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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs5025315
log Bayes Factor = 109.014
Chromosome 6   position 31,343,604  (GRCh37) Explore rs5025315 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E10.9 Without complications
0.000 0.000 1.000
J45.9 Asthma, unspecified
0.000 0.000 1.000
K51.9 Ulcerative colitis, unspecified
1.000 0.000 0.000
K90.0 Coeliac disease
0.000 0.000 1.000
M45.X9 Ankylosing spondylitis (Site unspecified)
1.000 0.000 0.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
E10.3 With ophthalmic complications
0.000 0.000 1.000
K51 Ulcerative colitis
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.000 1.000
E14 Unspecified diabetes mellitus
0.000 0.000 1.000
E16.2 Hypoglycaemia, unspecified
0.000 0.000 1.000
E16 Other disorders of pancreatic internal secretion
0.000 0.000 1.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.000 1.000
E14.9 Without complications
0.000 0.001 0.999
E83.1 Disorders of iron metabolism
0.999 0.001 0.000
M45 Ankylosing spondylitis
0.999 0.001 0.000
E11 Non-insulin-dependent diabetes mellitus
0.000 0.002 0.998
M45.X0 Ankylosing spondylitis (Multiple sites in spine)
0.998 0.002 0.000
E10.1 With ketoacidosis
0.000 0.002 0.998
K51.4 Pseudopolyposis of colon
0.995 0.005 0.000
E10.4 With neurological complications
0.000 0.014 0.986
M06.9 Rheumatoid arthritis, unspecified
0.000 0.015 0.985
E20-E35 Disorders of other endocrine glands
0.000 0.016 0.984
K51.2 Ulcerative (chronic) proctitis
0.981 0.019 0.000
G35 Multiple sclerosis
0.976 0.024 0.000
E00-E07 Disorders of thyroid gland
0.000 0.025 0.975
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.025 0.975
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.026 0.974
K51.3 Ulcerative (chronic) rectosigmoiditis
0.973 0.027 0.000
E05.9 Thyrotoxicosis, unspecified
0.000 0.030 0.970
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.033 0.967
E11.1 With ketoacidosis
0.000 0.045 0.955
E27 Other disorders of adrenal gland
0.000 0.046 0.954
E11.3 With ophthalmic complications
0.000 0.056 0.944
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.063 0.937
E10.0 With coma
0.000 0.064 0.936
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.065 0.935
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.079 0.921
E11.0 With coma
0.000 0.079 0.921
E10.8 With unspecified complications
0.000 0.093 0.907
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.093 0.907
E27.1 Primary adrenocortical insufficiency
0.000 0.114 0.886
E11.9 Without complications
0.000 0.118 0.882
E14.1 With ketoacidosis
0.000 0.126 0.874
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.127 0.873
K51.8 Other ulcerative colitis
0.868 0.132 0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.133 0.867
K51.5 Mucosal proctocolitis
0.862 0.138 0.000
E10.6 With other specified complications
0.000 0.138 0.862
E10.2 With renal complications
0.000 0.147 0.853
E14.3 With ophthalmic complications
0.000 0.152 0.848
E11.5 With peripheral circulatory complications
0.000 0.155 0.845
E23 Hypofunction and other disorders of pituitary gland
0.000 0.156 0.844
E22 Hyperfunction of pituitary gland
0.000 0.157 0.843
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.163 0.837
E10.5 With peripheral circulatory complications
0.000 0.173 0.827
E14.6 With other specified complications
0.000 0.174 0.826
M45.X2 Ankylosing spondylitis (Cervical region)
0.825 0.175 0.000
E27.9 Disorder of adrenal gland, unspecified
0.000 0.184 0.816
E24 Cushing's syndrome
0.000 0.188 0.812
E13 Other specified diabetes mellitus
0.000 0.191 0.809
M45.X7 Ankylosing spondylitis (Lumbosacral region)
0.808 0.192 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.788 0.212 0.000
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.217 0.783
E16.1 Other hypoglycaemia
0.000 0.219 0.780
M45.X6 Ankylosing spondylitis (Lumbar region)
0.779 0.221 0.000
E05.8 Other thyrotoxicosis
0.000 0.224 0.776
E40-E46 Malnutrition
0.000 0.225 0.774
E14.2 Withrenal complications
0.000 0.226 0.774
E23.2 Diabetes insipidus
0.000 0.231 0.769
J45 Asthma
0.000 0.251 0.749
E07 Other disorders of thyroid
0.000 0.257 0.743
G37 Other demyelinating diseases of central nervous system
0.742 0.258 0.000
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.261 0.739
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.269 0.731
E14.8 With unspecified complications
0.000 0.277 0.723
E28 Ovarian dysfunction
0.000 0.282 0.718
E10.7 With multiple complications
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
E14.7 With multiple complications
0.000 0.283 0.717
E14.0 With coma
0.000 0.283 0.717
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.283 0.717
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.283 0.717
E16.4 Abnormal secretion of gastrin
0.000 0.283 0.717
E16.3 Increased secretion of glucagon
0.000 0.283 0.717
E15 Nondiabetic hypoglycaemic coma
0.000 0.283 0.717
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)
0.716 0.284 0.000
M45.X5 Ankylosing spondylitis (Thoracolumbar region)
0.716 0.284 0.000
M45.X4 Ankylosing spondylitis (Thoracic region)
0.716 0.284 0.000
M45.X3 Ankylosing spondylitis (Cervicothoracic region)
0.716 0.284 0.000
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)
0.716 0.284 0.000
E11.7 With multiple complications
0.000 0.284 0.716
E25 Adrenogenital disorders
0.000 0.289 0.711
G37.9 Demyelinating disease of central nervous system, unspecified
0.709 0.291 0.000
E34 Other endocrine disorders
0.000 0.291 0.709
E24.0 Pituitary-dependent Cushing's disease
0.000 0.292 0.708
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.294 0.706
E32 Diseases of thymus
0.000 0.294 0.706
E30 Disorders of puberty, not elsewhere classified
0.000 0.294 0.706
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.294 0.706
M06 Other rheumatoid arthritis
0.009 0.299 0.691
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.301 0.699
E00 Congenital iodine-deficiency syndrome
0.000 0.301 0.699
E05.5 Thyroid crisis or storm
0.000 0.301 0.699
E05.4 Thyrotoxicosis factitia
0.000 0.301 0.699
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.301 0.699
E14.5 With peripheral circulatory complications
0.000 0.302 0.698
E22.0 Acromegaly and pituitary gigantism
0.000 0.303 0.697
K51.0 Ulcerative (chronic) enterocolitis
0.692 0.308 0.000
E29 Testicular dysfunction
0.000 0.310 0.690
E31 Polyglandular dysfunction
0.000 0.314 0.686
E11.4 With neurological complications
0.000 0.314 0.686
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.314 0.686
E27.5 Adrenomedullary hyperfunction
0.000 0.316 0.684
E27.0 Other adrenocortical overactivity
0.000 0.316 0.684
E13.9 Without complications
0.000 0.318 0.682
M06.3 Rheumatoid nodule
0.002 0.323 0.675
E20 Hypoparathyroidism
0.000 0.326 0.674
E23.7 Disorder of pituitary gland, unspecified
0.000 0.329 0.671
E26 Hyperaldosteronism
0.000 0.338 0.662
E14.4 With neurological complications
0.000 0.351 0.649
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.351 0.649
E11.8 With unspecified complications
0.000 0.352 0.648
K90 Intestinal malabsorption
0.000 0.352 0.648
M06.34 Rheumatoid nodule (Hand)
0.001 0.364 0.635
E11.6 With other specified complications
0.000 0.366 0.634
E27.8 Other specified disorders of adrenal gland
0.000 0.366 0.634
J45.0 Predominantly allergic asthma
0.000 0.367 0.633
J45.1 Nonallergic asthma
0.000 0.381 0.619
E46 Unspecified protein-energy malnutrition
0.000 0.387 0.613
E07.8 Other specified disorders of thyroid
0.000 0.389 0.611
K51.1 Ulcerative (chronic) ileocolitis
0.609 0.391 0.000
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.395 0.605
E23.1 Drug-induced hypopituitarism
0.000 0.395 0.605
E22.8 Other hyperfunction of pituitary gland
0.000 0.396 0.604
E24.2 Drug-induced Cushing's syndrome
0.000 0.396 0.604
G36 Other acute disseminated demyelination
0.604 0.396 0.000
E11.2 With renal complications
0.000 0.400 0.599
E28.2 Polycystic ovarian syndrome
0.000 0.401 0.599
E23.6 Other disorders of pituitary gland
0.000 0.405 0.595
J45.8 Mixed asthma
0.000 0.405 0.595
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.406 0.594
M06.32 Rheumatoid nodule (Upper arm)
0.001 0.409 0.590
E22.1 Hyperprolactinaemia
0.000 0.415 0.584
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.417 0.582
E24.3 Ectopic ACTH syndrome
0.000 0.417 0.582
E24.1 Nelson's syndrome
0.000 0.417 0.582
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.418 0.582
E13.8 With unspecified complications
0.000 0.420 0.580
E13.7 With multiple complications
0.000 0.420 0.580
E13.6 With other specified complications
0.000 0.420 0.580
E13.5 With peripheral circulatory complications
0.000 0.420 0.580
E13.4 With neurological complications
0.000 0.420 0.580
E13.2 With renal complications
0.000 0.420 0.580
E13.1 With ketoacidosis
0.000 0.420 0.580
E13.0 With coma
0.000 0.420 0.580
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.424 0.576
G37.8 Other specified demyelinating diseases of central nervous system
0.563 0.437 0.000
E13.3 With ophthalmic complications
0.000 0.438 0.562
E24.9 Cushing's syndrome, unspecified
0.000 0.438 0.561
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.445 0.555
E45 Retarded development following protein-energy malnutrition
0.000 0.445 0.555
E43 Unspecified severe protein-energy malnutrition
0.000 0.445 0.555
E42 Marasmic kwashiorkor
0.000 0.445 0.555
E41 Nutritional marasmus
0.000 0.445 0.555
E40 Kwashiorkor
0.000 0.445 0.555
K90.9 Intestinal malabsorption, unspecified
0.000 0.446 0.554
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.461 0.539
E27.2 Addisonian crisis
0.000 0.461 0.539
E24.8 Other Cushing's syndrome
0.000 0.462 0.538
E34.9 Endocrine disorder, unspecified
0.000 0.465 0.535
M06.37 Rheumatoid nodule (Ankle and foot)
0.001 0.466 0.533
E07.1 Dyshormogenetic goitre
0.000 0.467 0.533
E07.0 Hypersecretion of calcitonin
0.000 0.467 0.533
G37.5 Concentric sclerosis [Balo]
0.532 0.468 0.000
G37.4 Subacute necrotising myelitis
0.532 0.468 0.000
G37.2 Central pontine myelinolysis
0.532 0.468 0.000
G37.1 Central demyelination of corpus callosum
0.532 0.468 0.000
G37.0 Diffuse sclerosis
0.532 0.468 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.482 0.518
E26.9 Hyperaldosteronism, unspecified
0.000 0.485 0.515
E28.9 Ovarian dysfunction, unspecified
0.000 0.485 0.515
E28.8 Other ovarian dysfunction
0.000 0.485 0.515
E28.1 Androgen excess
0.000 0.485 0.515
E28.0 Oestrogen excess
0.000 0.485 0.515
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.486 0.514
E12.9 Without complications
0.000 0.486 0.514
E12.8 With unspecified complications
0.000 0.486 0.514
E12.7 With multiple complications
0.000 0.486 0.514
E12.6 With other specified complications
0.000 0.486 0.514
E12.5 With peripheral circulatory complications
0.000 0.486 0.514
E12.4 With neurological complications
0.000 0.486 0.514
E12.3 With ophthalmic complications
0.000 0.486 0.514
E12.2 With renal complications
0.000 0.486 0.514
E12.1 With ketoacidosis
0.000 0.486 0.514
E12.0 With coma
0.000 0.486 0.514
M06.8 Other specified rheumatoid arthritis
0.006 0.489 0.504
E25.9 Adrenogenital disorder, unspecified
0.000 0.490 0.509
E25.8 Other adrenogenital disorders
0.000 0.490 0.509
K90.8 Other intestinal malabsorption
0.000 0.491 0.509
E34.0 Carcinoid syndrome
0.000 0.491 0.509
E34.5 Androgen resistance syndrome
0.000 0.492 0.508
E34.4 Constitutional tall stature
0.000 0.492 0.508
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.492 0.508
E34.1 Other hypersecretion of intestinal hormones
0.000 0.492 0.508
E30.9 Disorder of puberty, unspecified
0.000 0.494 0.506
E30.8 Other disorders of puberty
0.000 0.494 0.506
E30.1 Precocious puberty
0.000 0.494 0.506
E30.0 Delayed puberty
0.000 0.494 0.506
E32.9 Disease of thymus, unspecified
0.000 0.494 0.506
E32.8 Other diseases of thymus
0.000 0.494 0.506
E32.1 Abscess of thymus
0.000 0.494 0.506
E32.0 Persistent hyperplasia of thymus
0.000 0.494 0.506
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.494 0.506
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.494 0.506
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.494 0.506
M06.2 Rheumatoid bursitis
0.007 0.497 0.496
M06.1 Adult-onset Still's disease
0.007 0.497 0.496
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.498 0.501
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.498 0.501
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.498 0.501
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.498 0.501
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.498 0.501
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.498 0.501
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.498 0.501
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.498 0.501
E34.8 Other specified endocrine disorders
0.000 0.503 0.497
M06.30 Rheumatoid nodule (Multiple sites)
0.001 0.503 0.496
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.496 0.504 0.000
E29.9 Testicular dysfunction, unspecified
0.000 0.505 0.494
E29.8 Other testicular dysfunction
0.000 0.505 0.494
E29.0 Testicular hyperfunction
0.000 0.505 0.494
E31.9 Polyglandular dysfunction, unspecified
0.000 0.508 0.492
E31.8 Other polyglandular dysfunction
0.000 0.508 0.492
E31.1 Polyglandular hyperfunction
0.000 0.508 0.492
E34.3 Short stature, not elsewhere classified
0.000 0.508 0.492
M06.39 Rheumatoid nodule (Site unspecified)
0.002 0.515 0.484
M06.38 Rheumatoid nodule (Other)
0.002 0.515 0.484
M06.36 Rheumatoid nodule (Lower leg)
0.002 0.515 0.484
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.002 0.515 0.484
M06.33 Rheumatoid nodule (Forearm)
0.002 0.515 0.484
M06.31 Rheumatoid nodule (Shoulder region)
0.002 0.515 0.484
E20.8 Other hypoparathyroidism
0.000 0.516 0.483
E20.1 Pseudohypoparathyroidism
0.000 0.516 0.483
E20.0 Idiopathic hypoparathyroidism
0.000 0.516 0.483
E29.1 Testicular hypofunction
0.000 0.521 0.478
E07.9 Disorder of thyroid, unspecified
0.000 0.524 0.476
E26.8 Other hyperaldosteronism
0.000 0.525 0.475
E26.1 Secondary hyperaldosteronism
0.000 0.525 0.475
E31.0 Autoimmune polyglandular failure
0.000 0.527 0.472
G36.0 Neuromyelitis optica [Devic]
0.471 0.528 0.000
K90.3 Pancreatic steatorrhoea
0.000 0.535 0.464
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.535 0.464
K90.1 Tropical sprue
0.000 0.535 0.464
E20.9 Hypoparathyroidism, unspecified
0.000 0.548 0.452
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.554 0.446
E03 Other hypothyroidism
0.000 0.559 0.441
E06 Thyroiditis
0.000 0.559 0.440
M06.4 Inflammatory polyarthropathy
0.006 0.567 0.427
G36.9 Acute disseminated demyelination, unspecified
0.433 0.567 0.000
G36.8 Other specified acute disseminated demyelination
0.433 0.567 0.000
G36.1 Acute and subacute haemorrhagic leukoencephalitis [Hurst]
0.433 0.567 0.000
E23.0 Hypopituitarism
0.000 0.578 0.422
E44.1 Mild protein-energy malnutrition
0.000 0.602 0.398
E44.0 Moderate protein-energy malnutrition
0.000 0.602 0.398
E28.3 Primary ovarian failure
0.000 0.609 0.391
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.609 0.391
M06.89 Other specified rheumatoid arthritis (Site unspecified)
0.004 0.626 0.370
E21.4 Other specified disorders of parathyroid gland
0.000 0.629 0.371
E26.0 Primary hyperaldosteronism
0.000 0.632 0.368
M06.88 Other specified rheumatoid arthritis (Other)
0.005 0.634 0.361
M06.87 Other specified rheumatoid arthritis (Ankle and foot)
0.005 0.634 0.361
M06.86 Other specified rheumatoid arthritis (Lower leg)
0.005 0.634 0.361
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)
0.005 0.634 0.361
M06.84 Other specified rheumatoid arthritis (Hand)
0.005 0.634 0.361
M06.83 Other specified rheumatoid arthritis (Forearm)
0.005 0.634 0.361
M06.82 Other specified rheumatoid arthritis (Upper arm)
0.005 0.634 0.361
M06.81 Other specified rheumatoid arthritis (Shoulder region)
0.005 0.634 0.361
M06.80 Other specified rheumatoid arthritis (Multiple sites)
0.005 0.634 0.361
M06.19 Adult-onset Still's disease (Site unspecified)
0.005 0.640 0.356
M06.18 Adult-onset Still's disease (Other)
0.005 0.640 0.356
M06.17 Adult-onset Still's disease (Ankle and foot)
0.005 0.640 0.356
M06.16 Adult-onset Still's disease (Lower leg)
0.005 0.640 0.356
M06.15 Adult-onset Still's disease (Pelvic region and thigh)
0.005 0.640 0.356
M06.14 Adult-onset Still's disease (Hand)
0.005 0.640 0.356
M06.13 Adult-onset Still's disease (Forearm)
0.005 0.640 0.356
M06.12 Adult-onset Still's disease (Upper arm)
0.005 0.640 0.356
M06.11 Adult-onset Still's disease (Shoulder region)
0.005 0.640 0.356
M06.10 Adult-onset Still's disease (Multiple sites)
0.005 0.640 0.356
M06.29 Rheumatoid bursitis (Site unspecified)
0.005 0.640 0.356
M06.28 Rheumatoid bursitis (Other)
0.005 0.640 0.356
M06.27 Rheumatoid bursitis (Ankle and foot)
0.005 0.640 0.356
M06.26 Rheumatoid bursitis (Lower leg)
0.005 0.640 0.356
M06.25 Rheumatoid bursitis (Pelvic region and thigh)
0.005 0.640 0.356
M06.24 Rheumatoid bursitis (Hand)
0.005 0.640 0.356
M06.23 Rheumatoid bursitis (Forearm)
0.005 0.640 0.356
M06.22 Rheumatoid bursitis (Upper arm)
0.005 0.640 0.356
M06.21 Rheumatoid bursitis (Shoulder region)
0.005 0.640 0.356
M06.20 Rheumatoid bursitis (Multiple sites)
0.005 0.640 0.356
H20.9 Iridocyclitis, unspecified
0.354 0.646 0.000
E65-E68 Obesity and other hyperalimentation
0.000 0.646 0.353
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.650 0.350
E21.0 Primary hyperparathyroidism
0.000 0.654 0.346
E21.3 Hyperparathyroidism, unspecified
0.000 0.671 0.329
E21.2 Other hyperparathyroidism
0.000 0.671 0.329
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.682 0.318
E03.5 Myxoedema coma
0.000 0.684 0.316
E03.4 Atrophy of thyroid (acquired)
0.000 0.684 0.316
E03.3 Postinfectious hypothyroidism
0.000 0.684 0.316
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.684 0.316
E06.4 Drug-induced thyroiditis
0.000 0.684 0.316
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.684 0.316
E06.0 Acute thyroiditis
0.000 0.684 0.316
E06.1 Subacute thyroiditis
0.000 0.685 0.315
H20 Iridocyclitis
0.312 0.688 0.000
M06.48 Inflammatory polyarthropathy (Other)
0.005 0.689 0.306
M06.47 Inflammatory polyarthropathy (Ankle and foot)
0.005 0.689 0.306
M06.46 Inflammatory polyarthropathy (Lower leg)
0.005 0.689 0.306
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)
0.005 0.689 0.306
M06.44 Inflammatory polyarthropathy (Hand)
0.005 0.689 0.306
M06.43 Inflammatory polyarthropathy (Forearm)
0.005 0.689 0.306
M06.42 Inflammatory polyarthropathy (Upper arm)
0.005 0.689 0.306
M06.41 Inflammatory polyarthropathy (Shoulder region)
0.005 0.689 0.306
E06.5 Other chronic thyroiditis
0.000 0.698 0.302
E03.1 Congenital hypothyroidism without goitre
0.000 0.698 0.302
E03.8 Other specified hypothyroidism
0.000 0.700 0.300
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.004 0.704 0.292
K50-K52 Noninfective enteritis and colitis
0.291 0.709 0.000
E50-E64 Other nutritional deficiencies
0.000 0.713 0.287
H20.0 Acute and subacute iridocyclitis
0.273 0.727 0.000
H20.1 Chronic iridocyclitis
0.265 0.735 0.000
M06.49 Inflammatory polyarthropathy (Site unspecified)
0.004 0.738 0.258
H20.8 Other iridocyclitis
0.254 0.746 0.000
E67 Other hyperalimentation
0.000 0.746 0.253
E68 Sequelae of hyperalimentation
0.000 0.746 0.253
E06.3 Autoimmune thyroiditis
0.000 0.749 0.251
E83 Disorders of mineral metabolism
0.244 0.755 0.001
H36.0 Diabetic retinopathy
0.000 0.769 0.231
H20.2 Lens-induced iridocyclitis
0.224 0.776 0.000
E51 Thiamine deficiency
0.000 0.782 0.218
E06.9 Thyroiditis, unspecified
0.000 0.785 0.215
E58 Dietary calcium deficiency
0.000 0.792 0.208
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.794 0.206
E63 Other nutritional deficiencies
0.000 0.794 0.206
E50 Vitamin A deficiency
0.000 0.794 0.206
E60 Dietary zinc deficiency
0.000 0.794 0.206
E59 Dietary selenium deficiency
0.000 0.794 0.206
E54 Ascorbic acid deficiency
0.000 0.794 0.206
E52 Niacin deficiency [pellagra]
0.000 0.794 0.206
K50 Crohn's disease [regional enteritis]
0.204 0.796 0.000
E65 Localised adiposity
0.000 0.803 0.197
E56 Other vitamin deficiencies
0.000 0.816 0.183
E67.8 Other specified hyperalimentation
0.000 0.818 0.182
E67.3 Hypervitaminosis D
0.000 0.818 0.182
E67.2 Megavitamin-B6 syndrome
0.000 0.818 0.182
E67.1 Hypercarotenaemia
0.000 0.818 0.182
E67.0 Hypervitaminosis A
0.000 0.818 0.182
K50.9 Crohn's disease, unspecified
0.177 0.823 0.000
E83.9 Disorder of mineral metabolism, unspecified
0.175 0.824 0.001
E83.8 Other disorders of mineral metabolism
0.175 0.824 0.001
E83.2 Disorders of zinc metabolism
0.175 0.824 0.001
E83.0 Disorders of copper metabolism
0.175 0.824 0.001
E51.2 Wernicke's encephalopathy
0.000 0.831 0.169
I10 Essential (primary) hypertension
0.000 0.831 0.169
E83.3 Disorders of phosphorus metabolism
0.167 0.833 0.000
K50.1 Crohn's disease of large intestine
0.165 0.835 0.000
M07.3 Other psoriatic arthropathies
0.164 0.836 0.000
M07.30 Other psoriatic arthropathies (Multiple sites)
0.162 0.838 0.000
E51.9 Thiamine deficiency, unspecified
0.000 0.843 0.156
E51.8 Other manifestations of thiamine deficiency
0.000 0.843 0.156
E51.1 Beriberi
0.000 0.843 0.156
K52 Other non-infective gastro-enteritis and colitis
0.154 0.845 0.000
M07.39 Other psoriatic arthropathies (Site unspecified)
0.153 0.847 0.000
E61 Deficiency of other nutrient elements
0.000 0.847 0.152
E55 Vitamin D deficiency
0.000 0.848 0.152
E83.4 Disorders of magnesium metabolism
0.149 0.850 0.000
E50.9 Vitamin A deficiency, unspecified
0.000 0.852 0.148
E50.8 Other manifestations of vitamin A deficiency
0.000 0.852 0.148
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.852 0.148
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.852 0.148
E50.5 Vitamin A deficiency with night blindness
0.000 0.852 0.148
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.852 0.148
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.852 0.148
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.852 0.148
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.852 0.148
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.852 0.148
E63.9 Nutritional deficiency, unspecified
0.000 0.852 0.148
E63.8 Other specified nutritional deficiencies
0.000 0.852 0.148
E63.1 Imbalance of constituents of food intake
0.000 0.852 0.148
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.852 0.148
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.852 0.148
E64.8 Sequelae of other nutritional deficiencies
0.000 0.852 0.148
E64.3 Sequelae of rickets
0.000 0.852 0.148
E64.2 Sequelae of vitamin C deficiency
0.000 0.852 0.148
E64.1 Sequelae of vitamin A deficiency
0.000 0.852 0.148
E64.0 Sequelae of protein-energy malnutrition
0.000 0.852 0.148
K52.3 Indeterminate colitis
0.143 0.857 0.000
H36 Retinal disorders in diseases classified elsewhere
0.000 0.858 0.142
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.141 0.858 0.000
E83.5 Disorders of calcium metabolism
0.141 0.859 0.000
M45-M49 Spondylopathies
0.139 0.861 0.000
M06.0 Seronegative rheumatoid arthritis
0.008 0.862 0.129
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)
0.135 0.865 0.000
M07.34 Other psoriatic arthropathies (Hand)
0.133 0.867 0.000
E56.9 Vitamin deficiency, unspecified
0.000 0.868 0.132
E56.8 Deficiency of other vitamins
0.000 0.868 0.132
E56.0 Deficiency of vitamin E
0.000 0.868 0.132
M07.36 Other psoriatic arthropathies (Lower leg)
0.128 0.872 0.000
M07.31 Other psoriatic arthropathies (Shoulder region)
0.127 0.873 0.000
K52.1 Toxic gastro-enteritis and colitis
0.127 0.873 0.000
M07.38 Other psoriatic arthropathies (Other)
0.126 0.873 0.000
M07 Psoriatic and enteropathic arthropathies
0.114 0.875 0.011
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.121 0.879 0.000
I83.0 Varicose veins of lower extremities with ulcer
0.120 0.880 0.000
K52.0 Gastro-enteritis and colitis due to radiation
0.120 0.880 0.000
I83 Varicose veins of lower extremities
0.120 0.880 0.000
M07.33 Other psoriatic arthropathies (Forearm)
0.118 0.882 0.000
M07.32 Other psoriatic arthropathies (Upper arm)
0.118 0.882 0.000
E04 Other non-toxic goitre
0.000 0.884 0.116
I83.9 Varicose veins of lower extremities without ulcer or inflammation
0.115 0.885 0.000
K50.0 Crohn's disease of small intestine
0.114 0.886 0.000
H21 Other disorders of iris and ciliary body
0.113 0.887 0.000
H21.5 Other adhesions and disruptions of iris and ciliary body
0.113 0.887 0.000
I83.1 Varicose veins of lower extremities with inflammation
0.111 0.889 0.000
E56.1 Deficiency of vitamin K
0.001 0.890 0.109
E61.9 Deficiency of nutrient element, unspecified
0.000 0.890 0.109
E61.8 Deficiency of other specified nutrient elements
0.000 0.890 0.109
E61.7 Deficiency of multiple nutrient elements
0.000 0.890 0.109
E61.6 Vanadium deficiency
0.000 0.890 0.109
E61.5 Molybdenum deficiency
0.000 0.890 0.109
E61.4 Chromium deficiency
0.000 0.890 0.109
E61.3 Manganese deficiency
0.000 0.890 0.109
E61.0 Copper deficiency
0.000 0.890 0.109
E55.0 Rickets, active
0.000 0.890 0.109
I83.2 Varicose veins of lower extremities with both ulcer and inflammation
0.109 0.891 0.000
E53 Deficiency of other B group vitamins
0.000 0.892 0.108
M05-M14 Inflammatory polyarthropathies
0.077 0.895 0.028
K75.4 Autoimmune hepatitis
0.000 0.897 0.103
H36.8 Other retinal disorders in diseases classified elsewhere
0.000 0.898 0.102
M06.08 Seronegative rheumatoid arthritis (Other)
0.006 0.901 0.093
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)
0.006 0.901 0.093
M06.04 Seronegative rheumatoid arthritis (Hand)
0.006 0.901 0.093
M06.03 Seronegative rheumatoid arthritis (Forearm)
0.006 0.901 0.093
M06.02 Seronegative rheumatoid arthritis (Upper arm)
0.006 0.901 0.093
K75 Other inflammatory liver diseases
0.000 0.902 0.098
M48 Other spondylopathies
0.097 0.903 0.000
E61.1 Iron deficiency
0.000 0.905 0.095
K70-K77 Diseases of liver
0.000 0.905 0.095
K52.2 Allergic and dietetic gastro-enteritis and colitis
0.094 0.906 0.000
K74 Fibrosis and cirrhosis of liver
0.000 0.906 0.094
H22 Disorders of iris and ciliary body in diseases classified elsewhere
0.093 0.907 0.000
M06.01 Seronegative rheumatoid arthritis (Shoulder region)
0.007 0.909 0.084
M07.6 Other enteropathic arthropathies
0.083 0.909 0.008
H21.8 Other specified disorders of iris and ciliary body
0.091 0.909 0.000
M07.5 Arthropathy in ulcerative colitis
0.082 0.910 0.008
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.082 0.910 0.008
M07.2 Psoriatic spondylitis
0.082 0.910 0.008
M07.1 Arthritis mutilans
0.082 0.910 0.008
M07.0 Distal interphalangeal psoriatic arthropathy
0.082 0.910 0.008
K72 Hepatic failure, not elsewhere classified
0.000 0.910 0.090
M48.5 Collapsed vertebra, not elsewhere classified
0.087 0.913 0.000
K74.6 Other and unspecified cirrhosis of liver
0.000 0.913 0.087
K73 Chronic hepatitis, not elsewhere classified
0.000 0.914 0.086
K72.9 Hepatic failure, unspecified
0.000 0.914 0.086
K74.3 Primary biliary cirrhosis
0.000 0.915 0.085
M49 Spondylopathies in diseases classified elsewhere
0.085 0.915 0.000
K75.8 Other specified inflammatory liver diseases
0.000 0.915 0.085
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)
0.007 0.916 0.077
E04.8 Other specified non-toxic goitre
0.000 0.917 0.083
H21.2 Degeneration of iris and ciliary body
0.082 0.917 0.000
M00 Pyogenic arthritis
0.082 0.918 0.000
M00-M03 Infectious arthropathies
0.082 0.918 0.000
H21.4 Pupillary membranes
0.081 0.918 0.000
H21.3 Cyst of iris, ciliary body and anterior chamber
0.081 0.918 0.000
M00.9 Pyogenic arthritis, unspecified
0.081 0.919 0.000
E61.2 Magnesium deficiency
0.001 0.920 0.080
H19 Disorders of sclera and cornea in diseases classified elsewhere
0.080 0.920 0.000
M02 Reactive arthropathies
0.079 0.921 0.000
H30-H36 Disorders of choroid and retina
0.000 0.921 0.079
K73.2 Chronic active hepatitis, not elsewhere classified
0.000 0.921 0.079
E53.1 Pyridoxine deficiency
0.000 0.922 0.078
E53.0 Riboflavin deficiency
0.000 0.922 0.078
M48.56 Collapsed vertebra, not elsewhere classified (Lumbar region)
0.078 0.922 0.000
K74.5 Biliary cirrhosis, unspecified
0.000 0.922 0.078
H17 Corneal scars and opacities
0.077 0.922 0.000
H16 Keratitis
0.077 0.923 0.000
K75.3 Granulomatous hepatitis, not elsewhere classified
0.000 0.923 0.077
M08 Juvenile arthritis
0.057 0.923 0.019
K50.8 Other Crohn's disease
0.076 0.924 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.056 0.924 0.020
K71 Toxic liver disease
0.000 0.925 0.075
M12 Other specific arthropathies
0.056 0.925 0.019
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.075 0.925 0.000
M05 Seropositive rheumatoid arthritis
0.051 0.926 0.023
H21.9 Disorder of iris and ciliary body, unspecified
0.073 0.927 0.000
M48.9 Spondylopathy, unspecified
0.073 0.927 0.000
H22.1 Iridocyclitis in other diseases classified elsewhere
0.073 0.927 0.000
K74.0 Hepatic fibrosis
0.000 0.927 0.073
M11 Other crystal arthropathies
0.058 0.928 0.014

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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