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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs516535
log Bayes Factor = 84.2888
Chromosome 6   position 32,942,302  (GRCh37) Explore rs516535 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E10.9 Without complications
0.000 0.000 1.000
K90.0 Coeliac disease
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
E10.3 With ophthalmic complications
0.000 0.000 1.000
E10.1 With ketoacidosis
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.001 0.999
E10-E14 Diabetes mellitus
0.000 0.001 0.999
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.001 0.999
E16 Other disorders of pancreatic internal secretion
0.000 0.001 0.999
E16.2 Hypoglycaemia, unspecified
0.000 0.002 0.998
E10.4 With neurological complications
0.000 0.003 0.997
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.005 0.995
L40.9 Psoriasis, unspecified
0.994 0.006 0.000
E00-E07 Disorders of thyroid gland
0.000 0.007 0.993
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.008 0.992
L40 Psoriasis
0.991 0.009 0.000
E05.9 Thyrotoxicosis, unspecified
0.000 0.010 0.990
L40.5 Arthropathic psoriasis
0.990 0.010 0.000
E40-E46 Malnutrition
0.000 0.023 0.977
E46 Unspecified protein-energy malnutrition
0.000 0.040 0.960
E10.2 With renal complications
0.000 0.047 0.953
L40.8 Other psoriasis
0.923 0.077 0.000
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.098 0.902
E10.5 With peripheral circulatory complications
0.000 0.146 0.854
E13 Other specified diabetes mellitus
0.000 0.148 0.852
E10.8 With unspecified complications
0.000 0.164 0.836
K90 Intestinal malabsorption
0.000 0.184 0.816
K90.9 Intestinal malabsorption, unspecified
0.000 0.223 0.777
E16.1 Other hypoglycaemia
0.000 0.235 0.765
E13.9 Without complications
0.000 0.239 0.761
E07 Other disorders of thyroid
0.000 0.278 0.722
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.716
E15 Nondiabetic hypoglycaemic coma
0.000 0.284 0.716
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.284 0.716
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.284 0.716
E16.4 Abnormal secretion of gastrin
0.000 0.284 0.716
E16.3 Increased secretion of glucagon
0.000 0.284 0.716
E05.5 Thyroid crisis or storm
0.000 0.287 0.713
E05.4 Thyrotoxicosis factitia
0.000 0.287 0.713
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.287 0.713
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.288 0.712
E00 Congenital iodine-deficiency syndrome
0.000 0.288 0.712
L40.4 Guttate psoriasis
0.710 0.289 0.000
L40.2 Acrodermatitis continua
0.710 0.289 0.000
L40.3 Pustulosis palmaris et plantaris
0.705 0.295 0.000
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.300 0.700
E45 Retarded development following protein-energy malnutrition
0.000 0.300 0.700
E43 Unspecified severe protein-energy malnutrition
0.000 0.300 0.700
E42 Marasmic kwashiorkor
0.000 0.300 0.700
E41 Nutritional marasmus
0.000 0.300 0.700
E40 Kwashiorkor
0.000 0.300 0.700
E10.0 With coma
0.000 0.302 0.698
E05.8 Other thyrotoxicosis
0.000 0.313 0.687
E10.7 With multiple complications
0.000 0.314 0.686
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.337 0.663
L40.1 Generalised pustular psoriasis
0.659 0.341 0.000
E10.6 With other specified complications
0.000 0.348 0.651
K90.4 Malabsorption due to intolerance, not elsewhere classified
0.000 0.382 0.618
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.384 0.615
E07.9 Disorder of thyroid, unspecified
0.000 0.388 0.612
E13.8 With unspecified complications
0.000 0.389 0.611
E13.7 With multiple complications
0.000 0.389 0.611
E13.6 With other specified complications
0.000 0.389 0.611
E13.5 With peripheral circulatory complications
0.000 0.389 0.611
E13.4 With neurological complications
0.000 0.389 0.611
E13.2 With renal complications
0.000 0.389 0.611
E13.1 With ketoacidosis
0.000 0.389 0.611
E13.0 With coma
0.000 0.389 0.611
K90.3 Pancreatic steatorrhoea
0.000 0.415 0.585
K90.2 Blind loop syndrome, not elsewhere classified
0.000 0.415 0.585
K90.1 Tropical sprue
0.000 0.415 0.585
E65-E68 Obesity and other hyperalimentation
0.000 0.421 0.579
E13.3 With ophthalmic complications
0.000 0.424 0.576
E14 Unspecified diabetes mellitus
0.000 0.448 0.552
K90.8 Other intestinal malabsorption
0.000 0.456 0.544
E07.1 Dyshormogenetic goitre
0.000 0.482 0.518
E07.0 Hypersecretion of calcitonin
0.000 0.482 0.518
E12.9 Without complications
0.000 0.486 0.514
E12.8 With unspecified complications
0.000 0.486 0.514
E12.7 With multiple complications
0.000 0.486 0.514
E12.6 With other specified complications
0.000 0.486 0.514
E12.5 With peripheral circulatory complications
0.000 0.486 0.514
E12.4 With neurological complications
0.000 0.486 0.514
E12.3 With ophthalmic complications
0.000 0.486 0.514
E12.2 With renal complications
0.000 0.486 0.514
E12.1 With ketoacidosis
0.000 0.486 0.514
E12.0 With coma
0.000 0.486 0.514
E20-E35 Disorders of other endocrine glands
0.000 0.488 0.512
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.489 0.511
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.489 0.511
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.489 0.511
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.489 0.511
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.489 0.511
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.489 0.511
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.489 0.511
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.489 0.511
E44.1 Mild protein-energy malnutrition
0.000 0.498 0.502
E44.0 Moderate protein-energy malnutrition
0.000 0.498 0.502
E06 Thyroiditis
0.000 0.516 0.484
E65 Localised adiposity
0.000 0.518 0.482
E14.3 With ophthalmic complications
0.000 0.536 0.464
L40.0 Psoriasis vulgaris
0.450 0.550 0.000
E27 Other disorders of adrenal gland
0.000 0.558 0.442
E14.8 With unspecified complications
0.000 0.569 0.431
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.570 0.430
E22 Hyperfunction of pituitary gland
0.000 0.573 0.427
E26 Hyperaldosteronism
0.000 0.579 0.421
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.584 0.415
E67 Other hyperalimentation
0.000 0.585 0.415
E68 Sequelae of hyperalimentation
0.000 0.585 0.415
E14.6 With other specified complications
0.000 0.588 0.412
E14.7 With multiple complications
0.000 0.604 0.396
E14.0 With coma
0.000 0.604 0.396
E14.4 With neurological complications
0.000 0.611 0.389
E27.1 Primary adrenocortical insufficiency
0.000 0.613 0.387
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.616 0.384
E14.2 Withrenal complications
0.000 0.620 0.380
E50-E64 Other nutritional deficiencies
0.000 0.630 0.370
E22.1 Hyperprolactinaemia
0.000 0.632 0.368
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.633 0.367
E32 Diseases of thymus
0.000 0.633 0.367
E30 Disorders of puberty, not elsewhere classified
0.000 0.633 0.367
E14.5 With peripheral circulatory complications
0.000 0.634 0.365
E07.8 Other specified disorders of thyroid
0.000 0.638 0.362
E21.0 Primary hyperparathyroidism
0.000 0.641 0.359
E25 Adrenogenital disorders
0.000 0.643 0.357
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.646 0.354
E06.4 Drug-induced thyroiditis
0.000 0.653 0.347
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.653 0.347
E06.0 Acute thyroiditis
0.000 0.653 0.347
E06.1 Subacute thyroiditis
0.000 0.654 0.346
E26.0 Primary hyperaldosteronism
0.000 0.655 0.344
L40-L45 Papulosquamous disorders
0.341 0.659 0.000
E14.1 With ketoacidosis
0.000 0.659 0.340
E34 Other endocrine disorders
0.000 0.662 0.338
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.662 0.338
E21.2 Other hyperparathyroidism
0.000 0.662 0.338
E31 Polyglandular dysfunction
0.000 0.663 0.337
E29 Testicular dysfunction
0.000 0.666 0.334
E24 Cushing's syndrome
0.000 0.670 0.330
E06.5 Other chronic thyroiditis
0.000 0.677 0.323
E27.9 Disorder of adrenal gland, unspecified
0.000 0.679 0.321
E26.9 Hyperaldosteronism, unspecified
0.000 0.681 0.318
E27.5 Adrenomedullary hyperfunction
0.000 0.683 0.317
E27.0 Other adrenocortical overactivity
0.000 0.683 0.317
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.685 0.315
E06.3 Autoimmune thyroiditis
0.000 0.686 0.314
E21.4 Other specified disorders of parathyroid gland
0.000 0.692 0.308
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.693 0.306
E22.8 Other hyperfunction of pituitary gland
0.000 0.693 0.306
E03 Other hypothyroidism
0.000 0.694 0.306
E58 Dietary calcium deficiency
0.000 0.695 0.305
E26.8 Other hyperaldosteronism
0.000 0.698 0.302
E26.1 Secondary hyperaldosteronism
0.000 0.698 0.302
E67.8 Other specified hyperalimentation
0.000 0.702 0.298
E67.3 Hypervitaminosis D
0.000 0.702 0.298
E67.2 Megavitamin-B6 syndrome
0.000 0.702 0.298
E67.1 Hypercarotenaemia
0.000 0.702 0.298
E67.0 Hypervitaminosis A
0.000 0.702 0.298
E27.2 Addisonian crisis
0.000 0.704 0.296
E21.3 Hyperparathyroidism, unspecified
0.000 0.720 0.280
E34.8 Other specified endocrine disorders
0.000 0.722 0.278
L42 Pityriasis rosea
0.278 0.722 0.000
E20 Hypoparathyroidism
0.000 0.730 0.269
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.734 0.265
E63 Other nutritional deficiencies
0.000 0.734 0.265
E50 Vitamin A deficiency
0.000 0.734 0.265
E60 Dietary zinc deficiency
0.000 0.734 0.265
E59 Dietary selenium deficiency
0.000 0.734 0.265
E54 Ascorbic acid deficiency
0.000 0.734 0.265
E52 Niacin deficiency [pellagra]
0.000 0.734 0.265
E30.9 Disorder of puberty, unspecified
0.000 0.737 0.263
E30.8 Other disorders of puberty
0.000 0.737 0.263
E30.1 Precocious puberty
0.000 0.737 0.263
E30.0 Delayed puberty
0.000 0.737 0.263
E32.9 Disease of thymus, unspecified
0.000 0.737 0.263
E32.8 Other diseases of thymus
0.000 0.737 0.263
E32.1 Abscess of thymus
0.000 0.737 0.263
E32.0 Persistent hyperplasia of thymus
0.000 0.737 0.263
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.737 0.263
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.737 0.263
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.737 0.263
E22.0 Acromegaly and pituitary gigantism
0.000 0.739 0.261
E56 Other vitamin deficiencies
0.000 0.740 0.260
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.741 0.259
E25.9 Adrenogenital disorder, unspecified
0.000 0.744 0.256
E25.8 Other adrenogenital disorders
0.000 0.744 0.256
E24.8 Other Cushing's syndrome
0.000 0.753 0.247
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency
0.000 0.754 0.246
E34.0 Carcinoid syndrome
0.000 0.755 0.244
L44 Other papulosquamous disorders
0.244 0.756 0.000
L41 Parapsoriasis
0.244 0.756 0.000
L45 Papulosquamous disorders in diseases classified elsewhere
0.244 0.756 0.000
E34.5 Androgen resistance syndrome
0.000 0.757 0.242
E34.4 Constitutional tall stature
0.000 0.757 0.242
E34.2 Ectopic hormone secretion, not elsewhere classified
0.000 0.757 0.242
E34.1 Other hypersecretion of intestinal hormones
0.000 0.757 0.242
E31.9 Polyglandular dysfunction, unspecified
0.000 0.758 0.242
E31.8 Other polyglandular dysfunction
0.000 0.758 0.242
E31.1 Polyglandular hyperfunction
0.000 0.758 0.242
E24.0 Pituitary-dependent Cushing's disease
0.000 0.758 0.242
E29.9 Testicular dysfunction, unspecified
0.000 0.760 0.239
E29.8 Other testicular dysfunction
0.000 0.760 0.239
E29.0 Testicular hyperfunction
0.000 0.760 0.239
E24.2 Drug-induced Cushing's syndrome
0.000 0.761 0.238
E06.9 Thyroiditis, unspecified
0.000 0.762 0.237
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.763 0.237
E24.3 Ectopic ACTH syndrome
0.000 0.763 0.237
E24.1 Nelson's syndrome
0.000 0.763 0.237
E51 Thiamine deficiency
0.000 0.765 0.234
E03.8 Other specified hypothyroidism
0.000 0.770 0.230
E27.8 Other specified disorders of adrenal gland
0.000 0.775 0.225
E34.3 Short stature, not elsewhere classified
0.000 0.776 0.224
E03.5 Myxoedema coma
0.000 0.781 0.219
E03.4 Atrophy of thyroid (acquired)
0.000 0.781 0.219
E03.3 Postinfectious hypothyroidism
0.000 0.781 0.219
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.784 0.216
E31.0 Autoimmune polyglandular failure
0.000 0.787 0.212
E55 Vitamin D deficiency
0.000 0.790 0.210
E61 Deficiency of other nutrient elements
0.000 0.792 0.207
E29.1 Testicular hypofunction
0.000 0.794 0.206
E03.1 Congenital hypothyroidism without goitre
0.000 0.795 0.204
E20.1 Pseudohypoparathyroidism
0.000 0.806 0.193
E20.0 Idiopathic hypoparathyroidism
0.000 0.806 0.193
E50.9 Vitamin A deficiency, unspecified
0.000 0.809 0.190
E50.8 Other manifestations of vitamin A deficiency
0.000 0.809 0.190
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.809 0.190
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.809 0.190
E50.5 Vitamin A deficiency with night blindness
0.000 0.809 0.190
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.809 0.190
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.809 0.190
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.809 0.190
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.809 0.190
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.809 0.190
E63.9 Nutritional deficiency, unspecified
0.000 0.809 0.190
E63.8 Other specified nutritional deficiencies
0.000 0.809 0.190
E63.1 Imbalance of constituents of food intake
0.000 0.809 0.190
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.809 0.190
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.809 0.190
E64.8 Sequelae of other nutritional deficiencies
0.000 0.809 0.190
E64.3 Sequelae of rickets
0.000 0.809 0.190
E64.2 Sequelae of vitamin C deficiency
0.000 0.809 0.190
E64.1 Sequelae of vitamin A deficiency
0.000 0.809 0.190
E64.0 Sequelae of protein-energy malnutrition
0.000 0.809 0.190
E56.9 Vitamin deficiency, unspecified
0.000 0.813 0.186
E56.8 Deficiency of other vitamins
0.000 0.813 0.186
E56.0 Deficiency of vitamin E
0.000 0.813 0.186
E28 Ovarian dysfunction
0.001 0.815 0.185
E56.1 Deficiency of vitamin K
0.000 0.819 0.181
L41.9 Parapsoriasis, unspecified
0.175 0.824 0.000
L41.8 Other parapsoriasis
0.175 0.824 0.000
L41.5 Retiform parapsoriasis
0.175 0.824 0.000
L41.4 Large plaque parapsoriasis
0.175 0.824 0.000
L41.3 Small plaque parapsoriasis
0.175 0.824 0.000
L41.2 Lymphomatoid papulosis
0.175 0.824 0.000
L41.1 Pityriasis lichenoides chronica
0.175 0.824 0.000
L41.0 Pityriasis lichenoides et varioliformis acuta
0.175 0.824 0.000
L44.9 Papulosquamous disorder, unspecified
0.175 0.824 0.000
L44.8 Other specified papulosquamous disorders
0.175 0.824 0.000
L44.4 Infantile papular acrodermatitis [Giannotti-Crosti]
0.175 0.824 0.000
L44.3 Lichen ruber moniliformis
0.175 0.824 0.000
L44.2 Lichen striatus
0.175 0.824 0.000
L44.1 Lichen nitidus
0.175 0.824 0.000
L44.0 Pityriasis rubra pilaris
0.175 0.824 0.000
E20.8 Other hypoparathyroidism
0.000 0.825 0.175
E24.9 Cushing's syndrome, unspecified
0.000 0.828 0.172
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.828 0.172
E34.9 Endocrine disorder, unspecified
0.000 0.831 0.168
E51.9 Thiamine deficiency, unspecified
0.000 0.831 0.168
E51.8 Other manifestations of thiamine deficiency
0.000 0.831 0.168
E51.1 Beriberi
0.000 0.831 0.168
E55.0 Rickets, active
0.000 0.849 0.150
E61.9 Deficiency of nutrient element, unspecified
0.000 0.851 0.149
E61.8 Deficiency of other specified nutrient elements
0.000 0.851 0.149
E61.7 Deficiency of multiple nutrient elements
0.000 0.851 0.149
E61.6 Vanadium deficiency
0.000 0.851 0.149
E61.5 Molybdenum deficiency
0.000 0.851 0.149
E61.4 Chromium deficiency
0.000 0.851 0.149
E61.3 Manganese deficiency
0.000 0.851 0.149
E61.0 Copper deficiency
0.000 0.851 0.149
E53 Deficiency of other B group vitamins
0.000 0.853 0.147
L43 Lichen planus
0.138 0.862 0.000
E51.2 Wernicke's encephalopathy
0.000 0.862 0.137
E28.9 Ovarian dysfunction, unspecified
0.001 0.867 0.132
E28.8 Other ovarian dysfunction
0.001 0.867 0.132
E28.1 Androgen excess
0.001 0.867 0.132
E28.0 Oestrogen excess
0.001 0.867 0.132
E20.9 Hypoparathyroidism, unspecified
0.001 0.870 0.130
E61.2 Magnesium deficiency
0.000 0.870 0.130
C91.1 Chronic lymphocytic leukaemia
0.000 0.872 0.128
E23 Hypofunction and other disorders of pituitary gland
0.000 0.875 0.125
E61.1 Iron deficiency
0.000 0.880 0.119
E14.9 Without complications
0.000 0.889 0.111
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.106 0.894 0.000
E53.1 Pyridoxine deficiency
0.000 0.894 0.105
E53.0 Riboflavin deficiency
0.000 0.894 0.105
E28.3 Primary ovarian failure
0.001 0.896 0.103
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.104 0.896 0.000
R06.8 Other and unspecified abnormalities of breathing
0.104 0.896 0.000
T39.1 4-Aminophenol derivatives
0.103 0.897 0.000
L43.3 Subacute (active) lichen planus
0.099 0.901 0.000
L43.2 Lichenoid drug reaction
0.099 0.901 0.000
L43.1 Bullous lichen planus
0.099 0.901 0.000
L43.0 Hypertrophic lichen planus
0.099 0.901 0.000
E04 Other non-toxic goitre
0.000 0.901 0.099
E53.9 Vitamin B deficiency, unspecified
0.000 0.901 0.098
E55.9 Vitamin D deficiency, unspecified
0.000 0.905 0.095
L43.8 Other lichen planus
0.090 0.910 0.000
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.910 0.090
E23.1 Drug-induced hypopituitarism
0.000 0.910 0.090
E23.7 Disorder of pituitary gland, unspecified
0.000 0.911 0.089
T39.0 Salicylates
0.080 0.920 0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified
0.078 0.921 0.000
T39.4 Antirheumatics, not elsewhere classified
0.075 0.925 0.000
T39.2 Pyrazolone derivatives
0.075 0.925 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.072 0.928 0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified
0.071 0.929 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.071 0.929 0.000
E04.8 Other specified non-toxic goitre
0.000 0.929 0.071
E66 Obesity
0.000 0.933 0.067
T43.3 Phenothiazine antipsychotics and neuroleptics
0.067 0.933 0.000
T43.2 Other and unspecified antidepressants
0.065 0.935 0.000
E23.2 Diabetes insipidus
0.000 0.936 0.064
E23.6 Other disorders of pituitary gland
0.001 0.937 0.062
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.062 0.938 0.000
T43.5 Other and unspecified antipsychotics and neuroleptics
0.061 0.939 0.000
E04.9 Non-toxic goitre, unspecified
0.000 0.941 0.059
H36.0 Diabetic retinopathy
0.000 0.942 0.058
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.057 0.943 0.000
T43.4 Butyrophenone and thioxanthene neuroleptics
0.056 0.944 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.055 0.944 0.000
E11 Non-insulin-dependent diabetes mellitus
0.000 0.945 0.055
T36 Poisoning by systemic antibiotics
0.054 0.945 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.054 0.945 0.000
T43.6 Psychostimulants with abuse potential
0.053 0.947 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.052 0.948 0.000
K90-K93 Other diseases of the digestive system
0.000 0.948 0.052
T41 Poisoning by anaesthetics and therapeutic gases
0.052 0.948 0.000
T43.9 Psychotropic drug, unspecified
0.051 0.949 0.000
T43.8 Other psychotropic drugs, not elsewhere classified
0.051 0.949 0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants
0.051 0.949 0.000
E11.5 With peripheral circulatory complications
0.000 0.949 0.051
T42.4 Benzodiazepines
0.051 0.949 0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.050 0.950 0.000
T42.1 Iminostilbenes
0.049 0.951 0.000
E66.1 Drug-induced obesity
0.000 0.951 0.048
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.048 0.952 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.047 0.953 0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants
0.045 0.954 0.000
T47.2 Stimulant laxatives
0.045 0.955 0.000
T38.1 Thyroid hormones and substitutes
0.045 0.955 0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified
0.045 0.955 0.000
T42.5 Mixed antiepileptics, not elsewhere classified
0.045 0.955 0.000
T42.2 Succinimides and oxazolidinediones
0.045 0.955 0.000
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified
0.045 0.955 0.000
C91 Lymphoid leukaemia
0.000 0.956 0.044
T42.0 Hydantoin derivatives
0.044 0.956 0.000
T37.8 Other specified systemic anti-infectives and antiparasitics
0.043 0.956 0.000
E66.0 Obesity due to excess calories
0.000 0.957 0.043
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.043 0.957 0.000
T36.3 Macrolides
0.041 0.959 0.000
T42.3 Barbiturates
0.041 0.959 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.041 0.959 0.000
T38.9 Other and unspecified hormone antagonists
0.041 0.959 0.000
T38.7 Androgens and anabolic congeners
0.041 0.959 0.000
T38.5 Other oestrogens and progestogens
0.041 0.959 0.000
T38.4 Oral contraceptives
0.041 0.959 0.000
T38.2 Antithyroid drugs
0.041 0.959 0.000
T38.0 Glucocorticoids and synthetic analogues
0.041 0.959 0.000
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs
0.041 0.959 0.000
T37.9 Systemic anti-infective and antiparasitic, unspecified
0.040 0.960 0.000
T37.5 Antiviral drugs
0.040 0.960 0.000
T37.4 Anthelminthics
0.040 0.960 0.000
T37.3 Other antiprotozoal drugs
0.040 0.960 0.000
T37.2 Antimalarials and drugs acting on other blood protozoa
0.040 0.960 0.000
T37.1 Antimycobacterial drugs
0.040 0.960 0.000
T37.0 Sulphonamides
0.040 0.960 0.000
T47.0 Histamine H(2)-receptor antagonists
0.040 0.960 0.000
T36.0 Penicillins
0.040 0.960 0.000
T47.4 Other laxatives
0.040 0.960 0.000
E11.7 With multiple complications
0.000 0.960 0.039
T36.9 Systemic antibiotic, unspecified
0.039 0.961 0.000
T36.8 Other systemic antibiotics
0.039 0.961 0.000
T36.7 Antifungal antibiotics, systemically used
0.039 0.961 0.000
T36.6 Rifamycins
0.039 0.961 0.000
T36.5 Aminoglycosides
0.039 0.961 0.000
T36.4 Tetracyclines
0.039 0.961 0.000
T36.2 Chloramphenicol group
0.039 0.961 0.000
T36.1 Cefalosporins and other Beta-lactam antibiotics
0.039 0.961 0.000
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified
0.039 0.961 0.000
T47.8 Other agents primarily affecting the gastro-intestinal system
0.039 0.961 0.000
T47.7 Emetics
0.039 0.961 0.000
T47.6 Antidiarrhoeal drugs
0.039 0.961 0.000
T47.5 Digestants
0.039 0.961 0.000
T47.3 Saline and osmotic laxatives
0.039 0.961 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.039 0.961 0.000
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified
0.038 0.962 0.000
T49.9 Topical agent, unspecified
0.038 0.962 0.000
T49.8 Other topical agents
0.038 0.962 0.000
T49.7 Dental drugs, topically applied
0.038 0.962 0.000
T49.6 Otorhinolaryngological drugs and preparations
0.038 0.962 0.000
T49.5 Ophthalmological drugs and preparations
0.038 0.962 0.000
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations
0.038 0.962 0.000
T49.3 Emollients, demulcents and protectants
0.038 0.962 0.000
T49.2 Local astringents and local detergents
0.038 0.962 0.000
T49.1 Antipruritics
0.038 0.962 0.000
K93 Disorders of other digestive organs in diseases classified elsewhere
0.000 0.962 0.038
E66.2 Extreme obesity with alveolar hypoventilation
0.000 0.962 0.038
T41.5 Therapeutic gases
0.037 0.962 0.000
T41.4 Anaesthetic, unspecified
0.037 0.962 0.000
T41.3 Local anaesthetics
0.037 0.962 0.000
T41.2 Other and unspecified general anaesthetics
0.037 0.962 0.000
T41.1 Intravenous anaesthetics
0.037 0.962 0.000
T41.0 Inhaled anaesthetics
0.037 0.962 0.000
E23.0 Hypopituitarism
0.000 0.963 0.036
T38.8 Other and unspecified hormones and their synthetic substitutes
0.036 0.964 0.000
C91.0 Acute lymphoblastic leukaemia
0.000 0.964 0.036
T45.0 Antiallergic and antiemetic drugs
0.036 0.964 0.000
T45.1 Antineoplastic and immunosuppressive drugs
0.035 0.965 0.000
E28.2 Polycystic ovarian syndrome
0.001 0.965 0.034
T45.9 Primarily systemic and haematological agent, unspecified
0.034 0.965 0.000
T45.8 Other primarily systemic and haematological agents
0.034 0.965 0.000
T45.7 Anticoagulant antagonists, vitamin K and other coagulants
0.034 0.965 0.000
T45.6 Fibrinolysis-affecting drugs
0.034 0.965 0.000
T45.4 Iron and its compounds
0.034 0.965 0.000
T45.3 Enzymes, not elsewhere classified
0.034 0.965 0.000
T48.7 Other and unspecified agents primarily acting on the respiratory system
0.034 0.966 0.000
T48.5 Anti-common-cold drugs
0.034 0.966 0.000
T48.4 Expectorants
0.034 0.966 0.000
T48.3 Antitussives
0.034 0.966 0.000
T48.2 Other and unspecified agents primarily acting on muscles
0.034 0.966 0.000
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]
0.034 0.966 0.000
T48.0 Oxytocic drugs
0.034 0.966 0.000
R06 Abnormalities of breathing
0.034 0.966 0.000
E11.8 With unspecified complications
0.000 0.967 0.033
T45.5 Anticoagulants
0.033 0.967 0.000
T50.1 Loop [high-ceiling] diuretics
0.033 0.967 0.000
T44.9 Other and unspecified drugs primarily affecting the nervous system
0.033 0.967 0.000
T47.1 Other antacids and anti-gastric-secretion drugs
0.032 0.968 0.000
C91.8 Mature B-cell leukaemia Burkitt-type
0.000 0.968 0.032
C91.7 Other lymphoid leukaemia
0.000 0.968 0.032
C91.6 Prolymphocytic leukaemia of T-cell type
0.000 0.968 0.032
C91.3 Prolymphocytic leukaemia
0.000 0.968 0.032
C91.2 Subacute lymphocytic leukaemia
0.000 0.968 0.032
E11.6 With other specified complications
0.000 0.968 0.032
C91.9 Lymphoid leukaemia, unspecified
0.000 0.968 0.031
E11.2 With renal complications
0.000 0.969 0.031
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified
0.031 0.969 0.000
C91.5 Adult T-cell leukaemia
0.000 0.969 0.031
T50.8 Diagnostic agents
0.031 0.969 0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified
0.031 0.969 0.000
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified
0.031 0.969 0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified
0.031 0.969 0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified
0.031 0.969 0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified
0.031 0.969 0.000
T44.1 Other parasympathomimetics [cholinergics]
0.031 0.969 0.000
T44.0 Anticholinesterase agents
0.031 0.969 0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics
0.030 0.969 0.000
E04.2 Non-toxic multinodular goitre
0.000 0.969 0.030
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.031 0.969 0.000
R06.5 Mouth breathing
0.030 0.970 0.000
T46.5 Other antihypertensive drugs, not elsewhere classified
0.030 0.970 0.000
R06.1 Stridor
0.030 0.970 0.000
T50.7 Analeptics and opioid receptor antagonists
0.030 0.970 0.000
T50.5 Appetite depressants
0.030 0.970 0.000
T50.3 Electrolytic, caloric and water-balance agents
0.030 0.970 0.000
T50.0 Mineralocorticoids and their antagonists
0.030 0.970 0.000
E11.0 With coma
0.000 0.970 0.029
T46.2 Other antidysrhythmic drugs, not elsewhere classified
0.029 0.971 0.000
T48.6 Antiasthmatics, not elsewhere classified
0.029 0.971 0.000
E04.0 Non-toxic diffuse goitre
0.001 0.971 0.028
T50.4 Drugs affecting uric acid metabolism
0.028 0.971 0.000
T45.2 Vitamins, not elsewhere classified
0.028 0.972 0.000
T46.3 Coronary vasodilators, not elsewhere classified
0.028 0.972 0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action
0.028 0.972 0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system
0.028 0.972 0.000
T46.8 Antivaricose drugs, including sclerosing agents
0.028 0.972 0.000
T46.7 Peripheral vasodilators
0.028 0.972 0.000
K93.8 Disorders of other specified digestive organs in diseases classified elsewhere
0.000 0.973 0.027
K93.1 Megacolon in Chagas' disease
0.000 0.973 0.027
K93.0 Tuberculous disorders of intestines, peritoneum and mesenteric glands
0.000 0.973 0.027
M07.30 Other psoriatic arthropathies (Multiple sites)
0.027 0.973 0.000
T50.6 Antidotes and chelating agents, not elsewhere classified
0.027 0.973 0.000
E04.1 Non-toxic single thyroid nodule
0.000 0.973 0.027
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs
0.025 0.974 0.000
M07.3 Other psoriatic arthropathies
0.025 0.975 0.000
E11.1 With ketoacidosis
0.000 0.975 0.025
H36 Retinal disorders in diseases classified elsewhere
0.000 0.975 0.025
R06.7 Sneezing
0.024 0.976 0.000
R06.3 Periodic breathing
0.024 0.976 0.000
R06.4 Hyperventilation
0.024 0.976 0.000
M07.39 Other psoriatic arthropathies (Site unspecified)
0.024 0.976 0.000
T46.4 Angiotensin-converting-enzyme inhibitors
0.023 0.977 0.000
T40.6 Other and unspecified narcotics
0.023 0.977 0.000
E11.3 With ophthalmic complications
0.000 0.978 0.022
T40.1 Heroin
0.022 0.978 0.000
T40.9 Other and unspecified psychodysleptics [hallucinogens]
0.022 0.978 0.000
T40.8 Lysergide [LSD]
0.022 0.978 0.000
T40.7 Cannabis (derivatives)
0.022 0.978 0.000
T40.3 Methadone
0.022 0.978 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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