TreeWAS – Variant ID: rs4936099

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
I71.4 Abdominal aortic aneurysm, without mention of rupture	0.951	0.049	0.000
I71 Aortic aneurysm and dissection	0.891	0.109	0.000
I71.2 Thoracic aortic aneurysm, without mention of rupture	0.856	0.144	0.000
I71.9 Aortic aneurysm of unspecified site, without mention of rupture	0.765	0.235	0.000
I71.1 Thoracic aortic aneurysm, ruptured	0.759	0.241	0.000
I71.8 Aortic aneurysm of unspecified site, ruptured	0.639	0.361	0.000
I71.5 Thoracoabdominal aortic aneurysm, ruptured	0.639	0.361	0.000
I71.3 Abdominal aortic aneurysm, ruptured	0.623	0.377	0.000
I71.0 Dissection of aorta [any part]	0.617	0.383	0.000
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture	0.587	0.412	0.000
M79.86 Other specified soft tissue disorders (Lower leg)	0.032	0.968	0.000
I70-I79 Diseases of arteries, arterioles and capillaries	0.031	0.969	0.000
I72 Other aneurysm	0.023	0.977	0.000
I74 Arterial embolism and thrombosis	0.023	0.977	0.000
I72.2 Aneurysm of renal artery	0.021	0.979	0.000
I77 Other disorders of arteries and arterioles	0.020	0.980	0.000
I72.1 Aneurysm of artery of upper extremity	0.019	0.980	0.000
I74.4 Embolism and thrombosis of arteries of extremities, unspecified	0.019	0.981	0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.019	0.981	0.000
I77.0 Arteriovenous fistula, acquired	0.019	0.981	0.000
I74.1 Embolism and thrombosis of other and unspecified parts of aorta	0.018	0.982	0.000
I74.8 Embolism and thrombosis of other arteries	0.018	0.982	0.000
I74.2 Embolism and thrombosis of arteries of the upper extremities	0.018	0.982	0.000
I72.6 Aneurysm and dissection of vertebral artery	0.017	0.983	0.000
I72.5 Aneurysm and dissection of other precerebral arteries	0.017	0.983	0.000
I77.2 Rupture of artery	0.016	0.984	0.000
I72.3 Aneurysm of iliac artery	0.016	0.984	0.000
I72.9 Aneurysm of unspecified site	0.016	0.984	0.000
I74.0 Embolism and thrombosis of abdominal aorta	0.016	0.984	0.000
I72.8 Aneurysm of other specified arteries	0.016	0.984	0.000
I74.9 Embolism and thrombosis of unspecified artery	0.015	0.984	0.000
I77.8 Other specified disorders of arteries and arterioles	0.015	0.984	0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities	0.015	0.985	0.000
I77.5 Necrosis of artery	0.015	0.985	0.000
I77.4 Coeliac artery compression syndrome	0.015	0.985	0.000
H71 Cholesteatoma of middle ear	0.015	0.985	0.000
I77.9 Disorder of arteries and arterioles, unspecified	0.014	0.986	0.000
I74.5 Embolism and thrombosis of iliac artery	0.014	0.986	0.000
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.014	0.986	0.000
I77.3 Arterial fibromuscular dysplasia	0.014	0.986	0.000
I79.1 Aortitis in diseases classified elsewhere	0.013	0.986	0.000
I79.0 Aneurysm of aorta in diseases classified elsewhere	0.013	0.986	0.000
J93.9 Pneumothorax, unspecified	0.014	0.986	0.000
I72.4 Aneurysm of artery of lower extremity	0.013	0.987	0.000
R47.8 Other and unspecified speech disturbances	0.000	0.987	0.013
I72.0 Aneurysm of carotid artery	0.013	0.987	0.000
I78 Diseases of capillaries	0.012	0.988	0.000
I70 Atherosclerosis	0.011	0.989	0.000
H74.4 Polyp of middle ear	0.010	0.990	0.000
H74 Other disorders of middle ear and mastoid	0.010	0.990	0.000
H65-H75 Diseases of middle ear and mastoid	0.010	0.990	0.000
O02.1 Missed abortion	0.000	0.991	0.009
I78.9 Disease of capillaries, unspecified	0.009	0.991	0.000
H70 Mastoiditis and related conditions	0.009	0.991	0.000
Q23.1 Congenital insufficiency of aortic valve	0.009	0.991	0.000
I77.6 Arteritis, unspecified	0.009	0.991	0.000
I78.8 Other diseases of capillaries	0.008	0.991	0.000
I79.2 Peripheral angiopathy in diseases classified elsewhere	0.008	0.991	0.000
H74.9 Disorder of middle ear and mastoid, unspecified	0.008	0.992	0.000
H70.9 Mastoiditis, unspecified	0.008	0.992	0.000
H73 Other disorders of tympanic membrane	0.008	0.992	0.000
Q23 Congenital malformations of aortic and mitral valves	0.008	0.992	0.000
I70.8 Atherosclerosis of other arteries	0.007	0.992	0.000
I70.9 Generalised and unspecified atherosclerosis	0.007	0.992	0.000
H74.2 Discontinuity and dislocation of ear ossicles	0.008	0.992	0.000
I73 Other peripheral vascular diseases	0.008	0.992	0.000
H74.3 Other acquired abnormalities of ear ossicles	0.008	0.992	0.000
I77.1 Stricture of artery	0.008	0.992	0.000
R90.0 Intracranial space-occupying lesion	0.008	0.992	0.000
I70.1 Atherosclerosis of renal artery	0.007	0.993	0.000
H68 Eustachian salpingitis and obstruction	0.007	0.993	0.000
H69 Other disorders of Eustachian tube	0.007	0.993	0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere	0.007	0.993	0.000
H67 Otitis media in diseases classified elsewhere	0.007	0.993	0.000
J93 Pneumothorax	0.007	0.993	0.000
R47.1 Dysarthria and anarthria	0.000	0.993	0.007
I70.0 Atherosclerosis of aorta	0.007	0.993	0.000
Q20-Q28 Congenital malformations of the circulatory system	0.007	0.993	0.000
H70.8 Other mastoiditis and related conditions	0.007	0.993	0.000
R47 Speech disturbances, not elsewhere classified	0.000	0.993	0.007
H70.1 Chronic mastoiditis	0.007	0.993	0.000
Q24 Other congenital malformations of heart	0.007	0.993	0.000
Q23.3 Congenital mitral insufficiency	0.007	0.993	0.000
H72 Perforation of tympanic membrane	0.007	0.993	0.000
H70.2 Petrositis	0.007	0.993	0.000
H69.9 Eustachian tube disorder, unspecified	0.007	0.993	0.000
H73.1 Chronic myringitis	0.007	0.993	0.000
Q21 Congenital malformations of cardiac septa	0.007	0.993	0.000
H74.1 Adhesive middle ear disease	0.006	0.993	0.000
Q27 Other congenital malformations of peripheral vascular system	0.007	0.993	0.000
H72.8 Other perforations of tympanic membrane	0.006	0.994	0.000
H70.0 Acute mastoiditis	0.006	0.994	0.000
H73.9 Disorder of tympanic membrane, unspecified	0.006	0.994	0.000
H74.0 Tympanosclerosis	0.006	0.994	0.000
Q21.1 Atrial septal defect	0.006	0.994	0.000
Q24.0 Dextrocardia	0.006	0.994	0.000
I73.8 Other specified peripheral vascular diseases	0.006	0.994	0.000
H73.8 Other specified disorders of tympanic membrane	0.006	0.994	0.000
J93.0 Spontaneous tension pneumothorax	0.006	0.994	0.000
Q24.6 Congenital heart block	0.006	0.994	0.000
J98.8 Other specified respiratory disorders	0.006	0.994	0.000
Q23.9 Congenital malformation of aortic and mitral valves, unspecified	0.006	0.994	0.000
Q23.8 Other congenital malformations of aortic and mitral valves	0.006	0.994	0.000
Q23.4 Hypoplastic left heart syndrome	0.006	0.994	0.000
Q23.2 Congenital mitral stenosis	0.006	0.994	0.000
Q24.5 Malformation of coronary vessels	0.006	0.994	0.000
H72.1 Attic perforation of tympanic membrane	0.006	0.994	0.000
H73.0 Acute myringitis	0.006	0.994	0.000
I70.81 Atherosclerosis of other arteries (with gangrene)	0.006	0.994	0.000
Q24.4 Congenital subaortic stenosis	0.006	0.994	0.000
I70.91 Generalized and unspecified atherosclerosis (with gangrene)	0.005	0.994	0.000
F31.9 Bipolar affective disorder, unspecified	0.000	0.994	0.006
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms	0.000	0.994	0.006
H68.1 Obstruction of Eustachian tube	0.005	0.994	0.000
I70.11 Atherosclerosis of renal artery (with gangrene)	0.005	0.994	0.000
Q27.8 Other specified congenital malformations of peripheral vascular system	0.006	0.994	0.000
H72.2 Other marginal perforations of tympanic membrane	0.006	0.994	0.000
F31 Bipolar affective disorder	0.000	0.994	0.006
H68.0 Eustachian salpingitis	0.005	0.994	0.000
H74.8 Other specified disorders of middle ear and mastoid	0.005	0.994	0.000
H69.0 Patulous Eustachian tube	0.005	0.994	0.000
H67.8 Otitis media in other diseases classified elsewhere	0.005	0.995	0.000
H67.1 Otitis media in viral diseases classified elsewhere	0.005	0.995	0.000
H67.0 Otitis media in bacterial diseases classified elsewhere	0.005	0.995	0.000
H75.8 Other specified disorders of middle ear and mastoid in diseases classified elsewhere	0.005	0.995	0.000
H75.0 Mastoiditis in infectious and parasitic diseases classified elsewhere	0.005	0.995	0.000
Q27.3 Peripheral arteriovenous malformation	0.005	0.995	0.000
J93.8 Other pneumothorax	0.005	0.995	0.000
I70.01 Atherosclerosis of aorta (with gangrene)	0.005	0.995	0.000
Q26 Congenital malformations of great veins	0.005	0.995	0.000
Q20 Congenital malformations of cardiac chambers and connexions	0.005	0.995	0.000
Q21.0 Ventricular septal defect	0.005	0.995	0.000
Q24.9 Congenital malformation of the heart, unspecified	0.005	0.995	0.000
I70.80 Atherosclerosis of other arteries (without gangrene)	0.005	0.995	0.000
Q24.3 Pulmonary infundibular stenosis	0.005	0.995	0.000
Q24.2 Cor triatriatum	0.005	0.995	0.000
Q24.1 Levocardia	0.005	0.995	0.000
Y83.9 Surgical procedure, unspecified	0.005	0.995	0.000
Q27.9 Congenital malformation of peripheral vascular system, unspecified	0.005	0.995	0.000
I70.90 Generalized and unspecified atherosclerosis (without gangrene)	0.005	0.995	0.000
I78.0 Hereditary haemorrhagic telangiectasia	0.005	0.995	0.000
Q23.0 Congenital stenosis of aortic valve	0.005	0.995	0.000
Q21.4 Aortopulmonary septal defect	0.005	0.995	0.000
Q21.2 Atrioventricular septal defect	0.005	0.995	0.000
H66 Suppurative and unspecified otitis media	0.005	0.995	0.000
Q21.9 Congenital malformation of cardiac septum, unspecified	0.005	0.995	0.000
I70.2 Atherosclerosis of arteries of the extremities	0.005	0.995	0.000
Q27.4 Congenital phlebectasia	0.005	0.995	0.000
Q27.2 Other congenital malformations of renal artery	0.005	0.995	0.000
Q27.1 Congenital renal artery stenosis	0.005	0.995	0.000
Q27.0 Congenital absence and hypoplasia of umbilical artery	0.005	0.995	0.000
Q21.3 Tetralogy of Fallot	0.005	0.995	0.000
Q28 Other congenital malformations of circulatory system	0.005	0.995	0.000
Q25 Congenital malformations of great arteries	0.005	0.995	0.000
G55.2 Nerve root and plexus compressions in spondylosis	0.005	0.995	0.000
I73.1 Thromboangiitis obliterans [Buerger]	0.005	0.995	0.000
F31.0 Bipolar affective disorder, current episode hypomanic	0.000	0.995	0.005
I70.10 Atherosclerosis of renal artery (without gangrene)	0.004	0.995	0.000
J98.9 Respiratory disorder, unspecified	0.005	0.995	0.000
M47.80 Other spondylosis (Multiple sites in spine)	0.000	0.995	0.005
Q22 Congenital malformations of pulmonary and tricuspid valves	0.005	0.995	0.000
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms	0.000	0.995	0.005
Q21.8 Other congenital malformations of cardiac septa	0.005	0.995	0.000
I78.1 Naevus, nonneoplastic	0.005	0.995	0.000
F31.7 Bipolar affective disorder, currently in remission	0.000	0.995	0.004
F31.8 Other bipolar affective disorders	0.000	0.996	0.004
F31.3 Bipolar affective disorder, current episode mild or moderate depression	0.000	0.996	0.004
Q25.6 Stenosis of pulmonary artery	0.004	0.996	0.000
Q24.8 Other specified congenital malformations of heart	0.004	0.996	0.000
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms	0.000	0.996	0.004
J93.1 Other spontaneous pneumothorax	0.004	0.996	0.000
R25.8 Other and unspecified abnormal involuntary movements	0.000	0.996	0.004
F31.6 Bipolar affective disorder, current episode mixed	0.000	0.996	0.004
J98 Other respiratory disorders	0.004	0.996	0.000
H66.4 Suppurative otitis media, unspecified	0.004	0.996	0.000
I70.00 Atherosclerosis of aorta (without gangrene)	0.004	0.996	0.000
H66.2 Chronic atticoantral suppurative otitis media	0.004	0.996	0.000
J94.8 Other specified pleural conditions	0.004	0.996	0.000
Q20.9 Congenital malformation of cardiac chambers and connexions, unspecified	0.004	0.996	0.000
Q20.8 Other congenital malformations of cardiac chambers and connexions	0.004	0.996	0.000
Q20.6 Isomerism of atrial appendages	0.004	0.996	0.000
Q20.5 Discordant atrioventricular connexion	0.004	0.996	0.000
Q20.4 Double inlet ventricle	0.004	0.996	0.000
Q20.3 Discordant ventriculoarterial connexion	0.004	0.996	0.000
Q20.2 Double outlet left ventricle	0.004	0.996	0.000
Q20.1 Double outlet right ventricle	0.004	0.996	0.000
Q20.0 Common arterial trunk	0.004	0.996	0.000
Q26.9 Congenital malformation of great vein, unspecified	0.004	0.996	0.000
Q26.8 Other congenital malformations of great veins	0.004	0.996	0.000
Q26.6 Portal vein-hepatic artery fistula	0.004	0.996	0.000
Q26.5 Anomalous portal venous connexion	0.004	0.996	0.000
Q26.4 Anomalous pulmonary venous connexion, unspecified	0.004	0.996	0.000
Q26.3 Partial anomalous pulmonary venous connexion	0.004	0.996	0.000
Q26.2 Total anomalous pulmonary venous connexion	0.004	0.996	0.000
Q26.1 Persistent left superior vena cava	0.004	0.996	0.000
Q26.0 Congenital stenosis of vena cava	0.004	0.996	0.000
Q28.3 Other malformations of cerebral vessels	0.004	0.996	0.000
H92.1 Otorrhoea	0.004	0.996	0.000
H66.3 Other chronic suppurative otitis media	0.004	0.996	0.000
Q28.0 Arteriovenous malformation of precerebral vessels	0.004	0.996	0.000
J98.5 Diseases of mediastinum, not elsewhere classified	0.004	0.996	0.000
Q25.9 Congenital malformation of great arteries, unspecified	0.004	0.996	0.000
Q25.8 Other congenital malformations of great arteries	0.004	0.996	0.000
Q25.5 Atresia of pulmonary artery	0.004	0.996	0.000
Q25.2 Atresia of aorta	0.004	0.996	0.000
Q28.9 Congenital malformation of circulatory system, unspecified	0.004	0.996	0.000
Q28.8 Other specified congenital malformations of circulatory system	0.004	0.996	0.000
Q28.1 Other malformations of precerebral vessels	0.004	0.996	0.000
Q25.0 Patent ductus arteriosus	0.004	0.996	0.000
J98.4 Other disorders of lung	0.004	0.996	0.000
Q22.9 Congenital malformation of tricuspid valve, unspecified	0.003	0.996	0.000
Q22.8 Other congenital malformations of tricuspid valve	0.003	0.996	0.000
Q22.6 Hypoplastic right heart syndrome	0.003	0.996	0.000
Q22.4 Congenital tricuspid stenosis	0.003	0.996	0.000
Q22.3 Other congenital malformations of pulmonary valve	0.003	0.996	0.000
Q22.2 Congenital pulmonary valve insufficiency	0.003	0.996	0.000
Q22.0 Pulmonary valve atresia	0.003	0.996	0.000
O02 Other abnormal products of conception	0.000	0.996	0.004
Q25.4 Other congenital malformations of aorta	0.003	0.996	0.000
Q25.7 Other congenital malformations of pulmonary artery	0.003	0.996	0.000
M87.95 Osteonecrosis, unspecified (Pelvic region and thigh)	0.004	0.996	0.000
H81.0 Meniere's disease	0.004	0.996	0.000
J98.6 Disorders of diaphragm	0.004	0.996	0.000
H66.0 Acute suppurative otitis media	0.003	0.996	0.000
J94 Other pleural conditions	0.004	0.996	0.000
M85.80 Other specified disorders of bone density and structure (Multiple sites)	0.003	0.996	0.000
Q22.5 Ebstein's anomaly	0.003	0.996	0.000
Q25.3 Stenosis of aorta	0.003	0.997	0.000
J94.9 Pleural condition, unspecified	0.003	0.997	0.000
H66.1 Chronic tubotympanic suppurative otitis media	0.003	0.997	0.000
I70.21 Atherosclerosis of arteries of extremities (with gangrene)	0.003	0.997	0.000
C21.0 Anus, unspecified	0.003	0.997	0.000
J98.3 Compensatory emphysema	0.003	0.997	0.000
Q22.1 Congenital pulmonary valve stenosis	0.003	0.997	0.000
Q25.1 Coarctation of aorta	0.003	0.997	0.000
H69.8 Other specified disorders of Eustachian tube	0.002	0.997	0.001
H72.0 Central perforation of tympanic membrane	0.003	0.997	0.000
I73.0 Raynaud's syndrome	0.003	0.997	0.000
F30.9 Manic episode, unspecified	0.000	0.997	0.003
M85.8 Other specified disorders of bone density and structure	0.003	0.997	0.000
M79.89 Other specified soft tissue disorders (Site unspecified)	0.003	0.997	0.000
M79.8 Other specified soft tissue disorders	0.003	0.997	0.000
O02.8 Other specified abnormal products of conception	0.000	0.997	0.003
Z50.1 Other physical therapy	0.003	0.997	0.000
M87.96 Osteonecrosis, unspecified (Lower leg)	0.003	0.997	0.000
I80.8 Phlebitis and thrombophlebitis of other sites	0.003	0.997	0.000
C18.4 Transverse colon	0.000	0.997	0.003
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms	0.000	0.997	0.003
O02.0 Blighted ovum and nonhydatidiform mole	0.000	0.997	0.003
J94.1 Fibrothorax	0.003	0.997	0.000
J94.0 Chylous effusion	0.003	0.997	0.000
M87.9 Osteonecrosis, unspecified	0.003	0.997	0.000
M85.87 Other specified disorders of bone density and structure (Ankle and foot)	0.003	0.997	0.000
I65.2 Occlusion and stenosis of carotid artery	0.000	0.997	0.003
Q28.2 Arteriovenous malformation of cerebral vessels	0.003	0.997	0.000
M85.89 Other specified disorders of bone density and structure (Site unspecified)	0.003	0.997	0.000
J94.2 Haemothorax	0.003	0.997	0.000
J98.2 Interstitial emphysema	0.003	0.997	0.000
O02.9 Abnormal product of conception, unspecified	0.000	0.997	0.003
I31.3 Pericardial effusion (noninflammatory)	0.003	0.997	0.000
M79.81 Other specified soft tissue disorders (Shoulder region)	0.003	0.997	0.000
M85.86 Other specified disorders of bone density and structure (Lower leg)	0.002	0.997	0.000
M85.85 Other specified disorders of bone density and structure (Pelvic region and thigh)	0.002	0.997	0.000
F30 Manic episode	0.000	0.997	0.003
M85.83 Other specified disorders of bone density and structure (Forearm)	0.002	0.998	0.000
F30.2 Mania with psychotic symptoms	0.000	0.998	0.002
M85.84 Other specified disorders of bone density and structure (Hand)	0.002	0.998	0.000
M85.82 Other specified disorders of bone density and structure (Upper arm)	0.002	0.998	0.000
I80.3 Phlebitis and thrombophlebitis of lower extremities, unspecified	0.002	0.998	0.000
S80.8 Other superficial injuries of lower leg	0.002	0.998	0.000
M85.81 Other specified disorders of bone density and structure (Shoulder region)	0.002	0.998	0.000
D41.4 Bladder	0.000	0.998	0.002
M85.88 Other specified disorders of bone density and structure (Other)	0.002	0.998	0.000
J90-J94 Other diseases of pleura	0.002	0.998	0.000
M87.98 Osteonecrosis, unspecified (Other)	0.002	0.998	0.000
M87.91 Osteonecrosis, unspecified (Shoulder region)	0.002	0.998	0.000
M87.99 Osteonecrosis, unspecified (Site unspecified)	0.002	0.998	0.000
M87.94 Osteonecrosis, unspecified (Hand)	0.002	0.998	0.000
M87.93 Osteonecrosis, unspecified (Forearm)	0.002	0.998	0.000
M87.92 Osteonecrosis, unspecified (Upper arm)	0.002	0.998	0.000
M87.90 Osteonecrosis, unspecified (Multiple sites)	0.002	0.998	0.000
H35.3 Degeneration of macula and posterior pole	0.000	0.998	0.002
M79.80 Other specified soft tissue disorders (Multiple sites)	0.002	0.998	0.000
C18.3 Hepatic flexure	0.000	0.998	0.002
H92 Otalgia and effusion of ear	0.002	0.998	0.000
I80.1 Phlebitis and thrombophlebitis of femoral vein	0.002	0.998	0.000
E27.1 Primary adrenocortical insufficiency	0.000	0.998	0.002
M79.82 Other specified soft tissue disorders (Upper arm)	0.002	0.998	0.000
S80.0 Contusion of knee	0.002	0.998	0.000
C18.9 Colon, unspecified	0.000	0.998	0.002
H49.2 Sixth [abducent] nerve palsy	0.000	0.998	0.002
M25.78 Osteophyte (Other)	0.000	0.998	0.002
H72.9 Perforation of tympanic membrane, unspecified	0.002	0.998	0.000
S80 Superficial injury of lower leg	0.002	0.998	0.000
F30.8 Other manic episodes	0.000	0.998	0.002
O86.2 Urinary tract infection following delivery	0.002	0.998	0.000
S80.7 Multiple superficial injuries of lower leg	0.002	0.998	0.000
F30-F39 Mood [affective] disorders	0.000	0.998	0.002
J98.1 Pulmonary collapse	0.002	0.998	0.000
M81.49 Drug-induced osteoporosis (Site unspecified)	0.002	0.998	0.000
R47-R49 Symptoms and signs involving speech and voice	0.000	0.998	0.002
H02.0 Entropion and trichiasis of eyelid	0.000	0.998	0.002
M79.83 Other specified soft tissue disorders (Forearm)	0.002	0.998	0.000
F30.1 Mania without psychotic symptoms	0.000	0.998	0.002
F41.0 Panic disorder [episodic paroxysmal anxiety]	0.000	0.998	0.002
I65.1 Occlusion and stenosis of basilar artery	0.000	0.998	0.002
M87.97 Osteonecrosis, unspecified (Ankle and foot)	0.002	0.998	0.000
M79.88 Other specified soft tissue disorders (Other)	0.002	0.998	0.000
S86.8 Injury of other muscles and tendons at lower leg level	0.002	0.998	0.000
S89.9 Unspecified injury of lower leg	0.002	0.998	0.000
F33.3 Recurrent depressive disorder, current episode severe with psychotic symptoms	0.000	0.998	0.002
F33.8 Other recurrent depressive disorders	0.000	0.998	0.002
K59.3 Megacolon, not elsewhere classified	0.000	0.998	0.002
C18.2 Ascending colon	0.000	0.998	0.002
C18 Malignant neoplasm of colon	0.000	0.998	0.002
F33 Recurrent depressive disorder	0.000	0.998	0.002
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction	0.000	0.998	0.002
I65.0 Occlusion and stenosis of vertebral artery	0.000	0.998	0.002
C18.7 Sigmoid colon	0.000	0.998	0.002
F30.0 Hypomania	0.000	0.998	0.002
S82.50 Fracture of medial malleolus (closed)	0.000	0.998	0.002
S80.1 Contusion of other and unspecified parts of lower leg	0.002	0.998	0.000
R48 Dyslexia and other symbolic dysfunctions, not elsewhere classified	0.000	0.998	0.002
J91 Pleural effusion in conditions classified elsewhere	0.002	0.998	0.000
F33.9 Recurrent depressive disorder, unspecified	0.000	0.998	0.002
Chapter VIII Diseases of the ear and mastoid process	0.002	0.998	0.000
S82.60 Fracture of lateral malleolus (closed)	0.000	0.998	0.002
N89.5 Stricture and atresia of vagina	0.002	0.998	0.000
M54.94 Dorsalgia, unspecified (Thoracic region)	0.002	0.998	0.000
M62.86 Other specified disorders of muscle (Lower leg)	0.000	0.998	0.002
H92.2 Otorrhagia	0.002	0.998	0.000
Z50.0 Cardiac rehabilitation	0.002	0.998	0.000
Z96.8 Presence of other specified functional implants	0.000	0.998	0.002
I80 Phlebitis and thrombophlebitis	0.002	0.998	0.000
N83.8 Other noninflammatory disorders of ovary, Fallopian tube and broad ligament	0.000	0.998	0.002
Z35.0 Supervision of pregnancy with history of infertility	0.000	0.998	0.002
R90 Abnormal findings on diagnostic imaging of central nervous system	0.002	0.998	0.000
C41.0 Bones of skull and face	0.000	0.998	0.002
J98.0 Diseases of bronchus, not elsewhere classified	0.002	0.998	0.000
J99.8 Respiratory disorders in other diseases classified elsewhere	0.002	0.998	0.000
K59.4 Anal spasm	0.000	0.998	0.002
S62.30 Fracture of other metacarpal bone (closed)	0.000	0.998	0.002
H92.0 Otalgia	0.002	0.998	0.000
M79.85 Other specified soft tissue disorders (Pelvic region and thigh)	0.002	0.998	0.000
D68.3 Haemorrhagic disorder due to circulating anticoagulants	0.000	0.998	0.002
T87.6 Other and unspecified complications of amputation stump	0.000	0.998	0.002
F33.4 Recurrent depressive disorder, currently in remission	0.000	0.998	0.001
F38 Other mood [affective] disorders	0.000	0.998	0.001
F34 Persistent mood [affective] disorders	0.000	0.998	0.002
I65.9 Occlusion and stenosis of unspecified precerebral artery	0.000	0.998	0.001
R48.0 Dyslexia and alexia	0.000	0.998	0.001
I70.20 Atherosclerosis of arteries of extremities (without gangrene)	0.001	0.998	0.000
I65.8 Occlusion and stenosis of other precerebral artery	0.000	0.998	0.001
R48.2 Apraxia	0.000	0.998	0.001
R48.1 Agnosia	0.000	0.998	0.001
O86.0 Infection of obstetric surgical wound	0.002	0.998	0.000
R48.8 Other and unspecified symbolic dysfunctions	0.000	0.998	0.001
J99 Respiratory disorders in diseases classified elsewhere	0.002	0.998	0.000
Z50.7 Occupational therapy and vocational rehabilitation, not elsewhere classified	0.002	0.998	0.000
G97.1 Other reaction to spinal and lumbar puncture	0.000	0.998	0.001
I65.3 Occlusion and stenosis of multiple and bilateral precerebral arteries	0.000	0.998	0.001
K73.2 Chronic active hepatitis, not elsewhere classified	0.000	0.998	0.001
M87.86 Other osteonecrosis (Lower leg)	0.001	0.998	0.000
M87.8 Other osteonecrosis	0.001	0.998	0.000
T87.4 Infection of amputation stump	0.000	0.998	0.001
F39 Unspecified mood [affective] disorder	0.000	0.998	0.001
M87 Osteonecrosis	0.001	0.998	0.000
D41.0 Kidney	0.000	0.999	0.001
F34.0 Cyclothymia	0.000	0.999	0.001
J95-J99 Other diseases of the respiratory system	0.001	0.999	0.000
F33.0 Recurrent depressive disorder, current episode mild	0.000	0.999	0.001
S40.9 Superficial injury of shoulder and upper arm, unspecified	0.001	0.999	0.000
M79.84 Other specified soft tissue disorders (Hand)	0.001	0.999	0.000
F33.1 Recurrent depressive disorder, current episode moderate	0.000	0.999	0.001
O86 Other puerperal infections	0.001	0.999	0.000
R17 Unspecified jaundice	0.000	0.999	0.001
M79.87 Other specified soft tissue disorders (Ankle and foot)	0.001	0.999	0.000
C18.5 Splenic flexure	0.000	0.999	0.001
F34.9 Persistent mood [affective] disorder, unspecified	0.000	0.999	0.001
F34.8 Other persistent mood [affective] disorders	0.000	0.999	0.001
F38.1 Other recurrent mood [affective] disorders	0.000	0.999	0.001
K59.8 Other specified functional intestinal disorders	0.000	0.999	0.001
S80.9 Superficial injury of lower leg, unspecified	0.001	0.999	0.000
F38.0 Other single mood [affective] disorders	0.000	0.999	0.001
T87.5 Necrosis of amputation stump	0.000	0.999	0.001
S86 Injury of muscle and tendon at lower leg level	0.001	0.999	0.000
J95.0 Tracheostomy malfunction	0.000	0.999	0.001
Z31.2 In vitro fertilisation	0.000	0.999	0.001
Z50.3 Drug rehabilitation	0.001	0.999	0.000
Z50 Care involving use of rehabilitation procedures	0.001	0.999	0.000
I31.9 Disease of pericardium, unspecified	0.001	0.999	0.000
M87.3 Other secondary osteonecrosis	0.001	0.999	0.000
B44.1 Other pulmonary aspergillosis	0.001	0.999	0.000
E27.2 Addisonian crisis	0.000	0.999	0.001
J99.1 Respiratory disorders in other diffuse connective tissue disorders	0.001	0.999	0.000
T87.3 Neuroma of amputation stump	0.000	0.999	0.001
M87.85 Other osteonecrosis (Pelvic region and thigh)	0.001	0.999	0.000
C18.8 Overlapping lesion of colon	0.000	0.999	0.001
H26.1 Traumatic cataract	0.001	0.999	0.000
T87 Complications peculiar to reattachment and amputation	0.000	0.999	0.001
M82.11 Osteoporosis in endocrine disorders (Shoulder region)	0.000	0.999	0.001
M87.89 Other osteonecrosis (Site unspecified)	0.001	0.999	0.000
M87.88 Other osteonecrosis (Other)	0.001	0.999	0.000
M87.87 Other osteonecrosis (Ankle and foot)	0.001	0.999	0.000
M87.84 Other osteonecrosis (Hand)	0.001	0.999	0.000
M87.83 Other osteonecrosis (Forearm)	0.001	0.999	0.000
M87.82 Other osteonecrosis (Upper arm)	0.001	0.999	0.000
M87.81 Other osteonecrosis (Shoulder region)	0.001	0.999	0.000
M87.80 Other osteonecrosis (Multiple sites)	0.001	0.999	0.000
M87.1 Osteonecrosis due to drugs	0.001	0.999	0.000
Q39.4 Oesophageal web	0.001	0.999	0.000
J96 Respiratory failure, not elsewhere classified	0.001	0.999	0.000
G97.8 Other postprocedural disorders of nervous system	0.000	0.999	0.001
M87.0 Idiopathic aseptic necrosis of bone	0.001	0.999	0.000
S76.4 Injury of other and unspecified muscles and tendons at thigh level	0.001	0.999	0.000
S86.2 Injury of muscle(s) and tendon(s) of anterior muscle group at lower leg level	0.001	0.999	0.000
S86.1 Injury of other muscle(s) and tendon(s) of posterior muscle group at lower leg level	0.001	0.999	0.000
M87.35 Other secondary osteonecrosis (Pelvic region and thigh)	0.001	0.999	0.000
F38.8 Other specified mood [affective] disorders	0.000	0.999	0.001
O86.3 Other genito-urinary tract infections following delivery	0.001	0.999	0.000
S83.5 Sprain and strain involving (anterior)(posterior) cruciate ligament of knee	0.001	0.999	0.000
S02.00 Fracture of vault of skull (closed)	0.000	0.999	0.001
I63.4 Cerebral infarction due to embolism of cerebral arteries	0.001	0.999	0.000
Q43.8 Other specified congenital malformations of intestine	0.001	0.999	0.000
S86.0 Injury of Achilles tendon	0.001	0.999	0.000
S86.7 Injury of multiple muscles and tendons at lower leg level	0.001	0.999	0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs	0.000	0.999	0.001
S06.30 Focal brain injury (without open intracranial wound)	0.000	0.999	0.001
S92.40 Fracture of great toe (closed)	0.001	0.999	0.000
C41.9 Bone and articular cartilage, unspecified	0.000	0.999	0.001
I87.2 Venous insufficiency (chronic) (peripheral)	0.001	0.999	0.000
J99.0 Rheumatoid lung disease	0.001	0.999	0.000
M81.4 Drug-induced osteoporosis	0.001	0.999	0.000
O86.8 Other specified puerperal infections	0.001	0.999	0.000
Z50.6 Orthoptic training	0.001	0.999	0.000
M87.39 Other secondary osteonecrosis (Site unspecified)	0.001	0.999	0.000
M87.38 Other secondary osteonecrosis (Other)	0.001	0.999	0.000
M87.37 Other secondary osteonecrosis (Ankle and foot)	0.001	0.999	0.000
M87.36 Other secondary osteonecrosis (Lower leg)	0.001	0.999	0.000
M87.34 Other secondary osteonecrosis (Hand)	0.001	0.999	0.000
M87.33 Other secondary osteonecrosis (Forearm)	0.001	0.999	0.000
M87.32 Other secondary osteonecrosis (Upper arm)	0.001	0.999	0.000
M87.31 Other secondary osteonecrosis (Shoulder region)	0.001	0.999	0.000
M87.30 Other secondary osteonecrosis (Multiple sites)	0.001	0.999	0.000
H57.0 Anomalies of pupillary function	0.001	0.999	0.000
H81 Disorders of vestibular function	0.001	0.999	0.000
K74.0 Hepatic fibrosis	0.000	0.999	0.001
O87.2 Haemorrhoids in the puerperium	0.000	0.999	0.001
O90.8 Other complications of the puerperium, not elsewhere classified	0.001	0.999	0.000
T87.2 Complications of other reattached body part	0.000	0.999	0.001
T87.1 Complications of reattached (part of) lower extremity	0.000	0.999	0.001
T87.0 Complications of reattached (part of) upper extremity	0.000	0.999	0.001
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified	0.001	0.999	0.000
S89 Other and unspecified injuries of lower leg	0.001	0.999	0.000
M81.40 Drug-induced osteoporosis (Multiple sites)	0.001	0.999	0.000
M87.19 Osteonecrosis due to drugs (Site unspecified)	0.001	0.999	0.000
M87.18 Osteonecrosis due to drugs (Other)	0.001	0.999	0.000
M87.17 Osteonecrosis due to drugs (Ankle and foot)	0.001	0.999	0.000
M87.16 Osteonecrosis due to drugs (Lower leg)	0.001	0.999	0.000
M87.15 Osteonecrosis due to drugs (Pelvic region and thigh)	0.001	0.999	0.000
M87.14 Osteonecrosis due to drugs (Hand)	0.001	0.999	0.000
M87.13 Osteonecrosis due to drugs (Forearm)	0.001	0.999	0.000
M87.12 Osteonecrosis due to drugs (Upper arm)	0.001	0.999	0.000
M87.11 Osteonecrosis due to drugs (Shoulder region)	0.001	0.999	0.000
M87.10 Osteonecrosis due to drugs (Multiple sites)	0.001	0.999	0.000
D02.0 Larynx	0.001	0.999	0.000
J96.9 Respiratory failure, unspecified	0.001	0.999	0.000
J96.1 Chronic respiratory failure	0.001	0.999	0.000
J96.0 Acute respiratory failure	0.001	0.999	0.000
O86.1 Other infection of genital tract following delivery	0.001	0.999	0.000
C21 Malignant neoplasm of anus and anal canal	0.001	0.999	0.000
M87.09 Idiopathic aseptic necrosis of bone (Site unspecified)	0.001	0.999	0.000
M87.08 Idiopathic aseptic necrosis of bone (Other)	0.001	0.999	0.000
M87.07 Idiopathic aseptic necrosis of bone (Ankle and foot)	0.001	0.999	0.000
M87.06 Idiopathic aseptic necrosis of bone (Lower leg)	0.001	0.999	0.000
M87.04 Idiopathic aseptic necrosis of bone (Hand)	0.001	0.999	0.000
M87.03 Idiopathic aseptic necrosis of bone (Forearm)	0.001	0.999	0.000
M87.02 Idiopathic aseptic necrosis of bone (Upper arm)	0.001	0.999	0.000
M87.01 Idiopathic aseptic necrosis of bone (Shoulder region)	0.001	0.999	0.000
M87.00 Idiopathic aseptic necrosis of bone (Multiple sites)	0.001	0.999	0.000
C18.0 Caecum	0.000	0.999	0.001
H95.1 Other disorders following mastoidectomy	0.001	0.999	0.000
N18.5 Chronic kidney disease, stage 5	0.000	0.999	0.001
Q18.1 Preauricular sinus and cyst	0.001	0.999	0.000
S86.9 Injury of unspecified muscle and tendon at lower leg level	0.001	0.999	0.000
T51.0 Ethanol	0.001	0.999	0.000
S86.00 Unspecified injury of Achilles tendon	0.001	0.999	0.000
C41.4 Pelvic bones, sacrum and coccyx	0.000	0.999	0.001
D41.9 Urinary organ, unspecified	0.000	0.999	0.001
D41.7 Other urinary organs	0.000	0.999	0.001
D41.3 Urethra	0.000	0.999	0.001
H95.9 Postprocedural disorder of ear and mastoid process, unspecified	0.001	0.999	0.000
S86.3 Injury of muscle(s) and tendon(s) of peroneal muscle group at lower leg level	0.001	0.999	0.000
I31 Other diseases of pericardium	0.001	0.999	0.000
M81.48 Drug-induced osteoporosis (Other)	0.001	0.999	0.000
M81.47 Drug-induced osteoporosis (Ankle and foot)	0.001	0.999	0.000
M81.46 Drug-induced osteoporosis (Lower leg)	0.001	0.999	0.000
M81.45 Drug-induced osteoporosis (Pelvic region and thigh)	0.001	0.999	0.000
M81.44 Drug-induced osteoporosis (Hand)	0.001	0.999	0.000
M81.43 Drug-induced osteoporosis (Forearm)	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations