TreeWAS – Variant ID: rs508487

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E78.0 Pure hypercholesterolaemia	0.999	0.001	0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias	0.954	0.046	0.000
E78.5 Hyperlipidaemia, unspecified	0.938	0.062	0.000
E78.2 Mixed hyperlipidaemia	0.789	0.211	0.000
E78.1 Pure hyperglyceridaemia	0.749	0.251	0.000
E78.4 Other hyperlipidaemia	0.713	0.287	0.000
E78.6 Lipoprotein deficiency	0.684	0.316	0.000
E78.3 Hyperchylomicronaemia	0.684	0.316	0.000
E78.9 Disorder of lipoprotein metabolism, unspecified	0.660	0.340	0.000
E78.8 Other disorders of lipoprotein metabolism	0.588	0.412	0.000
E70-E90 Metabolic disorders	0.043	0.957	0.000
E80 Disorders of porphyrin and bilirubin metabolism	0.037	0.963	0.000
E80.4 Gilbert's syndrome	0.033	0.967	0.000
E88 Other metabolic disorders	0.033	0.967	0.000
E85 Amyloidosis	0.032	0.968	0.000
E74 Other disorders of carbohydrate metabolism	0.031	0.969	0.000
E84 Cystic fibrosis	0.031	0.969	0.000
E79 Disorders of purine and pyrimidine metabolism	0.031	0.969	0.000
E77 Disorders of glycoprotein metabolism	0.031	0.969	0.000
E76 Disorders of glycosaminoglycan metabolism	0.031	0.969	0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.031	0.969	0.000
E72 Other disorders of amino-acid metabolism	0.031	0.969	0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.031	0.969	0.000
E70 Disorders of aromatic amino-acid metabolism	0.031	0.969	0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.031	0.969	0.000
E73 Lactose intolerance	0.028	0.971	0.000
E80.7 Disorder of bilirubin metabolism, unspecified	0.027	0.973	0.000
E80.6 Other disorders of bilirubin metabolism	0.027	0.973	0.000
E80.5 Crigler-Najjar syndrome	0.027	0.973	0.000
E80.3 Defects of catalase and peroxydase	0.027	0.973	0.000
E80.2 Other porphyria	0.027	0.973	0.000
E80.1 Porphyria cutanea tarda	0.027	0.973	0.000
E80.0 Hereditary erythropoietic porphyria	0.027	0.973	0.000
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified	0.025	0.975	0.000
E85.4 Organ-limited amyloidosis	0.024	0.976	0.000
M16.1 Other primary coxarthrosis	0.000	0.976	0.024
E88.9 Metabolic disorder, unspecified	0.024	0.976	0.000
E88.8 Other specified metabolic disorders	0.024	0.976	0.000
E88.3 Tumour lysis syndrome	0.024	0.976	0.000
E88.2 Lipomatosis, not elsewhere classified	0.024	0.976	0.000
E88.1 Lipodystrophy, not elsewhere classified	0.024	0.976	0.000
E85.9 Amyloidosis, unspecified	0.023	0.977	0.000
E85.8 Other amyloidosis	0.023	0.977	0.000
E85.3 Secondary systemic amyloidosis	0.023	0.977	0.000
E85.2 Heredofamilial amyloidosis, unspecified	0.023	0.977	0.000
E85.1 Neuropathic heredofamilial amyloidosis	0.023	0.977	0.000
E85.0 Nonneuropathic heredofamilial amyloidosis	0.023	0.977	0.000
E74.3 Other disorders of intestinal carbohydrate absorption	0.022	0.977	0.000
E74.9 Disorder of carbohydrate metabolism, unspecified	0.022	0.977	0.000
E74.8 Other specified disorders of carbohydrate metabolism	0.022	0.977	0.000
E74.4 Disorders of pyruvate metabolism and gluconeogenesis	0.022	0.977	0.000
E74.2 Disorders of galactose metabolism	0.022	0.977	0.000
E74.1 Disorders of fructose metabolism	0.022	0.977	0.000
E74.0 Glycogen storage disease	0.022	0.977	0.000
E70.9 Disorder of aromatic amino-acid metabolism, unspecified	0.022	0.977	0.000
E70.8 Other disorders of aromatic amino-acid metabolism	0.022	0.977	0.000
E70.3 Albinism	0.022	0.977	0.000
E70.2 Disorders of tyrosine metabolism	0.022	0.977	0.000
E70.1 Other hyperphenylalaninaemias	0.022	0.977	0.000
E70.0 Classical phenylketonuria	0.022	0.977	0.000
E71.3 Disorders of fatty-acid metabolism	0.022	0.977	0.000
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified	0.022	0.977	0.000
E71.1 Other disorders of branched-chain amino-acid metabolism	0.022	0.977	0.000
E71.0 Maple-syrup-urine disease	0.022	0.977	0.000
E72.9 Disorder of amino-acid metabolism, unspecified	0.022	0.977	0.000
E72.8 Other specified disorders of amino-acid metabolism	0.022	0.977	0.000
E72.5 Disorders of glycine metabolism	0.022	0.977	0.000
E72.4 Disorders of ornithine metabolism	0.022	0.977	0.000
E72.3 Disorders of lysine and hydroxylysine metabolism	0.022	0.977	0.000
E72.2 Disorders of urea cycle metabolism	0.022	0.977	0.000
E72.1 Disorders of sulphur-bearing amino-acid metabolism	0.022	0.977	0.000
E72.0 Disorders of amino-acid transport	0.022	0.977	0.000
E75.6 Lipid storage disorder, unspecified	0.022	0.977	0.000
E75.5 Other lipid storage disorders	0.022	0.977	0.000
E75.4 Neuronal ceroid lipofuscinosis	0.022	0.977	0.000
E75.3 Sphingolipidosis, unspecified	0.022	0.977	0.000
E75.2 Other sphingolipidosis	0.022	0.977	0.000
E75.1 Other gangliosidosis	0.022	0.977	0.000
E75.0 GM2 gangliosidosis	0.022	0.977	0.000
E76.9 Disorder of glucosaminoglycan metabolism, unspecified	0.022	0.977	0.000
E76.8 Other disorders of glucosaminoglycan metabolism	0.022	0.977	0.000
E76.3 Mucopolysaccharidosis, unspecified	0.022	0.977	0.000
E76.2 Other mucopolysaccharidoses	0.022	0.977	0.000
E76.1 Mucopolysaccharidosis, type II	0.022	0.977	0.000
E76.0 Mucopolysaccharidosis, type I	0.022	0.977	0.000
E77.9 Disorder of glycoprotein metabolism, unspecified	0.022	0.977	0.000
E77.8 Other disorders of glycoprotein metabolism	0.022	0.977	0.000
E77.1 Defects in glycoprotein degradation	0.022	0.977	0.000
E77.0 Defects in posttranslational modification of lysosomal enzymes	0.022	0.977	0.000
E79.9 Disorder of purine and pyrimidine metabolism, unspecified	0.022	0.977	0.000
E79.8 Other disorders of purine and pyrimidine metabolism	0.022	0.977	0.000
E79.1 Lesch-Nyhan syndrome	0.022	0.977	0.000
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease	0.022	0.977	0.000
E84.9 Cystic fibrosis, unspecified	0.022	0.977	0.000
E84.8 Cystic fibrosis with other manifestations	0.022	0.977	0.000
E84.1 Cystic fibrosis with intestinal manifestations	0.022	0.977	0.000
E84.0 Cystic fibrosis with pulmonary manifestations	0.022	0.977	0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.021	0.979	0.000
E73.8 Other lactose intolerance	0.020	0.979	0.000
E73.1 Secondary lactase deficiency	0.020	0.979	0.000
E73.0 Congenital lactase deficiency	0.020	0.979	0.000
H26.9 Cataract, unspecified	0.020	0.980	0.000
E73.9 Lactose intolerance, unspecified	0.018	0.982	0.000
E86 Volume depletion	0.018	0.982	0.000
E89.2 Postprocedural hypoparathyroidism	0.016	0.983	0.000
E89.9 Postprocedural endocrine and metabolic disorder, unspecified	0.015	0.985	0.000
E89.8 Other postprocedural endocrine and metabolic disorders	0.015	0.985	0.000
E89.6 Postprocedural adrenocortical(-medullary) hypofunction	0.015	0.985	0.000
E89.5 Postprocedural testicular hypofunction	0.015	0.985	0.000
E89.4 Postprocedural ovarian failure	0.015	0.985	0.000
E89.1 Postprocedural hypoinsulinaemia	0.015	0.985	0.000
M16 Coxarthrosis [arthrosis of hip]	0.000	0.985	0.015
E89.3 Postprocedural hypopituitarism	0.013	0.986	0.000
M16.0 Primary coxarthrosis, bilateral	0.000	0.987	0.013
E83 Disorders of mineral metabolism	0.012	0.988	0.000
Z45.8 Adjustment and management of other implanted devices	0.012	0.988	0.000
M16.3 Other dysplastic coxarthrosis	0.000	0.989	0.011
M16.9 Coxarthrosis, unspecified	0.000	0.989	0.011
M16.6 Other secondary coxarthrosis, bilateral	0.000	0.989	0.011
M16.5 Other posttraumatic coxarthrosis	0.000	0.989	0.011
M16.4 Posttraumatic coxarthrosis, bilateral	0.000	0.989	0.011
M16.2 Coxarthrosis resulting from dysplasia, bilateral	0.000	0.989	0.011
M16.7 Other secondary coxarthrosis	0.000	0.989	0.011
E83.3 Disorders of phosphorus metabolism	0.010	0.990	0.000
I10 Essential (primary) hypertension	0.010	0.990	0.000
I71.9 Aortic aneurysm of unspecified site, without mention of rupture	0.009	0.991	0.000
E83.9 Disorder of mineral metabolism, unspecified	0.009	0.991	0.000
E83.8 Other disorders of mineral metabolism	0.009	0.991	0.000
E83.2 Disorders of zinc metabolism	0.009	0.991	0.000
E83.0 Disorders of copper metabolism	0.009	0.991	0.000
I71 Aortic aneurysm and dissection	0.009	0.991	0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture	0.008	0.991	0.000
H26 Other cataract	0.008	0.992	0.000
H02.9 Disorder of eyelid, unspecified	0.007	0.993	0.000
I70-I79 Diseases of arteries, arterioles and capillaries	0.007	0.993	0.000
I74 Arterial embolism and thrombosis	0.007	0.993	0.000
H26.0 Infantile, juvenile and presenile cataract	0.007	0.993	0.000
H25.0 Senile incipient cataract	0.007	0.993	0.000
H25-H28 Disorders of lens	0.007	0.993	0.000
I72 Other aneurysm	0.007	0.993	0.000
I71.8 Aortic aneurysm of unspecified site, ruptured	0.006	0.993	0.000
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture	0.006	0.993	0.000
I71.5 Thoracoabdominal aortic aneurysm, ruptured	0.006	0.993	0.000
I71.1 Thoracic aortic aneurysm, ruptured	0.006	0.993	0.000
I71.0 Dissection of aorta [any part]	0.006	0.994	0.000
H26.3 Drug-induced cataract	0.006	0.994	0.000
I70 Atherosclerosis	0.006	0.994	0.000
E83.4 Disorders of magnesium metabolism	0.006	0.994	0.000
H25 Senile cataract	0.006	0.994	0.000
I71.3 Abdominal aortic aneurysm, ruptured	0.006	0.994	0.000
I74.0 Embolism and thrombosis of abdominal aorta	0.006	0.994	0.000
I74.2 Embolism and thrombosis of arteries of the upper extremities	0.006	0.994	0.000
I71.2 Thoracic aortic aneurysm, without mention of rupture	0.006	0.994	0.000
I72.8 Aneurysm of other specified arteries	0.006	0.994	0.000
O68.1 Labour and delivery complicated by meconium in amniotic fluid	0.000	0.994	0.006
H27 Other disorders of lens	0.006	0.994	0.000
E89.0 Postprocedural hypothyroidism	0.006	0.994	0.000
H02.3 Blepharochalasis	0.006	0.994	0.000
H02 Other disorders of eyelid	0.006	0.994	0.000
I72.0 Aneurysm of carotid artery	0.006	0.994	0.000
I74.8 Embolism and thrombosis of other arteries	0.006	0.994	0.000
I70.2 Atherosclerosis of arteries of the extremities	0.006	0.994	0.000
I74.9 Embolism and thrombosis of unspecified artery	0.005	0.994	0.000
N39.4 Other specified urinary incontinence	0.000	0.994	0.006
S30.8 Other superficial injuries of abdomen, lower back and pelvis	0.005	0.995	0.000
S32.50 Fracture of pubis (closed)	0.005	0.995	0.000
S30 Superficial injury of abdomen, lower back and pelvis	0.005	0.995	0.000
I72.4 Aneurysm of artery of lower extremity	0.005	0.995	0.000
I74.5 Embolism and thrombosis of iliac artery	0.005	0.995	0.000
H02.5 Other disorders affecting eyelid function	0.005	0.995	0.000
H02.1 Ectropion of eyelid	0.005	0.995	0.000
I74.4 Embolism and thrombosis of arteries of extremities, unspecified	0.005	0.995	0.000
I74.1 Embolism and thrombosis of other and unspecified parts of aorta	0.005	0.995	0.000
I34.0 Mitral (valve) insufficiency	0.005	0.995	0.000
I77 Other disorders of arteries and arterioles	0.005	0.995	0.000
H27.1 Dislocation of lens	0.005	0.995	0.000
I70.0 Atherosclerosis of aorta	0.005	0.995	0.000
I78 Diseases of capillaries	0.005	0.995	0.000
H25.1 Senile nuclear cataract	0.005	0.995	0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities	0.005	0.995	0.000
H28 Cataract and other disorders of lens in diseases classified elsewhere	0.005	0.995	0.000
I70.20 Atherosclerosis of arteries of extremities (without gangrene)	0.005	0.995	0.000
H26.1 Traumatic cataract	0.005	0.995	0.000
I72.9 Aneurysm of unspecified site	0.005	0.995	0.000
I72.6 Aneurysm and dissection of vertebral artery	0.005	0.995	0.000
I72.5 Aneurysm and dissection of other precerebral arteries	0.005	0.995	0.000
I72.2 Aneurysm of renal artery	0.005	0.995	0.000
I72.1 Aneurysm of artery of upper extremity	0.005	0.995	0.000
E83.5 Disorders of calcium metabolism	0.005	0.995	0.000
H02.0 Entropion and trichiasis of eyelid	0.005	0.995	0.000
H26.2 Complicated cataract	0.005	0.995	0.000
H26.4 After-cataract	0.005	0.995	0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.005	0.995	0.000
S30.9 Superficial injury of abdomen, lower back and pelvis, part unspecified	0.005	0.995	0.000
I70.9 Generalised and unspecified atherosclerosis	0.005	0.995	0.000
I70.8 Atherosclerosis of other arteries	0.005	0.995	0.000
I70.1 Atherosclerosis of renal artery	0.005	0.995	0.000
H25.2 Senile cataract, morgagnian type	0.005	0.995	0.000
H26.8 Other specified cataract	0.005	0.995	0.000
S30.0 Contusion of lower back and pelvis	0.005	0.995	0.000
S30.1 Contusion of abdominal wall	0.005	0.995	0.000
H27.8 Other specified disorders of lens	0.005	0.995	0.000
I34.1 Mitral (valve) prolapse	0.005	0.995	0.000
I72.3 Aneurysm of iliac artery	0.004	0.995	0.000
I77.1 Stricture of artery	0.005	0.995	0.000
I78.0 Hereditary haemorrhagic telangiectasia	0.004	0.995	0.000
H27.9 Disorder of lens, unspecified	0.004	0.995	0.000
I77.0 Arteriovenous fistula, acquired	0.004	0.996	0.000
S32.5 Fracture of pubis	0.004	0.996	0.000
E83.1 Disorders of iron metabolism	0.004	0.996	0.000
I70.00 Atherosclerosis of aorta (without gangrene)	0.004	0.996	0.000
H02.7 Other degenerative disorders of eyelid and periocular area	0.004	0.996	0.000
H02.2 Lagophthalmos	0.004	0.996	0.000
H27.0 Aphakia	0.004	0.996	0.000
I70.21 Atherosclerosis of arteries of extremities (with gangrene)	0.004	0.996	0.000
O47.1 False labour at or after 37 completed weeks of gestation	0.004	0.996	0.000
O68.9 Labour and delivery complicated by foetal stress, unspecified	0.000	0.996	0.004
I34 Nonrheumatic mitral valve disorders	0.004	0.996	0.000
I77.8 Other specified disorders of arteries and arterioles	0.004	0.996	0.000
I78.8 Other diseases of capillaries	0.004	0.996	0.000
S30.7 Multiple superficial injuries of abdomen, lower back and pelvis	0.004	0.996	0.000
H25.9 Senile cataract, unspecified	0.004	0.996	0.000
S30.2 Contusion of external genital organs	0.004	0.996	0.000
I77.5 Necrosis of artery	0.004	0.996	0.000
I77.4 Coeliac artery compression syndrome	0.004	0.996	0.000
I77.3 Arterial fibromuscular dysplasia	0.004	0.996	0.000
I77.2 Rupture of artery	0.004	0.996	0.000
I78.9 Disease of capillaries, unspecified	0.004	0.996	0.000
I70.01 Atherosclerosis of aorta (with gangrene)	0.004	0.996	0.000
H28.8 Other disorders of lens in diseases classified elsewhere	0.004	0.996	0.000
H28.2 Cataract in other diseases classified elsewhere	0.004	0.996	0.000
H28.1 Cataract in other endocrine, nutritional and metabolic diseases	0.004	0.996	0.000
H28.0 Diabetic cataract	0.004	0.996	0.000
H02.6 Xanthelasma of eyelid	0.004	0.996	0.000
H33.0 Retinal detachment with retinal break	0.004	0.996	0.000
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.004	0.996	0.000
I79.1 Aortitis in diseases classified elsewhere	0.004	0.996	0.000
I79.0 Aneurysm of aorta in diseases classified elsewhere	0.004	0.996	0.000
S82.10 Fracture of upper end of tibia (closed)	0.004	0.996	0.000
I70.11 Atherosclerosis of renal artery (with gangrene)	0.003	0.996	0.000
I70.10 Atherosclerosis of renal artery (without gangrene)	0.003	0.996	0.000
I70.81 Atherosclerosis of other arteries (with gangrene)	0.003	0.996	0.000
I70.80 Atherosclerosis of other arteries (without gangrene)	0.003	0.996	0.000
I70.91 Generalized and unspecified atherosclerosis (with gangrene)	0.003	0.996	0.000
I70.90 Generalized and unspecified atherosclerosis (without gangrene)	0.003	0.996	0.000
S32 Fracture of lumbar spine and pelvis	0.004	0.996	0.000
I34.2 Nonrheumatic mitral (valve) stenosis	0.004	0.996	0.000
T78.3 Angioneurotic oedema	0.000	0.996	0.004
O68 Labour and delivery complicated by foetal stress [distress]	0.000	0.996	0.004
O68.2 Labour and delivery complicated by foetal heart rate anomaly with meconium in amniotic fluid	0.000	0.997	0.003
S32.51 Fracture of pubis (open)	0.003	0.997	0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.003	0.997	0.000
I79.2 Peripheral angiopathy in diseases classified elsewhere	0.003	0.997	0.000
T78.2 Anaphylactic shock, unspecified	0.000	0.997	0.003
I10-I15 Hypertensive diseases	0.003	0.997	0.000
T93.3 Sequelae of dislocation, sprain and strain of lower limb	0.003	0.997	0.000
S32.8 Fracture of other and unspecified parts of lumbar spine and pelvis	0.003	0.997	0.000
I34.8 Other nonrheumatic mitral valve disorders	0.003	0.997	0.000
T78 Adverse effects, not elsewhere classified	0.000	0.997	0.003
O20.9 Haemorrhage in early pregnancy, unspecified	0.003	0.997	0.000
S32.1 Fracture of sacrum	0.003	0.997	0.000
I77.9 Disorder of arteries and arterioles, unspecified	0.003	0.997	0.000
H33 Retinal detachments and breaks	0.003	0.997	0.000
S32.80 Fracture of other and unspecified parts of lumbar spine and pelvis (closed)	0.003	0.997	0.000
I34.9 Nonrheumatic mitral valve disorder, unspecified	0.003	0.997	0.000
I77.6 Arteritis, unspecified	0.003	0.997	0.000
S32.2 Fracture of coccyx	0.003	0.997	0.000
S32.7 Multiple fractures of lumbar spine and pelvis	0.003	0.997	0.000
H33.4 Traction detachment of retina	0.003	0.997	0.000
S32.10 Fracture of sacrum (closed)	0.003	0.997	0.000
S32.3 Fracture of ilium	0.003	0.997	0.000
T78.4 Allergy, unspecified	0.000	0.997	0.003
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis	0.003	0.997	0.000
S37 Injury of urinary and pelvic organs	0.003	0.997	0.000
S36 Injury of intra-abdominal organs	0.003	0.997	0.000
S35 Injury of blood vessels at abdomen, lower back and pelvis level	0.003	0.997	0.000
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level	0.003	0.997	0.000
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis	0.003	0.997	0.000
S31 Open wound of abdomen, lower back and pelvis	0.003	0.997	0.000
T78.1 Other adverse food reactions, not elsewhere classified	0.000	0.997	0.003
K56.5 Intestinal adhesions [bands] with obstruction	0.003	0.997	0.000
E87 Other disorders of fluid, electrolyte and acid-base balance	0.003	0.997	0.000
H25.8 Other senile cataract	0.003	0.997	0.000
T78.0 Anaphylactic shock due to adverse food reaction	0.000	0.997	0.003
I15 Secondary hypertension	0.003	0.997	0.000
I13 Hypertensive heart and renal disease	0.003	0.997	0.000
I78.1 Naevus, nonneoplastic	0.003	0.997	0.000
S32.81 Fracture of other and unspecified parts of lumbar spine and pelvis (open)	0.002	0.997	0.000
H33.5 Other retinal detachments	0.003	0.997	0.000
O20 Haemorrhage in early pregnancy	0.003	0.997	0.000
T78.9 Adverse effect, unspecified	0.000	0.997	0.002
T78.8 Other adverse effects, not elsewhere classified	0.000	0.997	0.002
O42.0 Premature rupture of membranes, onset of labour within 24 hours	0.003	0.997	0.000
S32.11 Fracture of sacrum (open)	0.002	0.997	0.000
J92.0 Pleural plaque with presence of asbestos	0.000	0.997	0.003
H33.1 Retinoschisis and retinal cysts	0.002	0.997	0.000
H49.0 Third [oculomotor] nerve palsy	0.002	0.997	0.000
I11 Hypertensive heart disease	0.002	0.997	0.000
H30-H36 Disorders of choroid and retina	0.003	0.997	0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit	0.002	0.997	0.000
O68.3 Labour and delivery complicated by biochemical evidence of foetal stress	0.000	0.997	0.002
S32.0 Fracture of lumbar vertebra	0.002	0.997	0.000
H21.8 Other specified disorders of iris and ciliary body	0.002	0.998	0.000
S32.4 Fracture of acetabulum	0.002	0.998	0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis	0.002	0.998	0.000
M81.99 Osteoporosis, unspecified (Site unspecified)	0.002	0.998	0.000
Chapter VII Diseases of the eye and adnexa	0.002	0.998	0.000
S32.21 Fracture of coccyx (open)	0.002	0.998	0.000
S32.20 Fracture of coccyx (closed)	0.002	0.998	0.000
H34 Retinal vascular occlusions	0.002	0.998	0.000
S32.71 Multiple fractures of lumbar spine and pelvis (open)	0.002	0.998	0.000
S92.00 Fracture of calcaneus (closed)	0.002	0.998	0.000
O20.0 Threatened abortion	0.002	0.998	0.000
M19.91 Arthrosis, unspecified (Shoulder region)	0.002	0.998	0.000
H18.5 Hereditary corneal dystrophies	0.002	0.998	0.000
S32.70 Multiple fractures of lumbar spine and pelvis (closed)	0.002	0.998	0.000
S32.31 Fracture of ilium (open)	0.002	0.998	0.000
O26.8 Other specified pregnancy-related conditions	0.002	0.998	0.000
Z45 Adjustment and management of implanted device	0.002	0.998	0.000
M81.9 Osteoporosis, unspecified	0.002	0.998	0.000
H34.8 Other retinal vascular occlusions	0.002	0.998	0.000
H49 Paralytic strabismus	0.002	0.998	0.000
I60.9 Subarachnoid haemorrhage, unspecified	0.000	0.998	0.002
S31.8 Open wound of other and unspecified parts of abdomen	0.002	0.998	0.000
S31.7 Multiple open wounds of abdomen, lower back and pelvis	0.002	0.998	0.000
S31.5 Open wound of other and unspecified external genital organs	0.002	0.998	0.000
S31.4 Open wound of vagina and vulva	0.002	0.998	0.000
S31.3 Open wound of scrotum and testes	0.002	0.998	0.000
S31.2 Open wound of penis	0.002	0.998	0.000
S31.1 Open wound of abdominal wall	0.002	0.998	0.000
S31.0 Open wound of lower back and pelvis	0.002	0.998	0.000
S33.7 Sprain and strain of other and unspecified parts of lumbar spine and pelvis	0.002	0.998	0.000
S33.6 Sprain and strain of sacro-iliac joint	0.002	0.998	0.000
S33.5 Sprain and strain of lumbar spine	0.002	0.998	0.000
S33.4 Traumatic rupture of symphysis pubis	0.002	0.998	0.000
S33.3 Dislocation of other and unspecified parts of lumbar spine and pelvis	0.002	0.998	0.000
S33.2 Dislocation of sacro-iliac and sacrococcygeal joint	0.002	0.998	0.000
S33.1 Dislocation of lumbar vertebra	0.002	0.998	0.000
S33.0 Traumatic rupture of lumbar intervertebral disk	0.002	0.998	0.000
S34.8 Injury of other and unspecified nerves at abdomen, lower back and pelvis level	0.002	0.998	0.000
S34.6 Injury of peripheral nerve(s) of abdomen, lower back and pelvis	0.002	0.998	0.000
S34.5 Injury of lumbar, sacral and pelvic sympathetic nerves	0.002	0.998	0.000
S34.4 Injury of lumbosacral plexus	0.002	0.998	0.000
S34.3 Injury of cauda equina	0.002	0.998	0.000
S34.2 Injury of nerve root of lumbar and sacral spine	0.002	0.998	0.000
S34.1 Other injury of lumbar spinal cord	0.002	0.998	0.000
S34.0 Concussion and oedema of lumbar spinal cord	0.002	0.998	0.000
S35.9 Injury of unspecified blood vessel at abdomen, lower back and pelvis level	0.002	0.998	0.000
S35.8 Injury of other blood vessels at abdomen, lower back and pelvis level	0.002	0.998	0.000
S35.7 Injury of multiple blood vessels at abdomen, lower back and pelvis level	0.002	0.998	0.000
S35.5 Injury of iliac blood vessels	0.002	0.998	0.000
S35.4 Injury of renal blood vessels	0.002	0.998	0.000
S35.3 Injury of portal or splenic vein	0.002	0.998	0.000
S35.2 Injury of coeliac or mesenteric artery	0.002	0.998	0.000
S35.1 Injury of inferior vena cava	0.002	0.998	0.000
S35.0 Injury of abdominal aorta	0.002	0.998	0.000
S36.9 Injury of unspecified intra-abdominal organ	0.002	0.998	0.000
S36.8 Injury of other intra-abdominal organs	0.002	0.998	0.000
S36.7 Injury of multiple intra-abdominal organs	0.002	0.998	0.000
S36.6 Injury of rectum	0.002	0.998	0.000
S36.5 Injury of colon	0.002	0.998	0.000
S36.4 Injury of small intestine	0.002	0.998	0.000
S36.3 Injury of stomach	0.002	0.998	0.000
S36.2 Injury of pancreas	0.002	0.998	0.000
S36.1 Injury of liver or gallbladder	0.002	0.998	0.000
S36.0 Injury of spleen	0.002	0.998	0.000
S37.9 Injury of unspecified pelvic organ	0.002	0.998	0.000
S37.8 Injury of other pelvic organs	0.002	0.998	0.000
S37.7 Injury of multiple pelvic organs	0.002	0.998	0.000
S37.6 Injury of uterus	0.002	0.998	0.000
S37.5 Injury of Fallopian tube	0.002	0.998	0.000
S37.4 Injury of ovary	0.002	0.998	0.000
S37.3 Injury of urethra	0.002	0.998	0.000
S37.2 Injury of bladder	0.002	0.998	0.000
S37.1 Injury of ureter	0.002	0.998	0.000
S37.0 Injury of kidney	0.002	0.998	0.000
S38.3 Traumatic amputation of other and unspecified parts of abdomen, lower back and pelvis	0.002	0.998	0.000
S38.2 Traumatic amputation of external genital organs	0.002	0.998	0.000
S38.1 Crushing injury of other and unspecified parts of abdomen, lower back and pelvis	0.002	0.998	0.000
S38.0 Crushing injury of external genital organs	0.002	0.998	0.000
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere	0.002	0.998	0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction	0.002	0.998	0.000
S39.8 Other specified injuries of abdomen, lower back and pelvis	0.002	0.998	0.000
H05 Disorders of orbit	0.002	0.998	0.000
H30 Chorioretinal inflammation	0.002	0.998	0.000
E87.4 Mixed disorder of acid-base balance	0.002	0.998	0.000
N39.3 Stress incontinence	0.000	0.998	0.002
H21 Other disorders of iris and ciliary body	0.002	0.998	0.000
I13.9 Hypertensive heart and renal disease, unspecified	0.002	0.998	0.000
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure	0.002	0.998	0.000
I13.1 Hypertensive heart and renal disease with renal failure	0.002	0.998	0.000
I13.0 Hypertensive heart and renal disease with (congestive) heart failure	0.002	0.998	0.000
I15.9 Seconday hypertension, unspecified	0.002	0.998	0.000
I15.8 Other secondary hypertension	0.002	0.998	0.000
I15.2 Hypertension secondary to endocrine disorders	0.002	0.998	0.000
I15.1 Hypertension secondary to other renal disorders	0.002	0.998	0.000
I15.0 Renovascular hypertension	0.002	0.998	0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.002	0.998	0.000
H10-H13 Disorders of conjunctiva	0.002	0.998	0.000
H18 Other disorders of cornea	0.002	0.998	0.000
H52.7 Disorder of refraction, unspecified	0.002	0.998	0.000
H52.1 Myopia	0.002	0.998	0.000
O20.8 Other haemorrhage in early pregnancy	0.002	0.998	0.000
O68.8 Labour and delivery complicated by other evidence of foetal stress	0.000	0.998	0.002
Chapter IV Endocrine, nutritional and metabolic diseases	0.002	0.998	0.000
S32.30 Fracture of ilium (closed)	0.002	0.998	0.000
M81.97 Osteoporosis, unspecified (Ankle and foot)	0.002	0.998	0.000
M81.90 Osteoporosis, unspecified (Multiple sites)	0.002	0.998	0.000
Z08.7 Follow-up examination after combined treatment for malignant neoplasm	0.002	0.998	0.000
H52 Disorders of refraction and accommodation	0.002	0.998	0.000
E87.3 Alkalosis	0.002	0.998	0.000
H02.8 Other specified disorders of eyelid	0.002	0.998	0.000
I11.0 Hypertensive heart disease with (congestive) heart failure	0.002	0.998	0.000
H32 Chorioretinal disorders in diseases classified elsewhere	0.002	0.998	0.000
H31 Other disorders of choroid	0.002	0.998	0.000
I73 Other peripheral vascular diseases	0.002	0.998	0.000
M51.2 Other specified intervertebral disk displacement	0.000	0.998	0.002
H03 Disorders of eyelid in diseases classified elsewhere	0.002	0.998	0.000
S32.01 Fracture of lumbar vertebra (open)	0.002	0.998	0.000
H06.2 Dysthyroid exophthalmos	0.002	0.998	0.000
S32.41 Fracture of acetabulum (open)	0.002	0.998	0.000
H34.1 Central retinal artery occlusion	0.002	0.998	0.000
S39.7 Other multiple injuries of abdomen, lower back and pelvis	0.002	0.998	0.000
S39.6 Injury of intra-abdominal organ(s) with pelvic organ(s)	0.002	0.998	0.000
S39.0 Injury of muscle and tendon of abdomen, lower back and pelvis	0.002	0.998	0.000
S06.60 Traumatic subarachnoid haemorrhage (without open intracranial wound)	0.002	0.998	0.000
E87.7 Fluid overload	0.002	0.998	0.000
S82.1 Fracture of upper end of tibia	0.002	0.998	0.000
H05.0 Acute inflammation of orbit	0.002	0.998	0.000
H30.9 Chorioretinal inflammation, unspecified	0.002	0.998	0.000
C45.0 Mesothelioma of pleura	0.000	0.998	0.002
H11 Other disorders of conjunctiva	0.002	0.998	0.000
H11.8 Other specified disorders of conjunctiva	0.002	0.998	0.000
H34.9 Retinal vascular occlusion, unspecified	0.002	0.998	0.000
H34.0 Transient retinal artery occlusion	0.002	0.998	0.000
Z08.2 Follow-up examination after chemotherapy for malignant neoplasm	0.002	0.998	0.000
M81.95 Osteoporosis, unspecified (Pelvic region and thigh)	0.002	0.998	0.000
H34.2 Other retinal artery occlusions	0.002	0.998	0.000
M81.98 Osteoporosis, unspecified (Other)	0.002	0.998	0.000
Z45.1 Adjustment and management of infusion pump	0.002	0.998	0.000
I12 Hypertensive renal disease	0.002	0.998	0.000
O26 Maternal care for other conditions predominantly related to pregnancy	0.002	0.998	0.000
O20-O29 Other maternal disorders predominantly related to pregnancy	0.002	0.998	0.000
I11.9 Hypertensive heart disease without (congestive) heart failure	0.002	0.998	0.000
Z45.9 Adjustment and management of unspecified implanted device	0.002	0.998	0.000
Z45.3 Adjustment and management of implanted hearing device	0.002	0.998	0.000
M81.96 Osteoporosis, unspecified (Lower leg)	0.002	0.998	0.000
M81.94 Osteoporosis, unspecified (Hand)	0.002	0.998	0.000
M81.93 Osteoporosis, unspecified (Forearm)	0.002	0.998	0.000
M81.92 Osteoporosis, unspecified (Upper arm)	0.002	0.998	0.000
M81.91 Osteoporosis, unspecified (Shoulder region)	0.002	0.998	0.000
H33.2 Serous retinal detachment	0.002	0.998	0.000
W07.0 Home	0.002	0.998	0.000
S36.01 Injury of spleen (with open wound into cavity)	0.002	0.998	0.000
S36.00 Injury of spleen (without open wound into cavity)	0.002	0.998	0.000
S36.11 Injury of liver or gallbladder (with open wound into cavity)	0.002	0.998	0.000
S36.10 Injury of liver or gallbladder (without open wound into cavity)	0.002	0.998	0.000
S36.21 Injury of pancreas (with open wound into cavity)	0.002	0.998	0.000
S36.20 Injury of pancreas (without open wound into cavity)	0.002	0.998	0.000
S36.31 Injury of stomach (with open wound into cavity)	0.002	0.998	0.000
S36.30 Injury of stomach (without open wound into cavity)	0.002	0.998	0.000
S36.41 Injury of small intestine (with open wound into cavity)	0.002	0.998	0.000
S36.40 Injury of small intestine (without open wound into cavity)	0.002	0.998	0.000
S36.51 Injury of colon (with open wound into cavity)	0.002	0.998	0.000
S36.50 Injury of colon (without open wound into cavity)	0.002	0.998	0.000
S36.61 Injury of rectum (with open wound into cavity)	0.002	0.998	0.000
S36.60 Injury of rectum (without open wound into cavity)	0.002	0.998	0.000
S36.71 Injury of multiple intra-abdominal organs (with open wound into cavity)	0.002	0.998	0.000
S36.70 Injury of multiple intra-abdominal organs (without open wound into cavity)	0.002	0.998	0.000
S36.81 Injury of other intra-abdominal organs (with open wound into cavity)	0.002	0.998	0.000
S36.80 Injury of other intra-abdominal organs (without open wound into cavity)	0.002	0.998	0.000
S36.91 Injury of unspecified intra-abdominal organ (with open wound into cavity)	0.002	0.998	0.000
S36.90 Injury of unspecified intra-abdominal organ (without open wound into cavity)	0.002	0.998	0.000
S37.01 Injury of kidney (with open wound into cavity)	0.002	0.998	0.000
S37.00 Injury of kidney (without open wound into cavity)	0.002	0.998	0.000
S37.11 Injury of ureter (with open wound into cavity)	0.002	0.998	0.000
S37.10 Injury of ureter (without open wound into cavity)	0.002	0.998	0.000
S37.21 Injury of bladder (with open wound into cavity)	0.002	0.998	0.000
S37.20 Injury of bladder (without open wound into cavity)	0.002	0.998	0.000
S37.31 Injury of urethra (with open wound into cavity)	0.002	0.998	0.000
S37.30 Injury of urethra (without open wound into cavity)	0.002	0.998	0.000
S37.41 Injury of ovary (with open wound into cavity)	0.002	0.998	0.000
S37.40 Injury of ovary (without open wound into cavity)	0.002	0.998	0.000
S37.51 Injury of fallopian tube (with open wound into cavity)	0.002	0.998	0.000
S37.50 Injury of fallopian tube (without open wound into cavity)	0.002	0.998	0.000
S37.61 Injury of uterus (with open wound into cavity)	0.002	0.998	0.000
S37.60 Injury of uterus (without open wound into cavity)	0.002	0.998	0.000
S37.71 Injury of multiple pelvic organs (with open wound into cavity)	0.002	0.998	0.000
S37.70 Injury of multiple pelvic organs (without open wound into cavity)	0.002	0.998	0.000
S37.81 Injury of other pelvic organs (with open wound into cavity)	0.002	0.998	0.000
S37.80 Injury of other pelvic organs (without open wound into cavity)	0.002	0.998	0.000
S37.91 Injury of unspecified pelvic organ (with open wound into cavity)	0.002	0.998	0.000
S37.90 Injury of unspecified pelvic organ (without open wound into cavity)	0.002	0.998	0.000
H06.3 Other disorders of orbit in diseases classified elsewhere	0.002	0.998	0.000
H06.1 Parasitic infestation of orbit in diseases classified elsewhere	0.002	0.998	0.000
H06.0 Disorders of lachrymal system in diseases classified elsewhere	0.002	0.998	0.000
H18.4 Corneal degeneration	0.002	0.998	0.000
H49.9 Paralytic strabismus, unspecified	0.002	0.998	0.000
H49.8 Other paralytic strabismus	0.002	0.998	0.000
H49.4 Progressive external ophthalmoplegia	0.002	0.998	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations