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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs4959053
log Bayes Factor = 9.7873
Chromosome 6   position 31,099,577  (GRCh37) Explore rs4959053 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
M45.X9 Ankylosing spondylitis (Site unspecified)
1.000 0.000 0.000
E03.9 Hypothyroidism, unspecified
0.000 0.007 0.993
K90.0 Coeliac disease
0.000 0.014 0.986
M45 Ankylosing spondylitis
0.979 0.021 0.000
E03 Other hypothyroidism
0.000 0.033 0.967
E00-E07 Disorders of thyroid gland
0.000 0.044 0.956
M45.X0 Ankylosing spondylitis (Multiple sites in spine)
0.953 0.047 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.062 0.938
E10 Insulin-dependent diabetes mellitus
0.000 0.114 0.886
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.121 0.879
E05.9 Thyrotoxicosis, unspecified
0.000 0.122 0.878
E10-E14 Diabetes mellitus
0.000 0.124 0.876
E10.1 With ketoacidosis
0.000 0.129 0.871
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.135 0.865
E10.3 With ophthalmic complications
0.000 0.142 0.858
M45.X2 Ankylosing spondylitis (Cervical region)
0.831 0.169 0.000
E10.9 Without complications
0.000 0.206 0.794
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.252 0.748
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.274 0.726
E04 Other non-toxic goitre
0.000 0.288 0.712
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)
0.702 0.298 0.000
M45.X7 Ankylosing spondylitis (Lumbosacral region)
0.702 0.298 0.000
M45.X6 Ankylosing spondylitis (Lumbar region)
0.702 0.298 0.000
M45.X5 Ankylosing spondylitis (Thoracolumbar region)
0.702 0.298 0.000
M45.X4 Ankylosing spondylitis (Thoracic region)
0.702 0.298 0.000
M45.X3 Ankylosing spondylitis (Cervicothoracic region)
0.702 0.298 0.000
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)
0.702 0.298 0.000
E06 Thyroiditis
0.000 0.302 0.698
E10.2 With renal complications
0.000 0.306 0.694
E03.5 Myxoedema coma
0.000 0.306 0.693
E03.4 Atrophy of thyroid (acquired)
0.000 0.306 0.693
E03.3 Postinfectious hypothyroidism
0.000 0.306 0.693
E03.1 Congenital hypothyroidism without goitre
0.000 0.306 0.693
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.306 0.693
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.314 0.686
E00 Congenital iodine-deficiency syndrome
0.000 0.314 0.686
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.314 0.686
E20-E35 Disorders of other endocrine glands
0.000 0.315 0.685
E10.4 With neurological complications
0.000 0.316 0.684
E05.8 Other thyrotoxicosis
0.000 0.327 0.672
E05.5 Thyroid crisis or storm
0.000 0.327 0.672
E05.4 Thyrotoxicosis factitia
0.000 0.327 0.672
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.327 0.672
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.327 0.672
M45-M49 Spondylopathies
0.668 0.332 0.000
E40-E46 Malnutrition
0.000 0.343 0.657
E16 Other disorders of pancreatic internal secretion
0.000 0.346 0.654
E03.8 Other specified hypothyroidism
0.000 0.353 0.647
E10.8 With unspecified complications
0.000 0.365 0.635
E10.7 With multiple complications
0.000 0.365 0.635
E10.6 With other specified complications
0.000 0.365 0.635
E10.5 With peripheral circulatory complications
0.000 0.365 0.635
E10.0 With coma
0.000 0.365 0.635
E12 Malnutrition-related diabetes mellitus
0.000 0.372 0.628
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.377 0.623
E13 Other specified diabetes mellitus
0.000 0.394 0.606
E16.2 Hypoglycaemia, unspecified
0.000 0.396 0.604
E04.9 Non-toxic goitre, unspecified
0.000 0.400 0.600
E27 Other disorders of adrenal gland
0.000 0.402 0.598
E21.0 Primary hyperparathyroidism
0.000 0.419 0.581
M46 Other inflammatory spondylopathies
0.576 0.424 0.000
M48 Other spondylopathies
0.574 0.426 0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.430 0.570
E27.1 Primary adrenocortical insufficiency
0.000 0.448 0.552
E15 Nondiabetic hypoglycaemic coma
0.000 0.463 0.536
E24 Cushing's syndrome
0.000 0.466 0.534
E06.3 Autoimmune thyroiditis
0.000 0.487 0.512
E04.8 Other specified non-toxic goitre
0.000 0.489 0.511
E04.0 Non-toxic diffuse goitre
0.000 0.489 0.511
M46.9 Inflammatory spondylopathy, unspecified
0.510 0.490 0.000
E06.9 Thyroiditis, unspecified
0.000 0.500 0.500
E06.5 Other chronic thyroiditis
0.000 0.500 0.500
E06.4 Drug-induced thyroiditis
0.000 0.500 0.500
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.500 0.500
E06.1 Subacute thyroiditis
0.000 0.500 0.500
E06.0 Acute thyroiditis
0.000 0.500 0.500
M48.0 Spinal stenosis
0.499 0.501 0.000
E46 Unspecified protein-energy malnutrition
0.000 0.502 0.498
E14 Unspecified diabetes mellitus
0.000 0.506 0.494
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.508 0.492
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.508 0.492
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.508 0.492
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.508 0.492
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.508 0.492
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.508 0.492
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.508 0.492
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.508 0.492
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.509 0.491
E32 Diseases of thymus
0.000 0.509 0.491
E31 Polyglandular dysfunction
0.000 0.509 0.491
E30 Disorders of puberty, not elsewhere classified
0.000 0.509 0.491
E25 Adrenogenital disorders
0.000 0.509 0.491
E20 Hypoparathyroidism
0.000 0.509 0.491
E04.1 Non-toxic single thyroid nodule
0.000 0.510 0.490
M48.02 Spinal stenosis (Cervical region)
0.490 0.510 0.000
E07 Other disorders of thyroid
0.000 0.513 0.487
M49 Spondylopathies in diseases classified elsewhere
0.479 0.521 0.000
E26 Hyperaldosteronism
0.000 0.521 0.479
E65-E68 Obesity and other hyperalimentation
0.000 0.527 0.473
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.529 0.471
E45 Retarded development following protein-energy malnutrition
0.000 0.529 0.471
E43 Unspecified severe protein-energy malnutrition
0.000 0.529 0.471
E42 Marasmic kwashiorkor
0.000 0.529 0.471
E41 Nutritional marasmus
0.000 0.529 0.471
E40 Kwashiorkor
0.000 0.529 0.471
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.531 0.469
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.531 0.469
E16.4 Abnormal secretion of gastrin
0.000 0.531 0.469
E16.3 Increased secretion of glucagon
0.000 0.531 0.469
E16.1 Other hypoglycaemia
0.000 0.531 0.469
E34 Other endocrine disorders
0.000 0.536 0.464
E12.9 Without complications
0.000 0.550 0.450
E12.8 With unspecified complications
0.000 0.550 0.450
E12.7 With multiple complications
0.000 0.550 0.450
E12.6 With other specified complications
0.000 0.550 0.450
E12.5 With peripheral circulatory complications
0.000 0.550 0.450
E12.4 With neurological complications
0.000 0.550 0.450
E12.3 With ophthalmic complications
0.000 0.550 0.450
E12.2 With renal complications
0.000 0.550 0.450
E12.1 With ketoacidosis
0.000 0.550 0.450
E12.0 With coma
0.000 0.550 0.450
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.553 0.446
E21.4 Other specified disorders of parathyroid gland
0.000 0.553 0.446
E21.2 Other hyperparathyroidism
0.000 0.553 0.446
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.553 0.446
E22 Hyperfunction of pituitary gland
0.000 0.556 0.444
E13.8 With unspecified complications
0.000 0.565 0.435
E13.7 With multiple complications
0.000 0.565 0.435
E13.6 With other specified complications
0.000 0.565 0.435
E13.5 With peripheral circulatory complications
0.000 0.565 0.435
E13.4 With neurological complications
0.000 0.565 0.435
E13.3 With ophthalmic complications
0.000 0.565 0.435
E13.2 With renal complications
0.000 0.565 0.435
E13.1 With ketoacidosis
0.000 0.565 0.435
E13.0 With coma
0.000 0.565 0.435
E21.3 Hyperparathyroidism, unspecified
0.000 0.565 0.434
E50-E64 Other nutritional deficiencies
0.000 0.567 0.433
M46.90 Inflammatory spondylopathy, unspecified (Multiple sites in spine)
0.429 0.571 0.000
E27.5 Adrenomedullary hyperfunction
0.000 0.571 0.428
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.571 0.428
E27.2 Addisonian crisis
0.000 0.571 0.428
E27.0 Other adrenocortical overactivity
0.000 0.571 0.428
M48.5 Collapsed vertebra, not elsewhere classified
0.428 0.572 0.000
E04.2 Non-toxic multinodular goitre
0.000 0.572 0.428
E24.9 Cushing's syndrome, unspecified
0.000 0.574 0.426
M46.99 Inflammatory spondylopathy, unspecified (Site unspecified)
0.418 0.582 0.000
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.586 0.414
E13.9 Without complications
0.000 0.587 0.413
M46.8 Other specified inflammatory spondylopathies
0.413 0.587 0.000
M46.5 Other infective spondylopathies
0.413 0.587 0.000
M46.3 Infection of intervertebral disk (pyogenic)
0.413 0.587 0.000
M46.2 Osteomyelitis of vertebra
0.413 0.587 0.000
M46.1 Sacro-iliitis, not elsewhere classified
0.413 0.587 0.000
M46.0 Spinal enthesopathy
0.413 0.587 0.000
M46.4 Discitis, unspecified
0.413 0.587 0.000
E29 Testicular dysfunction
0.000 0.587 0.412
E27.9 Disorder of adrenal gland, unspecified
0.000 0.588 0.412
M48.9 Spondylopathy, unspecified
0.412 0.588 0.000
M48.8 Other specified spondylopathies
0.412 0.588 0.000
M48.4 Fatigue fracture of vertebra
0.412 0.588 0.000
M48.3 Traumatic spondylopathy
0.412 0.588 0.000
M48.2 Kissing spine
0.412 0.588 0.000
M48.1 Ankylosing hyperostosis [Forestier]
0.412 0.588 0.000
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.590 0.410
E27.8 Other specified disorders of adrenal gland
0.000 0.596 0.403
E14.3 With ophthalmic complications
0.000 0.597 0.403
M48.04 Spinal stenosis (Thoracic region)
0.397 0.603 0.000
E24.8 Other Cushing's syndrome
0.000 0.617 0.383
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.617 0.383
E24.3 Ectopic ACTH syndrome
0.000 0.617 0.383
E24.2 Drug-induced Cushing's syndrome
0.000 0.617 0.383
E24.1 Nelson's syndrome
0.000 0.617 0.383
E24.0 Pituitary-dependent Cushing's disease
0.000 0.617 0.383
K90 Intestinal malabsorption
0.000 0.619 0.381
M46.96 Inflammatory spondylopathy, unspecified (Lumbar region)
0.379 0.621 0.000
E23 Hypofunction and other disorders of pituitary gland
0.000 0.629 0.370
E34.9 Endocrine disorder, unspecified
0.000 0.634 0.366
M46.98 Inflammatory spondylopathy, unspecified (Sacral and sacrococcygeal region)
0.366 0.634 0.000
M46.97 Inflammatory spondylopathy, unspecified (Lumbosacral region)
0.366 0.634 0.000
M46.95 Inflammatory spondylopathy, unspecified (Thoracolumbar region)
0.366 0.634 0.000
M46.94 Inflammatory spondylopathy, unspecified (Thoracic region)
0.366 0.634 0.000
M46.93 Inflammatory spondylopathy, unspecified (Cervicothoracic region)
0.366 0.634 0.000
M46.91 Inflammatory spondylopathy, unspecified (Occipito-atlanto-axial region)
0.366 0.634 0.000
M46.92 Inflammatory spondylopathy, unspecified (Cervical region)
0.366 0.634 0.000
M48.08 Spinal stenosis (Sacral and sacrococcygeal region)
0.358 0.642 0.000
M48.05 Spinal stenosis (Thoracolumbar region)
0.358 0.642 0.000
M48.03 Spinal stenosis (Cervicothoracic region)
0.358 0.642 0.000
M48.01 Spinal stenosis (Occipito-atlanto-axial region)
0.358 0.642 0.000
E14.8 With unspecified complications
0.000 0.646 0.354
E14.7 With multiple complications
0.000 0.646 0.354
E14.6 With other specified complications
0.000 0.646 0.354
E14.5 With peripheral circulatory complications
0.000 0.646 0.354
E14.4 With neurological complications
0.000 0.646 0.354
E14.2 Withrenal complications
0.000 0.646 0.354
E14.1 With ketoacidosis
0.000 0.646 0.354
E14.0 With coma
0.000 0.646 0.354
E20.9 Hypoparathyroidism, unspecified
0.000 0.648 0.352
E20.8 Other hypoparathyroidism
0.000 0.648 0.352
E20.1 Pseudohypoparathyroidism
0.000 0.648 0.352
E20.0 Idiopathic hypoparathyroidism
0.000 0.648 0.352
E25.9 Adrenogenital disorder, unspecified
0.000 0.648 0.352
E25.8 Other adrenogenital disorders
0.000 0.648 0.352
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.648 0.352
E30.9 Disorder of puberty, unspecified
0.000 0.648 0.352
E30.8 Other disorders of puberty
0.000 0.648 0.352
E30.1 Precocious puberty
0.000 0.648 0.352
E30.0 Delayed puberty
0.000 0.648 0.352
E31.9 Polyglandular dysfunction, unspecified
0.000 0.648 0.352
E31.8 Other polyglandular dysfunction
0.000 0.648 0.352
E31.1 Polyglandular hyperfunction
0.000 0.648 0.352
E31.0 Autoimmune polyglandular failure
0.000 0.648 0.352
E32.9 Disease of thymus, unspecified
0.000 0.648 0.352
E32.8 Other diseases of thymus
0.000 0.648 0.352
E32.1 Abscess of thymus
0.000 0.648 0.352
E32.0 Persistent hyperplasia of thymus
0.000 0.648 0.352
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.648 0.352
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.648 0.352
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.648 0.352
E07.1 Dyshormogenetic goitre
0.000 0.651 0.349
E07.0 Hypersecretion of calcitonin
0.000 0.651 0.349
M49.8 Spondylopathy in other diseases classified elsewhere
0.344 0.656 0.000
M49.5 Collapsed vertebra in diseases classified elsewhere
0.344 0.656 0.000
M49.4 Neuropathic spondylopathy
0.344 0.656 0.000
M49.3 Spondylopathy in other infectious and parasitic diseases classified elsewhere
0.344 0.656 0.000
M49.2 Enterobacterial spondylitis
0.344 0.656 0.000
M49.1 Brucella spondylitis
0.344 0.656 0.000
M49.0 Tuberculosis of spine
0.344 0.656 0.000
E26.9 Hyperaldosteronism, unspecified
0.000 0.656 0.343
E26.8 Other hyperaldosteronism
0.000 0.656 0.343
E26.1 Secondary hyperaldosteronism
0.000 0.656 0.343
E67 Other hyperalimentation
0.000 0.661 0.339
E68 Sequelae of hyperalimentation
0.000 0.661 0.339
E44.1 Mild protein-energy malnutrition
0.000 0.662 0.338
E44.0 Moderate protein-energy malnutrition
0.000 0.662 0.338
M48.00 Spinal stenosis (Multiple sites in spine)
0.336 0.664 0.000
E34.5 Androgen resistance syndrome
0.000 0.667 0.332
E34.4 Constitutional tall stature
0.000 0.667 0.332
E34.3 Short stature, not elsewhere classified
0.000 0.667 0.332
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.667 0.332
E34.1 Other hypersecretion of intestinal hormones
0.000 0.667 0.332
E34.0 Carcinoid syndrome
0.000 0.667 0.332
E26.0 Primary hyperaldosteronism
0.000 0.669 0.331
M48.09 Spinal stenosis (Site unspecified)
0.330 0.670 0.000
E65 Localised adiposity
0.000 0.670 0.329
M47 Spondylosis
0.327 0.673 0.000
E28 Ovarian dysfunction
0.001 0.676 0.323
M48.54 Collapsed vertebra, not elsewhere classified (Thoracic region)
0.323 0.677 0.000
E22.1 Hyperprolactinaemia
0.000 0.680 0.320
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.681 0.318
E22.8 Other hyperfunction of pituitary gland
0.000 0.681 0.318
E07.8 Other specified disorders of thyroid
0.000 0.683 0.316
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.687 0.313
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.689 0.310
E63 Other nutritional deficiencies
0.000 0.689 0.310
E56 Other vitamin deficiencies
0.000 0.689 0.310
E51 Thiamine deficiency
0.000 0.689 0.310
E50 Vitamin A deficiency
0.000 0.689 0.310
E60 Dietary zinc deficiency
0.000 0.689 0.310
E59 Dietary selenium deficiency
0.000 0.689 0.310
E58 Dietary calcium deficiency
0.000 0.689 0.310
E54 Ascorbic acid deficiency
0.000 0.689 0.310
E52 Niacin deficiency [pellagra]
0.000 0.689 0.310
M48.56 Collapsed vertebra, not elsewhere classified (Lumbar region)
0.309 0.691 0.000
M48.59 Collapsed vertebra, not elsewhere classified (Site unspecified)
0.307 0.693 0.000
M48.58 Collapsed vertebra, not elsewhere classified (Sacral and sacrococcygeal region)
0.307 0.693 0.000
M48.57 Collapsed vertebra, not elsewhere classified (Lumbosacral region)
0.307 0.693 0.000
M48.55 Collapsed vertebra, not elsewhere classified (Thoracolumbar region)
0.307 0.693 0.000
M48.53 Collapsed vertebra, not elsewhere classified (Cervicothoracic region)
0.307 0.693 0.000
M48.52 Collapsed vertebra, not elsewhere classified (Cervical region)
0.307 0.693 0.000
M48.51 Collapsed vertebra, not elsewhere classified (Occipito-atlanto-axial region)
0.307 0.693 0.000
M48.50 Collapsed vertebra, not elsewhere classified (Multiple sites in spine)
0.307 0.693 0.000
M46.09 Spinal enthesopathy (Site unspecified)
0.296 0.704 0.000
M46.08 Spinal enthesopathy (Sacral and sacrococcygeal region)
0.296 0.704 0.000
M46.07 Spinal enthesopathy (Lumbosacral region)
0.296 0.704 0.000
M46.06 Spinal enthesopathy (Lumbar region)
0.296 0.704 0.000
M46.05 Spinal enthesopathy (Thoracolumbar region)
0.296 0.704 0.000
M46.04 Spinal enthesopathy (Thoracic region)
0.296 0.704 0.000
M46.03 Spinal enthesopathy (Cervicothoracic region)
0.296 0.704 0.000
M46.02 Spinal enthesopathy (Cervical region)
0.296 0.704 0.000
M46.01 Spinal enthesopathy (Occipito-atlanto-axial region)
0.296 0.704 0.000
M46.00 Spinal enthesopathy (Multiple sites in spine)
0.296 0.704 0.000
M46.19 Sacroiliitis, not elsewhere classified-Site unspe
0.296 0.704 0.000
M46.18 Sacroiliitis, not elsewhere classified-Sacral/sacrococ
0.296 0.704 0.000
M46.17 Sacroiliitis, not elsewhere classified-Lumbosacral
0.296 0.704 0.000
M46.16 Sacroiliitis, not elsewhere classified-Lumbar
0.296 0.704 0.000
M46.15 Sacroiliitis, not elsewhere classified-Thoracolumbar
0.296 0.704 0.000
M46.14 Sacroiliitis, not elsewhere classified-Thoracic
0.296 0.704 0.000
M46.13 Sacroiliitis, not elsewhere classified-Cervicothoracic
0.296 0.704 0.000
M46.12 Sacroiliitis, not elsewhere classified-Cervical
0.296 0.704 0.000
M46.11 Sacroiliitis, not elsewhere classified-Occipit-atl-axl
0.296 0.704 0.000
M46.10 Sacroiliitis, not elsewhere classified-Mult site
0.296 0.704 0.000
M46.29 Osteomyelitis of vertebra (Site unspecified)
0.296 0.704 0.000
M46.28 Osteomyelitis of vertebra (Sacral and sacrococcygeal region)
0.296 0.704 0.000
M46.27 Osteomyelitis of vertebra (Lumbosacral region)
0.296 0.704 0.000
M46.26 Osteomyelitis of vertebra (Lumbar region)
0.296 0.704 0.000
M46.25 Osteomyelitis of vertebra (Thoracolumbar region)
0.296 0.704 0.000
M46.24 Osteomyelitis of vertebra (Thoracic region)
0.296 0.704 0.000
M46.23 Osteomyelitis of vertebra (Cervicothoracic region)
0.296 0.704 0.000
M46.22 Osteomyelitis of vertebra (Cervical region)
0.296 0.704 0.000
M46.21 Osteomyelitis of vertebra (Occipito-atlanto-axial region)
0.296 0.704 0.000
M46.20 Osteomyelitis of vertebra (Multiple sites in spine)
0.296 0.704 0.000
M46.39 Infection of intervertebral disc (pyogenic) (Site unspecified)
0.296 0.704 0.000
M46.38 Infection of intervertebral disc (pyogenic) (Sacral and sacrococcygeal region)
0.296 0.704 0.000
M46.37 Infection of intervertebral disc (pyogenic) (Lumbosacral region)
0.296 0.704 0.000
M46.36 Infection of intervertebral disc (pyogenic) (Lumbar region)
0.296 0.704 0.000
M46.35 Infection of intervertebral disc (pyogenic) (Thoracolumbar region)
0.296 0.704 0.000
M46.34 Infection of intervertebral disc (pyogenic) (Thoracic region)
0.296 0.704 0.000
M46.33 Infection of intervertebral disc (pyogenic) (Cervicothoracic region)
0.296 0.704 0.000
M46.32 Infection of intervertebral disc (pyogenic) (Cervical region)
0.296 0.704 0.000
M46.31 Infection of intervertebral disc (pyogenic) (Occipito-atlanto-axial region)
0.296 0.704 0.000
M46.30 Infection of intervertebral disc (pyogenic) (Multiple sites in spine)
0.296 0.704 0.000
M46.59 Other infective spondylopathies (Site unspecified)
0.296 0.704 0.000
M46.58 Other infective spondylopathies (Sacral and sacrococcygeal region)
0.296 0.704 0.000
M46.57 Other infective spondylopathies (Lumbosacral region)
0.296 0.704 0.000
M46.56 Other infective spondylopathies (Lumbar region)
0.296 0.704 0.000
M46.55 Other infective spondylopathies (Thoracolumbar region)
0.296 0.704 0.000
M46.54 Other infective spondylopathies (Thoracic region)
0.296 0.704 0.000
M46.53 Other infective spondylopathies (Cervicothoracic region)
0.296 0.704 0.000
M46.52 Other infective spondylopathies (Cervical region)
0.296 0.704 0.000
M46.51 Other infective spondylopathies (Occipito-atlanto-axial region)
0.296 0.704 0.000
M46.50 Other infective spondylopathies (Multiple sites in spine)
0.296 0.704 0.000
M46.89 Other specified inflammatory spondylopathies (Site unspecified)
0.296 0.704 0.000
M46.88 Other specified inflammatory spondylopathies (Sacral and sacrococcygeal region)
0.296 0.704 0.000
M46.87 Other specified inflammatory spondylopathies (Lumbosacral region)
0.296 0.704 0.000
M46.86 Other specified inflammatory spondylopathies (Lumbar region)
0.296 0.704 0.000
M46.85 Other specified inflammatory spondylopathies (Thoracolumbar region)
0.296 0.704 0.000
M46.84 Other specified inflammatory spondylopathies (Thoracic region)
0.296 0.704 0.000
M46.83 Other specified inflammatory spondylopathies (Cervicothoracic region)
0.296 0.704 0.000
M46.82 Other specified inflammatory spondylopathies (Cervical region)
0.296 0.704 0.000
M46.81 Other specified inflammatory spondylopathies (Occipito-atlanto-axial region)
0.296 0.704 0.000
M46.80 Other specified inflammatory spondylopathies (Multiple sites in spine)
0.296 0.704 0.000
M46.49 Discitis, unspecified (Site unspecified)
0.296 0.704 0.000
M46.48 Discitis, unspecified (Sacral and sacrococcygeal region)
0.296 0.704 0.000
M46.47 Discitis, unspecified (Lumbosacral region)
0.296 0.704 0.000
M46.45 Discitis, unspecified (Thoracolumbar region)
0.296 0.704 0.000
M46.44 Discitis, unspecified (Thoracic region)
0.296 0.704 0.000
M46.43 Discitis, unspecified (Cervicothoracic region)
0.296 0.704 0.000
M46.42 Discitis, unspecified (Cervical region)
0.296 0.704 0.000
M46.41 Discitis, unspecified (Occipito-atlanto-axial region)
0.296 0.704 0.000
M46.40 Discitis, unspecified (Multiple sites in spine)
0.296 0.704 0.000
E29.9 Testicular dysfunction, unspecified
0.000 0.704 0.296
E29.8 Other testicular dysfunction
0.000 0.704 0.296
E29.0 Testicular hyperfunction
0.000 0.704 0.296
M46.46 Discitis, unspecified (Lumbar region)
0.296 0.704 0.000
M48.19 Ankylosing hyperostosis [Forestier] (Site unspecified)
0.295 0.705 0.000
M48.18 Ankylosing hyperostosis [Forestier] (Sacral and sacrococcygeal region)
0.295 0.705 0.000
M48.17 Ankylosing hyperostosis [Forestier] (Lumbosacral region)
0.295 0.705 0.000
M48.16 Ankylosing hyperostosis [Forestier] (Lumbar region)
0.295 0.705 0.000
M48.15 Ankylosing hyperostosis [Forestier] (Thoracolumbar region)
0.295 0.705 0.000
M48.14 Ankylosing hyperostosis [Forestier] (Thoracic region)
0.295 0.705 0.000
M48.13 Ankylosing hyperostosis [Forestier] (Cervicothoracic region)
0.295 0.705 0.000
M48.12 Ankylosing hyperostosis [Forestier] (Cervical region)
0.295 0.705 0.000
M48.11 Ankylosing hyperostosis [Forestier] (Occipito-atlanto-axial region)
0.295 0.705 0.000
M48.10 Ankylosing hyperostosis [Forestier] (Multiple sites in spine)
0.295 0.705 0.000
M48.29 Kissing spine (Site unspecified)
0.295 0.705 0.000
M48.28 Kissing spine (Sacral and sacrococcygeal region)
0.295 0.705 0.000
M48.27 Kissing spine (Lumbosacral region)
0.295 0.705 0.000
M48.26 Kissing spine (Lumbar region)
0.295 0.705 0.000
M48.25 Kissing spine (Thoracolumbar region)
0.295 0.705 0.000
M48.24 Kissing spine (Thoracic region)
0.295 0.705 0.000
M48.23 Kissing spine (Cervicothoracic region)
0.295 0.705 0.000
M48.22 Kissing spine (Cervical region)
0.295 0.705 0.000
M48.21 Kissing spine (Occipito-atlanto-axial region)
0.295 0.705 0.000
M48.20 Kissing spine (Multiple sites in spine)
0.295 0.705 0.000
M48.39 Traumatic spondylopathy (Site unspecified)
0.295 0.705 0.000
M48.38 Traumatic spondylopathy (Sacral and sacrococcygeal region)
0.295 0.705 0.000
M48.37 Traumatic spondylopathy (Lumbosacral region)
0.295 0.705 0.000
M48.36 Traumatic spondylopathy (Lumbar region)
0.295 0.705 0.000
M48.35 Traumatic spondylopathy (Thoracolumbar region)
0.295 0.705 0.000
M48.34 Traumatic spondylopathy (Thoracic region)
0.295 0.705 0.000
M48.33 Traumatic spondylopathy (Cervicothoracic region)
0.295 0.705 0.000
M48.32 Traumatic spondylopathy (Cervical region)
0.295 0.705 0.000
M48.31 Traumatic spondylopathy (Occipito-atlanto-axial region)
0.295 0.705 0.000
M48.30 Traumatic spondylopathy (Multiple sites in spine)
0.295 0.705 0.000
M48.49 Fatigue fracture of vertebra (Site unspecified)
0.295 0.705 0.000
M48.48 Fatigue fracture of vertebra (Sacral and sacrococcygeal region)
0.295 0.705 0.000
M48.47 Fatigue fracture of vertebra (Lumbosacral region)
0.295 0.705 0.000
M48.46 Fatigue fracture of vertebra (Lumbar region)
0.295 0.705 0.000
M48.45 Fatigue fracture of vertebra (Thoracolumbar region)
0.295 0.705 0.000
M48.44 Fatigue fracture of vertebra (Thoracic region)
0.295 0.705 0.000
M48.43 Fatigue fracture of vertebra (Cervicothoracic region)
0.295 0.705 0.000
M48.42 Fatigue fracture of vertebra (Cervical region)
0.295 0.705 0.000
M48.41 Fatigue fracture of vertebra (Occipito-atlanto-axial region)
0.295 0.705 0.000
M48.40 Fatigue fracture of vertebra (Multiple sites in spine)
0.295 0.705 0.000
M48.89 Other specified spondylopathies (Site unspecified)
0.295 0.705 0.000
M48.88 Other specified spondylopathies (Sacral and sacrococcygeal region)
0.295 0.705 0.000
M48.87 Other specified spondylopathies (Lumbosacral region)
0.295 0.705 0.000
M48.86 Other specified spondylopathies (Lumbar region)
0.295 0.705 0.000
M48.85 Other specified spondylopathies (Thoracolumbar region)
0.295 0.705 0.000
M48.84 Other specified spondylopathies (Thoracic region)
0.295 0.705 0.000
M48.83 Other specified spondylopathies (Cervicothoracic region)
0.295 0.705 0.000
M48.82 Other specified spondylopathies (Cervical region)
0.295 0.705 0.000
M48.81 Other specified spondylopathies (Occipito-atlanto-axial region)
0.295 0.705 0.000
M48.80 Other specified spondylopathies (Multiple sites in spine)
0.295 0.705 0.000
M48.99 Spondylopathy, unspecified (Site unspecified)
0.295 0.705 0.000
M48.98 Spondylopathy, unspecified (Sacral and sacrococcygeal region)
0.295 0.705 0.000
M48.97 Spondylopathy, unspecified (Lumbosacral region)
0.295 0.705 0.000
M48.96 Spondylopathy, unspecified (Lumbar region)
0.295 0.705 0.000
M48.95 Spondylopathy, unspecified (Thoracolumbar region)
0.295 0.705 0.000
M48.94 Spondylopathy, unspecified (Thoracic region)
0.295 0.705 0.000
M48.93 Spondylopathy, unspecified (Cervicothoracic region)
0.295 0.705 0.000
M48.92 Spondylopathy, unspecified (Cervical region)
0.295 0.705 0.000
M48.91 Spondylopathy, unspecified (Occipito-atlanto-axial region)
0.295 0.705 0.000
M48.90 Spondylopathy, unspecified (Multiple sites in spine)
0.295 0.705 0.000
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.712 0.288
E61 Deficiency of other nutrient elements
0.000 0.719 0.281
E23.2 Diabetes insipidus
0.000 0.723 0.277
E22.0 Acromegaly and pituitary gigantism
0.000 0.724 0.276
K90.3 Pancreatic steatorrhoea
0.000 0.727 0.273
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.727 0.273
K90.1 Tropical sprue
0.000 0.727 0.273
M48.07 Spinal stenosis (Lumbosacral region)
0.268 0.732 0.000
K90.9 Intestinal malabsorption, unspecified
0.000 0.732 0.267
E23.7 Disorder of pituitary gland, unspecified
0.000 0.734 0.266
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.734 0.266
E23.1 Drug-induced hypopituitarism
0.000 0.734 0.266
E55 Vitamin D deficiency
0.000 0.742 0.258
M47.2 Other spondylosis with radiculopathy
0.257 0.743 0.000
E53 Deficiency of other B group vitamins
0.000 0.748 0.252
E34.8 Other specified endocrine disorders
0.001 0.749 0.251
M49.09 Tuberculosis of spine (Site unspecified)
0.246 0.753 0.000
M49.08 Tuberculosis of spine (Sacral and sacrococcygeal region)
0.246 0.753 0.000
M49.07 Tuberculosis of spine (Lumbosacral region)
0.246 0.753 0.000
M49.06 Tuberculosis of spine (Lumbar region)
0.246 0.753 0.000
M49.05 Tuberculosis of spine (Thoracolumbar region)
0.246 0.753 0.000
M49.04 Tuberculosis of spine (Thoracic region)
0.246 0.753 0.000
M49.03 Tuberculosis of spine (Cervicothoracic region)
0.246 0.753 0.000
M49.02 Tuberculosis of spine (Cervical region)
0.246 0.753 0.000
M49.01 Tuberculosis of spine (Occipito-atlanto-axial region)
0.246 0.753 0.000
M49.00 Tuberculosis of spine (Multiple sites in spine)
0.246 0.753 0.000
M49.19 Brucella spondylitis (Site unspecified)
0.246 0.753 0.000
M49.18 Brucella spondylitis (Sacral and sacrococcygeal region)
0.246 0.753 0.000
M49.17 Brucella spondylitis (Lumbosacral region)
0.246 0.753 0.000
M49.16 Brucella spondylitis (Lumbar region)
0.246 0.753 0.000
M49.15 Brucella spondylitis (Thoracolumbar region)
0.246 0.753 0.000
M49.14 Brucella spondylitis (Thoracic region)
0.246 0.753 0.000
M49.13 Brucella spondylitis (Cervicothoracic region)
0.246 0.753 0.000
M49.12 Brucella spondylitis (Cervical region)
0.246 0.753 0.000
M49.11 Brucella spondylitis (Occipito-atlanto-axial region)
0.246 0.753 0.000
M49.10 Brucella spondylitis (Multiple sites in spine)
0.246 0.753 0.000
M49.29 Enterobacterial spondylitis (Site unspecified)
0.246 0.753 0.000
M49.28 Enterobacterial spondylitis (Sacral and sacrococcygeal region)
0.246 0.753 0.000
M49.27 Enterobacterial spondylitis (Lumbosacral region)
0.246 0.753 0.000
M49.26 Enterobacterial spondylitis (Lumbar region)
0.246 0.753 0.000
M49.25 Enterobacterial spondylitis (Thoracolumbar region)
0.246 0.753 0.000
M49.24 Enterobacterial spondylitis (Thoracic region)
0.246 0.753 0.000
M49.23 Enterobacterial spondylitis (Cervicothoracic region)
0.246 0.753 0.000
M49.22 Enterobacterial spondylitis (Cervical region)
0.246 0.753 0.000
M49.21 Enterobacterial spondylitis (Occipito-atlanto-axial region)
0.246 0.753 0.000
M49.20 Enterobacterial spondylitis (Multiple sites in spine)
0.246 0.753 0.000
M49.39 Spondylopathy in other infectious and parasitic diseases classified elsewhere (Site unspecified)
0.246 0.753 0.000
M49.38 Spondylopathy in other infectious and parasitic diseases classified elsewhere (Sacral and sacrococcygeal region)
0.246 0.753 0.000
M49.37 Spondylopathy in other infectious and parasitic diseases classified elsewhere (Lumbosacral region)
0.246 0.753 0.000
M49.36 Spondylopathy in other infectious and parasitic diseases classified elsewhere (Lumbar region)
0.246 0.753 0.000
M49.35 Spondylopathy in other infectious and parasitic diseases classified elsewhere (Thoracolumbar region)
0.246 0.753 0.000
M49.34 Spondylopathy in other infectious and parasitic diseases classified elsewhere (Thoracic region)
0.246 0.753 0.000
M49.33 Spondylopathy in other infectious and parasitic diseases classified elsewhere (Cervicothoracic region)
0.246 0.753 0.000
M49.32 Spondylopathy in other infectious and parasitic diseases classified elsewhere (Cervical region)
0.246 0.753 0.000
M49.31 Spondylopathy in other infectious and parasitic diseases classified elsewhere (Occipito-atlanto-axial region)
0.246 0.753 0.000
M49.30 Spondylopathy in other infectious and parasitic diseases classified elsewhere (Multiple sites in spine)
0.246 0.753 0.000
M49.49 Neuropathic spondylopathy (Site unspecified)
0.246 0.753 0.000
M49.48 Neuropathic spondylopathy (Sacral and sacrococcygeal region)
0.246 0.753 0.000
M49.47 Neuropathic spondylopathy (Lumbosacral region)
0.246 0.753 0.000
M49.46 Neuropathic spondylopathy (Lumbar region)
0.246 0.753 0.000
M49.45 Neuropathic spondylopathy (Thoracolumbar region)
0.246 0.753 0.000
M49.44 Neuropathic spondylopathy (Thoracic region)
0.246 0.753 0.000
M49.43 Neuropathic spondylopathy (Cervicothoracic region)
0.246 0.753 0.000
M49.42 Neuropathic spondylopathy (Cervical region)
0.246 0.753 0.000
M49.41 Neuropathic spondylopathy (Occipito-atlanto-axial region)
0.246 0.753 0.000
M49.40 Neuropathic spondylopathy (Multiple sites in spine)
0.246 0.753 0.000
M49.59 Collapsed vertebra in diseases classified elsewhere (Site unspecified)
0.246 0.753 0.000
M49.58 Collapsed vertebra in diseases classified elsewhere (Sacral and sacrococcygeal region)
0.246 0.753 0.000
M49.57 Collapsed vertebra in diseases classified elsewhere (Lumbosacral region)
0.246 0.753 0.000
M49.56 Collapsed vertebra in diseases classified elsewhere (Lumbar region)
0.246 0.753 0.000
M49.55 Collapsed vertebra in diseases classified elsewhere (Thoracolumbar region)
0.246 0.753 0.000
M49.54 Collapsed vertebra in diseases classified elsewhere (Thoracic region)
0.246 0.753 0.000
M49.53 Collapsed vertebra in diseases classified elsewhere (Cervicothoracic region)
0.246 0.753 0.000
M49.52 Collapsed vertebra in diseases classified elsewhere (Cervical region)
0.246 0.753 0.000
M49.51 Collapsed vertebra in diseases classified elsewhere (Occipito-atlanto-axial region)
0.246 0.753 0.000
M49.50 Collapsed vertebra in diseases classified elsewhere (Multiple sites in spine)
0.246 0.753 0.000
M49.89 Spondylopathy in other diseases classified elsewhere (Site unspecified)
0.246 0.753 0.000
M49.88 Spondylopathy in other diseases classified elsewhere (Sacral and sacrococcygeal region)
0.246 0.753 0.000
M49.87 Spondylopathy in other diseases classified elsewhere (Lumbosacral region)
0.246 0.753 0.000
M49.86 Spondylopathy in other diseases classified elsewhere (Lumbar region)
0.246 0.753 0.000
M49.85 Spondylopathy in other diseases classified elsewhere (Thoracolumbar region)
0.246 0.753 0.000
M49.84 Spondylopathy in other diseases classified elsewhere (Thoracic region)
0.246 0.753 0.000
M49.83 Spondylopathy in other diseases classified elsewhere (Cervicothoracic region)
0.246 0.753 0.000
M49.82 Spondylopathy in other diseases classified elsewhere (Cervical region)
0.246 0.753 0.000
M49.81 Spondylopathy in other diseases classified elsewhere (Occipito-atlanto-axial region)
0.246 0.753 0.000
M49.80 Spondylopathy in other diseases classified elsewhere (Multiple sites in spine)
0.246 0.753 0.000
E23.6 Other disorders of pituitary gland
0.000 0.756 0.243
E67.8 Other specified hyperalimentation
0.000 0.757 0.243
E67.3 Hypervitaminosis D
0.000 0.757 0.243
E67.2 Megavitamin-B6 syndrome
0.000 0.757 0.243
E67.1 Hypercarotenaemia
0.000 0.757 0.243
E67.0 Hypervitaminosis A
0.000 0.757 0.243
M47.0 Anterior spinal and vertebral artery compression syndromes
0.234 0.766 0.000
E28.9 Ovarian dysfunction, unspecified
0.001 0.768 0.232
E28.8 Other ovarian dysfunction
0.001 0.768 0.232
E28.1 Androgen excess
0.001 0.768 0.232

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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