TreeWAS – Variant ID: rs545833

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Click here to show this figure without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
D68.2 Hereditary deficiency of other clotting factors	0.970	0.030	0.000
D68 Other coagulation defects	0.943	0.057	0.000
D68.5 Primary Thrombophilia	0.900	0.100	0.000
D68.3 Haemorrhagic disorder due to circulating anticoagulants	0.878	0.122	0.000
D68.1 Hereditary factor XI deficiency	0.751	0.249	0.000
D68.6 Other Thrombophilia	0.706	0.294	0.000
D68.9 Coagulation defect, unspecified	0.694	0.306	0.000
D68.0 Von Willebrand's disease	0.691	0.309	0.000
D68.8 Other specified coagulation defects	0.660	0.340	0.000
D68.4 Acquired coagulation factor deficiency	0.632	0.368	0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.238	0.762	0.000
D66 Hereditary factor VIII deficiency	0.181	0.819	0.000
D67 Hereditary factor IX deficiency	0.171	0.829	0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]	0.148	0.851	0.000
E04.9 Non-toxic goitre, unspecified	0.000	0.881	0.119
D69 Purpura and other haemorrhagic conditions	0.106	0.894	0.000
E89.0 Postprocedural hypothyroidism	0.000	0.903	0.097
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified	0.000	0.904	0.096
D69.2 Other nonthrombocytopenic purpura	0.091	0.909	0.000
E04 Other non-toxic goitre	0.000	0.912	0.088
D69.0 Allergic purpura	0.087	0.913	0.000
E83.5 Disorders of calcium metabolism	0.000	0.914	0.086
E89.3 Postprocedural hypopituitarism	0.000	0.914	0.086
E70-E90 Metabolic disorders	0.000	0.917	0.083
E85 Amyloidosis	0.000	0.917	0.083
E83 Disorders of mineral metabolism	0.000	0.918	0.082
E89.6 Postprocedural adrenocortical(-medullary) hypofunction	0.000	0.919	0.080
E85.4 Organ-limited amyloidosis	0.000	0.920	0.080
D69.9 Haemorrhagic condition, unspecified	0.079	0.921	0.000
D69.8 Other specified haemorrhagic conditions	0.076	0.924	0.000
D69.1 Qualitative platelet defects	0.076	0.924	0.000
E89.2 Postprocedural hypoparathyroidism	0.000	0.924	0.076
D69.4 Other primary thrombocytopenia	0.074	0.926	0.000
E89.4 Postprocedural ovarian failure	0.000	0.928	0.072
E00-E07 Disorders of thyroid gland	0.000	0.929	0.071
E83.3 Disorders of phosphorus metabolism	0.000	0.930	0.070
E85.9 Amyloidosis, unspecified	0.000	0.930	0.070
E89.9 Postprocedural endocrine and metabolic disorder, unspecified	0.000	0.931	0.069
E89.8 Other postprocedural endocrine and metabolic disorders	0.000	0.931	0.069
E89.5 Postprocedural testicular hypofunction	0.000	0.931	0.069
E89.1 Postprocedural hypoinsulinaemia	0.000	0.931	0.069
D69.5 Secondary thrombocytopenia	0.065	0.935	0.000
E05 Thyrotoxicosis [hyperthyroidism]	0.000	0.935	0.065
Chapter IV Endocrine, nutritional and metabolic diseases	0.000	0.935	0.065
E04.1 Non-toxic single thyroid nodule	0.000	0.935	0.065
E04.8 Other specified non-toxic goitre	0.000	0.937	0.063
E73 Lactose intolerance	0.000	0.937	0.063
E85.3 Secondary systemic amyloidosis	0.000	0.937	0.063
E80 Disorders of porphyrin and bilirubin metabolism	0.000	0.938	0.062
E88 Other metabolic disorders	0.000	0.939	0.061
E04.0 Non-toxic diffuse goitre	0.000	0.939	0.061
E84 Cystic fibrosis	0.000	0.940	0.060
E77 Disorders of glycoprotein metabolism	0.000	0.940	0.060
E76 Disorders of glycosaminoglycan metabolism	0.000	0.940	0.060
E72 Other disorders of amino-acid metabolism	0.000	0.940	0.060
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.000	0.940	0.060
E70 Disorders of aromatic amino-acid metabolism	0.000	0.940	0.060
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.000	0.940	0.060
E85.8 Other amyloidosis	0.000	0.941	0.059
E85.2 Heredofamilial amyloidosis, unspecified	0.000	0.941	0.059
E85.1 Neuropathic heredofamilial amyloidosis	0.000	0.941	0.059
E85.0 Nonneuropathic heredofamilial amyloidosis	0.000	0.941	0.059
E05.2 Thyrotoxicosis with toxic multinodular goitre	0.000	0.941	0.059
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.000	0.941	0.059
E83.9 Disorder of mineral metabolism, unspecified	0.000	0.941	0.059
E83.8 Other disorders of mineral metabolism	0.000	0.941	0.059
E83.2 Disorders of zinc metabolism	0.000	0.941	0.059
E83.0 Disorders of copper metabolism	0.000	0.941	0.059
E79 Disorders of purine and pyrimidine metabolism	0.000	0.942	0.058
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.000	0.942	0.058
E74 Other disorders of carbohydrate metabolism	0.000	0.943	0.057
E04.2 Non-toxic multinodular goitre	0.000	0.944	0.056
E16 Other disorders of pancreatic internal secretion	0.000	0.945	0.055
E16.0 Drug-induced hypoglycaemia without coma	0.000	0.947	0.053
M19.97 Arthrosis, unspecified (Ankle and foot)	0.053	0.947	0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.948	0.051
E00 Congenital iodine-deficiency syndrome	0.000	0.948	0.051
E02 Subclinical iodine-deficiency hypothyroidism	0.000	0.949	0.051
E80.4 Gilbert's syndrome	0.000	0.950	0.050
E05.0 Thyrotoxicosis with diffuse goitre	0.000	0.951	0.049
E73.9 Lactose intolerance, unspecified	0.000	0.951	0.049
E05.9 Thyrotoxicosis, unspecified	0.000	0.951	0.049
E88.8 Other specified metabolic disorders	0.000	0.953	0.047
E05.5 Thyroid crisis or storm	0.000	0.953	0.047
E05.4 Thyrotoxicosis factitia	0.000	0.953	0.047
E05.3 Thyrotoxicosis from ectopic thyroid tissue	0.000	0.953	0.047
E05.1 Thyrotoxicosis with toxic single thyroid nodule	0.000	0.953	0.047
E88.3 Tumour lysis syndrome	0.000	0.954	0.046
E05.8 Other thyrotoxicosis	0.000	0.954	0.046
E73.8 Other lactose intolerance	0.000	0.954	0.046
E73.1 Secondary lactase deficiency	0.000	0.954	0.046
E73.0 Congenital lactase deficiency	0.000	0.954	0.046
E80.2 Other porphyria	0.000	0.955	0.045
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified	0.000	0.955	0.045
E80.7 Disorder of bilirubin metabolism, unspecified	0.000	0.955	0.045
E80.5 Crigler-Najjar syndrome	0.000	0.955	0.045
E80.3 Defects of catalase and peroxydase	0.000	0.955	0.045
E80.0 Hereditary erythropoietic porphyria	0.000	0.955	0.045
E88.1 Lipodystrophy, not elsewhere classified	0.000	0.956	0.044
E80.6 Other disorders of bilirubin metabolism	0.000	0.957	0.043
E70.9 Disorder of aromatic amino-acid metabolism, unspecified	0.000	0.957	0.043
E70.8 Other disorders of aromatic amino-acid metabolism	0.000	0.957	0.043
E70.3 Albinism	0.000	0.957	0.043
E70.2 Disorders of tyrosine metabolism	0.000	0.957	0.043
E70.1 Other hyperphenylalaninaemias	0.000	0.957	0.043
E70.0 Classical phenylketonuria	0.000	0.957	0.043
E71.3 Disorders of fatty-acid metabolism	0.000	0.957	0.043
E71.2 Disorder of branched-chain amino-acid metabolism, unspecified	0.000	0.957	0.043
E71.1 Other disorders of branched-chain amino-acid metabolism	0.000	0.957	0.043
E71.0 Maple-syrup-urine disease	0.000	0.957	0.043
E72.9 Disorder of amino-acid metabolism, unspecified	0.000	0.957	0.043
E72.8 Other specified disorders of amino-acid metabolism	0.000	0.957	0.043
E72.5 Disorders of glycine metabolism	0.000	0.957	0.043
E72.4 Disorders of ornithine metabolism	0.000	0.957	0.043
E72.3 Disorders of lysine and hydroxylysine metabolism	0.000	0.957	0.043
E72.2 Disorders of urea cycle metabolism	0.000	0.957	0.043
E72.1 Disorders of sulphur-bearing amino-acid metabolism	0.000	0.957	0.043
E72.0 Disorders of amino-acid transport	0.000	0.957	0.043
E76.9 Disorder of glucosaminoglycan metabolism, unspecified	0.000	0.957	0.043
E76.8 Other disorders of glucosaminoglycan metabolism	0.000	0.957	0.043
E76.3 Mucopolysaccharidosis, unspecified	0.000	0.957	0.043
E76.2 Other mucopolysaccharidoses	0.000	0.957	0.043
E76.1 Mucopolysaccharidosis, type II	0.000	0.957	0.043
E76.0 Mucopolysaccharidosis, type I	0.000	0.957	0.043
E77.9 Disorder of glycoprotein metabolism, unspecified	0.000	0.957	0.043
E77.8 Other disorders of glycoprotein metabolism	0.000	0.957	0.043
E77.1 Defects in glycoprotein degradation	0.000	0.957	0.043
E77.0 Defects in posttranslational modification of lysosomal enzymes	0.000	0.957	0.043
E84.9 Cystic fibrosis, unspecified	0.000	0.957	0.043
E84.8 Cystic fibrosis with other manifestations	0.000	0.957	0.043
E84.1 Cystic fibrosis with intestinal manifestations	0.000	0.957	0.043
E84.0 Cystic fibrosis with pulmonary manifestations	0.000	0.957	0.043
E80.1 Porphyria cutanea tarda	0.000	0.957	0.043
E07 Other disorders of thyroid	0.000	0.957	0.043
E15 Nondiabetic hypoglycaemic coma	0.000	0.957	0.042
E88.9 Metabolic disorder, unspecified	0.000	0.957	0.042
E40-E46 Malnutrition	0.000	0.958	0.042
E79.9 Disorder of purine and pyrimidine metabolism, unspecified	0.000	0.958	0.041
E79.8 Other disorders of purine and pyrimidine metabolism	0.000	0.958	0.041
E79.1 Lesch-Nyhan syndrome	0.000	0.958	0.041
E75.6 Lipid storage disorder, unspecified	0.000	0.958	0.041
E75.4 Neuronal ceroid lipofuscinosis	0.000	0.958	0.041
E75.3 Sphingolipidosis, unspecified	0.000	0.958	0.041
E75.2 Other sphingolipidosis	0.000	0.958	0.041
E75.1 Other gangliosidosis	0.000	0.958	0.041
E75.0 GM2 gangliosidosis	0.000	0.958	0.041
E03 Other hypothyroidism	0.000	0.959	0.041
E16.2 Hypoglycaemia, unspecified	0.000	0.959	0.041
E74.9 Disorder of carbohydrate metabolism, unspecified	0.000	0.959	0.041
E74.8 Other specified disorders of carbohydrate metabolism	0.000	0.959	0.041
E74.4 Disorders of pyruvate metabolism and gluconeogenesis	0.000	0.959	0.041
E74.2 Disorders of galactose metabolism	0.000	0.959	0.041
E74.1 Disorders of fructose metabolism	0.000	0.959	0.041
E74.0 Glycogen storage disease	0.000	0.959	0.041
E88.2 Lipomatosis, not elsewhere classified	0.000	0.959	0.041
E16.9 Disorder of pancreatic internal secretion, unspecified	0.000	0.960	0.040
E16.8 Other specified disorders of pancreatic internal secretion	0.000	0.960	0.040
E16.4 Abnormal secretion of gastrin	0.000	0.960	0.040
E16.3 Increased secretion of glucagon	0.000	0.960	0.040
D69.3 Idiopathic thrombocytopenic purpura	0.040	0.960	0.000
E79.0 Hyperuricaemia without signs of inflammatory arthritis and tophaceous disease	0.000	0.961	0.039
E75.5 Other lipid storage disorders	0.000	0.961	0.039
E83.4 Disorders of magnesium metabolism	0.000	0.961	0.039
E29.1 Testicular hypofunction	0.000	0.961	0.039
E74.3 Other disorders of intestinal carbohydrate absorption	0.000	0.962	0.038
E29 Testicular dysfunction	0.000	0.962	0.038
E20-E35 Disorders of other endocrine glands	0.000	0.962	0.038
E00.9 Congenital iodine-deficiency syndrome, unspecified	0.000	0.963	0.037
E00.2 Congenital iodine-deficiency syndrome, mixed type	0.000	0.963	0.037
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type	0.000	0.963	0.037
E00.0 Congenital iodine-deficiency syndrome, neurological type	0.000	0.963	0.037
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions	0.000	0.963	0.037
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified	0.000	0.963	0.037
E01.1 Iodine-deficiency-related multinodular (endemic) goitre	0.000	0.963	0.037
E01.0 Iodine-deficiency-related diffuse (endemic) goitre	0.000	0.963	0.037
E16.1 Other hypoglycaemia	0.000	0.965	0.035
E07.8 Other specified disorders of thyroid	0.000	0.965	0.035
E03.8 Other specified hypothyroidism	0.000	0.968	0.032
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.000	0.969	0.031
E07.1 Dyshormogenetic goitre	0.000	0.969	0.031
E07.0 Hypersecretion of calcitonin	0.000	0.969	0.031
E44 Protein-energy malnutrition of moderate and mild degree	0.000	0.970	0.030
E45 Retarded development following protein-energy malnutrition	0.000	0.970	0.030
E43 Unspecified severe protein-energy malnutrition	0.000	0.970	0.030
E42 Marasmic kwashiorkor	0.000	0.970	0.030
E41 Nutritional marasmus	0.000	0.970	0.030
E40 Kwashiorkor	0.000	0.970	0.030
E03.5 Myxoedema coma	0.000	0.970	0.030
E03.4 Atrophy of thyroid (acquired)	0.000	0.970	0.030
E03.3 Postinfectious hypothyroidism	0.000	0.970	0.030
E03.1 Congenital hypothyroidism without goitre	0.000	0.970	0.030
E03.0 Congenital hypothyroidism with diffuse goitre	0.000	0.970	0.030
E50-E64 Other nutritional deficiencies	0.000	0.970	0.030
E28 Ovarian dysfunction	0.000	0.971	0.029
E26 Hyperaldosteronism	0.000	0.972	0.028
E65-E68 Obesity and other hyperalimentation	0.000	0.972	0.028
E29.9 Testicular dysfunction, unspecified	0.000	0.973	0.027
E29.8 Other testicular dysfunction	0.000	0.973	0.027
E29.0 Testicular hyperfunction	0.000	0.973	0.027
E35 Disorders of endocrine glands in diseases classified elsewhere	0.000	0.973	0.027
E32 Diseases of thymus	0.000	0.973	0.027
E31 Polyglandular dysfunction	0.000	0.973	0.027
E30 Disorders of puberty, not elsewhere classified	0.000	0.973	0.027
E25 Adrenogenital disorders	0.000	0.973	0.027
E06 Thyroiditis	0.000	0.973	0.026
E20 Hypoparathyroidism	0.000	0.974	0.026
E34 Other endocrine disorders	0.000	0.975	0.025
E46 Unspecified protein-energy malnutrition	0.000	0.975	0.025
E24 Cushing's syndrome	0.000	0.976	0.024
E28.2 Polycystic ovarian syndrome	0.000	0.977	0.023
E55 Vitamin D deficiency	0.000	0.978	0.022
E44.1 Mild protein-energy malnutrition	0.000	0.978	0.022
E44.0 Moderate protein-energy malnutrition	0.000	0.978	0.022
E26.0 Primary hyperaldosteronism	0.000	0.978	0.022
E64 Sequelae of malnutrition and other nutritional deficiencies	0.000	0.978	0.022
E63 Other nutritional deficiencies	0.000	0.978	0.022
E56 Other vitamin deficiencies	0.000	0.978	0.022
E51 Thiamine deficiency	0.000	0.978	0.022
E50 Vitamin A deficiency	0.000	0.978	0.022
E60 Dietary zinc deficiency	0.000	0.978	0.022
E59 Dietary selenium deficiency	0.000	0.978	0.022
E54 Ascorbic acid deficiency	0.000	0.978	0.022
E52 Niacin deficiency [pellagra]	0.000	0.978	0.022
E27 Other disorders of adrenal gland	0.000	0.978	0.022
E58 Dietary calcium deficiency	0.000	0.979	0.021
E28.9 Ovarian dysfunction, unspecified	0.000	0.979	0.021
E28.8 Other ovarian dysfunction	0.000	0.979	0.021
E28.1 Androgen excess	0.000	0.979	0.021
E28.0 Oestrogen excess	0.000	0.979	0.021
E28.3 Primary ovarian failure	0.000	0.979	0.021
E26.8 Other hyperaldosteronism	0.000	0.980	0.020
E26.1 Secondary hyperaldosteronism	0.000	0.980	0.020
E67 Other hyperalimentation	0.000	0.980	0.020
E68 Sequelae of hyperalimentation	0.000	0.980	0.020
E34.0 Carcinoid syndrome	0.000	0.980	0.020
E25.9 Adrenogenital disorder, unspecified	0.000	0.980	0.020
E25.8 Other adrenogenital disorders	0.000	0.980	0.020
E25.0 Congenital adrenogenital disorders associated with enzyme deficiency	0.000	0.980	0.020
E30.9 Disorder of puberty, unspecified	0.000	0.980	0.020
E30.8 Other disorders of puberty	0.000	0.980	0.020
E30.1 Precocious puberty	0.000	0.980	0.020
E30.0 Delayed puberty	0.000	0.980	0.020
E31.9 Polyglandular dysfunction, unspecified	0.000	0.980	0.020
E31.8 Other polyglandular dysfunction	0.000	0.980	0.020
E31.1 Polyglandular hyperfunction	0.000	0.980	0.020
E31.0 Autoimmune polyglandular failure	0.000	0.980	0.020
E32.9 Disease of thymus, unspecified	0.000	0.980	0.020
E32.8 Other diseases of thymus	0.000	0.980	0.020
E32.1 Abscess of thymus	0.000	0.980	0.020
E32.0 Persistent hyperplasia of thymus	0.000	0.980	0.020
E35.8 Disorders of other endocrine glands in diseases classified elsewhere	0.000	0.980	0.020
E35.1 Disorders of adrenal glands in diseases classified elsewhere	0.000	0.980	0.020
E35.0 Disorders of thyroid gland in diseases classified elsewhere	0.000	0.980	0.020
E22 Hyperfunction of pituitary gland	0.000	0.980	0.020
E61 Deficiency of other nutrient elements	0.000	0.980	0.020
E26.9 Hyperaldosteronism, unspecified	0.000	0.980	0.019
E06.5 Other chronic thyroiditis	0.000	0.981	0.019
E06.4 Drug-induced thyroiditis	0.000	0.981	0.019
E06.2 Chronic thyroiditis with transient thyrotoxicosis	0.000	0.981	0.019
E06.1 Subacute thyroiditis	0.000	0.981	0.019
E06.0 Acute thyroiditis	0.000	0.981	0.019
E27.4 Other and unspecified adrenocortical insufficiency	0.000	0.981	0.019
E20.8 Other hypoparathyroidism	0.000	0.981	0.019
E20.1 Pseudohypoparathyroidism	0.000	0.981	0.019
E20.0 Idiopathic hypoparathyroidism	0.000	0.981	0.019
K14.9 Disease of tongue, unspecified	0.019	0.981	0.000
E27.3 Drug-induced adrenocortical insufficiency	0.000	0.981	0.019
E34.8 Other specified endocrine disorders	0.000	0.981	0.018
E34.5 Androgen resistance syndrome	0.000	0.981	0.018
E34.4 Constitutional tall stature	0.000	0.981	0.018
E34.3 Short stature, not elsewhere classified	0.000	0.981	0.018
E34.2 Ectopic hormone secretion, not elsewhere classified	0.000	0.981	0.018
E34.1 Other hypersecretion of intestinal hormones	0.000	0.981	0.018
E24.0 Pituitary-dependent Cushing's disease	0.000	0.982	0.018
E20.9 Hypoparathyroidism, unspecified	0.000	0.982	0.018
E24.8 Other Cushing's syndrome	0.000	0.982	0.018
E24.4 Alcohol-induced pseudo-Cushing's syndrome	0.000	0.982	0.018
E24.3 Ectopic ACTH syndrome	0.000	0.982	0.018
E24.1 Nelson's syndrome	0.000	0.982	0.018
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.000	0.983	0.017
E24.2 Drug-induced Cushing's syndrome	0.000	0.983	0.017
E65 Localised adiposity	0.000	0.983	0.017
E83.1 Disorders of iron metabolism	0.000	0.983	0.016
L53.9 Erythematous condition, unspecified	0.016	0.984	0.000
E55.9 Vitamin D deficiency, unspecified	0.000	0.984	0.016
E55.0 Rickets, active	0.000	0.984	0.016
E50.9 Vitamin A deficiency, unspecified	0.000	0.984	0.016
E50.8 Other manifestations of vitamin A deficiency	0.000	0.984	0.016
E50.7 Other ocular manifestations of vitamin A deficiency	0.000	0.984	0.016
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea	0.000	0.984	0.016
E50.5 Vitamin A deficiency with night blindness	0.000	0.984	0.016
E50.4 Vitamin A deficiency with keratomalacia	0.000	0.984	0.016
E50.3 Vitamin A deficiency with corneal ulceration and xerosis	0.000	0.984	0.016
E50.2 Vitamin A deficiency with corneal xerosis	0.000	0.984	0.016
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis	0.000	0.984	0.016
E50.0 Vitamin A deficiency with conjunctival xerosis	0.000	0.984	0.016
E51.9 Thiamine deficiency, unspecified	0.000	0.984	0.016
E51.8 Other manifestations of thiamine deficiency	0.000	0.984	0.016
E51.1 Beriberi	0.000	0.984	0.016
E56.9 Vitamin deficiency, unspecified	0.000	0.984	0.016
E56.8 Deficiency of other vitamins	0.000	0.984	0.016
E56.1 Deficiency of vitamin K	0.000	0.984	0.016
E56.0 Deficiency of vitamin E	0.000	0.984	0.016
E63.9 Nutritional deficiency, unspecified	0.000	0.984	0.016
E63.8 Other specified nutritional deficiencies	0.000	0.984	0.016
E63.1 Imbalance of constituents of food intake	0.000	0.984	0.016
E63.0 Essential fatty acid [EFA] deficiency	0.000	0.984	0.016
E64.9 Sequelae of unspecified nutritional deficiency	0.000	0.984	0.016
E64.8 Sequelae of other nutritional deficiencies	0.000	0.984	0.016
E64.3 Sequelae of rickets	0.000	0.984	0.016
E64.2 Sequelae of vitamin C deficiency	0.000	0.984	0.016
E64.1 Sequelae of vitamin A deficiency	0.000	0.984	0.016
E64.0 Sequelae of protein-energy malnutrition	0.000	0.984	0.016
E51.2 Wernicke's encephalopathy	0.000	0.984	0.016
E27.5 Adrenomedullary hyperfunction	0.000	0.984	0.016
E27.0 Other adrenocortical overactivity	0.000	0.984	0.016
E22.1 Hyperprolactinaemia	0.000	0.985	0.015
E06.9 Thyroiditis, unspecified	0.001	0.985	0.014
E67.8 Other specified hyperalimentation	0.000	0.985	0.014
E67.3 Hypervitaminosis D	0.000	0.985	0.014
E67.2 Megavitamin-B6 syndrome	0.000	0.985	0.014
E67.1 Hypercarotenaemia	0.000	0.985	0.014
E67.0 Hypervitaminosis A	0.000	0.985	0.014
E24.9 Cushing's syndrome, unspecified	0.000	0.985	0.014
E61.9 Deficiency of nutrient element, unspecified	0.000	0.986	0.014
E61.8 Deficiency of other specified nutrient elements	0.000	0.986	0.014
E61.7 Deficiency of multiple nutrient elements	0.000	0.986	0.014
E61.6 Vanadium deficiency	0.000	0.986	0.014
E61.5 Molybdenum deficiency	0.000	0.986	0.014
E61.4 Chromium deficiency	0.000	0.986	0.014
E61.3 Manganese deficiency	0.000	0.986	0.014
E61.0 Copper deficiency	0.000	0.986	0.014
E22.9 Hyperfunction of pituitary gland, unspecified	0.000	0.986	0.014
E22.8 Other hyperfunction of pituitary gland	0.000	0.986	0.014
E23 Hypofunction and other disorders of pituitary gland	0.000	0.986	0.014
E34.9 Endocrine disorder, unspecified	0.000	0.986	0.014
O32.8 Maternal care for other malpresentation of foetus	0.014	0.986	0.000
K14 Diseases of tongue	0.014	0.986	0.000
E61.1 Iron deficiency	0.000	0.986	0.014
E03.9 Hypothyroidism, unspecified	0.000	0.986	0.014
E22.0 Acromegaly and pituitary gigantism	0.000	0.987	0.013
E21.5 Disorder of parathyroid gland, unspecified	0.000	0.987	0.013
E61.2 Magnesium deficiency	0.000	0.987	0.013
E21.4 Other specified disorders of parathyroid gland	0.000	0.987	0.013
E27.8 Other specified disorders of adrenal gland	0.000	0.987	0.012
E27.2 Addisonian crisis	0.000	0.988	0.012
E21.2 Other hyperparathyroidism	0.000	0.988	0.012
K14.8 Other diseases of tongue	0.012	0.988	0.000
O32 Maternal care for known or suspected malpresentation of foetus	0.011	0.989	0.000
K14.6 Glossodynia	0.011	0.989	0.000
K14.0 Glossitis	0.011	0.989	0.000
E23.6 Other disorders of pituitary gland	0.000	0.989	0.011
E07.9 Disorder of thyroid, unspecified	0.000	0.989	0.011
D69.6 Thrombocytopenia, unspecified	0.011	0.989	0.000
O32.1 Maternal care for breech presentation	0.011	0.989	0.000
E27.9 Disorder of adrenal gland, unspecified	0.000	0.989	0.010
E23.3 Hypothalamic dysfunction, not elsewhere classified	0.000	0.989	0.010
E23.1 Drug-induced hypopituitarism	0.000	0.989	0.010
E21.1 Secondary hyperparathyroidism, not elsewhere classified	0.000	0.989	0.010
E21.3 Hyperparathyroidism, unspecified	0.000	0.990	0.010
E21.0 Primary hyperparathyroidism	0.000	0.990	0.010
E27.1 Primary adrenocortical insufficiency	0.000	0.990	0.010
K14.5 Plicated tongue	0.010	0.990	0.000
K14.4 Atrophy of tongue papillae	0.010	0.990	0.000
K14.3 Hypertrophy of tongue papillae	0.010	0.990	0.000
K14.2 Median rhomboid glossitis	0.010	0.990	0.000
K14.1 Geographic tongue	0.010	0.990	0.000
M25.46 Effusion of joint (Lower leg)	0.000	0.990	0.010
E53 Deficiency of other B group vitamins	0.001	0.990	0.009
O32.9 Maternal care for malpresentation of foetus, unspecified	0.010	0.990	0.000
E23.7 Disorder of pituitary gland, unspecified	0.000	0.990	0.009
O32.5 Maternal care for multiple gestation with malpresentation of one foetus or more	0.009	0.991	0.000
L53 Other erythematous conditions	0.009	0.991	0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias	0.000	0.991	0.009
O46.9 Antepartum haemorrhage, unspecified	0.009	0.991	0.000
O32.6 Maternal care for compound presentation	0.008	0.992	0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems	0.008	0.992	0.000
O46 Antepartum haemorrhage, not elsewhere classified	0.008	0.992	0.000
O43.1 Malformation of placenta	0.008	0.992	0.000
E78.4 Other hyperlipidaemia	0.000	0.992	0.008
O32.3 Maternal care for face, brow and chin presentation	0.008	0.992	0.000
E66 Obesity	0.000	0.992	0.008
O43 Placental disorders	0.008	0.992	0.000
O36.8 Maternal care for other specified foetal problems	0.008	0.992	0.000
O32.2 Maternal care for transverse and oblique lie	0.008	0.992	0.000
E23.2 Diabetes insipidus	0.000	0.992	0.007
O30 Multiple gestation	0.008	0.992	0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.008	0.992	0.000
E53.1 Pyridoxine deficiency	0.001	0.993	0.007
E53.0 Riboflavin deficiency	0.001	0.993	0.007
O36 Maternal care for other known or suspected foetal problems	0.007	0.993	0.000
O30.0 Twin pregnancy	0.007	0.993	0.000
O32.4 Maternal care for high head at term	0.007	0.993	0.000
E78.6 Lipoprotein deficiency	0.000	0.993	0.007
O33 Maternal care for known or suspected disproportion	0.007	0.993	0.000
L53.3 Other chronic figurate erythema	0.007	0.993	0.000
L53.2 Erythema marginatum	0.007	0.993	0.000
L53.1 Erythema annulare centrifugum	0.007	0.993	0.000
E06.3 Autoimmune thyroiditis	0.001	0.993	0.006
O34 Maternal care for known or suspected abnormality of pelvic organs	0.007	0.993	0.000
I80.1 Phlebitis and thrombophlebitis of femoral vein	0.007	0.993	0.000
L53.0 Toxic erythema	0.006	0.993	0.000
E78.3 Hyperchylomicronaemia	0.000	0.993	0.006
E78.2 Mixed hyperlipidaemia	0.000	0.993	0.006
O45 Premature separation of placenta [abruptio placentae]	0.006	0.994	0.000
O42 Premature rupture of membranes	0.006	0.994	0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone	0.000	0.994	0.006
C84.5 Other and unspecified T-cell lymphomas	0.006	0.994	0.000
O32.0 Maternal care for unstable lie	0.006	0.994	0.000
N30.3 Trigonitis	0.000	0.994	0.006
O43.9 Placental disorder, unspecified	0.006	0.994	0.000
O42.9 Premature rupture of membranes, unspecified	0.006	0.994	0.000
E66.2 Extreme obesity with alveolar hypoventilation	0.000	0.994	0.006
O46.0 Antepartum haemorrhage with coagulation defect	0.006	0.994	0.000
O31 Complications specific to multiple gestation	0.006	0.994	0.000
C81.9 Hodgkin's disease, unspecified	0.006	0.994	0.000
O34.4 Maternal care for other abnormalities of cervix	0.006	0.994	0.000
O36.1 Maternal care for other isoimmunisation	0.006	0.994	0.000
E66.1 Drug-induced obesity	0.000	0.994	0.006
I80.2 Phlebitis and thrombophlebitis of other deep vessels of lower extremities	0.006	0.994	0.000
O36.5 Maternal care for poor foetal growth	0.006	0.994	0.000
E78.1 Pure hyperglyceridaemia	0.000	0.994	0.006
G44.0 Cluster headache syndrome	0.006	0.994	0.000
O33.5 Maternal care for disproportion due to unusually large foetus	0.006	0.994	0.000
O43.2 Morbidly adherent placenta	0.006	0.994	0.000
O30.1 Triplet pregnancy	0.006	0.994	0.000
O36.7 Maternal care for viable foetus in abdominal pregnancy	0.006	0.994	0.000
E53.9 Vitamin B deficiency, unspecified	0.001	0.994	0.005
D80-D89 Certain disorders involving the immune mechanism	0.006	0.994	0.000
O30.9 Multiple gestation, unspecified	0.006	0.994	0.000
O30.8 Other multiple gestation	0.006	0.994	0.000
O30.2 Quadruplet pregnancy	0.006	0.994	0.000
G44.2 Tension-type headache	0.006	0.994	0.000
O35 Maternal care for known or suspected foetal abnormality and damage	0.006	0.994	0.000
O43.0 Placental transfusion syndromes	0.005	0.994	0.000
O46.8 Other antepartum haemorrhage	0.005	0.994	0.000
L52 Erythema nodosum	0.006	0.994	0.000
E66.0 Obesity due to excess calories	0.000	0.994	0.005
G44 Other headache syndromes	0.006	0.994	0.000
O36.4 Maternal care for intra-uterine death	0.005	0.994	0.000
L50-L54 Urticaria and erythema	0.006	0.994	0.000
L53.8 Other specified erythematous conditions	0.005	0.995	0.000
O36.2 Maternal care for hydrops foetalis	0.005	0.995	0.000
O34.2 Maternal care due to uterine scar from previous surgery	0.005	0.995	0.000
O42.1 Premature rupture of membranes, onset of labour after 24 hours	0.005	0.995	0.000
D84 Other immunodeficiencies	0.005	0.995	0.000
I80 Phlebitis and thrombophlebitis	0.005	0.995	0.000
E23.0 Hypopituitarism	0.000	0.995	0.005
O45.9 Premature separation of placenta, unspecified	0.005	0.995	0.000
O41 Other disorders of amniotic fluid and membranes	0.005	0.995	0.000
O33.9 Maternal care for disproportion, unspecified	0.005	0.995	0.000
O40 Polyhydramnios	0.005	0.995	0.000
O33.8 Maternal care for disproportion of other origin	0.005	0.995	0.000
O33.7 Maternal care for disproportion due to other foetal deformities	0.005	0.995	0.000
O33.6 Maternal care for disproportion due to hydrocephalic foetus	0.005	0.995	0.000
O33.4 Maternal care for disproportion of mixed maternal and foetal origin	0.005	0.995	0.000
O33.3 Maternal care for disproportion due to outlet contraction of pelvis	0.005	0.995	0.000
O33.2 Maternal care for disproportion due to inlet contraction of pelvis	0.005	0.995	0.000
O33.1 Maternal care for disproportion due to generally contracted pelvis	0.005	0.995	0.000
O33.0 Maternal care for disproportion due to deformity of maternal pelvic bones	0.005	0.995	0.000
O34.9 Maternal care for abnormality of pelvic organ, unspecified	0.005	0.995	0.000
O34.6 Maternal care for abnormality of vagina	0.005	0.995	0.000
O34.5 Maternal care for other abnormalities of gravid uterus	0.005	0.995	0.000
O34.1 Maternal care for tumour of corpus uteri	0.005	0.995	0.000
O34.0 Maternal care for congenital malformation of uterus	0.005	0.995	0.000
G44.4 Drug-induced headache, not elsewhere classified	0.005	0.995	0.000
H35.7 Separation of retinal layers	0.005	0.995	0.000
D83 Common variable immunodeficiency	0.005	0.995	0.000
O34.3 Maternal care for cervical incompetence	0.005	0.995	0.000
O45.8 Other premature separation of placenta	0.005	0.995	0.000
O45.0 Premature separation of placenta with coagulation defect	0.005	0.995	0.000
O34.8 Maternal care for other abnormalities of pelvic organs	0.005	0.995	0.000
O42.2 Premature rupture of membranes, labour delayed by therapy	0.005	0.995	0.000
O36.6 Maternal care for excessive foetal growth	0.005	0.995	0.000
E10-E14 Diabetes mellitus	0.000	0.995	0.005
D84.8 Other specified immunodeficiencies	0.005	0.995	0.000
D80 Immunodeficiency with predominantly antibody defects	0.005	0.995	0.000
G44.3 Chronic posttraumatic headache	0.005	0.995	0.000
H35 Other retinal disorders	0.005	0.995	0.000
I80.0 Phlebitis and thrombophlebitis of superficial vessels of lower extremities	0.005	0.995	0.000
H35.6 Retinal haemorrhage	0.005	0.995	0.000
S82.21 Fracture of shaft of tibia (open)	0.005	0.995	0.000
H35.5 Hereditary retinal dystrophy	0.005	0.995	0.000
O31.8 Other complications specific to multiple gestation	0.004	0.995	0.000
O31.2 Continuing pregnancy after intra-uterine death of one foetus or more	0.004	0.995	0.000
O31.1 Continuing pregnancy after abortion of one foetus or more	0.004	0.995	0.000
O31.0 Papyraceous foetus	0.004	0.995	0.000
D84.9 Immunodeficiency, unspecified	0.005	0.995	0.000
O43.8 Other placental disorders	0.005	0.995	0.000
O35.8 Maternal care for other (suspected) foetal abnormality and damage	0.005	0.995	0.000
O41.1 Infection of amniotic sac and membranes	0.005	0.995	0.000
O35.0 Maternal care for (suspected) central nervous system malformation in foetus	0.004	0.995	0.000
D83.9 Common variable immunodeficiency, unspecified	0.004	0.995	0.000
D82 Immunodeficiency associated with other major defects	0.004	0.995	0.000
O35.9 Maternal care for (suspected) foetal abnormality and damage, unspecified	0.004	0.996	0.000
O36.0 Maternal care for rhesus isoimmunisation	0.004	0.996	0.000
D81 Combined immunodeficiencies	0.004	0.996	0.000
I80.9 Phlebitis and thrombophlebitis of unspecified site	0.004	0.996	0.000
O35.7 Maternal care for (suspected) damage to foetus by other medical procedures	0.004	0.996	0.000
O35.6 Maternal care for (suspected) damage to foetus by radiation	0.004	0.996	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations