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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs4959235
log Bayes Factor = <0.0001
Chromosome 6   position 3,359,337  (GRCh37) Explore rs4959235 on Ensembl!
Variant rs4959235 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
N21.0 Calculus in bladder
0.000 0.995 0.005
M89.97 Disorder of bone, unspecified (Ankle and foot)
0.000 0.995 0.005
D86.9 Sarcoidosis, unspecified
0.004 0.996 0.000
D86 Sarcoidosis
0.004 0.996 0.000
D86.0 Sarcoidosis of lung
0.004 0.996 0.000
D86.1 Sarcoidosis of lymph nodes
0.004 0.996 0.000
D86.8 Sarcoidosis of other and combined sites
0.004 0.996 0.000
T39.1 4-Aminophenol derivatives
0.000 0.996 0.004
M65.96 Synovitis and tenosynovitis, unspecified (Lower leg)
0.004 0.996 0.000
D86.3 Sarcoidosis of skin
0.003 0.997 0.000
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes
0.003 0.997 0.000
Z50.9 Care involving use of rehabilitation procedure, unspecified
0.000 0.997 0.003
S82.10 Fracture of upper end of tibia (closed)
0.000 0.997 0.003
M89.9 Disorder of bone, unspecified
0.000 0.997 0.003
W25.9 Unspecified place
0.000 0.997 0.003
S42.40 Fracture of lower end of humerus (closed)
0.003 0.997 0.000
M89.91 Disorder of bone, unspecified (Shoulder region)
0.000 0.998 0.002
M65.9 Synovitis and tenosynovitis, unspecified
0.002 0.998 0.000
K14.0 Glossitis
0.002 0.998 0.000
M89.96 Disorder of bone, unspecified (Lower leg)
0.000 0.998 0.002
M89.90 Disorder of bone, unspecified (Multiple sites)
0.000 0.998 0.002
M89.92 Disorder of bone, unspecified (Upper arm)
0.000 0.998 0.002
M89.99 Disorder of bone, unspecified (Site unspecified)
0.000 0.998 0.002
Z86.3 Personal history of endocrine, nutritional and metabolic diseases
0.000 0.998 0.002
N21 Calculus of lower urinary tract
0.000 0.998 0.002
M65.92 Synovitis and tenosynovitis, unspecified (Upper arm)
0.002 0.998 0.000
M89.94 Disorder of bone, unspecified (Hand)
0.000 0.998 0.002
M89.93 Disorder of bone, unspecified (Forearm)
0.000 0.998 0.002
M89.98 Disorder of bone, unspecified (Other)
0.000 0.998 0.002
M89.95 Disorder of bone, unspecified (Pelvic region and thigh)
0.000 0.998 0.002
M65.90 Synovitis and tenosynovitis, unspecified (Multiple sites)
0.002 0.998 0.000
S27.00 Traumatic pneumothorax (without open wound into thoracic cavity)
0.002 0.998 0.000
Z50.0 Cardiac rehabilitation
0.002 0.998 0.000
G50.0 Trigeminal neuralgia
0.002 0.998 0.000
M65.99 Synovitis and tenosynovitis, unspecified (Site unspecified)
0.002 0.998 0.000
E14.9 Without complications
0.000 0.998 0.002
M65.93 Synovitis and tenosynovitis, unspecified (Forearm)
0.002 0.998 0.000
N21.8 Other lower urinary tract calculus
0.000 0.998 0.002
M65.98 Synovitis and tenosynovitis, unspecified (Other)
0.002 0.998 0.000
M65.94 Synovitis and tenosynovitis, unspecified (Hand)
0.002 0.998 0.000
M65.91 Synovitis and tenosynovitis, unspecified (Shoulder region)
0.002 0.998 0.000
K51.9 Ulcerative colitis, unspecified
0.000 0.998 0.002
M65.95 Synovitis and tenosynovitis, unspecified (Pelvic region and thigh)
0.002 0.998 0.000
S82.60 Fracture of lateral malleolus (closed)
0.002 0.998 0.000
N21.9 Calculus of lower urinary tract, unspecified
0.000 0.998 0.002
R60.0 Localised oedema
0.002 0.998 0.000
Z39.0 Care and examination immediately after delivery
0.000 0.998 0.002
H91.9 Hearing loss, unspecified
0.002 0.998 0.000
E23.0 Hypopituitarism
0.000 0.998 0.002
K51.8 Other ulcerative colitis
0.000 0.998 0.002
O32.2 Maternal care for transverse and oblique lie
0.000 0.998 0.002
B97.8 Other viral agents as the cause of diseases classified to other chapters
0.002 0.998 0.000
D22.5 Melanocytic naevi of trunk
0.002 0.998 0.000
S82.1 Fracture of upper end of tibia
0.000 0.998 0.002
N21.1 Calculus in urethra
0.000 0.998 0.001
H80.9 Otosclerosis, unspecified
0.002 0.998 0.000
O32.1 Maternal care for breech presentation
0.000 0.998 0.002
D37.7 Other digestive organs
0.002 0.998 0.000
O32.9 Maternal care for malpresentation of foetus, unspecified
0.000 0.998 0.002
H02.8 Other specified disorders of eyelid
0.002 0.998 0.000
J92.9 Pleural plaque without asbestos
0.000 0.998 0.002
R09.1 Pleurisy
0.000 0.998 0.002
E24 Cushing's syndrome
0.000 0.998 0.002
D80-D89 Certain disorders involving the immune mechanism
0.002 0.998 0.000
E24.9 Cushing's syndrome, unspecified
0.000 0.998 0.001
E24.8 Other Cushing's syndrome
0.000 0.998 0.001
D48.1 Connective and other soft tissue
0.001 0.998 0.000
S42.4 Fracture of lower end of humerus
0.001 0.998 0.000
M65.97 Synovitis and tenosynovitis, unspecified (Ankle and foot)
0.001 0.998 0.000
D37.9 Digestive organ, unspecified
0.001 0.998 0.000
E24.0 Pituitary-dependent Cushing's disease
0.000 0.998 0.001
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.002 0.998 0.000
M23.30 Other meniscus derangements (Multiple sites)
0.001 0.998 0.000
M40.24 Other and unspecified kyphosis (Thoracic region)
0.000 0.998 0.001
E24.2 Drug-induced Cushing's syndrome
0.000 0.998 0.001
K51 Ulcerative colitis
0.000 0.998 0.001
D22.7 Melanocytic naevi of lower limb, including hip
0.001 0.999 0.000
D48.5 Skin
0.001 0.999 0.000
I49.9 Cardiac arrhythmia, unspecified
0.001 0.999 0.000
K51.3 Ulcerative (chronic) rectosigmoiditis
0.000 0.999 0.001
W25 Contact with sharp glass
0.000 0.999 0.001
N80.0 Endometriosis of uterus
0.000 0.999 0.001
D24 Benign neoplasm of breast
0.001 0.999 0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs
0.001 0.999 0.000
S42.41 Fracture of lower end of humerus (open)
0.001 0.999 0.000
S82.11 Fracture of upper end of tibia (open)
0.000 0.999 0.001
D37.6 Liver, gallbladder and bile ducts
0.001 0.999 0.000
J94.8 Other specified pleural conditions
0.000 0.999 0.001
L50.9 Urticaria, unspecified
0.000 0.999 0.001
L89.9 Decubitus ulcer and pressure area, unspecified
0.000 0.999 0.001
D83 Common variable immunodeficiency
0.001 0.999 0.000
E23 Hypofunction and other disorders of pituitary gland
0.000 0.999 0.001
D22.4 Melanocytic naevi of scalp and neck
0.001 0.999 0.000
D37.1 Stomach
0.001 0.999 0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.999 0.001
E22.1 Hyperprolactinaemia
0.000 0.999 0.001
Q51.3 Bicornate uterus
0.000 0.999 0.001
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.999 0.001
E24.3 Ectopic ACTH syndrome
0.000 0.999 0.001
E24.1 Nelson's syndrome
0.000 0.999 0.001
E27.8 Other specified disorders of adrenal gland
0.000 0.999 0.001
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.001 0.999 0.000
D81 Combined immunodeficiencies
0.001 0.999 0.000
M89.86 Other specified disorders of bone (Lower leg)
0.000 0.999 0.001
D37.3 Appendix
0.001 0.999 0.000
D41.0 Kidney
0.001 0.999 0.000
K51.4 Pseudopolyposis of colon
0.000 0.999 0.001
T40.4 Other synthetic narcotics
0.000 0.999 0.001
D84 Other immunodeficiencies
0.001 0.999 0.000
D37.2 Small intestine
0.001 0.999 0.000
D41.2 Ureter
0.001 0.999 0.000
D48.2 Peripheral nerves and autonomic nervous system
0.001 0.999 0.000
K51.1 Ulcerative (chronic) ileocolitis
0.000 0.999 0.001
L50.0 Allergic urticaria
0.000 0.999 0.001
S27.0 Traumatic pneumothorax
0.001 0.999 0.000
D82 Immunodeficiency associated with other major defects
0.001 0.999 0.000
E22 Hyperfunction of pituitary gland
0.000 0.999 0.001
O32 Maternal care for known or suspected malpresentation of foetus
0.000 0.999 0.001
D41.1 Renal pelvis
0.001 0.999 0.000
E29.1 Testicular hypofunction
0.000 0.999 0.001
I22.9 Subsequent myocardial infarction of unspecified site
0.001 0.999 0.000
Z08.0 Follow-up examination after surgery for malignant neoplasm
0.000 0.999 0.001
M89 Other disorders of bone
0.000 0.999 0.001
D48.9 Neoplasms of uncertain or unknown behaviour, unspecified
0.001 0.999 0.000
D48.4 Peritoneum
0.001 0.999 0.000
J39.2 Other diseases of pharynx
0.000 0.999 0.001
W25.8 Other specified place
0.000 0.999 0.001
D80 Immunodeficiency with predominantly antibody defects
0.001 0.999 0.000
M40.29 Other and unspecified kyphosis (Site unspecified)
0.000 0.999 0.001
D37.4 Colon
0.001 0.999 0.000
D46.2 Refractory anaemia with excess of blasts
0.001 0.999 0.000
D83.9 Common variable immunodeficiency, unspecified
0.001 0.999 0.000
E23.6 Other disorders of pituitary gland
0.000 0.999 0.001
K51.2 Ulcerative (chronic) proctitis
0.000 0.999 0.001
T88.7 Unspecified adverse effect of drug or medicament
0.000 0.999 0.001
W25.6 Industrial and construction area
0.000 0.999 0.001
W25.5 Trade and service area
0.000 0.999 0.001
W25.1 Residential institution
0.000 0.999 0.001
W25.0 Home
0.000 0.999 0.001
W25.7 Farm
0.000 0.999 0.001
W25.4 Street and highway
0.000 0.999 0.001
W25.3 Sports and athletics area
0.000 0.999 0.001
D46 Myelodysplastic syndromes
0.001 0.999 0.000
R15 Faecal incontinence
0.000 0.999 0.001
D37-D48 Neoplasms of uncertain or unknown behaviour
0.001 0.999 0.000
D41.9 Urinary organ, unspecified
0.001 0.999 0.000
D41.7 Other urinary organs
0.001 0.999 0.000
D41.3 Urethra
0.001 0.999 0.000
D46.7 Other myelodysplastic syndromes
0.001 0.999 0.000
D48.3 Retroperitoneum
0.001 0.999 0.000
J06.9 Acute upper respiratory infection, unspecified
0.000 0.999 0.001
W25.2 School, other institution and public administrative area
0.000 0.999 0.001
E29 Testicular dysfunction
0.000 0.999 0.001
S27.01 Traumatic pneumothorax (with open wound into thoracic cavity)
0.001 0.999 0.000
D41.4 Bladder
0.001 0.999 0.000
D80.2 Selective deficiency of immunoglobulin A [IgA]
0.001 0.999 0.000
D83.8 Other common variable immunodeficiencies
0.001 0.999 0.000
D83.2 Common variable immunodeficiency with autoantibodies to B- or T-cells
0.001 0.999 0.000
D83.1 Common variable immunodeficiency with predominant immunoregulatory T-cell disorders
0.001 0.999 0.000
D83.0 Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function
0.001 0.999 0.000
E23.7 Disorder of pituitary gland, unspecified
0.000 0.999 0.001
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.999 0.001
E23.1 Drug-induced hypopituitarism
0.000 0.999 0.001
J38.1 Polyp of vocal cord and larynx
0.001 0.999 0.000
S61.8 Open wound of other parts of wrist and hand
0.000 0.999 0.001
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.001 0.999 0.000
H80 Otosclerosis
0.001 0.999 0.000
B97.7 Papillomavirus as the cause of diseases classified to other chapters
0.001 0.999 0.000
D43.2 Brain, unspecified
0.001 0.999 0.000
D81.9 Combined immunodeficiency, unspecified
0.001 0.999 0.000
D81.8 Other combined immunodeficiencies
0.001 0.999 0.000
D81.7 Major histocompatibility complex class II deficiency
0.001 0.999 0.000
D81.6 Major histocompatibility complex class I deficiency
0.001 0.999 0.000
D81.5 Purine nucleoside phosphorylase [PNP] deficiency
0.001 0.999 0.000
D81.4 Nezelof's syndrome
0.001 0.999 0.000
D81.3 Adenosine deaminase [ADA] deficiency
0.001 0.999 0.000
D81.2 Severe combined immunodeficiency [SCID] with low or normal B-cell numbers
0.001 0.999 0.000
D81.1 Severe combined immunodeficiency [SCID] with low T- and B-cell numbers
0.001 0.999 0.000
D81.0 Severe combined immunodeficiency [SCID] with reticular dysgenesis
0.001 0.999 0.000
D84.8 Other specified immunodeficiencies
0.001 0.999 0.000
D84.1 Defects in the complement system
0.001 0.999 0.000
L50.1 Idiopathic urticaria
0.000 0.999 0.001
D89 Other disorders involving the immune mechanism, not elsewhere classified
0.001 0.999 0.000
E27 Other disorders of adrenal gland
0.000 0.999 0.001
L50 Urticaria
0.000 0.999 0.001
M65 Synovitis and tenosynovitis
0.001 0.999 0.000
E20-E35 Disorders of other endocrine glands
0.000 0.999 0.001
M40.26 Other and unspecified kyphosis (Lumbar region)
0.000 0.999 0.001
D82.1 Di George's syndrome
0.001 0.999 0.000
D84.0 Lymphocyte function antigen-1 [LFA-1] defect
0.001 0.999 0.000
E22.8 Other hyperfunction of pituitary gland
0.000 0.999 0.001
M40.2 Other and unspecified kyphosis
0.000 0.999 0.001
M89.8 Other specified disorders of bone
0.000 0.999 0.001
O32.8 Maternal care for other malpresentation of foetus
0.000 0.999 0.001
M40.22 Other and unspecified kyphosis (Cervical region)
0.000 0.999 0.001
D22.2 Melanocytic naevi of ear and external auricular canal
0.001 0.999 0.000
D37.0 Lip, oral cavity and pharynx
0.001 0.999 0.000
D80.9 Immunodeficiency with predominantly antibody defects, unspecified
0.001 0.999 0.000
D82.9 Immunodeficiency associated with major defect, unspecified
0.001 0.999 0.000
D82.8 Immunodeficiency associated with other specified major defects
0.001 0.999 0.000
D82.4 Hyperimmunoglobulin E [IgE] syndrome
0.001 0.999 0.000
D82.2 Immunodeficiency with short-limbed stature
0.001 0.999 0.000
D82.0 Wiskott-Aldrich syndrome
0.001 0.999 0.000
E27.9 Disorder of adrenal gland, unspecified
0.000 0.999 0.001
M65.3 Trigger finger
0.001 0.999 0.000
M89.6 Osteopathy after poliomyelitis
0.000 0.999 0.001
M89.2 Other disorders of bone development and growth
0.000 0.999 0.001
M89.1 Epiphyseal arrest
0.000 0.999 0.001
D42 Neoplasm of uncertain or unknown behaviour of meninges
0.001 0.999 0.000
D45 Polycythaemia vera
0.001 0.999 0.000
D44.4 Craniopharyngeal duct
0.001 0.999 0.000
D46.1 Refractory anaemia with sideroblasts
0.001 0.999 0.000
D47.1 Chronic myeloproliferative disease
0.001 0.999 0.000
D80.7 Transient hypogammaglobulinaemia of infancy
0.001 0.999 0.000
D80.5 Immunodeficiency with increased immunoglobulin M [IgM]
0.001 0.999 0.000
D80.4 Selective deficiency of immunoglobulin M [IgM]
0.001 0.999 0.000
D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses
0.001 0.999 0.000
D80.0 Hereditary hypogammaglobulinaemia
0.001 0.999 0.000
I07.1 Tricuspid insufficiency
0.001 0.999 0.000
I49.3 Ventricular premature depolarisation
0.001 0.999 0.000
L50.8 Other urticaria
0.000 0.999 0.001
M89.5 Osteolysis
0.000 0.999 0.001
O32.0 Maternal care for unstable lie
0.000 0.999 0.001
R39.8 Other and unspecified symptoms and signs involving the urinary system
0.001 0.999 0.000
E31 Polyglandular dysfunction
0.000 0.999 0.001
H91 Other hearing loss
0.001 0.999 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.000 0.999 0.001
M65.34 Trigger finger-Hand
0.001 0.999 0.000
W25.09 Contact with sharp glass; Home; During unspecified activity
0.000 0.999 0.001
W25.03 Contact with sharp glass; Home; While engaged in other types of work
0.000 0.999 0.001
W25.18 Contact with sharp glass; Residential institution;While engaged in other specified activities
0.000 0.999 0.001
W25.52 Contact with sharp glass; Trade and service area;While working for income
0.000 0.999 0.001
W25.62 Contact with sharp glass; Industrial and construction area ;While working for income
0.000 0.999 0.001
D46.6 Myelodysplastic syndrome with isolated del(5q) chromosomal abnormality
0.001 0.999 0.000
D46.5 Refractory anaemia with multi-lineage dysplasia
0.001 0.999 0.000
D46.3 Refractory anaemia with excess of blasts with transformation
0.001 0.999 0.000
D47.4 Osteomyelofibrosis
0.001 0.999 0.000
D80.8 Other immunodeficiencies with predominantly antibody defects
0.001 0.999 0.000
D80.6 Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinaemia
0.001 0.999 0.000
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.999 0.001
E29.8 Other testicular dysfunction
0.000 0.999 0.001
E29.0 Testicular hyperfunction
0.000 0.999 0.001
E31.0 Autoimmune polyglandular failure
0.000 0.999 0.001
H91.8 Other specified hearing loss
0.001 0.999 0.000
M65.0 Abscess of tendon sheath
0.001 0.999 0.000
M89.4 Other hypertrophic osteo-arthropathy
0.000 0.999 0.001
R87.6 Abnormal cytological findings
0.001 0.999 0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands
0.001 0.999 0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.001 0.999 0.000
M89.85 Other specified disorders of bone (Pelvic region and thigh)
0.000 0.999 0.001
D42.9 Meninges, unspecified
0.001 0.999 0.000
D43.9 Central nervous system, unspecified
0.001 0.999 0.000
D43.7 Other parts of central nervous system
0.001 0.999 0.000
D43.3 Cranial nerves
0.001 0.999 0.000
D43.1 Brain, infratentorial
0.001 0.999 0.000
D43.0 Brain, supratentorial
0.001 0.999 0.000
D46.0 Refractory anaemia without sideroblasts, so stated
0.001 0.999 0.000
D84.9 Immunodeficiency, unspecified
0.001 0.999 0.000
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified
0.001 0.999 0.000
D89.0 Polyclonal hypergammaglobulinaemia
0.001 0.999 0.000
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.999 0.001
E29.9 Testicular dysfunction, unspecified
0.000 0.999 0.001
H80.2 Cochlear otosclerosis
0.001 0.999 0.000
H80.1 Otosclerosis involving oval window, obliterative
0.001 0.999 0.000
H80.0 Otosclerosis involving oval window, nonobliterative
0.001 0.999 0.000
H91.0 Ototoxic hearing loss
0.001 0.999 0.000
M65.2 Calcific tendinitis
0.001 0.999 0.000
O32.6 Maternal care for compound presentation
0.000 0.999 0.001
T42.0 Hydantoin derivatives
0.000 0.999 0.001
M40.28 Other and unspecified kyphosis (Sacral and sacrococcygeal region)
0.000 0.999 0.001
M40.27 Other and unspecified kyphosis (Lumbosacral region)
0.000 0.999 0.001
M40.23 Other and unspecified kyphosis (Cervicothoracic region)
0.000 0.999 0.001
M40.21 Other and unspecified kyphosis (Occipito-atlanto-axial region)
0.000 0.999 0.001
M40.20 Other and unspecified kyphosis (Multiple sites in spine)
0.000 0.999 0.001
M54.39 Sciatica (Site unspecified)
0.001 0.999 0.000
M65.84 Other synovitis and tenosynovitis (Hand)
0.001 0.999 0.000
M89.03 Algoneurodystrophy (Forearm)
0.000 0.999 0.001
M89.82 Other specified disorders of bone (Upper arm)
0.000 0.999 0.001
M89.80 Other specified disorders of bone (Multiple sites)
0.000 0.999 0.001
B97.4 Respiratory synctial virus as the cause of diseases classified to other chapters
0.001 0.999 0.000
D22.1 Melanocytic naevi of eyelid, including canthus
0.001 0.999 0.000
D39.1 Ovary
0.001 0.999 0.000
D44.0 Thyroid gland
0.001 0.999 0.000
D48.7 Other specified sites
0.001 0.999 0.000
D82.3 Immunodeficiency following hereditary defective response to Epstein-Barr virus
0.001 0.999 0.000
D89.3 Immune reconstitution syndrome
0.001 0.999 0.000
E27.5 Adrenomedullary hyperfunction
0.000 0.999 0.001
E27.0 Other adrenocortical overactivity
0.000 0.999 0.001
H80.8 Other otosclerosis
0.001 0.999 0.000
H91.1 Presbycusis
0.001 0.999 0.000
L50.6 Contact urticaria
0.000 0.999 0.001
L50.5 Cholinergic urticaria
0.000 0.999 0.001
L50.4 Vibratory urticaria
0.000 0.999 0.001
L50.2 Urticaria due to cold and heat
0.000 0.999 0.001
M65.8 Other synovitis and tenosynovitis
0.001 0.999 0.000
O32.4 Maternal care for high head at term
0.000 0.999 0.001
S81.0 Open wound of knee
0.000 0.999 0.001
Z74.0 Reduced mobility
0.001 0.999 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.001 0.999 0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs
0.001 0.999 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.999 0.001
E30 Disorders of puberty, not elsewhere classified
0.000 0.999 0.001
E26 Hyperaldosteronism
0.000 0.999 0.001
E25 Adrenogenital disorders
0.000 0.999 0.001
M40.25 Other and unspecified kyphosis (Thoracolumbar region)
0.000 0.999 0.001
M65.04 Abscess of tendon sheath (Hand)
0.001 0.999 0.000
M65.39 Trigger finger-Site unspec
0.001 0.999 0.000
M65.38 Trigger finger-Other
0.001 0.999 0.000
M65.37 Trigger finger-Ankle/foot
0.001 0.999 0.000
M65.36 Trigger finger-Lower leg
0.001 0.999 0.000
M65.35 Trigger finger-Pelvic/thigh
0.001 0.999 0.000
M65.33 Trigger finger-Forearm
0.001 0.999 0.000
M65.32 Trigger finger-Upper arm
0.001 0.999 0.000
M65.31 Trigger finger-Shldr region
0.001 0.999 0.000
M65.30 Trigger finger-Mult sites
0.001 0.999 0.000
M65.81 Other synovitis and tenosynovitis (Shoulder region)
0.001 0.999 0.000
M89.19 Epiphyseal arrest (Site unspecified)
0.000 0.999 0.001
M89.18 Epiphyseal arrest (Other)
0.000 0.999 0.001
M89.17 Epiphyseal arrest (Ankle and foot)
0.000 0.999 0.001
M89.16 Epiphyseal arrest (Lower leg)
0.000 0.999 0.001
M89.15 Epiphyseal arrest (Pelvic region and thigh)
0.000 0.999 0.001
M89.14 Epiphyseal arrest (Hand)
0.000 0.999 0.001
M89.13 Epiphyseal arrest (Forearm)
0.000 0.999 0.001
M89.12 Epiphyseal arrest (Upper arm)
0.000 0.999 0.001
M89.11 Epiphyseal arrest (Shoulder region)
0.000 0.999 0.001
M89.10 Epiphyseal arrest (Multiple sites)
0.000 0.999 0.001
M89.29 Other disorders of bone development and growth (Site unspecified)
0.000 0.999 0.001
M89.28 Other disorders of bone development and growth (Other)
0.000 0.999 0.001
M89.27 Other disorders of bone development and growth (Ankle and foot)
0.000 0.999 0.001
M89.26 Other disorders of bone development and growth (Lower leg)
0.000 0.999 0.001
M89.25 Other disorders of bone development and growth (Pelvic region and thigh)
0.000 0.999 0.001
M89.24 Other disorders of bone development and growth (Hand)
0.000 0.999 0.001
M89.23 Other disorders of bone development and growth (Forearm)
0.000 0.999 0.001
M89.22 Other disorders of bone development and growth (Upper arm)
0.000 0.999 0.001
M89.21 Other disorders of bone development and growth (Shoulder region)
0.000 0.999 0.001
M89.20 Other disorders of bone development and growth (Multiple sites)
0.000 0.999 0.001
M89.69 Osteopathy after poliomyelitis (Site unspecified)
0.000 0.999 0.001
M89.68 Osteopathy after poliomyelitis (Other)
0.000 0.999 0.001
M89.67 Osteopathy after poliomyelitis (Ankle and foot)
0.000 0.999 0.001
M89.66 Osteopathy after poliomyelitis (Lower leg)
0.000 0.999 0.001
M89.65 Osteopathy after poliomyelitis (Pelvic region and thigh)
0.000 0.999 0.001
M89.64 Osteopathy after poliomyelitis (Hand)
0.000 0.999 0.001
M89.63 Osteopathy after poliomyelitis (Forearm)
0.000 0.999 0.001
M89.62 Osteopathy after poliomyelitis (Upper arm)
0.000 0.999 0.001
M89.61 Osteopathy after poliomyelitis (Shoulder region)
0.000 0.999 0.001
M89.60 Osteopathy after poliomyelitis (Multiple sites)
0.000 0.999 0.001
M89.84 Other specified disorders of bone (Hand)
0.000 0.999 0.001
D38.5 Other respiratory organs
0.001 0.999 0.000
D38.2 Pleura
0.001 0.999 0.000
D42.1 Spinal meninges
0.001 0.999 0.000
D42.0 Cerebral meninges
0.001 0.999 0.000
D44.6 Carotid body
0.001 0.999 0.000
D47.7 Other specified neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.001 0.999 0.000
E07.9 Disorder of thyroid, unspecified
0.000 0.999 0.001
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.999 0.001
H40.1 Primary open-angle glaucoma
0.000 0.999 0.001
M89.3 Hypertrophy of bone
0.000 0.999 0.001
M89.0 Algoneurodystrophy
0.000 0.999 0.001
O32.5 Maternal care for multiple gestation with malpresentation of one foetus or more
0.000 0.999 0.001
O32.3 Maternal care for face, brow and chin presentation
0.000 0.999 0.001
S82.6 Fracture of lateral malleolus
0.001 0.999 0.000
S83.5 Sprain and strain involving (anterior)(posterior) cruciate ligament of knee
0.000 0.999 0.001
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified
0.000 0.999 0.001
D22 Melanocytic naevi
0.001 0.999 0.000
M89.00 Algoneurodystrophy (Multiple sites)
0.000 0.999 0.001
M89.59 Osteolysis (Site unspecified)
0.000 0.999 0.001
M89.58 Osteolysis (Other)
0.000 0.999 0.001
M89.57 Osteolysis (Ankle and foot)
0.000 0.999 0.001
M89.56 Osteolysis (Lower leg)
0.000 0.999 0.001
M89.54 Osteolysis (Hand)
0.000 0.999 0.001
M89.53 Osteolysis (Forearm)
0.000 0.999 0.001
M89.52 Osteolysis (Upper arm)
0.000 0.999 0.001
M89.51 Osteolysis (Shoulder region)
0.000 0.999 0.001
M89.50 Osteolysis (Multiple sites)
0.000 0.999 0.001
M89.89 Other specified disorders of bone (Site unspecified)
0.000 0.999 0.001
M89.83 Other specified disorders of bone (Forearm)
0.000 0.999 0.001
M89.81 Other specified disorders of bone (Shoulder region)
0.000 0.999 0.001
A04.7 Enterocolitis due to Clostridium difficile
0.001 0.999 0.000
D38.0 Larynx
0.001 0.999 0.000
D43.4 Spinal cord
0.001 0.999 0.000
D89.1 Cryoglobulinaemia
0.001 0.999 0.000
E22.0 Acromegaly and pituitary gigantism
0.000 0.999 0.001
E27.2 Addisonian crisis
0.000 0.999 0.001
E31.9 Polyglandular dysfunction, unspecified
0.000 0.999 0.001
E31.8 Other polyglandular dysfunction
0.000 0.999 0.001
E31.1 Polyglandular hyperfunction
0.000 0.999 0.001
L50.3 Dermatographic urticaria
0.000 0.999 0.001
M65.1 Other infective (teno)synovitis
0.001 0.999 0.000
T39.4 Antirheumatics, not elsewhere classified
0.000 0.999 0.001
T39.2 Pyrazolone derivatives
0.000 0.999 0.001
T42.4 Benzodiazepines
0.000 0.999 0.001
E20 Hypoparathyroidism
0.000 0.999 0.001
M65.09 Abscess of tendon sheath (Site unspecified)
0.001 0.999 0.000
M65.08 Abscess of tendon sheath (Other)
0.001 0.999 0.000
M65.07 Abscess of tendon sheath (Ankle and foot)
0.001 0.999 0.000
M65.06 Abscess of tendon sheath (Lower leg)
0.001 0.999 0.000
M65.05 Abscess of tendon sheath (Pelvic region and thigh)
0.001 0.999 0.000
M65.03 Abscess of tendon sheath (Forearm)
0.001 0.999 0.000
M65.02 Abscess of tendon sheath (Upper arm)
0.001 0.999 0.000
M65.01 Abscess of tendon sheath (Shoulder region)
0.001 0.999 0.000
M65.00 Abscess of tendon sheath (Multiple sites)
0.001 0.999 0.000
M65.87 Other synovitis and tenosynovitis (Ankle and foot)
0.001 0.999 0.000
M89.49 Other hypertrophic osteoarthropathy (Site unspecified)
0.000 0.999 0.001
M89.48 Other hypertrophic osteoarthropathy (Other)
0.000 0.999 0.001
M89.47 Other hypertrophic osteoarthropathy (Ankle and foot)
0.000 0.999 0.001
M89.46 Other hypertrophic osteoarthropathy (Lower leg)
0.000 0.999 0.001
M89.45 Other hypertrophic osteoarthropathy (Pelvic region and thigh)
0.000 0.999 0.001
M89.44 Other hypertrophic osteoarthropathy (Hand)
0.000 0.999 0.001
M89.43 Other hypertrophic osteoarthropathy (Forearm)
0.000 0.999 0.001
M89.42 Other hypertrophic osteoarthropathy (Upper arm)
0.000 0.999 0.001
M89.41 Other hypertrophic osteoarthropathy (Shoulder region)
0.000 0.999 0.001
M89.55 Osteolysis (Pelvic region and thigh)
0.000 0.999 0.001
M89.88 Other specified disorders of bone (Other)
0.000 0.999 0.001
D38.6 Respiratory organ, unspecified
0.001 0.999 0.000
D38.4 Thymus
0.001 0.999 0.000
D38.3 Mediastinum
0.001 0.999 0.000
D44.9 Endocrine gland, unspecified
0.001 0.999 0.000
D44.7 Aortic body and other paraganglia
0.001 0.999 0.000
D44.5 Pineal gland
0.001 0.999 0.000
D44.2 Parathyroid gland
0.001 0.999 0.000
D46.9 Myelodysplastic syndrome, unspecified
0.001 0.999 0.000
D46.4 Refractory anaemia, unspecified
0.001 0.999 0.000
D48.0 Bone and articular cartilage
0.001 0.999 0.001
E87.0 Hyperosmolality and hypernatraemia
0.001 0.999 0.000
H81.9 Disorder of vestibular function, unspecified
0.001 0.999 0.000
H91.3 Deaf mutism, not elsewhere classified
0.001 0.999 0.000
K51.0 Ulcerative (chronic) enterocolitis
0.000 0.999 0.001
T93.8 Sequelae of other specified injuries of lower limb
0.000 0.999 0.001
B97 Viral agents as the cause of diseases classified to other chapters
0.001 0.999 0.000
E34 Other endocrine disorders
0.000 0.999 0.001
E32 Diseases of thymus
0.000 0.999 0.001
M65.29 Calcific tendinitis (Site unspecified)
0.001 0.999 0.000
M65.28 Calcific tendinitis (Other)
0.001 0.999 0.000
M65.27 Calcific tendinitis (Ankle and foot)
0.001 0.999 0.000
M65.26 Calcific tendinitis (Lower leg)
0.001 0.999 0.000
M65.25 Calcific tendinitis (Pelvic region and thigh)
0.001 0.999 0.000
M65.24 Calcific tendinitis (Hand)
0.001 0.999 0.000
M65.23 Calcific tendinitis (Forearm)
0.001 0.999 0.000
M65.22 Calcific tendinitis (Upper arm)
0.001 0.999 0.000
M65.21 Calcific tendinitis (Shoulder region)
0.001 0.999 0.000
M65.20 Calcific tendinitis (Multiple sites)
0.001 0.999 0.000
M65.89 Other synovitis and tenosynovitis (Site unspecified)
0.001 0.999 0.000
M65.88 Other synovitis and tenosynovitis (Other)
0.001 0.999 0.000
M65.85 Other synovitis and tenosynovitis (Pelvic region and thigh)
0.001 0.999 0.000
M65.82 Other synovitis and tenosynovitis (Upper arm)
0.001 0.999 0.000
M65.80 Other synovitis and tenosynovitis (Multiple sites)
0.001 0.999 0.000
S82.61 Fracture of lateral malleolus (open)
0.001 0.999 0.000
D39.9 Female genital organ, unspecified
0.001 0.999 0.000
D39.2 Placenta
0.001 0.999 0.000
D47.5 Chronic eosinophilic leukaemia [hypereosinophilic syndrome]
0.001 0.999 0.000
D48.6 Breast
0.001 0.999 0.000
D89.9 Disorder involving the immune mechanism, unspecified
0.001 0.999 0.000
E25.9 Adrenogenital disorder, unspecified
0.000 0.999 0.001
E25.8 Other adrenogenital disorders
0.000 0.999 0.001
E26.9 Hyperaldosteronism, unspecified
0.000 0.999 0.001
E26.8 Other hyperaldosteronism
0.000 0.999 0.001
E26.1 Secondary hyperaldosteronism
0.000 0.999 0.001
E26.0 Primary hyperaldosteronism
0.000 0.999 0.001
E30.9 Disorder of puberty, unspecified
0.000 0.999 0.001
E30.8 Other disorders of puberty
0.000 0.999 0.001
E30.1 Precocious puberty
0.000 0.999 0.001
E30.0 Delayed puberty
0.000 0.999 0.001
E34.9 Endocrine disorder, unspecified
0.000 0.999 0.001
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.999 0.001
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.999 0.001
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.999 0.001
H91.2 Sudden idiopathic hearing loss
0.001 0.999 0.000
O43.1 Malformation of placenta
0.000 0.999 0.001
M89.08 Algoneurodystrophy (Other)
0.000 0.999 0.001
M89.05 Algoneurodystrophy (Pelvic region and thigh)
0.000 0.999 0.001
M89.02 Algoneurodystrophy (Upper arm)
0.000 0.999 0.001
M89.39 Hypertrophy of bone (Site unspecified)
0.000 0.999 0.001
M89.38 Hypertrophy of bone (Other)
0.000 0.999 0.001
M89.36 Hypertrophy of bone (Lower leg)
0.000 0.999 0.001
M89.35 Hypertrophy of bone (Pelvic region and thigh)
0.000 0.999 0.001
M89.34 Hypertrophy of bone (Hand)
0.000 0.999 0.001
M89.33 Hypertrophy of bone (Forearm)
0.000 0.999 0.001
M89.32 Hypertrophy of bone (Upper arm)
0.000 0.999 0.001
M89.31 Hypertrophy of bone (Shoulder region)
0.000 0.999 0.001
M89.30 Hypertrophy of bone (Multiple sites)
0.000 0.999 0.001
M89.40 Other hypertrophic osteoarthropathy (Multiple sites)
0.000 0.999 0.001
D89.2 Hypergammaglobulinaemia, unspecified
0.001 0.999 0.000
E21.0 Primary hyperparathyroidism
0.000 0.999 0.001
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.999 0.001
E34.3 Short stature, not elsewhere classified
0.000 0.999 0.001
K51.5 Mucosal proctocolitis
0.000 0.999 0.001
O80.9 Single spontaneous delivery, unspecified
0.000 0.999 0.001
M65.19 Other infective (teno)synovitis (Site unspecified)
0.001 0.999 0.000
M65.18 Other infective (teno)synovitis (Other)
0.001 0.999 0.000
M65.17 Other infective (teno)synovitis (Ankle and foot)
0.001 0.999 0.000
M65.16 Other infective (teno)synovitis (Lower leg)
0.001 0.999 0.000
M65.15 Other infective (teno)synovitis (Pelvic region and thigh)
0.001 0.999 0.000
M65.13 Other infective (teno)synovitis (Forearm)
0.001 0.999 0.000
M65.12 Other infective (teno)synovitis (Upper arm)
0.001 0.999 0.000
M65.11 Other infective (teno)synovitis (Shoulder region)
0.001 0.999 0.000
M65.10 Other infective (teno)synovitis (Multiple sites)
0.001 0.999 0.000
M79.79 Fibromyalgia (Site unspecified)
0.001 0.999 0.000
M89.04 Algoneurodystrophy (Hand)
0.000 0.999 0.001
M89.01 Algoneurodystrophy (Shoulder region)
0.000 0.999 0.001
S32.50 Fracture of pubis (closed)
0.001 0.999 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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