TreeWAS – Variant ID: rs5128

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
E78.0 Pure hypercholesterolaemia	1.000	0.000	0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias	0.854	0.146	0.000
E78.5 Hyperlipidaemia, unspecified	0.827	0.173	0.000
E78.2 Mixed hyperlipidaemia	0.735	0.265	0.000
I10 Essential (primary) hypertension	0.691	0.309	0.000
E78.1 Pure hyperglyceridaemia	0.629	0.371	0.000
E78.6 Lipoprotein deficiency	0.612	0.388	0.000
E78.3 Hyperchylomicronaemia	0.612	0.388	0.000
E78.8 Other disorders of lipoprotein metabolism	0.566	0.434	0.000
E78.4 Other hyperlipidaemia	0.545	0.455	0.000
E78.9 Disorder of lipoprotein metabolism, unspecified	0.477	0.523	0.000
I10-I15 Hypertensive diseases	0.144	0.856	0.000
I11 Hypertensive heart disease	0.113	0.887	0.000
I13 Hypertensive heart and renal disease	0.103	0.896	0.000
I11.9 Hypertensive heart disease without (congestive) heart failure	0.090	0.910	0.000
I11.0 Hypertensive heart disease with (congestive) heart failure	0.081	0.919	0.000
I15 Secondary hypertension	0.080	0.919	0.000
I13.9 Hypertensive heart and renal disease, unspecified	0.074	0.926	0.000
I13.2 Hypertensive heart and renal disease with both (congestive) heart failure and renal failure	0.074	0.926	0.000
I13.1 Hypertensive heart and renal disease with renal failure	0.074	0.926	0.000
I13.0 Hypertensive heart and renal disease with (congestive) heart failure	0.074	0.926	0.000
I15.9 Seconday hypertension, unspecified	0.058	0.942	0.000
I15.8 Other secondary hypertension	0.058	0.942	0.000
I15.2 Hypertension secondary to endocrine disorders	0.058	0.942	0.000
I15.0 Renovascular hypertension	0.058	0.942	0.000
I12 Hypertensive renal disease	0.050	0.950	0.000
I15.1 Hypertension secondary to other renal disorders	0.035	0.964	0.001
I12.9 Hypertensive renal disease without renal failure	0.021	0.978	0.000
M51.2 Other specified intervertebral disk displacement	0.000	0.982	0.018
I12.0 Hypertensive renal disease with renal failure	0.016	0.984	0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture	0.014	0.986	0.000
I71.9 Aortic aneurysm of unspecified site, without mention of rupture	0.014	0.986	0.000
I71 Aortic aneurysm and dissection	0.014	0.986	0.000
H83.0 Labyrinthitis	0.012	0.988	0.000
D18.0 Haemangioma, any site	0.000	0.988	0.012
I71.2 Thoracic aortic aneurysm, without mention of rupture	0.012	0.988	0.000
M16.1 Other primary coxarthrosis	0.000	0.989	0.011
R35 Polyuria	0.000	0.989	0.011
H83 Other diseases of inner ear	0.010	0.990	0.000
I71.8 Aortic aneurysm of unspecified site, ruptured	0.010	0.990	0.000
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture	0.010	0.990	0.000
I71.5 Thoracoabdominal aortic aneurysm, ruptured	0.010	0.990	0.000
I71.1 Thoracic aortic aneurysm, ruptured	0.010	0.990	0.000
I71.0 Dissection of aorta [any part]	0.010	0.990	0.000
I71.3 Abdominal aortic aneurysm, ruptured	0.009	0.991	0.000
H02.9 Disorder of eyelid, unspecified	0.009	0.991	0.000
I74 Arterial embolism and thrombosis	0.009	0.991	0.000
H83.8 Other specified diseases of inner ear	0.009	0.991	0.000
I70-I79 Diseases of arteries, arterioles and capillaries	0.009	0.991	0.000
T81.3 Disruption of operation wound, not elsewhere classified	0.000	0.991	0.009
H83.9 Disease of inner ear, unspecified	0.008	0.992	0.000
E70-E90 Metabolic disorders	0.008	0.992	0.000
I74.2 Embolism and thrombosis of arteries of the upper extremities	0.008	0.992	0.000
I74.0 Embolism and thrombosis of abdominal aorta	0.008	0.992	0.000
H83.3 Noise effects on inner ear	0.008	0.992	0.000
H83.2 Labyrinthine dysfunction	0.008	0.992	0.000
H83.1 Labyrinthine fistula	0.008	0.992	0.000
H81 Disorders of vestibular function	0.008	0.992	0.000
H80-H83 Diseases of inner ear	0.007	0.993	0.000
I74.9 Embolism and thrombosis of unspecified artery	0.007	0.993	0.000
I74.5 Embolism and thrombosis of iliac artery	0.007	0.993	0.000
I72 Other aneurysm	0.007	0.993	0.000
H81.9 Disorder of vestibular function, unspecified	0.007	0.993	0.000
Z45.8 Adjustment and management of other implanted devices	0.007	0.993	0.000
H81.0 Meniere's disease	0.007	0.993	0.000
H81.1 Benign paroxysmal vertigo	0.007	0.993	0.000
I70 Atherosclerosis	0.007	0.993	0.000
I74.4 Embolism and thrombosis of arteries of extremities, unspecified	0.006	0.993	0.000
I74.1 Embolism and thrombosis of other and unspecified parts of aorta	0.006	0.993	0.000
S32.50 Fracture of pubis (closed)	0.006	0.993	0.000
I74.8 Embolism and thrombosis of other arteries	0.006	0.994	0.000
S82.10 Fracture of upper end of tibia (closed)	0.006	0.994	0.000
E74 Other disorders of carbohydrate metabolism	0.006	0.994	0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.006	0.994	0.000
I78 Diseases of capillaries	0.006	0.994	0.000
E84 Cystic fibrosis	0.006	0.994	0.000
E79 Disorders of purine and pyrimidine metabolism	0.006	0.994	0.000
E77 Disorders of glycoprotein metabolism	0.006	0.994	0.000
E76 Disorders of glycosaminoglycan metabolism	0.006	0.994	0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.006	0.994	0.000
E72 Other disorders of amino-acid metabolism	0.006	0.994	0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.006	0.994	0.000
E70 Disorders of aromatic amino-acid metabolism	0.006	0.994	0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.006	0.994	0.000
E88 Other metabolic disorders	0.006	0.994	0.000
I72.8 Aneurysm of other specified arteries	0.006	0.994	0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities	0.006	0.994	0.000
E80 Disorders of porphyrin and bilirubin metabolism	0.006	0.994	0.000
I72.0 Aneurysm of carotid artery	0.006	0.994	0.000
H81.8 Other disorders of vestibular function	0.006	0.994	0.000
H81.4 Vertigo of central origin	0.006	0.994	0.000
H81.3 Other peripheral vertigo	0.006	0.994	0.000
H82 Vertiginous syndromes in diseases classified elsewhere	0.005	0.994	0.000
I78.0 Hereditary haemorrhagic telangiectasia	0.005	0.994	0.000
R39.1 Other difficulties with micturition	0.000	0.994	0.006
B98.0 Helicobacter pylori [H.pylori] as the cause of diseases classified to other chapters	0.000	0.995	0.005
M51 Other intervertebral disk disorders	0.000	0.995	0.005
I72.3 Aneurysm of iliac artery	0.005	0.995	0.000
I70.2 Atherosclerosis of arteries of the extremities	0.005	0.995	0.000
I72.9 Aneurysm of unspecified site	0.005	0.995	0.000
I72.6 Aneurysm and dissection of vertebral artery	0.005	0.995	0.000
I72.5 Aneurysm and dissection of other precerebral arteries	0.005	0.995	0.000
I72.2 Aneurysm of renal artery	0.005	0.995	0.000
I72.1 Aneurysm of artery of upper extremity	0.005	0.995	0.000
E85 Amyloidosis	0.005	0.995	0.000
S32.5 Fracture of pubis	0.005	0.995	0.000
E73 Lactose intolerance	0.005	0.995	0.000
I70.0 Atherosclerosis of aorta	0.005	0.995	0.000
I70.9 Generalised and unspecified atherosclerosis	0.005	0.995	0.000
I70.8 Atherosclerosis of other arteries	0.005	0.995	0.000
E74.3 Other disorders of intestinal carbohydrate absorption	0.005	0.995	0.000
S30.8 Other superficial injuries of abdomen, lower back and pelvis	0.005	0.995	0.000
I70.1 Atherosclerosis of renal artery	0.005	0.995	0.000
H80 Otosclerosis	0.005	0.995	0.000
S30 Superficial injury of abdomen, lower back and pelvis	0.005	0.995	0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.005	0.995	0.000
H81.2 Vestibular neuronitis	0.005	0.995	0.000
S30.9 Superficial injury of abdomen, lower back and pelvis, part unspecified	0.005	0.995	0.000
E74.9 Disorder of carbohydrate metabolism, unspecified	0.005	0.995	0.000
E74.8 Other specified disorders of carbohydrate metabolism	0.005	0.995	0.000
E74.4 Disorders of pyruvate metabolism and gluconeogenesis	0.005	0.995	0.000
E74.2 Disorders of galactose metabolism	0.005	0.995	0.000
E74.1 Disorders of fructose metabolism	0.005	0.995	0.000
E74.0 Glycogen storage disease	0.005	0.995	0.000
I78.8 Other diseases of capillaries	0.005	0.995	0.000
I79.8 Other disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.004	0.995	0.000
I79.1 Aortitis in diseases classified elsewhere	0.004	0.995	0.000
I79.0 Aneurysm of aorta in diseases classified elsewhere	0.004	0.995	0.000
E70.9 Disorder of aromatic amino-acid metabolism, unspecified	0.004	0.995	0.000
E70.8 Other disorders of aromatic amino-acid metabolism	0.004	0.995	0.000
E70.3 Albinism	0.004	0.995	0.000
E70.2 Disorders of tyrosine metabolism	0.004	0.995	0.000
E70.1 Other hyperphenylalaninaemias	0.004	0.995	0.000
E70.0 Classical phenylketonuria	0.004	0.995	0.000
E71.3 Disorders of fatty-acid metabolism	0.004	0.995	0.000
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified	0.004	0.995	0.000
E71.1 Other disorders of branched-chain amino-acid metabolism	0.004	0.995	0.000
E71.0 Maple-syrup-urine disease	0.004	0.995	0.000
E72.9 Disorder of amino-acid metabolism, unspecified	0.004	0.995	0.000
E72.8 Other specified disorders of amino-acid metabolism	0.004	0.995	0.000
E72.5 Disorders of glycine metabolism	0.004	0.995	0.000
E72.4 Disorders of ornithine metabolism	0.004	0.995	0.000
E72.3 Disorders of lysine and hydroxylysine metabolism	0.004	0.995	0.000
E72.2 Disorders of urea cycle metabolism	0.004	0.995	0.000
E72.1 Disorders of sulphur-bearing amino-acid metabolism	0.004	0.995	0.000
E72.0 Disorders of amino-acid transport	0.004	0.995	0.000
E75.6 Lipid storage disorder, unspecified	0.004	0.995	0.000
E75.5 Other lipid storage disorders	0.004	0.995	0.000
E75.4 Neuronal ceroid lipofuscinosis	0.004	0.995	0.000
E75.3 Sphingolipidosis, unspecified	0.004	0.995	0.000
E75.2 Other sphingolipidosis	0.004	0.995	0.000
E75.1 Other gangliosidosis	0.004	0.995	0.000
E75.0 GM2 gangliosidosis	0.004	0.995	0.000
E76.9 Disorder of glucosaminoglycan metabolism, unspecified	0.004	0.995	0.000
E76.8 Other disorders of glucosaminoglycan metabolism	0.004	0.995	0.000
E76.3 Mucopolysaccharidosis, unspecified	0.004	0.995	0.000
E76.2 Other mucopolysaccharidoses	0.004	0.995	0.000
E76.1 Mucopolysaccharidosis, type II	0.004	0.995	0.000
E76.0 Mucopolysaccharidosis, type I	0.004	0.995	0.000
E77.9 Disorder of glycoprotein metabolism, unspecified	0.004	0.995	0.000
E77.8 Other disorders of glycoprotein metabolism	0.004	0.995	0.000
E77.1 Defects in glycoprotein degradation	0.004	0.995	0.000
E77.0 Defects in posttranslational modification of lysosomal enzymes	0.004	0.995	0.000
E79.9 Disorder of purine and pyrimidine metabolism, unspecified	0.004	0.995	0.000
E79.8 Other disorders of purine and pyrimidine metabolism	0.004	0.995	0.000
E79.1 Lesch-Nyhan syndrome	0.004	0.995	0.000
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease	0.004	0.995	0.000
E84.9 Cystic fibrosis, unspecified	0.004	0.995	0.000
E84.8 Cystic fibrosis with other manifestations	0.004	0.995	0.000
E84.1 Cystic fibrosis with intestinal manifestations	0.004	0.995	0.000
E84.0 Cystic fibrosis with pulmonary manifestations	0.004	0.995	0.000
I78.9 Disease of capillaries, unspecified	0.004	0.995	0.000
S30.0 Contusion of lower back and pelvis	0.005	0.995	0.000
E88.2 Lipomatosis, not elsewhere classified	0.004	0.995	0.000
E88.9 Metabolic disorder, unspecified	0.004	0.995	0.000
E88.8 Other specified metabolic disorders	0.004	0.995	0.000
E88.3 Tumour lysis syndrome	0.004	0.995	0.000
E88.1 Lipodystrophy, not elsewhere classified	0.004	0.995	0.000
E89.2 Postprocedural hypoparathyroidism	0.004	0.995	0.000
M51.9 Intervertebral disk disorder, unspecified	0.000	0.995	0.004
D18 Haemangioma and lymphangioma, any site	0.000	0.996	0.004
E80.7 Disorder of bilirubin metabolism, unspecified	0.004	0.996	0.000
E80.6 Other disorders of bilirubin metabolism	0.004	0.996	0.000
E80.5 Crigler-Najjar syndrome	0.004	0.996	0.000
E80.3 Defects of catalase and peroxydase	0.004	0.996	0.000
E80.2 Other porphyria	0.004	0.996	0.000
E80.1 Porphyria cutanea tarda	0.004	0.996	0.000
E80.0 Hereditary erythropoietic porphyria	0.004	0.996	0.000
I79.2 Peripheral angiopathy in diseases classified elsewhere	0.004	0.996	0.000
I73 Other peripheral vascular diseases	0.004	0.996	0.000
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified	0.004	0.996	0.000
M16 Coxarthrosis [arthrosis of hip]	0.000	0.996	0.004
S32 Fracture of lumbar spine and pelvis	0.004	0.996	0.000
I70.20 Atherosclerosis of arteries of extremities (without gangrene)	0.004	0.996	0.000
R39 Other symptoms and signs involving the urinary system	0.000	0.996	0.004
M51.3 Other specified intervertebral disk degeneration	0.000	0.996	0.004
M51.1 Lumbar and other intervertebral disk disorders with radiculopathy	0.000	0.996	0.004
I72.4 Aneurysm of artery of lower extremity	0.004	0.996	0.000
Chapter IX Diseases of the circulatory system	0.004	0.996	0.000
I70.21 Atherosclerosis of arteries of extremities (with gangrene)	0.004	0.996	0.000
E80.4 Gilbert's syndrome	0.004	0.996	0.000
E85.8 Other amyloidosis	0.004	0.996	0.000
E85.3 Secondary systemic amyloidosis	0.004	0.996	0.000
E85.2 Heredofamilial amyloidosis, unspecified	0.004	0.996	0.000
E85.1 Neuropathic heredofamilial amyloidosis	0.004	0.996	0.000
E85.0 Nonneuropathic heredofamilial amyloidosis	0.004	0.996	0.000
I70.00 Atherosclerosis of aorta (without gangrene)	0.004	0.996	0.000
S32.51 Fracture of pubis (open)	0.004	0.996	0.000
E73.8 Other lactose intolerance	0.004	0.996	0.000
E73.1 Secondary lactase deficiency	0.004	0.996	0.000
E73.0 Congenital lactase deficiency	0.004	0.996	0.000
R39.8 Other and unspecified symptoms and signs involving the urinary system	0.000	0.996	0.004
M51.4 Schmorl's nodes	0.000	0.996	0.004
I70.01 Atherosclerosis of aorta (with gangrene)	0.004	0.996	0.000
I70.81 Atherosclerosis of other arteries (with gangrene)	0.004	0.996	0.000
I70.80 Atherosclerosis of other arteries (without gangrene)	0.004	0.996	0.000
I70.91 Generalized and unspecified atherosclerosis (with gangrene)	0.004	0.996	0.000
I70.90 Generalized and unspecified atherosclerosis (without gangrene)	0.004	0.996	0.000
I70.11 Atherosclerosis of renal artery (with gangrene)	0.004	0.996	0.000
H80.8 Other otosclerosis	0.004	0.996	0.000
H80.2 Cochlear otosclerosis	0.004	0.996	0.000
H80.1 Otosclerosis involving oval window, obliterative	0.004	0.996	0.000
H80.0 Otosclerosis involving oval window, nonobliterative	0.004	0.996	0.000
I77 Other disorders of arteries and arterioles	0.004	0.996	0.000
S30.7 Multiple superficial injuries of abdomen, lower back and pelvis	0.004	0.996	0.000
E85.4 Organ-limited amyloidosis	0.004	0.996	0.000
I70.10 Atherosclerosis of renal artery (without gangrene)	0.004	0.996	0.000
E89.9 Postprocedural endocrine and metabolic disorder, unspecified	0.004	0.996	0.000
E89.8 Other postprocedural endocrine and metabolic disorders	0.004	0.996	0.000
E89.6 Postprocedural adrenocortical(-medullary) hypofunction	0.004	0.996	0.000
E89.5 Postprocedural testicular hypofunction	0.004	0.996	0.000
E89.4 Postprocedural ovarian failure	0.004	0.996	0.000
E89.1 Postprocedural hypoinsulinaemia	0.004	0.996	0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.004	0.996	0.000
M16.7 Other secondary coxarthrosis	0.000	0.996	0.004
S32.8 Fracture of other and unspecified parts of lumbar spine and pelvis	0.004	0.996	0.000
S82.1 Fracture of upper end of tibia	0.004	0.996	0.000
S92.00 Fracture of calcaneus (closed)	0.004	0.996	0.000
S32.1 Fracture of sacrum	0.004	0.996	0.000
C18.0 Caecum	0.004	0.996	0.000
S30.1 Contusion of abdominal wall	0.004	0.996	0.000
I73.0 Raynaud's syndrome	0.003	0.997	0.000
E85.9 Amyloidosis, unspecified	0.003	0.997	0.000
S30.2 Contusion of external genital organs	0.003	0.997	0.000
S32.80 Fracture of other and unspecified parts of lumbar spine and pelvis (closed)	0.003	0.997	0.000
O47.1 False labour at or after 37 completed weeks of gestation	0.003	0.997	0.000
I73.1 Thromboangiitis obliterans [Buerger]	0.003	0.997	0.000
E89.3 Postprocedural hypopituitarism	0.003	0.997	0.000
M16.6 Other secondary coxarthrosis, bilateral	0.000	0.997	0.003
M16.5 Other posttraumatic coxarthrosis	0.000	0.997	0.003
M16.4 Posttraumatic coxarthrosis, bilateral	0.000	0.997	0.003
M16.2 Coxarthrosis resulting from dysplasia, bilateral	0.000	0.997	0.003
M16.3 Other dysplastic coxarthrosis	0.000	0.997	0.003
S32.2 Fracture of coccyx	0.003	0.997	0.000
S32.10 Fracture of sacrum (closed)	0.003	0.997	0.000
M51.8 Other specified intervertebral disk disorders	0.000	0.997	0.003
R39.2 Extrarenal uraemia	0.000	0.997	0.003
R39.0 Extravasation of urine	0.000	0.997	0.003
M51.19 Lumbar and other intervertebral disc disorders with radiculopathy; site unspecified	0.000	0.997	0.003
M51.16 Intervertebral disc disorders w radiculopathy, lumbar region	0.000	0.997	0.003
M51.37 Other intervertebral disc degeneration, lumbosacral region	0.000	0.997	0.003
D18.1 Lymphangioma, any site	0.000	0.997	0.003
I05-I09 Chronic rheumatic heart diseases	0.003	0.997	0.000
M51.0 Lumbar and other intervertebral disk disorders with myelopathy	0.000	0.997	0.003
S32.7 Multiple fractures of lumbar spine and pelvis	0.003	0.997	0.000
I00-I02 Acute rheumatic fever	0.003	0.997	0.000
H80.9 Otosclerosis, unspecified	0.003	0.997	0.000
S32.3 Fracture of ilium	0.003	0.997	0.000
E73.9 Lactose intolerance, unspecified	0.003	0.997	0.000
I77.8 Other specified disorders of arteries and arterioles	0.003	0.997	0.000
I77.0 Arteriovenous fistula, acquired	0.003	0.997	0.000
I73.8 Other specified peripheral vascular diseases	0.003	0.997	0.000
S31 Open wound of abdomen, lower back and pelvis	0.003	0.997	0.000
K80.1 Calculus of gallbladder with other cholecystitis	0.000	0.997	0.003
I77.5 Necrosis of artery	0.003	0.997	0.000
I77.4 Coeliac artery compression syndrome	0.003	0.997	0.000
I77.3 Arterial fibromuscular dysplasia	0.003	0.997	0.000
I77.2 Rupture of artery	0.003	0.997	0.000
N94.8 Other specified conditions associated with female genital organs and menstrual cycle	0.003	0.997	0.000
M16.9 Coxarthrosis, unspecified	0.000	0.997	0.003
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis	0.003	0.997	0.000
S37 Injury of urinary and pelvic organs	0.003	0.997	0.000
S35 Injury of blood vessels at abdomen, lower back and pelvis level	0.003	0.997	0.000
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level	0.003	0.997	0.000
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis	0.003	0.997	0.000
C18.9 Colon, unspecified	0.003	0.997	0.000
S36 Injury of intra-abdominal organs	0.003	0.997	0.000
S32.81 Fracture of other and unspecified parts of lumbar spine and pelvis (open)	0.003	0.997	0.000
S82.11 Fracture of upper end of tibia (open)	0.003	0.997	0.000
S32.11 Fracture of sacrum (open)	0.003	0.997	0.000
S92.0 Fracture of calcaneus	0.003	0.997	0.000
C18 Malignant neoplasm of colon	0.003	0.997	0.000
S32.4 Fracture of acetabulum	0.003	0.997	0.000
I07 Rheumatic tricuspid valve diseases	0.003	0.997	0.000
I77.1 Stricture of artery	0.003	0.997	0.000
I08 Multiple valve diseases	0.003	0.997	0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis	0.003	0.997	0.000
C18.7 Sigmoid colon	0.003	0.997	0.000
O68.1 Labour and delivery complicated by meconium in amniotic fluid	0.000	0.997	0.003
G59.0 Diabetic mononeuropathy	0.000	0.997	0.003
S32.21 Fracture of coccyx (open)	0.002	0.997	0.000
S32.20 Fracture of coccyx (closed)	0.002	0.997	0.000
C18.1 Appendix	0.003	0.997	0.000
I08.3 Combined disorders of mitral, aortic and tricuspid valves	0.003	0.997	0.000
I08.8 Other multiple valve diseases	0.003	0.997	0.000
I06 Rheumatic aortic valve diseases	0.002	0.997	0.000
S32.71 Multiple fractures of lumbar spine and pelvis (open)	0.002	0.997	0.000
C45.0 Mesothelioma of pleura	0.000	0.997	0.003
I02 Rheumatic chorea	0.002	0.997	0.000
I01 Rheumatic fever with heart involvement	0.002	0.997	0.000
I00 Rheumatic fever without mention of heart involvement	0.002	0.997	0.000
S31.4 Open wound of vagina and vulva	0.002	0.997	0.000
S32.0 Fracture of lumbar vertebra	0.002	0.997	0.000
I09 Other rheumatic heart diseases	0.002	0.997	0.000
S32.31 Fracture of ilium (open)	0.002	0.997	0.000
S39.8 Other specified injuries of abdomen, lower back and pelvis	0.002	0.997	0.000
T93.3 Sequelae of dislocation, sprain and strain of lower limb	0.003	0.997	0.000
B98 Other specified infectious agents as the cause of diseases classified to other chapters	0.000	0.997	0.003
S31.1 Open wound of abdominal wall	0.002	0.997	0.000
S32.70 Multiple fractures of lumbar spine and pelvis (closed)	0.002	0.997	0.000
C18.5 Splenic flexure	0.002	0.997	0.000
S31.8 Open wound of other and unspecified parts of abdomen	0.002	0.997	0.000
S31.7 Multiple open wounds of abdomen, lower back and pelvis	0.002	0.997	0.000
S31.5 Open wound of other and unspecified external genital organs	0.002	0.997	0.000
S31.3 Open wound of scrotum and testes	0.002	0.997	0.000
S31.2 Open wound of penis	0.002	0.997	0.000
S31.0 Open wound of lower back and pelvis	0.002	0.997	0.000
O47.9 False labour, unspecified	0.002	0.997	0.000
O68.9 Labour and delivery complicated by foetal stress, unspecified	0.000	0.998	0.002
Z34.8 Supervision of other normal pregnancy	0.002	0.998	0.000
S36.0 Injury of spleen	0.002	0.998	0.000
I07.1 Tricuspid insufficiency	0.002	0.998	0.000
C18.2 Ascending colon	0.002	0.998	0.000
H25.1 Senile nuclear cataract	0.002	0.998	0.000
S33.7 Sprain and strain of other and unspecified parts of lumbar spine and pelvis	0.002	0.998	0.000
S33.6 Sprain and strain of sacro-iliac joint	0.002	0.998	0.000
S33.5 Sprain and strain of lumbar spine	0.002	0.998	0.000
S33.4 Traumatic rupture of symphysis pubis	0.002	0.998	0.000
S33.3 Dislocation of other and unspecified parts of lumbar spine and pelvis	0.002	0.998	0.000
S33.2 Dislocation of sacro-iliac and sacrococcygeal joint	0.002	0.998	0.000
S33.1 Dislocation of lumbar vertebra	0.002	0.998	0.000
S33.0 Traumatic rupture of lumbar intervertebral disk	0.002	0.998	0.000
S34.8 Injury of other and unspecified nerves at abdomen, lower back and pelvis level	0.002	0.998	0.000
S34.6 Injury of peripheral nerve(s) of abdomen, lower back and pelvis	0.002	0.998	0.000
S34.5 Injury of lumbar, sacral and pelvic sympathetic nerves	0.002	0.998	0.000
S34.4 Injury of lumbosacral plexus	0.002	0.998	0.000
S34.3 Injury of cauda equina	0.002	0.998	0.000
S34.2 Injury of nerve root of lumbar and sacral spine	0.002	0.998	0.000
S34.1 Other injury of lumbar spinal cord	0.002	0.998	0.000
S34.0 Concussion and oedema of lumbar spinal cord	0.002	0.998	0.000
S35.9 Injury of unspecified blood vessel at abdomen, lower back and pelvis level	0.002	0.998	0.000
S35.8 Injury of other blood vessels at abdomen, lower back and pelvis level	0.002	0.998	0.000
S35.7 Injury of multiple blood vessels at abdomen, lower back and pelvis level	0.002	0.998	0.000
S35.5 Injury of iliac blood vessels	0.002	0.998	0.000
S35.4 Injury of renal blood vessels	0.002	0.998	0.000
S35.3 Injury of portal or splenic vein	0.002	0.998	0.000
S35.2 Injury of coeliac or mesenteric artery	0.002	0.998	0.000
S35.1 Injury of inferior vena cava	0.002	0.998	0.000
S35.0 Injury of abdominal aorta	0.002	0.998	0.000
S37.9 Injury of unspecified pelvic organ	0.002	0.998	0.000
S37.8 Injury of other pelvic organs	0.002	0.998	0.000
S37.7 Injury of multiple pelvic organs	0.002	0.998	0.000
S37.6 Injury of uterus	0.002	0.998	0.000
S37.5 Injury of Fallopian tube	0.002	0.998	0.000
S37.4 Injury of ovary	0.002	0.998	0.000
S37.3 Injury of urethra	0.002	0.998	0.000
S37.2 Injury of bladder	0.002	0.998	0.000
S37.1 Injury of ureter	0.002	0.998	0.000
S37.0 Injury of kidney	0.002	0.998	0.000
S38.3 Traumatic amputation of other and unspecified parts of abdomen, lower back and pelvis	0.002	0.998	0.000
S38.2 Traumatic amputation of external genital organs	0.002	0.998	0.000
S38.1 Crushing injury of other and unspecified parts of abdomen, lower back and pelvis	0.002	0.998	0.000
S38.0 Crushing injury of external genital organs	0.002	0.998	0.000
C18.8 Overlapping lesion of colon	0.002	0.998	0.000
I08.0 Disorders of both mitral and aortic valves	0.002	0.998	0.000
S36.9 Injury of unspecified intra-abdominal organ	0.002	0.998	0.000
S36.8 Injury of other intra-abdominal organs	0.002	0.998	0.000
S36.7 Injury of multiple intra-abdominal organs	0.002	0.998	0.000
S36.6 Injury of rectum	0.002	0.998	0.000
S36.5 Injury of colon	0.002	0.998	0.000
S36.4 Injury of small intestine	0.002	0.998	0.000
S36.3 Injury of stomach	0.002	0.998	0.000
S36.2 Injury of pancreas	0.002	0.998	0.000
O47 False labour	0.002	0.998	0.000
S32.30 Fracture of ilium (closed)	0.002	0.998	0.000
M16.0 Primary coxarthrosis, bilateral	0.000	0.998	0.002
S92.01 Fracture of calcaneus (open)	0.002	0.998	0.000
H54.0 Blindness, both eyes	0.000	0.998	0.002
I44.2 Atrioventricular block, complete	0.000	0.998	0.002
S32.41 Fracture of acetabulum (open)	0.002	0.998	0.000
S36.1 Injury of liver or gallbladder	0.002	0.998	0.000
W07.0 Home	0.002	0.998	0.000
C18.3 Hepatic flexure	0.002	0.998	0.000
I05.0 Mitral stenosis	0.002	0.998	0.000
I07.9 Tricuspid valve disease, unspecified	0.002	0.998	0.000
I07.8 Other tricuspid valve diseases	0.002	0.998	0.000
I07.2 Tricuspid stenosis with insufficiency	0.002	0.998	0.000
I07.0 Tricuspid stenosis	0.002	0.998	0.000
Z99.1 Dependence on respirator	0.000	0.998	0.002
I05 Rheumatic mitral valve diseases	0.002	0.998	0.000
I08.9 Multiple valve disease, unspecified	0.002	0.998	0.000
S92 Fracture of foot, except ankle	0.002	0.998	0.000
H72.9 Perforation of tympanic membrane, unspecified	0.000	0.998	0.002
S39.7 Other multiple injuries of abdomen, lower back and pelvis	0.002	0.998	0.000
S39.6 Injury of intra-abdominal organ(s) with pelvic organ(s)	0.002	0.998	0.000
S39.0 Injury of muscle and tendon of abdomen, lower back and pelvis	0.002	0.998	0.000
J90 Pleural effusion, not elsewhere classified	0.002	0.998	0.000
E86 Volume depletion	0.002	0.998	0.000
O36.0 Maternal care for rhesus isoimmunisation	0.002	0.998	0.000
I06.9 Rheumatic aortic valve disease, unspecified	0.002	0.998	0.000
I06.8 Other rheumatic aortic valve diseases	0.002	0.998	0.000
I06.2 Rheumatic aortic stenosis with insufficiency	0.002	0.998	0.000
I06.1 Rheumatic aortic insufficiency	0.002	0.998	0.000
I06.0 Rheumatic aortic stenosis	0.002	0.998	0.000
I34.0 Mitral (valve) insufficiency	0.002	0.998	0.000
K12.3 Oral mucositis (ulcerative)	0.002	0.998	0.000
S32.01 Fracture of lumbar vertebra (open)	0.002	0.998	0.000
I01.9 Acute rheumatic heart disease, unspecified	0.002	0.998	0.000
I01.8 Other acute rheumatic heart disease	0.002	0.998	0.000
I01.2 Acute rheumatic myocarditis	0.002	0.998	0.000
I01.1 Acute rheumatic endocarditis	0.002	0.998	0.000
I01.0 Acute rheumatic pericarditis	0.002	0.998	0.000
I02.9 Rheumatic chorea without heart involvement	0.002	0.998	0.000
I02.0 Rheumatic chorea with heart involvement	0.002	0.998	0.000
I77.9 Disorder of arteries and arterioles, unspecified	0.002	0.998	0.000
S92.2 Fracture of other tarsal bone(s)	0.002	0.998	0.000
S36.00 Injury of spleen (without open wound into cavity)	0.002	0.998	0.000
B98.1 Vibrio vulnificus as the cause of diseases classified to other chapters	0.000	0.998	0.002
I09.8 Other specified rheumatic heart diseases	0.002	0.998	0.000
I09.2 Chronic rheumatic pericarditis	0.002	0.998	0.000
I09.1 Rheumatic diseases of endocardium, valve unspecified	0.002	0.998	0.000
I09.0 Rheumatic myocarditis	0.002	0.998	0.000
Z45 Adjustment and management of implanted device	0.002	0.998	0.000
S92.4 Fracture of great toe	0.002	0.998	0.000
S92.1 Fracture of talus	0.002	0.998	0.000
Z34.0 Supervision of normal first pregnancy	0.002	0.998	0.000
I08.2 Disorders of both aortic and tricuspid valves	0.002	0.998	0.000
S36.01 Injury of spleen (with open wound into cavity)	0.002	0.998	0.000
S92.20 Fracture of other tarsal bone(s) (closed)	0.002	0.998	0.000
I09.9 Rheumatic heart disease, unspecified	0.002	0.998	0.000
S37.01 Injury of kidney (with open wound into cavity)	0.002	0.998	0.000
S37.00 Injury of kidney (without open wound into cavity)	0.002	0.998	0.000
S37.11 Injury of ureter (with open wound into cavity)	0.002	0.998	0.000
S37.10 Injury of ureter (without open wound into cavity)	0.002	0.998	0.000
S37.21 Injury of bladder (with open wound into cavity)	0.002	0.998	0.000
S37.20 Injury of bladder (without open wound into cavity)	0.002	0.998	0.000
S37.31 Injury of urethra (with open wound into cavity)	0.002	0.998	0.000
S37.30 Injury of urethra (without open wound into cavity)	0.002	0.998	0.000
S37.41 Injury of ovary (with open wound into cavity)	0.002	0.998	0.000
S37.40 Injury of ovary (without open wound into cavity)	0.002	0.998	0.000
S37.51 Injury of fallopian tube (with open wound into cavity)	0.002	0.998	0.000
S37.50 Injury of fallopian tube (without open wound into cavity)	0.002	0.998	0.000
S37.61 Injury of uterus (with open wound into cavity)	0.002	0.998	0.000
S37.60 Injury of uterus (without open wound into cavity)	0.002	0.998	0.000
S37.71 Injury of multiple pelvic organs (with open wound into cavity)	0.002	0.998	0.000
S37.70 Injury of multiple pelvic organs (without open wound into cavity)	0.002	0.998	0.000
S37.81 Injury of other pelvic organs (with open wound into cavity)	0.002	0.998	0.000
S37.80 Injury of other pelvic organs (without open wound into cavity)	0.002	0.998	0.000
S37.91 Injury of unspecified pelvic organ (with open wound into cavity)	0.002	0.998	0.000
S37.90 Injury of unspecified pelvic organ (without open wound into cavity)	0.002	0.998	0.000
S36.21 Injury of pancreas (with open wound into cavity)	0.002	0.998	0.000
S36.20 Injury of pancreas (without open wound into cavity)	0.002	0.998	0.000
S36.31 Injury of stomach (with open wound into cavity)	0.002	0.998	0.000
S36.30 Injury of stomach (without open wound into cavity)	0.002	0.998	0.000
S36.41 Injury of small intestine (with open wound into cavity)	0.002	0.998	0.000
S36.40 Injury of small intestine (without open wound into cavity)	0.002	0.998	0.000
S36.51 Injury of colon (with open wound into cavity)	0.002	0.998	0.000
S36.50 Injury of colon (without open wound into cavity)	0.002	0.998	0.000
S36.61 Injury of rectum (with open wound into cavity)	0.002	0.998	0.000
S36.60 Injury of rectum (without open wound into cavity)	0.002	0.998	0.000
S36.71 Injury of multiple intra-abdominal organs (with open wound into cavity)	0.002	0.998	0.000
S36.70 Injury of multiple intra-abdominal organs (without open wound into cavity)	0.002	0.998	0.000
S36.81 Injury of other intra-abdominal organs (with open wound into cavity)	0.002	0.998	0.000
S36.80 Injury of other intra-abdominal organs (without open wound into cavity)	0.002	0.998	0.000
S36.91 Injury of unspecified intra-abdominal organ (with open wound into cavity)	0.002	0.998	0.000
S36.90 Injury of unspecified intra-abdominal organ (without open wound into cavity)	0.002	0.998	0.000
S82.30 Fracture of lower end of tibia (closed)	0.002	0.998	0.000
C45.9 Mesothelioma, unspecified	0.000	0.998	0.002
H02.5 Other disorders affecting eyelid function	0.002	0.998	0.000
I77.6 Arteritis, unspecified	0.002	0.998	0.000
S82.50 Fracture of medial malleolus (closed)	0.002	0.998	0.000
S92.10 Fracture of talus (closed)	0.002	0.998	0.000
S92.7 Multiple fractures of foot	0.002	0.998	0.000
S92.40 Fracture of great toe (closed)	0.002	0.998	0.000
H02.1 Ectropion of eyelid	0.002	0.998	0.000
M20.5 Other deformities of toe(s) (acquired)	0.002	0.998	0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.000	0.998	0.002
I27.0 Primary pulmonary hypertension	0.000	0.998	0.002
S83.2 Tear of meniscus, current	0.002	0.998	0.000
S36.11 Injury of liver or gallbladder (with open wound into cavity)	0.002	0.998	0.000
I05.8 Other mitral valve diseases	0.002	0.998	0.000
W18.3 Sports and athletics area	0.002	0.998	0.000
Z45.2 Adjustment and management of vascular access device	0.002	0.998	0.000
H02 Other disorders of eyelid	0.002	0.998	0.000
S92.9 Fracture of foot, unspecified	0.002	0.998	0.000
Z45.3 Adjustment and management of implanted hearing device	0.002	0.998	0.000
Z34 Supervision of normal pregnancy	0.002	0.998	0.000
O47.0 False labour before 37 completed weeks of gestation	0.002	0.998	0.000
C45 Mesothelioma	0.000	0.998	0.002
I78.1 Naevus, nonneoplastic	0.001	0.998	0.001

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations