TreeWAS – Variant ID: rs538174

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
K70.9 Alcoholic liver disease, unspecified	0.083	0.917	0.000
K70 Alcoholic liver disease	0.081	0.919	0.000
K70.0 Alcoholic fatty liver	0.080	0.920	0.000
K70.3 Alcoholic cirrhosis of liver	0.072	0.928	0.000
K70.4 Alcoholic hepatic failure	0.071	0.929	0.000
K70.2 Alcoholic fibrosis and sclerosis of liver	0.058	0.942	0.000
K70.1 Alcoholic hepatitis	0.046	0.953	0.000
M81.99 Osteoporosis, unspecified (Site unspecified)	0.000	0.955	0.045
M81.9 Osteoporosis, unspecified	0.000	0.955	0.045
M81.90 Osteoporosis, unspecified (Multiple sites)	0.000	0.957	0.043
M81.97 Osteoporosis, unspecified (Ankle and foot)	0.000	0.963	0.037
M81.98 Osteoporosis, unspecified (Other)	0.000	0.963	0.037
M81.95 Osteoporosis, unspecified (Pelvic region and thigh)	0.000	0.967	0.033
M81.94 Osteoporosis, unspecified (Hand)	0.000	0.968	0.032
M81.93 Osteoporosis, unspecified (Forearm)	0.000	0.968	0.032
M81.92 Osteoporosis, unspecified (Upper arm)	0.000	0.968	0.032
M81.91 Osteoporosis, unspecified (Shoulder region)	0.000	0.968	0.032
M81.96 Osteoporosis, unspecified (Lower leg)	0.000	0.968	0.032
M81 Osteoporosis without pathological fracture	0.000	0.973	0.027
M81.4 Drug-induced osteoporosis	0.000	0.976	0.024
M81.40 Drug-induced osteoporosis (Multiple sites)	0.000	0.977	0.023
K70-K77 Diseases of liver	0.021	0.979	0.000
M81.2 Osteoporosis of disuse	0.000	0.980	0.020
M81.8 Other osteoporosis	0.000	0.981	0.019
M81.6 Localised osteoporosis [Lequesne]	0.000	0.981	0.019
M81.5 Idiopathic osteoporosis	0.000	0.981	0.019
M81.3 Postsurgical malabsorption osteoporosis	0.000	0.981	0.019
M81.1 Postoophorectomy osteoporosis	0.000	0.981	0.019
M81.48 Drug-induced osteoporosis (Other)	0.000	0.982	0.017
M81.47 Drug-induced osteoporosis (Ankle and foot)	0.000	0.982	0.017
M81.46 Drug-induced osteoporosis (Lower leg)	0.000	0.982	0.017
M81.45 Drug-induced osteoporosis (Pelvic region and thigh)	0.000	0.982	0.017
M81.44 Drug-induced osteoporosis (Hand)	0.000	0.982	0.017
M81.43 Drug-induced osteoporosis (Forearm)	0.000	0.982	0.017
M81.42 Drug-induced osteoporosis (Upper arm)	0.000	0.982	0.017
M81.41 Drug-induced osteoporosis (Shoulder region)	0.000	0.982	0.017
K75 Other inflammatory liver diseases	0.018	0.982	0.000
K71 Toxic liver disease	0.017	0.983	0.000
K73 Chronic hepatitis, not elsewhere classified	0.017	0.983	0.000
M81.0 Postmenopausal osteoporosis	0.000	0.983	0.016
K75.0 Abscess of liver	0.016	0.984	0.000
K76.8 Other specified diseases of liver	0.016	0.984	0.000
K76 Other diseases of liver	0.016	0.984	0.000
K77 Liver disorders in diseases classified elsewhere	0.015	0.984	0.000
M81.20 Osteoporosis of disuse (Multiple sites)	0.000	0.985	0.015
M81.29 Osteoporosis of disuse (Site unspecified)	0.000	0.985	0.015
M81.28 Osteoporosis of disuse (Other)	0.000	0.985	0.015
M81.27 Osteoporosis of disuse (Ankle and foot)	0.000	0.985	0.015
M81.26 Osteoporosis of disuse (Lower leg)	0.000	0.985	0.015
M81.25 Osteoporosis of disuse (Pelvic region and thigh)	0.000	0.985	0.015
M81.24 Osteoporosis of disuse (Hand)	0.000	0.985	0.015
M81.23 Osteoporosis of disuse (Forearm)	0.000	0.985	0.015
M81.22 Osteoporosis of disuse (Upper arm)	0.000	0.985	0.015
M81.21 Osteoporosis of disuse (Shoulder region)	0.000	0.985	0.015
K71.0 Toxic liver disease with cholestasis	0.014	0.986	0.000
K75.9 Inflammatory liver disease, unspecified	0.014	0.986	0.000
K73.9 Chronic hepatitis, unspecified	0.014	0.986	0.000
M81.19 Postoophorectomy osteoporosis (Site unspecified)	0.000	0.986	0.014
M81.18 Postoophorectomy osteoporosis (Other)	0.000	0.986	0.014
M81.17 Postoophorectomy osteoporosis (Ankle and foot)	0.000	0.986	0.014
M81.16 Postoophorectomy osteoporosis (Lower leg)	0.000	0.986	0.014
M81.15 Postoophorectomy osteoporosis (Pelvic region and thigh)	0.000	0.986	0.014
M81.14 Postoophorectomy osteoporosis (Hand)	0.000	0.986	0.014
M81.13 Postoophorectomy osteoporosis (Forearm)	0.000	0.986	0.014
M81.12 Postoophorectomy osteoporosis (Upper arm)	0.000	0.986	0.014
M81.11 Postoophorectomy osteoporosis (Shoulder region)	0.000	0.986	0.014
M81.10 Postoophorectomy osteoporosis (Multiple sites)	0.000	0.986	0.014
M81.39 Postsurgical malabsorption osteoporosis (Site unspecified)	0.000	0.986	0.014
M81.38 Postsurgical malabsorption osteoporosis (Other)	0.000	0.986	0.014
M81.37 Postsurgical malabsorption osteoporosis (Ankle and foot)	0.000	0.986	0.014
M81.36 Postsurgical malabsorption osteoporosis (Lower leg)	0.000	0.986	0.014
M81.35 Postsurgical malabsorption osteoporosis (Pelvic region and thigh)	0.000	0.986	0.014
M81.34 Postsurgical malabsorption osteoporosis (Hand)	0.000	0.986	0.014
M81.33 Postsurgical malabsorption osteoporosis (Forearm)	0.000	0.986	0.014
M81.32 Postsurgical malabsorption osteoporosis (Upper arm)	0.000	0.986	0.014
M81.31 Postsurgical malabsorption osteoporosis (Shoulder region)	0.000	0.986	0.014
M81.30 Postsurgical malabsorption osteoporosis (Multiple sites)	0.000	0.986	0.014
M81.59 Idiopathic osteoporosis (Site unspecified)	0.000	0.986	0.014
M81.58 Idiopathic osteoporosis (Other)	0.000	0.986	0.014
M81.57 Idiopathic osteoporosis (Ankle and foot)	0.000	0.986	0.014
M81.56 Idiopathic osteoporosis (Lower leg)	0.000	0.986	0.014
M81.55 Idiopathic osteoporosis (Pelvic region and thigh)	0.000	0.986	0.014
M81.54 Idiopathic osteoporosis (Hand)	0.000	0.986	0.014
M81.53 Idiopathic osteoporosis (Forearm)	0.000	0.986	0.014
M81.52 Idiopathic osteoporosis (Upper arm)	0.000	0.986	0.014
M81.51 Idiopathic osteoporosis (Shoulder region)	0.000	0.986	0.014
M81.50 Idiopathic osteoporosis (Multiple sites)	0.000	0.986	0.014
M81.69 Localized osteoporosis [Lequesne] (Site unspecified)	0.000	0.986	0.014
M81.68 Localized osteoporosis [Lequesne] (Other)	0.000	0.986	0.014
M81.67 Localized osteoporosis [Lequesne] (Ankle and foot)	0.000	0.986	0.014
M81.66 Localized osteoporosis [Lequesne] (Lower leg)	0.000	0.986	0.014
M81.65 Localized osteoporosis [Lequesne] (Pelvic region and thigh)	0.000	0.986	0.014
M81.64 Localized osteoporosis [Lequesne] (Hand)	0.000	0.986	0.014
M81.63 Localized osteoporosis [Lequesne] (Forearm)	0.000	0.986	0.014
M81.62 Localized osteoporosis [Lequesne] (Upper arm)	0.000	0.986	0.014
M81.61 Localized osteoporosis [Lequesne] (Shoulder region)	0.000	0.986	0.014
M81.60 Localized osteoporosis [Lequesne] (Multiple sites)	0.000	0.986	0.014
M81.89 Other osteoporosis (Site unspecified)	0.000	0.986	0.014
M81.88 Other osteoporosis (Other)	0.000	0.986	0.014
M81.87 Other osteoporosis (Ankle and foot)	0.000	0.986	0.014
M81.86 Other osteoporosis (Lower leg)	0.000	0.986	0.014
M81.85 Other osteoporosis (Pelvic region and thigh)	0.000	0.986	0.014
M81.84 Other osteoporosis (Hand)	0.000	0.986	0.014
M81.83 Other osteoporosis (Forearm)	0.000	0.986	0.014
M81.82 Other osteoporosis (Upper arm)	0.000	0.986	0.014
M81.81 Other osteoporosis (Shoulder region)	0.000	0.986	0.014
M81.80 Other osteoporosis (Multiple sites)	0.000	0.986	0.014
M81.49 Drug-induced osteoporosis (Site unspecified)	0.000	0.986	0.014
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection	0.014	0.986	0.000
K75.2 Nonspecific reactive hepatitis	0.013	0.987	0.000
K75.1 Phlebitis of portal vein	0.013	0.987	0.000
K71.9 Toxic liver disease, unspecified	0.012	0.987	0.000
K71.8 Toxic liver disease with other disorders of liver	0.012	0.987	0.000
K71.7 Toxic liver disease with fibrosis and cirrhosis of liver	0.012	0.987	0.000
K71.6 Toxic liver disease with hepatitis, not elsewhere classified	0.012	0.987	0.000
K71.5 Toxic liver disease with chronic active hepatitis	0.012	0.987	0.000
K71.4 Toxic liver disease with chronic lobular hepatitis	0.012	0.987	0.000
K71.3 Toxic liver disease with chronic persistent hepatitis	0.012	0.987	0.000
K71.2 Toxic liver disease with acute hepatitis	0.012	0.987	0.000
K73.1 Chronic lobular hepatitis, not elsewhere classified	0.012	0.988	0.000
K73.0 Chronic persistent hepatitis, not elsewhere classified	0.012	0.988	0.000
K73.2 Chronic active hepatitis, not elsewhere classified	0.012	0.988	0.000
M81.08 Postmenopausal osteoporosis (Other)	0.000	0.988	0.012
M81.07 Postmenopausal osteoporosis (Ankle and foot)	0.000	0.988	0.012
M81.06 Postmenopausal osteoporosis (Lower leg)	0.000	0.988	0.012
M81.05 Postmenopausal osteoporosis (Pelvic region and thigh)	0.000	0.988	0.012
M81.04 Postmenopausal osteoporosis (Hand)	0.000	0.988	0.012
M81.03 Postmenopausal osteoporosis (Forearm)	0.000	0.988	0.012
M81.02 Postmenopausal osteoporosis (Upper arm)	0.000	0.988	0.012
M81.01 Postmenopausal osteoporosis (Shoulder region)	0.000	0.988	0.012
M81.00 Postmenopausal osteoporosis (Multiple sites)	0.000	0.988	0.012
C54.1 Endometrium	0.012	0.988	0.000
K73.8 Other chronic hepatitis, not elsewhere classified	0.012	0.988	0.000
K76.7 Hepatorenal syndrome	0.012	0.988	0.000
T86.8 Failure and rejection of other transplanted organs and tissues	0.012	0.988	0.000
K71.1 Toxic liver disease with hepatic necrosis	0.012	0.988	0.000
J44.8 Other specified chronic obstructive pulmonary disease	0.012	0.988	0.000
K75.3 Granulomatous hepatitis, not elsewhere classified	0.012	0.988	0.000
K76.9 Liver disease, unspecified	0.011	0.989	0.000
K76.5 Hepatic veno-occlusive disease	0.011	0.989	0.000
K76.4 Peliosis hepatis	0.011	0.989	0.000
K76.3 Infarction of liver	0.011	0.989	0.000
K76.2 Central haemorrhagic necrosis of liver	0.011	0.989	0.000
K76.1 Chronic passive congestion of liver	0.011	0.989	0.000
K77.8 Liver disorders in other diseases classified elsewhere	0.011	0.989	0.000
K77.0 Liver disorders in infectious and parasitic diseases classified elsewhere	0.011	0.989	0.000
K75.4 Autoimmune hepatitis	0.011	0.989	0.000
I12.0 Hypertensive renal disease with renal failure	0.000	0.989	0.011
Y51.7 Beta-Adrenoreceptor antagonists, not elsewhere classified	0.000	0.990	0.010
M81.09 Postmenopausal osteoporosis (Site unspecified)	0.000	0.990	0.009
K75.8 Other specified inflammatory liver diseases	0.009	0.991	0.000
J44 Other chronic obstructive pulmonary disease	0.009	0.991	0.000
H47.3 Other disorders of optic disk	0.000	0.992	0.008
K72 Hepatic failure, not elsewhere classified	0.007	0.992	0.000
N04.9 Unspecified	0.007	0.993	0.000
I12 Hypertensive renal disease	0.000	0.993	0.007
G70.0 Myasthenia gravis	0.000	0.993	0.007
H47 Other disorders of optic [2nd] nerve and visual pathways	0.000	0.993	0.007
H47.1 Papilloedema, unspecified	0.000	0.993	0.007
K74 Fibrosis and cirrhosis of liver	0.006	0.993	0.000
I12.9 Hypertensive renal disease without renal failure	0.000	0.994	0.006
Z08.8 Follow-up examination after other treatment for malignant neoplasm	0.006	0.994	0.000
H47.2 Optic atrophy	0.000	0.994	0.006
M89.97 Disorder of bone, unspecified (Ankle and foot)	0.006	0.994	0.000
K76.6 Portal hypertension	0.006	0.994	0.000
G12.2 Motor neuron disease	0.000	0.995	0.005
K72.1 Chronic hepatic failure	0.005	0.995	0.000
H47.0 Disorders of optic nerve, not elsewhere classified	0.000	0.995	0.005
H47.7 Disorder of visual pathways, unspecified	0.000	0.995	0.005
H47.6 Disorders of visual cortex	0.000	0.995	0.005
H47.4 Disorders of optic chiasm	0.000	0.995	0.005
H57.1 Ocular pain	0.000	0.995	0.005
K74.0 Hepatic fibrosis	0.005	0.995	0.000
G70 Myasthenia gravis and other myoneural disorders	0.000	0.995	0.005
K74.4 Secondary biliary cirrhosis	0.005	0.995	0.000
K74.2 Hepatic fibrosis with hepatic sclerosis	0.005	0.995	0.000
K74.1 Hepatic sclerosis	0.005	0.995	0.000
C54 Malignant neoplasm of corpus uteri	0.005	0.995	0.000
H20.8 Other iridocyclitis	0.000	0.995	0.005
G37.9 Demyelinating disease of central nervous system, unspecified	0.005	0.995	0.000
H47.5 Disorders of other visual pathways	0.000	0.995	0.004
N32.0 Bladder-neck obstruction	0.004	0.996	0.000
M94.88 Other specified disorders of cartilage (Other)	0.004	0.996	0.000
M94.8 Other specified disorders of cartilage	0.004	0.996	0.000
M94.86 Other specified disorders of cartilage (Lower leg)	0.004	0.996	0.000
M89.9 Disorder of bone, unspecified	0.004	0.996	0.000
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified	0.004	0.996	0.000
N04 Nephrotic syndrome	0.004	0.996	0.000
K72.0 Acute and subacute hepatic failure	0.004	0.996	0.000
K74.6 Other and unspecified cirrhosis of liver	0.004	0.996	0.000
H20 Iridocyclitis	0.000	0.996	0.004
H20.9 Iridocyclitis, unspecified	0.000	0.996	0.004
M89.94 Disorder of bone, unspecified (Hand)	0.004	0.996	0.000
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system	0.004	0.996	0.000
G70.8 Other specified myoneural disorders	0.000	0.996	0.004
G70.2 Congenital and developmental myasthenia	0.000	0.996	0.004
G70.1 Toxic myoneural disorders	0.000	0.996	0.004
Y51 Drugs primarily affecting the autonomic nervous system	0.000	0.996	0.004
G70.9 Myoneural disorder, unspecified	0.000	0.996	0.004
K74.5 Biliary cirrhosis, unspecified	0.003	0.996	0.000
C54.8 Overlapping lesion of corpus uteri	0.004	0.996	0.000
C54.3 Fundus uteri	0.004	0.996	0.000
C54.2 Myometrium	0.004	0.996	0.000
C54.0 Isthmus uteri	0.004	0.996	0.000
G70-G73 Diseases of myoneural junction and muscle	0.000	0.996	0.004
K76.0 Fatty (change of) liver, not elsewhere classified	0.004	0.996	0.000
M94.89 Other specified disorders of cartilage (Site unspecified)	0.004	0.996	0.000
G37 Other demyelinating diseases of central nervous system	0.004	0.996	0.000
H20.1 Chronic iridocyclitis	0.000	0.996	0.004
G71 Primary disorders of muscles	0.000	0.996	0.004
G72 Other myopathies	0.000	0.996	0.004
G12 Spinal muscular atrophy and related syndromes	0.000	0.996	0.003
H46-H48 Disorders of optic nerve and visual pathways	0.000	0.997	0.003
N04.0 Minor glomerular abnormality	0.003	0.997	0.000
M94.85 Other specified disorders of cartilage (Pelvic region and thigh)	0.003	0.997	0.000
M94.87 Other specified disorders of cartilage (Ankle and foot)	0.003	0.997	0.000
M94.84 Other specified disorders of cartilage (Hand)	0.003	0.997	0.000
M94.83 Other specified disorders of cartilage (Forearm)	0.003	0.997	0.000
M94.82 Other specified disorders of cartilage (Upper arm)	0.003	0.997	0.000
M94.81 Other specified disorders of cartilage (Shoulder region)	0.003	0.997	0.000
M94.80 Other specified disorders of cartilage (Multiple sites)	0.003	0.997	0.000
G71.0 Muscular dystrophy	0.000	0.997	0.003
H20.0 Acute and subacute iridocyclitis	0.000	0.997	0.003
N04.1 Focal and segmental glomerular lesions	0.003	0.997	0.000
C54.9 Corpus uteri, unspecified	0.003	0.997	0.000
G71.3 Mitochondrial myopathy, not elsewhere classified	0.000	0.997	0.003
M89.91 Disorder of bone, unspecified (Shoulder region)	0.003	0.997	0.000
M89.99 Disorder of bone, unspecified (Site unspecified)	0.003	0.997	0.000
M89.93 Disorder of bone, unspecified (Forearm)	0.003	0.997	0.000
M89.90 Disorder of bone, unspecified (Multiple sites)	0.003	0.997	0.000
N04.8 Other	0.003	0.997	0.000
N04.7 Diffuse crescentic glomerulonephritis	0.003	0.997	0.000
N04.6 Dense deposit disease	0.003	0.997	0.000
N04.5 Diffuse mesangiocapillary glomerulonephritis	0.003	0.997	0.000
N04.4 Diffuse endocapillary proliferative glomerulonephritis	0.003	0.997	0.000
N04.3 Diffuse mesangial proliferative glomerulonephritis	0.003	0.997	0.000
N04.2 Diffuse membranous glomerulonephritis	0.003	0.997	0.000
Q23.1 Congenital insufficiency of aortic valve	0.003	0.997	0.000
H20.2 Lens-induced iridocyclitis	0.000	0.997	0.003
M89.92 Disorder of bone, unspecified (Upper arm)	0.003	0.997	0.000
Y51.3 Other parasympatholytics [anticholinergics and antimuscarinics] and spasmolytics, not elsewhere classified	0.000	0.997	0.003
G72.9 Myopathy, unspecified	0.000	0.997	0.003
Y51.6 @-Adrenoreceptor antagonists, not elsewhere classified	0.000	0.997	0.003
G72.8 Other specified myopathies	0.000	0.997	0.003
Y51.9 Other and unspecified drugs primarily affecting the autonomic nervous system	0.000	0.997	0.003
Y51.8 Centrally acting and adrenergic-neuron-blocking agents, not elsewhere classified	0.000	0.997	0.003
Y51.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.000	0.997	0.003
Y51.2 Ganglionic blocking drugs, not elsewhere classified	0.000	0.997	0.003
Y51.1 Other parasympathomimetics [cholinergics]	0.000	0.997	0.003
Y51.0 Anticholinesterase agents	0.000	0.997	0.003
M94 Other disorders of cartilage	0.003	0.997	0.000
G73 Disorders of myoneural junction and muscle in diseases classified elsewhere	0.000	0.997	0.003
S39.9 Unspecified injury of abdomen, lower back and pelvis	0.000	0.997	0.003
H46 Optic neuritis	0.000	0.997	0.003
M94.26 Chondromalacia (Lower leg)	0.003	0.997	0.000
M94.2 Chondromalacia	0.003	0.997	0.000
M89.96 Disorder of bone, unspecified (Lower leg)	0.003	0.997	0.000
M89.95 Disorder of bone, unspecified (Pelvic region and thigh)	0.003	0.997	0.000
G72.0 Drug-induced myopathy	0.000	0.997	0.003
I51.3 Intracardiac thrombosis, not elsewhere classified	0.003	0.997	0.000
F10.0 Acute intoxication	0.003	0.997	0.000
G37.5 Concentric sclerosis [Balo]	0.003	0.997	0.000
G37.4 Subacute necrotising myelitis	0.003	0.997	0.000
G37.2 Central pontine myelinolysis	0.003	0.997	0.000
G37.1 Central demyelination of corpus callosum	0.003	0.997	0.000
G37.0 Diffuse sclerosis	0.003	0.997	0.000
M89 Other disorders of bone	0.003	0.997	0.000
G71.9 Primary disorder of muscle, unspecified	0.000	0.997	0.003
G71.8 Other primary disorders of muscles	0.000	0.997	0.003
G71.2 Congenital myopathies	0.000	0.997	0.003
G72.4 Inflammatory myopathy, not elsewhere classified	0.000	0.997	0.003
G72.3 Periodic paralysis	0.000	0.997	0.003
G72.2 Myopathy due to other toxic agents	0.000	0.997	0.003
G72.1 Alcoholic myopathy	0.000	0.997	0.003
K72.9 Hepatic failure, unspecified	0.003	0.997	0.000
G12.9 Spinal muscular atrophy, unspecified	0.000	0.997	0.003
G12.8 Other spinal muscular atrophies and related syndromes	0.000	0.997	0.003
G12.1 Other inherited spinal muscular atrophy	0.000	0.997	0.003
G12.0 Infantile spinal muscular atrophy, type I [Werdnig-Hoffman]	0.000	0.997	0.003
G37.8 Other specified demyelinating diseases of central nervous system	0.003	0.997	0.000
H48 Disorders of optic [2nd] nerve and visual pathways in diseases classified elsewhere	0.000	0.997	0.003
M89.3 Hypertrophy of bone	0.003	0.997	0.000
U80.8 Agent resistant to other penicillin-related antibiotic	0.003	0.997	0.000
Y51.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.000	0.997	0.002
M89.98 Disorder of bone, unspecified (Other)	0.003	0.997	0.000
N95.8 Other specified menopausal and perimenopausal disorders	0.000	0.997	0.003
M89.0 Algoneurodystrophy	0.003	0.997	0.000
N13.5 Kinking and stricture of ureter without hydronephrosis	0.000	0.997	0.003
M89.37 Hypertrophy of bone (Ankle and foot)	0.003	0.997	0.000
Z74.0 Reduced mobility	0.000	0.997	0.003
G71.1 Myotonic disorders	0.000	0.997	0.002
M89.4 Other hypertrophic osteo-arthropathy	0.002	0.997	0.000
U80.1 Methicillin resistant agent	0.003	0.997	0.000
M89.04 Algoneurodystrophy (Hand)	0.002	0.997	0.000
M94.3 Chondrolysis	0.002	0.998	0.000
M94.1 Relapsing polychondritis	0.002	0.998	0.000
M94.0 Chondrocostal junction syndrome [Tietze]	0.002	0.998	0.000
H57 Other disorders of eye and adnexa	0.000	0.998	0.002
F10.4 Withdrawal state with delirium	0.002	0.998	0.000
G73.7 Myopathy other diseases classified elsewhere	0.000	0.998	0.002
G73.6 Myopathy in metabolic diseases	0.000	0.998	0.002
G73.5 Myopathy in endocrine diseases	0.000	0.998	0.002
G73.4 Myopathy in infectious and parasitic diseases classified elsewhere	0.000	0.998	0.002
G73.3 Myasthenic syndromes in other diseases classified elsewhere	0.000	0.998	0.002
G73.2 Other myasthenic syndromes in neoplastic disease	0.000	0.998	0.002
G73.1 Eaton-Lambert syndrome	0.000	0.998	0.002
G73.0 Myasthenic syndromes in endocrine diseases	0.000	0.998	0.002
M94.29 Chondromalacia (Site unspecified)	0.002	0.998	0.000
M94.28 Chondromalacia (Other)	0.002	0.998	0.000
M94.27 Chondromalacia (Ankle and foot)	0.002	0.998	0.000
M94.25 Chondromalacia (Pelvic region and thigh)	0.002	0.998	0.000
M94.24 Chondromalacia (Hand)	0.002	0.998	0.000
M94.23 Chondromalacia (Forearm)	0.002	0.998	0.000
M94.22 Chondromalacia (Upper arm)	0.002	0.998	0.000
M94.21 Chondromalacia (Shoulder region)	0.002	0.998	0.000
M94.20 Chondromalacia (Multiple sites)	0.002	0.998	0.000
R16.0 Hepatomegaly, not elsewhere classified	0.002	0.998	0.000
M25.77 Osteophyte (Ankle and foot)	0.000	0.998	0.002
M89.6 Osteopathy after poliomyelitis	0.002	0.998	0.000
M89.2 Other disorders of bone development and growth	0.002	0.998	0.000
M89.1 Epiphyseal arrest	0.002	0.998	0.000
T86 Failure and rejection of transplanted organs and tissues	0.002	0.998	0.000
M89.38 Hypertrophy of bone (Other)	0.002	0.998	0.000
M94.9 Disorder of cartilage, unspecified	0.002	0.998	0.000
S20.8 Superficial injuries of other and unspecified parts of thorax	0.000	0.998	0.002
N76.8 Other specified inflammation of vagina and vulva	0.002	0.998	0.000
M89.5 Osteolysis	0.002	0.998	0.000
M75.3 Calcific tendinitis of shoulder	0.000	0.998	0.002
M89.09 Algoneurodystrophy (Site unspecified)	0.002	0.998	0.000
L57.4 Cutis laxa senilis	0.002	0.998	0.000
U80 Agent resistant to penicillin and related antibiotics	0.002	0.998	0.000
H48.8 Other disorders of optic nerve and visual pathways in diseases classified elsewhere	0.000	0.998	0.002
H48.1 Retrobulbar neuritis in diseases classified elsewhere	0.000	0.998	0.002
H48.0 Optic atrophy in diseases classified elsewhere	0.000	0.998	0.002
M89.39 Hypertrophy of bone (Site unspecified)	0.002	0.998	0.000
M89.36 Hypertrophy of bone (Lower leg)	0.002	0.998	0.000
M89.35 Hypertrophy of bone (Pelvic region and thigh)	0.002	0.998	0.000
M89.34 Hypertrophy of bone (Hand)	0.002	0.998	0.000
M89.33 Hypertrophy of bone (Forearm)	0.002	0.998	0.000
M89.32 Hypertrophy of bone (Upper arm)	0.002	0.998	0.000
M89.31 Hypertrophy of bone (Shoulder region)	0.002	0.998	0.000
M89.30 Hypertrophy of bone (Multiple sites)	0.002	0.998	0.000
M89.40 Other hypertrophic osteoarthropathy (Multiple sites)	0.002	0.998	0.000
F10.2 Dependence syndrome	0.002	0.998	0.000
R16.2 Hepatomegaly with splenomegaly, not elsewhere classified	0.002	0.998	0.000
T91.8 Sequelae of other specified injuries of neck and trunk	0.002	0.998	0.000
M80-M85 Disorders of bone density and structure	0.000	0.998	0.002
F10.6 Amnesic syndrome	0.002	0.998	0.000
K74.3 Primary biliary cirrhosis	0.001	0.998	0.001
M89.03 Algoneurodystrophy (Forearm)	0.002	0.998	0.000
T91.1 Sequelae of fracture of spine	0.002	0.998	0.000
G11.9 Hereditary ataxia, unspecified	0.000	0.998	0.002
G11 Hereditary ataxia	0.000	0.998	0.002
M89.08 Algoneurodystrophy (Other)	0.002	0.998	0.000
M89.05 Algoneurodystrophy (Pelvic region and thigh)	0.002	0.998	0.000
M89.02 Algoneurodystrophy (Upper arm)	0.002	0.998	0.000
M89.01 Algoneurodystrophy (Shoulder region)	0.002	0.998	0.000
M89.00 Algoneurodystrophy (Multiple sites)	0.002	0.998	0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.000	0.998	0.002
J98.1 Pulmonary collapse	0.002	0.998	0.000
M89.06 Algoneurodystrophy (Lower leg)	0.002	0.998	0.000
S22.30 Fracture of rib (closed)	0.000	0.998	0.002
H10.9 Conjunctivitis, unspecified	0.002	0.998	0.000
H57.0 Anomalies of pupillary function	0.000	0.998	0.002
R72 Abnormality of white blood cells, not elsewhere classified	0.000	0.998	0.002
M89.49 Other hypertrophic osteoarthropathy (Site unspecified)	0.002	0.998	0.000
M89.48 Other hypertrophic osteoarthropathy (Other)	0.002	0.998	0.000
M89.47 Other hypertrophic osteoarthropathy (Ankle and foot)	0.002	0.998	0.000
M89.46 Other hypertrophic osteoarthropathy (Lower leg)	0.002	0.998	0.000
M89.45 Other hypertrophic osteoarthropathy (Pelvic region and thigh)	0.002	0.998	0.000
M89.44 Other hypertrophic osteoarthropathy (Hand)	0.002	0.998	0.000
M89.43 Other hypertrophic osteoarthropathy (Forearm)	0.002	0.998	0.000
M89.42 Other hypertrophic osteoarthropathy (Upper arm)	0.002	0.998	0.000
M89.41 Other hypertrophic osteoarthropathy (Shoulder region)	0.002	0.998	0.000
Z43.2 Attention to ileostomy	0.000	0.998	0.002
M25.71 Osteophyte (Shoulder region)	0.000	0.998	0.002
M94.09 Chondrocostal junction syndrome [Tietze]-Site unspec	0.002	0.998	0.000
M94.08 Chondrocostal junction syndrome [Tietze]-Other	0.002	0.998	0.000
M94.07 Chondrocostal junction syndrome [Tietze]-Ankle/foot	0.002	0.998	0.000
M94.06 Chondrocostal junction syndrome [Tietze]-Lower leg	0.002	0.998	0.000
M94.05 Chondrocostal junction syndrome [Tietze]-Pelvic/thigh	0.002	0.998	0.000
M94.04 Chondrocostal junction syndrome [Tietze]-Hand	0.002	0.998	0.000
M94.03 Chondrocostal junction syndrome [Tietze]-Forearm	0.002	0.998	0.000
M94.02 Chondrocostal junction syndrome [Tietze]-Upper arm	0.002	0.998	0.000
M94.01 Chondrocostal junction syndrome [Tietze]-Shldr region	0.002	0.998	0.000
M94.00 Chondrocostal junction syndrome [Tietze]-Mult sites	0.002	0.998	0.000
M94.19 Relapsing polychondritis (Site unspecified)	0.002	0.998	0.000
M94.18 Relapsing polychondritis (Other)	0.002	0.998	0.000
M94.17 Relapsing polychondritis (Ankle and foot)	0.002	0.998	0.000
M94.16 Relapsing polychondritis (Lower leg)	0.002	0.998	0.000
M94.15 Relapsing polychondritis (Pelvic region and thigh)	0.002	0.998	0.000
M94.14 Relapsing polychondritis (Hand)	0.002	0.998	0.000
M94.13 Relapsing polychondritis (Forearm)	0.002	0.998	0.000
M94.12 Relapsing polychondritis (Upper arm)	0.002	0.998	0.000
M94.11 Relapsing polychondritis (Shoulder region)	0.002	0.998	0.000
M94.10 Relapsing polychondritis (Multiple sites)	0.002	0.998	0.000
M94.39 Chondrolysis (Site unspecified)	0.002	0.998	0.000
M94.38 Chondrolysis (Other)	0.002	0.998	0.000
M94.37 Chondrolysis (Ankle and foot)	0.002	0.998	0.000
M94.36 Chondrolysis (Lower leg)	0.002	0.998	0.000
M94.35 Chondrolysis (Pelvic region and thigh)	0.002	0.998	0.000
M94.34 Chondrolysis (Hand)	0.002	0.998	0.000
M94.33 Chondrolysis (Forearm)	0.002	0.998	0.000
M94.32 Chondrolysis (Upper arm)	0.002	0.998	0.000
M94.31 Chondrolysis (Shoulder region)	0.002	0.998	0.000
M94.30 Chondrolysis (Multiple sites)	0.002	0.998	0.000
L30.8 Other specified dermatitis	0.000	0.998	0.002
T17.2 Foreign body in pharynx	0.000	0.998	0.002
T91 Sequelae of injuries of neck and trunk	0.002	0.998	0.000
T91.9 Sequelae of unspecified injury of neck and trunk	0.002	0.998	0.000
F10 Mental and behavioural disorders due to use of alcohol	0.002	0.998	0.000
B37.8 Candidiasis of other sites	0.002	0.998	0.000
M89.19 Epiphyseal arrest (Site unspecified)	0.002	0.998	0.000
M89.18 Epiphyseal arrest (Other)	0.002	0.998	0.000
M89.17 Epiphyseal arrest (Ankle and foot)	0.002	0.998	0.000
M89.16 Epiphyseal arrest (Lower leg)	0.002	0.998	0.000
M89.15 Epiphyseal arrest (Pelvic region and thigh)	0.002	0.998	0.000
M89.14 Epiphyseal arrest (Hand)	0.002	0.998	0.000
M89.13 Epiphyseal arrest (Forearm)	0.002	0.998	0.000
M89.12 Epiphyseal arrest (Upper arm)	0.002	0.998	0.000
M89.11 Epiphyseal arrest (Shoulder region)	0.002	0.998	0.000
M89.10 Epiphyseal arrest (Multiple sites)	0.002	0.998	0.000
M89.29 Other disorders of bone development and growth (Site unspecified)	0.002	0.998	0.000
M89.28 Other disorders of bone development and growth (Other)	0.002	0.998	0.000
M89.27 Other disorders of bone development and growth (Ankle and foot)	0.002	0.998	0.000
M89.26 Other disorders of bone development and growth (Lower leg)	0.002	0.998	0.000
M89.25 Other disorders of bone development and growth (Pelvic region and thigh)	0.002	0.998	0.000
M89.24 Other disorders of bone development and growth (Hand)	0.002	0.998	0.000
M89.23 Other disorders of bone development and growth (Forearm)	0.002	0.998	0.000
M89.22 Other disorders of bone development and growth (Upper arm)	0.002	0.998	0.000
M89.21 Other disorders of bone development and growth (Shoulder region)	0.002	0.998	0.000
M89.20 Other disorders of bone development and growth (Multiple sites)	0.002	0.998	0.000
M89.69 Osteopathy after poliomyelitis (Site unspecified)	0.002	0.998	0.000
M89.68 Osteopathy after poliomyelitis (Other)	0.002	0.998	0.000
M89.67 Osteopathy after poliomyelitis (Ankle and foot)	0.002	0.998	0.000
M89.66 Osteopathy after poliomyelitis (Lower leg)	0.002	0.998	0.000
M89.65 Osteopathy after poliomyelitis (Pelvic region and thigh)	0.002	0.998	0.000
M89.64 Osteopathy after poliomyelitis (Hand)	0.002	0.998	0.000
M89.63 Osteopathy after poliomyelitis (Forearm)	0.002	0.998	0.000
M89.62 Osteopathy after poliomyelitis (Upper arm)	0.002	0.998	0.000
M89.61 Osteopathy after poliomyelitis (Shoulder region)	0.002	0.998	0.000
M89.60 Osteopathy after poliomyelitis (Multiple sites)	0.002	0.998	0.000
G62.9 Polyneuropathy, unspecified	0.002	0.998	0.000
T86.9 Failure and rejection of unspecified transplanted organ and tissue	0.002	0.998	0.000
T86.3 Heart-lung transplant failure and rejection	0.002	0.998	0.000
T86.2 Heart transplant failure and rejection	0.002	0.998	0.000
M82 Osteoporosis in diseases classified elsewhere	0.000	0.998	0.002
M94.99 Disorder of cartilage, unspecified (Site unspecified)	0.002	0.998	0.000
M94.98 Disorder of cartilage, unspecified (Other)	0.002	0.998	0.000
M94.97 Disorder of cartilage, unspecified (Ankle and foot)	0.002	0.998	0.000
M94.95 Disorder of cartilage, unspecified (Pelvic region and thigh)	0.002	0.998	0.000
M94.94 Disorder of cartilage, unspecified (Hand)	0.002	0.998	0.000
M94.93 Disorder of cartilage, unspecified (Forearm)	0.002	0.998	0.000
M94.92 Disorder of cartilage, unspecified (Upper arm)	0.002	0.998	0.000
M94.91 Disorder of cartilage, unspecified (Shoulder region)	0.002	0.998	0.000
M94.90 Disorder of cartilage, unspecified (Multiple sites)	0.002	0.998	0.000
M89.07 Algoneurodystrophy (Ankle and foot)	0.002	0.998	0.000
M89.59 Osteolysis (Site unspecified)	0.002	0.998	0.000
M89.58 Osteolysis (Other)	0.002	0.998	0.000
M89.57 Osteolysis (Ankle and foot)	0.002	0.998	0.000
M89.56 Osteolysis (Lower leg)	0.002	0.998	0.000
M89.54 Osteolysis (Hand)	0.002	0.998	0.000
M89.53 Osteolysis (Forearm)	0.002	0.998	0.000
M89.52 Osteolysis (Upper arm)	0.002	0.998	0.000
M89.51 Osteolysis (Shoulder region)	0.002	0.998	0.000
M89.50 Osteolysis (Multiple sites)	0.002	0.998	0.000
M35.1 Other overlap syndromes	0.000	0.998	0.002
T86.4 Liver transplant failure and rejection	0.002	0.998	0.000
H57.9 Disorder of eye and adnexa, unspecified	0.000	0.998	0.002
T91.2 Sequelae of other fracture of thorax and pelvis	0.002	0.998	0.000
W21.9 Unspecified place	0.000	0.998	0.002
G11.4 Hereditary spastic paraplegia	0.000	0.998	0.002
M83 Adult osteomalacia	0.000	0.998	0.002
M89.55 Osteolysis (Pelvic region and thigh)	0.002	0.998	0.000
G10 Huntington's disease	0.000	0.998	0.002
K00.9 Disorder of tooth development, unspecified	0.002	0.998	0.000
M89.8 Other specified disorders of bone	0.002	0.998	0.000
G11.8 Other hereditary ataxias	0.000	0.998	0.002
G11.3 Cerebellar ataxia with defective DNA repair	0.000	0.998	0.002
G11.2 Late-onset cerebellar ataxia	0.000	0.998	0.002
G11.1 Early-onset cerebellar ataxia	0.000	0.998	0.002
G11.0 Congenital nonprogressive ataxia	0.000	0.998	0.002
G13 Systemic atrophies primarily affecting central nervous system in diseases classified elsewhere	0.000	0.998	0.002
M82.11 Osteoporosis in endocrine disorders (Shoulder region)	0.000	0.998	0.002
M94.96 Disorder of cartilage, unspecified (Lower leg)	0.002	0.998	0.000
L57.0 Actinic keratosis	0.002	0.998	0.000
E78.5 Hyperlipidaemia, unspecified	0.002	0.998	0.000
M82.1 Osteoporosis in endocrine disorders	0.000	0.998	0.002
G14 Postpolio syndrome	0.000	0.998	0.002
S06.00 Concussion (without open intracranial wound)	0.000	0.998	0.002
T91.5 Sequelae of injury of intra-abdominal and pelvic organs	0.002	0.998	0.000
T91.4 Sequelae of injury of intrathoracic organs	0.002	0.998	0.000
T91.0 Sequelae of superficial injury and open wound of neck and trunk	0.002	0.998	0.000
R16 Hepatomegaly and splenomegaly, not elsewhere classified	0.002	0.998	0.000
M89.89 Other specified disorders of bone (Site unspecified)	0.002	0.998	0.000
F10.8 Other mental and behavioural disorders	0.002	0.998	0.000
F10.5 Psychotic disorder	0.002	0.998	0.000
F10.7 Residual and late-onset psychotic disorder	0.002	0.998	0.000
U80.0 Penicillin resistant agent	0.002	0.998	0.000
D68.5 Primary Thrombophilia	0.000	0.998	0.002

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations