TreeWAS – Variant ID: rs4979462

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
# Top node	0.355	0.645
Chapter V Mental and behavioural disorders	0.345	0.655
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.344	0.656
Chapter VII Diseases of the eye and adnexa	0.332	0.668
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.330	0.670
F10-F19 Mental and behavioural disorders due to psychoactive substance use	0.321	0.679
F30-F39 Mood [affective] disorders	0.317	0.683
Chapter II Neoplasms	0.316	0.684
M15-M19 Arthrosis	0.306	0.694
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.303	0.697
H30-H36 Disorders of choroid and retina	0.299	0.700
D50-D53 Nutritional anaemias	0.296	0.704
F32 Depressive episode	0.296	0.704
Chapter XII Diseases of the skin and subcutaneous tissue	0.294	0.706
Chapter XIV Diseases of the genitourinary system	0.292	0.708
F10 Mental and behavioural disorders due to use of alcohol	0.292	0.708
M05-M14 Inflammatory polyarthropathies	0.290	0.710
Chapter XV Pregnancy, childbirth and the puerperium	0.286	0.714
D60-D64 Aplastic and other anaemias	0.283	0.716
F32.9 Depressive episode, unspecified	0.282	0.718
M17 Gonarthrosis [arthrosis of knee]	0.278	0.722
D10-D36 Benign neoplasms	0.277	0.723
H35 Other retinal disorders	0.275	0.725
M20-M25 Other joint disorders	0.274	0.726
D50 Iron deficiency anaemia	0.273	0.727
Chapter VIII Diseases of the ear and mastoid process	0.272	0.728
F17 Mental and behavioural disorders due to use of tobacco	0.266	0.734
Chapter XX External causes of morbidity and mortality	0.265	0.735
M40-M43 Deforming dorsopathies	0.265	0.735
Chapter I Certain infectious and parasitic diseases	0.265	0.735
S00-S09 Injuries to the head	0.264	0.736
M17.9 Gonarthrosis, unspecified	0.260	0.740
F10.0 Acute intoxication	0.259	0.741
H53-H54 Visual disturbances and blindness	0.259	0.741
M50-M54 Other dorsopathies	0.257	0.743
Chapter XXII Codes for special purposes	0.255	0.745
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.255	0.745
Chapter XVI Certain conditions originating in the perinatal period	0.255	0.745
M70-M79 Other soft tissue disorders	0.254	0.746
M80-M85 Disorders of bone density and structure	0.253	0.747
H00-H06 Disorders of eyelid, lacrimal system and orbit	0.253	0.747
M65-M68 Disorders of synovium and tendon	0.252	0.747
H25-H28 Disorders of lens	0.252	0.748
D64 Other anaemias	0.251	0.749
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction	0.250	0.749
L80-L99 Other disorders of the skin and subcutaneous tissue	0.249	0.751
C64-C68 Malignant neoplasms of urinary tract	0.249	0.751
F99-F99 Unspecified mental disorder	0.248	0.752
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.248	0.752
F80-F89 Disorders of psychological development	0.248	0.752
F70-F79 Mental retardation	0.248	0.752
F60-F69 Disorders of adult personality and behaviour	0.248	0.752
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.248	0.752
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.248	0.752
F00-F09 Organic, including symptomatic, mental disorders	0.248	0.752
C60-C63 Malignant neoplasms of male genital organs	0.247	0.753
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.246	0.753
M91-M94 Chondropathies	0.246	0.753
M86-M90 Other osteopathies	0.246	0.753
M60-M63 Disorders of muscles	0.246	0.753
M00-M03 Infectious arthropathies	0.246	0.753
H35.3 Degeneration of macula and posterior pole	0.245	0.755
F40-F48 Neurotic, stress-related and somatoform disorders	0.242	0.757
F10.3 Withdrawal state	0.242	0.758
M45-M49 Spondylopathies	0.241	0.758
D50.9 Iron deficiency anaemia, unspecified	0.239	0.761
M13 Other arthritis	0.239	0.761
D00-D09 In situ neoplasms	0.238	0.762
H55-H59 Other disorders of eye and adnexa	0.238	0.762
H46-H48 Disorders of optic nerve and visual pathways	0.238	0.762
H43-H45 Disorders of vitreous body and globe	0.238	0.762
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.238	0.762
H10-H13 Disorders of conjunctiva	0.238	0.762
N30-N39 Other diseases of urinary system	0.238	0.762
D80-D89 Certain disorders involving the immune mechanism	0.236	0.763
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.236	0.763
D55-D59 Haemolytic anaemias	0.236	0.763
Chapter VI Diseases of the nervous system	0.234	0.766
D50.8 Other iron deficiency anaemias	0.233	0.767
S09 Other and unspecified injuries of head	0.232	0.768
N80-N98 Noninflammatory disorders of female genital tract	0.232	0.768
M18 Arthrosis of first carpometacarpal joint	0.231	0.769
L60-L75 Disorders of skin appendages	0.231	0.769
Chapter XI Diseases of the digestive system	0.231	0.769
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances	0.230	0.770
F18 Mental and behavioural disorders due to use of volatile solvents	0.230	0.770
F16 Mental and behavioural disorders due to use of hallucinogens	0.230	0.770
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine	0.230	0.770
F14 Mental and behavioural disorders due to use of cocaine	0.230	0.770
F13 Mental and behavioural disorders due to use of sedatives or hypnotics	0.230	0.770
F12 Mental and behavioural disorders due to use of cannabinoids	0.230	0.770
F11 Mental and behavioural disorders due to use of opioids	0.230	0.770
D25 Leiomyoma of uterus	0.229	0.771
M06 Other rheumatoid arthritis	0.229	0.771
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites	0.228	0.772
H35.8 Other specified retinal disorders	0.228	0.772
H40-H42 Glaucoma	0.227	0.772
F38 Other mood [affective] disorders	0.227	0.773
F34 Persistent mood [affective] disorders	0.227	0.773
F33 Recurrent depressive disorder	0.227	0.773
F31 Bipolar affective disorder	0.227	0.773
F30 Manic episode	0.227	0.773
F39 Unspecified mood [affective] disorder	0.227	0.773
D64.9 Anaemia, unspecified	0.227	0.773
D37-D48 Neoplasms of uncertain or unknown behaviour	0.227	0.773
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.227	0.773
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.227	0.773
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.227	0.773
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.227	0.773
C51-C58 Malignant neoplasms of female genital organs	0.227	0.773
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.227	0.773
C40-C41 Malignant neoplasms of bone and articular cartilage	0.227	0.773
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.227	0.773
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.227	0.773
F17.1 Harmful use	0.226	0.774
D70-D77 Other diseases of blood and blood-forming organs	0.225	0.775
C15-C26 Malignant neoplasms of digestive organs	0.224	0.776
O60-O75 Complications of labour and delivery	0.224	0.776
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.223	0.777
N25-N29 Other disorders of kidney and ureter	0.222	0.778
N17-N19 Renal failure	0.221	0.779
H33 Retinal detachments and breaks	0.221	0.779
S80-S89 Injuries to the knee and lower leg	0.221	0.779
M15 Polyarthrosis	0.219	0.781
D17 Benign lipomatous neoplasm	0.219	0.781
D23 Other benign neoplasms of skin	0.218	0.782
M17.0 Primary gonarthrosis, bilateral	0.218	0.782
N10-N16 Renal tubulo-interstitial diseases	0.217	0.783
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.217	0.783
T79-T79 Certain early complications of trauma	0.217	0.783
T66-T78 Other and unspecified effects of external causes	0.217	0.783
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.217	0.783
T36-T50 Poisoning by drugs, medicaments and biological substances	0.217	0.783
T33-T35 Frostbite	0.217	0.783
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.217	0.783
T26-T28 Burns and corrosions confined to eye and internal organs	0.217	0.783
T20-T25 Burns and corrosions of external body surface, specified by site	0.217	0.783
T15-T19 Effects of foreign body entering through natural orifice	0.217	0.783
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.217	0.783
T00-T07 Injuries involving multiple body regions	0.217	0.783
S90-S99 Injuries to the ankle and foot	0.217	0.783
S70-S79 Injuries to the hip and thigh	0.217	0.783
S40-S49 Injuries to the shoulder and upper arm	0.217	0.783
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.217	0.783
S20-S29 Injuries to the thorax	0.217	0.783
S10-S19 Injuries to the neck	0.217	0.783
M20 Acquired deformities of fingers and toes	0.217	0.783
D22 Melanocytic naevi	0.217	0.783
S60-S69 Injuries to the wrist and hand	0.216	0.784
C43-C44 Melanoma and other malignant neoplasms of skin	0.216	0.784
M19 Other arthrosis	0.216	0.784
F10.2 Dependence syndrome	0.216	0.784
H60-H62 Diseases of external ear	0.215	0.785
H36 Retinal disorders in diseases classified elsewhere	0.215	0.785
H34 Retinal vascular occlusions	0.215	0.785
H32 Chorioretinal disorders in diseases classified elsewhere	0.215	0.785
H31 Other disorders of choroid	0.215	0.785
H30 Chorioretinal inflammation	0.215	0.785
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems	0.214	0.785
D53 Other nutritional anaemias	0.213	0.787
D52 Folate deficiency anaemia	0.213	0.787
D51 Vitamin B12 deficiency anaemia	0.213	0.787
O20-O29 Other maternal disorders predominantly related to pregnancy	0.212	0.787
F32.8 Other depressive episodes	0.212	0.788
F32.3 Severe depressive episode with psychotic symptoms	0.212	0.788
F32.2 Severe depressive episode without psychotic symptoms	0.212	0.788
F32.1 Moderate depressive episode	0.212	0.788
F32.0 Mild depressive episode	0.212	0.788
D27 Benign neoplasm of ovary	0.212	0.788
Chapter IV Endocrine, nutritional and metabolic diseases	0.212	0.788
H26 Other cataract	0.211	0.789
L50-L54 Urticaria and erythema	0.211	0.789
L40-L45 Papulosquamous disorders	0.211	0.789
L20-L30 Dermatitis and eczema	0.211	0.789
L10-L14 Bullous disorders	0.211	0.789
M16 Coxarthrosis [arthrosis of hip]	0.211	0.789
A00-A09 Intestinal infectious diseases	0.210	0.790
N99-N99 Other disorders of the genitourinary system	0.210	0.790
N60-N64 Disorders of breast	0.210	0.790
N00-N08 Glomerular diseases	0.210	0.790
S09.9 Unspecified injury of head	0.209	0.790
F10.9 Unspecified mental and behavioural disorder	0.209	0.791
F10.8 Other mental and behavioural disorders	0.209	0.791
F10.7 Residual and late-onset psychotic disorder	0.209	0.791
F10.6 Amnesic syndrome	0.209	0.791
F10.5 Psychotic disorder	0.209	0.791
F10.4 Withdrawal state with delirium	0.209	0.791
M43 Other deforming dorsopathies	0.209	0.791
S50-S59 Injuries to the elbow and forearm	0.209	0.791
Y60-Y69 Misadventures to patients during surgical and medical care	0.208	0.791
M14 Arthropathies in other diseases classified elsewhere	0.208	0.792
M12 Other specific arthropathies	0.208	0.792
M11 Other crystal arthropathies	0.208	0.792
M10 Gout	0.208	0.792
M09 Juvenile arthritis in diseases classified elsewhere	0.208	0.792
M08 Juvenile arthritis	0.208	0.792
M07 Psoriatic and enteropathic arthropathies	0.208	0.792
M05 Seropositive rheumatoid arthritis	0.208	0.792
H53 Visual disturbances	0.207	0.793
M23 Internal derangement of knee	0.206	0.794
W00-W19 Falls	0.205	0.794
O94-O99 Other obstetric conditions, not elsewhere classified	0.205	0.795
O85-O92 Complications predominantly related to the puerperium	0.205	0.795
O80-O84 Delivery	0.205	0.795
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.205	0.795
O00-O08 Pregnancy with abortive outcome	0.205	0.795
K50-K52 Noninfective enteritis and colitis	0.205	0.795
C50-C50 Malignant neoplasm of breast	0.205	0.795
N39 Other disorders of urinary system	0.204	0.796
D63 Anaemia in chronic diseases classified elsewhere	0.203	0.796
D61 Other aplastic anaemias	0.203	0.796
D60 Acquired pure red cell aplasia [erythroblastopenia]	0.203	0.796
D62 Acute posthaemorrhagic anaemia	0.203	0.796
M13.9 Arthritis, unspecified	0.203	0.797
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue	0.202	0.798
N70-N77 Inflammatory diseases of female pelvic organs	0.202	0.798
D18 Haemangioma and lymphangioma, any site	0.201	0.799
L91 Hypertrophic disorders of skin	0.201	0.799
C67 Malignant neoplasm of bladder	0.201	0.799
S00 Superficial injury of head	0.200	0.799
N92 Excessive, frequent and irregular menstruation	0.200	0.800
M17.5 Other secondary gonarthrosis	0.200	0.800
M17.4 Other secondary gonarthrosis, bilateral	0.200	0.800
M17.3 Other posttraumatic gonarthrosis	0.200	0.800
M17.2 Posttraumatic gonarthrosis, bilateral	0.200	0.800
M54 Dorsalgia	0.199	0.801
D36 Benign neoplasm of other and unspecified sites	0.199	0.801
D35 Benign neoplasm of other and unspecified endocrine glands	0.199	0.801
D33 Benign neoplasm of brain and other parts of central nervous system	0.199	0.801
D32 Benign neoplasm of meninges	0.199	0.801
D31 Benign neoplasm of eye and adnexa	0.199	0.801
D30 Benign neoplasm of urinary organs	0.199	0.801
D29 Benign neoplasm of male genital organs	0.199	0.801
D28 Benign neoplasm of other and unspecified female genital organs	0.199	0.801
D26 Other benign neoplasms of uterus	0.199	0.801
D21 Other benign neoplasms of connective and other soft tissue	0.199	0.801
D20 Benign neoplasm of soft tissue of retroperitoneum and peritoneum	0.199	0.801
D19 Benign neoplasm of mesothelial tissue	0.199	0.801
D16 Benign neoplasm of bone and articular cartilage	0.199	0.801
D15 Benign neoplasm of other and unspecified intrathoracic organs	0.199	0.801
D14 Benign neoplasm of middle ear and respiratory system	0.199	0.801
D13 Benign neoplasm of other and ill-defined parts of digestive system	0.199	0.801
D11 Benign neoplasm of major salivary glands	0.199	0.801
D10 Benign neoplasm of mouth and pharynx	0.199	0.801
D34 Benign neoplasm of thyroid gland	0.199	0.801
D24 Benign neoplasm of breast	0.199	0.801
M25 Other joint disorders, not elsewhere classified	0.197	0.803
H35.9 Retinal disorder, unspecified	0.197	0.803
H35.7 Separation of retinal layers	0.197	0.803
H35.6 Retinal haemorrhage	0.197	0.803
H35.5 Hereditary retinal dystrophy	0.197	0.803
H35.4 Peripheral retinal degeneration	0.197	0.803
H35.2 Other proliferative retinopathy	0.197	0.803
H35.1 Retinopathy of prematurity	0.197	0.803
H35.0 Background retinopathy and retinal vascular changes	0.197	0.803
C61 Malignant neoplasm of prostate	0.197	0.803
L82 Seborrhoeic keratosis	0.197	0.803
N40-N51 Diseases of male genital organs	0.197	0.803
M36 Systemic disorders of connective tissue in diseases classified elsewhere	0.197	0.803
M35 Other systemic involvement of connective tissue	0.197	0.803
M34 Systemic sclerosis	0.197	0.803
M33 Dermatopolymyositis	0.197	0.803
M32 Systemic lupus erythematosus	0.197	0.803
M31 Other necrotising vasculopathies	0.197	0.803
M30 Polyarteritis nodosa and related conditions	0.197	0.803
M24 Other specific joint derangements	0.197	0.803
M22 Disorders of patella	0.197	0.803
M21 Other acquired deformities of limbs	0.197	0.803
L00-L08 Infections of the skin and subcutaneous tissue	0.196	0.804
M75 Shoulder lesions	0.196	0.804
D50.1 Sideropenic dysphagia	0.196	0.804
D50.0 Iron deficiency anaemia secondary to blood loss (chronic)	0.196	0.804
F10.1 Harmful use	0.195	0.804
H80-H83 Diseases of inner ear	0.195	0.805
H65-H75 Diseases of middle ear and mastoid	0.195	0.805
H02 Other disorders of eyelid	0.194	0.806
H52 Disorders of refraction and accommodation	0.192	0.808
Chapter XXI Factors influencing health status and contact with health services	0.192	0.808
H90-H95 Other disorders of ear	0.191	0.809
F17.9 Unspecified mental and behavioural disorder	0.191	0.809
F17.8 Other mental and behavioural disorders	0.191	0.809
F17.7 Residual and late-onset psychotic disorder	0.191	0.809
F17.6 Amnesic syndrome	0.191	0.809
F17.5 Psychotic disorder	0.191	0.809
F17.4 Withdrawal state with delirium	0.191	0.809
F17.3 Withdrawal state	0.191	0.809
F17.2 Dependence syndrome	0.191	0.809
F17.0 Acute intoxication	0.191	0.809
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.190	0.809
Y85-Y89 Sequelae of external causes of morbidity and mortality	0.190	0.809
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.190	0.809
Y35-Y36 Legal intervention and operations of war	0.190	0.809
Y10-Y34 Event of undetermined intent	0.190	0.809
Y00-Y09 Assault	0.190	0.809
X85-X99 Assault	0.190	0.809
X60-X84 Intentional self-harm	0.190	0.809
X58-X59 Accidental exposure to other and unspecified factors	0.190	0.809
X50-X57 Overexertion, travel and privation	0.190	0.809
X40-X49 Accidental poisoning by and exposure to noxious substances	0.190	0.809
X30-X39 Exposure to forces of nature	0.190	0.809
X20-X29 Contact with venomous animals and plants	0.190	0.809
X10-X19 Contact with heat and hot substances	0.190	0.809
X00-X09 Exposure to smoke, fire and flames	0.190	0.809
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.190	0.809
W75-W84 Other accidental threats to breathing	0.190	0.809
W65-W74 Accidental drowning and submersion	0.190	0.809
W50-W64 Exposure to animate mechanical forces	0.190	0.809
W20-W49 Exposure to inanimate mechanical forces	0.190	0.809
V98-V99 Other and unspecified transport accidents	0.190	0.809
V95-V97 Air and space transport accidents	0.190	0.809
V90-V94 Water transport accidents	0.190	0.809
V80-V89 Other land transport accidents	0.190	0.809
V70-V79 Bus occupant injured in transport accident	0.190	0.809
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.190	0.809
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.190	0.809
V40-V49 Car occupant injured in transport accident	0.190	0.809
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.190	0.809
V20-V29 Motorcycle rider injured in transport accident	0.190	0.809
V10-V19 Pedal cyclist injured in transport accident	0.190	0.809
V01-V09 Pedestrian injured in transport accident	0.190	0.809
M42 Spinal osteochondrosis	0.190	0.810
M41 Scoliosis	0.190	0.810
M40 Kyphosis and lordosis	0.190	0.810
B99-B99 Other infectious diseases	0.190	0.810
B90-B94 Sequelae of infectious and parasitic diseases	0.190	0.810
B85-B89 Pediculosis, acariasis and other infestations	0.190	0.810
B65-B83 Helminthiases	0.190	0.810
B50-B64 Protozoal diseases	0.190	0.810
B35-B49 Mycoses	0.190	0.810
B20-B24 Human immunodeficiency virus [HIV] disease	0.190	0.810
B15-B19 Viral hepatitis	0.190	0.810
B00-B09 Viral infections characterized by skin and mucous membrane lesions	0.190	0.810
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.190	0.810
A80-A89 Viral infections of the central nervous system	0.190	0.810
A75-A79 Rickettsioses	0.190	0.810
A70-A74 Other diseases caused by chlamydiae	0.190	0.810
A65-A69 Other spirochaetal diseases	0.190	0.810
A50-A64 Infections with a predominantly sexual mode of transmission	0.190	0.810
A30-A49 Other bacterial diseases	0.190	0.810
A20-A28 Certain zoonotic bacterial diseases	0.190	0.810
A15-A19 Tuberculosis	0.190	0.810
S08 Traumatic amputation of part of head	0.190	0.810
S07 Crushing injury of head	0.190	0.810
S06 Intracranial injury	0.190	0.810
S05 Injury of eye and orbit	0.190	0.810
S04 Injury of cranial nerves	0.190	0.810
S03 Dislocation, sprain and strain of joints and ligaments of head	0.190	0.810
S02 Fracture of skull and facial bones	0.190	0.810
S01 Open wound of head	0.190	0.810
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.189	0.811
L97 Ulcer of lower limb, not elsewhere classified	0.188	0.812
M81 Osteoporosis without pathological fracture	0.188	0.812
M65 Synovitis and tenosynovitis	0.187	0.813
D17.2 Benign lipomatous neoplasm of skin and subcutaneous tissue of limbs	0.187	0.813
B25-B34 Other viral diseases	0.186	0.813
D25.9 Leiomyoma of uterus, unspecified	0.187	0.813
M72 Fibroblastic disorders	0.186	0.814
L72 Follicular cysts of skin and subcutaneous tissue	0.186	0.814
H54 Blindness and low vision	0.186	0.814
M06.9 Rheumatoid arthritis, unspecified	0.185	0.815
K80-K87 Disorders of gallbladder, biliary tract and pancreas	0.184	0.816
M53 Other dorsopathies, not elsewhere classified	0.184	0.816
M50 Cervical disk disorders	0.184	0.816
H00 Hordeolum and chalazion	0.184	0.816
K65-K67 Diseases of peritoneum	0.183	0.817
P90-P96 Other disorders originating in the perinatal period	0.183	0.817
P80-P83 Conditions involving the integument and temperature regulation of fetus and newborn	0.183	0.817
P75-P78 Digestive system disorders of fetus and newborn	0.183	0.817
P70-P74 Transitory endocrine and metabolic disorders specific to fetus and newborn	0.183	0.817
P50-P61 Haemorrhagic and haematological disorders of fetus and newborn	0.183	0.817
P35-P39 Infections specific to the perinatal period	0.183	0.817
P20-P29 Respiratory and cardiovascular disorders specific to the perinatal period	0.183	0.817
P10-P15 Birth trauma	0.183	0.817
P05-P08 Disorders related to length of gestation and fetal growth	0.183	0.817
P00-P04 Fetus and newborn affected by maternal factors and by complications of pregnancy, labour and delivery	0.183	0.817
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.183	0.817
Q80-Q89 Other congenital malformations	0.183	0.817
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.183	0.817
Q60-Q64 Congenital malformations of the urinary system	0.183	0.817
Q50-Q56 Congenital malformations of genital organs	0.183	0.817
Q38-Q45 Other congenital malformations of the digestive system	0.183	0.817
Q35-Q37 Cleft lip and cleft palate	0.183	0.817
Q30-Q34 Congenital malformations of the respiratory system	0.183	0.817
Q20-Q28 Congenital malformations of the circulatory system	0.183	0.817
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.183	0.817
Q00-Q07 Congenital malformations of the nervous system	0.183	0.817
U82-U85 Resistance to antimicrobial and antineoplastic drugs	0.183	0.817
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use	0.183	0.817
N94 Pain and other conditions associated with female genital organs and menstrual cycle	0.183	0.817
D05 Carcinoma in situ of breast	0.182	0.817
M77 Other enthesopathies	0.182	0.818
M76 Enthesopathies of lower limb, excluding foot	0.182	0.818
M73 Soft tissue disorders in diseases classified elsewhere	0.182	0.818
M71 Other bursopathies	0.182	0.818
M70 Soft tissue disorders related to use, overuse and pressure	0.182	0.818
H26.9 Cataract, unspecified	0.182	0.818
M85 Other disorders of bone density and structure	0.181	0.819
M84 Disorders of continuity of bone	0.181	0.819
M83 Adult osteomalacia	0.181	0.819
M82 Osteoporosis in diseases classified elsewhere	0.181	0.819
M80 Osteoporosis with pathological fracture	0.181	0.819
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere	0.181	0.819
H05 Disorders of orbit	0.181	0.819
H04 Disorders of lachrymal system	0.181	0.819
H03 Disorders of eyelid in diseases classified elsewhere	0.181	0.819
H01 Other inflammation of eyelid	0.181	0.819
M68 Disorders of synovium and tendon in diseases classified elsewhere	0.181	0.819
M67 Other disorders of synovium and tendon	0.181	0.819
M66 Spontaneous rupture of synovium and tendon	0.181	0.819
H28 Cataract and other disorders of lens in diseases classified elsewhere	0.181	0.819
H27 Other disorders of lens	0.181	0.819
B95-B98 Bacterial, viral and other infectious agents	0.181	0.819
N20-N23 Urolithiasis	0.181	0.819
D64.8 Other specified anaemias	0.180	0.820
D64.4 Congenital dyserythropoietic anaemia	0.180	0.820
D64.3 Other sideroblastic anaemias	0.180	0.820
D64.2 Secondary sideroblastic anaemia due to drugs and toxins	0.180	0.820
D64.1 Secondary sideroblastic anaemia due to disease	0.180	0.820
D64.0 Hereditary sideroblastic anaemia	0.180	0.820
H51 Other disorders of binocular movement	0.180	0.820
H50 Other strabismus	0.180	0.820
H49 Paralytic strabismus	0.180	0.820
K52 Other non-infective gastro-enteritis and colitis	0.180	0.820
L99 Other disorders of skin and subcutaneous tissue in diseases classified elsewhere	0.179	0.821
L95 Vasculitis limited to skin, not elsewhere classified	0.179	0.821
L94 Other localised connective tissue disorders	0.179	0.821
L93 Lupus erythematosus	0.179	0.821
L92 Granulomatous disorders of skin and subcutaneous tissue	0.179	0.821
L90 Atrophic disorders of skin	0.179	0.821
L89 Decubitus ulcer	0.179	0.821
L87 Transepidermal elimination disorders	0.179	0.821
L85 Other epidermal thickening	0.179	0.821
L81 Other disorders of pigmentation	0.179	0.821
L88 Pyoderma gangrenosum	0.179	0.821
L86 Keratoderma in diseases classified elsewhere	0.179	0.821
L84 Corns and callosities	0.179	0.821
L83 Acanthosis nigricans	0.179	0.821
L80 Vitiligo	0.179	0.821
N92.0 Excessive and frequent menstruation with regular cycle	0.179	0.821
C68 Malignant neoplasm of other and unspecified urinary organs	0.178	0.821
C66 Malignant neoplasm of ureter	0.178	0.821
C65 Malignant neoplasm of renal pelvis	0.178	0.821
C64 Malignant neoplasm of kidney, except renal pelvis	0.178	0.821
M51 Other intervertebral disk disorders	0.178	0.821
N39.3 Stress incontinence	0.178	0.822
F07 Personality and behavioural disorders due to brain disease, damage and dysfunction	0.178	0.822
F06 Other mental disorders due to brain damage and dysfunction and to physical disease	0.178	0.822
F05 Delirium, not induced by alcohol and other psychoactive substances	0.178	0.822
F02 Dementia in other diseases classified elsewhere	0.178	0.822
F01 Vascular dementia	0.178	0.822
F00 Dementia in Alzheimer's disease	0.178	0.822
F09 Unspecified organic or symptomatic mental disorder	0.178	0.822
F04 Organic amnesic syndrome, not induced by alcohol and other psychoactive substances	0.178	0.822
F03 Unspecified dementia	0.178	0.822
F25 Schizoaffective disorders	0.178	0.822
F23 Acute and transient psychotic disorders	0.178	0.822
F22 Persistent delusional disorders	0.178	0.822
F20 Schizophrenia	0.178	0.822
F29 Unspecified nonorganic psychosis	0.178	0.822
F28 Other nonorganic psychotic disorders	0.178	0.822
F24 Induced delusional disorder	0.178	0.822
F21 Schizotypal disorder	0.178	0.822
F53 Mental and behavioural disorders associated with the puerperium, not elsewhere classified	0.178	0.822
F52 Sexual dysfunction, not caused by organic disorder or disease	0.178	0.822
F51 Nonorganic sleep disorders	0.178	0.822
F50 Eating disorders	0.178	0.822
F59 Unspecified behavioural syndromes associated with physiological disturbances and physical factors	0.178	0.822
F55 Abuse of non-dependence-producing substances	0.178	0.822
F54 Psychological and behavioural factors associated with disorders or diseases classified elsewhere	0.178	0.822
F68 Other disorders of adult personality and behaviour	0.178	0.822
F66 Psychological and behavioural disorders associated with sexual development and orientation	0.178	0.822
F65 Disorders of sexual preference	0.178	0.822
F64 Gender identity disorders	0.178	0.822
F63 Habit and impulse disorders	0.178	0.822
F62 Enduring personality changes, not attributable to brain damage and disease	0.178	0.822
F60 Specific personality disorders	0.178	0.822
F69 Unspecified disorder of adult personality and behaviour	0.178	0.822
F61 Mixed and other personality disorders	0.178	0.822
F79 Unspecified mental retardation	0.178	0.822
F78 Other mental retardation	0.178	0.822
F73 Profound mental retardation	0.178	0.822
F72 Severe mental retardation	0.178	0.822
F71 Moderate mental retardation	0.178	0.822
F70 Mild mental retardation	0.178	0.822
F84 Pervasive developmental disorders	0.178	0.822
F81 Specific developmental disorders of scholastic skills	0.178	0.822
F80 Specific developmental disorders of speech and language	0.178	0.822
F89 Unspecified disorder of psychological development	0.178	0.822
F88 Other disorders of psychological development	0.178	0.822
F83 Mixed specific developmental disorders	0.178	0.822
F82 Specific developmental disorder of motor function	0.178	0.822
F98 Other behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.178	0.822
F95 Tic disorders	0.178	0.822
F94 Disorders of social functioning with onset specific to childhood and adolescence	0.178	0.822
F93 Emotional disorders with onset specific to childhood	0.178	0.822
F92 Mixed disorders of conduct and emotions	0.178	0.822
F91 Conduct disorders	0.178	0.822
F90 Hyperkinetic disorders	0.178	0.822
F99 Mental disorder, not otherwise specified	0.178	0.822
M18.9 Arthrosis of first carpometacarpal joint, unspecified	0.178	0.822

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations