TreeWAS – Variant ID: rs4938174

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
H33.3 Retinal breaks without detachment	0.336	0.664	0.000
H33.0 Retinal detachment with retinal break	0.323	0.677	0.000
H33 Retinal detachments and breaks	0.319	0.681	0.000
H33.4 Traction detachment of retina	0.228	0.772	0.000
H33.2 Serous retinal detachment	0.219	0.781	0.000
H33.5 Other retinal detachments	0.210	0.790	0.000
H33.1 Retinoschisis and retinal cysts	0.173	0.827	0.000
R29.8 Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems	0.073	0.927	0.000
H30-H36 Disorders of choroid and retina	0.052	0.948	0.000
H31 Other disorders of choroid	0.041	0.958	0.000
H30 Chorioretinal inflammation	0.039	0.961	0.000
H32 Chorioretinal disorders in diseases classified elsewhere	0.037	0.963	0.000
H31.0 Chorioretinal scars	0.035	0.965	0.000
H31.9 Disorder of choroid, unspecified	0.033	0.967	0.000
H31.8 Other specified disorders of choroid	0.032	0.968	0.000
H30.2 Posterior cyclitis	0.030	0.969	0.000
H31.4 Choroidal detachment	0.030	0.970	0.000
H31.2 Hereditary choroidal dystrophy	0.030	0.970	0.000
H35 Other retinal disorders	0.029	0.971	0.000
H35.4 Peripheral retinal degeneration	0.028	0.971	0.000
H30.8 Other chorioretinal inflammations	0.028	0.972	0.000
H30.1 Disseminated chorioretinal inflammation	0.028	0.972	0.000
H30.0 Focal chorioretinal inflammation	0.028	0.972	0.000
H30.9 Chorioretinal inflammation, unspecified	0.028	0.972	0.000
H31.3 Choroidal haemorrhage and rupture	0.028	0.972	0.000
H32.8 Other chorioretinal disorders in diseases classified elsewhere	0.027	0.973	0.000
H32.0 Chorioretinal inflammation in infectious and parasitic diseases classified elsewhere	0.027	0.973	0.000
H36 Retinal disorders in diseases classified elsewhere	0.025	0.975	0.000
H31.1 Choroidal degeneration	0.025	0.975	0.000
H35.6 Retinal haemorrhage	0.023	0.976	0.000
H35.2 Other proliferative retinopathy	0.023	0.977	0.000
L84 Corns and callosities	0.000	0.977	0.023
H35.1 Retinopathy of prematurity	0.021	0.979	0.000
H40.1 Primary open-angle glaucoma	0.000	0.979	0.021
H35.0 Background retinopathy and retinal vascular changes	0.020	0.980	0.000
H43 Disorders of vitreous body	0.020	0.980	0.000
H43.1 Vitreous haemorrhage	0.019	0.981	0.000
H35.9 Retinal disorder, unspecified	0.019	0.981	0.000
H43.3 Other vitreous opacities	0.018	0.982	0.000
H36.8 Other retinal disorders in diseases classified elsewhere	0.018	0.982	0.000
H35.5 Hereditary retinal dystrophy	0.018	0.982	0.000
H43.8 Other disorders of vitreous body	0.018	0.982	0.000
H43-H45 Disorders of vitreous body and globe	0.017	0.983	0.000
H40 Glaucoma	0.000	0.983	0.017
H44 Disorders of globe	0.016	0.984	0.000
H40.2 Primary angle-closure glaucoma	0.000	0.984	0.016
H44.0 Purulent endophthalmitis	0.016	0.984	0.000
H43.9 Disorder of vitreous body, unspecified	0.016	0.984	0.000
H43.0 Vitreous prolapse	0.015	0.984	0.000
H40.9 Glaucoma, unspecified	0.000	0.985	0.015
H35.7 Separation of retinal layers	0.015	0.985	0.000
H34 Retinal vascular occlusions	0.013	0.987	0.000
H44.2 Degenerative myopia	0.013	0.987	0.000
H44.8 Other disorders of globe	0.013	0.987	0.000
H45 Disorders of vitreous body and globe in diseases classified elsewhere	0.012	0.987	0.000
I35.1 Aortic (valve) insufficiency	0.012	0.988	0.000
H40.6 Glaucoma secondary to drugs	0.000	0.988	0.012
H40.4 Glaucoma secondary to eye inflammation	0.000	0.988	0.012
H44.1 Other endophthalmitis	0.012	0.988	0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems	0.012	0.988	0.000
H40.5 Glaucoma secondary to other eye disorders	0.000	0.988	0.012
H35.8 Other specified retinal disorders	0.012	0.988	0.000
H44.9 Disorder of globe, unspecified	0.012	0.988	0.000
H44.7 Retained (old) intraocular foreign body, nonmagnetic	0.012	0.988	0.000
H44.6 Retained (old) intraocular foreign body, magnetic	0.012	0.988	0.000
H44.3 Other degenerative disorders of globe	0.012	0.988	0.000
H40.3 Glaucoma secondary to eye trauma	0.000	0.988	0.012
H72.9 Perforation of tympanic membrane, unspecified	0.012	0.988	0.000
H44.5 Degenerated conditions of globe	0.011	0.988	0.000
H43.2 Crystalline deposits in vitreous body	0.011	0.989	0.000
H11 Other disorders of conjunctiva	0.011	0.989	0.000
H11.4 Other conjunctival vascular disorders and cysts	0.011	0.989	0.000
H40-H42 Glaucoma	0.004	0.989	0.007
H40.8 Other glaucoma	0.000	0.990	0.010
H11.9 Disorder of conjunctiva, unspecified	0.010	0.990	0.000
H44.4 Hypotony of eye	0.010	0.990	0.000
Z92.4 Personal history of major surgery, not elsewhere classified	0.000	0.990	0.010
H11.1 Conjunctival degenerations and deposits	0.010	0.990	0.000
H34.0 Transient retinal artery occlusion	0.010	0.990	0.000
H10-H13 Disorders of conjunctiva	0.010	0.990	0.000
Chapter VII Diseases of the eye and adnexa	0.009	0.991	0.000
H45.8 Other disorders of vitreous body and globe in diseases classified elsewhere	0.009	0.991	0.000
H45.1 Endophthalmitis in diseases classified elsewhere	0.009	0.991	0.000
H45.0 Vitreous haemorrhage in diseases classified elsewhere	0.009	0.991	0.000
H34.1 Central retinal artery occlusion	0.009	0.991	0.000
R29.4 Clicking hip	0.009	0.991	0.000
R29.3 Abnormal posture	0.009	0.991	0.000
R29.0 Tetany	0.009	0.991	0.000
R29.1 Meningismus	0.009	0.991	0.000
H11.2 Conjunctival scars	0.009	0.991	0.000
H11.3 Conjunctival haemorrhage	0.009	0.991	0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.008	0.992	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.008	0.992	0.000
H40.0 Glaucoma suspect	0.000	0.992	0.008
H42 Glaucoma in diseases classified elsewhere	0.003	0.992	0.005
H34.9 Retinal vascular occlusion, unspecified	0.008	0.992	0.000
R29.2 Abnormal reflex	0.008	0.992	0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.008	0.992	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.008	0.992	0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.008	0.992	0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.008	0.992	0.000
T46.4 Angiotensin-converting-enzyme inhibitors	0.008	0.992	0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.008	0.992	0.000
H13 Disorders of conjunctiva in diseases classified elsewhere	0.007	0.993	0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.007	0.993	0.000
T42.4 Benzodiazepines	0.007	0.993	0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.007	0.993	0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.007	0.993	0.000
Z63.8 Other specified problems related to primary support group	0.007	0.993	0.000
S32.00 Fracture of lumbar vertebra (closed)	0.007	0.993	0.000
H11.8 Other specified disorders of conjunctiva	0.007	0.993	0.000
H34.2 Other retinal artery occlusions	0.007	0.993	0.000
T36 Poisoning by systemic antibiotics	0.007	0.993	0.000
T40.4 Other synthetic narcotics	0.007	0.993	0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.007	0.993	0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.007	0.993	0.000
T47.1 Other antacids and anti-gastric-secretion drugs	0.007	0.993	0.000
T40.1 Heroin	0.007	0.993	0.000
H72 Perforation of tympanic membrane	0.007	0.993	0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.006	0.993	0.000
T40.5 Cocaine	0.006	0.994	0.000
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.006	0.994	0.000
T47.0 Histamine H(2)-receptor antagonists	0.006	0.994	0.000
Z63.7 Other stressful life events affecting family and household	0.006	0.994	0.000
T42.1 Iminostilbenes	0.006	0.994	0.000
H36.0 Diabetic retinopathy	0.006	0.994	0.000
I46.0 Cardiac arrest with successful resuscitation	0.006	0.994	0.000
Z63 Other problems related to primary support group, including family circumstances	0.006	0.994	0.000
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.006	0.994	0.000
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.006	0.994	0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.006	0.994	0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.006	0.994	0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.006	0.994	0.000
T44.1 Other parasympathomimetics [cholinergics]	0.006	0.994	0.000
T44.0 Anticholinesterase agents	0.006	0.994	0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.006	0.994	0.000
T41 Poisoning by anaesthetics and therapeutic gases	0.006	0.994	0.000
H42.8 Glaucoma in other diseases classified elsewhere	0.002	0.994	0.004
H42.0 Glaucoma in endocrine, nutritional and metabolic diseases	0.002	0.994	0.004
T43.3 Phenothiazine antipsychotics and neuroleptics	0.006	0.994	0.000
T46.5 Other antihypertensive drugs, not elsewhere classified	0.006	0.994	0.000
H11.0 Pterygium	0.006	0.994	0.000
T43.4 Butyrophenone and thioxanthene neuroleptics	0.006	0.994	0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.006	0.994	0.000
T46.8 Antivaricose drugs, including sclerosing agents	0.006	0.994	0.000
T46.7 Peripheral vasodilators	0.006	0.994	0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.006	0.994	0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.006	0.994	0.000
H46-H48 Disorders of optic nerve and visual pathways	0.006	0.994	0.000
T36.3 Macrolides	0.006	0.994	0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.006	0.994	0.000
T42.5 Mixed antiepileptics, not elsewhere classified	0.006	0.994	0.000
T42.3 Barbiturates	0.006	0.994	0.000
T42.2 Succinimides and oxazolidinediones	0.006	0.994	0.000
T46.3 Coronary vasodilators, not elsewhere classified	0.006	0.994	0.000
T46.1 Calcium-channel blockers	0.006	0.994	0.000
T45.5 Anticoagulants	0.006	0.994	0.000
H10 Conjunctivitis	0.006	0.994	0.000
S32.0 Fracture of lumbar vertebra	0.006	0.994	0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.006	0.994	0.000
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.006	0.994	0.000
T47.8 Other agents primarily affecting the gastro-intestinal system	0.006	0.994	0.000
T47.7 Emetics	0.006	0.994	0.000
T47.6 Antidiarrhoeal drugs	0.006	0.994	0.000
T47.5 Digestants	0.006	0.994	0.000
T47.4 Other laxatives	0.006	0.994	0.000
T47.3 Saline and osmotic laxatives	0.006	0.994	0.000
T47.2 Stimulant laxatives	0.006	0.994	0.000
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.006	0.994	0.000
T40.8 Lysergide [LSD]	0.006	0.994	0.000
T40.7 Cannabis (derivatives)	0.006	0.994	0.000
T40.3 Methadone	0.006	0.994	0.000
T40.0 Opium	0.006	0.994	0.000
T45.0 Antiallergic and antiemetic drugs	0.006	0.994	0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.006	0.994	0.000
T43.5 Other and unspecified antipsychotics and neuroleptics	0.006	0.994	0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.005	0.994	0.000
M47.92 Spondylosis, unspecified (Cervical region)	0.000	0.994	0.006
Z74.0 Reduced mobility	0.000	0.994	0.006
H13.8 Other disorders of conjunctiva in diseases classified elsewhere	0.005	0.995	0.000
H13.2 Conjunctivitis in other diseases classified elsewhere	0.005	0.995	0.000
H13.1 Conjunctivitis in infectious and parasitic diseases classified elsewhere	0.005	0.995	0.000
H13.0 Filarial infection of conjunctiva	0.005	0.995	0.000
Z63.6 Dependent relative needing care at home	0.005	0.995	0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.005	0.995	0.000
H13.3 Ocular pemphigoid	0.005	0.995	0.000
O63.0 Prolonged first stage (of labour)	0.000	0.995	0.005
T43.0 Tricyclic and tetracyclic antidepressants	0.005	0.995	0.000
T43.9 Psychotropic drug, unspecified	0.005	0.995	0.000
T43.8 Other psychotropic drugs, not elsewhere classified	0.005	0.995	0.000
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.005	0.995	0.000
H72.0 Central perforation of tympanic membrane	0.005	0.995	0.000
H72.8 Other perforations of tympanic membrane	0.005	0.995	0.000
T36.9 Systemic antibiotic, unspecified	0.005	0.995	0.000
T36.8 Other systemic antibiotics	0.005	0.995	0.000
T36.7 Antifungal antibiotics, systemically used	0.005	0.995	0.000
T36.6 Rifamycins	0.005	0.995	0.000
T36.5 Aminoglycosides	0.005	0.995	0.000
T36.4 Tetracyclines	0.005	0.995	0.000
T36.2 Chloramphenicol group	0.005	0.995	0.000
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.005	0.995	0.000
T36.0 Penicillins	0.005	0.995	0.000
T45.9 Primarily systemic and haematological agent, unspecified	0.005	0.995	0.000
T45.8 Other primarily systemic and haematological agents	0.005	0.995	0.000
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.005	0.995	0.000
T45.6 Fibrinolysis-affecting drugs	0.005	0.995	0.000
T45.4 Iron and its compounds	0.005	0.995	0.000
T45.3 Enzymes, not elsewhere classified	0.005	0.995	0.000
T43.6 Psychostimulants with abuse potential	0.005	0.995	0.000
T42.0 Hydantoin derivatives	0.005	0.995	0.000
D04.6 Skin of upper limb, including shoulder	0.000	0.995	0.005
T49.9 Topical agent, unspecified	0.005	0.995	0.000
T49.8 Other topical agents	0.005	0.995	0.000
T49.7 Dental drugs, topically applied	0.005	0.995	0.000
T49.6 Otorhinolaryngological drugs and preparations	0.005	0.995	0.000
T49.5 Ophthalmological drugs and preparations	0.005	0.995	0.000
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.005	0.995	0.000
T49.3 Emollients, demulcents and protectants	0.005	0.995	0.000
T49.2 Local astringents and local detergents	0.005	0.995	0.000
T49.1 Antipruritics	0.005	0.995	0.000
T40.2 Other opioids	0.005	0.995	0.000
Z63.4 Disappearance and death of family member	0.005	0.995	0.000
S32 Fracture of lumbar spine and pelvis	0.005	0.995	0.000
T45.2 Vitamins, not elsewhere classified	0.005	0.995	0.000
T45.1 Antineoplastic and immunosuppressive drugs	0.005	0.995	0.000
D04 Carcinoma in situ of skin	0.000	0.995	0.005
O62.2 Other uterine inertia	0.000	0.995	0.005
W29.9 Unspecified place	0.000	0.995	0.005
Z63.9 Problem related to primary support group, unspecified	0.005	0.995	0.000
Z63.3 Absence of family member	0.005	0.995	0.000
Z63.2 Inadequate family support	0.005	0.995	0.000
Z63.1 Problems in relationship with parents and in-laws	0.005	0.995	0.000
T41.5 Therapeutic gases	0.005	0.995	0.000
T41.4 Anaesthetic, unspecified	0.005	0.995	0.000
T41.3 Local anaesthetics	0.005	0.995	0.000
T41.2 Other and unspecified general anaesthetics	0.005	0.995	0.000
T41.1 Intravenous anaesthetics	0.005	0.995	0.000
T41.0 Inhaled anaesthetics	0.005	0.995	0.000
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.005	0.995	0.000
T48.6 Antiasthmatics, not elsewhere classified	0.005	0.995	0.000
T48.5 Anti-common-cold drugs	0.005	0.995	0.000
T48.4 Expectorants	0.005	0.995	0.000
T48.3 Antitussives	0.005	0.995	0.000
T48.2 Other and unspecified agents primarily acting on muscles	0.005	0.995	0.000
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.005	0.995	0.000
T48.0 Oxytocic drugs	0.005	0.995	0.000
H53-H54 Visual disturbances and blindness	0.005	0.995	0.000
H72.2 Other marginal perforations of tympanic membrane	0.005	0.995	0.000
D04.3 Skin of other and unspecified parts of face	0.000	0.995	0.005
D04.5 Skin of trunk	0.000	0.995	0.005
H10.0 Mucopurulent conjunctivitis	0.004	0.995	0.000
H48 Disorders of optic [2nd] nerve and visual pathways in diseases classified elsewhere	0.004	0.995	0.000
S32.7 Multiple fractures of lumbar spine and pelvis	0.005	0.995	0.000
S06.50 Traumatic subdural haemorrhage (without open intracranial wound)	0.005	0.995	0.000
D04.7 Skin of lower limb, including hip	0.000	0.995	0.005
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.004	0.995	0.000
H10.3 Acute conjunctivitis, unspecified	0.004	0.996	0.000
H54.4 Blindness, one eye	0.004	0.996	0.000
S32.70 Multiple fractures of lumbar spine and pelvis (closed)	0.004	0.996	0.000
D36.1 Peripheral nerves and autonomic nervous system	0.004	0.996	0.000
T40.6 Other and unspecified narcotics	0.004	0.996	0.000
H10.8 Other conjunctivitis	0.004	0.996	0.000
H10.5 Blepharoconjunctivitis	0.004	0.996	0.000
H10.2 Other acute conjunctivitis	0.004	0.996	0.000
H10.1 Acute atopic conjunctivitis	0.004	0.996	0.000
H55-H59 Other disorders of eye and adnexa	0.004	0.996	0.000
S32.01 Fracture of lumbar vertebra (open)	0.004	0.996	0.000
K56.5 Intestinal adhesions [bands] with obstruction	0.004	0.996	0.000
H46 Optic neuritis	0.004	0.996	0.000
D36.7 Other specified sites	0.004	0.996	0.000
H72.1 Attic perforation of tympanic membrane	0.004	0.996	0.000
Z63.5 Disruption of family by separation and divorce	0.004	0.996	0.000
S32.5 Fracture of pubis	0.004	0.996	0.000
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.004	0.996	0.000
T37.5 Antiviral drugs	0.004	0.996	0.000
T37.4 Anthelminthics	0.004	0.996	0.000
T37.3 Other antiprotozoal drugs	0.004	0.996	0.000
T37.2 Antimalarials and drugs acting on other blood protozoa	0.004	0.996	0.000
T37.1 Antimycobacterial drugs	0.004	0.996	0.000
T37.0 Sulphonamides	0.004	0.996	0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.004	0.996	0.000
T50.8 Diagnostic agents	0.004	0.996	0.000
T50.7 Analeptics and opioid receptor antagonists	0.004	0.996	0.000
T50.6 Antidotes and chelating agents, not elsewhere classified	0.004	0.996	0.000
T50.5 Appetite depressants	0.004	0.996	0.000
T50.3 Electrolytic, caloric and water-balance agents	0.004	0.996	0.000
T50.1 Loop [high-ceiling] diuretics	0.004	0.996	0.000
T50.0 Mineralocorticoids and their antagonists	0.004	0.996	0.000
S06.00 Concussion (without open intracranial wound)	0.004	0.996	0.000
O62.3 Precipitate labour	0.000	0.996	0.004
D04.4 Skin of scalp and neck	0.000	0.996	0.004
H10.4 Chronic conjunctivitis	0.004	0.996	0.000
T50.4 Drugs affecting uric acid metabolism	0.004	0.996	0.000
O62.4 Hypertonic, incoordinate and prolonged uterine contractions	0.000	0.996	0.004
O62 Abnormalities of forces of labour	0.000	0.996	0.004
H34.8 Other retinal vascular occlusions	0.004	0.996	0.000
M48.02 Spinal stenosis (Cervical region)	0.000	0.996	0.004
H54 Blindness and low vision	0.004	0.996	0.000
S32.50 Fracture of pubis (closed)	0.004	0.996	0.000
D04.1 Skin of eyelid, including canthus	0.000	0.996	0.004
S32.8 Fracture of other and unspecified parts of lumbar spine and pelvis	0.004	0.996	0.000
D36 Benign neoplasm of other and unspecified sites	0.004	0.996	0.000
Z63.0 Problems in relationship with spouse or partner	0.004	0.996	0.000
S32.1 Fracture of sacrum	0.004	0.996	0.000
H47 Other disorders of optic [2nd] nerve and visual pathways	0.004	0.996	0.000
D04.8 Skin of other sites	0.000	0.996	0.004
D04.0 Skin of lip	0.000	0.996	0.004
R10.3 Pain localised to other parts of lower abdomen	0.004	0.996	0.000
S32.2 Fracture of coccyx	0.004	0.996	0.000
S06.5 Traumatic subdural haemorrhage	0.004	0.996	0.000
H58 Other disorders of eye and adnexa in diseases classified elsewhere	0.004	0.996	0.000
T37.8 Other specified systemic anti-infectives and antiparasitics	0.003	0.996	0.000
S31.4 Open wound of vagina and vulva	0.004	0.996	0.000
H48.8 Other disorders of optic nerve and visual pathways in diseases classified elsewhere	0.003	0.996	0.000
H48.1 Retrobulbar neuritis in diseases classified elsewhere	0.003	0.996	0.000
H48.0 Optic atrophy in diseases classified elsewhere	0.003	0.996	0.000
Z61 Problems related to negative life events in childhood	0.004	0.996	0.000
S32.71 Multiple fractures of lumbar spine and pelvis (open)	0.003	0.996	0.000
H47.0 Disorders of optic nerve, not elsewhere classified	0.003	0.996	0.000
S06.0 Concussion	0.003	0.996	0.000
K92.1 Melaena	0.004	0.996	0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances	0.003	0.997	0.000
D04.9 Skin, unspecified	0.000	0.997	0.003
H54.1 Blindness, one eye, low vision, other eye	0.003	0.997	0.000
S31 Open wound of abdomen, lower back and pelvis	0.003	0.997	0.000
Y43.0 Antiallergic and antiemetic drugs	0.000	0.997	0.003
C45.0 Mesothelioma of pleura	0.003	0.997	0.000
S32.3 Fracture of ilium	0.003	0.997	0.000
M79.84 Other specified soft tissue disorders (Hand)	0.003	0.997	0.000
S32.51 Fracture of pubis (open)	0.003	0.997	0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.003	0.997	0.000
T38.9 Other and unspecified hormone antagonists	0.003	0.997	0.000
T38.8 Other and unspecified hormones and their synthetic substitutes	0.003	0.997	0.000
T38.7 Androgens and anabolic congeners	0.003	0.997	0.000
T38.5 Other oestrogens and progestogens	0.003	0.997	0.000
T38.4 Oral contraceptives	0.003	0.997	0.000
T38.2 Antithyroid drugs	0.003	0.997	0.000
T38.0 Glucocorticoids and synthetic analogues	0.003	0.997	0.000
Y43.1 Antineoplastic antimetabolites	0.000	0.997	0.003
D36.0 Lymph nodes	0.003	0.997	0.000
H54.0 Blindness, both eyes	0.003	0.997	0.000
D04.2 Skin of ear and external auricular canal	0.000	0.997	0.003
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.003	0.997	0.000
Z61.5 Problems related to alleged sexual abuse of child by person outside primary support group	0.003	0.997	0.000
Z61.4 Problems related to alleged sexual abuse of child by person within primary support group	0.003	0.997	0.000
D36.9 Benign neoplasm of unspecified site	0.003	0.997	0.000
O62.8 Other abnormalities of forces of labour	0.000	0.997	0.003
O62.1 Secondary uterine inertia	0.000	0.997	0.003
Z61.6 Problems related to alleged physical abuse of child	0.003	0.997	0.000
H58.8 Visual disturbances in diseases classified elsewhere	0.003	0.997	0.000
H65-H75 Diseases of middle ear and mastoid	0.003	0.997	0.000
C84.5 Other and unspecified T-cell lymphomas	0.003	0.997	0.000
S32.80 Fracture of other and unspecified parts of lumbar spine and pelvis (closed)	0.003	0.997	0.000
O62.9 Abnormality of forces of labour, unspecified	0.000	0.997	0.003
S06 Intracranial injury	0.003	0.997	0.000
Z59 Problems related to housing and economic circumstances	0.003	0.997	0.000
H54.3 Unqualified visual loss, both eyes	0.003	0.997	0.000
S32.81 Fracture of other and unspecified parts of lumbar spine and pelvis (open)	0.003	0.997	0.000
H59 Postprocedural disorders of eye and adnexa, not elsewhere classified	0.003	0.997	0.000
T50.9 Other and unspecified drugs, medicaments and biological substances	0.003	0.997	0.000
S32.11 Fracture of sacrum (open)	0.003	0.997	0.000
S32.10 Fracture of sacrum (closed)	0.003	0.997	0.000
H47.7 Disorder of visual pathways, unspecified	0.003	0.997	0.000
H47.6 Disorders of visual cortex	0.003	0.997	0.000
H47.5 Disorders of other visual pathways	0.003	0.997	0.000
H47.4 Disorders of optic chiasm	0.003	0.997	0.000
M21.07 Valgus deformity, not elsewhere classified (Ankle and foot)	0.000	0.997	0.003
S39 Other and unspecified injuries of abdomen, lower back and pelvis	0.003	0.997	0.000
M94.88 Other specified disorders of cartilage (Other)	0.003	0.997	0.000
S32.21 Fracture of coccyx (open)	0.003	0.997	0.000
S32.20 Fracture of coccyx (closed)	0.003	0.997	0.000
S06.51 Traumatic subdural haemorrhage (with open intracranial wound)	0.003	0.997	0.000
T43.2 Other and unspecified antidepressants	0.003	0.997	0.000
N63 Unspecified lump in breast	0.000	0.997	0.003
Z58 Problems related to physical environment	0.003	0.997	0.000
H54.5 Low vision, one eye	0.003	0.997	0.000
H58.9 Other specified disorders of eye and adnexa in diseases classified elsewhere	0.003	0.997	0.000
H58.1 Visual disturbances in diseases classified elsewhere	0.003	0.997	0.000
H58.0 Anomalies of pupillary function in diseases classified elsewhere	0.003	0.997	0.000
L98.8 Other specified disorders of skin and subcutaneous tissue	0.000	0.997	0.003
Z89.4 Acquired absence of foot and ankle	0.003	0.997	0.000
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis	0.003	0.997	0.000
S31.3 Open wound of scrotum and testes	0.003	0.997	0.000
T38.1 Thyroid hormones and substitutes	0.003	0.997	0.000
S31.0 Open wound of lower back and pelvis	0.003	0.997	0.000
S32.4 Fracture of acetabulum	0.003	0.997	0.000
Z64 Problems related to certain psychosocial circumstances	0.003	0.997	0.000
Z59.9 Problem relating to housing and economic circumstances, unspecified	0.003	0.997	0.000
Z61.9 Negative life events in childhood, unspecified	0.003	0.997	0.000
Z61.8 Other negative life events in childhood	0.003	0.997	0.000
Z61.7 Personal frightening experience in childhood	0.003	0.997	0.000
Z61.3 Events resulting in loss of self-esteem in childhood	0.003	0.997	0.000
Z61.2 Altered pattern of family relationships in childhood	0.003	0.997	0.000
Z61.1 Removal from home in childhood	0.003	0.997	0.000
Z61.0 Loss of love relationship in childhood	0.003	0.997	0.000
Z81.8 Family history of other mental and behavioural disorders	0.000	0.997	0.003
H69 Other disorders of Eustachian tube	0.003	0.997	0.000
H54.6 Unqualified visual loss, one eye	0.003	0.997	0.000
S06.9 Intracranial injury, unspecified	0.003	0.997	0.000
S06.01 Concussion (with open intracranial wound)	0.003	0.997	0.000
H10.9 Conjunctivitis, unspecified	0.003	0.997	0.000
H54.2 Low vision, both eyes	0.003	0.997	0.000
S06.2 Diffuse brain injury	0.003	0.997	0.000
H55 Nystagmus and other irregular eye movements	0.003	0.997	0.000
M90.75 Fracture of bone in neoplastic disease (Pelvic region and thigh)	0.003	0.997	0.000
T85.6 Mechanical complication of other specified internal prosthetic devices, implants and grafts	0.003	0.997	0.000
C84.4 Peripheral T-cell lymphoma	0.003	0.997	0.000
H74.0 Tympanosclerosis	0.003	0.997	0.000
Z58.8 Other problems related to physical environment	0.003	0.997	0.000
Z62 Other problems related to upbringing	0.003	0.997	0.000
Z55 Problems related to education and literacy	0.003	0.997	0.000
S31.7 Multiple open wounds of abdomen, lower back and pelvis	0.003	0.997	0.000
S31.5 Open wound of other and unspecified external genital organs	0.003	0.997	0.000
S31.2 Open wound of penis	0.003	0.997	0.000
Z65 Problems related to other psychosocial circumstances	0.003	0.997	0.000
S32.31 Fracture of ilium (open)	0.002	0.997	0.000
H47.3 Other disorders of optic disk	0.003	0.997	0.000
S06.90 Intracranial injury, unspecified (without open intracranial wound)	0.003	0.997	0.000
K62.6 Ulcer of anus and rectum	0.000	0.997	0.003
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis	0.003	0.997	0.000
S37 Injury of urinary and pelvic organs	0.003	0.997	0.000
S35 Injury of blood vessels at abdomen, lower back and pelvis level	0.003	0.997	0.000
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level	0.003	0.997	0.000
H47.2 Optic atrophy	0.002	0.997	0.000
S06.1 Traumatic cerebral oedema	0.003	0.997	0.000
Z56 Problems related to employment and unemployment	0.003	0.997	0.000
S06.20 Diffuse brain injury (without open intracranial wound)	0.003	0.997	0.000
D13.0 Oesophagus	0.000	0.997	0.003
O62.0 Primary inadequate contractions	0.000	0.997	0.003
S33.5 Sprain and strain of lumbar spine	0.002	0.997	0.000
H74.9 Disorder of middle ear and mastoid, unspecified	0.003	0.997	0.000
H06.2 Dysthyroid exophthalmos	0.003	0.997	0.000
S39.0 Injury of muscle and tendon of abdomen, lower back and pelvis	0.003	0.997	0.000
H74 Other disorders of middle ear and mastoid	0.003	0.997	0.000
S39.9 Unspecified injury of abdomen, lower back and pelvis	0.003	0.997	0.000
H66.4 Suppurative otitis media, unspecified	0.002	0.997	0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere	0.002	0.997	0.000
H68 Eustachian salpingitis and obstruction	0.002	0.997	0.000
H67 Otitis media in diseases classified elsewhere	0.002	0.997	0.000
S36 Injury of intra-abdominal organs	0.002	0.997	0.000
H66 Suppurative and unspecified otitis media	0.003	0.997	0.000
S06.7 Intracranial injury with prolonged coma	0.002	0.997	0.000
S31.8 Open wound of other and unspecified parts of abdomen	0.002	0.997	0.000
Z59.7 Insufficient social insurance and welfare support	0.002	0.997	0.000
Z59.6 Low income	0.002	0.997	0.000
Z59.5 Extreme poverty	0.002	0.997	0.000
Z59.4 Lack of adequate food	0.002	0.997	0.000
Z59.3 Problems related to living in residential institution	0.002	0.997	0.000
Z59.2 Discord with neighbours, lodgers and landlord	0.002	0.997	0.000
Z59.1 Inadequate housing	0.002	0.997	0.000
H69.8 Other specified disorders of Eustachian tube	0.002	0.998	0.000
S06.4 Epidural haemorrhage	0.002	0.998	0.000
Z59.8 Other problems relating to housing and economic circumstances	0.002	0.998	0.000
Z59.0 Homelessness	0.002	0.998	0.000
Z58.7 Exposure to tobacco smoke	0.002	0.998	0.000
H69.9 Eustachian tube disorder, unspecified	0.002	0.998	0.000
O72.2 Delayed and secondary postpartum haemorrhage	0.000	0.998	0.002
S06.8 Other intracranial injuries	0.002	0.998	0.000
Z56.6 Other physical and mental strain related to work	0.002	0.998	0.000
Z64.0 Problems related to unwanted pregnancy	0.002	0.998	0.000
H52.2 Astigmatism	0.000	0.998	0.002
S39.7 Other multiple injuries of abdomen, lower back and pelvis	0.002	0.998	0.000
S39.6 Injury of intra-abdominal organ(s) with pelvic organ(s)	0.002	0.998	0.000
H73 Other disorders of tympanic membrane	0.002	0.998	0.000
H70 Mastoiditis and related conditions	0.002	0.998	0.000
S39.8 Other specified injuries of abdomen, lower back and pelvis	0.002	0.998	0.000
Z58.9 Problem related to physical environment, unspecified	0.002	0.998	0.000
Z58.6 Inadequate drinking-water supply	0.002	0.998	0.000
Z58.4 Exposure to radiation	0.002	0.998	0.000
Z58.3 Exposure to soil pollution	0.002	0.998	0.000
Z58.2 Exposure to water pollution	0.002	0.998	0.000
Z58.0 Exposure to noise	0.002	0.998	0.000
M94.26 Chondromalacia (Lower leg)	0.002	0.998	0.000
S33.7 Sprain and strain of other and unspecified parts of lumbar spine and pelvis	0.002	0.998	0.000
S33.6 Sprain and strain of sacro-iliac joint	0.002	0.998	0.000
S33.4 Traumatic rupture of symphysis pubis	0.002	0.998	0.000
S33.3 Dislocation of other and unspecified parts of lumbar spine and pelvis	0.002	0.998	0.000
S33.2 Dislocation of sacro-iliac and sacrococcygeal joint	0.002	0.998	0.000
S33.1 Dislocation of lumbar vertebra	0.002	0.998	0.000
S33.0 Traumatic rupture of lumbar intervertebral disk	0.002	0.998	0.000
C84 Peripheral and cutaneous T-cell lymphomas	0.002	0.998	0.000
S32.41 Fracture of acetabulum (open)	0.002	0.998	0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.002	0.998	0.000
H59.9 Postprocedural disorder of eye and adnexa, unspecified	0.002	0.998	0.000
Z64.4 Discord with counsellors	0.002	0.998	0.000
Z64.3 Seeking and accepting behavioural and psychological interventions known to be hazardous and harmful	0.002	0.998	0.000
Z64.2 Seeking and accepting physical, nutritional and chemical interventions known to be hazardous and harmful	0.002	0.998	0.000
Z64.1 Problems related to multiparity	0.002	0.998	0.000
S06.10 Traumatic cerebral oedema (without open intracranial wound)	0.002	0.998	0.000
Z58.5 Exposure to other pollution	0.002	0.998	0.000
S06.91 Intracranial injury, unspecified (with open intracranial wound)	0.002	0.998	0.000
H59.0 Vitreous syndrome following cataract surgery	0.002	0.998	0.000
H69.0 Patulous Eustachian tube	0.002	0.998	0.000
H73.1 Chronic myringitis	0.002	0.998	0.000
I33.0 Acute and subacute infective endocarditis	0.002	0.998	0.000
S31.1 Open wound of abdominal wall	0.002	0.998	0.000
S06.21 Diffuse brain injury (with open intracranial wound)	0.002	0.998	0.000
S19.9 Unspecified injury of neck	0.002	0.998	0.000
S37.2 Injury of bladder	0.002	0.998	0.000
S32.30 Fracture of ilium (closed)	0.002	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations