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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs498240
log Bayes Factor = 20.1257
Chromosome 6   position 31,892,592  (GRCh37) Explore rs498240 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.000 1.000
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
E10.9 Without complications
0.000 0.000 1.000
M06.9 Rheumatoid arthritis, unspecified
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.000 1.000
E10-E14 Diabetes mellitus
0.000 0.001 0.999
E03 Other hypothyroidism
0.000 0.001 0.999
E00-E07 Disorders of thyroid gland
0.000 0.001 0.999
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.002 0.998
E10.3 With ophthalmic complications
0.000 0.013 0.987
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.037 0.963
E10.1 With ketoacidosis
0.000 0.053 0.947
M06 Other rheumatoid arthritis
0.000 0.083 0.917
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.084 0.916
L40.9 Psoriasis, unspecified
0.000 0.085 0.915
L40 Psoriasis
0.000 0.087 0.913
E11 Non-insulin-dependent diabetes mellitus
0.000 0.087 0.913
L40.5 Arthropathic psoriasis
0.000 0.090 0.910
E65-E68 Obesity and other hyperalimentation
0.000 0.093 0.907
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.110 0.890
E11.3 With ophthalmic complications
0.000 0.113 0.887
E05.9 Thyrotoxicosis, unspecified
0.000 0.133 0.867
E06 Thyroiditis
0.000 0.136 0.864
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.143 0.857
E10.5 With peripheral circulatory complications
0.000 0.155 0.845
E10.4 With neurological complications
0.000 0.164 0.836
M06.0 Seronegative rheumatoid arthritis
0.000 0.167 0.833
E66 Obesity
0.000 0.178 0.822
E10.2 With renal complications
0.000 0.185 0.814
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.187 0.813
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.189 0.811
E66.8 Other obesity
0.000 0.192 0.808
L40.0 Psoriasis vulgaris
0.000 0.203 0.797
E06.3 Autoimmune thyroiditis
0.000 0.217 0.782
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.219 0.781
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.226 0.774
E11.5 With peripheral circulatory complications
0.000 0.243 0.757
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.247 0.753
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.000 0.273 0.727
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.283 0.717
E10.7 With multiple complications
0.000 0.283 0.717
E10.6 With other specified complications
0.000 0.283 0.717
E10.0 With coma
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.716
E03.5 Myxoedema coma
0.000 0.284 0.716
E03.4 Atrophy of thyroid (acquired)
0.000 0.284 0.716
E03.3 Postinfectious hypothyroidism
0.000 0.284 0.716
E03.1 Congenital hypothyroidism without goitre
0.000 0.284 0.716
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.284 0.716
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.284 0.716
E00 Congenital iodine-deficiency syndrome
0.000 0.284 0.716
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.284 0.716
E65 Localised adiposity
0.000 0.289 0.711
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.000 0.299 0.701
E13 Other specified diabetes mellitus
0.000 0.302 0.698
M06.4 Inflammatory polyarthropathy
0.000 0.308 0.691
E05.8 Other thyrotoxicosis
0.000 0.309 0.690
E05.5 Thyroid crisis or storm
0.000 0.309 0.690
E05.4 Thyrotoxicosis factitia
0.000 0.309 0.690
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.309 0.690
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.309 0.690
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.309 0.690
M06.3 Rheumatoid nodule
0.000 0.314 0.686
E11.2 With renal complications
0.000 0.315 0.685
E11.0 With coma
0.000 0.320 0.680
E10.8 With unspecified complications
0.000 0.321 0.679
M05-M14 Inflammatory polyarthropathies
0.001 0.324 0.675
E11.1 With ketoacidosis
0.000 0.326 0.674
E50-E64 Other nutritional deficiencies
0.000 0.326 0.674
E40-E46 Malnutrition
0.000 0.335 0.665
M06.8 Other specified rheumatoid arthritis
0.000 0.343 0.657
M06.2 Rheumatoid bursitis
0.000 0.343 0.657
M06.1 Adult-onset Still's disease
0.000 0.343 0.657
E14 Unspecified diabetes mellitus
0.000 0.344 0.656
L40.8 Other psoriasis
0.000 0.345 0.654
L40.4 Guttate psoriasis
0.000 0.345 0.654
L40.3 Pustulosis palmaris et plantaris
0.000 0.345 0.654
L40.2 Acrodermatitis continua
0.000 0.345 0.654
L40.1 Generalised pustular psoriasis
0.000 0.345 0.654
E11.7 With multiple complications
0.000 0.346 0.654
E67 Other hyperalimentation
0.000 0.350 0.650
E68 Sequelae of hyperalimentation
0.000 0.350 0.650
E11.6 With other specified complications
0.000 0.357 0.642
E20-E35 Disorders of other endocrine glands
0.000 0.362 0.638
M07 Psoriatic and enteropathic arthropathies
0.001 0.366 0.633
E06.5 Other chronic thyroiditis
0.000 0.380 0.619
E06.4 Drug-induced thyroiditis
0.000 0.380 0.619
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.380 0.619
E06.1 Subacute thyroiditis
0.000 0.380 0.619
E06.0 Acute thyroiditis
0.000 0.380 0.619
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.387 0.612
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.391 0.609
M07.3 Other psoriatic arthropathies
0.000 0.397 0.603
E11.8 With unspecified complications
0.000 0.402 0.598
M06.08 Seronegative rheumatoid arthritis (Other)
0.000 0.402 0.597
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)
0.000 0.402 0.597
M06.06 Seronegative rheumatoid arthritis (Lower leg)
0.000 0.402 0.597
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)
0.000 0.402 0.597
M06.04 Seronegative rheumatoid arthritis (Hand)
0.000 0.402 0.597
M06.03 Seronegative rheumatoid arthritis (Forearm)
0.000 0.402 0.597
M06.02 Seronegative rheumatoid arthritis (Upper arm)
0.000 0.402 0.597
M06.01 Seronegative rheumatoid arthritis (Shoulder region)
0.000 0.402 0.597
E27 Other disorders of adrenal gland
0.000 0.405 0.595
M05 Seropositive rheumatoid arthritis
0.001 0.410 0.590
E66.2 Extreme obesity with alveolar hypoventilation
0.000 0.411 0.589
E66.1 Drug-induced obesity
0.000 0.411 0.589
E06.9 Thyroiditis, unspecified
0.000 0.426 0.574
E03.8 Other specified hypothyroidism
0.000 0.427 0.572
L40-L45 Papulosquamous disorders
0.000 0.448 0.551
E27.1 Primary adrenocortical insufficiency
0.000 0.450 0.550
M07.39 Other psoriatic arthropathies (Site unspecified)
0.000 0.454 0.546
M07.30 Other psoriatic arthropathies (Multiple sites)
0.000 0.462 0.538
E14.3 With ophthalmic complications
0.000 0.468 0.532
E66.0 Obesity due to excess calories
0.000 0.468 0.532
M06.49 Inflammatory polyarthropathy (Site unspecified)
0.000 0.470 0.530
M05.9 Seropositive rheumatoid arthritis, unspecified
0.000 0.471 0.529
M06.34 Rheumatoid nodule (Hand)
0.000 0.479 0.521
E11.4 With neurological complications
0.000 0.482 0.518
E55 Vitamin D deficiency
0.000 0.485 0.514
E12.9 Without complications
0.000 0.486 0.514
E12.8 With unspecified complications
0.000 0.486 0.514
E12.7 With multiple complications
0.000 0.486 0.514
E12.6 With other specified complications
0.000 0.486 0.514
E12.5 With peripheral circulatory complications
0.000 0.486 0.514
E12.4 With neurological complications
0.000 0.486 0.514
E12.3 With ophthalmic complications
0.000 0.486 0.514
E12.2 With renal complications
0.000 0.486 0.514
E12.1 With ketoacidosis
0.000 0.486 0.514
E12.0 With coma
0.000 0.486 0.514
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.486 0.513
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.486 0.513
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.486 0.513
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.486 0.513
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.486 0.513
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.486 0.513
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.486 0.513
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.486 0.513
E07 Other disorders of thyroid
0.000 0.492 0.507
M14 Arthropathies in other diseases classified elsewhere
0.001 0.493 0.506
E13.8 With unspecified complications
0.000 0.499 0.501
E13.7 With multiple complications
0.000 0.499 0.501
E13.6 With other specified complications
0.000 0.499 0.501
E13.5 With peripheral circulatory complications
0.000 0.499 0.501
E13.4 With neurological complications
0.000 0.499 0.501
E13.3 With ophthalmic complications
0.000 0.499 0.501
E13.2 With renal complications
0.000 0.499 0.501
E13.1 With ketoacidosis
0.000 0.499 0.501
E13.0 With coma
0.000 0.499 0.501
M06.48 Inflammatory polyarthropathy (Other)
0.000 0.504 0.496
M06.47 Inflammatory polyarthropathy (Ankle and foot)
0.000 0.504 0.496
M06.46 Inflammatory polyarthropathy (Lower leg)
0.000 0.504 0.496
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)
0.000 0.504 0.496
M06.44 Inflammatory polyarthropathy (Hand)
0.000 0.504 0.496
M06.43 Inflammatory polyarthropathy (Forearm)
0.000 0.504 0.496
M06.42 Inflammatory polyarthropathy (Upper arm)
0.000 0.504 0.496
M06.41 Inflammatory polyarthropathy (Shoulder region)
0.000 0.504 0.496
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.000 0.504 0.496
M06.39 Rheumatoid nodule (Site unspecified)
0.000 0.508 0.492
M06.38 Rheumatoid nodule (Other)
0.000 0.508 0.492
M06.37 Rheumatoid nodule (Ankle and foot)
0.000 0.508 0.492
M06.36 Rheumatoid nodule (Lower leg)
0.000 0.508 0.492
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.000 0.508 0.492
M06.33 Rheumatoid nodule (Forearm)
0.000 0.508 0.492
M06.32 Rheumatoid nodule (Upper arm)
0.000 0.508 0.492
M06.31 Rheumatoid nodule (Shoulder region)
0.000 0.508 0.492
M06.30 Rheumatoid nodule (Multiple sites)
0.000 0.508 0.492
E04 Other non-toxic goitre
0.000 0.513 0.487
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.513 0.487
M12 Other specific arthropathies
0.001 0.515 0.484
M09 Juvenile arthritis in diseases classified elsewhere
0.001 0.515 0.484
M08 Juvenile arthritis
0.001 0.515 0.484
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.517 0.483
E63 Other nutritional deficiencies
0.000 0.517 0.483
E56 Other vitamin deficiencies
0.000 0.517 0.483
E51 Thiamine deficiency
0.000 0.517 0.483
E50 Vitamin A deficiency
0.000 0.517 0.483
E60 Dietary zinc deficiency
0.000 0.517 0.483
E59 Dietary selenium deficiency
0.000 0.517 0.483
E58 Dietary calcium deficiency
0.000 0.517 0.483
E54 Ascorbic acid deficiency
0.000 0.517 0.483
E52 Niacin deficiency [pellagra]
0.000 0.517 0.483
E13.9 Without complications
0.000 0.518 0.482
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.523 0.476
E45 Retarded development following protein-energy malnutrition
0.000 0.523 0.476
E43 Unspecified severe protein-energy malnutrition
0.000 0.523 0.476
E42 Marasmic kwashiorkor
0.000 0.523 0.476
E41 Nutritional marasmus
0.000 0.523 0.476
E40 Kwashiorkor
0.000 0.523 0.476
M06.19 Adult-onset Still's disease (Site unspecified)
0.000 0.529 0.471
M06.18 Adult-onset Still's disease (Other)
0.000 0.529 0.471
M06.17 Adult-onset Still's disease (Ankle and foot)
0.000 0.529 0.471
M06.16 Adult-onset Still's disease (Lower leg)
0.000 0.529 0.471
M06.15 Adult-onset Still's disease (Pelvic region and thigh)
0.000 0.529 0.471
M06.14 Adult-onset Still's disease (Hand)
0.000 0.529 0.471
M06.13 Adult-onset Still's disease (Forearm)
0.000 0.529 0.471
M06.12 Adult-onset Still's disease (Upper arm)
0.000 0.529 0.471
M06.11 Adult-onset Still's disease (Shoulder region)
0.000 0.529 0.471
M06.10 Adult-onset Still's disease (Multiple sites)
0.000 0.529 0.471
M06.29 Rheumatoid bursitis (Site unspecified)
0.000 0.529 0.471
M06.28 Rheumatoid bursitis (Other)
0.000 0.529 0.471
M06.27 Rheumatoid bursitis (Ankle and foot)
0.000 0.529 0.471
M06.26 Rheumatoid bursitis (Lower leg)
0.000 0.529 0.471
M06.25 Rheumatoid bursitis (Pelvic region and thigh)
0.000 0.529 0.471
M06.24 Rheumatoid bursitis (Hand)
0.000 0.529 0.471
M06.23 Rheumatoid bursitis (Forearm)
0.000 0.529 0.471
M06.22 Rheumatoid bursitis (Upper arm)
0.000 0.529 0.471
M06.21 Rheumatoid bursitis (Shoulder region)
0.000 0.529 0.471
M06.20 Rheumatoid bursitis (Multiple sites)
0.000 0.529 0.471
M06.89 Other specified rheumatoid arthritis (Site unspecified)
0.000 0.529 0.471
M06.88 Other specified rheumatoid arthritis (Other)
0.000 0.529 0.471
M06.87 Other specified rheumatoid arthritis (Ankle and foot)
0.000 0.529 0.471
M06.86 Other specified rheumatoid arthritis (Lower leg)
0.000 0.529 0.471
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)
0.000 0.529 0.471
M06.84 Other specified rheumatoid arthritis (Hand)
0.000 0.529 0.471
M06.83 Other specified rheumatoid arthritis (Forearm)
0.000 0.529 0.471
M06.82 Other specified rheumatoid arthritis (Upper arm)
0.000 0.529 0.471
M06.81 Other specified rheumatoid arthritis (Shoulder region)
0.000 0.529 0.471
M06.80 Other specified rheumatoid arthritis (Multiple sites)
0.000 0.529 0.471
L43 Lichen planus
0.000 0.529 0.471
E14.8 With unspecified complications
0.000 0.529 0.470
E14.7 With multiple complications
0.000 0.529 0.470
E14.6 With other specified complications
0.000 0.529 0.470
E14.5 With peripheral circulatory complications
0.000 0.529 0.470
E14.4 With neurological complications
0.000 0.529 0.470
E14.2 Withrenal complications
0.000 0.529 0.470
E14.1 With ketoacidosis
0.000 0.529 0.470
E14.0 With coma
0.000 0.529 0.470
E67.8 Other specified hyperalimentation
0.000 0.534 0.466
E67.3 Hypervitaminosis D
0.000 0.534 0.466
E67.2 Megavitamin-B6 syndrome
0.000 0.534 0.466
E67.1 Hypercarotenaemia
0.000 0.534 0.466
E67.0 Hypervitaminosis A
0.000 0.534 0.466
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.534 0.466
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.534 0.466
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.543 0.457
E32 Diseases of thymus
0.000 0.543 0.457
E31 Polyglandular dysfunction
0.000 0.543 0.457
E30 Disorders of puberty, not elsewhere classified
0.000 0.543 0.457
E25 Adrenogenital disorders
0.000 0.543 0.457
E20 Hypoparathyroidism
0.000 0.543 0.457
E53 Deficiency of other B group vitamins
0.000 0.543 0.457
E27.8 Other specified disorders of adrenal gland
0.000 0.543 0.457
M07.6 Other enteropathic arthropathies
0.001 0.546 0.454
M07.5 Arthropathy in ulcerative colitis
0.001 0.546 0.454
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.001 0.546 0.454
M07.2 Psoriatic spondylitis
0.001 0.546 0.454
M07.1 Arthritis mutilans
0.001 0.546 0.454
M07.0 Distal interphalangeal psoriatic arthropathy
0.001 0.546 0.454
E28 Ovarian dysfunction
0.000 0.560 0.440
M11 Other crystal arthropathies
0.001 0.561 0.438
E15 Nondiabetic hypoglycaemic coma
0.000 0.563 0.436
E27.2 Addisonian crisis
0.000 0.564 0.436
E24 Cushing's syndrome
0.000 0.566 0.434
M07.38 Other psoriatic arthropathies (Other)
0.000 0.567 0.433
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.000 0.567 0.433
M07.36 Other psoriatic arthropathies (Lower leg)
0.000 0.567 0.433
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)
0.000 0.567 0.433
M07.34 Other psoriatic arthropathies (Hand)
0.000 0.567 0.433
M07.33 Other psoriatic arthropathies (Forearm)
0.000 0.567 0.433
M07.32 Other psoriatic arthropathies (Upper arm)
0.000 0.567 0.433
M07.31 Other psoriatic arthropathies (Shoulder region)
0.000 0.567 0.433
E22 Hyperfunction of pituitary gland
0.000 0.569 0.431
E61 Deficiency of other nutrient elements
0.000 0.570 0.430
E27.5 Adrenomedullary hyperfunction
0.000 0.573 0.426
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.573 0.426
E27.0 Other adrenocortical overactivity
0.000 0.573 0.426
E46 Unspecified protein-energy malnutrition
0.000 0.574 0.425
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.575 0.425
M05.8 Other seropositive rheumatoid arthritis
0.001 0.577 0.423
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.001 0.577 0.423
M05.2 Rheumatoid vasculitis
0.001 0.577 0.423
M05.1 Rheumatoid lung disease
0.001 0.577 0.423
M05.0 Felty's syndrome
0.001 0.577 0.423
L43.9 Lichen planus, unspecified
0.000 0.586 0.414
E26 Hyperaldosteronism
0.000 0.600 0.400
E55.9 Vitamin D deficiency, unspecified
0.000 0.600 0.400
L44 Other papulosquamous disorders
0.000 0.604 0.395
L41 Parapsoriasis
0.000 0.604 0.395
L45 Papulosquamous disorders in diseases classified elsewhere
0.000 0.604 0.395
M10 Gout
0.001 0.606 0.393
M14.6 Neuropathic arthropathy
0.001 0.615 0.385
E04.2 Non-toxic multinodular goitre
0.000 0.619 0.381
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)
0.000 0.621 0.379
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.621 0.379
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)
0.000 0.621 0.379
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.621 0.379
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)
0.000 0.621 0.379
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)
0.000 0.621 0.379
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)
0.000 0.621 0.379
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.621 0.379
E23 Hypofunction and other disorders of pituitary gland
0.000 0.621 0.379
E29 Testicular dysfunction
0.000 0.624 0.376
E55.0 Rickets, active
0.000 0.631 0.369
E04.0 Non-toxic diffuse goitre
0.000 0.634 0.366
E07.1 Dyshormogenetic goitre
0.000 0.636 0.364
E07.0 Hypersecretion of calcitonin
0.000 0.636 0.364
L42 Pityriasis rosea
0.000 0.636 0.364
M14.8 Arthropathies in other specified diseases classified elsewhere
0.001 0.636 0.363
M14.5 Arthropathies in other endocrine, nutritional and metabolic disorders
0.001 0.636 0.363
M14.4 Arthropathy in amyloidosis
0.001 0.636 0.363
M14.3 Lipoid dermatoarthritis
0.001 0.636 0.363
M14.2 Diabetic arthropathy
0.001 0.636 0.363
M14.1 Crystal arthropathy in other metabolic disorders
0.001 0.636 0.363
M14.0 Gouty arthropathy due to enzyme defects and other inherited disorders
0.001 0.636 0.363
E27.9 Disorder of adrenal gland, unspecified
0.000 0.637 0.363
M13 Other arthritis
0.000 0.642 0.358
E07.8 Other specified disorders of thyroid
0.000 0.642 0.357
E04.8 Other specified non-toxic goitre
0.000 0.650 0.349
E21.3 Hyperparathyroidism, unspecified
0.000 0.651 0.349
M08.9 Juvenile arthritis, unspecified
0.001 0.652 0.347
M08.8 Other juvenile arthritis
0.001 0.652 0.347
M08.4 Pauciarticular juvenile arthritis
0.001 0.652 0.347
M08.3 Juvenile polyarthritis (seronegative)
0.001 0.652 0.347
M08.2 Juvenile arthritis with systemic onset
0.001 0.652 0.347
M08.1 Juvenile ankylosing spondylitis
0.001 0.652 0.347
M08.0 Juvenile rheumatoid arthritis
0.001 0.652 0.347
M09.8 Juvenile arthritis in other diseases classified elsewhere
0.001 0.652 0.347
M09.2 Juvenile arthritis in ulcerative colitis
0.001 0.652 0.347
M09.1 Juvenile arthritis in Crohn's disease [regional enteritis]
0.001 0.652 0.347
M09.0 Juvenile arthritis in psoriasis
0.001 0.652 0.347
M12.8 Other specific arthropathies, not elsewhere classified
0.001 0.652 0.347
M12.5 Traumatic arthropathy
0.001 0.652 0.347
M12.4 Intermittent hydrarthrosis
0.001 0.652 0.347
M12.3 Palindromic rheumatism
0.001 0.652 0.347
M12.2 Villonodular synovitis (pigmented)
0.001 0.652 0.347
M12.1 Kaschin-Beck disease
0.001 0.652 0.347
M12.0 Chronic postrheumatic arthropathy [Jaccoud]
0.001 0.652 0.347
E34 Other endocrine disorders
0.000 0.652 0.347
E50.9 Vitamin A deficiency, unspecified
0.000 0.653 0.347
E50.8 Other manifestations of vitamin A deficiency
0.000 0.653 0.347
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.653 0.347
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.653 0.347
E50.5 Vitamin A deficiency with night blindness
0.000 0.653 0.347
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.653 0.347
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.653 0.347
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.653 0.347
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.653 0.347
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.653 0.347
E51.9 Thiamine deficiency, unspecified
0.000 0.653 0.347
E51.8 Other manifestations of thiamine deficiency
0.000 0.653 0.347
E51.2 Wernicke's encephalopathy
0.000 0.653 0.347
E51.1 Beriberi
0.000 0.653 0.347
E56.9 Vitamin deficiency, unspecified
0.000 0.653 0.347
E56.8 Deficiency of other vitamins
0.000 0.653 0.347
E56.1 Deficiency of vitamin K
0.000 0.653 0.347
E56.0 Deficiency of vitamin E
0.000 0.653 0.347
E63.9 Nutritional deficiency, unspecified
0.000 0.653 0.347
E63.8 Other specified nutritional deficiencies
0.000 0.653 0.347
E63.1 Imbalance of constituents of food intake
0.000 0.653 0.347
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.653 0.347
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.653 0.347
E64.8 Sequelae of other nutritional deficiencies
0.000 0.653 0.347
E64.3 Sequelae of rickets
0.000 0.653 0.347
E64.2 Sequelae of vitamin C deficiency
0.000 0.653 0.347
E64.1 Sequelae of vitamin A deficiency
0.000 0.653 0.347
E64.0 Sequelae of protein-energy malnutrition
0.000 0.653 0.347
E44.1 Mild protein-energy malnutrition
0.000 0.658 0.342
E44.0 Moderate protein-energy malnutrition
0.000 0.658 0.342
L43.8 Other lichen planus
0.000 0.662 0.338
L43.3 Subacute (active) lichen planus
0.000 0.662 0.338
L43.2 Lichenoid drug reaction
0.000 0.662 0.338
L43.1 Bullous lichen planus
0.000 0.662 0.338
L43.0 Hypertrophic lichen planus
0.000 0.662 0.338
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.666 0.334
E21.4 Other specified disorders of parathyroid gland
0.000 0.666 0.334
E21.2 Other hyperparathyroidism
0.000 0.666 0.334
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.666 0.334
E16 Other disorders of pancreatic internal secretion
0.000 0.670 0.330
E20.9 Hypoparathyroidism, unspecified
0.000 0.672 0.328
E20.8 Other hypoparathyroidism
0.000 0.672 0.328
E20.1 Pseudohypoparathyroidism
0.000 0.672 0.328
E20.0 Idiopathic hypoparathyroidism
0.000 0.672 0.328
E25.9 Adrenogenital disorder, unspecified
0.000 0.672 0.328
E25.8 Other adrenogenital disorders
0.000 0.672 0.328
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.672 0.328
E30.9 Disorder of puberty, unspecified
0.000 0.672 0.328
E30.8 Other disorders of puberty
0.000 0.672 0.328
E30.1 Precocious puberty
0.000 0.672 0.328
E30.0 Delayed puberty
0.000 0.672 0.328
E31.9 Polyglandular dysfunction, unspecified
0.000 0.672 0.328
E31.8 Other polyglandular dysfunction
0.000 0.672 0.328
E31.1 Polyglandular hyperfunction
0.000 0.672 0.328
E31.0 Autoimmune polyglandular failure
0.000 0.672 0.328
E32.9 Disease of thymus, unspecified
0.000 0.672 0.328
E32.8 Other diseases of thymus
0.000 0.672 0.328
E32.1 Abscess of thymus
0.000 0.672 0.328
E32.0 Persistent hyperplasia of thymus
0.000 0.672 0.328
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.672 0.328
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.672 0.328
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.672 0.328
E53.9 Vitamin B deficiency, unspecified
0.000 0.672 0.328
E53.1 Pyridoxine deficiency
0.000 0.672 0.328
E53.0 Riboflavin deficiency
0.000 0.672 0.328
E21.0 Primary hyperparathyroidism
0.000 0.673 0.327
M07.09 Distal interphalangeal psoriatic arthropathy (Site unspecified)
0.001 0.674 0.326
M07.08 Distal interphalangeal proriatic arthropathy-Other
0.001 0.674 0.326
M07.07 Distal interphalangeal psoriatic arthropathy (Ankle and foot)
0.001 0.674 0.326
M07.06 Distal interphalangeal proriatic arthropathy-Lower leg
0.001 0.674 0.326
M07.05 Distal interphalangeal proriatic arthropathy-Pelvic/thigh
0.001 0.674 0.326
M07.04 Distal interphalangeal psoriatic arthropathy (Hand)
0.001 0.674 0.326
M07.03 Distal interphalangeal proriatic arthropathy-Forearm
0.001 0.674 0.326
M07.02 Distal interphalangeal proriatic arthropathy-Upper arm
0.001 0.674 0.326
M07.01 Distal interphalangeal proriatic arthropathy-Shldr region
0.001 0.674 0.326
M07.00 Distal interphalangeal psoriatic arthropathy (Multiple sites)
0.001 0.674 0.326
M07.19 Arthritis mutilans (Site unspecified)
0.001 0.674 0.326
M07.18 Arthritis mutilans (Other)
0.001 0.674 0.326
M07.17 Arthritis mutilans (Ankle and foot)
0.001 0.674 0.326
M07.16 Arthritis mutilans (Lower leg)
0.001 0.674 0.326
M07.15 Arthritis mutilans (Pelvic region and thigh)
0.001 0.674 0.326
M07.14 Arthritis mutilans (Hand)
0.001 0.674 0.326
M07.13 Arthritis mutilans (Forearm)
0.001 0.674 0.326
M07.12 Arthritis mutilans (Upper arm)
0.001 0.674 0.326
M07.11 Arthritis mutilans (Shoulder region)
0.001 0.674 0.326
M07.10 Arthritis mutilans (Multiple sites)
0.001 0.674 0.326
M07.29 Psoriatic spondylitis (Site unspecified)
0.001 0.674 0.326
M07.28 Psoriatic spondylitis (Other)
0.001 0.674 0.326
M07.27 Psoriatic spondylitis (Ankle and foot)
0.001 0.674 0.326
M07.26 Psoriatic spondylitis (Lower leg)
0.001 0.674 0.326
M07.25 Psoriatic spondylitis (Pelvic region and thigh)
0.001 0.674 0.326
M07.24 Psoriatic spondylitis (Hand)
0.001 0.674 0.326
M07.23 Psoriatic spondylitis (Forearm)
0.001 0.674 0.326
M07.22 Psoriatic spondylitis (Upper arm)
0.001 0.674 0.326
M07.21 Psoriatic spondylitis (Shoulder region)
0.001 0.674 0.326
M07.20 Psoriatic spondylitis (Multiple sites)
0.001 0.674 0.326
M07.49 Arthropathy in Crohn's disease [regional enteritis] (Site unspecified)
0.001 0.674 0.326
M07.48 Arthropathy in Crohn's disease [regional enteritis] (Other)
0.001 0.674 0.326
M07.47 Arthropathy in Crohn's disease [regional enteritis] (Ankle and foot)
0.001 0.674 0.326
M07.46 Arthropathy in Crohn's disease [regional enteritis] (Lower leg)
0.001 0.674 0.326
M07.45 Arthropathy in Crohn's disease [regional enteritis] (Pelvic region and thigh)
0.001 0.674 0.326
M07.44 Arthropathy in Crohn's disease [regional enteritis] (Hand)
0.001 0.674 0.326
M07.43 Arthropathy in Crohn's disease [regional enteritis] (Forearm)
0.001 0.674 0.326
M07.42 Arthropathy in Crohn's disease [regional enteritis] (Upper arm)
0.001 0.674 0.326
M07.41 Arthropathy in Crohn's disease [regional enteritis] (Shoulder region)
0.001 0.674 0.326
M07.40 Arthropathy in Crohn's disease [regional enteritis] (Multiple sites)
0.001 0.674 0.326
M07.59 Arthropathy in ulcerative colitis (Site unspecified)
0.001 0.674 0.326
M07.58 Arthropathy in ulcerative colitis (Other)
0.001 0.674 0.326
M07.57 Arthropathy in ulcerative colitis (Ankle and foot)
0.001 0.674 0.326
M07.56 Arthropathy in ulcerative colitis (Lower leg)
0.001 0.674 0.326
M07.55 Arthropathy in ulcerative colitis (Pelvic region and thigh)
0.001 0.674 0.326
M07.54 Arthropathy in ulcerative colitis (Hand)
0.001 0.674 0.326
M07.53 Arthropathy in ulcerative colitis (Forearm)
0.001 0.674 0.326
M07.52 Arthropathy in ulcerative colitis (Upper arm)
0.001 0.674 0.326
M07.51 Arthropathy in ulcerative colitis (Shoulder region)
0.001 0.674 0.326
M07.50 Arthropathy in ulcerative colitis (Multiple sites)
0.001 0.674 0.326
M07.69 Other enteropathic arthropathies (Site unspecified)
0.001 0.674 0.326
M07.68 Other enteropathic arthropathies (Other)
0.001 0.674 0.326
M07.67 Other enteropathic arthropathies (Ankle and foot)
0.001 0.674 0.326
M07.66 Other enteropathic arthropathies (Lower leg)
0.001 0.674 0.326
M07.65 Other enteropathic arthropathies (Pelvic region and thigh)
0.001 0.674 0.326
M07.64 Other enteropathic arthropathies (Hand)
0.001 0.674 0.326
M07.63 Other enteropathic arthropathies (Forearm)
0.001 0.674 0.326
M07.62 Other enteropathic arthropathies (Upper arm)
0.001 0.674 0.326
M07.61 Other enteropathic arthropathies (Shoulder region)
0.001 0.674 0.326
M07.60 Other enteropathic arthropathies (Multiple sites)
0.001 0.674 0.326
E22.0 Acromegaly and pituitary gigantism
0.000 0.677 0.323
E28.9 Ovarian dysfunction, unspecified
0.000 0.684 0.316
E28.8 Other ovarian dysfunction
0.000 0.684 0.316
E28.3 Primary ovarian failure
0.000 0.684 0.316
E28.1 Androgen excess
0.000 0.684 0.316
E28.0 Oestrogen excess
0.000 0.684 0.316
M11.9 Crystal arthropathy, unspecified
0.001 0.685 0.314
M11.8 Other specified crystal arthropathies
0.001 0.685 0.314
M11.1 Familial chondrocalcinosis
0.001 0.685 0.314
M11.0 Hydroxyapatite deposition disease
0.001 0.685 0.314
E24.8 Other Cushing's syndrome
0.000 0.688 0.311
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.688 0.311
E24.3 Ectopic ACTH syndrome
0.000 0.688 0.311
E24.2 Drug-induced Cushing's syndrome
0.000 0.688 0.311
E24.1 Nelson's syndrome
0.000 0.688 0.311
E24.0 Pituitary-dependent Cushing's disease
0.000 0.688 0.311
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.691 0.309
E22.8 Other hyperfunction of pituitary gland
0.000 0.691 0.309
E22.1 Hyperprolactinaemia
0.000 0.691 0.309
E61.9 Deficiency of nutrient element, unspecified
0.000 0.692 0.308
E61.8 Deficiency of other specified nutrient elements
0.000 0.692 0.308
E61.7 Deficiency of multiple nutrient elements
0.000 0.692 0.308
E61.6 Vanadium deficiency
0.000 0.692 0.308
E61.5 Molybdenum deficiency
0.000 0.692 0.308
E61.4 Chromium deficiency
0.000 0.692 0.308
E61.3 Manganese deficiency
0.000 0.692 0.308
E61.2 Magnesium deficiency
0.000 0.692 0.308
E61.0 Copper deficiency
0.000 0.692 0.308
M05.09 Felty's syndrome (Site unspecified)
0.001 0.696 0.303
M05.08 Felty's syndrome (Other)
0.001 0.696 0.303
M05.07 Felty's syndrome (Ankle and foot)
0.001 0.696 0.303
M05.06 Felty's syndrome (Lower leg)
0.001 0.696 0.303
M05.05 Felty's syndrome (Pelvic region and thigh)
0.001 0.696 0.303
M05.04 Felty's syndrome (Hand)
0.001 0.696 0.303
M05.03 Felty's syndrome (Forearm)
0.001 0.696 0.303
M05.02 Felty's syndrome (Upper arm)
0.001 0.696 0.303
M05.01 Felty's syndrome (Shoulder region)
0.001 0.696 0.303
M05.00 Felty's syndrome (Multiple sites)
0.001 0.696 0.303
M05.19 Rheumatoid lung disease (Site unspecified)
0.001 0.696 0.303
M05.18 Rheumatoid lung disease (Other)
0.001 0.696 0.303
M05.17 Rheumatoid lung disease (Ankle and foot)
0.001 0.696 0.303
M05.16 Rheumatoid lung disease (Lower leg)
0.001 0.696 0.303
M05.15 Rheumatoid lung disease (Pelvic region and thigh)
0.001 0.696 0.303
M05.14 Rheumatoid lung disease (Hand)
0.001 0.696 0.303
M05.13 Rheumatoid lung disease (Forearm)
0.001 0.696 0.303

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

This website was created, designed, and edited by ORCID iD iconPatrick K. Albers

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