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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs5003265
log Bayes Factor = 46.0369
Chromosome 6   position 29,344,036  (GRCh37) Explore rs5003265 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E83.1 Disorders of iron metabolism
1.000 0.000 0.000
K90.0 Coeliac disease
0.000 0.000 1.000
E05.9 Thyrotoxicosis, unspecified
0.000 0.009 0.991
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.013 0.987
E10 Insulin-dependent diabetes mellitus
0.000 0.019 0.981
E10.9 Without complications
0.000 0.020 0.980
E10-E14 Diabetes mellitus
0.000 0.032 0.968
E16.2 Hypoglycaemia, unspecified
0.000 0.034 0.966
E16 Other disorders of pancreatic internal secretion
0.000 0.035 0.965
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.036 0.964
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.037 0.963
E00-E07 Disorders of thyroid gland
0.000 0.039 0.961
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.041 0.959
E10.3 With ophthalmic complications
0.000 0.066 0.934
E10.2 With renal complications
0.000 0.085 0.915
E10.4 With neurological complications
0.000 0.107 0.893
E13 Other specified diabetes mellitus
0.000 0.200 0.800
E05.8 Other thyrotoxicosis
0.000 0.205 0.795
E10.1 With ketoacidosis
0.000 0.207 0.793
E16.1 Other hypoglycaemia
0.000 0.211 0.789
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.222 0.778
E05.5 Thyroid crisis or storm
0.000 0.293 0.707
E05.4 Thyrotoxicosis factitia
0.000 0.293 0.707
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.293 0.707
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.293 0.707
E10.6 With other specified complications
0.000 0.301 0.699
E12 Malnutrition-related diabetes mellitus
0.000 0.306 0.694
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.308 0.692
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.308 0.692
E16.4 Abnormal secretion of gastrin
0.000 0.308 0.692
E16.3 Increased secretion of glucagon
0.000 0.308 0.692
E10.0 With coma
0.000 0.309 0.691
E15 Nondiabetic hypoglycaemic coma
0.000 0.309 0.691
E13.9 Without complications
0.000 0.309 0.691
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.311 0.689
E00 Congenital iodine-deficiency syndrome
0.000 0.311 0.689
E14 Unspecified diabetes mellitus
0.000 0.320 0.680
E10.7 With multiple complications
0.000 0.327 0.673
E40-E46 Malnutrition
0.000 0.385 0.614
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.423 0.576
E13.8 With unspecified complications
0.000 0.426 0.573
E13.7 With multiple complications
0.000 0.426 0.573
E13.6 With other specified complications
0.000 0.426 0.573
E13.5 With peripheral circulatory complications
0.000 0.426 0.573
E13.4 With neurological complications
0.000 0.426 0.573
E13.2 With renal complications
0.000 0.426 0.573
E13.1 With ketoacidosis
0.000 0.426 0.573
E13.0 With coma
0.000 0.426 0.573
E14.3 With ophthalmic complications
0.000 0.440 0.560
I83.9 Varicose veins of lower extremities without ulcer or inflammation
0.557 0.443 0.000
E13.3 With ophthalmic complications
0.000 0.450 0.550
E14.6 With other specified complications
0.000 0.454 0.546
E07 Other disorders of thyroid
0.000 0.454 0.545
E06 Thyroiditis
0.000 0.456 0.544
E14.8 With unspecified complications
0.000 0.458 0.542
E10.5 With peripheral circulatory complications
0.000 0.465 0.535
E14.4 With neurological complications
0.000 0.484 0.516
E14.1 With ketoacidosis
0.000 0.492 0.508
E12.9 Without complications
0.000 0.502 0.497
E12.8 With unspecified complications
0.000 0.502 0.497
E12.7 With multiple complications
0.000 0.502 0.497
E12.6 With other specified complications
0.000 0.502 0.497
E12.5 With peripheral circulatory complications
0.000 0.502 0.497
E12.4 With neurological complications
0.000 0.502 0.497
E12.3 With ophthalmic complications
0.000 0.502 0.497
E12.2 With renal complications
0.000 0.502 0.497
E12.1 With ketoacidosis
0.000 0.502 0.497
E12.0 With coma
0.000 0.502 0.497
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.506 0.494
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.506 0.494
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.506 0.494
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.506 0.494
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.506 0.494
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.506 0.494
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.506 0.494
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.506 0.494
E14.7 With multiple complications
0.000 0.513 0.487
E14.0 With coma
0.000 0.513 0.487
E14.2 Withrenal complications
0.000 0.540 0.460
E10.8 With unspecified complications
0.001 0.547 0.452
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.559 0.441
E45 Retarded development following protein-energy malnutrition
0.000 0.559 0.441
E43 Unspecified severe protein-energy malnutrition
0.000 0.559 0.441
E42 Marasmic kwashiorkor
0.000 0.559 0.441
E41 Nutritional marasmus
0.000 0.559 0.441
E40 Kwashiorkor
0.000 0.559 0.441
E14.5 With peripheral circulatory complications
0.000 0.565 0.435
K90 Intestinal malabsorption
0.000 0.565 0.435
E06.9 Thyroiditis, unspecified
0.000 0.572 0.428
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.572 0.427
E07.8 Other specified disorders of thyroid
0.000 0.578 0.422
E06.1 Subacute thyroiditis
0.000 0.593 0.406
E07.1 Dyshormogenetic goitre
0.000 0.609 0.391
E07.0 Hypersecretion of calcitonin
0.000 0.609 0.391
E06.4 Drug-induced thyroiditis
0.000 0.610 0.390
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.610 0.390
E06.0 Acute thyroiditis
0.000 0.610 0.390
E06.5 Other chronic thyroiditis
0.000 0.611 0.389
E46 Unspecified protein-energy malnutrition
0.000 0.635 0.364
E03 Other hypothyroidism
0.000 0.648 0.352
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.649 0.351
E50-E64 Other nutritional deficiencies
0.000 0.660 0.340
E65-E68 Obesity and other hyperalimentation
0.000 0.669 0.331
E44.1 Mild protein-energy malnutrition
0.000 0.684 0.316
E44.0 Moderate protein-energy malnutrition
0.000 0.684 0.316
K90.3 Pancreatic steatorrhoea
0.000 0.688 0.312
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.688 0.312
K90.1 Tropical sprue
0.000 0.688 0.312
K90.9 Intestinal malabsorption, unspecified
0.000 0.708 0.292
K90.8 Other intestinal malabsorption
0.000 0.720 0.280
E83 Disorders of mineral metabolism
0.268 0.731 0.001
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.743 0.256
E03.5 Myxoedema coma
0.000 0.747 0.252
E03.4 Atrophy of thyroid (acquired)
0.000 0.747 0.252
E03.3 Postinfectious hypothyroidism
0.000 0.747 0.252
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.748 0.252
E03.1 Congenital hypothyroidism without goitre
0.000 0.749 0.251
E51 Thiamine deficiency
0.000 0.752 0.248
E83.3 Disorders of phosphorus metabolism
0.244 0.756 0.000
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.756 0.244
E50 Vitamin A deficiency
0.000 0.756 0.244
E60 Dietary zinc deficiency
0.000 0.756 0.244
E59 Dietary selenium deficiency
0.000 0.756 0.244
E54 Ascorbic acid deficiency
0.000 0.756 0.244
E52 Niacin deficiency [pellagra]
0.000 0.756 0.244
E67 Other hyperalimentation
0.000 0.762 0.237
E68 Sequelae of hyperalimentation
0.000 0.762 0.237
E56 Other vitamin deficiencies
0.000 0.771 0.229
E58 Dietary calcium deficiency
0.000 0.780 0.220
E63 Other nutritional deficiencies
0.000 0.780 0.219
E61 Deficiency of other nutrient elements
0.000 0.783 0.217
E03.8 Other specified hypothyroidism
0.000 0.784 0.216
E55 Vitamin D deficiency
0.000 0.788 0.212
E65 Localised adiposity
0.000 0.804 0.196
E83.9 Disorder of mineral metabolism, unspecified
0.193 0.807 0.001
E83.8 Other disorders of mineral metabolism
0.192 0.807 0.001
E83.2 Disorders of zinc metabolism
0.192 0.807 0.001
E83.0 Disorders of copper metabolism
0.192 0.807 0.001
E53 Deficiency of other B group vitamins
0.000 0.813 0.187
E51.2 Wernicke's encephalopathy
0.000 0.818 0.182
E51.9 Thiamine deficiency, unspecified
0.000 0.822 0.178
E51.8 Other manifestations of thiamine deficiency
0.000 0.822 0.178
E51.1 Beriberi
0.000 0.822 0.178
E50.9 Vitamin A deficiency, unspecified
0.000 0.825 0.175
E50.8 Other manifestations of vitamin A deficiency
0.000 0.825 0.175
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.825 0.175
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.825 0.175
E50.5 Vitamin A deficiency with night blindness
0.000 0.825 0.175
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.825 0.175
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.825 0.175
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.825 0.175
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.825 0.175
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.825 0.175
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.825 0.175
E64.8 Sequelae of other nutritional deficiencies
0.000 0.825 0.175
E64.3 Sequelae of rickets
0.000 0.825 0.175
E64.2 Sequelae of vitamin C deficiency
0.000 0.825 0.175
E64.1 Sequelae of vitamin A deficiency
0.000 0.825 0.175
E64.0 Sequelae of protein-energy malnutrition
0.000 0.825 0.175
E07.9 Disorder of thyroid, unspecified
0.000 0.825 0.175
E67.8 Other specified hyperalimentation
0.000 0.829 0.170
E67.3 Hypervitaminosis D
0.000 0.829 0.170
E67.2 Megavitamin-B6 syndrome
0.000 0.829 0.170
E67.1 Hypercarotenaemia
0.000 0.829 0.170
E67.0 Hypervitaminosis A
0.000 0.829 0.170
E56.9 Vitamin deficiency, unspecified
0.000 0.836 0.164
E56.8 Deficiency of other vitamins
0.000 0.836 0.164
E56.0 Deficiency of vitamin E
0.000 0.836 0.164
E63.8 Other specified nutritional deficiencies
0.000 0.842 0.157
E63.1 Imbalance of constituents of food intake
0.000 0.842 0.157
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.842 0.157
E61.1 Iron deficiency
0.000 0.844 0.156
E61.9 Deficiency of nutrient element, unspecified
0.000 0.844 0.156
E61.8 Deficiency of other specified nutrient elements
0.000 0.844 0.156
E61.7 Deficiency of multiple nutrient elements
0.000 0.844 0.156
E61.6 Vanadium deficiency
0.000 0.844 0.156
E61.5 Molybdenum deficiency
0.000 0.844 0.156
E61.4 Chromium deficiency
0.000 0.844 0.156
E61.3 Manganese deficiency
0.000 0.844 0.156
E61.0 Copper deficiency
0.000 0.844 0.156
E55.0 Rickets, active
0.000 0.847 0.152
E56.1 Deficiency of vitamin K
0.000 0.851 0.149
E53.9 Vitamin B deficiency, unspecified
0.000 0.855 0.145
E53.1 Pyridoxine deficiency
0.000 0.866 0.134
E53.0 Riboflavin deficiency
0.000 0.866 0.134
E63.9 Nutritional deficiency, unspecified
0.000 0.867 0.133
E61.2 Magnesium deficiency
0.000 0.871 0.128
E11 Non-insulin-dependent diabetes mellitus
0.000 0.872 0.128
E83.4 Disorders of magnesium metabolism
0.121 0.878 0.000
E55.9 Vitamin D deficiency, unspecified
0.000 0.879 0.121
E11.6 With other specified complications
0.000 0.881 0.119
E06.3 Autoimmune thyroiditis
0.001 0.897 0.102
C19 Malignant neoplasm of rectosigmoid junction
0.000 0.900 0.100
E11.1 With ketoacidosis
0.000 0.903 0.097
E11.7 With multiple complications
0.000 0.908 0.092
C20 Malignant neoplasm of rectum
0.000 0.912 0.088
E11.8 With unspecified complications
0.000 0.916 0.084
C15-C26 Malignant neoplasms of digestive organs
0.000 0.917 0.083
C15 Malignant neoplasm of oesophagus
0.000 0.917 0.082
E11.2 With renal complications
0.000 0.920 0.080
C15.4 Middle third of oesophagus
0.000 0.922 0.078
I83 Varicose veins of lower extremities
0.078 0.922 0.000
E14.9 Without complications
0.000 0.923 0.077
C15.5 Lower third of oesophagus
0.000 0.924 0.076
E11.0 With coma
0.000 0.925 0.075
E20-E35 Disorders of other endocrine glands
0.000 0.929 0.071
C25 Malignant neoplasm of pancreas
0.000 0.935 0.065
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.000 0.937 0.063
C17 Malignant neoplasm of small intestine
0.000 0.938 0.062
C15.9 Oesophagus, unspecified
0.000 0.938 0.062
C15.0 Cervical part of oesophagus
0.000 0.939 0.061
C15.8 Overlapping lesion of oesophagus
0.000 0.941 0.059
C15.2 Abdominal part of oesophagus
0.000 0.941 0.059
E24 Cushing's syndrome
0.000 0.941 0.059
C17.0 Duodenum
0.000 0.942 0.058
C15.1 Thoracic part of oesophagus
0.000 0.943 0.057
C24.0 Extrahepatic bile duct
0.000 0.943 0.057
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.945 0.055
C15.3 Upper third of oesophagus
0.000 0.946 0.054
C25.3 Pancreatic duct
0.000 0.946 0.054
C25.1 Body of pancreas
0.000 0.947 0.053
I83.2 Varicose veins of lower extremities with both ulcer and inflammation
0.052 0.948 0.000
E11.5 With peripheral circulatory complications
0.000 0.948 0.052
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.949 0.051
E32 Diseases of thymus
0.000 0.949 0.051
E30 Disorders of puberty, not elsewhere classified
0.000 0.949 0.051
E21.3 Hyperparathyroidism, unspecified
0.000 0.949 0.051
E11.3 With ophthalmic complications
0.000 0.949 0.051
E20 Hypoparathyroidism
0.000 0.949 0.050
C25.8 Overlapping lesion of pancreas
0.000 0.950 0.050
C25.4 Endocrine pancreas
0.000 0.950 0.050
E25 Adrenogenital disorders
0.000 0.951 0.049
E31 Polyglandular dysfunction
0.000 0.952 0.048
I83.0 Varicose veins of lower extremities with ulcer
0.048 0.952 0.000
C25.2 Tail of pancreas
0.000 0.953 0.047
E53.8 Deficiency of other specified B group vitamins
0.000 0.953 0.047
E24.2 Drug-induced Cushing's syndrome
0.000 0.953 0.047
E24.0 Pituitary-dependent Cushing's disease
0.000 0.954 0.046
C24.9 Biliary tract, unspecified
0.000 0.954 0.046
C24.8 Overlapping lesion of biliary tract
0.000 0.954 0.045
C17.1 Jejunum
0.000 0.955 0.045
E29 Testicular dysfunction
0.000 0.955 0.045
C17.8 Overlapping lesion of small intestine
0.000 0.955 0.045
C17.3 Meckel's diverticulum
0.000 0.955 0.045
E24.8 Other Cushing's syndrome
0.000 0.955 0.045
E04 Other non-toxic goitre
0.004 0.956 0.040
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.000 0.956 0.044
E22 Hyperfunction of pituitary gland
0.000 0.956 0.044
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.957 0.043
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.957 0.043
E24.3 Ectopic ACTH syndrome
0.000 0.957 0.043
E24.1 Nelson's syndrome
0.000 0.957 0.043
E24.9 Cushing's syndrome, unspecified
0.000 0.958 0.042
C25.9 Pancreas, unspecified
0.000 0.959 0.041
C25.7 Other parts of pancreas
0.000 0.960 0.040
E28 Ovarian dysfunction
0.000 0.960 0.040
E21.4 Other specified disorders of parathyroid gland
0.000 0.961 0.039
C26 Malignant neoplasm of other and ill-defined digestive organs
0.000 0.961 0.039
E21.2 Other hyperparathyroidism
0.000 0.961 0.039
K14.8 Other diseases of tongue
0.000 0.962 0.038
C18.9 Colon, unspecified
0.000 0.962 0.038
C17.9 Small intestine, unspecified
0.000 0.963 0.037
E34 Other endocrine disorders
0.000 0.963 0.037
E30.9 Disorder of puberty, unspecified
0.000 0.963 0.037
E30.8 Other disorders of puberty
0.000 0.963 0.037
E30.1 Precocious puberty
0.000 0.963 0.037
E30.0 Delayed puberty
0.000 0.963 0.037
E32.9 Disease of thymus, unspecified
0.000 0.963 0.037
E32.8 Other diseases of thymus
0.000 0.963 0.037
E32.1 Abscess of thymus
0.000 0.963 0.037
E32.0 Persistent hyperplasia of thymus
0.000 0.963 0.037
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.963 0.037
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.963 0.037
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.963 0.037
E20.8 Other hypoparathyroidism
0.000 0.963 0.036
E20.1 Pseudohypoparathyroidism
0.000 0.963 0.036
E20.0 Idiopathic hypoparathyroidism
0.000 0.963 0.036
E22.1 Hyperprolactinaemia
0.000 0.964 0.036
E20.9 Hypoparathyroidism, unspecified
0.000 0.964 0.036
C25.0 Head of pancreas
0.000 0.964 0.036
E25.9 Adrenogenital disorder, unspecified
0.000 0.965 0.035
E25.8 Other adrenogenital disorders
0.000 0.965 0.035
C18 Malignant neoplasm of colon
0.000 0.965 0.035
E11.4 With neurological complications
0.000 0.965 0.035
E31.9 Polyglandular dysfunction, unspecified
0.000 0.965 0.035
E31.8 Other polyglandular dysfunction
0.000 0.965 0.035
E31.1 Polyglandular hyperfunction
0.000 0.965 0.035
E26 Hyperaldosteronism
0.000 0.965 0.035
C23 Malignant neoplasm of gallbladder
0.000 0.965 0.034
C22.9 Liver, unspecified
0.000 0.966 0.034
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.967 0.033
E29.9 Testicular dysfunction, unspecified
0.000 0.967 0.033
E29.8 Other testicular dysfunction
0.000 0.967 0.032
E29.0 Testicular hyperfunction
0.000 0.967 0.032
E31.0 Autoimmune polyglandular failure
0.000 0.968 0.032
E04.8 Other specified non-toxic goitre
0.003 0.968 0.029
C22.7 Other specified carcinomas of liver
0.000 0.968 0.032
C22.4 Other sarcomas of liver
0.000 0.968 0.032
C22.3 Angiosarcoma of liver
0.000 0.968 0.032
C22.2 Hepatoblastoma
0.000 0.968 0.032
E22.8 Other hyperfunction of pituitary gland
0.000 0.968 0.032
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.968 0.032
C22.1 Intrahepatic bile duct carcinoma
0.000 0.969 0.031
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.969 0.031
C18.1 Appendix
0.000 0.970 0.030
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.970 0.029
R31 Unspecified haematuria
0.029 0.971 0.000
E28.9 Ovarian dysfunction, unspecified
0.000 0.971 0.029
E28.8 Other ovarian dysfunction
0.000 0.971 0.029
E28.1 Androgen excess
0.000 0.971 0.029
E28.0 Oestrogen excess
0.000 0.971 0.029
C26.8 Overlapping lesion of digestive system
0.000 0.971 0.028
C26.1 Spleen
0.000 0.971 0.028
C21 Malignant neoplasm of anus and anal canal
0.000 0.972 0.028
E34.3 Short stature, not elsewhere classified
0.000 0.973 0.027
C18.8 Overlapping lesion of colon
0.000 0.973 0.027
E34.5 Androgen resistance syndrome
0.000 0.973 0.027
E34.4 Constitutional tall stature
0.000 0.973 0.027
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.973 0.027
E34.1 Other hypersecretion of intestinal hormones
0.000 0.973 0.027
E29.1 Testicular hypofunction
0.000 0.974 0.026
K90-K93 Other diseases of the digestive system
0.000 0.974 0.026
E34.9 Endocrine disorder, unspecified
0.000 0.974 0.025
E26.8 Other hyperaldosteronism
0.000 0.975 0.025
E26.1 Secondary hyperaldosteronism
0.000 0.975 0.025
C17.2 Ileum
0.000 0.975 0.024
E28.3 Primary ovarian failure
0.000 0.976 0.024
E28.2 Polycystic ovarian syndrome
0.000 0.976 0.024
C24.1 Ampulla of Vater
0.001 0.976 0.023
E03.9 Hypothyroidism, unspecified
0.000 0.976 0.024
E23 Hypofunction and other disorders of pituitary gland
0.000 0.977 0.023
E26.9 Hyperaldosteronism, unspecified
0.000 0.977 0.023
E04.0 Non-toxic diffuse goitre
0.004 0.977 0.019
H40.2 Primary angle-closure glaucoma
0.023 0.977 0.000
E34.8 Other specified endocrine disorders
0.000 0.978 0.022
E34.0 Carcinoid syndrome
0.000 0.979 0.021
E22.0 Acromegaly and pituitary gigantism
0.000 0.979 0.021
C18.2 Ascending colon
0.000 0.979 0.021
C26.9 Ill-defined sites within the digestive system
0.000 0.979 0.021
C26.0 Intestinal tract, part unspecified
0.000 0.979 0.021
E11.9 Without complications
0.000 0.979 0.021
C21.2 Cloacogenic zone
0.000 0.980 0.020
C18.6 Descending colon
0.000 0.981 0.019
K93 Disorders of other digestive organs in diseases classified elsewhere
0.000 0.981 0.018
C21.8 Overlapping lesion of rectum, anus and anal canal
0.000 0.981 0.018
E27 Other disorders of adrenal gland
0.000 0.981 0.018
E70-E90 Metabolic disorders
0.005 0.982 0.012
C18.4 Transverse colon
0.000 0.983 0.017
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.983 0.017
E23.1 Drug-induced hypopituitarism
0.000 0.983 0.017
E23.7 Disorder of pituitary gland, unspecified
0.000 0.983 0.016
E66 Obesity
0.000 0.983 0.016
Z71.8 Other specified counselling
0.016 0.984 0.000
E21.0 Primary hyperparathyroidism
0.000 0.984 0.016
I83.1 Varicose veins of lower extremities with inflammation
0.016 0.984 0.000
H40.5 Glaucoma secondary to other eye disorders
0.015 0.985 0.000
E83.5 Disorders of calcium metabolism
0.015 0.985 0.001
C16 Malignant neoplasm of stomach
0.000 0.985 0.015
E23.2 Diabetes insipidus
0.000 0.985 0.015
K14 Diseases of tongue
0.000 0.985 0.015
E27.1 Primary adrenocortical insufficiency
0.000 0.985 0.014
C18.7 Sigmoid colon
0.000 0.986 0.014
E26.0 Primary hyperaldosteronism
0.001 0.986 0.013
K14.6 Glossodynia
0.000 0.986 0.014
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere
0.000 0.986 0.013
K93.1 Megacolon in Chagas' disease
0.000 0.986 0.013
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands
0.000 0.986 0.013
E27.5 Adrenomedullary hyperfunction
0.000 0.986 0.013
E27.0 Other adrenocortical overactivity
0.000 0.986 0.013
C18.3 Hepatic flexure
0.000 0.987 0.013
H40 Glaucoma
0.013 0.987 0.000
E23.6 Other disorders of pituitary gland
0.000 0.987 0.013
C22.0 Liver cell carcinoma
0.000 0.987 0.013
E77 Disorders of glycoprotein metabolism
0.004 0.987 0.009
E76 Disorders of glycosaminoglycan metabolism
0.004 0.987 0.009
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.004 0.987 0.009
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.004 0.987 0.009
E73 Lactose intolerance
0.003 0.987 0.010
C21.0 Anus, unspecified
0.000 0.987 0.012
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.004 0.987 0.009
E70 Disorders of aromatic amino-acid metabolism
0.004 0.988 0.009
C21.1 Anal canal
0.000 0.988 0.012
E27.9 Disorder of adrenal gland, unspecified
0.000 0.988 0.012
E72 Other disorders of amino-acid metabolism
0.004 0.988 0.008
E79 Disorders of purine and pyrimidine metabolism
0.004 0.988 0.008
E66.1 Drug-induced obesity
0.000 0.988 0.012
E78.5 Hyperlipidaemia, unspecified
0.000 0.988 0.012
E74 Other disorders of carbohydrate metabolism
0.004 0.988 0.008
E84 Cystic fibrosis
0.004 0.988 0.008
M45.X9 Ankylosing spondylitis (Site unspecified)
0.012 0.988 0.000
K14.1 Geographic tongue
0.000 0.988 0.012
K14.3 Hypertrophy of tongue papillae
0.000 0.988 0.012
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.000 0.988 0.012
E85 Amyloidosis
0.003 0.989 0.008
C16.5 Lesser curvature of stomach, unspecified
0.000 0.989 0.011
K14.5 Plicated tongue
0.000 0.989 0.011
K14.4 Atrophy of tongue papillae
0.000 0.989 0.011
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.989 0.011
C16.8 Overlapping lesion of stomach
0.000 0.989 0.011
E27.2 Addisonian crisis
0.000 0.989 0.010
E88 Other metabolic disorders
0.002 0.990 0.008
E78.1 Pure hyperglyceridaemia
0.000 0.990 0.010
E04.9 Non-toxic goitre, unspecified
0.002 0.990 0.008
E78.6 Lipoprotein deficiency
0.000 0.990 0.010
C16.1 Fundus of stomach
0.000 0.990 0.010
E78.2 Mixed hyperlipidaemia
0.000 0.990 0.010
C16.2 Body of stomach
0.000 0.990 0.010
C16.9 Stomach, unspecified
0.000 0.990 0.010
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.990 0.010
K14.2 Median rhomboid glossitis
0.000 0.990 0.010
C16.6 Greater curvature of stomach, unspecified
0.000 0.990 0.010
I97.2 Postmastectomy lymphoedema syndrome
0.000 0.990 0.010
H40.4 Glaucoma secondary to eye inflammation
0.010 0.990 0.000
H40.3 Glaucoma secondary to eye trauma
0.010 0.990 0.000
H40.6 Glaucoma secondary to drugs
0.010 0.990 0.000
C16.4 Pylorus
0.000 0.990 0.009
C18.5 Splenic flexure
0.000 0.990 0.009
E71.3 Disorders of fatty-acid metabolism
0.003 0.990 0.007
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified
0.003 0.990 0.007
E71.1 Other disorders of branched-chain amino-acid metabolism
0.003 0.990 0.007
E71.0 Maple-syrup-urine disease
0.003 0.990 0.007
E76.9 Disorder of glucosaminoglycan metabolism, unspecified
0.003 0.990 0.007
E76.8 Other disorders of glucosaminoglycan metabolism
0.003 0.990 0.007
E76.3 Mucopolysaccharidosis, unspecified
0.003 0.990 0.007
E76.2 Other mucopolysaccharidoses
0.003 0.990 0.007
E76.1 Mucopolysaccharidosis, type II
0.003 0.990 0.007
E76.0 Mucopolysaccharidosis, type I
0.003 0.990 0.007
E77.9 Disorder of glycoprotein metabolism, unspecified
0.003 0.990 0.007
E77.8 Other disorders of glycoprotein metabolism
0.003 0.990 0.007
E77.1 Defects in glycoprotein degradation
0.003 0.990 0.007
E77.0 Defects in posttranslational modification of lysosomal enzymes
0.003 0.990 0.007
E73.8 Other lactose intolerance
0.002 0.991 0.007
E73.1 Secondary lactase deficiency
0.002 0.991 0.007
E73.0 Congenital lactase deficiency
0.002 0.991 0.007
E75.6 Lipid storage disorder, unspecified
0.003 0.991 0.007
E75.4 Neuronal ceroid lipofuscinosis
0.003 0.991 0.007
E75.3 Sphingolipidosis, unspecified
0.003 0.991 0.007
E75.1 Other gangliosidosis
0.003 0.991 0.007
E75.0 GM2 gangliosidosis
0.003 0.991 0.007
E75.5 Other lipid storage disorders
0.003 0.991 0.007
E73.9 Lactose intolerance, unspecified
0.001 0.991 0.008
E70.9 Disorder of aromatic amino-acid metabolism, unspecified
0.003 0.991 0.006
E70.8 Other disorders of aromatic amino-acid metabolism
0.003 0.991 0.006
E70.2 Disorders of tyrosine metabolism
0.003 0.991 0.006
E70.1 Other hyperphenylalaninaemias
0.003 0.991 0.006
E70.0 Classical phenylketonuria
0.003 0.991 0.006
E72.9 Disorder of amino-acid metabolism, unspecified
0.003 0.991 0.006
E72.8 Other specified disorders of amino-acid metabolism
0.003 0.991 0.006
E72.5 Disorders of glycine metabolism
0.003 0.991 0.006
E72.4 Disorders of ornithine metabolism
0.003 0.991 0.006
E72.3 Disorders of lysine and hydroxylysine metabolism
0.003 0.991 0.006
E72.2 Disorders of urea cycle metabolism
0.003 0.991 0.006
C18.0 Caecum
0.000 0.991 0.009
E75.2 Other sphingolipidosis
0.003 0.991 0.006
E72.0 Disorders of amino-acid transport
0.003 0.991 0.006
E79.9 Disorder of purine and pyrimidine metabolism, unspecified
0.003 0.991 0.006
E79.8 Other disorders of purine and pyrimidine metabolism
0.003 0.991 0.006
E79.1 Lesch-Nyhan syndrome
0.003 0.991 0.006
E74.9 Disorder of carbohydrate metabolism, unspecified
0.003 0.991 0.006
E74.8 Other specified disorders of carbohydrate metabolism
0.003 0.991 0.006
E74.4 Disorders of pyruvate metabolism and gluconeogenesis
0.003 0.991 0.006
E74.2 Disorders of galactose metabolism
0.003 0.991 0.006
E74.1 Disorders of fructose metabolism
0.003 0.991 0.006
E74.0 Glycogen storage disease
0.003 0.991 0.006
E84.8 Cystic fibrosis with other manifestations
0.003 0.991 0.006
E84.1 Cystic fibrosis with intestinal manifestations
0.003 0.991 0.006
E70.3 Albinism
0.003 0.991 0.006
E27.8 Other specified disorders of adrenal gland
0.000 0.991 0.009
H40.8 Other glaucoma
0.009 0.991 0.000
E72.1 Disorders of sulphur-bearing amino-acid metabolism
0.003 0.991 0.005
E84.0 Cystic fibrosis with pulmonary manifestations
0.003 0.991 0.006
K14.0 Glossitis
0.000 0.991 0.009
E78.3 Hyperchylomicronaemia
0.000 0.991 0.009
E88.9 Metabolic disorder, unspecified
0.001 0.992 0.007
E85.8 Other amyloidosis
0.003 0.992 0.006
E85.2 Heredofamilial amyloidosis, unspecified
0.003 0.992 0.006
E85.1 Neuropathic heredofamilial amyloidosis
0.003 0.992 0.006
E85.0 Nonneuropathic heredofamilial amyloidosis
0.003 0.992 0.006
K40.9 Unilateral or unspecified inguinal hernia, without obstruction or gangrene
0.008 0.992 0.000
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease
0.003 0.992 0.005
E85.3 Secondary systemic amyloidosis
0.002 0.992 0.006
E80 Disorders of porphyrin and bilirubin metabolism
0.004 0.992 0.004
S02.40 Fracture of malar and maxillary bones (closed)
0.000 0.992 0.008
E84.9 Cystic fibrosis, unspecified
0.004 0.992 0.005
E85.4 Organ-limited amyloidosis
0.002 0.992 0.006
E74.3 Other disorders of intestinal carbohydrate absorption
0.003 0.992 0.005
C16.3 Pyloric antrum
0.000 0.992 0.008
C16.0 Cardia
0.000 0.992 0.008
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.000 0.992 0.008
E66.0 Obesity due to excess calories
0.001 0.992 0.007
E23.0 Hypopituitarism
0.000 0.992 0.008
E88.2 Lipomatosis, not elsewhere classified
0.001 0.992 0.006
E88.1 Lipodystrophy, not elsewhere classified
0.002 0.992 0.006
E78.9 Disorder of lipoprotein metabolism, unspecified
0.000 0.992 0.008
E78.4 Other hyperlipidaemia
0.000 0.992 0.008
W22 Striking against or struck by other objects
0.000 0.992 0.008
E04.1 Non-toxic single thyroid nodule
0.004 0.993 0.003
I97.8 Other postprocedural disorders of circulatory system, not elsewhere classified
0.000 0.993 0.007
H40.0 Glaucoma suspect
0.007 0.993 0.000
E66.2 Extreme obesity with alveolar hypoventilation
0.001 0.993 0.007

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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