TreeWAS – Variant ID: rs4988235

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
G40 Epilepsy	0.299	0.701	0.000
G40-G47 Episodic and paroxysmal disorders	0.296	0.704	0.000
G40.9 Epilepsy, unspecified	0.289	0.711	0.000
G45 Transient cerebral ischaemic attacks and related syndromes	0.284	0.716	0.000
G44 Other headache syndromes	0.277	0.723	0.000
G45.4 Transient global amnesia	0.274	0.726	0.000
G40.5 Special epileptic syndromes	0.271	0.729	0.000
G40.6 Grand mal seizures, unspecified (with or without petit mal)	0.264	0.736	0.000
G40.7 Petit mal, unspecified, without grand mal seizures	0.259	0.741	0.000
G41 Status epilepticus	0.255	0.745	0.000
G44.0 Cluster headache syndrome	0.254	0.746	0.000
G40.8 Other epilepsy	0.246	0.754	0.000
G43 Migraine	0.239	0.761	0.000
G45.3 Amaurosis fugax	0.233	0.767	0.000
G44.3 Chronic posttraumatic headache	0.226	0.774	0.000
G41.9 Status epilepticus, unspecified	0.224	0.776	0.000
G40.3 Generalised idiopathic epilepsy and epileptic syndromes	0.223	0.777	0.000
G40.4 Other generalised epilepsy and epileptic syndromes	0.221	0.779	0.000
G44.4 Drug-induced headache, not elsewhere classified	0.218	0.782	0.000
G45.1 Carotid artery syndrome (hemispheric)	0.218	0.782	0.000
G43.1 Migraine with aura [classical migraine]	0.217	0.783	0.000
G44.8 Other specified headache syndromes	0.216	0.784	0.000
G46 Vascular syndromes of brain in cerebrovascular diseases	0.214	0.786	0.000
G44.1 Vascular headache, not elsewhere classified	0.211	0.789	0.000
G45.8 Other transient cerebral ischaemic attacks and related syndromes	0.209	0.791	0.000
G45.2 Multiple and bilateral precerebral artery syndromes	0.204	0.796	0.000
G45.9 Transient cerebral ischaemic attack, unspecified	0.201	0.799	0.000
G43.0 Migraine without aura [common migraine]	0.198	0.802	0.000
G41.2 Complex partial status epilepticus	0.197	0.803	0.000
G40.1 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures	0.194	0.806	0.000
G40.0 Localisation-related (focal) (partial) idiopathic epilepsy and epileptic syndromes with seizures of localised onset	0.191	0.809	0.000
G47 Sleep disorders	0.188	0.812	0.000
G41.0 Grand mal status epilepticus	0.187	0.813	0.000
G41.1 Petit mal status epilepticus	0.183	0.817	0.000
G43.2 Status migrainosus	0.177	0.823	0.000
G43.8 Other migraine	0.170	0.830	0.000
G46.7 Other lacunar syndromes	0.168	0.832	0.000
G47.9 Sleep disorder, unspecified	0.167	0.833	0.000
G41.8 Other status epilepticus	0.162	0.838	0.000
G45.0 Vertebro-basilar artery syndrome	0.160	0.840	0.000
G43.3 Complicated migraine	0.159	0.841	0.000
G46.4 Cerebellar stroke syndrome	0.155	0.844	0.000
G46.8 Other vascular syndromes of brain in cerebrovascular diseases	0.154	0.846	0.000
G46.6 Pure sensory lacunar syndrome	0.154	0.846	0.000
G46.5 Pure motor lacunar syndrome	0.154	0.846	0.000
G46.1 Anterior cerebral artery syndrome	0.154	0.846	0.000
G46.0 Middle cerebral artery syndrome	0.154	0.846	0.000
G46.2 Posterior cerebral artery syndrome	0.148	0.852	0.000
G47.3 Sleep apnoea	0.148	0.852	0.000
G46.3 Brain stem stroke syndrome	0.142	0.858	0.000
G47.8 Other sleep disorders	0.135	0.865	0.000
G44.2 Tension-type headache	0.128	0.872	0.000
G47.4 Narcolepsy and cataplexy	0.127	0.873	0.000
G47.1 Disorders of excessive somnolence [hypersomnias]	0.125	0.875	0.000
G47.2 Disorders of the sleep-wake schedule	0.124	0.875	0.000
G40.2 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures	0.107	0.892	0.000
G81.9 Hemiplegia, unspecified	0.066	0.934	0.000
G81 Hemiplegia	0.066	0.934	0.000
G80-G83 Cerebral palsy and other paralytic syndromes	0.066	0.934	0.000
Chapter VI Diseases of the nervous system	0.064	0.936	0.000
G82 Paraplegia and tetraplegia	0.061	0.939	0.000
G82.2 Paraplegia, unspecified	0.057	0.943	0.000
G30-G32 Other degenerative diseases of the nervous system	0.055	0.945	0.000
G30 Alzheimer's disease	0.053	0.947	0.000
G30.9 Alzheimer's disease, unspecified	0.053	0.947	0.000
G81.1 Spastic hemiplegia	0.053	0.947	0.000
G43.9 Migraine, unspecified	0.052	0.948	0.000
Z98.8 Other specified postsurgical states	0.049	0.951	0.000
G00-G09 Inflammatory diseases of the central nervous system	0.048	0.952	0.000
G81.0 Flaccid hemiplegia	0.048	0.952	0.000
G82.4 Spastic tetraplegia	0.046	0.954	0.000
G80 Infantile cerebral palsy	0.046	0.954	0.000
G20-G26 Extrapyramidal and movement disorders	0.044	0.956	0.000
G82.3 Flaccid tetraplegia	0.044	0.956	0.000
G82.0 Flaccid paraplegia	0.044	0.956	0.000
G82.5 Tetraplegia, unspecified	0.044	0.956	0.000
G83 Other paralytic syndromes	0.043	0.957	0.000
G30.8 Other Alzheimer's disease	0.041	0.959	0.000
G82.1 Spastic paraplegia	0.041	0.959	0.000
G30.1 Alzheimer's disease with late onset	0.040	0.959	0.000
G47.0 Disorders of initiating and maintaining sleep [insomnias]	0.039	0.960	0.001
G05 Encephalitis, myelitis and encephalomyelitis in diseases classified elsewhere	0.039	0.961	0.000
G02 Meningitis in other infectious and parasitic diseases classified elsewhere	0.038	0.962	0.000
G04 Encephalitis, myelitis and encephalomyelitis	0.038	0.962	0.000
G25 Other extrapyramidal and movement disorders	0.038	0.962	0.000
G83.8 Other specified paralytic syndromes	0.037	0.963	0.000
G80.8 Other infantile cerebral palsy	0.037	0.963	0.000
G32 Other degenerative disorders of nervous system in diseases classified elsewhere	0.037	0.963	0.000
G25.0 Essential tremor	0.035	0.965	0.000
G21 Secondary Parkinsonism	0.035	0.965	0.000
G00 Bacterial meningitis, not elsewhere classified	0.035	0.965	0.000
G07 Intracranial and intraspinal abscess and granuloma in diseases classified elsewhere	0.034	0.965	0.000
G04.8 Other encephalitis, myelitis and encephalomyelitis	0.034	0.966	0.000
G25.8 Other specified extrapyramidal and movement disorders	0.034	0.966	0.000
G80.9 Infantile cerebral palsy, unspecified	0.034	0.966	0.000
G83.3 Monoplegia, unspecified	0.034	0.966	0.000
G06 Intracranial and intraspinal abscess and granuloma	0.033	0.966	0.000
G03 Meningitis due to other and unspecified causes	0.033	0.967	0.000
G80.4 Ataxic cerebral palsy	0.033	0.967	0.000
G80.3 Dyskinetic cerebral palsy	0.033	0.967	0.000
G90-G99 Other disorders of the nervous system	0.033	0.967	0.000
G09 Sequelae of inflammatory diseases of central nervous system	0.033	0.967	0.000
G26 Extrapyramidal and movement disorders in diseases classified elsewhere	0.032	0.968	0.000
G22 Parkinsonism in diseases classified elsewhere	0.032	0.968	0.000
G80.2 Infantile hemiplegia	0.032	0.968	0.000
G02.0 Meningitis in viral diseases classified elsewhere	0.031	0.969	0.000
G05.0 Encephalitis, myelitis and encephalomyelitis in bacterial diseases classified elsewhere	0.031	0.969	0.000
G83.5 Locked-in syndrome	0.031	0.969	0.000
G83.0 Diplegia of upper limbs	0.031	0.969	0.000
G05.1 Encephalitis, myelitis and encephalomyelitis in viral diseases classified elsewhere	0.031	0.969	0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified	0.031	0.969	0.000
G83.1 Monoplegia of lower limb	0.031	0.969	0.000
G70-G73 Diseases of myoneural junction and muscle	0.031	0.969	0.000
G08 Intracranial and intraspinal phlebitis and thrombophlebitis	0.031	0.969	0.000
G00.1 Pneumococcal meningitis	0.030	0.970	0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.030	0.970	0.000
G25.1 Drug-induced tremor	0.030	0.970	0.000
G23 Other degenerative diseases of basal ganglia	0.030	0.970	0.000
G80.1 Spastic diplegia	0.030	0.970	0.000
G04.2 Bacterial meningoencephalitis and meningomyelitis, not elsewhere classified	0.029	0.970	0.000
G97.1 Other reaction to spinal and lumbar puncture	0.029	0.971	0.000
G05.8 Encephalitis, myelitis and encephalomyelitis in other diseases classified elsewhere	0.028	0.971	0.000
G05.2 Encephalitis, myelitis and encephalomyelitis in other infectious and parasitic diseases classified elsewhere	0.028	0.971	0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified	0.028	0.972	0.000
G80.0 Spastic cerebral palsy	0.028	0.972	0.000
G06.1 Intraspinal abscess and granuloma	0.028	0.972	0.000
G01 Meningitis in bacterial diseases classified elsewhere	0.028	0.972	0.000
G83.9 Paralytic syndrome, unspecified	0.028	0.972	0.000
G35-G37 Demyelinating diseases of the central nervous system	0.028	0.972	0.000
G02.8 Meningitis in other specified infectious and parasitic diseases classified elsewhere	0.028	0.972	0.000
G02.1 Meningitis in mycoses	0.028	0.972	0.000
G04.1 Tropical spastic paraplegia	0.028	0.972	0.000
G21.0 Malignant neuroleptic syndrome	0.027	0.972	0.000
G97.8 Other postprocedural disorders of nervous system	0.028	0.972	0.000
G25.6 Drug-induced tics and other tics of organic origin	0.027	0.973	0.000
G25.4 Drug-induced chorea	0.027	0.973	0.000
G21.4 Vascular parkinsonism	0.027	0.973	0.000
G96 Other disorders of central nervous system	0.027	0.973	0.000
G21.9 Secondary Parkinsonism, unspecified	0.027	0.973	0.000
G32.0 Subacute combined degeneration of spinal cord in diseases classified elsewhere	0.026	0.973	0.000
G83.2 Monoplegia of upper limb	0.026	0.974	0.000
G94 Other disorders of brain in diseases classified elsewhere	0.026	0.974	0.000
G21.8 Other secondary Parkinsonism	0.025	0.974	0.000
G21.3 Postencephalitic Parkinsonism	0.025	0.974	0.000
G21.2 Secondary Parkinsonism due to other external agents	0.025	0.974	0.000
G04.0 Acute disseminated encephalitis	0.025	0.975	0.000
G00.0 Haemophilus meningitis	0.025	0.975	0.000
G00.8 Other bacterial meningitis	0.025	0.975	0.000
G03.0 Nonpyogenic meningitis	0.025	0.975	0.000
G24 Dystonia	0.024	0.976	0.000
G25.2 Other specified forms of tremor	0.024	0.976	0.000
G03.8 Meningitis due to other specified causes	0.024	0.976	0.000
G03.2 Benign recurrent meningitis [Mollaret]	0.024	0.976	0.000
G03.1 Chronic meningitis	0.024	0.976	0.000
G00.2 Streptococcal meningitis	0.024	0.976	0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.024	0.976	0.000
G20 Parkinson's disease	0.024	0.976	0.000
G92 Toxic encephalopathy	0.024	0.976	0.000
G00.3 Staphylococcal meningitis	0.024	0.976	0.000
G30.0 Alzheimer's disease with early onset	0.023	0.976	0.000
G32.8 Other specified degenerative disorders of nervous system in diseases classified elsewhere	0.023	0.977	0.000
G21.1 Other drug-induced secondary Parkinsonism	0.023	0.977	0.000
G96.1 Disorders of meninges, not elsewhere classified	0.023	0.977	0.000
G36 Other acute disseminated demyelination	0.023	0.977	0.000
G96.0 Cerebrospinal fluid leak	0.023	0.977	0.000
G98 Other disorders of nervous system, not elsewhere classified	0.023	0.977	0.000
G83.4 Cauda equina syndrome	0.023	0.977	0.000
G97.9 Postprocedural disorder of nervous system, unspecified	0.022	0.977	0.000
G97.2 Intracranial hypotension following ventricular shunting	0.022	0.977	0.000
G23.8 Other specified degenerative diseases of basal ganglia	0.022	0.978	0.000
G94.1 Hydrocephalus in neoplastic disease	0.022	0.978	0.000
G25.5 Other chorea	0.022	0.978	0.000
G03.9 Meningitis, unspecified	0.022	0.978	0.000
G23.9 Degenerative disease of basal ganglia, unspecified	0.022	0.978	0.000
G23.3 Multiple system atrophy, cerebellar type	0.022	0.978	0.000
G23.2 Striatonigral degeneration	0.022	0.978	0.000
G23.0 Hallervorden-Spatz disease	0.022	0.978	0.000
G11 Hereditary ataxia	0.021	0.979	0.000
G73 Disorders of myoneural junction and muscle in diseases classified elsewhere	0.021	0.979	0.000
G12 Spinal muscular atrophy and related syndromes	0.021	0.979	0.000
G25.3 Myoclonus	0.021	0.979	0.000
G91 Hydrocephalus	0.021	0.979	0.000
G31.8 Other specified degenerative diseases of nervous system	0.021	0.979	0.000
G06.2 Extradural and subdural abscess, unspecified	0.021	0.979	0.000
G31.9 Degenerative disease of nervous system, unspecified	0.021	0.979	0.000
G06.0 Intracranial abscess and granuloma	0.020	0.979	0.000
G31.1 Senile degeneration of brain, not elsewhere classified	0.020	0.979	0.000
G72 Other myopathies	0.020	0.980	0.000
G04.9 Encephalitis, myelitis and encephalomyelitis, unspecified	0.020	0.980	0.000
G13 Systemic atrophies primarily affecting central nervous system in diseases classified elsewhere	0.020	0.980	0.000
G91.1 Obstructive hydrocephalus	0.020	0.980	0.000
G71 Primary disorders of muscles	0.020	0.980	0.000
G90 Disorders of autonomic nervous system	0.020	0.980	0.000
G25.9 Extrapyramidal and movement disorder, unspecified	0.019	0.981	0.000
G36.0 Neuromyelitis optica [Devic]	0.019	0.981	0.000
G23.1 Progressive supranuclear ophthalmoplegia [Steele-Richardson-Olszewski]	0.019	0.981	0.000
G10 Huntington's disease	0.019	0.981	0.000
G97.0 Cerebrospinal fluid leak from spinal puncture	0.019	0.981	0.000
G00.9 Bacterial meningitis, unspecified	0.019	0.981	0.000
G94.8 Other specified disorders of brain in diseases classified elsewhere	0.018	0.981	0.000
G94.0 Hydrocephalus in infectious and parasitic diseases classified elsewhere	0.018	0.981	0.000
G24.3 Spasmodic torticollis	0.018	0.981	0.000
G96.9 Disorder of central nervous system, unspecified	0.018	0.981	0.000
G31.0 Circumscribed brain atrophy	0.018	0.981	0.000
G24.5 Blepharospasm	0.018	0.982	0.000
G24.8 Other dystonia	0.018	0.982	0.000
G24.1 Idiopathic familial dystonia	0.018	0.982	0.000
G24.4 Idiopathic orofacial dystonia	0.018	0.982	0.000
G24.2 Idiopathic nonfamilial dystonia	0.018	0.982	0.000
G62 Other polyneuropathies	0.017	0.983	0.000
G70 Myasthenia gravis and other myoneural disorders	0.017	0.983	0.000
G14 Postpolio syndrome	0.017	0.983	0.000
G24.0 Drug-induced dystonia	0.017	0.983	0.000
G96.8 Other specified disorders of central nervous system	0.017	0.983	0.000
G90.0 Idiopathic peripheral autonomic neuropathy	0.017	0.983	0.000
G36.9 Acute disseminated demyelination, unspecified	0.017	0.983	0.000
G36.8 Other specified acute disseminated demyelination	0.017	0.983	0.000
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]	0.017	0.983	0.000
G60 Hereditary and idiopathic neuropathy	0.016	0.983	0.000
G11.9 Hereditary ataxia, unspecified	0.016	0.984	0.000
G73.7 Myopathy other diseases classified elsewhere	0.016	0.984	0.000
G37 Other demyelinating diseases of central nervous system	0.016	0.984	0.000
G94.2 Hydrocephalus in other diseases classified elsewhere	0.016	0.984	0.000
G64 Other disorders of peripheral nervous system	0.016	0.984	0.000
G91.3 Posttraumatic hydrocephalus, unspecified	0.015	0.984	0.000
G11.8 Other hereditary ataxias	0.015	0.984	0.000
G11.3 Cerebellar ataxia with defective DNA repair	0.015	0.984	0.000
G11.2 Late-onset cerebellar ataxia	0.015	0.984	0.000
G11.0 Congenital nonprogressive ataxia	0.015	0.984	0.000
G93 Other disorders of brain	0.016	0.984	0.000
G72.9 Myopathy, unspecified	0.015	0.984	0.000
G12.9 Spinal muscular atrophy, unspecified	0.015	0.984	0.000
G12.8 Other spinal muscular atrophies and related syndromes	0.015	0.984	0.000
G12.1 Other inherited spinal muscular atrophy	0.015	0.984	0.000
G12.0 Infantile spinal muscular atrophy, type I [Werdnig-Hoffman]	0.015	0.984	0.000
G73.6 Myopathy in metabolic diseases	0.015	0.984	0.000
G73.5 Myopathy in endocrine diseases	0.015	0.984	0.000
G73.4 Myopathy in infectious and parasitic diseases classified elsewhere	0.015	0.984	0.000
G73.3 Myasthenic syndromes in other diseases classified elsewhere	0.015	0.984	0.000
G73.2 Other myasthenic syndromes in neoplastic disease	0.015	0.984	0.000
G73.1 Eaton-Lambert syndrome	0.015	0.984	0.000
G72.0 Drug-induced myopathy	0.015	0.985	0.000
G11.1 Early-onset cerebellar ataxia	0.015	0.985	0.000
G91.2 Normal-pressure hydrocephalus	0.015	0.985	0.000
G90.8 Other disorders of autonomic nervous system	0.015	0.985	0.000
G62.0 Drug-induced polyneuropathy	0.015	0.985	0.000
G71.3 Mitochondrial myopathy, not elsewhere classified	0.015	0.985	0.000
G72.1 Alcoholic myopathy	0.015	0.985	0.000
G91.8 Other hydrocephalus	0.015	0.985	0.000
G72.3 Periodic paralysis	0.015	0.985	0.000
G72.2 Myopathy due to other toxic agents	0.015	0.985	0.000
G12.2 Motor neuron disease	0.015	0.985	0.000
G13.8 Systemic atrophy primarily affecting central nervous system in other diseases classified elsewhere	0.014	0.985	0.000
G13.2 Systemic atrophy primarily affecting central nervous system in myxoedema	0.014	0.985	0.000
G13.1 Other systemic atrophy primarily affecting central nervous system in neoplastic disease	0.014	0.985	0.000
K11.5 Sialolithiasis	0.015	0.985	0.000
G11.4 Hereditary spastic paraplegia	0.014	0.985	0.000
G72.4 Inflammatory myopathy, not elsewhere classified	0.014	0.985	0.000
G71.9 Primary disorder of muscle, unspecified	0.014	0.985	0.000
G71.8 Other primary disorders of muscles	0.014	0.985	0.000
G71.2 Congenital myopathies	0.014	0.985	0.000
R26.8 Other and unspecified abnormalities of gait and mobility	0.014	0.986	0.000
G63 Polyneuropathy in diseases classified elsewhere	0.014	0.986	0.000
G90.4 Autonomic dysreflexia	0.014	0.986	0.000
G90.1 Familial dysautonomia [Riley-Day]	0.014	0.986	0.000
G60.0 Hereditary motor and sensory neuropathy	0.014	0.986	0.000
G93.5 Compression of brain	0.014	0.986	0.000
G73.0 Myasthenic syndromes in endocrine diseases	0.013	0.986	0.000
G71.1 Myotonic disorders	0.014	0.986	0.000
G93.6 Cerebral oedema	0.013	0.986	0.000
G93.2 Benign intracranial hypertension	0.013	0.987	0.000
G90.2 Horner's syndrome	0.013	0.987	0.000
G13.0 Paraneoplastic neuromyopathy and neuropathy	0.012	0.987	0.000
G62.2 Polyneuropathy due to other toxic agents	0.013	0.987	0.000
G70.8 Other specified myoneural disorders	0.012	0.987	0.000
G70.2 Congenital and developmental myasthenia	0.012	0.987	0.000
G70.1 Toxic myoneural disorders	0.012	0.987	0.000
G99 Other disorders of nervous system in diseases classified elsewhere	0.013	0.987	0.000
G71.0 Muscular dystrophy	0.012	0.987	0.000
G95 Other diseases of spinal cord	0.012	0.988	0.000
G62.8 Other specified polyneuropathies	0.012	0.988	0.000
G60.3 Idiopathic progressive neuropathy	0.012	0.988	0.000
G60.2 Neuropathy in association with hereditary ataxia	0.012	0.988	0.000
G60.1 Refsum's disease	0.012	0.988	0.000
G91.0 Communicating hydrocephalus	0.012	0.988	0.000
G37.5 Concentric sclerosis [Balo]	0.012	0.988	0.000
G37.4 Subacute necrotising myelitis	0.012	0.988	0.000
G37.2 Central pontine myelinolysis	0.012	0.988	0.000
G37.1 Central demyelination of corpus callosum	0.012	0.988	0.000
G37.0 Diffuse sclerosis	0.012	0.988	0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction	0.012	0.988	0.000
G90.3 Multisystem degeneration	0.011	0.988	0.000
G93.8 Other specified disorders of brain	0.012	0.988	0.000
G37.9 Demyelinating disease of central nervous system, unspecified	0.011	0.988	0.000
G93.7 Reye's syndrome	0.011	0.989	0.000
G70.0 Myasthenia gravis	0.011	0.989	0.000
G37.8 Other specified demyelinating diseases of central nervous system	0.011	0.989	0.000
G62.1 Alcoholic polyneuropathy	0.011	0.989	0.000
G72.8 Other specified myopathies	0.011	0.989	0.000
I69.3 Sequelae of cerebral infarction	0.011	0.989	0.000
I69 Sequelae of cerebrovascular disease	0.011	0.989	0.000
R45.1 Restlessness and agitation	0.011	0.989	0.000
G61 Inflammatory polyneuropathy	0.011	0.989	0.000
G63.8 Polyneuropathy in other diseases classified elsewhere	0.010	0.989	0.000
G63.6 Polyneuropathy in other musculoskeletal disorders	0.010	0.989	0.000
G63.5 Polyneuropathy in systemic connective tissue disorders	0.010	0.989	0.000
G63.4 Polyneuropathy in nutritional deficiency	0.010	0.989	0.000
G63.3 Polyneuropathy in other endocrine and metabolic diseases	0.010	0.989	0.000
G63.1 Polyneuropathy in neoplastic disease	0.010	0.989	0.000
G63.0 Polyneuropathy in infectious and parasitic diseases classified elsewhere	0.010	0.989	0.000
G62.9 Polyneuropathy, unspecified	0.011	0.989	0.000
G93.0 Cerebral cysts	0.011	0.989	0.000
I69.0 Sequelae of subarachnoid haemorrhage	0.010	0.990	0.000
G60.9 Hereditary and idiopathic neuropathy, unspecified	0.010	0.990	0.000
G31.2 Degeneration of nervous system due to alcohol	0.010	0.990	0.001
G60.8 Other hereditary and idiopathic neuropathies	0.010	0.990	0.000
G95.1 Vascular myelopathies	0.010	0.990	0.000
R26 Abnormalities of gait and mobility	0.010	0.990	0.000
G70.9 Myoneural disorder, unspecified	0.009	0.991	0.000
K11 Diseases of salivary glands	0.009	0.991	0.000
G90.9 Disorder of autonomic nervous system, unspecified	0.009	0.991	0.000
G99.8 Other specified disorders of nervous system in diseases classified elsewhere	0.009	0.991	0.000
G99.1 Other disorders of autonomic nervous system in other diseases classified elsewhere	0.009	0.991	0.000
G93.4 Encephalopathy, unspecified	0.009	0.991	0.000
K11.1 Hypertrophy of salivary gland	0.009	0.991	0.000
R26.3 Immobility	0.009	0.991	0.000
I69.2 Sequelae of other nontraumatic intracranial haemorrhage	0.009	0.991	0.000
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system	0.009	0.991	0.000
K11.9 Disease of salivary gland, unspecified	0.009	0.991	0.000
R26.0 Ataxic gait	0.008	0.992	0.000
G24.9 Dystonia, unspecified	0.008	0.992	0.000
K11.8 Other diseases of salivary glands	0.008	0.992	0.000
G95.0 Syringomyelia and syringobulbia	0.008	0.992	0.000
G61.1 Serum neuropathy	0.008	0.992	0.000
G95.2 Cord compression, unspecified	0.008	0.992	0.000
G61.9 Inflammatory polyneuropathy, unspecified	0.008	0.992	0.000
G63.2 Diabetic polyneuropathy	0.007	0.993	0.000
R45 Symptoms and signs involving emotional state	0.007	0.993	0.000
G93.9 Disorder of brain, unspecified	0.007	0.993	0.000
G99.0 Autonomic neuropathy in endocrine and metabolic diseases	0.007	0.993	0.000
G95.8 Other specified diseases of spinal cord	0.007	0.993	0.000
I69.1 Sequelae of intracerebral haemorrhage	0.007	0.993	0.000
R26.1 Paralytic gait	0.007	0.993	0.000
K11.0 Atrophy of salivary gland	0.007	0.993	0.000
K11.4 Fistula of salivary gland	0.007	0.993	0.000
K11.3 Abscess of salivary gland	0.007	0.993	0.000
G93.1 Anoxic brain damage, not elsewhere classified	0.007	0.993	0.000
K11.7 Disturbances of salivary secretion	0.007	0.993	0.000
G61.8 Other inflammatory polyneuropathies	0.006	0.993	0.000
I69.8 Sequelae of other and unspecified cerebrovascular diseases	0.006	0.994	0.000
M47.80 Other spondylosis (Multiple sites in spine)	0.006	0.994	0.000
M79.10 Myalgia (Multiple sites)	0.000	0.994	0.006
R45.8 Other symptoms and signs involving emotional state	0.006	0.994	0.000
R45.5 Hostility	0.006	0.994	0.000
R45.0 Nervousness	0.006	0.994	0.000
R45.6 Physical violence	0.006	0.994	0.000
L30.9 Dermatitis, unspecified	0.000	0.994	0.006
R45.7 State of emotional shock and stress, unspecified	0.006	0.994	0.000
G95.9 Disease of spinal cord, unspecified	0.006	0.994	0.000
R26.2 Difficulty in walking, not elsewhere classified	0.006	0.994	0.000
R45.2 Unhappiness	0.006	0.994	0.000
R45.3 Demoralisation and apathy	0.005	0.994	0.000
K11.6 Mucocele of salivary gland	0.005	0.995	0.000
M47.87 Other spondylosis (Lumbosacral region)	0.005	0.995	0.000
G91.9 Hydrocephalus, unspecified	0.005	0.995	0.000
R45.4 Irritability and anger	0.004	0.996	0.000
M21.37 Wrist or foot drop (acquired) (Ankle and foot)	0.000	0.996	0.004
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria	0.004	0.996	0.000
E73.9 Lactose intolerance, unspecified	0.000	0.996	0.004
G61.0 Guillain-Barre syndrome	0.004	0.996	0.000
K11.2 Sialoadenitis	0.004	0.996	0.000
O71.7 Obstetric haematoma of pelvis	0.000	0.996	0.004
K62.4 Stenosis of anus and rectum	0.004	0.996	0.000
O71.8 Other specified obstetric trauma	0.000	0.996	0.004
C71.9 Brain, unspecified	0.004	0.996	0.000
D58.9 Hereditary haemolytic anaemia, unspecified	0.000	0.997	0.003
D59.9 Acquired haemolytic anaemia, unspecified	0.000	0.997	0.003
O71 Other obstetric trauma	0.000	0.997	0.003
I49.8 Other specified cardiac arrhythmias	0.003	0.997	0.000
M47.8 Other spondylosis	0.003	0.997	0.000
N13.0 Hydronephrosis with ureteropelvic junction obstruction	0.000	0.997	0.003
M79.1 Myalgia	0.000	0.997	0.003
D89.2 Hypergammaglobulinaemia, unspecified	0.000	0.997	0.003
M79.16 Myalgia (Lower leg)	0.000	0.997	0.003
D59 Acquired haemolytic anaemia	0.000	0.997	0.003
C79.3 Secondary malignant neoplasm of brain and cerebral meninges	0.003	0.997	0.000
O71.3 Obstetric laceration of cervix	0.000	0.997	0.003
O71.9 Obstetric trauma, unspecified	0.000	0.997	0.003
D12.8 Rectum	0.000	0.997	0.003
L30 Other dermatitis	0.000	0.997	0.003
M79.15 Myalgia (Pelvic region and thigh)	0.000	0.997	0.003
G99.2 Myelopathy in diseases classified elsewhere	0.003	0.997	0.000
C78.5 Secondary malignant neoplasm of large intestine and rectum	0.000	0.997	0.003
D58 Other hereditary haemolytic anaemias	0.000	0.997	0.003
I07.1 Tricuspid insufficiency	0.003	0.997	0.000
D89.0 Polyclonal hypergammaglobulinaemia	0.000	0.997	0.003
M47.85 Other spondylosis (Thoracolumbar region)	0.003	0.997	0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.000	0.997	0.003
O71.6 Obstetric damage to pelvic joints and ligaments	0.000	0.997	0.003
O71.4 Obstetric high vaginal laceration alone	0.000	0.997	0.003
O71.5 Other obstetric injury to pelvic organs	0.000	0.997	0.003
O42.0 Premature rupture of membranes, onset of labour within 24 hours	0.000	0.997	0.003
O71.2 Postpartum inversion of uterus	0.000	0.997	0.003
O71.1 Rupture of uterus during labour	0.000	0.997	0.003
O71.0 Rupture of uterus before onset of labour	0.000	0.997	0.003
D89.9 Disorder involving the immune mechanism, unspecified	0.000	0.997	0.003
M47.81 Other spondylosis (Occipito-atlanto-axial region)	0.003	0.997	0.000
D59.0 Drug-induced autoimmune haemolytic anaemia	0.000	0.997	0.003
H57.9 Disorder of eye and adnexa, unspecified	0.000	0.997	0.003
M47.84 Other spondylosis (Thoracic region)	0.003	0.997	0.000
M79.17 Myalgia (Ankle and foot)	0.000	0.997	0.003
M79.14 Myalgia (Hand)	0.000	0.997	0.003
M79.13 Myalgia (Forearm)	0.000	0.997	0.003
M79.12 Myalgia (Upper arm)	0.000	0.997	0.003
D59.1 Other autoimmune haemolytic anaemias	0.000	0.997	0.003
D11.9 Major salivary gland, unspecified	0.003	0.997	0.000
C71 Malignant neoplasm of brain	0.003	0.997	0.000
M47.88 Other spondylosis (Sacral and sacrococcygeal region)	0.002	0.997	0.000
M47.83 Other spondylosis (Cervicothoracic region)	0.002	0.997	0.000
Z98 Other postsurgical states	0.003	0.997	0.000
M79.11 Myalgia (Shoulder region)	0.000	0.997	0.002
O14.1 Severe preeclampsia	0.002	0.997	0.000
D58.0 Hereditary spherocytosis	0.000	0.998	0.002
D59.8 Other acquired haemolytic anaemias	0.000	0.998	0.002
D59.6 Haemoglobinuria due to haemolysis from other external causes	0.000	0.998	0.002
D59.5 Paroxysmal nocturnal haemoglobinuria [Marchiafava-Micheli]	0.000	0.998	0.002
D59.3 Haemolytic-uraemic syndrome	0.000	0.998	0.002
D59.2 Drug-induced nonautoimmune haemolytic anaemia	0.000	0.998	0.002
M79.18 Myalgia (Other)	0.000	0.998	0.002
C71.2 Temporal lobe	0.002	0.998	0.000
C71.0 Cerebrum, except lobes and ventricles	0.002	0.998	0.000
D59.4 Other nonautoimmune haemolytic anaemias	0.000	0.998	0.002
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified	0.000	0.998	0.002
M21.3 Wrist or foot drop (acquired)	0.000	0.998	0.002
L30.8 Other specified dermatitis	0.000	0.998	0.002
O11 Pre-existing hypertensive disorder with superimposed proteinuria	0.002	0.998	0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.002	0.998	0.000
O42.9 Premature rupture of membranes, unspecified	0.000	0.998	0.002
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria	0.002	0.998	0.000
L30.5 Pityriasis alba	0.000	0.998	0.002
L30.2 Cutaneous autosensitisation	0.000	0.998	0.002
N64.4 Mastodynia	0.002	0.998	0.000
N61 Inflammatory disorders of breast	0.002	0.998	0.000
D55-D59 Haemolytic anaemias	0.000	0.998	0.002
C71.8 Overlapping lesion of brain	0.002	0.998	0.000
I31.3 Pericardial effusion (noninflammatory)	0.002	0.998	0.000
L20.9 Atopic dermatitis, unspecified	0.000	0.998	0.002
S40.0 Contusion of shoulder and upper arm	0.002	0.998	0.000
D58.8 Other specified hereditary haemolytic anaemias	0.000	0.998	0.002
D58.1 Hereditary elliptocytosis	0.000	0.998	0.002
D89.1 Cryoglobulinaemia	0.000	0.998	0.002
L30.4 Erythema intertrigo	0.000	0.998	0.002
M79.19 Myalgia (Site unspecified)	0.000	0.998	0.002
L30.0 Nummular dermatitis	0.000	0.998	0.002
N70.1 Chronic salpingitis and oophoritis	0.000	0.998	0.002
M21.33 Wrist or foot drop (acquired) (Forearm)	0.000	0.998	0.002
D63.0 Anaemia in neoplastic disease	0.002	0.998	0.000
D89.3 Immune reconstitution syndrome	0.000	0.998	0.002
H60.9 Otitis externa, unspecified	0.002	0.998	0.000
N60.4 Mammary duct ectasia	0.002	0.998	0.000
C71.5 Cerebral ventricle	0.002	0.998	0.000
L30.3 Infective dermatitis	0.000	0.998	0.002
L30.1 Dyshidrosis [pompholyx]	0.000	0.998	0.002
D58.2 Other haemoglobinopathies	0.000	0.998	0.002
M47.89 Other spondylosis (Site unspecified)	0.002	0.998	0.000
Z83.3 Family history of diabetes mellitus	0.000	0.998	0.002
C71.7 Brain stem	0.002	0.998	0.000
H60.8 Other otitis externa	0.002	0.998	0.000
O14.0 Moderate preeclampsia	0.002	0.998	0.000
M47.82 Other spondylosis (Cervical region)	0.002	0.998	0.000
C71.4 Occipital lobe	0.002	0.998	0.000
N64.5 Other signs and symptoms in breast	0.002	0.998	0.000
C71.6 Cerebellum	0.002	0.998	0.000
C71.3 Parietal lobe	0.002	0.998	0.000
M65.43 Radial styloid tenosynovitis [de Quervain] (Forearm)	0.002	0.998	0.000
M21.39 Wrist or foot drop (acquired)-Site unspec	0.000	0.998	0.002
M21.38 Wrist or foot drop (acquired)-Other	0.000	0.998	0.002
M21.36 Wrist or foot drop (acquired)-Lower leg	0.000	0.998	0.002
M21.35 Wrist or foot drop (acquired)-Pelvic/thigh	0.000	0.998	0.002
M21.34 Wrist or foot drop (acquired) (Hand)	0.000	0.998	0.002
M21.32 Wrist or foot drop (acquired)-Upper arm	0.000	0.998	0.002
M21.31 Wrist or foot drop (acquired)-Shldr region	0.000	0.998	0.002
M21.30 Wrist or foot drop (acquired) (Multiple sites)	0.000	0.998	0.002
E16.2 Hypoglycaemia, unspecified	0.000	0.998	0.002
O14.2 HELLP syndrome	0.002	0.998	0.000
N64 Other disorders of breast	0.002	0.998	0.000
O15 Eclampsia	0.002	0.998	0.000
D56 Thalassaemia	0.000	0.998	0.002
D55 Anaemia due to enzyme disorders	0.000	0.998	0.002
H60 Otitis externa	0.002	0.998	0.000
M51.8 Other specified intervertebral disk disorders	0.000	0.998	0.002
D57 Sickle-cell disorders	0.000	0.998	0.002
O16 Unspecified maternal hypertension	0.002	0.998	0.000
E16.0 Drug-induced hypoglycaemia without coma	0.000	0.998	0.002
O10 Pre-existing hypertension complicating pregnancy, childbirth and the puerperium	0.002	0.998	0.000
D22.4 Melanocytic naevi of scalp and neck	0.000	0.998	0.002
I44.7 Left bundle-branch block, unspecified	0.002	0.998	0.000
S32.00 Fracture of lumbar vertebra (closed)	0.000	0.998	0.002
D11.0 Parotid gland	0.002	0.998	0.000
G35 Multiple sclerosis	0.002	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations