dermatitis	0.000	0.998	0.002
M50.2 Other cervical disk displacement	0.000	0.998	0.002
S12.70 Multiple fractures of cervical spine (closed)	0.000	0.998	0.002
C14.0 Pharynx, unspecified	0.000	0.998	0.002
T43.3 Phenothiazine antipsychotics and neuroleptics	0.000	0.998	0.002
Z52.9 Donor of unspecified organ or tissue	0.000	0.998	0.002
Z52.7 Heart donor	0.000	0.998	0.002
Z52.6 Liver donor	0.000	0.998	0.002
Z52.5 Cornea donor	0.000	0.998	0.002
Z52.1 Skin donor	0.000	0.998	0.002
O30 Multiple gestation	0.000	0.998	0.002
L24 Irritant contact dermatitis	0.000	0.998	0.002
L22 Diaper [napkin] dermatitis	0.000	0.998	0.002
S62.30 Fracture of other metacarpal bone (closed)	0.000	0.998	0.002
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.000	0.998	0.002
H20.1 Chronic iridocyclitis	0.002	0.998	0.000
L30.3 Infective dermatitis	0.000	0.998	0.002
Z52.2 Bone donor	0.000	0.998	0.002
B80 Enterobiasis	0.000	0.998	0.002
L20 Atopic dermatitis	0.000	0.998	0.002
H21.4 Pupillary membranes	0.002	0.998	0.000
H22.1 Iridocyclitis in other diseases classified elsewhere	0.002	0.998	0.000
L30.0 Nummular dermatitis	0.000	0.998	0.002
L25 Unspecified contact dermatitis	0.000	0.998	0.002
L26 Exfoliative dermatitis	0.000	0.998	0.002
M24.86 Other specific joint derangements, not elsewhere classified (Lower leg)	0.000	0.998	0.002
S12.0 Fracture of first cervical vertebra	0.000	0.998	0.002
T43.5 Other and unspecified antipsychotics and neuroleptics	0.000	0.998	0.002
L23 Allergic contact dermatitis	0.000	0.998	0.002
L30.1 Dyshidrosis [pompholyx]	0.000	0.998	0.002
H17.1 Other central corneal opacity	0.002	0.998	0.000
H17.0 Adherent leukoma	0.002	0.998	0.000
H21.2 Degeneration of iris and ciliary body	0.002	0.998	0.000
L21.9 Seborrhoeic dermatitis, unspecified	0.000	0.998	0.002
D46 Myelodysplastic syndromes	0.002	0.998	0.000
G58.9 Mononeuropathy, unspecified	0.002	0.998	0.000
H21.3 Cyst of iris, ciliary body and anterior chamber	0.002	0.998	0.000
T18.1 Foreign body in oesophagus	0.000	0.998	0.002
N92.3 Ovulation bleeding	0.002	0.998	0.000
L21.8 Other seborrhoeic dermatitis	0.000	0.998	0.002
L21.1 Seborrhoeic infantile dermatitis	0.000	0.998	0.002
L21.0 Seborrhoea capitis	0.000	0.998	0.002
S12.7 Multiple fractures of cervical spine	0.000	0.998	0.002
H16 Keratitis	0.002	0.998	0.000
D46.2 Refractory anaemia with excess of blasts	0.002	0.998	0.000
H21.8 Other specified disorders of iris and ciliary body	0.002	0.998	0.000
O30.1 Triplet pregnancy	0.000	0.998	0.002
C82.1 Mixed small cleaved and large cell, follicular	0.002	0.998	0.000
H17.8 Other corneal scars and opacities	0.001	0.998	0.000
M89.87 Other specified disorders of bone (Ankle and foot)	0.000	0.998	0.002
H16.2 Keratoconjunctivitis	0.002	0.998	0.000
O30.9 Multiple gestation, unspecified	0.000	0.998	0.002
O30.8 Other multiple gestation	0.000	0.998	0.002
O30.2 Quadruplet pregnancy	0.000	0.998	0.002
E16.2 Hypoglycaemia, unspecified	0.002	0.998	0.000
H20.0 Acute and subacute iridocyclitis	0.001	0.998	0.000
L24.9 Irritant contact dermatitis, unspecified cause	0.000	0.998	0.001
L24.8 Irritant contact dermatitis due to other agents	0.000	0.998	0.001
L24.7 Irritant contact dermatitis due to plants, except food	0.000	0.998	0.001
L24.6 Irritant contact dermatitis due to food in contact with the skin	0.000	0.998	0.001
L24.5 Irritant contact dermatitis due to other chemical products	0.000	0.998	0.001
L24.4 Irritant contact dermatitis due to drugs in contact with the skin	0.000	0.998	0.001
L24.3 Irritant contact dermatitis due to cosmetics	0.000	0.998	0.001
L24.2 Irritant contact dermatitis due to solvents	0.000	0.998	0.001
L24.1 Irritant contact dermatitis due to oils and greases	0.000	0.998	0.001
L24.0 Irritant contact dermatitis due to detergents	0.000	0.998	0.001
F43.0 Acute stress reaction	0.000	0.998	0.002
H21.9 Disorder of iris and ciliary body, unspecified	0.001	0.998	0.000
L27 Dermatitis due to substances taken internally	0.000	0.998	0.002
D46.5 Refractory anaemia with multi-lineage dysplasia	0.002	0.998	0.000
H21.5 Other adhesions and disruptions of iris and ciliary body	0.002	0.998	0.000
L20.0 Besnier's prurigo	0.000	0.998	0.001
L56.8 Other specified acute skin changes due to ultraviolet radiation	0.000	0.998	0.002
L20.8 Other atopic dermatitis	0.000	0.998	0.001
L23.3 Allergic contact dermatitis due to drugs in contact with the skin	0.000	0.998	0.001
L25.8 Unspecified contact dermatitis due to other agents	0.000	0.998	0.001
L25.5 Unspecified contact dermatitis due to plants, except food	0.000	0.998	0.001
L25.4 Unspecified contact dermatitis due to food in contact with the skin	0.000	0.998	0.001
L25.3 Unspecified contact dermatitis due to other chemical products	0.000	0.998	0.001
L25.2 Unspecified contact dermatitis due to dyes	0.000	0.998	0.001
L25.1 Unspecified contact dermatitis due to drugs in contact with the skin	0.000	0.998	0.001
L25.0 Unspecified contact dermatitis due to cosmetics	0.000	0.998	0.001
L72.9 Follicular cyst of skin and subcutaneous tissue, unspecified	0.002	0.998	0.000
R73.0 Abnormal glucose tolerance test	0.000	0.998	0.002
S12.01 Fracture of first cervical vertebra (open)	0.000	0.998	0.001
E29.1 Testicular hypofunction	0.000	0.998	0.002
L20.9 Atopic dermatitis, unspecified	0.000	0.998	0.001
L23.7 Allergic contact dermatitis due to plants, except food	0.000	0.998	0.001
L23.6 Allergic contact dermatitis due to food in contact with the skin	0.000	0.998	0.001
L23.4 Allergic contact dermatitis due to dyes	0.000	0.998	0.001
L23.2 Allergic contact dermatitis due to cosmetics	0.000	0.998	0.001
L23.1 Allergic contact dermatitis due to adhesives	0.000	0.998	0.001
L23.0 Allergic contact dermatitis due to metals	0.000	0.998	0.001
L23.9 Allergic contact dermatitis, unspecified cause	0.000	0.998	0.001
R57.0 Cardiogenic shock	0.002	0.998	0.000
M48.54 Collapsed vertebra, not elsewhere classified (Thoracic region)	0.000	0.998	0.002
D46.6 Myelodysplastic syndrome with isolated del(5q) chromosomal abnormality	0.001	0.998	0.000
D46.4 Refractory anaemia, unspecified	0.001	0.998	0.000
D46.3 Refractory anaemia with excess of blasts with transformation	0.001	0.998	0.000
D46.0 Refractory anaemia without sideroblasts, so stated	0.001	0.998	0.000
D46.1 Refractory anaemia with sideroblasts	0.001	0.998	0.000
L23.5 Allergic contact dermatitis due to other chemical products	0.000	0.998	0.001
O87.2 Haemorrhoids in the puerperium	0.001	0.998	0.000
S51.8 Open wound of other parts of forearm	0.000	0.998	0.001
H46 Optic neuritis	0.000	0.998	0.002
I70.00 Atherosclerosis of aorta (without gangrene)	0.001	0.998	0.000
S12.71 Multiple fractures of cervical spine (open)	0.000	0.998	0.001
B97.8 Other viral agents as the cause of diseases classified to other chapters	0.000	0.998	0.002
C82 Follicular [nodular] non-Hodgkin's lymphoma	0.002	0.998	0.000
S12 Fracture of neck	0.000	0.998	0.001
S92.20 Fracture of other tarsal bone(s) (closed)	0.000	0.998	0.001
A87.9 Viral meningitis, unspecified	0.001	0.998	0.000
M23.51 Chronic instability of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)	0.000	0.999	0.001
S82.60 Fracture of lateral malleolus (closed)	0.001	0.999	0.000
H21.1 Other vascular disorders of iris and ciliary body	0.001	0.999	0.000
D46.7 Other myelodysplastic syndromes	0.001	0.999	0.000
H16.3 Interstitial and deep keratitis	0.001	0.999	0.000
L25.9 Unspecified contact dermatitis, unspecified cause	0.000	0.999	0.001
S12.2 Fracture of other specified cervical vertebra	0.000	0.999	0.001
L27.9 Dermatitis due to unspecified substance taken internally	0.000	0.999	0.001
L27.8 Dermatitis due to other substances taken internally	0.000	0.999	0.001
L27.0 Generalised skin eruption due to drugs and medicaments	0.000	0.999	0.001
M49.54 Collapsed vertebra in diseases classified elsewhere (Thoracic region)	0.000	0.999	0.001
H16.4 Corneal neovascularisation	0.001	0.999	0.000
H21.0 Hyphaema	0.001	0.999	0.000
S12.20 Fracture of other specified cervical vertebra (closed)	0.000	0.999	0.001
L23.8 Allergic contact dermatitis due to other agents	0.000	0.999	0.001
C82.7 Other types of follicular non-Hodgkin's lymphoma	0.001	0.999	0.000
H17.9 Corneal scar and opacity, unspecified	0.001	0.999	0.000
W26.8 Other specified place	0.001	0.999	0.000
M89.86 Other specified disorders of bone (Lower leg)	0.000	0.999	0.001
S02.30 Fracture of orbital floor (closed)	0.001	0.999	0.000
C82.4 Follicular lymphoma grade IIIb	0.001	0.999	0.000
S12.9 Fracture of neck, part unspecified	0.000	0.999	0.001
X49.9 Unspecified place	0.001	0.999	0.000
C82.6 Cutaneous follicle centre lymphoma	0.001	0.999	0.000
C82.5 Diffuse follicle centre lymphoma	0.001	0.999	0.000
C82.3 Follicular lymphoma grade IIIa	0.001	0.999	0.000
S12.8 Fracture of other parts of neck	0.000	0.999	0.001
S01.8 Open wound of other parts of head	0.001	0.999	0.000
L28 Lichen simplex chronicus and prurigo	0.001	0.999	0.001
S12.21 Fracture of other specified cervical vertebra (open)	0.000	0.999	0.001
H16.9 Keratitis, unspecified	0.001	0.999	0.000
H16.1 Other superficial keratitis without conjunctivitis	0.001	0.999	0.000
L27.1 Localised skin eruption due to drugs and medicaments	0.000	0.999	0.001
F81.9 Developmental disorder of scholastic skills, unspecified	0.000	0.999	0.001
H40.1 Primary open-angle glaucoma	0.001	0.999	0.000
S12.1 Fracture of second cervical vertebra	0.000	0.999	0.001
C82.2 Large cell, follicular	0.001	0.999	0.000
H16.8 Other keratitis	0.001	0.999	0.000
S41.1 Open wound of upper arm	0.000	0.999	0.001
Z50.9 Care involving use of rehabilitation procedure, unspecified	0.000	0.999	0.001
Z71.3 Dietary counselling and surveillance	0.001	0.999	0.000
C82.0 Small cleaved cell, follicular	0.001	0.999	0.000
I70.10 Atherosclerosis of renal artery (without gangrene)	0.001	0.999	0.000
S12.91 Fracture of neck, part unspecified (open)	0.000	0.999	0.001
Z36.3 Antenatal screening for malformations using ultrasound and other physical methods	0.001	0.999	0.000
S12.81 Fracture of other parts of neck (open)	0.000	0.999	0.001
S12.80 Fracture of other parts of neck (closed)	0.000	0.999	0.001
S12.90 Fracture of neck, part unspecified (closed)	0.000	0.999	0.001
S82.01 Fracture of patella (open)	0.001	0.999	0.000
F40.2 Specific (isolated) phobias	0.001	0.999	0.000
M89.85 Other specified disorders of bone (Pelvic region and thigh)	0.000	0.999	0.001
S22.30 Fracture of rib (closed)	0.001	0.999	0.000
C91.1 Chronic lymphocytic leukaemia	0.000	0.999	0.001
Y65.8 Other specified misadventures during surgical and medical care	0.001	0.999	0.000
M19.13 Post-traumatic arthrosis of other joints (Forearm)	0.001	0.999	0.000
S06.40 Epidural haemorrhage (without open intracranial wound)	0.000	0.999	0.001
S12.11 Fracture of second cervical vertebra (open)	0.000	0.999	0.001
H16.0 Corneal ulcer	0.001	0.999	0.000
L28.2 Other prurigo	0.001	0.999	0.001
L28.1 Prurigo nodularis	0.001	0.999	0.000
M89.83 Other specified disorders of bone (Forearm)	0.000	0.999	0.001
C41.1 Mandible	0.001	0.999	0.000
H44.2 Degenerative myopia	0.001	0.999	0.000
L27.2 Dermatitis due to ingested food	0.000	0.999	0.001
W26.6 Industrial and construction area	0.001	0.999	0.000
L97 Ulcer of lower limb, not elsewhere classified	0.000	0.999	0.001
M19.92 Arthrosis, unspecified (Upper arm)	0.000	0.999	0.001
M94.86 Other specified disorders of cartilage (Lower leg)	0.000	0.999	0.001
F22.0 Delusional disorder	0.000	0.999	0.001
M46.18 Sacroiliitis, not elsewhere classified-Sacral/sacrococ	0.001	0.999	0.000
D29.1 Prostate	0.001	0.999	0.000
K08.8 Other specified disorders of teeth and supporting structures	0.000	0.999	0.001
Q65.8 Other congenital deformities of hip	0.001	0.999	0.000
S67.0 Crushing injury of thumb and other finger(s)	0.001	0.999	0.000
U80.8 Agent resistant to other penicillin-related antibiotic	0.000	0.999	0.001
M19.11 Post-traumatic arthrosis of other joints (Shoulder region)	0.001	0.999	0.000
N76.4 Abscess of vulva	0.000	0.999	0.001
R70 Elevated erythrocyte sedimentation rate and abnormality of plasma viscosity	0.001	0.999	0.000
M19.14 Post-traumatic arthrosis of other joints (Hand)	0.001	0.999	0.000
D86.8 Sarcoidosis of other and combined sites	0.001	0.999	0.000
K51.8 Other ulcerative colitis	0.001	0.999	0.000
M89.8 Other specified disorders of bone	0.000	0.999	0.001
Q14.1 Congenital malformation of retina	0.000	0.999	0.001
M94.88 Other specified disorders of cartilage (Other)	0.000	0.999	0.001
S12.10 Fracture of second cervical vertebra (closed)	0.000	0.999	0.001
C44.7 Skin of lower limb, including hip	0.000	0.999	0.001
D86.0 Sarcoidosis of lung	0.001	0.999	0.000
K86.9 Disease of pancreas, unspecified	0.001	0.999	0.000
N97.1 Female infertility of tubal origin	0.000	0.999	0.001
S56.8 Injury of other and unspecified muscles and tendons at forearm level	0.001	0.999	0.000
S83.6 Sprain and strain of other and unspecified parts of knee	0.001	0.999	0.000
Z95.2 Presence of prosthetic heart valve	0.001	0.999	0.000
S62.80 Fracture of other and unspecified parts of wrist and hand (closed)	0.000	0.999	0.001
S72.10 Pertrochanteric fracture (closed)	0.000	0.999	0.001
S82.00 Fracture of patella (closed)	0.001	0.999	0.000
F79.9 Unspecified mental retardation (Without mention of impairment of behaviour)	0.000	0.999	0.001
H04.1 Other disorders of lachrymal gland	0.001	0.999	0.000
O80.9 Single spontaneous delivery, unspecified	0.000	0.999	0.001
T18.9 Foreign body in alimentary tract, part unspecified	0.000	0.999	0.001
M89.82 Other specified disorders of bone (Upper arm)	0.000	0.999	0.001
M89.80 Other specified disorders of bone (Multiple sites)	0.000	0.999	0.001
B95.7 Other staphylococcus as the cause of diseases classified to other chapters	0.000	0.999	0.001
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms	0.000	0.999	0.001
K50.8 Other Crohn's disease	0.001	0.999	0.000
O46.9 Antepartum haemorrhage, unspecified	0.000	0.999	0.001
R57.9 Shock, unspecified	0.001	0.999	0.000
H05.2 Exophthalmic conditions	0.000	0.999	0.001
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.000	0.999	0.001
I70.0 Atherosclerosis of aorta	0.001	0.999	0.000
L28.0 Lichen simplex chronicus	0.001	0.999	0.000
R09.2 Respiratory arrest	0.000	0.999	0.001
R70.1 Abnormal plasma viscosity	0.001	0.999	0.000
T18.5 Foreign body in anus and rectum	0.000	0.999	0.001
T18 Foreign body in alimentary tract	0.000	0.999	0.001
I70.01 Atherosclerosis of aorta (with gangrene)	0.001	0.999	0.000
M89.84 Other specified disorders of bone (Hand)	0.000	0.999	0.001
R57.1 Hypovolaemic shock	0.001	0.999	0.000
S62.3 Fracture of other metacarpal bone	0.000	0.999	0.001
T18.8 Foreign body in other and multiple parts of alimentary tract	0.000	0.999	0.001
T18.4 Foreign body in colon	0.000	0.999	0.001
M85.99 Disorder of bone density and structure, unspecified (Site unspecified)	0.001	0.999	0.000
Q39.4 Oesophageal web	0.001	0.999	0.000
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.000	0.999	0.001
T93.2 Sequelae of other fractures of lower limb	0.000	0.999	0.001
S82.61 Fracture of lateral malleolus (open)	0.001	0.999	0.000
B08.1 Molluscum contagiosum	0.000	0.999	0.001
G31.2 Degeneration of nervous system due to alcohol	0.000	0.999	0.001
L50.0 Allergic urticaria	0.000	0.999	0.001
T18.3 Foreign body in small intestine	0.000	0.999	0.001
T18.2 Foreign body in stomach	0.000	0.999	0.001

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations