TreeWAS – Variant ID: rs4902100

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
H71 Cholesteatoma of middle ear	0.042	0.958	0.000
H65-H75 Diseases of middle ear and mastoid	0.040	0.960	0.000
H74 Other disorders of middle ear and mastoid	0.039	0.961	0.000
H65.3 Chronic mucoid otitis media	0.039	0.961	0.000
H65 Nonsuppurative otitis media	0.038	0.962	0.000
H69 Other disorders of Eustachian tube	0.038	0.962	0.000
H74.3 Other acquired abnormalities of ear ossicles	0.036	0.963	0.000
H69.9 Eustachian tube disorder, unspecified	0.036	0.964	0.000
H65.2 Chronic serous otitis media	0.034	0.966	0.000
H74.0 Tympanosclerosis	0.034	0.966	0.000
H70 Mastoiditis and related conditions	0.032	0.968	0.000
H69.8 Other specified disorders of Eustachian tube	0.032	0.968	0.000
H65.1 Other acute nonsuppurative otitis media	0.030	0.970	0.000
H68 Eustachian salpingitis and obstruction	0.030	0.970	0.000
H74.4 Polyp of middle ear	0.029	0.971	0.000
H74.9 Disorder of middle ear and mastoid, unspecified	0.029	0.971	0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere	0.029	0.971	0.000
H67 Otitis media in diseases classified elsewhere	0.029	0.971	0.000
H74.1 Adhesive middle ear disease	0.028	0.972	0.000
H69.0 Patulous Eustachian tube	0.027	0.972	0.000
H74.2 Discontinuity and dislocation of ear ossicles	0.027	0.973	0.000
H70.8 Other mastoiditis and related conditions	0.025	0.974	0.000
H70.9 Mastoiditis, unspecified	0.025	0.975	0.000
H74.8 Other specified disorders of middle ear and mastoid	0.025	0.975	0.000
H70.0 Acute mastoiditis	0.023	0.977	0.000
H70.2 Petrositis	0.023	0.977	0.000
H65.4 Other chronic nonsuppurative otitis media	0.023	0.977	0.000
H68.1 Obstruction of Eustachian tube	0.022	0.977	0.000
H65.0 Acute serous otitis media	0.022	0.978	0.000
H73 Other disorders of tympanic membrane	0.022	0.978	0.000
H68.0 Eustachian salpingitis	0.021	0.978	0.000
H67.8 Otitis media in other diseases classified elsewhere	0.021	0.979	0.000
H67.1 Otitis media in viral diseases classified elsewhere	0.021	0.979	0.000
H67.0 Otitis media in bacterial diseases classified elsewhere	0.021	0.979	0.000
H75.8 Other specified disorders of middle ear and mastoid in diseases classified elsewhere	0.021	0.979	0.000
H75.0 Mastoiditis in infectious and parasitic diseases classified elsewhere	0.021	0.979	0.000
I70.20 Atherosclerosis of arteries of extremities (without gangrene)	0.021	0.979	0.000
H70.1 Chronic mastoiditis	0.020	0.980	0.000
H73.9 Disorder of tympanic membrane, unspecified	0.017	0.983	0.000
I70.2 Atherosclerosis of arteries of the extremities	0.017	0.983	0.000
H73.0 Acute myringitis	0.016	0.984	0.000
H65.9 Nonsuppurative otitis media, unspecified	0.016	0.984	0.000
H73.1 Chronic myringitis	0.014	0.986	0.000
I70 Atherosclerosis	0.014	0.986	0.000
H66 Suppurative and unspecified otitis media	0.013	0.987	0.000
I70.0 Atherosclerosis of aorta	0.013	0.987	0.000
I70.00 Atherosclerosis of aorta (without gangrene)	0.013	0.987	0.000
C80.9 Malignant neoplasm, unspecified	0.013	0.987	0.000
I70.21 Atherosclerosis of arteries of extremities (with gangrene)	0.013	0.987	0.000
Z94.8 Other transplanted organ and tissue status	0.013	0.987	0.000
D18.0 Haemangioma, any site	0.013	0.987	0.000
H35.8 Other specified retinal disorders	0.000	0.988	0.012
I70.1 Atherosclerosis of renal artery	0.012	0.988	0.000
H73.8 Other specified disorders of tympanic membrane	0.011	0.989	0.000
H66.0 Acute suppurative otitis media	0.011	0.989	0.000
H35 Other retinal disorders	0.000	0.990	0.010
I70.10 Atherosclerosis of renal artery (without gangrene)	0.010	0.990	0.000
H66.2 Chronic atticoantral suppurative otitis media	0.010	0.990	0.000
I70.8 Atherosclerosis of other arteries	0.010	0.990	0.000
H35.7 Separation of retinal layers	0.000	0.990	0.010
I70.01 Atherosclerosis of aorta (with gangrene)	0.010	0.990	0.000
I70.9 Generalised and unspecified atherosclerosis	0.010	0.990	0.000
H35.6 Retinal haemorrhage	0.000	0.991	0.009
H35.0 Background retinopathy and retinal vascular changes	0.000	0.991	0.009
H35.4 Peripheral retinal degeneration	0.000	0.991	0.009
H35.5 Hereditary retinal dystrophy	0.000	0.991	0.009
H66.1 Chronic tubotympanic suppurative otitis media	0.009	0.991	0.000
J35.8 Other chronic diseases of tonsils and adenoids	0.000	0.991	0.009
I70.11 Atherosclerosis of renal artery (with gangrene)	0.008	0.991	0.000
H66.4 Suppurative otitis media, unspecified	0.008	0.992	0.000
H35.1 Retinopathy of prematurity	0.000	0.992	0.008
H72 Perforation of tympanic membrane	0.008	0.992	0.000
I70.80 Atherosclerosis of other arteries (without gangrene)	0.007	0.992	0.000
I70.81 Atherosclerosis of other arteries (with gangrene)	0.007	0.992	0.000
I70.91 Generalized and unspecified atherosclerosis (with gangrene)	0.007	0.993	0.000
T43.2 Other and unspecified antidepressants	0.007	0.993	0.000
H35.9 Retinal disorder, unspecified	0.000	0.993	0.007
I70.90 Generalized and unspecified atherosclerosis (without gangrene)	0.007	0.993	0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.007	0.993	0.000
J35.0 Chronic tonsillitis	0.000	0.993	0.007
H66.9 Otitis media, unspecified	0.006	0.994	0.000
T43.5 Other and unspecified antipsychotics and neuroleptics	0.006	0.994	0.000
H35.2 Other proliferative retinopathy	0.000	0.994	0.006
T42.4 Benzodiazepines	0.006	0.994	0.000
H72.2 Other marginal perforations of tympanic membrane	0.006	0.994	0.000
D18 Haemangioma and lymphangioma, any site	0.006	0.994	0.000
H26.2 Complicated cataract	0.000	0.994	0.006
T43.3 Phenothiazine antipsychotics and neuroleptics	0.006	0.994	0.000
T45.0 Antiallergic and antiemetic drugs	0.006	0.994	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.006	0.994	0.000
J35 Chronic diseases of tonsils and adenoids	0.000	0.994	0.006
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.006	0.994	0.000
W22.9 Unspecified place	0.006	0.994	0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.006	0.994	0.000
H30-H36 Disorders of choroid and retina	0.000	0.995	0.005
T43.8 Other psychotropic drugs, not elsewhere classified	0.005	0.995	0.000
T43.4 Butyrophenone and thioxanthene neuroleptics	0.005	0.995	0.000
H66.3 Other chronic suppurative otitis media	0.005	0.995	0.000
R90.0 Intracranial space-occupying lesion	0.000	0.995	0.005
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.005	0.995	0.000
T43.9 Psychotropic drug, unspecified	0.005	0.995	0.000
H47.3 Other disorders of optic disk	0.000	0.995	0.005
D18.1 Lymphangioma, any site	0.005	0.995	0.000
C80 Malignant neoplasm without specification of site	0.005	0.995	0.000
H30 Chorioretinal inflammation	0.000	0.995	0.005
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.005	0.995	0.000
T36 Poisoning by systemic antibiotics	0.005	0.995	0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.005	0.995	0.000
J38.3 Other diseases of vocal cords	0.005	0.995	0.000
L50.9 Urticaria, unspecified	0.000	0.995	0.005
T43.6 Psychostimulants with abuse potential	0.005	0.995	0.000
H72.1 Attic perforation of tympanic membrane	0.005	0.995	0.000
H30.9 Chorioretinal inflammation, unspecified	0.000	0.995	0.005
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.005	0.995	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.005	0.995	0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.005	0.995	0.000
T47.1 Other antacids and anti-gastric-secretion drugs	0.005	0.995	0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.005	0.995	0.000
J35.3 Hypertrophy of tonsils with hypertrophy of adenoids	0.000	0.995	0.004
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.004	0.995	0.000
T41 Poisoning by anaesthetics and therapeutic gases	0.004	0.995	0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.004	0.995	0.000
T42.3 Barbiturates	0.004	0.996	0.000
T42.5 Mixed antiepileptics, not elsewhere classified	0.004	0.996	0.000
T42.2 Succinimides and oxazolidinediones	0.004	0.996	0.000
T45.4 Iron and its compounds	0.004	0.996	0.000
T48.5 Anti-common-cold drugs	0.004	0.996	0.000
T42.1 Iminostilbenes	0.004	0.996	0.000
J35.9 Chronic disease of tonsils and adenoids, unspecified	0.000	0.996	0.004
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.004	0.996	0.000
H72.8 Other perforations of tympanic membrane	0.004	0.996	0.000
J35.1 Hypertrophy of tonsils	0.000	0.996	0.004
T36.3 Macrolides	0.004	0.996	0.000
T45.9 Primarily systemic and haematological agent, unspecified	0.004	0.996	0.000
T45.8 Other primarily systemic and haematological agents	0.004	0.996	0.000
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.004	0.996	0.000
T45.6 Fibrinolysis-affecting drugs	0.004	0.996	0.000
T45.3 Enzymes, not elsewhere classified	0.004	0.996	0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.004	0.996	0.000
T45.5 Anticoagulants	0.004	0.996	0.000
T47.4 Other laxatives	0.004	0.996	0.000
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.004	0.996	0.000
T42.0 Hydantoin derivatives	0.004	0.996	0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.004	0.996	0.000
H32 Chorioretinal disorders in diseases classified elsewhere	0.000	0.996	0.004
M81 Osteoporosis without pathological fracture	0.004	0.996	0.000
T46.5 Other antihypertensive drugs, not elsewhere classified	0.004	0.996	0.000
H40.2 Primary angle-closure glaucoma	0.004	0.996	0.000
H34 Retinal vascular occlusions	0.000	0.996	0.004
M80-M85 Disorders of bone density and structure	0.004	0.996	0.000
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.004	0.996	0.000
T47.8 Other agents primarily affecting the gastro-intestinal system	0.004	0.996	0.000
T47.7 Emetics	0.004	0.996	0.000
T47.5 Digestants	0.004	0.996	0.000
T47.3 Saline and osmotic laxatives	0.004	0.996	0.000
H30.2 Posterior cyclitis	0.000	0.996	0.004
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.004	0.996	0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.004	0.996	0.000
T47.6 Antidiarrhoeal drugs	0.004	0.996	0.000
M85 Other disorders of bone density and structure	0.004	0.996	0.000
T43.0 Tricyclic and tetracyclic antidepressants	0.004	0.996	0.000
H47 Other disorders of optic [2nd] nerve and visual pathways	0.000	0.996	0.004
T37.8 Other specified systemic anti-infectives and antiparasitics	0.004	0.996	0.000
T46.4 Angiotensin-converting-enzyme inhibitors	0.004	0.996	0.000
T50.6 Antidotes and chelating agents, not elsewhere classified	0.004	0.996	0.000
H30.8 Other chorioretinal inflammations	0.000	0.996	0.004
H30.1 Disseminated chorioretinal inflammation	0.000	0.996	0.004
H30.0 Focal chorioretinal inflammation	0.000	0.996	0.004
T46.1 Calcium-channel blockers	0.004	0.996	0.000
M81.9 Osteoporosis, unspecified	0.004	0.996	0.000
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.004	0.996	0.000
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.004	0.996	0.000
T48.4 Expectorants	0.004	0.996	0.000
T48.3 Antitussives	0.004	0.996	0.000
T48.2 Other and unspecified agents primarily acting on muscles	0.004	0.996	0.000
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.004	0.996	0.000
T48.0 Oxytocic drugs	0.004	0.996	0.000
J02.9 Acute pharyngitis, unspecified	0.000	0.996	0.004
T36.9 Systemic antibiotic, unspecified	0.004	0.996	0.000
T36.7 Antifungal antibiotics, systemically used	0.004	0.996	0.000
T36.6 Rifamycins	0.004	0.996	0.000
T36.5 Aminoglycosides	0.004	0.996	0.000
T36.2 Chloramphenicol group	0.004	0.996	0.000
M80 Osteoporosis with pathological fracture	0.004	0.996	0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.004	0.996	0.000
T50.4 Drugs affecting uric acid metabolism	0.004	0.996	0.000
M85.89 Other specified disorders of bone density and structure (Site unspecified)	0.004	0.996	0.000
J38.1 Polyp of vocal cord and larynx	0.004	0.996	0.000
M80.9 Unspecified osteoporosis with pathological fracture	0.004	0.996	0.000
M81.99 Osteoporosis, unspecified (Site unspecified)	0.004	0.996	0.000
Q76.4 Other congenital malformations of spine, not associated with scoliosis	0.004	0.996	0.000
T45.1 Antineoplastic and immunosuppressive drugs	0.004	0.996	0.000
T47.2 Stimulant laxatives	0.004	0.996	0.000
T36.0 Penicillins	0.004	0.996	0.000
T50.7 Analeptics and opioid receptor antagonists	0.004	0.996	0.000
T50.5 Appetite depressants	0.004	0.996	0.000
T50.3 Electrolytic, caloric and water-balance agents	0.004	0.996	0.000
T50.1 Loop [high-ceiling] diuretics	0.004	0.996	0.000
T50.0 Mineralocorticoids and their antagonists	0.004	0.996	0.000
M85.8 Other specified disorders of bone density and structure	0.004	0.996	0.000
T46.8 Antivaricose drugs, including sclerosing agents	0.004	0.996	0.000
T46.7 Peripheral vasodilators	0.004	0.996	0.000
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.003	0.996	0.000
T37.5 Antiviral drugs	0.003	0.996	0.000
T37.4 Anthelminthics	0.003	0.996	0.000
T37.3 Other antiprotozoal drugs	0.003	0.996	0.000
T37.2 Antimalarials and drugs acting on other blood protozoa	0.003	0.996	0.000
T37.1 Antimycobacterial drugs	0.003	0.996	0.000
T37.0 Sulphonamides	0.003	0.996	0.000
T47.0 Histamine H(2)-receptor antagonists	0.003	0.996	0.000
H31 Other disorders of choroid	0.000	0.996	0.004
W22 Striking against or struck by other objects	0.004	0.996	0.000
Q65.8 Other congenital deformities of hip	0.004	0.996	0.000
R90.8 Other abnormal findings on diagnostic imaging of central nervous system	0.000	0.996	0.004
T45.2 Vitamins, not elsewhere classified	0.003	0.996	0.000
T50.8 Diagnostic agents	0.003	0.996	0.000
H36 Retinal disorders in diseases classified elsewhere	0.000	0.996	0.004
H46 Optic neuritis	0.000	0.996	0.004
R90 Abnormal findings on diagnostic imaging of central nervous system	0.000	0.996	0.004
M81.95 Osteoporosis, unspecified (Pelvic region and thigh)	0.004	0.996	0.000
M81.3 Postsurgical malabsorption osteoporosis	0.004	0.996	0.000
T38.8 Other and unspecified hormones and their synthetic substitutes	0.003	0.996	0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.003	0.996	0.000
J35.2 Hypertrophy of adenoids	0.000	0.996	0.003
T36.8 Other systemic antibiotics	0.003	0.996	0.000
T50.9 Other and unspecified drugs, medicaments and biological substances	0.004	0.996	0.000
H72.0 Central perforation of tympanic membrane	0.003	0.996	0.000
T41.5 Therapeutic gases	0.003	0.996	0.000
T41.4 Anaesthetic, unspecified	0.003	0.996	0.000
T41.3 Local anaesthetics	0.003	0.996	0.000
T41.1 Intravenous anaesthetics	0.003	0.996	0.000
T41.0 Inhaled anaesthetics	0.003	0.996	0.000
T46.3 Coronary vasodilators, not elsewhere classified	0.003	0.996	0.000
T48.6 Antiasthmatics, not elsewhere classified	0.003	0.996	0.000
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.003	0.996	0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.003	0.996	0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.003	0.996	0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.003	0.996	0.000
T44.1 Other parasympathomimetics [cholinergics]	0.003	0.996	0.000
T44.0 Anticholinesterase agents	0.003	0.996	0.000
T49.9 Topical agent, unspecified	0.003	0.996	0.000
T49.8 Other topical agents	0.003	0.996	0.000
T49.7 Dental drugs, topically applied	0.003	0.996	0.000
T49.6 Otorhinolaryngological drugs and preparations	0.003	0.996	0.000
T49.5 Ophthalmological drugs and preparations	0.003	0.996	0.000
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.003	0.996	0.000
T49.3 Emollients, demulcents and protectants	0.003	0.996	0.000
T49.2 Local astringents and local detergents	0.003	0.996	0.000
T49.1 Antipruritics	0.003	0.996	0.000
H34.2 Other retinal artery occlusions	0.000	0.997	0.003
T41.2 Other and unspecified general anaesthetics	0.003	0.997	0.000
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.003	0.997	0.000
H49.2 Sixth [abducent] nerve palsy	0.000	0.997	0.003
M81.4 Drug-induced osteoporosis	0.003	0.997	0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.003	0.997	0.000
G63.2 Diabetic polyneuropathy	0.003	0.997	0.000
M82 Osteoporosis in diseases classified elsewhere	0.003	0.997	0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.003	0.997	0.000
T36.4 Tetracyclines	0.003	0.997	0.000
M80.99 Unspecified osteoporosis with pathological fracture (Site unspecified)	0.003	0.997	0.000
M85.0 Fibrous dysplasia (monostotic)	0.003	0.997	0.000
T38.9 Other and unspecified hormone antagonists	0.003	0.997	0.000
T38.7 Androgens and anabolic congeners	0.003	0.997	0.000
T38.5 Other oestrogens and progestogens	0.003	0.997	0.000
T38.4 Oral contraceptives	0.003	0.997	0.000
T38.2 Antithyroid drugs	0.003	0.997	0.000
M84.4 Pathological fracture, not elsewhere classified	0.003	0.997	0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.003	0.997	0.000
M85.87 Other specified disorders of bone density and structure (Ankle and foot)	0.003	0.997	0.000
M81.30 Postsurgical malabsorption osteoporosis (Multiple sites)	0.003	0.997	0.000
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.003	0.997	0.000
M83 Adult osteomalacia	0.003	0.997	0.000
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.003	0.997	0.000
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.003	0.997	0.000
W13.9 Unspecified place	0.003	0.997	0.000
T40.5 Cocaine	0.003	0.997	0.000
H33.5 Other retinal detachments	0.000	0.997	0.003
W22.2 School, other institution and public administrative area	0.003	0.997	0.000
M81.96 Osteoporosis, unspecified (Lower leg)	0.003	0.997	0.000
H47.0 Disorders of optic nerve, not elsewhere classified	0.000	0.997	0.003
H46-H48 Disorders of optic nerve and visual pathways	0.000	0.997	0.003
M81.93 Osteoporosis, unspecified (Forearm)	0.003	0.997	0.000
M84 Disorders of continuity of bone	0.003	0.997	0.000
M85.80 Other specified disorders of bone density and structure (Multiple sites)	0.003	0.997	0.000
M81.92 Osteoporosis, unspecified (Upper arm)	0.003	0.997	0.000
D37.4 Colon	0.003	0.997	0.000
M81.8 Other osteoporosis	0.003	0.997	0.000
M81.1 Postoophorectomy osteoporosis	0.003	0.997	0.000
Q76 Congenital malformations of spine and bony thorax	0.003	0.997	0.000
M80.90 Unspecified osteoporosis with pathological fracture (Multiple sites)	0.003	0.997	0.000
H31.0 Chorioretinal scars	0.000	0.997	0.003
H32.8 Other chorioretinal disorders in diseases classified elsewhere	0.000	0.997	0.003
H32.0 Chorioretinal inflammation in infectious and parasitic diseases classified elsewhere	0.000	0.997	0.003
H47.1 Papilloedema, unspecified	0.000	0.997	0.003
M81.6 Localised osteoporosis [Lequesne]	0.003	0.997	0.000
M81.5 Idiopathic osteoporosis	0.003	0.997	0.000
M85.2 Hyperostosis of skull	0.003	0.997	0.000
M81.94 Osteoporosis, unspecified (Hand)	0.003	0.997	0.000
H34.8 Other retinal vascular occlusions	0.000	0.997	0.003
T40.3 Methadone	0.003	0.997	0.000
W22.5 Trade and service area	0.003	0.997	0.000
H34.0 Transient retinal artery occlusion	0.000	0.997	0.003
M80.0 Postmenopausal osteoporosis with pathological fracture	0.003	0.997	0.000
M84.2 Delayed union of fracture	0.003	0.997	0.000
M85.6 Other cyst of bone	0.003	0.997	0.000
M81.49 Drug-induced osteoporosis (Site unspecified)	0.003	0.997	0.000
M84.42 Pathological fracture, not elsewhere classified (Upper arm)	0.003	0.997	0.000
H33 Retinal detachments and breaks	0.000	0.997	0.003
M85.9 Disorder of bone density and structure, unspecified	0.003	0.997	0.000
M85.5 Aneurysmal bone cyst	0.003	0.997	0.000
M85.3 Osteitis condensans	0.003	0.997	0.000
M85.1 Skeletal fluorosis	0.003	0.997	0.000
M80.95 Unspecified osteoporosis with pathological fracture (Pelvic region and thigh)	0.003	0.997	0.000
H47.7 Disorder of visual pathways, unspecified	0.000	0.997	0.003
H47.6 Disorders of visual cortex	0.000	0.997	0.003
H47.4 Disorders of optic chiasm	0.000	0.997	0.003
M80.98 Unspecified osteoporosis with pathological fracture (Other)	0.003	0.997	0.000
M85.81 Other specified disorders of bone density and structure (Shoulder region)	0.003	0.997	0.000
H34.9 Retinal vascular occlusion, unspecified	0.000	0.997	0.003
Q76.0 Spina bifida occulta	0.003	0.997	0.000
T38.0 Glucocorticoids and synthetic analogues	0.003	0.997	0.000
M81.0 Postmenopausal osteoporosis	0.003	0.997	0.000
M82.1 Osteoporosis in endocrine disorders	0.003	0.997	0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.003	0.997	0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.003	0.997	0.000
M84.45 Pathological fracture, not elsewhere classified (Pelvic region and thigh)	0.003	0.997	0.000
M80.1 Postoophorectomy osteoporosis with pathological fracture	0.003	0.997	0.000
N39.9 Disorder of urinary system, unspecified	0.003	0.997	0.000
M80.4 Drug-induced osteoporosis with pathological fracture	0.003	0.997	0.000
M80.3 Postsurgical malabsorption osteoporosis with pathological fracture	0.003	0.997	0.000
M80.2 Osteoporosis of disuse with pathological fracture	0.003	0.997	0.000
M85.4 Solitary bone cyst	0.003	0.997	0.000
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.003	0.997	0.000
T40.8 Lysergide [LSD]	0.003	0.997	0.000
T40.7 Cannabis (derivatives)	0.003	0.997	0.000
T40.0 Opium	0.003	0.997	0.000
M81.91 Osteoporosis, unspecified (Shoulder region)	0.003	0.997	0.000
H47.5 Disorders of other visual pathways	0.000	0.997	0.003
T40.6 Other and unspecified narcotics	0.003	0.997	0.000
M80.97 Unspecified osteoporosis with pathological fracture (Ankle and foot)	0.003	0.997	0.000
M80.96 Unspecified osteoporosis with pathological fracture (Lower leg)	0.003	0.997	0.000
M80.94 Unspecified osteoporosis with pathological fracture (Hand)	0.003	0.997	0.000
M80.93 Unspecified osteoporosis with pathological fracture (Forearm)	0.003	0.997	0.000
M80.92 Unspecified osteoporosis with pathological fracture (Upper arm)	0.003	0.997	0.000
M80.91 Unspecified osteoporosis with pathological fracture (Shoulder region)	0.003	0.997	0.000
Q76.5 Cervical rib	0.003	0.997	0.000
M84.41 Pathological fracture, not elsewhere classified (Shoulder region)	0.003	0.997	0.000
H31.3 Choroidal haemorrhage and rupture	0.000	0.997	0.003
M85.84 Other specified disorders of bone density and structure (Hand)	0.003	0.997	0.000
F00.9 Dementia in Alzheimer's disease, unspecified	0.003	0.997	0.000
H31.4 Choroidal detachment	0.000	0.997	0.003
H31.2 Hereditary choroidal dystrophy	0.000	0.997	0.003
M80.8 Other osteoporosis with pathological fracture	0.003	0.997	0.000
W22.8 Other specified place	0.003	0.997	0.000
W22.6 Industrial and construction area	0.003	0.997	0.000
W22.4 Street and highway	0.003	0.997	0.000
W22.0 Home	0.003	0.997	0.000
W22.7 Farm	0.003	0.997	0.000
W22.3 Sports and athletics area	0.003	0.997	0.000
W22.1 Residential institution	0.003	0.997	0.000
M85.03 Fibrous dysplasia (monostotic) (Forearm)	0.003	0.997	0.000
M85.67 Other cyst of bone (Ankle and foot)	0.003	0.997	0.000
H33.1 Retinoschisis and retinal cysts	0.000	0.997	0.003
H40.0 Glaucoma suspect	0.003	0.997	0.000
M83.3 Adult osteomalacia due to malnutrition	0.003	0.997	0.000
M81.39 Postsurgical malabsorption osteoporosis (Site unspecified)	0.003	0.997	0.000
M81.38 Postsurgical malabsorption osteoporosis (Other)	0.003	0.997	0.000
M81.37 Postsurgical malabsorption osteoporosis (Ankle and foot)	0.003	0.997	0.000
M81.36 Postsurgical malabsorption osteoporosis (Lower leg)	0.003	0.997	0.000
M81.35 Postsurgical malabsorption osteoporosis (Pelvic region and thigh)	0.003	0.997	0.000
M81.34 Postsurgical malabsorption osteoporosis (Hand)	0.003	0.997	0.000
M81.33 Postsurgical malabsorption osteoporosis (Forearm)	0.003	0.997	0.000
M81.32 Postsurgical malabsorption osteoporosis (Upper arm)	0.003	0.997	0.000
M81.31 Postsurgical malabsorption osteoporosis (Shoulder region)	0.003	0.997	0.000
H36.8 Other retinal disorders in diseases classified elsewhere	0.000	0.997	0.003
M81.2 Osteoporosis of disuse	0.003	0.997	0.000
M82.10 Osteoporosis in endocrine disorders (Multiple sites)	0.003	0.997	0.000
M85.82 Other specified disorders of bone density and structure (Upper arm)	0.003	0.997	0.000
C80.0 Malignant neoplasm, primary site unknown, so stated	0.003	0.997	0.000
M85.00 Fibrous dysplasia (monostotic) (Multiple sites)	0.003	0.997	0.000
M85.86 Other specified disorders of bone density and structure (Lower leg)	0.003	0.997	0.000
M83.8 Other adult osteomalacia	0.003	0.997	0.000
M84.48 Pathological fracture, not elsewhere classified (Other)	0.003	0.997	0.000
M80.5 Idiopathic osteoporosis with pathological fracture	0.003	0.997	0.000
T40.1 Heroin	0.003	0.997	0.000
H31.9 Disorder of choroid, unspecified	0.000	0.997	0.003
T40.2 Other opioids	0.003	0.997	0.000
M81.48 Drug-induced osteoporosis (Other)	0.003	0.997	0.000
M81.47 Drug-induced osteoporosis (Ankle and foot)	0.003	0.997	0.000
M81.46 Drug-induced osteoporosis (Lower leg)	0.003	0.997	0.000
M81.45 Drug-induced osteoporosis (Pelvic region and thigh)	0.003	0.997	0.000
M81.44 Drug-induced osteoporosis (Hand)	0.003	0.997	0.000
M81.43 Drug-induced osteoporosis (Forearm)	0.003	0.997	0.000
M81.42 Drug-induced osteoporosis (Upper arm)	0.003	0.997	0.000
M81.41 Drug-induced osteoporosis (Shoulder region)	0.003	0.997	0.000
M81.98 Osteoporosis, unspecified (Other)	0.003	0.997	0.000
M82.8 Osteoporosis in other diseases classified elsewhere	0.003	0.997	0.000
M82.0 Osteoporosis in multiple myelomatosis	0.003	0.997	0.000
M82.3 Osteoporosis in diseases classified elsewhere, Forearm	0.003	0.997	0.000
M83.9 Adult osteomalacia, unspecified	0.003	0.997	0.000
Q65 Congenital deformities of hip	0.003	0.997	0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)	0.003	0.997	0.000
M84.26 Delayed union of fracture (Lower leg)	0.003	0.997	0.000
M84.49 Pathological fracture, not elsewhere classified (Site unspecified)	0.003	0.997	0.000
M84.47 Pathological fracture, not elsewhere classified (Ankle and foot)	0.003	0.997	0.000
M84.46 Pathological fracture, not elsewhere classified (Lower leg)	0.003	0.997	0.000
M84.44 Pathological fracture, not elsewhere classified (Hand)	0.003	0.997	0.000
M84.43 Pathological fracture, not elsewhere classified (Forearm)	0.003	0.997	0.000
M85.09 Fibrous dysplasia (monostotic) (Site unspecified)	0.003	0.997	0.000
M85.07 Fibrous dysplasia (monostotic) (Ankle and foot)	0.003	0.997	0.000
M85.06 Fibrous dysplasia (monostotic) (Lower leg)	0.003	0.997	0.000
M85.05 Fibrous dysplasia (monostotic) (Pelvic region and thigh)	0.003	0.997	0.000
M85.04 Fibrous dysplasia (monostotic) (Hand)	0.003	0.997	0.000
M85.02 Fibrous dysplasia (monostotic) (Upper arm)	0.003	0.997	0.000
M85.01 Fibrous dysplasia (monostotic) (Shoulder region)	0.003	0.997	0.000
M81.97 Osteoporosis, unspecified (Ankle and foot)	0.003	0.997	0.000
M84.25 Delayed union of fracture (Pelvic region and thigh)	0.003	0.997	0.000
M84.22 Delayed union of fracture (Upper arm)	0.003	0.997	0.000
M85.08 Fibrous dysplasia (monostotic) (Other)	0.003	0.997	0.000
M85.20 Hyperostosis of skull-Mult sites	0.003	0.997	0.000
H31.8 Other specified disorders of choroid	0.000	0.997	0.003
H40.1 Primary open-angle glaucoma	0.003	0.997	0.000
M83.5 Other drug-induced osteomalacia in adults	0.002	0.997	0.000
M83.4 Aluminum bone disease	0.002	0.997	0.000
M83.2 Adult osteomalacia due to malabsorption	0.002	0.997	0.000
M83.0 Puerperal osteomalacia	0.002	0.997	0.000
M81.80 Other osteoporosis (Multiple sites)	0.002	0.997	0.000
M85.99 Disorder of bone density and structure, unspecified (Site unspecified)	0.002	0.997	0.000
T38.1 Thyroid hormones and substitutes	0.002	0.997	0.000
M81.40 Drug-induced osteoporosis (Multiple sites)	0.003	0.997	0.000
M84.21 Delayed union of fracture (Shoulder region)	0.002	0.997	0.000
M85.83 Other specified disorders of bone density and structure (Forearm)	0.002	0.997	0.000
M80.00 Postmenopausal osteoporosis with pathological fracture (Multiple sites)	0.003	0.997	0.000
H31.1 Choroidal degeneration	0.000	0.997	0.002
M84.9 Disorder of continuity of bone, unspecified	0.002	0.997	0.000
H48 Disorders of optic [2nd] nerve and visual pathways in diseases classified elsewhere	0.000	0.997	0.002
M81.10 Postoophorectomy osteoporosis (Multiple sites)	0.002	0.997	0.000
M81.88 Other osteoporosis (Other)	0.002	0.997	0.000
M81.87 Other osteoporosis (Ankle and foot)	0.002	0.997	0.000
M81.86 Other osteoporosis (Lower leg)	0.002	0.997	0.000
M81.85 Other osteoporosis (Pelvic region and thigh)	0.002	0.997	0.000
M81.84 Other osteoporosis (Hand)	0.002	0.997	0.000
M81.83 Other osteoporosis (Forearm)	0.002	0.997	0.000
M81.82 Other osteoporosis (Upper arm)	0.002	0.997	0.000
M81.81 Other osteoporosis (Shoulder region)	0.002	0.997	0.000
M81.00 Postmenopausal osteoporosis (Multiple sites)	0.002	0.997	0.000
M81.19 Postoophorectomy osteoporosis (Site unspecified)	0.002	0.997	0.000
M81.18 Postoophorectomy osteoporosis (Other)	0.002	0.997	0.000
M81.17 Postoophorectomy osteoporosis (Ankle and foot)	0.002	0.997	0.000
M81.16 Postoophorectomy osteoporosis (Lower leg)	0.002	0.997	0.000
M81.15 Postoophorectomy osteoporosis (Pelvic region and thigh)	0.002	0.997	0.000
M81.14 Postoophorectomy osteoporosis (Hand)	0.002	0.997	0.000
M81.13 Postoophorectomy osteoporosis (Forearm)	0.002	0.997	0.000
M81.12 Postoophorectomy osteoporosis (Upper arm)	0.002	0.997	0.000
M81.11 Postoophorectomy osteoporosis (Shoulder region)	0.002	0.997	0.000
M85.85 Other specified disorders of bone density and structure (Pelvic region and thigh)	0.002	0.997	0.000
Q76.9 Congenital malformation of bony thorax, unspecified	0.002	0.997	0.000
Q76.8 Other congenital malformations of bony thorax	0.002	0.997	0.000
Q76.7 Congenital malformation of sternum	0.002	0.997	0.000
Q76.6 Other congenital malformations of ribs	0.002	0.997	0.000
Q76.3 Congenital scoliosis due to congenital bony malformation	0.002	0.997	0.000
Q76.2 Congenital spondylolisthesis	0.002	0.997	0.000
J38 Diseases of vocal cords and larynx, not elsewhere classified	0.003	0.997	0.000
M81.59 Idiopathic osteoporosis (Site unspecified)	0.002	0.997	0.000
M81.58 Idiopathic osteoporosis (Other)	0.002	0.997	0.000
M81.57 Idiopathic osteoporosis (Ankle and foot)	0.002	0.997	0.000
M81.56 Idiopathic osteoporosis (Lower leg)	0.002	0.997	0.000
M81.55 Idiopathic osteoporosis (Pelvic region and thigh)	0.002	0.997	0.000
M81.54 Idiopathic osteoporosis (Hand)	0.002	0.997	0.000
M81.53 Idiopathic osteoporosis (Forearm)	0.002	0.997	0.000
M81.52 Idiopathic osteoporosis (Upper arm)	0.002	0.997	0.000
M81.51 Idiopathic osteoporosis (Shoulder region)	0.002	0.997	0.000
M81.50 Idiopathic osteoporosis (Multiple sites)	0.002	0.997	0.000
M81.69 Localized osteoporosis [Lequesne] (Site unspecified)	0.002	0.997	0.000
M81.68 Localized osteoporosis [Lequesne] (Other)	0.002	0.997	0.000
M81.67 Localized osteoporosis [Lequesne] (Ankle and foot)	0.002	0.997	0.000
M81.66 Localized osteoporosis [Lequesne] (Lower leg)	0.002	0.997	0.000
M81.65 Localized osteoporosis [Lequesne] (Pelvic region and thigh)	0.002	0.997	0.000
M81.64 Localized osteoporosis [Lequesne] (Hand)	0.002	0.997	0.000
M81.63 Localized osteoporosis [Lequesne] (Forearm)	0.002	0.997	0.000
M81.62 Localized osteoporosis [Lequesne] (Upper arm)	0.002	0.997	0.000
M81.61 Localized osteoporosis [Lequesne] (Shoulder region)	0.002	0.997	0.000
M81.60 Localized osteoporosis [Lequesne] (Multiple sites)	0.002	0.997	0.000
M81.89 Other osteoporosis (Site unspecified)	0.002	0.997	0.000
M83.30 Adult osteomalacia due to malnutrition (Multiple sites)	0.002	0.997	0.000
M85.29 Hyperostosis of skull-Site unspec	0.002	0.997	0.000
M85.28 Hyperostosis of skull-Other	0.002	0.997	0.000
M85.27 Hyperostosis of skull-Ankle/Foot	0.002	0.997	0.000
M85.26 Hyperostosis of skull-Lower Leg	0.002	0.997	0.000
M85.25 Hyperostosis of skull-Pelvic/Thigh	0.002	0.997	0.000
M85.24 Hyperostosis of skull-Hand	0.002	0.997	0.000
M85.23 Hyperostosis of skull-Forearm	0.002	0.997	0.000
M85.21 Hyperostosis of skull-Shldr region	0.002	0.997	0.000
M85.66 Other cyst of bone (Lower leg)	0.002	0.997	0.000
M85.98 Disorder of bone density and structure, unspecified (Other)	0.002	0.997	0.000
Q76.1 Klippel-Feil syndrome	0.002	0.997	0.000
M84.40 Pathological fracture, not elsewhere classified (Multiple sites)	0.002	0.997	0.000
M85.69 Other cyst of bone (Site unspecified)	0.002	0.997	0.000
M85.63 Other cyst of bone (Forearm)	0.002	0.997	0.000
M85.62 Other cyst of bone (Upper arm)	0.002	0.997	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations