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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs4959799
log Bayes Factor = <0.0001
Chromosome 6   position 3,295,028  (GRCh37) Explore rs4959799 on Ensembl!
Variant rs4959799 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
M54 Dorsalgia
0.058 0.942 0.000
M54.4 Lumbago with sciatica
0.057 0.943 0.000
M54.2 Cervicalgia
0.055 0.945 0.000
M54.46 Lumbago with sciatica (Lumbar region)
0.054 0.946 0.000
M54.1 Radiculopathy
0.053 0.947 0.000
M54.29 Cervicalgia-Site unspe
0.051 0.949 0.000
M54.12 Radiculopathy (Cervical region)
0.051 0.949 0.000
M54.49 Lumbago with sciatica (Site unspecified)
0.049 0.951 0.000
M54.47 Lumbago with sciatica (Lumbosacral region)
0.049 0.951 0.000
M50-M54 Other dorsopathies
0.049 0.951 0.000
M54.22 Cervicalgia (Cervical region)
0.047 0.953 0.000
M54.19 Radiculopathy (Site unspecified)
0.046 0.954 0.000
M50 Cervical disk disorders
0.045 0.955 0.000
M51 Other intervertebral disk disorders
0.043 0.957 0.000
M54.8 Other dorsalgia
0.041 0.958 0.000
M54.0 Panniculitis affecting regions of neck and back
0.041 0.958 0.000
M54.48 Lumbago with sciatica (Sacral and sacrococcygeal region)
0.041 0.959 0.000
M54.45 Lumbago with sciatica (Thoracolumbar region)
0.041 0.959 0.000
M54.44 Lumbago with sciatica-Thoracic
0.041 0.959 0.000
M54.43 Lumbago with sciatica-Cervicothoracic
0.041 0.959 0.000
M54.42 Lumbago with sciatica-Cervical
0.041 0.959 0.000
M54.41 Lumbago with sciatica-Occipit-atl-axl
0.041 0.959 0.000
M54.40 Lumbago with sciatica (Multiple sites in spine)
0.041 0.959 0.000
M54.3 Sciatica
0.041 0.959 0.000
M50.3 Other cervical disk degeneration
0.041 0.959 0.000
M54.28 Cervicalgia-Sacral/sacrococ
0.040 0.960 0.000
M54.27 Cervicalgia-Lumbosacral
0.040 0.960 0.000
M54.26 Cervicalgia-Lumbar
0.040 0.960 0.000
M54.25 Cervicalgia-Thoracolumbar
0.040 0.960 0.000
M54.24 Cervicalgia-Thoracic
0.040 0.960 0.000
M54.23 Cervicalgia (Cervicothoracic region)
0.040 0.960 0.000
M54.21 Cervicalgia (Occipito-atlanto-axial region)
0.040 0.960 0.000
M54.20 Cervicalgia-Mult site
0.040 0.960 0.000
M54.9 Dorsalgia, unspecified
0.039 0.961 0.000
M54.15 Radiculopathy (Thoracolumbar region)
0.038 0.962 0.000
M54.14 Radiculopathy (Thoracic region)
0.038 0.962 0.000
M54.13 Radiculopathy (Cervicothoracic region)
0.038 0.962 0.000
M54.11 Radiculopathy (Occipito-atlanto-axial region)
0.038 0.962 0.000
M54.10 Radiculopathy (Multiple sites in spine)
0.038 0.962 0.000
M54.6 Pain in thoracic spine
0.038 0.962 0.000
M54.18 Radiculopathy (Sacral and sacrococcygeal region)
0.038 0.962 0.000
M50.2 Other cervical disk displacement
0.038 0.962 0.000
M51.2 Other specified intervertebral disk displacement
0.037 0.963 0.000
M50.9 Cervical disk disorder, unspecified
0.037 0.963 0.000
M51.0 Lumbar and other intervertebral disk disorders with myelopathy
0.035 0.965 0.000
M54.37 Sciatica (Lumbosacral region)
0.034 0.966 0.000
M54.96 Dorsalgia, unspecified (Lumbar region)
0.034 0.966 0.000
M54.16 Radiculopathy (Lumbar region)
0.033 0.967 0.000
M50.8 Other cervical disk disorders
0.032 0.967 0.000
M53 Other dorsopathies, not elsewhere classified
0.032 0.967 0.000
M54.5 Low back pain
0.032 0.968 0.000
M51.9 Intervertebral disk disorder, unspecified
0.032 0.968 0.000
M51.3 Other specified intervertebral disk degeneration
0.031 0.969 0.000
M51.1 Lumbar and other intervertebral disk disorders with radiculopathy
0.031 0.969 0.000
M51.4 Schmorl's nodes
0.031 0.969 0.000
M54.09 Panniculitis affecting regions of neck and back (Site unspecified)
0.030 0.970 0.000
M54.08 Panniculitis affecting regions of neck and back (Sacral and sacrococcygeal region)
0.030 0.970 0.000
M54.07 Panniculitis affecting regions of neck and back (Lumbosacral region)
0.030 0.970 0.000
M54.06 Panniculitis affecting regions of neck and back (Lumbar region)
0.030 0.970 0.000
M54.05 Panniculitis affecting regions of neck and back (Thoracolumbar region)
0.030 0.970 0.000
M54.04 Panniculitis affecting regions of neck and back (Thoracic region)
0.030 0.970 0.000
M54.03 Panniculitis affecting regions of neck and back (Cervicothoracic region)
0.030 0.970 0.000
M54.02 Panniculitis affecting regions of neck and back (Cervical region)
0.030 0.970 0.000
M54.01 Panniculitis affecting regions of neck and back (Occipito-atlanto-axial region)
0.030 0.970 0.000
M54.00 Panniculitis affecting regions of neck and back (Multiple sites in spine)
0.030 0.970 0.000
M54.89 Other dorsalgia (Site unspecified)
0.030 0.970 0.000
M54.88 Other dorsalgia (Sacral and sacrococcygeal region)
0.030 0.970 0.000
M54.87 Other dorsalgia (Lumbosacral region)
0.030 0.970 0.000
M54.86 Other dorsalgia (Lumbar region)
0.030 0.970 0.000
M54.85 Other dorsalgia (Thoracolumbar region)
0.030 0.970 0.000
M54.84 Other dorsalgia (Thoracic region)
0.030 0.970 0.000
M54.83 Other dorsalgia (Cervicothoracic region)
0.030 0.970 0.000
M54.82 Other dorsalgia (Cervical region)
0.030 0.970 0.000
M54.81 Other dorsalgia (Occipito-atlanto-axial region)
0.030 0.970 0.000
M54.80 Other dorsalgia (Multiple sites in spine)
0.030 0.970 0.000
M54.38 Sciatica (Sacral and sacrococcygeal region)
0.030 0.970 0.000
M54.35 Sciatica (Thoracolumbar region)
0.030 0.970 0.000
M54.34 Sciatica-Thoracic
0.030 0.970 0.000
M54.33 Sciatica-Cervicothoracic
0.030 0.970 0.000
M54.32 Sciatica-Cervical
0.030 0.970 0.000
M54.31 Sciatica-Occipit-atl-axl
0.030 0.970 0.000
M54.30 Sciatica (Multiple sites in spine)
0.030 0.970 0.000
M51.8 Other specified intervertebral disk disorders
0.029 0.971 0.000
M50.0 Cervical disk disorder with myelopathy
0.029 0.971 0.000
M54.58 Low back pain (Sacral and sacrococcygeal region)
0.029 0.971 0.000
M54.36 Sciatica (Lumbar region)
0.029 0.971 0.000
M50.1 Cervical disk disorder with radiculopathy
0.028 0.971 0.000
M54.97 Dorsalgia, unspecified (Lumbosacral region)
0.028 0.972 0.000
M54.95 Dorsalgia, unspecified (Thoracolumbar region)
0.028 0.972 0.000
M54.93 Dorsalgia, unspecified (Cervicothoracic region)
0.028 0.972 0.000
M54.92 Dorsalgia, unspecified (Cervical region)
0.028 0.972 0.000
M54.91 Dorsalgia, unspecified (Occipito-atlanto-axial region)
0.028 0.972 0.000
M54.90 Dorsalgia, unspecified (Multiple sites in spine)
0.028 0.972 0.000
M54.17 Radiculopathy (Lumbosacral region)
0.028 0.972 0.000
M54.69 Pain in thoracic spine-Site unspe
0.028 0.972 0.000
M54.68 Pain in thoracic spine-Sacral/sacrococ
0.028 0.972 0.000
M54.67 Pain in thoracic spine-Lumbosacral
0.028 0.972 0.000
M54.66 Pain in thoracic spine-Lumbar
0.028 0.972 0.000
M54.65 Pain in thoracic spine (Thoracolumbar region)
0.028 0.972 0.000
M54.63 Pain in thoracic spine (Cervicothoracic region)
0.028 0.972 0.000
M54.62 Pain in thoracic spine-Cervical
0.028 0.972 0.000
M54.61 Pain in thoracic spine-Occipit-atl-axl
0.028 0.972 0.000
M54.60 Pain in thoracic spine (Multiple sites in spine)
0.028 0.972 0.000
M54.94 Dorsalgia, unspecified (Thoracic region)
0.027 0.973 0.000
M54.98 Dorsalgia, unspecified (Sacral and sacrococcygeal region)
0.027 0.973 0.000
M54.57 Low back pain (Lumbosacral region)
0.026 0.974 0.000
M54.39 Sciatica (Site unspecified)
0.025 0.975 0.000
M54.64 Pain in thoracic spine (Thoracic region)
0.024 0.975 0.000
M53.9 Dorsopathy, unspecified
0.023 0.976 0.000
M53.8 Other specified dorsopathies
0.023 0.976 0.000
M53.2 Spinal instabilities
0.023 0.976 0.000
M53.1 Cervicobrachial syndrome
0.023 0.976 0.000
M53.0 Cervicocranial syndrome
0.023 0.976 0.000
M54.55 Low back pain (Thoracolumbar region)
0.023 0.977 0.000
M54.54 Low back pain-Thoracic
0.023 0.977 0.000
M54.53 Low back pain-Cervicothoracic
0.023 0.977 0.000
M54.52 Low back pain-Cervical
0.023 0.977 0.000
M54.51 Low back pain-Occipit-atl-axl
0.023 0.977 0.000
M51.19 Lumbar and other intervertebral disc disorders with radiculopathy; site unspecified
0.022 0.977 0.000
M51.16 Intervertebral disc disorders w radiculopathy, lumbar region
0.022 0.977 0.000
M51.37 Other intervertebral disc degeneration, lumbosacral region
0.022 0.977 0.000
M53.3 Sacrococcygeal disorders, not elsewhere classified
0.021 0.979 0.000
M54.50 Low back pain (Multiple sites in spine)
0.019 0.981 0.000
M54.56 Low back pain (Lumbar region)
0.018 0.982 0.000
M53.09 Cervicocranial syndrome-Site unspe
0.017 0.983 0.000
M53.08 Cervicocranial syndrome-Sacral/sacrococ
0.017 0.983 0.000
M53.07 Cervicocranial syndrome-Lumbosacral
0.017 0.983 0.000
M53.06 Cervicocranial syndrome-Lumbar
0.017 0.983 0.000
M53.05 Cervicocranial syndrome-Thoracolumbar
0.017 0.983 0.000
M53.04 Cervicocranial syndrome-Thoracic
0.017 0.983 0.000
M53.03 Cervicocranial syndrome (Cervicothoracic region)
0.017 0.983 0.000
M53.02 Cervicocranial syndrome (Cervical region)
0.017 0.983 0.000
M53.01 Cervicocranial syndrome (Occipito-atlanto-axial region)
0.017 0.983 0.000
M53.00 Cervicocranial syndrome (Multiple sites in spine)
0.017 0.983 0.000
M53.19 Cervicobrachial syndrome-Site unspe
0.017 0.983 0.000
M53.18 Cervicobrachial syndrome-Sacral/sacrococ
0.017 0.983 0.000
M53.17 Cervicobrachial syndrome-Lumbosacral
0.017 0.983 0.000
M53.16 Cervicobrachial syndrome-Lumbar
0.017 0.983 0.000
M53.15 Cervicobrachial syndrome-Thoracolumbar
0.017 0.983 0.000
M53.14 Cervicobrachial syndrome-Thoracic
0.017 0.983 0.000
M53.13 Cervicobrachial syndrome (Cervicothoracic region)
0.017 0.983 0.000
M53.12 Cervicobrachial syndrome (Cervical region)
0.017 0.983 0.000
M53.11 Cervicobrachial syndrome (Occipito-atlanto-axial region)
0.017 0.983 0.000
M53.10 Cervicobrachial syndrome (Multiple sites in spine)
0.017 0.983 0.000
M53.29 Spinal instabilities (Site unspecified)
0.017 0.983 0.000
M53.28 Spinal instabilities (Sacral and sacrococcygeal region)
0.017 0.983 0.000
M53.27 Spinal instabilities (Lumbosacral region)
0.017 0.983 0.000
M53.26 Spinal instabilities (Lumbar region)
0.017 0.983 0.000
M53.25 Spinal instabilities (Thoracolumbar region)
0.017 0.983 0.000
M53.24 Spinal instabilities (Thoracic region)
0.017 0.983 0.000
M53.23 Spinal instabilities (Cervicothoracic region)
0.017 0.983 0.000
M53.22 Spinal instabilities (Cervical region)
0.017 0.983 0.000
M53.21 Spinal instabilities (Occipito-atlanto-axial region)
0.017 0.983 0.000
M53.20 Spinal instabilities (Multiple sites in spine)
0.017 0.983 0.000
M53.89 Other specified dorsopathies (Site unspecified)
0.017 0.983 0.000
M53.88 Other specified dorsopathies (Sacral and sacrococcygeal region)
0.017 0.983 0.000
M53.87 Other specified dorsopathies (Lumbosacral region)
0.017 0.983 0.000
M53.86 Other specified dorsopathies (Lumbar region)
0.017 0.983 0.000
M53.85 Other specified dorsopathies (Thoracolumbar region)
0.017 0.983 0.000
M53.84 Other specified dorsopathies (Thoracic region)
0.017 0.983 0.000
M53.83 Other specified dorsopathies (Cervicothoracic region)
0.017 0.983 0.000
M53.82 Other specified dorsopathies (Cervical region)
0.017 0.983 0.000
M53.81 Other specified dorsopathies (Occipito-atlanto-axial region)
0.017 0.983 0.000
M53.80 Other specified dorsopathies (Multiple sites in spine)
0.017 0.983 0.000
M53.99 Dorsopathy, unspecified (Site unspecified)
0.017 0.983 0.000
M53.98 Dorsopathy, unspecified (Sacral and sacrococcygeal region)
0.017 0.983 0.000
M53.97 Dorsopathy, unspecified (Lumbosacral region)
0.017 0.983 0.000
M53.96 Dorsopathy, unspecified (Lumbar region)
0.017 0.983 0.000
M53.95 Dorsopathy, unspecified (Thoracolumbar region)
0.017 0.983 0.000
M53.94 Dorsopathy, unspecified (Thoracic region)
0.017 0.983 0.000
M53.93 Dorsopathy, unspecified (Cervicothoracic region)
0.017 0.983 0.000
M53.92 Dorsopathy, unspecified (Cervical region)
0.017 0.983 0.000
M53.91 Dorsopathy, unspecified (Occipito-atlanto-axial region)
0.017 0.983 0.000
M53.90 Dorsopathy, unspecified (Multiple sites in spine)
0.017 0.983 0.000
M54.99 Dorsalgia, unspecified (Site unspecified)
0.017 0.983 0.000
M53.39 Sacrococcygeal disorders, not elsewhere classified-Site uns
0.015 0.985 0.000
M53.37 Sacrococcygeal disorders, not elsewhere classified-Lumbosac
0.015 0.985 0.000
M53.36 Sacrococcygeal disorders, not elsewhere classified-Lumbar
0.015 0.985 0.000
M53.35 Sacrococcygeal disorders, not elsewhere classified-Thoracol
0.015 0.985 0.000
M53.34 Sacrococcygeal disorders, not elsewhere classified-Thoracic
0.015 0.985 0.000
M53.33 Sacrococcygeal disorders, not elsewhere classified-Cervicot
0.015 0.985 0.000
M53.32 Sacrococcygeal disorders, not elsewhere classified-Cervical
0.015 0.985 0.000
M53.31 Sacrococcygeal disorders, not elsewhere classified-Occipit-
0.015 0.985 0.000
M53.30 Sacrococcygeal disorders, not elsewhere classified-Mult sit
0.015 0.985 0.000
M53.38 Sacrococcygeal disorders, not elsewhere classified-Sacral/s
0.012 0.987 0.000
B95.4 Other streptococcus as the cause of diseases classified to other chapters
0.011 0.989 0.000
M23.32 Other meniscus derangements (Posterior cruciate ligament or Posterior horn of medial meniscus)
0.008 0.992 0.000
M07.39 Other psoriatic arthropathies (Site unspecified)
0.007 0.993 0.000
M54.59 Low back pain (Site unspecified)
0.006 0.994 0.000
N85.2 Hypertrophy of uterus
0.000 0.994 0.006
M07.3 Other psoriatic arthropathies
0.006 0.994 0.000
M89.9 Disorder of bone, unspecified
0.006 0.994 0.000
M89.97 Disorder of bone, unspecified (Ankle and foot)
0.006 0.994 0.000
M89 Other disorders of bone
0.006 0.994 0.000
E66.8 Other obesity
0.006 0.994 0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.000 0.994 0.006
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.006 0.994 0.000
M86-M90 Other osteopathies
0.006 0.994 0.000
M07 Psoriatic and enteropathic arthropathies
0.005 0.995 0.000
T50.9 Other and unspecified drugs, medicaments and biological substances
0.000 0.995 0.005
M89.95 Disorder of bone, unspecified (Pelvic region and thigh)
0.005 0.995 0.000
M23.3 Other meniscus derangements
0.005 0.995 0.000
J33.0 Polyp of nasal cavity
0.000 0.995 0.005
D23.7 Skin of lower limb, including hip
0.000 0.995 0.005
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.000 0.995 0.005
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.005 0.995 0.000
M05-M14 Inflammatory polyarthropathies
0.005 0.995 0.000
M07.30 Other psoriatic arthropathies (Multiple sites)
0.005 0.995 0.000
B95.5 Unspecified streptococcus as the cause of diseases classified to other chapters
0.005 0.995 0.000
M89.0 Algoneurodystrophy
0.005 0.995 0.000
M23.30 Other meniscus derangements (Multiple sites)
0.005 0.995 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.000 0.995 0.005
M89.96 Disorder of bone, unspecified (Lower leg)
0.005 0.995 0.000
M89.98 Disorder of bone, unspecified (Other)
0.005 0.995 0.000
M90 Osteopathies in diseases classified elsewhere
0.005 0.995 0.000
M89.94 Disorder of bone, unspecified (Hand)
0.005 0.995 0.000
M07.38 Other psoriatic arthropathies (Other)
0.004 0.995 0.000
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.004 0.995 0.000
M07.36 Other psoriatic arthropathies (Lower leg)
0.004 0.995 0.000
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)
0.004 0.995 0.000
M07.34 Other psoriatic arthropathies (Hand)
0.004 0.995 0.000
M07.33 Other psoriatic arthropathies (Forearm)
0.004 0.995 0.000
M07.32 Other psoriatic arthropathies (Upper arm)
0.004 0.995 0.000
M07.31 Other psoriatic arthropathies (Shoulder region)
0.004 0.995 0.000
M89.99 Disorder of bone, unspecified (Site unspecified)
0.004 0.995 0.000
M89.93 Disorder of bone, unspecified (Forearm)
0.004 0.995 0.000
M89.92 Disorder of bone, unspecified (Upper arm)
0.004 0.995 0.000
M89.91 Disorder of bone, unspecified (Shoulder region)
0.004 0.995 0.000
M89.90 Disorder of bone, unspecified (Multiple sites)
0.004 0.995 0.000
T42.4 Benzodiazepines
0.000 0.995 0.005
M11 Other crystal arthropathies
0.005 0.995 0.000
Z12.1 Special screening examination for neoplasm of intestinal tract
0.000 0.995 0.005
M60-M63 Disorders of muscles
0.004 0.995 0.000
F41.0 Panic disorder [episodic paroxysmal anxiety]
0.000 0.995 0.005
M40-M43 Deforming dorsopathies
0.005 0.995 0.000
B95.3 Streptococcus pneumoniae as the cause of diseases classified to other chapters
0.004 0.995 0.000
M89.6 Osteopathy after poliomyelitis
0.004 0.996 0.000
M89.5 Osteolysis
0.004 0.996 0.000
M89.4 Other hypertrophic osteo-arthropathy
0.004 0.996 0.000
M89.3 Hypertrophy of bone
0.004 0.996 0.000
M89.2 Other disorders of bone development and growth
0.004 0.996 0.000
M89.1 Epiphyseal arrest
0.004 0.996 0.000
B95.7 Other staphylococcus as the cause of diseases classified to other chapters
0.004 0.996 0.000
M11.2 Other chondrocalcinosis
0.004 0.996 0.000
M23.34 Other meniscus derangements (Lateral collateral ligament or Anterior horn of lateral meniscus)
0.004 0.996 0.000
M00-M03 Infectious arthropathies
0.004 0.996 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.000 0.996 0.004
M11.26 Other chondrocalcinosis (Lower leg)
0.004 0.996 0.000
M23.39 Other meniscus derangements (Unspecified ligament or Unspecified meniscus)
0.004 0.996 0.000
M80-M85 Disorders of bone density and structure
0.004 0.996 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.004 0.996 0.000
M89.06 Algoneurodystrophy (Lower leg)
0.004 0.996 0.000
M86 Osteomyelitis
0.004 0.996 0.000
M07.6 Other enteropathic arthropathies
0.004 0.996 0.000
M07.5 Arthropathy in ulcerative colitis
0.004 0.996 0.000
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.004 0.996 0.000
M07.2 Psoriatic spondylitis
0.004 0.996 0.000
M07.1 Arthritis mutilans
0.004 0.996 0.000
M07.0 Distal interphalangeal psoriatic arthropathy
0.004 0.996 0.000
M90.7 Fracture of bone in neoplastic disease
0.004 0.996 0.000
M91-M94 Chondropathies
0.004 0.996 0.000
M23.37 Other meniscus derangements-Capsular lig
0.004 0.996 0.000
M89.8 Other specified disorders of bone
0.004 0.996 0.000
M23.33 Other meniscus derangements (Medial collateral ligament or Other and unspecified medial meniscus)
0.004 0.996 0.000
M88 Paget's disease of bone [osteitis deformans]
0.004 0.996 0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants
0.000 0.996 0.004
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified
0.000 0.996 0.004
T42.5 Mixed antiepileptics, not elsewhere classified
0.000 0.996 0.004
T42.3 Barbiturates
0.000 0.996 0.004
T42.2 Succinimides and oxazolidinediones
0.000 0.996 0.004
T42.1 Iminostilbenes
0.000 0.996 0.004
T42.0 Hydantoin derivatives
0.000 0.996 0.004
M14 Arthropathies in other diseases classified elsewhere
0.004 0.996 0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.000 0.996 0.004
M23 Internal derangement of knee
0.004 0.996 0.000
M22.4 Chondromalacia patellae
0.004 0.996 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.000 0.996 0.004
M23.31 Other meniscus derangements (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.004 0.996 0.000
M43 Other deforming dorsopathies
0.004 0.996 0.000
M12 Other specific arthropathies
0.004 0.996 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.004 0.996 0.000
M08 Juvenile arthritis
0.004 0.996 0.000
B95.1 Streptococcus, group B, as the cause of diseases classified to other chapters
0.004 0.996 0.000
M60 Myositis
0.004 0.996 0.000
M89.09 Algoneurodystrophy (Site unspecified)
0.004 0.996 0.000
M89.08 Algoneurodystrophy (Other)
0.004 0.996 0.000
M89.07 Algoneurodystrophy (Ankle and foot)
0.004 0.996 0.000
M89.05 Algoneurodystrophy (Pelvic region and thigh)
0.004 0.996 0.000
M89.04 Algoneurodystrophy (Hand)
0.004 0.996 0.000
M89.03 Algoneurodystrophy (Forearm)
0.004 0.996 0.000
M89.02 Algoneurodystrophy (Upper arm)
0.004 0.996 0.000
M89.01 Algoneurodystrophy (Shoulder region)
0.004 0.996 0.000
M89.00 Algoneurodystrophy (Multiple sites)
0.004 0.996 0.000
M90.72 Fracture of bone in neoplastic disease (Upper arm)
0.004 0.996 0.000
T50.8 Diagnostic agents
0.000 0.996 0.004
T50.7 Analeptics and opioid receptor antagonists
0.000 0.996 0.004
T50.6 Antidotes and chelating agents, not elsewhere classified
0.000 0.996 0.004
T50.5 Appetite depressants
0.000 0.996 0.004
T50.4 Drugs affecting uric acid metabolism
0.000 0.996 0.004
T50.3 Electrolytic, caloric and water-balance agents
0.000 0.996 0.004
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics
0.000 0.996 0.004
T50.1 Loop [high-ceiling] diuretics
0.000 0.996 0.004
T50.0 Mineralocorticoids and their antagonists
0.000 0.996 0.004
M22 Disorders of patella
0.004 0.996 0.000
M87 Osteonecrosis
0.004 0.996 0.000
M65-M68 Disorders of synovium and tendon
0.004 0.996 0.000
M43.2 Other fusion of spine
0.004 0.996 0.000
M90.8 Osteopathy in other diseases classified elsewhere
0.003 0.996 0.000
M90.6 Osteitis deformans in neoplastic disease
0.003 0.996 0.000
M90.5 Osteonecrosis in other diseases classified elsewhere
0.003 0.996 0.000
M90.4 Osteonecrosis due to heamoglobinopathy
0.003 0.996 0.000
M90.3 Osteonecrosis in caisson disease
0.003 0.996 0.000
M90.2 Osteopathy in other infectious diseases classified elsewhere
0.003 0.996 0.000
M90.1 Periostitis in other infectious diseases classified elsewhere
0.003 0.996 0.000
M90.0 Tuberculosis of bone
0.003 0.996 0.000
M05 Seropositive rheumatoid arthritis
0.004 0.996 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.000 0.996 0.004
M43.26 Other fusion of spine (Lumbar region)
0.004 0.996 0.000
M85 Other disorders of bone density and structure
0.004 0.996 0.000
M11.9 Crystal arthropathy, unspecified
0.003 0.996 0.000
M11.8 Other specified crystal arthropathies
0.003 0.996 0.000
M11.1 Familial chondrocalcinosis
0.003 0.996 0.000
M11.0 Hydroxyapatite deposition disease
0.003 0.996 0.000
M63 Disorders of muscle in diseases classified elsewhere
0.003 0.996 0.000
M61 Calcification and ossification of muscle
0.003 0.996 0.000
M42 Spinal osteochondrosis
0.003 0.996 0.000
M40 Kyphosis and lordosis
0.003 0.996 0.000
M62 Other disorders of muscle
0.003 0.996 0.000
O48 Prolonged pregnancy
0.000 0.996 0.004
M20-M25 Other joint disorders
0.004 0.996 0.000
B96.8 Other specified bacterial agents as the cause of diseases classified to other chapters
0.004 0.996 0.000
M90.75 Fracture of bone in neoplastic disease (Pelvic region and thigh)
0.003 0.996 0.000
M00 Pyogenic arthritis
0.003 0.997 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.000 0.997 0.003
M23.35 Other meniscus derangements (Posterior horn of lateral meniscus)
0.003 0.997 0.000
M89.19 Epiphyseal arrest (Site unspecified)
0.003 0.997 0.000
M89.18 Epiphyseal arrest (Other)
0.003 0.997 0.000
M89.17 Epiphyseal arrest (Ankle and foot)
0.003 0.997 0.000
M89.16 Epiphyseal arrest (Lower leg)
0.003 0.997 0.000
M89.15 Epiphyseal arrest (Pelvic region and thigh)
0.003 0.997 0.000
M89.14 Epiphyseal arrest (Hand)
0.003 0.997 0.000
M89.13 Epiphyseal arrest (Forearm)
0.003 0.997 0.000
M89.12 Epiphyseal arrest (Upper arm)
0.003 0.997 0.000
M89.11 Epiphyseal arrest (Shoulder region)
0.003 0.997 0.000
M89.10 Epiphyseal arrest (Multiple sites)
0.003 0.997 0.000
M89.29 Other disorders of bone development and growth (Site unspecified)
0.003 0.997 0.000
M89.28 Other disorders of bone development and growth (Other)
0.003 0.997 0.000
M89.27 Other disorders of bone development and growth (Ankle and foot)
0.003 0.997 0.000
M89.26 Other disorders of bone development and growth (Lower leg)
0.003 0.997 0.000
M89.25 Other disorders of bone development and growth (Pelvic region and thigh)
0.003 0.997 0.000
M89.24 Other disorders of bone development and growth (Hand)
0.003 0.997 0.000
M89.23 Other disorders of bone development and growth (Forearm)
0.003 0.997 0.000
M89.22 Other disorders of bone development and growth (Upper arm)
0.003 0.997 0.000
M89.21 Other disorders of bone development and growth (Shoulder region)
0.003 0.997 0.000
M89.20 Other disorders of bone development and growth (Multiple sites)
0.003 0.997 0.000
M89.39 Hypertrophy of bone (Site unspecified)
0.003 0.997 0.000
M89.38 Hypertrophy of bone (Other)
0.003 0.997 0.000
M89.37 Hypertrophy of bone (Ankle and foot)
0.003 0.997 0.000
M89.36 Hypertrophy of bone (Lower leg)
0.003 0.997 0.000
M89.35 Hypertrophy of bone (Pelvic region and thigh)
0.003 0.997 0.000
M89.34 Hypertrophy of bone (Hand)
0.003 0.997 0.000
M89.33 Hypertrophy of bone (Forearm)
0.003 0.997 0.000
M89.32 Hypertrophy of bone (Upper arm)
0.003 0.997 0.000
M89.31 Hypertrophy of bone (Shoulder region)
0.003 0.997 0.000
M89.30 Hypertrophy of bone (Multiple sites)
0.003 0.997 0.000
M89.49 Other hypertrophic osteoarthropathy (Site unspecified)
0.003 0.997 0.000
M89.48 Other hypertrophic osteoarthropathy (Other)
0.003 0.997 0.000
M89.47 Other hypertrophic osteoarthropathy (Ankle and foot)
0.003 0.997 0.000
M89.46 Other hypertrophic osteoarthropathy (Lower leg)
0.003 0.997 0.000
M89.45 Other hypertrophic osteoarthropathy (Pelvic region and thigh)
0.003 0.997 0.000
M89.44 Other hypertrophic osteoarthropathy (Hand)
0.003 0.997 0.000
M89.43 Other hypertrophic osteoarthropathy (Forearm)
0.003 0.997 0.000
M89.42 Other hypertrophic osteoarthropathy (Upper arm)
0.003 0.997 0.000
M89.41 Other hypertrophic osteoarthropathy (Shoulder region)
0.003 0.997 0.000
M89.40 Other hypertrophic osteoarthropathy (Multiple sites)
0.003 0.997 0.000
M89.59 Osteolysis (Site unspecified)
0.003 0.997 0.000
M89.58 Osteolysis (Other)
0.003 0.997 0.000
M89.57 Osteolysis (Ankle and foot)
0.003 0.997 0.000
M89.56 Osteolysis (Lower leg)
0.003 0.997 0.000
M89.55 Osteolysis (Pelvic region and thigh)
0.003 0.997 0.000
M89.54 Osteolysis (Hand)
0.003 0.997 0.000
M89.53 Osteolysis (Forearm)
0.003 0.997 0.000
M89.52 Osteolysis (Upper arm)
0.003 0.997 0.000
M89.51 Osteolysis (Shoulder region)
0.003 0.997 0.000
M89.50 Osteolysis (Multiple sites)
0.003 0.997 0.000
M89.69 Osteopathy after poliomyelitis (Site unspecified)
0.003 0.997 0.000
M89.68 Osteopathy after poliomyelitis (Other)
0.003 0.997 0.000
M89.67 Osteopathy after poliomyelitis (Ankle and foot)
0.003 0.997 0.000
M89.66 Osteopathy after poliomyelitis (Lower leg)
0.003 0.997 0.000
M89.65 Osteopathy after poliomyelitis (Pelvic region and thigh)
0.003 0.997 0.000
M89.64 Osteopathy after poliomyelitis (Hand)
0.003 0.997 0.000
M89.63 Osteopathy after poliomyelitis (Forearm)
0.003 0.997 0.000
M89.62 Osteopathy after poliomyelitis (Upper arm)
0.003 0.997 0.000
M89.61 Osteopathy after poliomyelitis (Shoulder region)
0.003 0.997 0.000
M89.60 Osteopathy after poliomyelitis (Multiple sites)
0.003 0.997 0.000
M11.29 Other chondrocalcinosis (Site unspecified)
0.003 0.997 0.000
M11.28 Other chondrocalcinosis (Other)
0.003 0.997 0.000
M11.27 Other chondrocalcinosis (Ankle and foot)
0.003 0.997 0.000
M11.25 Other chondrocalcinosis (Pelvic region and thigh)
0.003 0.997 0.000
M11.24 Other chondrocalcinosis (Hand)
0.003 0.997 0.000
M11.23 Other chondrocalcinosis (Forearm)
0.003 0.997 0.000
M11.22 Other chondrocalcinosis (Upper arm)
0.003 0.997 0.000
M11.21 Other chondrocalcinosis (Shoulder region)
0.003 0.997 0.000
M11.20 Other chondrocalcinosis (Multiple sites)
0.003 0.997 0.000
M95 Other acquired deformities of musculoskeletal system and connective tissue
0.003 0.997 0.000
M03 Postinfective and reactive arthropathies in diseases classified elsewhere
0.003 0.997 0.000
M02 Reactive arthropathies
0.003 0.997 0.000
M01 Direct infections of joint in infectious and parasitic diseases classified elsewhere
0.003 0.997 0.000
M81 Osteoporosis without pathological fracture
0.003 0.997 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.000 0.997 0.003
M06.34 Rheumatoid nodule (Hand)
0.003 0.997 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.000 0.997 0.003
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.000 0.997 0.003
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.000 0.997 0.003
T41 Poisoning by anaesthetics and therapeutic gases
0.000 0.997 0.003
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.000 0.997 0.003
T36 Poisoning by systemic antibiotics
0.000 0.997 0.003
M65.4 Radial styloid tenosynovitis [de Quervain]
0.003 0.997 0.000
M65 Synovitis and tenosynovitis
0.003 0.997 0.000
M23.5 Chronic instability of knee
0.003 0.997 0.000
T40.2 Other opioids
0.000 0.997 0.003
M41 Scoliosis
0.003 0.997 0.000
M85.8 Other specified disorders of bone density and structure
0.003 0.997 0.000
M83 Adult osteomalacia
0.003 0.997 0.000
T39.0 Salicylates
0.000 0.997 0.003
M82 Osteoporosis in diseases classified elsewhere
0.003 0.997 0.000
M99 Biomechanical lesions, not elsewhere classified
0.003 0.997 0.000
B95.8 Unspecified staphylococcus as the cause of diseases classified to other chapters
0.003 0.997 0.000
K50.1 Crohn's disease of large intestine
0.000 0.997 0.003
M92 Other juvenile osteochondrosis
0.003 0.997 0.000
M22.8 Other disorders of patella
0.003 0.997 0.000
M86.8 Other osteomyelitis
0.003 0.997 0.000
M86.6 Other chronic osteomyelitis
0.003 0.997 0.000
M86.5 Other chronic haematogenous osteomyelitis
0.003 0.997 0.000
M86.4 Chronic osteomyelitis with draining sinus
0.003 0.997 0.000
M86.3 Chronic multifocal osteomyelitis
0.003 0.997 0.000
M86.2 Subacute osteomyelitis
0.003 0.997 0.000
M86.1 Other acute osteomyelitis
0.003 0.997 0.000
M86.0 Acute haematogenous osteomyelitis
0.003 0.997 0.000
M80 Osteoporosis with pathological fracture
0.003 0.997 0.000
M07.09 Distal interphalangeal psoriatic arthropathy (Site unspecified)
0.003 0.997 0.000
M07.08 Distal interphalangeal proriatic arthropathy-Other
0.003 0.997 0.000
M07.07 Distal interphalangeal psoriatic arthropathy (Ankle and foot)
0.003 0.997 0.000
M07.06 Distal interphalangeal proriatic arthropathy-Lower leg
0.003 0.997 0.000
M07.05 Distal interphalangeal proriatic arthropathy-Pelvic/thigh
0.003 0.997 0.000
M07.04 Distal interphalangeal psoriatic arthropathy (Hand)
0.003 0.997 0.000
M07.03 Distal interphalangeal proriatic arthropathy-Forearm
0.003 0.997 0.000
M07.02 Distal interphalangeal proriatic arthropathy-Upper arm
0.003 0.997 0.000
M07.01 Distal interphalangeal proriatic arthropathy-Shldr region
0.003 0.997 0.000
M07.00 Distal interphalangeal psoriatic arthropathy (Multiple sites)
0.003 0.997 0.000
M07.19 Arthritis mutilans (Site unspecified)
0.003 0.997 0.000
M07.18 Arthritis mutilans (Other)
0.003 0.997 0.000
M07.17 Arthritis mutilans (Ankle and foot)
0.003 0.997 0.000
M07.16 Arthritis mutilans (Lower leg)
0.003 0.997 0.000
M07.15 Arthritis mutilans (Pelvic region and thigh)
0.003 0.997 0.000
M07.14 Arthritis mutilans (Hand)
0.003 0.997 0.000
M07.13 Arthritis mutilans (Forearm)
0.003 0.997 0.000
M07.12 Arthritis mutilans (Upper arm)
0.003 0.997 0.000
M07.11 Arthritis mutilans (Shoulder region)
0.003 0.997 0.000
M07.10 Arthritis mutilans (Multiple sites)
0.003 0.997 0.000
M07.29 Psoriatic spondylitis (Site unspecified)
0.003 0.997 0.000
M07.28 Psoriatic spondylitis (Other)
0.003 0.997 0.000
M07.27 Psoriatic spondylitis (Ankle and foot)
0.003 0.997 0.000
M07.26 Psoriatic spondylitis (Lower leg)
0.003 0.997 0.000
M07.25 Psoriatic spondylitis (Pelvic region and thigh)
0.003 0.997 0.000
M07.24 Psoriatic spondylitis (Hand)
0.003 0.997 0.000
M07.23 Psoriatic spondylitis (Forearm)
0.003 0.997 0.000
M07.22 Psoriatic spondylitis (Upper arm)
0.003 0.997 0.000
M07.21 Psoriatic spondylitis (Shoulder region)
0.003 0.997 0.000
M07.20 Psoriatic spondylitis (Multiple sites)
0.003 0.997 0.000
M07.49 Arthropathy in Crohn's disease [regional enteritis] (Site unspecified)
0.003 0.997 0.000
M07.48 Arthropathy in Crohn's disease [regional enteritis] (Other)
0.003 0.997 0.000
M07.47 Arthropathy in Crohn's disease [regional enteritis] (Ankle and foot)
0.003 0.997 0.000
M07.46 Arthropathy in Crohn's disease [regional enteritis] (Lower leg)
0.003 0.997 0.000
M07.45 Arthropathy in Crohn's disease [regional enteritis] (Pelvic region and thigh)
0.003 0.997 0.000
M07.44 Arthropathy in Crohn's disease [regional enteritis] (Hand)
0.003 0.997 0.000
M07.43 Arthropathy in Crohn's disease [regional enteritis] (Forearm)
0.003 0.997 0.000
M07.42 Arthropathy in Crohn's disease [regional enteritis] (Upper arm)
0.003 0.997 0.000
M07.41 Arthropathy in Crohn's disease [regional enteritis] (Shoulder region)
0.003 0.997 0.000
M07.40 Arthropathy in Crohn's disease [regional enteritis] (Multiple sites)
0.003 0.997 0.000
M07.59 Arthropathy in ulcerative colitis (Site unspecified)
0.003 0.997 0.000
M07.58 Arthropathy in ulcerative colitis (Other)
0.003 0.997 0.000
M07.57 Arthropathy in ulcerative colitis (Ankle and foot)
0.003 0.997 0.000
M07.56 Arthropathy in ulcerative colitis (Lower leg)
0.003 0.997 0.000
M07.55 Arthropathy in ulcerative colitis (Pelvic region and thigh)
0.003 0.997 0.000
M07.54 Arthropathy in ulcerative colitis (Hand)
0.003 0.997 0.000
M07.53 Arthropathy in ulcerative colitis (Forearm)
0.003 0.997 0.000
M07.52 Arthropathy in ulcerative colitis (Upper arm)
0.003 0.997 0.000
M07.51 Arthropathy in ulcerative colitis (Shoulder region)
0.003 0.997 0.000
M07.50 Arthropathy in ulcerative colitis (Multiple sites)
0.003 0.997 0.000
M07.69 Other enteropathic arthropathies (Site unspecified)
0.003 0.997 0.000
M07.68 Other enteropathic arthropathies (Other)
0.003 0.997 0.000
M07.67 Other enteropathic arthropathies (Ankle and foot)
0.003 0.997 0.000
M07.66 Other enteropathic arthropathies (Lower leg)
0.003 0.997 0.000
M07.65 Other enteropathic arthropathies (Pelvic region and thigh)
0.003 0.997 0.000
M07.64 Other enteropathic arthropathies (Hand)
0.003 0.997 0.000
M07.63 Other enteropathic arthropathies (Forearm)
0.003 0.997 0.000
M07.62 Other enteropathic arthropathies (Upper arm)
0.003 0.997 0.000
M07.61 Other enteropathic arthropathies (Shoulder region)
0.003 0.997 0.000
M07.60 Other enteropathic arthropathies (Multiple sites)
0.003 0.997 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

This website was created, designed, and edited by ORCID iD iconPatrick K. Albers

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