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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs494207
log Bayes Factor = 27.0929
Chromosome 10   position 44,741,256  (GRCh37) Explore rs494207 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
I25.1 Atherosclerotic heart disease
0.000 0.000 1.000
I25 Chronic ischaemic heart disease
0.000 0.000 1.000
I21 Acute myocardial infarction
0.000 0.000 1.000
I20-I25 Ischaemic heart diseases
0.000 0.000 1.000
Z95.1 Presence of aortocoronary bypass graft
0.000 0.000 1.000
I21.9 Acute myocardial infarction, unspecified
0.000 0.000 1.000
I20 Angina pectoris
0.000 0.000 1.000
I25.8 Other forms of chronic ischaemic heart disease
0.000 0.000 1.000
I25.9 Chronic ischaemic heart disease, unspecified
0.000 0.002 0.998
I22 Subsequent myocardial infarction
0.000 0.003 0.997
Z95 Presence of cardiac and vascular implants and grafts
0.000 0.003 0.997
I20.9 Angina pectoris, unspecified
0.000 0.003 0.997
I20.8 Other forms of angina pectoris
0.000 0.003 0.997
Z95.5 Presence of coronary angioplasty implant and graft
0.000 0.003 0.997
I25.2 Old myocardial infarction
0.000 0.004 0.996
I21.0 Acute transmural myocardial infarction of anterior wall
0.000 0.010 0.990
I25.5 Ischaemic cardiomyopathy
0.000 0.021 0.979
I22.9 Subsequent myocardial infarction of unspecified site
0.000 0.024 0.976
Z95.9 Presence of cardiac and vascular implant and graft, unspecified
0.000 0.061 0.939
I21.1 Acute transmural myocardial infarction of inferior wall
0.000 0.091 0.909
I22.0 Subsequent myocardial infarction of anterior wall
0.000 0.100 0.900
Z95.0 Presence of cardiac pacemaker
0.000 0.108 0.892
I22.1 Subsequent myocardial infarction of inferior wall
0.000 0.141 0.859
I22.8 Subsequent myocardial infarction of other sites
0.000 0.145 0.855
Z95.8 Presence of other cardiac and vascular implants and grafts
0.000 0.174 0.826
I24 Other acute ischaemic heart diseases
0.000 0.178 0.822
I25.3 Aneurysm of heart
0.000 0.178 0.822
I21.3 Acute transmural myocardial infarction of unspecified site
0.000 0.274 0.726
I21.X Presumed acute myicardial infaction (unconfirmed)
0.000 0.283 0.717
I25.6 Silent myocardial ischaemia
0.000 0.283 0.717
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.000 0.328 0.672
I23 Certain current complications following acute myocardial infarction
0.000 0.359 0.640
I25.0 Atherosclerotic cardiovascular disease, so described
0.000 0.375 0.625
Z95.3 Presence of xenogenic heart valve
0.000 0.384 0.616
I24.8 Other forms of acute ischaemic heart disease
0.000 0.386 0.614
I20.1 Angina pectoris with documented spasm
0.000 0.391 0.609
I24.9 Acute ischaemic heart disease, unspecified
0.000 0.399 0.601
I24.1 Dressler's syndrome
0.000 0.410 0.590
I25.4 Coronary artery aneurysm
0.000 0.464 0.536
I21.2 Acute transmural myocardial infarction of other sites
0.000 0.472 0.527
I21.4 Acute subendocardial myocardial infarction
0.000 0.483 0.517
I23.6 Thrombosis of atrium, auricular appendage and ventricle as current complications following acute myocardial infarction
0.000 0.541 0.459
I23.5 Rupture of papillary muscle as current complication following acute myocardial infarction
0.000 0.541 0.459
I23.4 Rupture of chordae tendineae as current complication following acute myocardial infarction
0.000 0.541 0.459
I23.3 Rupture of cardiac wall without haemopericardium as current complication following acute myocardial infarction
0.000 0.541 0.459
I23.2 Ventricular septal defect as current complication following acute myocardial infarction
0.000 0.541 0.459
I23.1 Atrial septal defect as current complication following acute myocardial infarction
0.000 0.541 0.459
I23.0 Haemopericardium as current complication following acute myocardial infarction
0.000 0.541 0.459
I23.8 Other current complications following acute myocardial infarction
0.000 0.617 0.382
I20.0 Unstable angina
0.000 0.619 0.381
Z82.4 Family history of ischaemic heart disease and other diseases of the circulatory system
0.000 0.662 0.338
Z82 Family history of certain disabilities and chronic diseases leading to disablement
0.000 0.778 0.222
E78.0 Pure hypercholesterolaemia
0.000 0.792 0.208
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.793 0.207
E20-E35 Disorders of other endocrine glands
0.000 0.793 0.207
E70-E90 Metabolic disorders
0.000 0.794 0.206
E87 Other disorders of fluid, electrolyte and acid-base balance
0.000 0.798 0.202
E10-E14 Diabetes mellitus
0.000 0.799 0.201
E11 Non-insulin-dependent diabetes mellitus
0.000 0.799 0.201
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.799 0.201
Z82.3 Family history of stroke
0.000 0.805 0.195
E87.7 Fluid overload
0.000 0.812 0.188
E22 Hyperfunction of pituitary gland
0.000 0.814 0.186
E11.2 With renal complications
0.000 0.815 0.185
E11.4 With neurological complications
0.000 0.817 0.183
E87.2 Acidosis
0.000 0.818 0.182
Z95.2 Presence of prosthetic heart valve
0.000 0.819 0.181
E00-E07 Disorders of thyroid gland
0.000 0.819 0.181
E87.1 Hypo-osmolality and hyponatraemia
0.000 0.820 0.180
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.821 0.179
E24 Cushing's syndrome
0.000 0.822 0.178
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.823 0.177
E13 Other specified diabetes mellitus
0.000 0.823 0.177
E23 Hypofunction and other disorders of pituitary gland
0.000 0.823 0.177
Z82.7 Family history of congenital malformations, deformations and chromosomal abnormalities
0.000 0.824 0.176
E87.0 Hyperosmolality and hypernatraemia
0.000 0.829 0.171
E11.3 With ophthalmic complications
0.000 0.831 0.169
Z95.4 Presence of other heart-valve replacement
0.001 0.831 0.168
E26 Hyperaldosteronism
0.000 0.833 0.167
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.835 0.165
Z82.6 Family history of arthritis and other diseases of the musculoskeletal system and connective tissue
0.000 0.836 0.164
E83 Disorders of mineral metabolism
0.000 0.839 0.161
E21.0 Primary hyperparathyroidism
0.000 0.840 0.160
E13.9 Without complications
0.000 0.840 0.160
E11.6 With other specified complications
0.000 0.840 0.160
Z82.8 Family history of other disabilities and chronic diseases leading to disablement, not elsewhere classified
0.000 0.840 0.160
Z82.2 Family history of deafness and hearing loss
0.000 0.840 0.160
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.841 0.159
E20 Hypoparathyroidism
0.000 0.841 0.159
E74 Other disorders of carbohydrate metabolism
0.000 0.842 0.158
E11.8 With unspecified complications
0.000 0.842 0.158
E24.9 Cushing's syndrome, unspecified
0.000 0.842 0.158
Z82.5 Family history of asthma and other chronic lower respiratory diseases
0.000 0.843 0.157
E50-E64 Other nutritional deficiencies
0.000 0.843 0.157
E27 Other disorders of adrenal gland
0.000 0.844 0.155
E05.9 Thyrotoxicosis, unspecified
0.000 0.845 0.155
E78.8 Other disorders of lipoprotein metabolism
0.000 0.846 0.154
E78.1 Pure hyperglyceridaemia
0.000 0.847 0.153
E11.0 With coma
0.000 0.848 0.152
E87.3 Alkalosis
0.000 0.848 0.152
E23.0 Hypopituitarism
0.000 0.848 0.152
E22.1 Hyperprolactinaemia
0.000 0.849 0.151
E11.5 With peripheral circulatory complications
0.000 0.849 0.151
Z82.0 Family history of epilepsy and other diseases of the nervous system
0.000 0.850 0.150
E34 Other endocrine disorders
0.000 0.851 0.149
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.851 0.148
E32 Diseases of thymus
0.000 0.851 0.148
E31 Polyglandular dysfunction
0.000 0.851 0.148
E30 Disorders of puberty, not elsewhere classified
0.000 0.851 0.148
E25 Adrenogenital disorders
0.000 0.851 0.148
E11.1 With ketoacidosis
0.000 0.852 0.148
E84 Cystic fibrosis
0.000 0.852 0.147
E79 Disorders of purine and pyrimidine metabolism
0.000 0.852 0.147
E77 Disorders of glycoprotein metabolism
0.000 0.852 0.147
E76 Disorders of glycosaminoglycan metabolism
0.000 0.852 0.147
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.000 0.852 0.147
E72 Other disorders of amino-acid metabolism
0.000 0.852 0.147
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.000 0.852 0.147
E70 Disorders of aromatic amino-acid metabolism
0.000 0.852 0.147
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.000 0.852 0.147
E04 Other non-toxic goitre
0.000 0.853 0.147
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.000 0.854 0.146
E29 Testicular dysfunction
0.000 0.854 0.146
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.855 0.145
E87.4 Mixed disorder of acid-base balance
0.000 0.855 0.145
E12 Malnutrition-related diabetes mellitus
0.000 0.856 0.144
Z82.1 Family history of blindness and visual loss
0.000 0.856 0.144
E11.7 With multiple complications
0.000 0.856 0.144
E78.6 Lipoprotein deficiency
0.000 0.856 0.144
E78.3 Hyperchylomicronaemia
0.000 0.856 0.144
E78.4 Other hyperlipidaemia
0.000 0.857 0.143
E22.0 Acromegaly and pituitary gigantism
0.000 0.859 0.141
E73 Lactose intolerance
0.000 0.859 0.141
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified
0.000 0.860 0.140
E26.0 Primary hyperaldosteronism
0.000 0.861 0.139
E04.2 Non-toxic multinodular goitre
0.000 0.862 0.138
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.864 0.136
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.867 0.133
E22.8 Other hyperfunction of pituitary gland
0.000 0.867 0.133
E23.2 Diabetes insipidus
0.000 0.867 0.133
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.867 0.133
E83.3 Disorders of phosphorus metabolism
0.000 0.869 0.130
E40-E46 Malnutrition
0.000 0.870 0.130
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.870 0.130
E00 Congenital iodine-deficiency syndrome
0.000 0.870 0.130
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.870 0.130
E83.5 Disorders of calcium metabolism
0.000 0.871 0.129
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.871 0.129
E21.4 Other specified disorders of parathyroid gland
0.000 0.871 0.129
E21.2 Other hyperparathyroidism
0.000 0.871 0.129
E24.8 Other Cushing's syndrome
0.000 0.872 0.128
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.872 0.128
E24.3 Ectopic ACTH syndrome
0.000 0.872 0.128
E24.2 Drug-induced Cushing's syndrome
0.000 0.872 0.128
E24.1 Nelson's syndrome
0.000 0.872 0.128
E24.0 Pituitary-dependent Cushing's disease
0.000 0.872 0.128
E05.8 Other thyrotoxicosis
0.000 0.873 0.127
E05.5 Thyroid crisis or storm
0.000 0.873 0.127
E05.4 Thyrotoxicosis factitia
0.000 0.873 0.127
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.873 0.127
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.873 0.127
E13.8 With unspecified complications
0.000 0.873 0.127
E13.7 With multiple complications
0.000 0.873 0.127
E13.6 With other specified complications
0.000 0.873 0.127
E13.5 With peripheral circulatory complications
0.000 0.873 0.127
E13.4 With neurological complications
0.000 0.873 0.127
E13.3 With ophthalmic complications
0.000 0.873 0.127
E13.2 With renal complications
0.000 0.873 0.127
E13.1 With ketoacidosis
0.000 0.873 0.127
E13.0 With coma
0.000 0.873 0.127
E89.0 Postprocedural hypothyroidism
0.000 0.873 0.127
E23.7 Disorder of pituitary gland, unspecified
0.000 0.873 0.127
E23.6 Other disorders of pituitary gland
0.000 0.873 0.127
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.873 0.127
E23.1 Drug-induced hypopituitarism
0.000 0.873 0.127
E85 Amyloidosis
0.000 0.874 0.126
E74.3 Other disorders of intestinal carbohydrate absorption
0.000 0.876 0.124
E20.9 Hypoparathyroidism, unspecified
0.000 0.876 0.124
E53 Deficiency of other B group vitamins
0.000 0.877 0.123
E78.2 Mixed hyperlipidaemia
0.000 0.877 0.123
E21.3 Hyperparathyroidism, unspecified
0.000 0.877 0.123
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.878 0.122
E78.9 Disorder of lipoprotein metabolism, unspecified
0.000 0.878 0.122
E26.9 Hyperaldosteronism, unspecified
0.000 0.880 0.120
E26.8 Other hyperaldosteronism
0.000 0.880 0.120
E26.1 Secondary hyperaldosteronism
0.000 0.880 0.120
E55 Vitamin D deficiency
0.000 0.880 0.120
E88 Other metabolic disorders
0.000 0.882 0.118
E65-E68 Obesity and other hyperalimentation
0.000 0.882 0.118
E83.9 Disorder of mineral metabolism, unspecified
0.000 0.884 0.115
E83.8 Other disorders of mineral metabolism
0.000 0.884 0.115
E83.2 Disorders of zinc metabolism
0.000 0.884 0.115
E83.0 Disorders of copper metabolism
0.000 0.884 0.115
E20.8 Other hypoparathyroidism
0.000 0.886 0.114
E20.1 Pseudohypoparathyroidism
0.000 0.886 0.114
E20.0 Idiopathic hypoparathyroidism
0.000 0.886 0.114
E27.8 Other specified disorders of adrenal gland
0.000 0.886 0.114
E74.9 Disorder of carbohydrate metabolism, unspecified
0.000 0.886 0.114
E74.8 Other specified disorders of carbohydrate metabolism
0.000 0.886 0.114
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.000 0.886 0.114
E74.2 Disorders of galactose metabolism
0.000 0.886 0.114
E74.1 Disorders of fructose metabolism
0.000 0.886 0.114
E74.0 Glycogen storage disease
0.000 0.886 0.114
E80 Disorders of porphyrin and bilirubin metabolism
0.000 0.887 0.113
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.887 0.113
E63 Other nutritional deficiencies
0.000 0.887 0.113
E56 Other vitamin deficiencies
0.000 0.887 0.113
E51 Thiamine deficiency
0.000 0.887 0.113
E50 Vitamin A deficiency
0.000 0.887 0.113
E60 Dietary zinc deficiency
0.000 0.887 0.113
E59 Dietary selenium deficiency
0.000 0.887 0.113
E58 Dietary calcium deficiency
0.000 0.887 0.113
E54 Ascorbic acid deficiency
0.000 0.887 0.113
E52 Niacin deficiency [pellagra]
0.000 0.887 0.113
E27.5 Adrenomedullary hyperfunction
0.000 0.888 0.112
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.888 0.112
E27.0 Other adrenocortical overactivity
0.000 0.888 0.112
E87.5 Hyperkalaemia
0.000 0.890 0.110
E27.9 Disorder of adrenal gland, unspecified
0.000 0.892 0.108
S60-S69 Injuries to the wrist and hand
0.000 0.892 0.108
E83.1 Disorders of iron metabolism
0.000 0.893 0.107
E34.9 Endocrine disorder, unspecified
0.000 0.893 0.107
E34.8 Other specified endocrine disorders
0.000 0.893 0.107
E34.5 Androgen resistance syndrome
0.000 0.893 0.107
E34.4 Constitutional tall stature
0.000 0.893 0.107
E34.3 Short stature, not elsewhere classified
0.000 0.893 0.107
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.893 0.107
E34.1 Other hypersecretion of intestinal hormones
0.000 0.893 0.107
E34.0 Carcinoid syndrome
0.000 0.893 0.107
E25.9 Adrenogenital disorder, unspecified
0.000 0.893 0.107
E25.8 Other adrenogenital disorders
0.000 0.893 0.107
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.893 0.107
E30.9 Disorder of puberty, unspecified
0.000 0.893 0.107
E30.8 Other disorders of puberty
0.000 0.893 0.107
E30.1 Precocious puberty
0.000 0.893 0.107
E30.0 Delayed puberty
0.000 0.893 0.107
E31.9 Polyglandular dysfunction, unspecified
0.000 0.893 0.107
E31.8 Other polyglandular dysfunction
0.000 0.893 0.107
E31.1 Polyglandular hyperfunction
0.000 0.893 0.107
E31.0 Autoimmune polyglandular failure
0.000 0.893 0.107
E32.9 Disease of thymus, unspecified
0.000 0.893 0.107
E32.8 Other diseases of thymus
0.000 0.893 0.107
E32.1 Abscess of thymus
0.000 0.893 0.107
E32.0 Persistent hyperplasia of thymus
0.000 0.893 0.107
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.893 0.107
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.893 0.107
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.893 0.107
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.000 0.894 0.106
E70.8 Other disorders of aromatic amino-acid metabolism
0.000 0.894 0.106
E70.3 Albinism
0.000 0.894 0.106
E70.2 Disorders of tyrosine metabolism
0.000 0.894 0.106
E70.1 Other hyperphenylalaninaemias
0.000 0.894 0.106
E70.0 Classical phenylketonuria
0.000 0.894 0.106
E71.3 Disorders of fatty-acid metabolism
0.000 0.894 0.106
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.000 0.894 0.106
E71.1 Other disorders of branched-chain amino-acid metabolism
0.000 0.894 0.106
E71.0 Maple-syrup-urine disease
0.000 0.894 0.106
E72.9 Disorder of amino-acid metabolism, unspecified
0.000 0.894 0.106
E72.8 Other specified disorders of amino-acid metabolism
0.000 0.894 0.106
E72.5 Disorders of glycine metabolism
0.000 0.894 0.106
E72.4 Disorders of ornithine metabolism
0.000 0.894 0.106
E72.3 Disorders of lysine and hydroxylysine metabolism
0.000 0.894 0.106
E72.2 Disorders of urea cycle metabolism
0.000 0.894 0.106
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.000 0.894 0.106
E72.0 Disorders of amino-acid transport
0.000 0.894 0.106
E75.6 Lipid storage disorder, unspecified
0.000 0.894 0.106
E75.5 Other lipid storage disorders
0.000 0.894 0.106
E75.4 Neuronal ceroid lipofuscinosis
0.000 0.894 0.106
E75.3 Sphingolipidosis, unspecified
0.000 0.894 0.106
E75.2 Other sphingolipidosis
0.000 0.894 0.106
E75.1 Other gangliosidosis
0.000 0.894 0.106
E75.0 GM2 gangliosidosis
0.000 0.894 0.106
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.000 0.894 0.106
E76.8 Other disorders of glucosaminoglycan metabolism
0.000 0.894 0.106
E76.3 Mucopolysaccharidosis, unspecified
0.000 0.894 0.106
E76.2 Other mucopolysaccharidoses
0.000 0.894 0.106
E76.1 Mucopolysaccharidosis, type II
0.000 0.894 0.106
E76.0 Mucopolysaccharidosis, type I
0.000 0.894 0.106
E77.9 Disorder of glycoprotein metabolism, unspecified
0.000 0.894 0.106
E77.8 Other disorders of glycoprotein metabolism
0.000 0.894 0.106
E77.1 Defects in glycoprotein degradation
0.000 0.894 0.106
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.000 0.894 0.106
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.000 0.894 0.106
E79.8 Other disorders of purine and pyrimidine metabolism
0.000 0.894 0.106
E79.1 Lesch-Nyhan syndrome
0.000 0.894 0.106
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.000 0.894 0.106
E84.9 Cystic fibrosis, unspecified
0.000 0.894 0.106
E84.8 Cystic fibrosis with other manifestations
0.000 0.894 0.106
E84.1 Cystic fibrosis with intestinal manifestations
0.000 0.894 0.106
E84.0 Cystic fibrosis with pulmonary manifestations
0.000 0.894 0.106
S61 Open wound of wrist and hand
0.000 0.894 0.106
E28 Ovarian dysfunction
0.000 0.894 0.106
E89.2 Postprocedural hypoparathyroidism
0.000 0.894 0.105
E04.8 Other specified non-toxic goitre
0.000 0.894 0.105
E89.9 Postprocedural endocrine and metabolic disorder, unspecified
0.000 0.895 0.105
E89.8 Other postprocedural endocrine and metabolic disorders
0.000 0.895 0.105
E89.6 Postprocedural adrenocortical(-medullary) hypofunction
0.000 0.895 0.105
E89.5 Postprocedural testicular hypofunction
0.000 0.895 0.105
E89.1 Postprocedural hypoinsulinaemia
0.000 0.895 0.105
E29.9 Testicular dysfunction, unspecified
0.000 0.895 0.105
E29.8 Other testicular dysfunction
0.000 0.895 0.105
E29.0 Testicular hyperfunction
0.000 0.895 0.105
E12.9 Without complications
0.000 0.896 0.104
E12.8 With unspecified complications
0.000 0.896 0.104
E12.7 With multiple complications
0.000 0.896 0.104
E12.6 With other specified complications
0.000 0.896 0.104
E12.5 With peripheral circulatory complications
0.000 0.896 0.104
E12.4 With neurological complications
0.000 0.896 0.104
E12.3 With ophthalmic complications
0.000 0.896 0.104
E12.2 With renal complications
0.000 0.896 0.104
E12.1 With ketoacidosis
0.000 0.896 0.104
E12.0 With coma
0.000 0.896 0.104
E04.0 Non-toxic diffuse goitre
0.000 0.897 0.103
E83.4 Disorders of magnesium metabolism
0.000 0.897 0.103
E61 Deficiency of other nutrient elements
0.000 0.897 0.103
E10 Insulin-dependent diabetes mellitus
0.000 0.898 0.102
E29.1 Testicular hypofunction
0.000 0.898 0.102
E27.2 Addisonian crisis
0.000 0.899 0.101
E73.8 Other lactose intolerance
0.000 0.899 0.101
E73.1 Secondary lactase deficiency
0.000 0.899 0.101
E73.0 Congenital lactase deficiency
0.000 0.899 0.101
E53.8 Deficiency of other specified B group vitamins
0.000 0.899 0.101
E07 Other disorders of thyroid
0.000 0.901 0.099
R79.8 Other specified abnormal findings of blood chemistry
0.000 0.902 0.098
S64 Injury of nerves at wrist and hand level
0.000 0.903 0.097
S61.7 Multiple open wounds of wrist and hand
0.000 0.904 0.096
S61.8 Open wound of other parts of wrist and hand
0.000 0.905 0.095
S66 Injury of muscle and tendon at wrist and hand level
0.000 0.905 0.095
E73.9 Lactose intolerance, unspecified
0.000 0.906 0.094
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.906 0.093
E45 Retarded development following protein-energy malnutrition
0.000 0.906 0.093
E43 Unspecified severe protein-energy malnutrition
0.000 0.906 0.093
E42 Marasmic kwashiorkor
0.000 0.906 0.093
E41 Nutritional marasmus
0.000 0.906 0.093
E40 Kwashiorkor
0.000 0.906 0.093
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.907 0.093
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.907 0.093
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.907 0.093
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.907 0.093
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.907 0.093
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.907 0.093
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.907 0.093
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.907 0.093
E55.9 Vitamin D deficiency, unspecified
0.000 0.907 0.093
S68 Traumatic amputation of wrist and hand
0.000 0.907 0.093
S69 Other and unspecified injuries of wrist and hand
0.000 0.907 0.093
E27.1 Primary adrenocortical insufficiency
0.000 0.909 0.091
E11.9 Without complications
0.000 0.909 0.091
E85.8 Other amyloidosis
0.000 0.909 0.090
E85.3 Secondary systemic amyloidosis
0.000 0.909 0.090
E85.2 Heredofamilial amyloidosis, unspecified
0.000 0.909 0.090
E85.1 Neuropathic heredofamilial amyloidosis
0.000 0.909 0.090
E85.0 Nonneuropathic heredofamilial amyloidosis
0.000 0.909 0.090
S60 Superficial injury of wrist and hand
0.000 0.910 0.090
E86 Volume depletion
0.000 0.910 0.090
S61.9 Open wound of wrist and hand, part unspecified
0.000 0.911 0.089
E03 Other hypothyroidism
0.000 0.911 0.088
E53.1 Pyridoxine deficiency
0.000 0.912 0.088
E53.0 Riboflavin deficiency
0.000 0.912 0.088
E15 Nondiabetic hypoglycaemic coma
0.000 0.912 0.088
E10.1 With ketoacidosis
0.000 0.912 0.088
S65 Injury of blood vessels at wrist and hand level
0.000 0.914 0.086
E55.0 Rickets, active
0.000 0.914 0.086
E89.3 Postprocedural hypopituitarism
0.000 0.914 0.086
E04.1 Non-toxic single thyroid nodule
0.000 0.914 0.086
S67 Crushing injury of wrist and hand
0.000 0.915 0.085
S61.1 Open wound of finger(s) with damage to nail
0.000 0.915 0.085
E88.9 Metabolic disorder, unspecified
0.000 0.915 0.085
E88.8 Other specified metabolic disorders
0.000 0.915 0.085
E88.3 Tumour lysis syndrome
0.000 0.915 0.085
E88.2 Lipomatosis, not elsewhere classified
0.000 0.915 0.085
E88.1 Lipodystrophy, not elsewhere classified
0.000 0.915 0.085
S66.1 Injury of flexor muscle and tendon of other finger at wrist and hand level
0.000 0.915 0.085
E85.4 Organ-limited amyloidosis
0.000 0.915 0.085
E89.4 Postprocedural ovarian failure
0.000 0.915 0.085
S64.4 Injury of digital nerve of other finger
0.000 0.915 0.085
E67 Other hyperalimentation
0.000 0.915 0.084
E68 Sequelae of hyperalimentation
0.000 0.915 0.084
E53.9 Vitamin B deficiency, unspecified
0.000 0.916 0.084
S68.1 Traumatic amputation of other single finger (complete)(partial)
0.000 0.916 0.084
E65 Localised adiposity
0.000 0.918 0.082
S69.9 Unspecified injury of wrist and hand
0.000 0.918 0.082
E10.4 With neurological complications
0.000 0.918 0.082
E06 Thyroiditis
0.001 0.919 0.081
E80.7 Disorder of bilirubin metabolism, unspecified
0.000 0.919 0.081
E80.6 Other disorders of bilirubin metabolism
0.000 0.919 0.081
E80.5 Crigler-Najjar syndrome
0.000 0.919 0.081
E80.3 Defects of catalase and peroxydase
0.000 0.919 0.081
E80.2 Other porphyria
0.000 0.919 0.081
E80.1 Porphyria cutanea tarda
0.000 0.919 0.081
E80.0 Hereditary erythropoietic porphyria
0.000 0.919 0.081
E50.9 Vitamin A deficiency, unspecified
0.000 0.919 0.081
E50.8 Other manifestations of vitamin A deficiency
0.000 0.919 0.081
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.919 0.081
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.919 0.081
E50.5 Vitamin A deficiency with night blindness
0.000 0.919 0.081
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.919 0.081
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.919 0.081
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.919 0.081
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.919 0.081
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.919 0.081
E51.9 Thiamine deficiency, unspecified
0.000 0.919 0.081
E51.8 Other manifestations of thiamine deficiency
0.000 0.919 0.081
E51.2 Wernicke's encephalopathy
0.000 0.919 0.081
E51.1 Beriberi
0.000 0.919 0.081
E56.9 Vitamin deficiency, unspecified
0.000 0.919 0.081
E56.8 Deficiency of other vitamins
0.000 0.919 0.081
E56.1 Deficiency of vitamin K
0.000 0.919 0.081
E56.0 Deficiency of vitamin E
0.000 0.919 0.081
E63.9 Nutritional deficiency, unspecified
0.000 0.919 0.081
E63.8 Other specified nutritional deficiencies
0.000 0.919 0.081
E63.1 Imbalance of constituents of food intake
0.000 0.919 0.081
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.919 0.081
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.919 0.081
E64.8 Sequelae of other nutritional deficiencies
0.000 0.919 0.081
E64.3 Sequelae of rickets
0.000 0.919 0.081
E64.2 Sequelae of vitamin C deficiency
0.000 0.919 0.081
E64.1 Sequelae of vitamin A deficiency
0.000 0.919 0.081
E64.0 Sequelae of protein-energy malnutrition
0.000 0.919 0.081
S62 Fracture at wrist and hand level
0.000 0.919 0.081
S62.60 Fracture of other finger (closed)
0.000 0.920 0.080
S62.6 Fracture of other finger
0.000 0.920 0.080
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.000 0.921 0.079
S64.1 Injury of median nerve at wrist and hand level
0.000 0.922 0.078
S64.0 Injury of ulnar nerve at wrist and hand level
0.000 0.923 0.077
E10.8 With unspecified complications
0.000 0.923 0.077
E04.9 Non-toxic goitre, unspecified
0.000 0.923 0.077
E85.9 Amyloidosis, unspecified
0.000 0.923 0.076
E28.9 Ovarian dysfunction, unspecified
0.000 0.924 0.076
E28.8 Other ovarian dysfunction
0.000 0.924 0.076
E28.1 Androgen excess
0.000 0.924 0.076
E28.0 Oestrogen excess
0.000 0.924 0.076
S60.9 Superficial injury of wrist and hand, unspecified
0.000 0.924 0.076
E46 Unspecified protein-energy malnutrition
0.000 0.925 0.075
S66.0 Injury of long flexor muscle and tendon of thumb at wrist and hand level
0.000 0.925 0.075
S67.0 Crushing injury of thumb and other finger(s)
0.000 0.925 0.074
E07.8 Other specified disorders of thyroid
0.000 0.926 0.074
E61.9 Deficiency of nutrient element, unspecified
0.000 0.926 0.074
E61.8 Deficiency of other specified nutrient elements
0.000 0.926 0.074
E61.7 Deficiency of multiple nutrient elements
0.000 0.926 0.074
E61.6 Vanadium deficiency
0.000 0.926 0.074
E61.5 Molybdenum deficiency
0.000 0.926 0.074
E61.4 Chromium deficiency
0.000 0.926 0.074
E61.3 Manganese deficiency
0.000 0.926 0.074
E61.2 Magnesium deficiency
0.000 0.926 0.074
E61.0 Copper deficiency
0.000 0.926 0.074
E10.7 With multiple complications
0.000 0.926 0.074
E10.6 With other specified complications
0.000 0.926 0.074
E10.0 With coma
0.000 0.926 0.074
E10.3 With ophthalmic complications
0.000 0.926 0.074
S66.7 Injury of multiple extensor muscles and tendons at wrist and hand level
0.000 0.927 0.073
S66.6 Injury of multiple flexor muscles and tendons at wrist and hand level
0.000 0.927 0.073
E28.3 Primary ovarian failure
0.000 0.928 0.071
E07.1 Dyshormogenetic goitre
0.000 0.929 0.071
E07.0 Hypersecretion of calcitonin
0.000 0.929 0.071
S65.5 Injury of blood vessel(s) of other finger
0.000 0.929 0.071
E03.8 Other specified hypothyroidism
0.000 0.929 0.070
E14 Unspecified diabetes mellitus
0.000 0.929 0.070
S64.9 Injury of unspecified nerve at wrist and hand level
0.000 0.930 0.070
S64.8 Injury of other nerves at wrist and hand level
0.000 0.930 0.070
S64.7 Injury of multiple nerves at wrist and hand level
0.000 0.930 0.070
S66.8 Injury of other muscles and tendons at wrist and hand level
0.000 0.931 0.069
S60.8 Other superficial injuries of wrist and hand
0.000 0.931 0.069
S66.5 Injury of intrinsic muscle and tendon of other finger at wrist and hand level
0.000 0.931 0.068
S66.4 Injury of intrinsic muscle and tendon of thumb at wrist and hand level
0.000 0.931 0.068
S64.3 Injury of digital nerve of thumb
0.000 0.932 0.068
E44.1 Mild protein-energy malnutrition
0.000 0.933 0.067
E44.0 Moderate protein-energy malnutrition
0.000 0.933 0.067
S68.9 Traumatic amputation of wrist and hand, level unspecified
0.000 0.933 0.067
S68.8 Traumatic amputation of other parts of wrist and hand
0.000 0.933 0.067
S68.4 Traumatic amputation of hand at wrist level
0.000 0.933 0.067
S68.3 Combined traumatic amputation of (part of) finger(s) with other parts of wrist and hand
0.000 0.933 0.067
S69.8 Other specified injuries of wrist and hand
0.000 0.933 0.067
S69.7 Multiple injuries of wrist and hand
0.000 0.933 0.067
S66.2 Injury of extensor muscle and tendon of thumb at wrist and hand level
0.000 0.933 0.067
S68.0 Traumatic amputation of thumb (complete)(partial)
0.000 0.934 0.066
S63.6 Sprain and strain of finger(s)
0.000 0.935 0.065
S60.0 Contusion of finger(s) without damage to nail
0.000 0.935 0.065
S64.2 Injury of radial nerve at wrist and hand level
0.000 0.935 0.065
S60.7 Multiple superficial injuries of wrist and hand
0.000 0.935 0.064
S60.1 Contusion of finger(s) with damage to nail
0.000 0.935 0.064
E10.5 With peripheral circulatory complications
0.000 0.935 0.064
S66.9 Injury of unspecified muscle and tendon at wrist and hand level
0.000 0.936 0.064
S62.3 Fracture of other metacarpal bone
0.000 0.936 0.064
E03.5 Myxoedema coma
0.000 0.936 0.064
E03.4 Atrophy of thyroid (acquired)
0.000 0.936 0.064
E03.3 Postinfectious hypothyroidism
0.000 0.936 0.064
E03.1 Congenital hypothyroidism without goitre
0.000 0.936 0.064
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.936 0.064
E61.1 Iron deficiency
0.000 0.936 0.063
S68.2 Traumatic amputation of two or more fingers alone (complete)(partial)
0.000 0.937 0.062
S65.9 Injury of unspecified blood vessel at wrist and hand level
0.000 0.938 0.062
S65.8 Injury of other blood vessels at wrist and hand level
0.000 0.938 0.062
S65.7 Injury of multiple blood vessels at wrist and hand level
0.000 0.938 0.062
S65.4 Injury of blood vessel(s) of thumb
0.000 0.938 0.062
S65.3 Injury of deep palmar arch
0.000 0.938 0.062
S65.2 Injury of superficial palmar arch
0.000 0.938 0.062
S65.1 Injury of radial artery at wrist and hand level
0.000 0.938 0.062
S65.0 Injury of ulnar artery at wrist and hand level
0.000 0.938 0.062
E87.6 Hypokalaemia
0.000 0.939 0.061

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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