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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs492478
log Bayes Factor = 3.43239
Chromosome 5   position 3,939,476  (GRCh37) Explore rs492478 on Ensembl!
Variant rs492478 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
I25.8 Other forms of chronic ischaemic heart disease
0.998 0.002 0.000
I25 Chronic ischaemic heart disease
0.998 0.002 0.000
I25.1 Atherosclerotic heart disease
0.987 0.013 0.000
I25.2 Old myocardial infarction
0.977 0.023 0.000
I20-I25 Ischaemic heart diseases
0.904 0.096 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.854 0.146 0.000
I21 Acute myocardial infarction
0.851 0.149 0.000
I21.2 Acute transmural myocardial infarction of other sites
0.817 0.183 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.793 0.207 0.000
I20 Angina pectoris
0.771 0.229 0.000
I22 Subsequent myocardial infarction
0.746 0.254 0.000
I25.6 Silent myocardial ischaemia
0.716 0.284 0.000
Z95.1 Presence of aortocoronary bypass graft
0.711 0.289 0.000
I20.0 Unstable angina
0.681 0.319 0.000
I22.9 Subsequent myocardial infarction of unspecified site
0.678 0.322 0.000
I23 Certain current complications following acute myocardial infarction
0.661 0.339 0.000
I21.4 Acute subendocardial myocardial infarction
0.646 0.354 0.000
I25.4 Coronary artery aneurysm
0.621 0.379 0.000
I20.8 Other forms of angina pectoris
0.618 0.382 0.000
I21.X Presumed acute myicardial infaction (unconfirmed)
0.610 0.390 0.000
I21.3 Acute transmural myocardial infarction of unspecified site
0.610 0.390 0.000
I25.3 Aneurysm of heart
0.608 0.391 0.000
I21.9 Acute myocardial infarction, unspecified
0.605 0.395 0.000
I24 Other acute ischaemic heart diseases
0.604 0.396 0.000
I21.1 Acute transmural myocardial infarction of inferior wall
0.602 0.398 0.000
I25.5 Ischaemic cardiomyopathy
0.585 0.415 0.000
Z95 Presence of cardiac and vascular implants and grafts
0.578 0.422 0.000
I21.0 Acute transmural myocardial infarction of anterior wall
0.547 0.453 0.000
I22.0 Subsequent myocardial infarction of anterior wall
0.540 0.460 0.000
Z95.5 Presence of coronary angioplasty implant and graft
0.532 0.468 0.000
I22.8 Subsequent myocardial infarction of other sites
0.530 0.470 0.000
Z95.8 Presence of other cardiac and vascular implants and grafts
0.526 0.474 0.000
I20.9 Angina pectoris, unspecified
0.525 0.475 0.000
Z95.9 Presence of cardiac and vascular implant and graft, unspecified
0.492 0.508 0.000
I23.8 Other current complications following acute myocardial infarction
0.486 0.514 0.000
Z95.3 Presence of xenogenic heart valve
0.483 0.517 0.000
I20.1 Angina pectoris with documented spasm
0.474 0.525 0.000
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction
0.474 0.526 0.000
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction
0.474 0.526 0.000
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction
0.474 0.526 0.000
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction
0.474 0.526 0.000
I23.2 Ventricular septal defect as current complication following acute myocardial infarction
0.474 0.526 0.000
I23.1 Atrial septal defect as current complication following acute myocardial infarction
0.474 0.526 0.000
I23.0 Haemopericardium as current complication following acute myocardial infarction
0.474 0.526 0.000
Z95.4 Presence of other heart-valve replacement
0.468 0.532 0.000
I24.8 Other forms of acute ischaemic heart disease
0.449 0.551 0.000
I24.9 Acute ischaemic heart disease, unspecified
0.435 0.565 0.000
I24.1 Dressler's syndrome
0.433 0.567 0.000
I22.1 Subsequent myocardial infarction of inferior wall
0.389 0.611 0.000
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.363 0.637 0.000
L72.0 Epidermal cyst
0.000 0.857 0.143
Z95.2 Presence of prosthetic heart valve
0.115 0.885 0.000
Z95.0 Presence of cardiac pacemaker
0.069 0.931 0.000
K50 Crohn's disease [regional enteritis]
0.000 0.966 0.034
K50.9 Crohn's disease, unspecified
0.000 0.966 0.034
K50.0 Crohn's disease of small intestine
0.000 0.966 0.033
K50.1 Crohn's disease of large intestine
0.000 0.967 0.033
Chapter IX Diseases of the circulatory system
0.028 0.972 0.000
L72 Follicular cysts of skin and subcutaneous tissue
0.000 0.974 0.026
I95-I99 Other and unspecified disorders of the circulatory system
0.026 0.974 0.000
I98 Other disorders of circulatory system in diseases classified elsewhere
0.024 0.976 0.000
K50.8 Other Crohn's disease
0.000 0.977 0.023
I05-I09 Chronic rheumatic heart diseases
0.022 0.978 0.000
I98.3 Oesophageal varices with bleeding in diseases classified elsewhere
0.021 0.978 0.000
I98.2 Oesophageal varices in diseases classified elsewhere
0.021 0.979 0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.020 0.980 0.000
I00-I02 Acute rheumatic fever
0.020 0.980 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.019 0.981 0.000
I99 Other and unspecified disorders of circulatory system
0.019 0.981 0.000
I08 Multiple valve diseases
0.019 0.981 0.000
L72.2 Steatocystoma multiplex
0.000 0.981 0.019
I95 Hypotension
0.019 0.981 0.000
I95.1 Orthostatic hypotension
0.019 0.981 0.000
I08.1 Disorders of both mitral and tricuspid valves
0.018 0.982 0.000
I98.8 Other specified disorders of circulatory system in diseases classified elsewhere
0.017 0.982 0.000
I98.1 Cardiovascular disorders in other infectious and parasitic diseases classified elsewhere
0.017 0.982 0.000
I98.0 Cardiovascular syphilis
0.017 0.982 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.018 0.982 0.000
I07 Rheumatic tricuspid valve diseases
0.017 0.983 0.000
I08.2 Disorders of both aortic and tricuspid valves
0.017 0.983 0.000
I97.1 Other functional disturbances following cardiac surgery
0.016 0.983 0.000
I74 Arterial embolism and thrombosis
0.016 0.984 0.000
I09 Other rheumatic heart diseases
0.016 0.984 0.000
I71 Aortic aneurysm and dissection
0.016 0.984 0.000
I27 Other pulmonary heart diseases
0.016 0.984 0.000
I06 Rheumatic aortic valve diseases
0.016 0.984 0.000
I97.8 Other postprocedural disorders of circulatory system, not elsewhere classified
0.016 0.984 0.000
I27.2 Other secondary pulmonary hypertension
0.015 0.985 0.000
I71.9 Aortic aneurysm of unspecified site, without mention of rupture
0.015 0.985 0.000
I10-I15 Hypertensive diseases
0.015 0.985 0.000
I97.9 Postprocedural disorder of circulatory system, unspecified
0.015 0.985 0.000
I97.0 Postcardiotomy syndrome
0.015 0.985 0.000
L60-L75 Disorders of skin appendages
0.000 0.985 0.015
I02 Rheumatic chorea
0.014 0.985 0.000
I01 Rheumatic fever with heart involvement
0.014 0.985 0.000
I00 Rheumatic fever without mention of heart involvement
0.014 0.985 0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.015 0.985 0.000
L72.9 Follicular cyst of skin and subcutaneous tissue, unspecified
0.000 0.986 0.014
I28 Other diseases of pulmonary vessels
0.014 0.986 0.000
I07.1 Tricuspid insufficiency
0.014 0.986 0.000
I08.9 Multiple valve disease, unspecified
0.014 0.986 0.000
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.014 0.986 0.000
I71.0 Dissection of aorta [any part]
0.014 0.986 0.000
I95.0 Idiopathic hypotension
0.014 0.986 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.013 0.986 0.000
I74.0 Embolism and thrombosis of abdominal aorta
0.013 0.986 0.000
I97.2 Postmastectomy lymphoedema syndrome
0.013 0.987 0.000
L60 Nail disorders
0.000 0.987 0.013
I74.9 Embolism and thrombosis of unspecified artery
0.013 0.987 0.000
I07.9 Tricuspid valve disease, unspecified
0.012 0.987 0.000
I07.8 Other tricuspid valve diseases
0.012 0.987 0.000
I07.2 Tricuspid stenosis with insufficiency
0.012 0.987 0.000
I07.0 Tricuspid stenosis
0.012 0.987 0.000
L72.8 Other follicular cysts of skin and subcutaneous tissue
0.000 0.987 0.012
I74.8 Embolism and thrombosis of other arteries
0.012 0.988 0.000
I15 Secondary hypertension
0.012 0.988 0.000
I95.8 Other hypotension
0.012 0.988 0.000
I09.9 Rheumatic heart disease, unspecified
0.012 0.988 0.000
L60.0 Ingrowing nail
0.000 0.988 0.012
I74.5 Embolism and thrombosis of iliac artery
0.012 0.988 0.000
I74.4 Embolism and thrombosis of arteries of extremities, unspecified
0.012 0.988 0.000
I74.1 Embolism and thrombosis of other and unspecified parts of aorta
0.012 0.988 0.000
L65 Other nonscarring hair loss
0.000 0.988 0.012
I09.8 Other specified rheumatic heart diseases
0.012 0.988 0.000
I09.2 Chronic rheumatic pericarditis
0.012 0.988 0.000
I09.1 Rheumatic diseases of endocardium, valve unspecified
0.012 0.988 0.000
I09.0 Rheumatic myocarditis
0.012 0.988 0.000
I27.9 Pulmonary heart disease, unspecified
0.012 0.988 0.000
I71.8 Aortic aneurysm of unspecified site, ruptured
0.012 0.988 0.000
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture
0.012 0.988 0.000
I71.5 Thoracoabdominal aortic aneurysm, ruptured
0.012 0.988 0.000
I71.1 Thoracic aortic aneurysm, ruptured
0.012 0.988 0.000
I27.8 Other specified pulmonary heart diseases
0.012 0.988 0.000
I27.1 Kyphoscoliotic heart disease
0.012 0.988 0.000
I08.8 Other multiple valve diseases
0.012 0.988 0.000
I06.9 Rheumatic aortic valve disease, unspecified
0.011 0.988 0.000
I06.8 Other rheumatic aortic valve diseases
0.011 0.988 0.000
I06.2 Rheumatic aortic stenosis with insufficiency
0.011 0.988 0.000
I06.1 Rheumatic aortic insufficiency
0.011 0.988 0.000
I06.0 Rheumatic aortic stenosis
0.011 0.988 0.000
I77 Other disorders of arteries and arterioles
0.012 0.988 0.000
K50-K52 Noninfective enteritis and colitis
0.000 0.988 0.012
I95.2 Hypotension due to drugs
0.011 0.989 0.000
I12 Hypertensive renal disease
0.011 0.989 0.000
G47.3 Sleep apnoea
0.011 0.989 0.000
I08.0 Disorders of both mitral and aortic valves
0.011 0.989 0.000
I11 Hypertensive heart disease
0.011 0.989 0.000
I13 Hypertensive heart and renal disease
0.011 0.989 0.000
L75 Apocrine sweat disorders
0.000 0.989 0.011
L74 Eccrine sweat disorders
0.000 0.989 0.011
L67 Hair colour and hair shaft abnormalities
0.000 0.989 0.011
L66 Cicatricial alopecia [scarring hair loss]
0.000 0.989 0.011
L64 Androgenic alopecia
0.000 0.989 0.011
L63 Alopecia areata
0.000 0.989 0.011
L62 Nail disorders in diseases classified elsewhere
0.000 0.989 0.011
I01.9 Acute rheumatic heart disease, unspecified
0.011 0.989 0.000
I01.8 Other acute rheumatic heart disease
0.011 0.989 0.000
I01.2 Acute rheumatic myocarditis
0.011 0.989 0.000
I01.1 Acute rheumatic endocarditis
0.011 0.989 0.000
I01.0 Acute rheumatic pericarditis
0.011 0.989 0.000
I02.9 Rheumatic chorea without heart involvement
0.011 0.989 0.000
I02.0 Rheumatic chorea with heart involvement
0.011 0.989 0.000
I79.2 Peripheral angiopathy in diseases classified elsewhere
0.011 0.989 0.000
L73 Other follicular disorders
0.000 0.989 0.011
I77.9 Disorder of arteries and arterioles, unspecified
0.011 0.989 0.000
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.010 0.989 0.000
I15.1 Hypertension secondary to other renal disorders
0.010 0.989 0.000
L70 Acne
0.000 0.990 0.010
I05 Rheumatic mitral valve diseases
0.010 0.990 0.000
I28.9 Disease of pulmonary vessels, unspecified
0.010 0.990 0.000
I28.8 Other specified diseases of pulmonary vessels
0.010 0.990 0.000
I28.1 Aneurysm of pulmonary artery
0.010 0.990 0.000
I28.0 Arteriovenous fistula of pulmonary vessels
0.010 0.990 0.000
L60.8 Other nail disorders
0.000 0.990 0.010
L65.9 Nonscarring hair loss, unspecified
0.000 0.990 0.010
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.010 0.990 0.000
I79.1 Aortitis in diseases classified elsewhere
0.010 0.990 0.000
I79.0 Aneurysm of aorta in diseases classified elsewhere
0.010 0.990 0.000
I70 Atherosclerosis
0.010 0.990 0.000
L68 Hypertrichosis
0.000 0.990 0.010
L60.9 Nail disorder, unspecified
0.000 0.990 0.010
L60.5 Yellow nail syndrome
0.000 0.990 0.010
L60.4 Beau's lines
0.000 0.990 0.010
L60.2 Onychogryphosis
0.000 0.990 0.010
L60.1 Onycholysis
0.000 0.990 0.010
L71 Rosacea
0.000 0.990 0.010
I08.3 Combined disorders of mitral, aortic and tricuspid valves
0.009 0.990 0.000
K51.4 Pseudopolyposis of colon
0.000 0.990 0.010
I78 Diseases of capillaries
0.009 0.991 0.000
I12.9 Hypertensive renal disease without renal failure
0.009 0.991 0.000
K51 Ulcerative colitis
0.000 0.991 0.009
I71.3 Abdominal aortic aneurysm, ruptured
0.009 0.991 0.000
I15.9 Seconday hypertension, unspecified
0.009 0.991 0.000
I15.8 Other secondary hypertension
0.009 0.991 0.000
I15.2 Hypertension secondary to endocrine disorders
0.009 0.991 0.000
I15.0 Renovascular hypertension
0.009 0.991 0.000
L60.3 Nail dystrophy
0.000 0.991 0.009
L65.8 Other specified nonscarring hair loss
0.000 0.991 0.009
L65.2 Alopecia mucinosa
0.000 0.991 0.009
L65.1 Anagen effluvium
0.000 0.991 0.009
L65.0 Telogen effluvium
0.000 0.991 0.009
I72 Other aneurysm
0.009 0.991 0.000
I26 Pulmonary embolism
0.009 0.991 0.000
I11.0 Hypertensive heart disease with (congestive) heart failure
0.009 0.991 0.000
I77.5 Necrosis of artery
0.008 0.991 0.000
I77.4 Coeliac artery compression syndrome
0.008 0.991 0.000
I77.3 Arterial fibromuscular dysplasia
0.008 0.991 0.000
I77.2 Rupture of artery
0.008 0.991 0.000
K51.0 Ulcerative (chronic) enterocolitis
0.000 0.992 0.008
L73.8 Other specified follicular disorders
0.000 0.992 0.008
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.008 0.992 0.000
I13.9 Hypertensive heart and renal disease, unspecified
0.008 0.992 0.000
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure
0.008 0.992 0.000
I13.1 Hypertensive heart and renal disease with renal failure
0.008 0.992 0.000
I13.0 Hypertensive heart and renal disease with (congestive) heart failure
0.008 0.992 0.000
I27.0 Primary pulmonary hypertension
0.008 0.992 0.000
L62.8 Nail disorders in other diseases classified elsewhere
0.000 0.992 0.008
L62.0 Clubbed nail pachydermoperiostosis
0.000 0.992 0.008
L63.9 Alopecia areata, unspecified
0.000 0.992 0.008
L63.8 Other alopecia areata
0.000 0.992 0.008
L63.2 Ophiasis
0.000 0.992 0.008
L63.1 Alopecia universalis
0.000 0.992 0.008
L63.0 Alopecia (capitis) totalis
0.000 0.992 0.008
L64.9 Androgenic alopecia, unspecified
0.000 0.992 0.008
L64.8 Other androgenic alopecia
0.000 0.992 0.008
L64.0 Drug-induced androgenic alopecia
0.000 0.992 0.008
L66.9 Cicatricial alopecia, unspecified
0.000 0.992 0.008
L66.8 Other cicatricial alopecia
0.000 0.992 0.008
L66.4 Folliculitis ulerythematosa reticulata
0.000 0.992 0.008
L66.3 Perifolliculitis capitis abscedens
0.000 0.992 0.008
L66.2 Folliculitis decalvans
0.000 0.992 0.008
L66.1 Lichen planopilaris
0.000 0.992 0.008
L66.0 Pseudopelade
0.000 0.992 0.008
L67.9 Hair colour and hair shaft abnormality, unspecified
0.000 0.992 0.008
L67.8 Other hair colour and hair shaft abnormalities
0.000 0.992 0.008
L67.1 Variations in hair colour
0.000 0.992 0.008
L67.0 Trichorrhexis nodosa
0.000 0.992 0.008
L73.9 Follicular disorder, unspecified
0.000 0.992 0.008
L74.9 Eccrine sweat disorder, unspecified
0.000 0.992 0.008
L74.8 Other eccrine sweat disorders
0.000 0.992 0.008
L74.4 Anhidrosis
0.000 0.992 0.008
L74.3 Miliaria, unspecified
0.000 0.992 0.008
L74.2 Miliaria profunda
0.000 0.992 0.008
L74.1 Miliaria crystallina
0.000 0.992 0.008
L74.0 Miliaria rubra
0.000 0.992 0.008
L75.9 Apocrine sweat disorder, unspecified
0.000 0.992 0.008
L75.8 Other apocrine sweat disorders
0.000 0.992 0.008
L75.2 Apocrine miliaria
0.000 0.992 0.008
L75.1 Chromhidrosis
0.000 0.992 0.008
L75.0 Bromhidrosis
0.000 0.992 0.008
L73.1 Pseudofolliculitis barbae
0.000 0.992 0.008
L73.0 Acne keloid
0.000 0.992 0.008
I05.1 Rheumatic mitral insufficiency
0.008 0.992 0.000
I11.9 Hypertensive heart disease without (congestive) heart failure
0.008 0.992 0.000
I05.8 Other mitral valve diseases
0.007 0.992 0.000
L70.9 Acne, unspecified
0.000 0.992 0.008
L70.8 Other acne
0.000 0.992 0.008
L70.5 Acne excoriee des jeunes filles
0.000 0.992 0.008
L70.4 Infantile acne
0.000 0.992 0.008
L70.3 Acne tropica
0.000 0.992 0.008
L70.2 Acne varioliformis
0.000 0.992 0.008
L70.1 Acne conglobata
0.000 0.992 0.008
L72.1 Trichilemmal cyst
0.000 0.992 0.008
I77.0 Arteriovenous fistula, acquired
0.008 0.992 0.000
I77.6 Arteritis, unspecified
0.008 0.992 0.000
O68.0 Labour and delivery complicated by foetal heart rate anomaly
0.000 0.992 0.008
L70.0 Acne vulgaris
0.000 0.993 0.007
I70.9 Generalised and unspecified atherosclerosis
0.007 0.993 0.000
I70.8 Atherosclerosis of other arteries
0.007 0.993 0.000
I70.1 Atherosclerosis of renal artery
0.007 0.993 0.000
L68.9 Hypertrichosis, unspecified
0.000 0.993 0.007
L68.8 Other hypertrichosis
0.000 0.993 0.007
L68.3 Polytrichia
0.000 0.993 0.007
L68.2 Localised hypertrichosis
0.000 0.993 0.007
L68.1 Acquired hypertrichosis lanuginosa
0.000 0.993 0.007
I77.1 Stricture of artery
0.007 0.993 0.000
L73.2 Hidradenitis suppurativa
0.000 0.993 0.007
L71.8 Other rosacea
0.000 0.993 0.007
L71.1 Rhinophyma
0.000 0.993 0.007
L71.0 Perioral dermatitis
0.000 0.993 0.007
I78.0 Hereditary haemorrhagic telangiectasia
0.007 0.993 0.000
I12.0 Hypertensive renal disease with renal failure
0.007 0.993 0.000
I05.2 Mitral stenosis with insufficiency
0.007 0.993 0.000
I78.8 Other diseases of capillaries
0.007 0.993 0.000
I78.9 Disease of capillaries, unspecified
0.007 0.993 0.000
K51.1 Ulcerative (chronic) ileocolitis
0.000 0.993 0.007
I77.8 Other specified disorders of arteries and arterioles
0.007 0.993 0.000
K51.3 Ulcerative (chronic) rectosigmoiditis
0.000 0.993 0.007
I05.0 Mitral stenosis
0.007 0.993 0.000
I73 Other peripheral vascular diseases
0.006 0.993 0.000
I26.0 Pulmonary embolism with mention of acute cor pulmonale
0.006 0.993 0.000
I72.9 Aneurysm of unspecified site
0.006 0.993 0.000
I72.6 Aneurysm and dissection of vertebral artery
0.006 0.993 0.000
I72.5 Aneurysm and dissection of other precerebral arteries
0.006 0.993 0.000
I72.2 Aneurysm of renal artery
0.006 0.993 0.000
I72.1 Aneurysm of artery of upper extremity
0.006 0.993 0.000
L68.0 Hirsutism
0.000 0.993 0.006
I70.0 Atherosclerosis of aorta
0.006 0.994 0.000
I70.2 Atherosclerosis of arteries of the extremities
0.006 0.994 0.000
I72.8 Aneurysm of other specified arteries
0.006 0.994 0.000
L71.9 Rosacea, unspecified
0.000 0.994 0.006
I72.3 Aneurysm of iliac artery
0.006 0.994 0.000
R93.2 Abnormal findings on diagnostic imaging of liver and biliary tract
0.006 0.994 0.000
I72.0 Aneurysm of carotid artery
0.006 0.994 0.000
K52 Other non-infective gastro-enteritis and colitis
0.000 0.994 0.006
I95.9 Hypotension, unspecified
0.006 0.994 0.000
I70.11 Atherosclerosis of renal artery (with gangrene)
0.005 0.994 0.000
I70.10 Atherosclerosis of renal artery (without gangrene)
0.005 0.994 0.000
I70.81 Atherosclerosis of other arteries (with gangrene)
0.005 0.994 0.000
I70.80 Atherosclerosis of other arteries (without gangrene)
0.005 0.994 0.000
I70.91 Generalized and unspecified atherosclerosis (with gangrene)
0.005 0.994 0.000
I70.90 Generalized and unspecified atherosclerosis (without gangrene)
0.005 0.994 0.000
K51.5 Mucosal proctocolitis
0.000 0.995 0.005
I05.9 Mitral valve disease, unspecified
0.005 0.995 0.001
K51.2 Ulcerative (chronic) proctitis
0.000 0.995 0.005
M75.5 Bursitis of shoulder
0.000 0.995 0.005
I72.4 Aneurysm of artery of lower extremity
0.005 0.995 0.000
I73.8 Other specified peripheral vascular diseases
0.005 0.995 0.000
K51.8 Other ulcerative colitis
0.000 0.995 0.005
I73.1 Thromboangiitis obliterans [Buerger]
0.005 0.995 0.000
K52.3 Indeterminate colitis
0.000 0.995 0.005
I70.01 Atherosclerosis of aorta (with gangrene)
0.004 0.995 0.000
I70.21 Atherosclerosis of arteries of extremities (with gangrene)
0.004 0.995 0.000
K51.9 Ulcerative colitis, unspecified
0.000 0.995 0.005
K52.0 Gastro-enteritis and colitis due to radiation
0.000 0.995 0.005
K70.9 Alcoholic liver disease, unspecified
0.004 0.996 0.000
K52.2 Allergic and dietetic gastro-enteritis and colitis
0.000 0.996 0.004
H25.1 Senile nuclear cataract
0.004 0.996 0.000
G93.3 Postviral fatigue syndrome
0.004 0.996 0.000
G47 Sleep disorders
0.004 0.996 0.000
Z36.3 Antenatal screening for malformations using ultrasound and other physical methods
0.004 0.996 0.000
Z36.0 Antenatal screening for chromosomal anomalies
0.004 0.996 0.000
I70.00 Atherosclerosis of aorta (without gangrene)
0.003 0.996 0.001
L92.9 Granulomatous disorder of skin and subcutaneous tissue, unspecified
0.000 0.996 0.004
G93 Other disorders of brain
0.004 0.996 0.000
I73.9 Peripheral vascular disease, unspecified
0.004 0.996 0.000
G93.2 Benign intracranial hypertension
0.003 0.996 0.000
K52.8 Other specified non-infective gastro-enteritis and colitis
0.000 0.996 0.003
G44.2 Tension-type headache
0.003 0.997 0.000
T42.4 Benzodiazepines
0.000 0.997 0.003
G93.0 Cerebral cysts
0.003 0.997 0.000
I51.8 Other ill-defined heart diseases
0.003 0.997 0.000
T17.2 Foreign body in pharynx
0.000 0.997 0.003
N73.9 Female pelvic inflammatory disease, unspecified
0.000 0.997 0.003
I70.20 Atherosclerosis of arteries of extremities (without gangrene)
0.003 0.997 0.000
G47.1 Disorders of excessive somnolence [hypersomnias]
0.003 0.997 0.000
N73 Other female pelvic inflammatory diseases
0.000 0.997 0.003
R56.8 Other and unspecified convulsions
0.003 0.997 0.000
Z36 Antenatal screening
0.003 0.997 0.000
K70 Alcoholic liver disease
0.003 0.997 0.000
G93.4 Encephalopathy, unspecified
0.003 0.997 0.000
O80.0 Spontaneous vertex delivery
0.000 0.997 0.003
N71 Inflammatory disease of uterus, except cervix
0.000 0.997 0.003
K52.1 Toxic gastro-enteritis and colitis
0.000 0.997 0.003
Z36.2 Other antenatal screening based on amniocentesis
0.003 0.997 0.000
G93.1 Anoxic brain damage, not elsewhere classified
0.003 0.997 0.000
G47.4 Narcolepsy and cataplexy
0.003 0.997 0.000
G47.2 Disorders of the sleep-wake schedule
0.003 0.997 0.000
N73.6 Female pelvic peritoneal adhesions
0.000 0.997 0.003
E10.9 Without complications
0.003 0.997 0.000
G93.6 Cerebral oedema
0.003 0.997 0.000
N71.1 Chronic inflammatory disease of uterus
0.000 0.997 0.003
D69.3 Idiopathic thrombocytopenic purpura
0.003 0.997 0.000
H00.1 Chalazion
0.003 0.997 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.000 0.997 0.003
N71.9 Inflammatory disease of uterus, unspecified
0.000 0.997 0.003
G93.7 Reye's syndrome
0.003 0.997 0.000
G93.5 Compression of brain
0.003 0.997 0.000
I78.1 Naevus, nonneoplastic
0.002 0.997 0.001
K70.4 Alcoholic hepatic failure
0.003 0.997 0.000
G44 Other headache syndromes
0.003 0.997 0.000
N70 Salpingitis and oophoritis
0.000 0.997 0.003
S63.6 Sprain and strain of finger(s)
0.003 0.997 0.000
N77 Vulvovaginal ulceration and inflammation in diseases classified elsewhere
0.000 0.997 0.003
N77.1 Vaginitis, vulvitis and vulvovaginitis in infectious and parasitic diseases classified elsewhere
0.000 0.997 0.003
Z82.4 Family history of ischaemic heart disease and other diseases of the circulatory system
0.003 0.997 0.000
S51.9 Open wound of forearm, part unspecified
0.003 0.997 0.000
G44.0 Cluster headache syndrome
0.003 0.997 0.000
N76 Other inflammation of vagina and vulva
0.000 0.997 0.003
K70.3 Alcoholic cirrhosis of liver
0.003 0.997 0.000
N76.0 Acute vaginitis
0.000 0.997 0.003
D69.6 Thrombocytopenia, unspecified
0.003 0.997 0.000
N70.1 Chronic salpingitis and oophoritis
0.000 0.997 0.003
N73.8 Other specified female pelvic inflammatory diseases
0.000 0.997 0.002
N73.5 Female pelvic peritonitis, unspecified
0.000 0.997 0.002
N73.4 Female chronic pelvic peritonitis
0.000 0.997 0.002
N73.3 Female acute pelvic peritonitis
0.000 0.997 0.002
N73.2 Unspecified parametritis and pelvic cellulitis
0.000 0.997 0.002
N73.1 Chronic parametritis and pelvic cellulitis
0.000 0.997 0.002
N73.0 Acute parametritis and pelvic cellulitis
0.000 0.997 0.002
Z36.9 Antenatal screening, unspecified
0.003 0.997 0.000
G93.8 Other specified disorders of brain
0.003 0.997 0.000
Z36.5 Antenatal screening for isoimmunisation
0.002 0.997 0.000
Z36.1 Antenatal screening for raised alphafetoprotein level
0.002 0.997 0.000
G47.0 Disorders of initiating and maintaining sleep [insomnias]
0.002 0.997 0.000
K70.2 Alcoholic fibrosis and sclerosis of liver
0.002 0.997 0.000
S51 Open wound of forearm
0.002 0.997 0.000
G93.9 Disorder of brain, unspecified
0.002 0.998 0.000
N70.9 Salpingitis and oophoritis, unspecified
0.000 0.998 0.002
N71.0 Acute inflammatory disease of uterus
0.000 0.998 0.002
Z48.0 Attention to surgical dressings and sutures
0.000 0.998 0.002
G47.8 Other sleep disorders
0.002 0.998 0.000
M47.92 Spondylosis, unspecified (Cervical region)
0.002 0.998 0.000
D69 Purpura and other haemorrhagic conditions
0.002 0.998 0.000
K70.1 Alcoholic hepatitis
0.002 0.998 0.000
G44.4 Drug-induced headache, not elsewhere classified
0.002 0.998 0.000
K14.8 Other diseases of tongue
0.000 0.998 0.002
N76.4 Abscess of vulva
0.000 0.998 0.002
Z36.8 Other antenatal screening
0.002 0.998 0.000
N74 Female pelvic inflammatory disorders in diseases classified elsewhere
0.000 0.998 0.002
C80.0 Malignant neoplasm, primary site unknown, so stated
0.002 0.998 0.000
N76.2 Acute vulvitis
0.000 0.998 0.002
S51.0 Open wound of elbow
0.002 0.998 0.000
G44.8 Other specified headache syndromes
0.002 0.998 0.000
G44.3 Chronic posttraumatic headache
0.002 0.998 0.000
G44.1 Vascular headache, not elsewhere classified
0.002 0.998 0.000
N70.0 Acute salpingitis and oophoritis
0.000 0.998 0.002
S51.8 Open wound of other parts of forearm
0.002 0.998 0.000
K70.0 Alcoholic fatty liver
0.002 0.998 0.000
N77.8 Vulvovaginal ulceration and inflammation in other diseases classified elsewhere
0.000 0.998 0.002
N77.0 Ulceration of vulva in infectious and parasitic diseases classified elsewhere
0.000 0.998 0.002
D69.4 Other primary thrombocytopenia
0.002 0.998 0.000
H02.1 Ectropion of eyelid
0.000 0.998 0.002
N76.5 Ulceration of vagina
0.000 0.998 0.002
N76.1 Subacute and chronic vaginitis
0.000 0.998 0.002
K52.9 Non-infective gastro-enteritis and colitis, unspecified
0.000 0.998 0.002
Z36.4 Antenatal screening for foetal growth retardation using ultrasound and other physical methods
0.002 0.998 0.000
M75.1 Rotator cuff syndrome
0.000 0.998 0.002
N76.6 Ulceration of vulva
0.000 0.998 0.002
G47.9 Sleep disorder, unspecified
0.002 0.998 0.000
N76.8 Other specified inflammation of vagina and vulva
0.000 0.998 0.002
S51.7 Multiple open wounds of forearm
0.002 0.998 0.000
N75 Diseases of Bartholin's gland
0.000 0.998 0.002
N76.3 Subacute and chronic vulvitis
0.000 0.998 0.002
M81.99 Osteoporosis, unspecified (Site unspecified)
0.000 0.998 0.002
D69.9 Haemorrhagic condition, unspecified
0.002 0.998 0.000
D69.8 Other specified haemorrhagic conditions
0.002 0.998 0.000
D69.2 Other nonthrombocytopenic purpura
0.002 0.998 0.000
D69.1 Qualitative platelet defects
0.002 0.998 0.000
D69.0 Allergic purpura
0.002 0.998 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.000 0.998 0.002
J93.9 Pneumothorax, unspecified
0.002 0.998 0.000
N74.8 Female pelvic inflammatory disorders in other diseases classified elsewhere
0.000 0.998 0.002
N74.4 Female chlamydial pelvic inflammatory disease
0.000 0.998 0.002
N74.3 Female gonococcal pelvic inflammatory disease
0.000 0.998 0.002
N74.2 Female syphilitic pelvic inflammatory disease
0.000 0.998 0.002
N74.1 Female tuberculous pelvic inflammatory disease
0.000 0.998 0.002
N74.0 Tuberculous infection of cervix uteri
0.000 0.998 0.002
M47.90 Spondylosis, unspecified (Multiple sites in spine)
0.002 0.998 0.000
H00.0 Hordeolum and other deep inflammation of eyelid
0.002 0.998 0.000
D09.0 Bladder
0.000 0.998 0.002
E10 Insulin-dependent diabetes mellitus
0.002 0.998 0.000
G90.2 Horner's syndrome
0.002 0.998 0.000
H00 Hordeolum and chalazion
0.002 0.998 0.000
E10.5 With peripheral circulatory complications
0.002 0.998 0.000
M47.9 Spondylosis, unspecified
0.002 0.998 0.000
N94.6 Dysmenorrhoea, unspecified
0.000 0.998 0.002
E10.3 With ophthalmic complications
0.002 0.998 0.000
G63.2 Diabetic polyneuropathy
0.002 0.998 0.000
K85.1 Biliary acute pancreatitis
0.002 0.998 0.000
C43.9 Malignant melanoma of skin, unspecified
0.000 0.998 0.002
D69.5 Secondary thrombocytopenia
0.002 0.998 0.000
H25.8 Other senile cataract
0.002 0.998 0.000
Z51.4 Preparatory care for treatment, not elsewhere classified
0.000 0.998 0.002
M47.99 Spondylosis, unspecified (Site unspecified)
0.002 0.998 0.000
N75.9 Disease of Bartholin's gland, unspecified
0.000 0.998 0.002
N75.8 Other diseases of Bartholin's gland
0.000 0.998 0.002
G90 Disorders of autonomic nervous system
0.002 0.998 0.000
L92 Granulomatous disorders of skin and subcutaneous tissue
0.000 0.998 0.002
S50-S59 Injuries to the elbow and forearm
0.002 0.998 0.000
S50.8 Other superficial injuries of forearm
0.002 0.998 0.000
H25 Senile cataract
0.002 0.998 0.000
N75.1 Abscess of Bartholin's gland
0.000 0.998 0.002
T17 Foreign body in respiratory tract
0.000 0.998 0.002
E10.4 With neurological complications
0.002 0.998 0.000
S92.00 Fracture of calcaneus (closed)
0.002 0.998 0.000
R30.0 Dysuria
0.000 0.998 0.002
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants
0.000 0.998 0.002
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified
0.000 0.998 0.002
T42.5 Mixed antiepileptics, not elsewhere classified
0.000 0.998 0.002
T42.3 Barbiturates
0.000 0.998 0.002
T42.2 Succinimides and oxazolidinediones
0.000 0.998 0.002
T42.1 Iminostilbenes
0.000 0.998 0.002
T42.0 Hydantoin derivatives
0.000 0.998 0.002
S53 Dislocation, sprain and strain of joints and ligaments of elbow
0.002 0.998 0.000
S50 Superficial injury of forearm
0.002 0.998 0.000
E10.8 With unspecified complications
0.002 0.998 0.000
E10.7 With multiple complications
0.002 0.998 0.000
E10.6 With other specified complications
0.002 0.998 0.000
E10.0 With coma
0.002 0.998 0.000
K66.0 Peritoneal adhesions
0.002 0.998 0.000
S53.3 Traumatic rupture of ulnar collateral ligament
0.002 0.998 0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.000 0.998 0.002
S56 Injury of muscle and tendon at forearm level
0.002 0.998 0.000
M47.97 Spondylosis, unspecified (Lumbosacral region)
0.002 0.998 0.000
T17.9 Foreign body in respiratory tract, part unspecified
0.000 0.998 0.002
H02.0 Entropion and trichiasis of eyelid
0.000 0.998 0.002
K75.0 Abscess of liver
0.002 0.998 0.000
O82.0 Delivery by elective Caesarean section
0.002 0.998 0.000
M47.98 Spondylosis, unspecified (Sacral and sacrococcygeal region)
0.001 0.998 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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