TreeWAS – Variant ID: rs4963128

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
H65-H75 Diseases of middle ear and mastoid	1.000	0.000	0.000
H66 Suppurative and unspecified otitis media	0.997	0.003	0.000
Chapter VIII Diseases of the ear and mastoid process	0.996	0.004	0.000
H90-H95 Other disorders of ear	0.990	0.010	0.000
H90 Conductive and sensorineural hearing loss	0.989	0.011	0.000
H74 Other disorders of middle ear and mastoid	0.983	0.017	0.000
H60-H62 Diseases of external ear	0.981	0.019	0.000
E03.9 Hypothyroidism, unspecified	0.980	0.020	0.000
H66.3 Other chronic suppurative otitis media	0.980	0.020	0.000
H90.1 Conductive hearing loss, unilateral with unrestricted hearing on the contralateral side	0.975	0.025	0.000
H73 Other disorders of tympanic membrane	0.973	0.027	0.000
H61 Other disorders of external ear	0.965	0.035	0.000
H73.8 Other specified disorders of tympanic membrane	0.943	0.057	0.000
H74.4 Polyp of middle ear	0.934	0.066	0.000
H66.9 Otitis media, unspecified	0.924	0.076	0.000
H61.2 Impacted cerumen	0.919	0.081	0.000
H61.3 Acquired stenosis of external ear canal	0.913	0.087	0.000
H74.3 Other acquired abnormalities of ear ossicles	0.911	0.089	0.000
H90.0 Conductive hearing loss, bilateral	0.900	0.100	0.000
H71 Cholesteatoma of middle ear	0.893	0.107	0.000
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified	0.889	0.111	0.000
H66.1 Chronic tubotympanic suppurative otitis media	0.887	0.113	0.000
H90.3 Sensorineural hearing loss, bilateral	0.864	0.136	0.000
H61.9 Disorder of external ear, unspecified	0.829	0.171	0.000
H73.9 Disorder of tympanic membrane, unspecified	0.828	0.172	0.000
H90.7 Mixed conductive and sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side	0.821	0.179	0.000
H66.4 Suppurative otitis media, unspecified	0.821	0.179	0.000
H95.1 Other disorders following mastoidectomy	0.818	0.182	0.000
H90.6 Mixed conductive and sensorineural hearing loss, bilateral	0.817	0.183	0.000
H90.8 Mixed conductive and sensorineural hearing loss, unspecified	0.802	0.198	0.000
H60 Otitis externa	0.787	0.213	0.000
H74.2 Discontinuity and dislocation of ear ossicles	0.781	0.219	0.000
H70 Mastoiditis and related conditions	0.770	0.230	0.000
H72 Perforation of tympanic membrane	0.762	0.238	0.000
H69 Other disorders of Eustachian tube	0.742	0.258	0.000
H65 Nonsuppurative otitis media	0.738	0.262	0.000
H74.8 Other specified disorders of middle ear and mastoid	0.736	0.264	0.000
H62 Disorders of external ear in diseases classified elsewhere	0.734	0.266	0.000
H90.4 Sensorineural hearing loss, unilateral with unrestricted hearing on the contralateral side	0.733	0.267	0.000
H72.8 Other perforations of tympanic membrane	0.721	0.279	0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere	0.717	0.283	0.000
H67 Otitis media in diseases classified elsewhere	0.717	0.283	0.000
H94 Other disorders of ear in diseases classified elsewhere	0.710	0.290	0.000
H74.1 Adhesive middle ear disease	0.707	0.293	0.000
H95.0 Recurrent cholesteatoma of postmastoidectomy cavity	0.705	0.295	0.000
H90.2 Conductive hearing loss, unspecified	0.703	0.297	0.000
H73.1 Chronic myringitis	0.700	0.299	0.000
H74.9 Disorder of middle ear and mastoid, unspecified	0.688	0.312	0.000
H68 Eustachian salpingitis and obstruction	0.678	0.322	0.000
H66.0 Acute suppurative otitis media	0.674	0.326	0.000
H61.8 Other specified disorders of external ear	0.668	0.332	0.000
H69.9 Eustachian tube disorder, unspecified	0.650	0.349	0.000
H73.0 Acute myringitis	0.645	0.355	0.000
H95.9 Postprocedural disorder of ear and mastoid process, unspecified	0.642	0.358	0.000
H70.1 Chronic mastoiditis	0.633	0.367	0.000
H65.4 Other chronic nonsuppurative otitis media	0.629	0.371	0.000
H60.3 Other infective otitis externa	0.625	0.375	0.000
H60.2 Malignant otitis externa	0.624	0.376	0.000
H60.0 Abscess of external ear	0.614	0.386	0.000
H60.1 Cellulitis of external ear	0.597	0.403	0.000
H74.0 Tympanosclerosis	0.593	0.407	0.000
H60.4 Cholesteatoma of external ear	0.589	0.411	0.000
H66.2 Chronic atticoantral suppurative otitis media	0.588	0.412	0.000
H65.2 Chronic serous otitis media	0.586	0.414	0.000
H65.0 Acute serous otitis media	0.584	0.416	0.000
H61.1 Non-infective disorders of pinna	0.580	0.420	0.000
H72.2 Other marginal perforations of tympanic membrane	0.573	0.427	0.000
H62.0 Otitis externa in bacterial diseases classified elsewhere	0.556	0.444	0.000
H70.2 Petrositis	0.552	0.448	0.000
H90.5 Sensorineural hearing loss, unspecified	0.552	0.448	0.000
H72.1 Attic perforation of tympanic membrane	0.549	0.451	0.000
H70.0 Acute mastoiditis	0.548	0.452	0.000
H70.9 Mastoiditis, unspecified	0.543	0.457	0.000
H95.8 Other postprocedural disorders of ear and mastoid process	0.532	0.468	0.000
H69.0 Patulous Eustachian tube	0.532	0.468	0.000
H60.5 Acute otitis externa, non-infective	0.526	0.474	0.000
H62.8 Other disorders of external ear in diseases classified elsewhere	0.526	0.474	0.000
H62.4 Otitis externa in other diseases classified elsewhere	0.526	0.474	0.000
H62.3 Otitis externa in other infectious and parasitic diseases classified elsewhere	0.526	0.474	0.000
H62.2 Otitis externa in mycoses	0.526	0.474	0.000
H62.1 Otitis externa in viral diseases classified elsewhere	0.526	0.474	0.000
H70.8 Other mastoiditis and related conditions	0.523	0.477	0.000
H67.8 Otitis media in other diseases classified elsewhere	0.514	0.486	0.000
H67.1 Otitis media in viral diseases classified elsewhere	0.514	0.486	0.000
H67.0 Otitis media in bacterial diseases classified elsewhere	0.514	0.486	0.000
H75.8 Other specified disorders of middle ear and mastoid in diseases classified elsewhere	0.514	0.486	0.000
H75.0 Mastoiditis in infectious and parasitic diseases classified elsewhere	0.514	0.486	0.000
H94.8 Other specified disorders of ear in diseases classified elsewhere	0.509	0.491	0.000
H94.0 Acoustic neuritis in infectious and parasitic diseases classified elsewhere	0.509	0.491	0.000
H60.9 Otitis externa, unspecified	0.498	0.502	0.000
H60.8 Other otitis externa	0.498	0.502	0.000
H68.0 Eustachian salpingitis	0.486	0.513	0.000
H92 Otalgia and effusion of ear	0.485	0.515	0.000
H61.0 Perichondritis of external ear	0.485	0.515	0.000
H65.1 Other acute nonsuppurative otitis media	0.455	0.545	0.000
H68.1 Obstruction of Eustachian tube	0.448	0.552	0.000
H65.9 Nonsuppurative otitis media, unspecified	0.442	0.558	0.000
E03 Other hypothyroidism	0.414	0.586	0.000
H92.1 Otorrhoea	0.399	0.601	0.000
H65.3 Chronic mucoid otitis media	0.386	0.614	0.000
H72.0 Central perforation of tympanic membrane	0.347	0.652	0.000
E03.8 Other specified hypothyroidism	0.345	0.655	0.000
H80-H83 Diseases of inner ear	0.335	0.664	0.000
H69.8 Other specified disorders of Eustachian tube	0.316	0.684	0.001
E03.0 Congenital hypothyroidism with diffuse goitre	0.298	0.701	0.000
E03.5 Myxoedema coma	0.297	0.703	0.000
E03.4 Atrophy of thyroid (acquired)	0.297	0.703	0.000
E03.3 Postinfectious hypothyroidism	0.297	0.703	0.000
H92.2 Otorrhagia	0.290	0.710	0.000
E03.1 Congenital hypothyroidism without goitre	0.289	0.711	0.000
H93 Other disorders of ear, not elsewhere classified	0.289	0.711	0.000
H91 Other hearing loss	0.275	0.725	0.000
H80 Otosclerosis	0.261	0.739	0.000
H82 Vertiginous syndromes in diseases classified elsewhere	0.241	0.759	0.000
H72.9 Perforation of tympanic membrane, unspecified	0.227	0.773	0.000
H93.3 Disorders of acoustic nerve	0.222	0.777	0.000
H93.2 Other abnormal auditory perceptions	0.210	0.790	0.000
H93.0 Degenerative and vascular disorders of ear	0.207	0.793	0.000
H80.0 Otosclerosis involving oval window, nonobliterative	0.207	0.793	0.000
H91.2 Sudden idiopathic hearing loss	0.199	0.801	0.000
H80.8 Other otosclerosis	0.193	0.807	0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.190	0.810	0.001
H80.2 Cochlear otosclerosis	0.187	0.813	0.000
H80.1 Otosclerosis involving oval window, obliterative	0.187	0.813	0.000
H91.8 Other specified hearing loss	0.187	0.813	0.000
H91.1 Presbycusis	0.184	0.816	0.000
H80.9 Otosclerosis, unspecified	0.180	0.820	0.000
H91.0 Ototoxic hearing loss	0.179	0.821	0.000
H91.3 Deaf mutism, not elsewhere classified	0.176	0.824	0.000
H93.8 Other specified disorders of ear	0.175	0.824	0.000
H93.9 Disorder of ear, unspecified	0.134	0.865	0.001
H83 Other diseases of inner ear	0.122	0.878	0.000
H83.3 Noise effects on inner ear	0.090	0.910	0.000
H83.1 Labyrinthine fistula	0.087	0.912	0.000
H83.9 Disease of inner ear, unspecified	0.086	0.914	0.000
H83.2 Labyrinthine dysfunction	0.084	0.916	0.000
H92.0 Otalgia	0.079	0.920	0.001
H83.8 Other specified diseases of inner ear	0.076	0.924	0.000
E00-E07 Disorders of thyroid gland	0.073	0.927	0.000
H81 Disorders of vestibular function	0.069	0.931	0.000
S01.9 Open wound of head, part unspecified	0.000	0.938	0.062
E06 Thyroiditis	0.060	0.940	0.000
E06.3 Autoimmune thyroiditis	0.055	0.945	0.000
Z87.1 Personal history of diseases of the digestive system	0.053	0.947	0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.052	0.948	0.000
E00 Congenital iodine-deficiency syndrome	0.052	0.948	0.000
E07 Other disorders of thyroid	0.051	0.948	0.000
E02 Subclinical iodine-deficiency hypothyroidism	0.051	0.949	0.000
H81.4 Vertigo of central origin	0.050	0.950	0.000
H81.3 Other peripheral vertigo	0.048	0.952	0.000
C44.5 Skin of trunk	0.000	0.952	0.048
E06.1 Subacute thyroiditis	0.046	0.954	0.000
H93.1 Tinnitus	0.044	0.956	0.000
E06.4 Drug-induced thyroiditis	0.043	0.957	0.000
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.043	0.957	0.000
E06.0 Acute thyroiditis	0.043	0.957	0.000
H81.1 Benign paroxysmal vertigo	0.041	0.958	0.000
H81.8 Other disorders of vestibular function	0.041	0.959	0.000
H81.9 Disorder of vestibular function, unspecified	0.041	0.959	0.000
E07.9 Disorder of thyroid, unspecified	0.041	0.959	0.000
E06.5 Other chronic thyroiditis	0.039	0.961	0.000
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.038	0.962	0.000
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.038	0.962	0.000
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.038	0.962	0.000
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.038	0.962	0.000
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.038	0.962	0.000
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.038	0.962	0.000
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.038	0.962	0.000
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.038	0.962	0.000
E07.1 Dyshormogenetic goitre	0.037	0.963	0.000
E07.0 Hypersecretion of calcitonin	0.037	0.963	0.000
H81.2 Vestibular neuronitis	0.037	0.963	0.000
E04 Other non-toxic goitre	0.034	0.966	0.000
E06.9 Thyroiditis, unspecified	0.034	0.966	0.000
H81.0 Meniere's disease	0.033	0.967	0.000
E07.8 Other specified disorders of thyroid	0.031	0.969	0.000
K08.8 Other specified disorders of teeth and supporting structures	0.000	0.970	0.030
E04.9 Non-toxic goitre, unspecified	0.029	0.971	0.000
E04.0 Non-toxic diffuse goitre	0.027	0.973	0.000
E04.8 Other specified non-toxic goitre	0.025	0.975	0.000
H91.9 Hearing loss, unspecified	0.022	0.978	0.000
I60.9 Subarachnoid haemorrhage, unspecified	0.017	0.983	0.000
E05 Thyrotoxicosis [hyperthyroidism]	0.016	0.984	0.000
E04.1 Non-toxic single thyroid nodule	0.014	0.986	0.000
B18.2 Chronic viral hepatitis C	0.000	0.987	0.013
H83.0 Labyrinthitis	0.012	0.988	0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.011	0.988	0.000
E05.5 Thyroid crisis or storm	0.011	0.989	0.000
E05.4 Thyrotoxicosis factitia	0.011	0.989	0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.011	0.989	0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.011	0.989	0.000
C44.3 Skin of other and unspecified parts of face	0.000	0.990	0.010
E05.8 Other thyrotoxicosis	0.010	0.990	0.000
I60 Subarachnoid haemorrhage	0.010	0.990	0.000
C44 Other malignant neoplasms of skin	0.000	0.990	0.010
C44.2 Skin of ear and external auricular canal	0.000	0.990	0.010
I60.2 Subarachnoid haemorrhage from anterior communicating artery	0.009	0.991	0.000
E04.2 Non-toxic multinodular goitre	0.009	0.991	0.000
I60.8 Other subarachnoid haemorrhage	0.009	0.991	0.000
C44.9 Malignant neoplasm of skin, unspecified	0.000	0.992	0.008
I60.3 Subarachnoid haemorrhage from posterior communicating artery	0.007	0.992	0.000
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified	0.007	0.993	0.000
I60.4 Subarachnoid haemorrhage from basilar artery	0.007	0.993	0.000
I60.5 Subarachnoid haemorrhage from vertebral artery	0.007	0.993	0.000
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation	0.007	0.993	0.000
C44.8 Overlapping lesion of skin	0.000	0.993	0.007
O68.2 Labour and delivery complicated by foetal heart rate anomaly with meconium in amniotic fluid	0.007	0.993	0.000
N95.8 Other specified menopausal and perimenopausal disorders	0.000	0.993	0.007
C44.6 Skin of upper limb, including shoulder	0.000	0.993	0.007
Z01.8 Other specified special examinations	0.000	0.993	0.007
B18 Chronic viral hepatitis	0.000	0.993	0.006
I60.6 Subarachnoid haemorrhage from other intracranial arteries	0.006	0.994	0.000
L50.9 Urticaria, unspecified	0.006	0.994	0.000
B18.8 Other chronic viral hepatitis	0.000	0.995	0.005
B18.1 Chronic viral hepatitis B without delta-agent	0.000	0.995	0.005
B18.0 Chronic viral hepatitis B with delta-agent	0.000	0.995	0.005
E05.9 Thyrotoxicosis, unspecified	0.005	0.995	0.000
S82.10 Fracture of upper end of tibia (closed)	0.005	0.995	0.000
B18.9 Chronic viral hepatitis, unspecified	0.000	0.996	0.004
I60.1 Subarachnoid haemorrhage from middle cerebral artery	0.004	0.996	0.000
Y41.8 Other specified systemic anti-infectives and antiparasitics	0.000	0.996	0.004
I42.2 Other hypertrophic cardiomyopathy	0.000	0.996	0.004
E05.0 Thyrotoxicosis with diffuse goitre	0.004	0.996	0.000
D43.2 Brain, unspecified	0.000	0.996	0.004
O64.0 Obstructed labour due to incomplete rotation of foetal head	0.003	0.996	0.000
Y41.0 Sulphonamides	0.000	0.997	0.003
M54.16 Radiculopathy (Lumbar region)	0.003	0.997	0.000
C44.0 Skin of lip	0.000	0.997	0.003
Y41 Other systemic anti-infectives and antiparasitics	0.000	0.997	0.003
M90.75 Fracture of bone in neoplastic disease (Pelvic region and thigh)	0.003	0.997	0.000
C45.0 Mesothelioma of pleura	0.003	0.997	0.000
S64.2 Injury of radial nerve at wrist and hand level	0.000	0.997	0.003
M07.30 Other psoriatic arthropathies (Multiple sites)	0.003	0.997	0.000
B37.0 Candidal stomatitis	0.003	0.997	0.000
B15-B19 Viral hepatitis	0.000	0.997	0.003
K04.8 Radicular cyst	0.003	0.997	0.000
D06.9 Cervix, unspecified	0.000	0.997	0.003
B16 Acute hepatitis B	0.000	0.997	0.003
N08.5 Glomerular disorders in systemic connective tissue disorders	0.003	0.997	0.000
Y41.1 Antimycobacterial drugs	0.000	0.997	0.003
S64.0 Injury of ulnar nerve at wrist and hand level	0.000	0.997	0.003
Y41.5 Antiviral drugs	0.000	0.997	0.003
B16.9 Acute hepatitis B without delta-agent and without hepatic coma	0.000	0.997	0.003
I42.0 Dilated cardiomyopathy	0.000	0.997	0.003
I42 Cardiomyopathy	0.000	0.997	0.003
O66.5 Failed application of vacuum extractor and forceps, unspecified	0.003	0.997	0.000
Y41.9 Systemic anti-infective and antiparasitic, unspecified	0.000	0.997	0.002
Y41.4 Anthelminthics	0.000	0.997	0.002
Y41.3 Other antiprotozoal drugs	0.000	0.997	0.002
K63.1 Perforation of intestine (nontraumatic)	0.000	0.997	0.002
Y41.2 Antimalarials and drugs acting on other blood protozoa	0.000	0.998	0.002
M89.96 Disorder of bone, unspecified (Lower leg)	0.002	0.998	0.000
I70.20 Atherosclerosis of arteries of extremities (without gangrene)	0.002	0.998	0.000
K10.8 Other specified diseases of jaws	0.000	0.998	0.002
I42.6 Alcoholic cardiomyopathy	0.000	0.998	0.002
I42.4 Endocardial fibroelastosis	0.000	0.998	0.002
M90.7 Fracture of bone in neoplastic disease	0.002	0.998	0.000
O64 Obstructed labour due to malposition and malpresentation of foetus	0.002	0.998	0.000
J33.9 Nasal polyp, unspecified	0.002	0.998	0.000
B16.2 Acute hepatitis B without delta-agent with hepatic coma	0.000	0.998	0.002
B16.1 Acute hepatitis B with delta-agent (coinfection) without hepatic coma	0.000	0.998	0.002
B16.0 Acute hepatitis B with delta-agent (coinfection) with hepatic coma	0.000	0.998	0.002
B17 Other acute viral hepatitis	0.000	0.998	0.002
I42.7 Cardiomyopathy due to drugs and other external agents	0.000	0.998	0.002
I42.1 Obstructive hypertrophic cardiomyopathy	0.000	0.998	0.002
O64.1 Obstructed labour due to breech presentation	0.002	0.998	0.000
B15 Acute hepatitis A	0.000	0.998	0.002
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system	0.000	0.998	0.002
S64 Injury of nerves at wrist and hand level	0.000	0.998	0.002
I42.3 Endomyocardial (eosinophilic) disease	0.000	0.998	0.002
L50 Urticaria	0.002	0.998	0.000
M90.72 Fracture of bone in neoplastic disease (Upper arm)	0.002	0.998	0.000
B17.1 Acute hepatitis C	0.000	0.998	0.002
D43.0 Brain, supratentorial	0.000	0.998	0.002
S64.3 Injury of digital nerve of thumb	0.000	0.998	0.002
M90.71 Fracture of bone in neoplastic disease (Shoulder region)	0.002	0.998	0.000
J35.8 Other chronic diseases of tonsils and adenoids	0.000	0.998	0.002
M89.8 Other specified disorders of bone	0.002	0.998	0.000
M21.07 Valgus deformity, not elsewhere classified (Ankle and foot)	0.002	0.998	0.000
M89.87 Other specified disorders of bone (Ankle and foot)	0.002	0.998	0.000
M89 Other disorders of bone	0.002	0.998	0.000
B19 Unspecified viral hepatitis	0.000	0.998	0.002
C44.7 Skin of lower limb, including hip	0.000	0.998	0.002
T45.5 Anticoagulants	0.002	0.998	0.000
D43.4 Spinal cord	0.000	0.998	0.002
E80.4 Gilbert's syndrome	0.000	0.998	0.002
I42.5 Other restrictive cardiomyopathy	0.000	0.998	0.002
M89.5 Osteolysis	0.002	0.998	0.000
O62.2 Other uterine inertia	0.002	0.998	0.000
G96.1 Disorders of meninges, not elsewhere classified	0.000	0.998	0.002
O64.3 Obstructed labour due to brow presentation	0.002	0.998	0.000
T45.0 Antiallergic and antiemetic drugs	0.002	0.998	0.000
M89.4 Other hypertrophic osteo-arthropathy	0.002	0.998	0.000
Z86.3 Personal history of endocrine, nutritional and metabolic diseases	0.002	0.998	0.000
M89.40 Other hypertrophic osteoarthropathy (Multiple sites)	0.002	0.998	0.000
O64.5 Obstructed labour due to compound presentation	0.002	0.998	0.000
M89.81 Other specified disorders of bone (Shoulder region)	0.002	0.998	0.000
M89.94 Disorder of bone, unspecified (Hand)	0.002	0.998	0.000
M89.89 Other specified disorders of bone (Site unspecified)	0.002	0.998	0.000
M90.79 Fracture of bone in neoplastic disease (Site unspecified)	0.002	0.998	0.000
M90.77 Fracture of bone in neoplastic disease (Ankle and foot)	0.002	0.998	0.000
M90.74 Fracture of bone in neoplastic disease (Hand)	0.002	0.998	0.000
M90.73 Fracture of bone in neoplastic disease (Forearm)	0.002	0.998	0.000
M89.0 Algoneurodystrophy	0.002	0.998	0.000
O64.4 Obstructed labour due to shoulder presentation	0.002	0.998	0.000
Z35.5 Supervision of elderly primigravida	0.002	0.998	0.000
M90.76 Fracture of bone in neoplastic disease (Lower leg)	0.002	0.998	0.000
Z88.9 Personal history of allergy to unspecified drugs, medicaments and biological substances	0.000	0.998	0.002
M89.55 Osteolysis (Pelvic region and thigh)	0.002	0.998	0.000
B17.0 Acute delta-(super) infection of hepatitis B carrier	0.000	0.998	0.002
B15.0 Hepatitis A with hepatic coma	0.000	0.998	0.002
I42.9 Cardiomyopathy, unspecified	0.000	0.998	0.002
S64.9 Injury of unspecified nerve at wrist and hand level	0.000	0.998	0.002
S64.8 Injury of other nerves at wrist and hand level	0.000	0.998	0.002
M89.84 Other specified disorders of bone (Hand)	0.002	0.998	0.000
D43.9 Central nervous system, unspecified	0.000	0.998	0.002
D43.7 Other parts of central nervous system	0.000	0.998	0.002
D43.3 Cranial nerves	0.000	0.998	0.002
S82.1 Fracture of upper end of tibia	0.002	0.998	0.000
M89.38 Hypertrophy of bone (Other)	0.002	0.998	0.000
M89.56 Osteolysis (Lower leg)	0.002	0.998	0.000
I42.8 Other cardiomyopathies	0.000	0.998	0.002
C43-C44 Melanoma and other malignant neoplasms of skin	0.000	0.998	0.002
M89.09 Algoneurodystrophy (Site unspecified)	0.002	0.998	0.000
L50.6 Contact urticaria	0.002	0.998	0.000
L50.5 Cholinergic urticaria	0.002	0.998	0.000
L50.4 Vibratory urticaria	0.002	0.998	0.000
L50.3 Dermatographic urticaria	0.002	0.998	0.000
L50.2 Urticaria due to cold and heat	0.002	0.998	0.000
N88.8 Other specified noninflammatory disorders of cervix uteri	0.002	0.998	0.000
C45 Mesothelioma	0.002	0.998	0.000
B17.8 Other specified acute viral hepatitis	0.000	0.998	0.002
M89.3 Hypertrophy of bone	0.002	0.998	0.000
M89.82 Other specified disorders of bone (Upper arm)	0.002	0.998	0.000
M89.80 Other specified disorders of bone (Multiple sites)	0.002	0.998	0.000
M89.9 Disorder of bone, unspecified	0.002	0.998	0.000
O62.4 Hypertonic, incoordinate and prolonged uterine contractions	0.002	0.998	0.000
O64.9 Obstructed labour due to malposition and malpresentation, unspecified	0.002	0.998	0.000
M89.83 Other specified disorders of bone (Forearm)	0.002	0.998	0.000
G80.9 Infantile cerebral palsy, unspecified	0.000	0.998	0.002
G95.1 Vascular myelopathies	0.000	0.998	0.002
G95.0 Syringomyelia and syringobulbia	0.000	0.998	0.002
M89.6 Osteopathy after poliomyelitis	0.002	0.998	0.000
M89.2 Other disorders of bone development and growth	0.002	0.998	0.000
M89.1 Epiphyseal arrest	0.002	0.998	0.000
S64.1 Injury of median nerve at wrist and hand level	0.000	0.998	0.002
Z75.5 Holiday relief care	0.000	0.998	0.002
B19.0 Unspecified viral hepatitis with coma	0.000	0.998	0.001
O64.8 Obstructed labour due to other malposition and malpresentation	0.002	0.998	0.000
M90 Osteopathies in diseases classified elsewhere	0.002	0.998	0.000
M89.07 Algoneurodystrophy (Ankle and foot)	0.002	0.998	0.000
B17.2 Acute hepatitis E	0.000	0.998	0.001
O62 Abnormalities of forces of labour	0.002	0.998	0.000
M89.59 Osteolysis (Site unspecified)	0.002	0.998	0.000
M89.58 Osteolysis (Other)	0.002	0.998	0.000
M89.57 Osteolysis (Ankle and foot)	0.002	0.998	0.000
M89.54 Osteolysis (Hand)	0.002	0.998	0.000
M89.53 Osteolysis (Forearm)	0.002	0.998	0.000
M89.52 Osteolysis (Upper arm)	0.002	0.998	0.000
M89.51 Osteolysis (Shoulder region)	0.002	0.998	0.000
M89.50 Osteolysis (Multiple sites)	0.002	0.998	0.000
D43.1 Brain, infratentorial	0.000	0.998	0.002
L50.8 Other urticaria	0.002	0.998	0.000
M89.03 Algoneurodystrophy (Forearm)	0.002	0.998	0.000
M89.49 Other hypertrophic osteoarthropathy (Site unspecified)	0.002	0.998	0.000
M89.48 Other hypertrophic osteoarthropathy (Other)	0.002	0.998	0.000
M89.47 Other hypertrophic osteoarthropathy (Ankle and foot)	0.002	0.998	0.000
M89.46 Other hypertrophic osteoarthropathy (Lower leg)	0.002	0.998	0.000
M89.45 Other hypertrophic osteoarthropathy (Pelvic region and thigh)	0.002	0.998	0.000
M89.44 Other hypertrophic osteoarthropathy (Hand)	0.002	0.998	0.000
M89.43 Other hypertrophic osteoarthropathy (Forearm)	0.002	0.998	0.000
M89.42 Other hypertrophic osteoarthropathy (Upper arm)	0.002	0.998	0.000
M89.41 Other hypertrophic osteoarthropathy (Shoulder region)	0.002	0.998	0.000
B15.9 Hepatitis A without hepatic coma	0.000	0.998	0.002
G95.8 Other specified diseases of spinal cord	0.000	0.998	0.002
S43.1 Dislocation of acromioclavicular joint	0.000	0.998	0.002
M90.70 Fracture of bone in neoplastic disease (Multiple sites)	0.001	0.998	0.000
O64.2 Obstructed labour due to face presentation	0.001	0.998	0.000
X63.0 Home	0.002	0.998	0.000
M89.88 Other specified disorders of bone (Other)	0.002	0.998	0.000
M89.08 Algoneurodystrophy (Other)	0.001	0.998	0.000
M89.05 Algoneurodystrophy (Pelvic region and thigh)	0.001	0.998	0.000
M89.04 Algoneurodystrophy (Hand)	0.002	0.998	0.000
M89.02 Algoneurodystrophy (Upper arm)	0.001	0.998	0.000
M89.01 Algoneurodystrophy (Shoulder region)	0.001	0.998	0.000
M89.86 Other specified disorders of bone (Lower leg)	0.002	0.998	0.000
B17.9 Acute viral hepatitis, unspecified	0.000	0.998	0.001
I70.2 Atherosclerosis of arteries of the extremities	0.002	0.998	0.000
M90.6 Osteitis deformans in neoplastic disease	0.002	0.998	0.000
S64.7 Injury of multiple nerves at wrist and hand level	0.000	0.998	0.001
O62.3 Precipitate labour	0.002	0.998	0.000
M90.61 Osteitis deformans in neoplastic disease (Shoulder region)	0.001	0.998	0.000
C45.2 Mesothelioma of pericardium	0.001	0.998	0.000
C45.1 Mesothelioma of peritoneum	0.001	0.998	0.000
I70.21 Atherosclerosis of arteries of extremities (with gangrene)	0.001	0.998	0.000
M25.81 Other specified joint disorders (Shoulder region)	0.002	0.998	0.000
M89.39 Hypertrophy of bone (Site unspecified)	0.001	0.998	0.000
M89.36 Hypertrophy of bone (Lower leg)	0.001	0.998	0.000
M89.35 Hypertrophy of bone (Pelvic region and thigh)	0.001	0.998	0.000
M89.34 Hypertrophy of bone (Hand)	0.001	0.998	0.000
M89.33 Hypertrophy of bone (Forearm)	0.001	0.998	0.000
M89.32 Hypertrophy of bone (Upper arm)	0.001	0.998	0.000
M89.31 Hypertrophy of bone (Shoulder region)	0.001	0.998	0.000
M89.30 Hypertrophy of bone (Multiple sites)	0.001	0.998	0.000
F25.9 Schizoaffective disorder, unspecified	0.000	0.998	0.002
O68 Labour and delivery complicated by foetal stress [distress]	0.002	0.998	0.000
M89.00 Algoneurodystrophy (Multiple sites)	0.001	0.998	0.000
M89.85 Other specified disorders of bone (Pelvic region and thigh)	0.001	0.998	0.000
M89.99 Disorder of bone, unspecified (Site unspecified)	0.001	0.998	0.000
M89.93 Disorder of bone, unspecified (Forearm)	0.001	0.998	0.000
M89.91 Disorder of bone, unspecified (Shoulder region)	0.001	0.998	0.000
C45.7 Mesothelioma of other sites	0.001	0.998	0.000
L51.1 Bullous erythema multiforme	0.001	0.998	0.000
M90.8 Osteopathy in other diseases classified elsewhere	0.001	0.998	0.000
S64.4 Injury of digital nerve of other finger	0.000	0.998	0.002
M89.19 Epiphyseal arrest (Site unspecified)	0.001	0.998	0.000
M89.18 Epiphyseal arrest (Other)	0.001	0.998	0.000
M89.17 Epiphyseal arrest (Ankle and foot)	0.001	0.998	0.000
M89.16 Epiphyseal arrest (Lower leg)	0.001	0.998	0.000
M89.15 Epiphyseal arrest (Pelvic region and thigh)	0.001	0.998	0.000
M89.14 Epiphyseal arrest (Hand)	0.001	0.998	0.000
M89.13 Epiphyseal arrest (Forearm)	0.001	0.998	0.000
M89.12 Epiphyseal arrest (Upper arm)	0.001	0.998	0.000
M89.11 Epiphyseal arrest (Shoulder region)	0.001	0.998	0.000
M89.10 Epiphyseal arrest (Multiple sites)	0.001	0.998	0.000
M89.29 Other disorders of bone development and growth (Site unspecified)	0.001	0.998	0.000
M89.28 Other disorders of bone development and growth (Other)	0.001	0.998	0.000
M89.27 Other disorders of bone development and growth (Ankle and foot)	0.001	0.998	0.000
M89.26 Other disorders of bone development and growth (Lower leg)	0.001	0.998	0.000
M89.25 Other disorders of bone development and growth (Pelvic region and thigh)	0.001	0.998	0.000
M89.24 Other disorders of bone development and growth (Hand)	0.001	0.998	0.000
M89.23 Other disorders of bone development and growth (Forearm)	0.001	0.998	0.000
M89.22 Other disorders of bone development and growth (Upper arm)	0.001	0.998	0.000
M89.21 Other disorders of bone development and growth (Shoulder region)	0.001	0.998	0.000
M89.20 Other disorders of bone development and growth (Multiple sites)	0.001	0.998	0.000
M89.69 Osteopathy after poliomyelitis (Site unspecified)	0.001	0.998	0.000
M89.68 Osteopathy after poliomyelitis (Other)	0.001	0.998	0.000
M89.67 Osteopathy after poliomyelitis (Ankle and foot)	0.001	0.998	0.000
M89.66 Osteopathy after poliomyelitis (Lower leg)	0.001	0.998	0.000
M89.65 Osteopathy after poliomyelitis (Pelvic region and thigh)	0.001	0.998	0.000
M89.64 Osteopathy after poliomyelitis (Hand)	0.001	0.998	0.000
M89.63 Osteopathy after poliomyelitis (Forearm)	0.001	0.998	0.000
M89.62 Osteopathy after poliomyelitis (Upper arm)	0.001	0.998	0.000
M89.61 Osteopathy after poliomyelitis (Shoulder region)	0.001	0.998	0.000
M89.60 Osteopathy after poliomyelitis (Multiple sites)	0.001	0.998	0.000
M90.5 Osteonecrosis in other diseases classified elsewhere	0.001	0.998	0.000
M90.4 Osteonecrosis due to heamoglobinopathy	0.001	0.998	0.000
M90.3 Osteonecrosis in caisson disease	0.001	0.998	0.000
M90.2 Osteopathy in other infectious diseases classified elsewhere	0.001	0.998	0.000
M90.0 Tuberculosis of bone	0.001	0.998	0.000
N35.9 Urethral stricture, unspecified	0.002	0.998	0.000
Q76.4 Other congenital malformations of spine, not associated with scoliosis	0.002	0.998	0.000
C44.4 Skin of scalp and neck	0.000	0.998	0.002
M90.1 Periostitis in other infectious diseases classified elsewhere	0.001	0.998	0.000
O62.8 Other abnormalities of forces of labour	0.001	0.998	0.000
O62.9 Abnormality of forces of labour, unspecified	0.001	0.998	0.000
O99.6 Diseases of the digestive system complicating pregnancy, childbirth and the puerperium	0.000	0.998	0.001
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)	0.001	0.998	0.000
S12.70 Multiple fractures of cervical spine (closed)	0.000	0.998	0.001
O62.1 Secondary uterine inertia	0.001	0.998	0.000
M89.06 Algoneurodystrophy (Lower leg)	0.001	0.999	0.000
M90.78 Fracture of bone in neoplastic disease (Other)	0.001	0.999	0.000
B19.9 Unspecified viral hepatitis without coma	0.000	0.999	0.001
R47.1 Dysarthria and anarthria	0.000	0.999	0.001
T23.2 Burn of second degree of wrist and hand	0.000	0.999	0.001
X51.9 Unspecified place	0.000	0.999	0.001
M90.69 Osteitis deformans in neoplastic disease (Site unspecified)	0.001	0.999	0.000
M90.68 Osteitis deformans in neoplastic disease (Other)	0.001	0.999	0.000
M90.67 Osteitis deformans in neoplastic disease (Ankle and foot)	0.001	0.999	0.000
M90.66 Osteitis deformans in neoplastic disease (Lower leg)	0.001	0.999	0.000
M90.65 Osteitis deformans in neoplastic disease (Pelvic region and thigh)	0.001	0.999	0.000
M90.64 Osteitis deformans in neoplastic disease (Hand)	0.001	0.999	0.000
M90.63 Osteitis deformans in neoplastic disease (Forearm)	0.001	0.999	0.000
M90.62 Osteitis deformans in neoplastic disease (Upper arm)	0.001	0.999	0.000
M90.60 Osteitis deformans in neoplastic disease (Multiple sites)	0.001	0.999	0.000
M07.3 Other psoriatic arthropathies	0.001	0.999	0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.001	0.999	0.000
M89.90 Disorder of bone, unspecified (Multiple sites)	0.001	0.999	0.000
W07.0 Home	0.000	0.999	0.001
M21.57 Acquired clawhand, clubhand, clawfoot and clubfoot (Ankle and foot)	0.000	0.999	0.001
S82.11 Fracture of upper end of tibia (open)	0.001	0.999	0.000
L50.1 Idiopathic urticaria	0.001	0.999	0.000
L50.0 Allergic urticaria	0.001	0.999	0.000
M07.38 Other psoriatic arthropathies (Other)	0.001	0.999	0.000
L51 Erythema multiforme	0.001	0.999	0.000
M90.84 Osteopathy in other diseases classified elsewhere (Hand)	0.001	0.999	0.000
O87.2 Haemorrhoids in the puerperium	0.001	0.999	0.000
M79.84 Other specified soft tissue disorders (Hand)	0.001	0.999	0.000
M90.09 Tuberculosis of bone (Site unspecified)	0.001	0.999	0.000
M90.08 Tuberculosis of bone (Other)	0.001	0.999	0.000
M90.07 Tuberculosis of bone (Ankle and foot)	0.001	0.999	0.000
M90.06 Tuberculosis of bone (Lower leg)	0.001	0.999	0.000
M90.05 Tuberculosis of bone (Pelvic region and thigh)	0.001	0.999	0.000
M90.04 Tuberculosis of bone (Hand)	0.001	0.999	0.000
M90.03 Tuberculosis of bone (Forearm)	0.001	0.999	0.000
M90.02 Tuberculosis of bone (Upper arm)	0.001	0.999	0.000
M90.01 Tuberculosis of bone (Shoulder region)	0.001	0.999	0.000
M90.00 Tuberculosis of bone (Multiple sites)	0.001	0.999	0.000
M90.29 Osteopathy in other infectious diseases classified elsewhere (Site unspecified)	0.001	0.999	0.000
M90.28 Osteopathy in other infectious diseases classified elsewhere (Other)	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations