TreeWAS – Variant ID: rs4974559

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
D86.9 Sarcoidosis, unspecified	0.391	0.609	0.000
D86 Sarcoidosis	0.366	0.634	0.000
D86.0 Sarcoidosis of lung	0.333	0.667	0.000
D86.8 Sarcoidosis of other and combined sites	0.328	0.672	0.000
D86.3 Sarcoidosis of skin	0.271	0.729	0.000
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes	0.265	0.735	0.000
D86.1 Sarcoidosis of lymph nodes	0.254	0.746	0.000
D80-D89 Certain disorders involving the immune mechanism	0.206	0.794	0.000
D80 Immunodeficiency with predominantly antibody defects	0.161	0.838	0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.150	0.850	0.000
D83 Common variable immunodeficiency	0.148	0.852	0.000
D82 Immunodeficiency associated with other major defects	0.148	0.852	0.000
D81 Combined immunodeficiencies	0.148	0.852	0.000
D84 Other immunodeficiencies	0.142	0.858	0.000
D80.2 Selective deficiency of immunoglobulin A [IgA]	0.128	0.872	0.000
D80.9 Immunodeficiency with predominantly antibody defects, unspecified	0.128	0.872	0.000
D80.8 Other immunodeficiencies with predominantly antibody defects	0.116	0.884	0.000
D80.7 Transient hypogammaglobulinaemia of infancy	0.116	0.884	0.000
D80.6 Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinaemia	0.116	0.884	0.000
D80.5 Immunodeficiency with increased immunoglobulin M [IgM]	0.116	0.884	0.000
D80.4 Selective deficiency of immunoglobulin M [IgM]	0.116	0.884	0.000
D80.0 Hereditary hypogammaglobulinaemia	0.116	0.884	0.000
D89.9 Disorder involving the immune mechanism, unspecified	0.114	0.886	0.000
D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses	0.112	0.888	0.000
D89.0 Polyclonal hypergammaglobulinaemia	0.111	0.889	0.000
D80.1 Nonfamilial hypogammaglobulinaemia	0.109	0.891	0.000
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified	0.108	0.892	0.000
D89.3 Immune reconstitution syndrome	0.108	0.892	0.000
D89.1 Cryoglobulinaemia	0.108	0.892	0.000
D81.9 Combined immunodeficiency, unspecified	0.106	0.894	0.000
D81.8 Other combined immunodeficiencies	0.106	0.894	0.000
D81.7 Major histocompatibility complex class II deficiency	0.106	0.894	0.000
D81.6 Major histocompatibility complex class I deficiency	0.106	0.894	0.000
D81.5 Purine nucleoside phosphorylase [PNP] deficiency	0.106	0.894	0.000
D81.4 Nezelof's syndrome	0.106	0.894	0.000
D81.3 Adenosine deaminase [ADA] deficiency	0.106	0.894	0.000
D81.2 Severe combined immunodeficiency [SCID] with low or normal B-cell numbers	0.106	0.894	0.000
D81.1 Severe combined immunodeficiency [SCID] with low T- and B-cell numbers	0.106	0.894	0.000
D81.0 Severe combined immunodeficiency [SCID] with reticular dysgenesis	0.106	0.894	0.000
D82.9 Immunodeficiency associated with major defect, unspecified	0.106	0.894	0.000
D82.8 Immunodeficiency associated with other specified major defects	0.106	0.894	0.000
D82.4 Hyperimmunoglobulin E [IgE] syndrome	0.106	0.894	0.000
D82.3 Immunodeficiency following hereditary defective response to Epstein-Barr virus	0.106	0.894	0.000
D82.2 Immunodeficiency with short-limbed stature	0.106	0.894	0.000
D82.1 Di George's syndrome	0.106	0.894	0.000
D82.0 Wiskott-Aldrich syndrome	0.106	0.894	0.000
D83.9 Common variable immunodeficiency, unspecified	0.106	0.894	0.000
D83.8 Other common variable immunodeficiencies	0.106	0.894	0.000
D83.2 Common variable immunodeficiency with autoantibodies to B- or T-cells	0.106	0.894	0.000
D83.1 Common variable immunodeficiency with predominant immunoregulatory T-cell disorders	0.106	0.894	0.000
D83.0 Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function	0.106	0.894	0.000
D84.1 Defects in the complement system	0.104	0.895	0.000
D84.8 Other specified immunodeficiencies	0.102	0.898	0.000
D84.0 Lymphocyte function antigen-1 [LFA-1] defect	0.102	0.898	0.000
D89.2 Hypergammaglobulinaemia, unspecified	0.100	0.900	0.000
D84.9 Immunodeficiency, unspecified	0.093	0.907	0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.062	0.938	0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.060	0.940	0.000
D68 Other coagulation defects	0.055	0.945	0.000
D66 Hereditary factor VIII deficiency	0.051	0.948	0.000
D69 Purpura and other haemorrhagic conditions	0.050	0.950	0.000
D68.8 Other specified coagulation defects	0.049	0.951	0.000
D68.6 Other Thrombophilia	0.047	0.953	0.000
D69.5 Secondary thrombocytopenia	0.047	0.953	0.000
D67 Hereditary factor IX deficiency	0.046	0.953	0.000
D68.5 Primary Thrombophilia	0.044	0.956	0.000
D69.0 Allergic purpura	0.043	0.957	0.000
D50-D53 Nutritional anaemias	0.043	0.957	0.000
D68.4 Acquired coagulation factor deficiency	0.042	0.958	0.000
D68.2 Hereditary deficiency of other clotting factors	0.041	0.959	0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]	0.041	0.959	0.000
D68.0 Von Willebrand's disease	0.040	0.960	0.000
D69.9 Haemorrhagic condition, unspecified	0.039	0.961	0.000
D51 Vitamin B12 deficiency anaemia	0.039	0.961	0.000
J84.1 Other interstitial pulmonary diseases with fibrosis	0.038	0.962	0.000
D68.9 Coagulation defect, unspecified	0.038	0.962	0.000
D68.1 Hereditary factor XI deficiency	0.038	0.962	0.000
D69.8 Other specified haemorrhagic conditions	0.036	0.964	0.000
D69.2 Other nonthrombocytopenic purpura	0.036	0.964	0.000
D69.1 Qualitative platelet defects	0.036	0.964	0.000
D69.4 Other primary thrombocytopenia	0.035	0.965	0.000
D51.9 Vitamin B12 deficiency anaemia, unspecified	0.035	0.965	0.000
D53 Other nutritional anaemias	0.034	0.966	0.000
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency	0.030	0.970	0.000
D69.3 Idiopathic thrombocytopenic purpura	0.029	0.971	0.000
D55-D59 Haemolytic anaemias	0.029	0.971	0.000
D68.3 Haemorrhagic disorder due to circulating anticoagulants	0.028	0.971	0.000
D52 Folate deficiency anaemia	0.028	0.972	0.000
S01 Open wound of head	0.028	0.972	0.000
S01.2 Open wound of nose	0.028	0.972	0.000
D51.8 Other vitamin B12 deficiency anaemias	0.028	0.972	0.000
D51.3 Other dietary vitamin B12 deficiency anaemia	0.028	0.972	0.000
D51.2 Transcobalamin II deficiency	0.028	0.972	0.000
D51.1 Vitamin B12 deficiency anaemia due to selective vitamin B12 malabsorption with proteinuria	0.028	0.972	0.000
D53.9 Nutritional anaemia, unspecified	0.028	0.972	0.000
S01.5 Open wound of lip and oral cavity	0.027	0.973	0.000
S01.3 Open wound of ear	0.026	0.974	0.000
D53.8 Other specified nutritional anaemias	0.024	0.975	0.000
D53.2 Scorbutic anaemia	0.024	0.975	0.000
D53.1 Other megaloblastic anaemias, not elsewhere classified	0.024	0.975	0.000
D53.0 Protein deficiency anaemia	0.024	0.975	0.000
S01.1 Open wound of eyelid and periocular area	0.024	0.976	0.000
S01.9 Open wound of head, part unspecified	0.024	0.976	0.000
S00-S09 Injuries to the head	0.024	0.976	0.000
S02 Fracture of skull and facial bones	0.024	0.976	0.000
S02.6 Fracture of mandible	0.021	0.979	0.000
S02.8 Fractures of other skull and facial bones	0.021	0.979	0.000
D57 Sickle-cell disorders	0.021	0.979	0.000
D55 Anaemia due to enzyme disorders	0.021	0.979	0.000
S02.4 Fracture of malar and maxillary bones	0.021	0.979	0.000
D52.8 Other folate deficiency anaemias	0.020	0.980	0.000
D52.1 Drug-induced folate deficiency anaemia	0.020	0.980	0.000
D52.0 Dietary folate deficiency anaemia	0.020	0.980	0.000
D70-D77 Other diseases of blood and blood-forming organs	0.020	0.980	0.000
S00 Superficial injury of head	0.020	0.980	0.000
S02.60 Fracture of mandible (closed)	0.020	0.980	0.000
S02.80 Fractures of other skull and facial bones (closed)	0.020	0.980	0.000
D56 Thalassaemia	0.019	0.981	0.000
S02.5 Fracture of tooth	0.019	0.981	0.000
D60-D64 Aplastic and other anaemias	0.019	0.981	0.000
S03 Dislocation, sprain and strain of joints and ligaments of head	0.019	0.981	0.000
S01.4 Open wound of cheek and temporomandibular area	0.018	0.981	0.000
S02.0 Fracture of vault of skull	0.018	0.981	0.000
S02.1 Fracture of base of skull	0.018	0.981	0.000
S00.0 Superficial injury of scalp	0.018	0.982	0.000
S02.40 Fracture of malar and maxillary bones (closed)	0.018	0.982	0.000
S09 Other and unspecified injuries of head	0.018	0.982	0.000
S00.1 Contusion of eyelid and periocular area	0.018	0.982	0.000
D52.9 Folate deficiency anaemia, unspecified	0.018	0.982	0.000
S08 Traumatic amputation of part of head	0.018	0.982	0.000
S07 Crushing injury of head	0.018	0.982	0.000
S04 Injury of cranial nerves	0.018	0.982	0.000
S06 Intracranial injury	0.017	0.983	0.000
D58 Other hereditary haemolytic anaemias	0.017	0.983	0.001
D75 Other diseases of blood and blood-forming organs	0.017	0.983	0.000
S05 Injury of eye and orbit	0.017	0.983	0.000
D59 Acquired haemolytic anaemia	0.016	0.984	0.001
S00.2 Other superficial injuries of eyelid and periocular area	0.016	0.984	0.000
S02.50 Fracture of tooth (closed)	0.016	0.984	0.000
S00.4 Superficial injury of ear	0.016	0.984	0.000
S02.9 Fracture of skull and facial bones, part unspecified	0.016	0.984	0.000
S02.61 Fracture of mandible (open)	0.015	0.984	0.000
S02.7 Multiple fractures involving skull and facial bones	0.015	0.984	0.000
S02.2 Fracture of nasal bones	0.016	0.984	0.000
S02.81 Fractures of other skull and facial bones (open)	0.015	0.984	0.000
D55.9 Anaemia due to enzyme disorder, unspecified	0.015	0.985	0.000
D55.8 Other anaemias due to enzyme disorders	0.015	0.985	0.000
D55.3 Anaemia due to disorders of nucleotide metabolism	0.015	0.985	0.000
D55.2 Anaemia due to disorders of glycolytic enzymes	0.015	0.985	0.000
D55.1 Anaemia due to other disorders of glutathione metabolism	0.015	0.985	0.000
D55.0 Anaemia due to glucose-6-phosphate dehydrogenase [G6PD] deficiency	0.015	0.985	0.000
D57.8 Other sickle-cell disorders	0.015	0.985	0.000
D57.3 Sickle-cell trait	0.015	0.985	0.000
D57.2 Double heterozygous sickling disorders	0.015	0.985	0.000
D57.1 Sickle-cell anaemia without crisis	0.015	0.985	0.000
D57.0 Sickle-cell anaemia with crisis	0.015	0.985	0.000
D75.1 Secondary polycythaemia	0.015	0.985	0.000
S00.5 Superficial injury of lip and oral cavity	0.015	0.985	0.000
S02.41 Fracture of malar and maxillary bones (open)	0.015	0.985	0.000
D74 Methaemoglobinaemia	0.015	0.985	0.000
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere	0.015	0.985	0.000
D71 Functional disorders of polymorphonuclear neutrophils	0.015	0.985	0.000
S02.00 Fracture of vault of skull (closed)	0.015	0.985	0.000
S03.2 Dislocation of tooth	0.015	0.985	0.000
S02.10 Fracture of base of skull (closed)	0.015	0.985	0.000
S00.3 Superficial injury of nose	0.014	0.985	0.000
S06.8 Other intracranial injuries	0.014	0.986	0.000
D56.9 Thalassaemia, unspecified	0.014	0.986	0.000
D56.8 Other thalassaemias	0.014	0.986	0.000
D56.4 Hereditary persistence of foetal haemoglobin [HPFH]	0.014	0.986	0.000
D56.2 Delta-beta thalassaemia	0.014	0.986	0.000
D56.1 Beta thalassaemia	0.014	0.986	0.000
D56.0 Alpha thalassaemia	0.014	0.986	0.000
S06.3 Focal brain injury	0.014	0.986	0.000
S02.51 Fracture of tooth (open)	0.014	0.986	0.000
T79.6 Traumatic ischaemia of muscle	0.000	0.986	0.014
S09.8 Other specified injuries of head	0.014	0.986	0.000
S06.1 Traumatic cerebral oedema	0.014	0.986	0.000
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system	0.014	0.986	0.000
S02.3 Fracture of orbital floor	0.014	0.986	0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]	0.014	0.986	0.000
D75.2 Essential thrombocytosis	0.014	0.986	0.000
D61 Other aplastic anaemias	0.014	0.986	0.000
S03.5 Sprain and strain of joints and ligaments of other and unspecified parts of head	0.013	0.986	0.000
S03.4 Sprain and strain of jaw	0.013	0.986	0.000
S03.3 Dislocation of other and unspecified parts of head	0.013	0.986	0.000
S03.1 Dislocation of septal cartilage of nose	0.013	0.986	0.000
S03.0 Dislocation of jaw	0.013	0.986	0.000
S02.01 Fracture of vault of skull (open)	0.013	0.986	0.000
S02.11 Fracture of base of skull (open)	0.013	0.986	0.000
S01.7 Multiple open wounds of head	0.013	0.986	0.000
D73 Diseases of spleen	0.014	0.986	0.000
S05.9 Injury of eye and orbit, part unspecified	0.013	0.987	0.000
S05.3 Ocular laceration without prolapse or loss of intraocular tissue	0.013	0.987	0.000
S06.6 Traumatic subarachnoid haemorrhage	0.013	0.987	0.000
S09.7 Multiple injuries of head	0.013	0.987	0.000
S09.2 Traumatic rupture of ear drum	0.013	0.987	0.000
S09.1 Injury of muscle and tendon of head	0.013	0.987	0.000
D75.0 Familial erythrocytosis	0.013	0.987	0.000
S06.9 Intracranial injury, unspecified	0.013	0.987	0.000
S09.0 Injury of blood vessels of head, not elsewhere classified	0.013	0.987	0.000
S04.9 Injury of unspecified cranial nerve	0.013	0.987	0.000
S04.8 Injury of other cranial nerves	0.013	0.987	0.000
S04.7 Injury of accessory nerve	0.013	0.987	0.000
S04.6 Injury of acoustic nerve	0.013	0.987	0.000
S04.5 Injury of facial nerve	0.013	0.987	0.000
S04.4 Injury of abducent nerve	0.013	0.987	0.000
S04.3 Injury of trigeminal nerve	0.013	0.987	0.000
S04.2 Injury of trochlear nerve	0.013	0.987	0.000
S04.1 Injury of oculomotor nerve	0.013	0.987	0.000
S04.0 Injury of optic nerve and pathways	0.013	0.987	0.000
S07.9 Crushing injury of head, part unspecified	0.013	0.987	0.000
S07.8 Crushing injury of other parts of head	0.013	0.987	0.000
S07.1 Crushing injury of skull	0.013	0.987	0.000
S07.0 Crushing injury of face	0.013	0.987	0.000
S08.9 Traumatic amputation of unspecified part of head	0.013	0.987	0.000
S08.8 Traumatic amputation of other parts of head	0.013	0.987	0.000
S08.1 Traumatic amputation of ear	0.013	0.987	0.000
S08.0 Avulsion of scalp	0.013	0.987	0.000
S05.6 Penetrating wound of eyeball without foreign body	0.013	0.987	0.000
S06.7 Intracranial injury with prolonged coma	0.012	0.987	0.000
S02.21 Fracture of nasal bones (open)	0.012	0.987	0.000
D58.8 Other specified hereditary haemolytic anaemias	0.012	0.987	0.001
D58.2 Other haemoglobinopathies	0.012	0.987	0.001
D58.1 Hereditary elliptocytosis	0.012	0.987	0.001
S09.9 Unspecified injury of head	0.013	0.987	0.000
D56.3 Thalassaemia trait	0.012	0.988	0.001
S06.80 Other intracranial injuries (without open intracranial wound)	0.012	0.988	0.000
S05.0 Injury of conjunctiva and corneal abrasion without mention of foreign body	0.012	0.988	0.000
S05.7 Avulsion of eye	0.012	0.988	0.000
S05.5 Penetrating wound of eyeball with foreign body	0.012	0.988	0.000
S05.4 Penetrating wound of orbit with or without foreign body	0.012	0.988	0.000
D59.9 Acquired haemolytic anaemia, unspecified	0.011	0.988	0.001
D59.8 Other acquired haemolytic anaemias	0.011	0.988	0.001
D59.6 Haemoglobinuria due to haemolysis from other external causes	0.011	0.988	0.001
D59.5 Paroxysmal nocturnal haemoglobinuria [Marchiafava-Micheli]	0.011	0.988	0.001
D59.4 Other nonautoimmune haemolytic anaemias	0.011	0.988	0.001
D59.3 Haemolytic-uraemic syndrome	0.011	0.988	0.001
D59.2 Drug-induced nonautoimmune haemolytic anaemia	0.011	0.988	0.001
D59.0 Drug-induced autoimmune haemolytic anaemia	0.011	0.988	0.001
D75.9 Disease of blood and blood-forming organs, unspecified	0.012	0.988	0.000
S06.30 Focal brain injury (without open intracranial wound)	0.012	0.988	0.000
S06.10 Traumatic cerebral oedema (without open intracranial wound)	0.012	0.988	0.000
S02.91 Fracture of skull and facial bones, part unspecified (open)	0.011	0.988	0.000
S02.71 Multiple fractures involving skull and facial bones (open)	0.011	0.988	0.000
S01.8 Open wound of other parts of head	0.011	0.989	0.000
D58.0 Hereditary spherocytosis	0.011	0.989	0.001
S05.8 Other injuries of eye and orbit	0.011	0.989	0.000
S05.2 Ocular laceration and rupture with prolapse or loss of intraocular tissue	0.011	0.989	0.000
D73.1 Hypersplenism	0.011	0.989	0.000
S06.4 Epidural haemorrhage	0.011	0.989	0.000
Z29.2 Other prophylactic chemotherapy	0.000	0.989	0.011
S00.7 Multiple superficial injuries of head	0.011	0.989	0.000
D74.9 Methaemoglobinaemia, unspecified	0.011	0.989	0.000
D74.8 Other methaemoglobinaemias	0.011	0.989	0.000
D74.0 Congenital methaemoglobinaemia	0.011	0.989	0.000
D73.4 Cyst of spleen	0.011	0.989	0.000
D62 Acute posthaemorrhagic anaemia	0.011	0.989	0.000
S06.5 Traumatic subdural haemorrhage	0.011	0.989	0.000
D58.9 Hereditary haemolytic anaemia, unspecified	0.010	0.989	0.001
S06.81 Other intracranial injuries (with open intracranial wound)	0.010	0.989	0.000
S06.31 Focal brain injury (with open intracranial wound)	0.010	0.990	0.000
S06.60 Traumatic subarachnoid haemorrhage (without open intracranial wound)	0.010	0.990	0.000
S06.0 Concussion	0.010	0.990	0.000
S06.11 Traumatic cerebral oedema (with open intracranial wound)	0.010	0.990	0.000
D76.2 Haemophagocytic syndrome, infection-associated	0.010	0.990	0.000
D76.1 Haemophagocytic lymphohistiocytosis	0.010	0.990	0.000
D76.0 Langerhans' cell histiocytosis, not elsewhere classified	0.010	0.990	0.000
S02.31 Fracture of orbital floor (open)	0.010	0.990	0.000
D72 Other disorders of white blood cells	0.010	0.990	0.000
D60.9 Acquired pure red cell aplasia, unspecified	0.010	0.990	0.000
D60.8 Other acquired pure red cell aplasias	0.010	0.990	0.000
D60.1 Transient acquired pure red cell aplasia	0.010	0.990	0.000
D60.0 Chronic acquired pure red cell aplasia	0.010	0.990	0.000
D61.8 Other specified aplastic anaemias	0.010	0.990	0.000
D61.3 Idiopathic aplastic anaemia	0.010	0.990	0.000
D61.2 Aplastic anaemia due to other external agents	0.010	0.990	0.000
D61.1 Drug-induced aplastic anaemia	0.010	0.990	0.000
D61.0 Constitutional aplastic anaemia	0.010	0.990	0.000
D73.3 Abscess of spleen	0.010	0.990	0.000
S06.90 Intracranial injury, unspecified (without open intracranial wound)	0.010	0.990	0.000
D73.9 Disease of spleen, unspecified	0.010	0.990	0.000
D73.2 Chronic congestive splenomegaly	0.010	0.990	0.000
D61.9 Aplastic anaemia, unspecified	0.010	0.990	0.000
S06.2 Diffuse brain injury	0.010	0.990	0.000
S02.90 Fracture of skull and facial bones, part unspecified (closed)	0.010	0.990	0.000
S06.61 Traumatic subarachnoid haemorrhage (with open intracranial wound)	0.010	0.990	0.000
S02.70 Multiple fractures involving skull and facial bones (closed)	0.009	0.990	0.000
D73.5 Infarction of spleen	0.010	0.990	0.000
S06.91 Intracranial injury, unspecified (with open intracranial wound)	0.009	0.990	0.000
D76.3 Other histiocytosis syndromes	0.009	0.990	0.000
D63 Anaemia in chronic diseases classified elsewhere	0.009	0.991	0.000
S06.71 Intracranial injury with prolonged coma (with open intracranial wound)	0.009	0.991	0.000
S06.70 Intracranial injury with prolonged coma (without open intracranial wound)	0.009	0.991	0.000
Z29 Need for other prophylactic measures	0.000	0.991	0.009
Z29.0 Isolation	0.000	0.991	0.009
D69.6 Thrombocytopenia, unspecified	0.009	0.991	0.000
S01.0 Open wound of scalp	0.009	0.991	0.000
T79 Certain early complications of trauma, not elsewhere classified	0.000	0.991	0.009
S05.1 Contusion of eyeball and orbital tissues	0.008	0.991	0.000
D73.8 Other diseases of spleen	0.008	0.991	0.000
J84 Other interstitial pulmonary diseases	0.008	0.991	0.000
T79.3 Post-traumatic wound infection, not elsewhere classified	0.000	0.992	0.008
S06.41 Epidural haemorrhage (with open intracranial wound)	0.008	0.992	0.000
D64 Other anaemias	0.008	0.992	0.000
S06.51 Traumatic subdural haemorrhage (with open intracranial wound)	0.008	0.992	0.000
D73.0 Hyposplenism	0.008	0.992	0.000
S00.8 Superficial injury of other parts of head	0.008	0.992	0.000
S06.01 Concussion (with open intracranial wound)	0.007	0.992	0.000
D75.8 Other specified diseases of blood and blood-forming organs	0.007	0.992	0.000
D72.9 Disorder of white blood cells, unspecified	0.007	0.992	0.000
D72.0 Genetic anomalies of leukocytes	0.007	0.992	0.000
Z29.1 Prophylactic immunotherapy	0.000	0.992	0.008
S02.20 Fracture of nasal bones (closed)	0.007	0.993	0.000
D59.1 Other autoimmune haemolytic anaemias	0.007	0.993	0.001
S06.21 Diffuse brain injury (with open intracranial wound)	0.007	0.993	0.000
Z49.0 Preparatory care for dialysis	0.000	0.993	0.007
S00.9 Superficial injury of head, part unspecified	0.007	0.993	0.000
Z29.8 Other specified prophylactic measures	0.000	0.993	0.007
D63.1 Anaemia in other chronic diseases classified elsewhere	0.007	0.993	0.000
Z29.9 Prophylactic measure, unspecified	0.000	0.993	0.007
S02.30 Fracture of orbital floor (closed)	0.006	0.993	0.000
D63.0 Anaemia in neoplastic disease	0.007	0.993	0.000
Z49.1 Extracorporeal dialysis	0.000	0.993	0.007
D72.8 Other specified disorders of white blood cells	0.006	0.993	0.000
S06.40 Epidural haemorrhage (without open intracranial wound)	0.006	0.994	0.000
T79.9 Unspecified early complication of trauma	0.000	0.994	0.006
T79.4 Traumatic shock	0.000	0.994	0.006
T79.2 Traumatic secondary and recurrent haemorrhage	0.000	0.994	0.006
T79.1 Fat embolism (traumatic)	0.000	0.994	0.006
T79.0 Air embolism (traumatic)	0.000	0.994	0.006
J84.0 Alveolar and parietoalveolar conditions	0.006	0.994	0.000
Z49 Care involving dialysis	0.000	0.994	0.006
T79.8 Other early complications of trauma	0.000	0.994	0.006
T79.5 Traumatic anuria	0.000	0.994	0.006
D64.8 Other specified anaemias	0.006	0.994	0.000
D64.4 Congenital dyserythropoietic anaemia	0.006	0.994	0.000
D64.3 Other sideroblastic anaemias	0.006	0.994	0.000
D64.2 Secondary sideroblastic anaemia due to drugs and toxins	0.006	0.994	0.000
D64.1 Secondary sideroblastic anaemia due to disease	0.006	0.994	0.000
D64.0 Hereditary sideroblastic anaemia	0.006	0.994	0.000
S06.50 Traumatic subdural haemorrhage (without open intracranial wound)	0.006	0.994	0.000
C77.5 Intrapelvic lymph nodes	0.000	0.994	0.006
S06.00 Concussion (without open intracranial wound)	0.005	0.995	0.000
Z49.2 Other dialysis	0.000	0.995	0.005
E27.4 Other and unspecified adrenocortical insufficiency	0.005	0.995	0.000
J84.8 Other specified interstitial pulmonary diseases	0.005	0.995	0.000
L98.0 Pyogenic granuloma	0.005	0.995	0.000
C77.4 Inguinal and lower limb lymph nodes	0.000	0.995	0.005
D72.1 Eosinophilia	0.004	0.995	0.001
T79.7 Traumatic subcutaneous emphysema	0.000	0.995	0.004
S06.20 Diffuse brain injury (without open intracranial wound)	0.004	0.995	0.000
K05.3 Chronic periodontitis	0.000	0.995	0.005
R27.0 Ataxia, unspecified	0.000	0.996	0.004
E27.8 Other specified disorders of adrenal gland	0.004	0.996	0.000
E27 Other disorders of adrenal gland	0.004	0.996	0.000
I95.2 Hypotension due to drugs	0.004	0.996	0.000
M41.96 Scoliosis, unspecified (Lumbar region)	0.000	0.996	0.004
H21.5 Other adhesions and disruptions of iris and ciliary body	0.004	0.996	0.000
M50.3 Other cervical disk degeneration	0.000	0.996	0.004
T79-T79 Certain early complications of trauma	0.000	0.996	0.004
J84.9 Interstitial pulmonary disease, unspecified	0.003	0.997	0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes	0.000	0.997	0.003
D37.0 Lip, oral cavity and pharynx	0.003	0.997	0.000
H21 Other disorders of iris and ciliary body	0.003	0.997	0.000
H21.8 Other specified disorders of iris and ciliary body	0.003	0.997	0.000
E27.2 Addisonian crisis	0.003	0.997	0.000
C77.8 Lymph nodes of multiple regions	0.000	0.997	0.003
E27.9 Disorder of adrenal gland, unspecified	0.003	0.997	0.000
E27.5 Adrenomedullary hyperfunction	0.003	0.997	0.000
E27.0 Other adrenocortical overactivity	0.003	0.997	0.000
N18.5 Chronic kidney disease, stage 5	0.000	0.997	0.003
H21.0 Hyphaema	0.003	0.997	0.000
E27.3 Drug-induced adrenocortical insufficiency	0.003	0.997	0.000
K05.1 Chronic gingivitis	0.000	0.997	0.003
E27.1 Primary adrenocortical insufficiency	0.003	0.997	0.000
K05 Gingivitis and periodontal diseases	0.000	0.997	0.003
D63.8 Anaemia in other chronic diseases classified elsewhere	0.003	0.997	0.000
M77.02 Medial epicondylitis (Upper arm)	0.000	0.997	0.003
R29.8 Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems	0.003	0.997	0.000
H21.4 Pupillary membranes	0.003	0.997	0.000
D50 Iron deficiency anaemia	0.003	0.997	0.000
Y40.0 Penicillins	0.003	0.997	0.000
Z90.3 Acquired absence of part of stomach	0.003	0.997	0.000
M07.39 Other psoriatic arthropathies (Site unspecified)	0.003	0.997	0.000
H21.1 Other vascular disorders of iris and ciliary body	0.003	0.997	0.000
C85.1 B-cell lymphoma, unspecified	0.000	0.997	0.003
H21.9 Disorder of iris and ciliary body, unspecified	0.003	0.997	0.000
Z00.0 General medical examination	0.003	0.997	0.000
C77.1 Intrathoracic lymph nodes	0.000	0.997	0.003
H21.3 Cyst of iris, ciliary body and anterior chamber	0.003	0.997	0.000
H21.2 Degeneration of iris and ciliary body	0.003	0.997	0.000
Y40.9 Systemic antibiotic, unspecified	0.003	0.997	0.000
Y40.5 Aminoglycosides	0.003	0.997	0.000
K05.6 Periodontal disease, unspecified	0.000	0.997	0.003
C18.0 Caecum	0.000	0.997	0.003
T78.2 Anaphylactic shock, unspecified	0.002	0.998	0.000
Y40 Systemic antibiotics	0.002	0.998	0.000
K05.2 Acute periodontitis	0.000	0.998	0.002
K05.5 Other periodontal diseases	0.000	0.998	0.002
K05.4 Periodontosis	0.000	0.998	0.002
C77.2 Intra-abdominal lymph nodes	0.000	0.998	0.002
D50.1 Sideropenic dysphagia	0.002	0.998	0.000
M50.2 Other cervical disk displacement	0.000	0.998	0.002
K05.0 Acute gingivitis	0.000	0.998	0.002
Y40.1 Cefalosporins and other -lactam antibiotics	0.002	0.998	0.000
R22.4 Localised swelling, mass and lump, lower limb	0.002	0.998	0.000
M54.39 Sciatica (Site unspecified)	0.002	0.998	0.000
C18.2 Ascending colon	0.000	0.998	0.002
T43.0 Tricyclic and tetracyclic antidepressants	0.000	0.998	0.002
Y52.5 Other antihypertensive drugs, not elsewhere classified	0.002	0.998	0.000
Y40.6 Rifamycins	0.002	0.998	0.000
M07.3 Other psoriatic arthropathies	0.002	0.998	0.000
Y40.7 Antifungal antibiotics, systemically used	0.002	0.998	0.000
Y40.4 Tetracyclines	0.002	0.998	0.000
Y40.2 Chloramphenicol group	0.002	0.998	0.000
M50 Cervical disk disorders	0.000	0.998	0.002
K05.22 Aggressive periodontitis, generalized	0.000	0.998	0.002
N60.8 Other benign mammary dysplasias	0.002	0.998	0.000
Y88.3 Sequelae of surgical and medical procedures as the cause of abnormal reaction of the patient or of later complication, without mention of misadventure at the time of the procedure	0.000	0.998	0.002
M19.95 Arthrosis, unspecified (Pelvic region and thigh)	0.002	0.998	0.000
H65.9 Nonsuppurative otitis media, unspecified	0.002	0.998	0.000
M67.8 Other specified disorders of synovium and tendon	0.000	0.998	0.002
Z57.2 Occupational exposure to dust	0.000	0.998	0.002
R27 Other lack of coordination	0.000	0.998	0.002
N60.2 Fibroadenosis of breast	0.002	0.998	0.000
M67.2 Synovial hypertrophy, not elsewhere classified	0.000	0.998	0.002
Y40.3 Macrolides	0.002	0.998	0.000
T78.4 Allergy, unspecified	0.002	0.998	0.000
C77.0 Lymph nodes of head, face and neck	0.000	0.998	0.002
T78.1 Other adverse food reactions, not elsewhere classified	0.002	0.998	0.000
M85.89 Other specified disorders of bone density and structure (Site unspecified)	0.002	0.998	0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases	0.000	0.998	0.002
M07.36 Other psoriatic arthropathies (Lower leg)	0.002	0.998	0.000
C80.0 Malignant neoplasm, primary site unknown, so stated	0.000	0.998	0.002
M07.30 Other psoriatic arthropathies (Multiple sites)	0.002	0.998	0.000
D03.5 Melanoma in situ of trunk	0.002	0.998	0.000
Y52.2 Other antidysrhythmic drugs, not elsewhere classified	0.002	0.998	0.000
M07.38 Other psoriatic arthropathies (Other)	0.002	0.998	0.000
M07.37 Other psoriatic arthropathies (Ankle and foot)	0.002	0.998	0.000
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)	0.002	0.998	0.000
M07.34 Other psoriatic arthropathies (Hand)	0.002	0.998	0.000
M07.33 Other psoriatic arthropathies (Forearm)	0.002	0.998	0.000
M07.32 Other psoriatic arthropathies (Upper arm)	0.002	0.998	0.000
M07.31 Other psoriatic arthropathies (Shoulder region)	0.002	0.998	0.000
M50.8 Other cervical disk disorders	0.000	0.998	0.002
C77.9 Lymph node, unspecified	0.000	0.998	0.002
M50.9 Cervical disk disorder, unspecified	0.000	0.998	0.002
T45.0 Antiallergic and antiemetic drugs	0.000	0.998	0.002
B02.9 Zoster without complication	0.000	0.998	0.002
Z94.8 Other transplanted organ and tissue status	0.000	0.998	0.002
F03 Unspecified dementia	0.002	0.998	0.000
J80-J84 Other respiratory diseases principally affecting the interstitium	0.002	0.998	0.000
E05.9 Thyrotoxicosis, unspecified	0.000	0.998	0.002
R27.8 Other and unspecified lack of coordination	0.000	0.998	0.002
R87.6 Abnormal cytological findings	0.000	0.998	0.002
M77.0 Medial epicondylitis	0.000	0.998	0.002
Q24.8 Other specified congenital malformations of heart	0.002	0.998	0.000
O26.9 Pregnancy-related condition, unspecified	0.000	0.998	0.002
Z28 Immunisation not carried out	0.000	0.998	0.001
Z27 Need for immunisation against combinations of infectious diseases	0.000	0.998	0.001
Z26 Need for immunisation against other single infectious diseases	0.000	0.998	0.001
Z25 Need for immunisation against other single viral diseases	0.000	0.998	0.001
Z24 Need for immunisation against certain single viral diseases	0.000	0.998	0.001
Z23 Need for immunisation against single bacterial diseases	0.000	0.998	0.001
T78 Adverse effects, not elsewhere classified	0.002	0.998	0.000
M50.0 Cervical disk disorder with myelopathy	0.000	0.998	0.002
F06.7 Mild cognitive disorder	0.002	0.998	0.000
M41.9 Scoliosis, unspecified	0.000	0.998	0.002
L29.9 Pruritus, unspecified	0.002	0.998	0.000
N60.3 Fibrosclerosis of breast	0.002	0.998	0.000
N95.0 Postmenopausal bleeding	0.002	0.998	0.000
H40.0 Glaucoma suspect	0.000	0.998	0.002
O69.1 Labour and delivery complicated by cord around neck, with compression	0.000	0.998	0.001
S90.9 Superficial injury of ankle and foot, unspecified	0.000	0.998	0.001
Y52.7 Peripheral vasodilators	0.001	0.998	0.000
M67 Other disorders of synovium and tendon	0.000	0.998	0.002
Z20 Contact with and exposure to communicable diseases	0.000	0.998	0.001
C80 Malignant neoplasm without specification of site	0.000	0.999	0.001
M41.95 Scoliosis, unspecified (Thoracolumbar region)	0.000	0.999	0.001
I21.1 Acute transmural myocardial infarction of inferior wall	0.000	0.999	0.001
Y40.8 Other systemic antibiotics	0.001	0.999	0.000
S82.31 Fracture of lower end of tibia (open)	0.001	0.999	0.000
Y52 Agents primarily affecting the cardiovascular system	0.001	0.999	0.000
M77.09 Medial epicondylitis (Site unspecified)	0.000	0.999	0.001
M77.08 Medial epicondylitis-Other	0.000	0.999	0.001
M77.07 Medial epicondylitis-Ankle/Foot	0.000	0.999	0.001
M77.06 Medial epicondylitis (Lower leg)	0.000	0.999	0.001
M77.05 Medial epicondylitis (Pelvic region and thigh)	0.000	0.999	0.001
M77.04 Medial epicondylitis-Hand	0.000	0.999	0.001
M77.03 Medial epicondylitis-Forearm	0.000	0.999	0.001
M77.01 Medial epicondylitis-Shldr region	0.000	0.999	0.001
M77.00 Medial epicondylitis (Multiple sites)	0.000	0.999	0.001
Z21 Asymptomatic human immunodeficiency virus [HIV] infection status	0.000	0.999	0.001
T78.9 Adverse effect, unspecified	0.001	0.999	0.000
T78.8 Other adverse effects, not elsewhere classified	0.001	0.999	0.000
Z23.8 Need for immunisation against other single bacterial diseases	0.000	0.999	0.001
Z23.7 Need for immunisation against pertussis alone	0.000	0.999	0.001
Z23.6 Need for immunisation against diphtheria alone	0.000	0.999	0.001
Z23.5 Need for immunisation against tetanus alone	0.000	0.999	0.001

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations