TreeWAS – Variant ID: rs549270

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
E10 Insulin-dependent diabetes mellitus	1.000	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	1.000	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	1.000	0.000
# Top node	1.000	0.000
Chapter II Neoplasms	1.000	0.000
E10.9 Without complications	1.000	0.000
E10-E14 Diabetes mellitus	1.000	0.000
E03.9 Hypothyroidism, unspecified	1.000	0.000
E03 Other hypothyroidism	0.999	0.001
E00-E07 Disorders of thyroid gland	0.999	0.001
Chapter V Mental and behavioural disorders	0.996	0.004
E10.3 With ophthalmic complications	0.994	0.006
T36-T50 Poisoning by drugs, medicaments and biological substances	0.993	0.007
F30-F39 Mood [affective] disorders	0.988	0.012
Chapter VII Diseases of the eye and adnexa	0.984	0.016
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.975	0.025
H30-H36 Disorders of choroid and retina	0.970	0.030
C64-C68 Malignant neoplasms of urinary tract	0.966	0.034
D37-D48 Neoplasms of uncertain or unknown behaviour	0.963	0.037
F31 Bipolar affective disorder	0.961	0.039
C67 Malignant neoplasm of bladder	0.953	0.047
H36 Retinal disorders in diseases classified elsewhere	0.952	0.048
T66-T78 Other and unspecified effects of external causes	0.951	0.049
D10-D36 Benign neoplasms	0.946	0.054
E10.4 With neurological complications	0.942	0.058
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.941	0.059
H36.0 Diabetic retinopathy	0.940	0.060
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.938	0.062
S20-S29 Injuries to the thorax	0.937	0.063
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.936	0.064
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.932	0.068
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.931	0.069
F40-F48 Neurotic, stress-related and somatoform disorders	0.925	0.075
E10.1 With ketoacidosis	0.919	0.081
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.918	0.082
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.915	0.085
C67.9 Bladder, unspecified	0.909	0.091
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.909	0.091
S60-S69 Injuries to the wrist and hand	0.908	0.092
T78 Adverse effects, not elsewhere classified	0.908	0.092
D12 Benign neoplasm of colon, rectum, anus and anal canal	0.901	0.099
D32 Benign neoplasm of meninges	0.900	0.100
C43-C44 Melanoma and other malignant neoplasms of skin	0.898	0.102
F41 Other anxiety disorders	0.894	0.106
D12.5 Sigmoid colon	0.894	0.106
S50-S59 Injuries to the elbow and forearm	0.889	0.111
C34 Malignant neoplasm of bronchus and lung	0.888	0.112
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.884	0.116
F31.3 Bipolar affective disorder, current episode mild or moderate depression	0.884	0.116
D00-D09 In situ neoplasms	0.882	0.118
T78.4 Allergy, unspecified	0.879	0.121
S32 Fracture of lumbar spine and pelvis	0.869	0.131
H25-H28 Disorders of lens	0.868	0.132
C82 Follicular [nodular] non-Hodgkin's lymphoma	0.865	0.135
S39 Other and unspecified injuries of abdomen, lower back and pelvis	0.863	0.137
F30 Manic episode	0.860	0.140
F41.2 Mixed anxiety and depressive disorder	0.860	0.140
S90-S99 Injuries to the ankle and foot	0.859	0.141
M70-M79 Other soft tissue disorders	0.858	0.142
S30 Superficial injury of abdomen, lower back and pelvis	0.858	0.142
S40-S49 Injuries to the shoulder and upper arm	0.856	0.144
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs	0.855	0.145
E16 Other disorders of pancreatic internal secretion	0.855	0.145
Chapter XX External causes of morbidity and mortality	0.850	0.150
T88 Other complications of surgical and medical care, not elsewhere classified	0.848	0.152
D32.0 Cerebral meninges	0.846	0.154
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.836	0.164
M20-M25 Other joint disorders	0.836	0.164
T43.3 Phenothiazine antipsychotics and neuroleptics	0.835	0.164
D23 Other benign neoplasms of skin	0.830	0.170
E10.5 With peripheral circulatory complications	0.830	0.170
H26 Other cataract	0.830	0.170
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.829	0.171
T83 Complications of genito-urinary prosthetic devices, implants and grafts	0.824	0.176
C15-C26 Malignant neoplasms of digestive organs	0.822	0.178
S22 Fracture of rib(s), sternum and thoracic spine	0.822	0.178
S00-S09 Injuries to the head	0.821	0.179
T39.1 4-Aminophenol derivatives	0.821	0.179
T43.0 Tricyclic and tetracyclic antidepressants	0.820	0.180
H34 Retinal vascular occlusions	0.818	0.182
D23.1 Skin of eyelid, including canthus	0.818	0.182
M75 Shoulder lesions	0.816	0.184
S61 Open wound of wrist and hand	0.815	0.185
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.814	0.186
E16.2 Hypoglycaemia, unspecified	0.811	0.189
C85 Other and unspecified types of non-Hodgkin's lymphoma	0.809	0.191
C34.1 Upper lobe, bronchus or lung	0.809	0.191
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms	0.809	0.191
S20 Superficial injury of thorax	0.808	0.192
D41 Neoplasm of uncertain or unknown behaviour of urinary organs	0.808	0.192
C81 Hodgkin's disease	0.806	0.194
H46-H48 Disorders of optic nerve and visual pathways	0.805	0.195
S52 Fracture of forearm	0.804	0.196
S64 Injury of nerves at wrist and hand level	0.804	0.196
F41.1 Generalised anxiety disorder	0.802	0.198
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.801	0.199
T88.7 Unspecified adverse effect of drug or medicament	0.798	0.202
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.798	0.202
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.796	0.204
D05 Carcinoma in situ of breast	0.794	0.206
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms	0.793	0.207
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.793	0.207
M86-M90 Other osteopathies	0.791	0.209
C34.9 Bronchus or lung, unspecified	0.791	0.209
D36 Benign neoplasm of other and unspecified sites	0.790	0.210
D10 Benign neoplasm of mouth and pharynx	0.790	0.210
D68 Other coagulation defects	0.787	0.213
T15-T19 Effects of foreign body entering through natural orifice	0.786	0.214
D26 Other benign neoplasms of uterus	0.786	0.214
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.786	0.214
F32 Depressive episode	0.784	0.216
S39.9 Unspecified injury of abdomen, lower back and pelvis	0.784	0.216
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system	0.783	0.217
M75.1 Rotator cuff syndrome	0.783	0.217
S61.0 Open wound of finger(s) without damage to nail	0.782	0.218
C67.0 Trigone of bladder	0.781	0.219
F33 Recurrent depressive disorder	0.780	0.220
E13 Other specified diabetes mellitus	0.779	0.221
C43 Malignant melanoma of skin	0.778	0.222
C67.5 Bladder neck	0.778	0.222
D50-D53 Nutritional anaemias	0.773	0.227
S42 Fracture of shoulder and upper arm	0.773	0.227
F60-F69 Disorders of adult personality and behaviour	0.770	0.230
F30.0 Hypomania	0.769	0.231
T39.0 Salicylates	0.768	0.232
H26.9 Cataract, unspecified	0.767	0.233
F34 Persistent mood [affective] disorders	0.767	0.233
S06 Intracranial injury	0.766	0.234
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.765	0.235
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.765	0.235
C67.2 Lateral wall of bladder	0.761	0.239
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.761	0.239
D39 Neoplasm of uncertain or unknown behaviour of female genital organs	0.759	0.241
S10-S19 Injuries to the neck	0.759	0.241
F99-F99 Unspecified mental disorder	0.757	0.243
C66 Malignant neoplasm of ureter	0.755	0.245
D12.6 Colon, unspecified	0.754	0.246
Q20-Q28 Congenital malformations of the circulatory system	0.753	0.246
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.750	0.250
C82.9 Follicular non-Hodgkin's lymphoma, unspecified	0.749	0.251
Chapter VI Diseases of the nervous system	0.749	0.251
D32.9 Meninges, unspecified	0.749	0.251
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.746	0.253
M25 Other joint disorders, not elsewhere classified	0.746	0.254
T43.2 Other and unspecified antidepressants	0.746	0.254
E03.8 Other specified hypothyroidism	0.745	0.255
T85 Complications of other internal prosthetic devices, implants and grafts	0.744	0.256
C44 Other malignant neoplasms of skin	0.744	0.256
H53-H54 Visual disturbances and blindness	0.743	0.257
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.743	0.257
D14 Benign neoplasm of middle ear and respiratory system	0.742	0.258
M23 Internal derangement of knee	0.741	0.259
T78.0 Anaphylactic shock due to adverse food reaction	0.741	0.259
S27 Injury of other and unspecified intrathoracic organs	0.738	0.262
H55-H59 Other disorders of eye and adnexa	0.738	0.262
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs	0.738	0.262
C67.1 Dome of bladder	0.737	0.263
Q80-Q89 Other congenital malformations	0.736	0.264
C84 Peripheral and cutaneous T-cell lymphomas	0.733	0.267
H35 Other retinal disorders	0.733	0.267
D11 Benign neoplasm of major salivary glands	0.733	0.267
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.731	0.269
T68 Hypothermia	0.730	0.270
Q50-Q56 Congenital malformations of genital organs	0.728	0.272
C24 Malignant neoplasm of other and unspecified parts of biliary tract	0.728	0.272
S52.0 Fracture of upper end of ulna	0.726	0.274
F31.0 Bipolar affective disorder, current episode hypomanic	0.726	0.274
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.724	0.276
S30.1 Contusion of abdominal wall	0.723	0.277
D27 Benign neoplasm of ovary	0.722	0.278
S92 Fracture of foot, except ankle	0.722	0.278
S50 Superficial injury of forearm	0.721	0.279
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms	0.719	0.281
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.719	0.281
D13 Benign neoplasm of other and ill-defined parts of digestive system	0.719	0.281
T83.1 Mechanical complication of other urinary devices and implants	0.718	0.282
D37.5 Rectum	0.718	0.282
D47.3 Essential (haemorrhagic) thrombocythaemia	0.718	0.282
E10.8 With unspecified complications	0.717	0.283
E10.7 With multiple complications	0.717	0.283
E10.6 With other specified complications	0.717	0.283
E10.2 With renal complications	0.717	0.283
E10.0 With coma	0.717	0.283
E40-E46 Malnutrition	0.717	0.283
T33-T35 Frostbite	0.717	0.283
T26-T28 Burns and corrosions confined to eye and internal organs	0.717	0.283
T20-T25 Burns and corrosions of external body surface, specified by site	0.717	0.283
T00-T07 Injuries involving multiple body regions	0.717	0.283
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.717	0.283
C40-C41 Malignant neoplasms of bone and articular cartilage	0.717	0.283
F80-F89 Disorders of psychological development	0.717	0.283
E12 Malnutrition-related diabetes mellitus	0.717	0.283
E03.5 Myxoedema coma	0.717	0.283
E03.4 Atrophy of thyroid (acquired)	0.717	0.283
E03.3 Postinfectious hypothyroidism	0.717	0.283
E03.2 Hypothyroidism due to medicaments and other exogenous substances	0.717	0.283
E03.1 Congenital hypothyroidism without goitre	0.717	0.283
E03.0 Congenital hypothyroidism with diffuse goitre	0.717	0.283
E01 Iodine-deficiency-related thyroid disorders and allied conditions	0.716	0.283
E00 Congenital iodine-deficiency syndrome	0.716	0.283
E02 Subclinical iodine-deficiency hypothyroidism	0.716	0.283
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.716	0.284
D09 Carcinoma in situ of other and unspecified sites	0.716	0.284
S60 Superficial injury of wrist and hand	0.714	0.286
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.714	0.286
F70-F79 Mental retardation	0.714	0.286
H40-H42 Glaucoma	0.714	0.286
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.712	0.288
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.712	0.288
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.712	0.288
T46 Poisoning by agents primarily affecting the cardiovascular system	0.712	0.288
T41 Poisoning by anaesthetics and therapeutic gases	0.712	0.288
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.712	0.288
T36 Poisoning by systemic antibiotics	0.712	0.288
X20-X29 Contact with venomous animals and plants	0.711	0.289
S42.0 Fracture of clavicle	0.709	0.291
E07 Other disorders of thyroid	0.709	0.291
F38 Other mood [affective] disorders	0.709	0.291
F39 Unspecified mood [affective] disorder	0.709	0.291
Chapter I Certain infectious and parasitic diseases	0.708	0.292
D37.0 Lip, oral cavity and pharynx	0.707	0.293
M76 Enthesopathies of lower limb, excluding foot	0.707	0.293
F31.9 Bipolar affective disorder, unspecified	0.706	0.294
E06 Thyroiditis	0.705	0.295
C44.1 Skin of eyelid, including canthus	0.705	0.295
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.704	0.296
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level	0.703	0.297
H26.8 Other specified cataract	0.702	0.298
S32.7 Multiple fractures of lumbar spine and pelvis	0.702	0.298
Q38-Q45 Other congenital malformations of the digestive system	0.702	0.298
D05.1 Intraductal carcinoma in situ	0.701	0.299
C67.4 Posterior wall of bladder	0.701	0.299
H27 Other disorders of lens	0.701	0.299
D36.7 Other specified sites	0.701	0.299
C92 Myeloid leukaemia	0.700	0.300
C82.7 Other types of follicular non-Hodgkin's lymphoma	0.699	0.301
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis	0.699	0.301
S37 Injury of urinary and pelvic organs	0.699	0.301
S36 Injury of intra-abdominal organs	0.699	0.301
S35 Injury of blood vessels at abdomen, lower back and pelvis level	0.699	0.301
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level	0.699	0.301
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis	0.699	0.301
S31 Open wound of abdomen, lower back and pelvis	0.699	0.301
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.699	0.301
S32.0 Fracture of lumbar vertebra	0.698	0.302
C81.1 Nodular sclerosis	0.697	0.303
D41.4 Bladder	0.696	0.304
H20 Iridocyclitis	0.696	0.304
D03 Melanoma in situ	0.696	0.304
H32 Chorioretinal disorders in diseases classified elsewhere	0.695	0.305
H31 Other disorders of choroid	0.695	0.305
H30 Chorioretinal inflammation	0.695	0.305
F32.2 Severe depressive episode without psychotic symptoms	0.695	0.305
C82.1 Mixed small cleaved and large cell, follicular	0.694	0.306
G90-G99 Other disorders of the nervous system	0.694	0.306
C23 Malignant neoplasm of gallbladder	0.694	0.306
T83.0 Mechanical complication of urinary (indwelling) catheter	0.693	0.307
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.693	0.307
C68 Malignant neoplasm of other and unspecified urinary organs	0.693	0.307
C65 Malignant neoplasm of renal pelvis	0.693	0.307
S99 Other and unspecified injuries of ankle and foot	0.692	0.308
S22.4 Multiple fractures of ribs	0.692	0.308
D50 Iron deficiency anaemia	0.691	0.308
C43.4 Malignant melanoma of scalp and neck	0.691	0.309
T92 Sequelae of injuries of upper limb	0.691	0.309
D05.0 Lobular carcinoma in situ	0.691	0.309
M91-M94 Chondropathies	0.690	0.309
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands	0.690	0.310
D42 Neoplasm of uncertain or unknown behaviour of meninges	0.690	0.310
D40 Neoplasm of uncertain or unknown behaviour of male genital organs	0.690	0.310
H34.8 Other retinal vascular occlusions	0.690	0.310
F31.8 Other bipolar affective disorders	0.689	0.311
F31.7 Bipolar affective disorder, currently in remission	0.689	0.311
F31.6 Bipolar affective disorder, current episode mixed	0.689	0.311
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms	0.689	0.311
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.685	0.314
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.685	0.315
C44.4 Skin of scalp and neck	0.685	0.315
M00-M03 Infectious arthropathies	0.684	0.316
C67.8 Overlapping lesion of bladder	0.683	0.317
C67.7 Urachus	0.683	0.317
C67.6 Ureteric orifice	0.683	0.317
C67.3 Anterior wall of bladder	0.683	0.317
H36.8 Other retinal disorders in diseases classified elsewhere	0.683	0.317
M45-M49 Spondylopathies	0.683	0.317
M60-M63 Disorders of muscles	0.682	0.318
T75 Effects of other external causes	0.682	0.318
T74 Maltreatment syndromes	0.682	0.318
T73 Effects of other deprivation	0.682	0.318
T70 Effects of air pressure and water pressure	0.682	0.318
T69 Other effects of reduced temperature	0.682	0.318
T67 Effects of heat and light	0.682	0.318
T71 Asphyxiation	0.682	0.318
T66 Unspecified effects of radiation	0.682	0.318
E20-E35 Disorders of other endocrine glands	0.682	0.318
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts	0.682	0.318
V40-V49 Car occupant injured in transport accident	0.681	0.319
E05 Thyrotoxicosis [hyperthyroidism]	0.681	0.319
S30.2 Contusion of external genital organs	0.681	0.319
M75.0 Adhesive capsulitis of shoulder	0.681	0.319
D10.1 Tongue	0.680	0.320
D24 Benign neoplasm of breast	0.680	0.320
D23.9 Skin, unspecified	0.680	0.320
D31 Benign neoplasm of eye and adnexa	0.678	0.322
D29 Benign neoplasm of male genital organs	0.678	0.322
D28 Benign neoplasm of other and unspecified female genital organs	0.678	0.322
D20 Benign neoplasm of soft tissue of retroperitoneum and peritoneum	0.678	0.322
D19 Benign neoplasm of mesothelial tissue	0.678	0.322
D16 Benign neoplasm of bone and articular cartilage	0.678	0.322
D15 Benign neoplasm of other and unspecified intrathoracic organs	0.678	0.322
S32.5 Fracture of pubis	0.678	0.322
C19 Malignant neoplasm of rectosigmoid junction	0.678	0.322
M75.4 Impingement syndrome of shoulder	0.676	0.324
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue	0.675	0.325
C95 Leukaemia of unspecified cell type	0.675	0.325
C94 Other leukaemias of specified cell type	0.675	0.325
C93 Monocytic leukaemia	0.675	0.325
C88 Malignant immunoproliferative diseases	0.675	0.325
C86 Other specified types of T/NK-cell lymphoma	0.675	0.325
C34.2 Middle lobe, bronchus or lung	0.674	0.325
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.674	0.326
F43 Reaction to severe stress, and adjustment disorders	0.674	0.326
S22.0 Fracture of thoracic vertebra	0.673	0.327
M77 Other enthesopathies	0.673	0.327
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction	0.673	0.327
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts	0.673	0.327
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.672	0.327
T39.4 Antirheumatics, not elsewhere classified	0.672	0.327
T39.2 Pyrazolone derivatives	0.672	0.327
S28 Crushing injury of thorax and traumatic amputation of part of thorax	0.672	0.328
S26 Injury of heart	0.672	0.328
S25 Injury of blood vessels of thorax	0.672	0.328
S24 Injury of nerves and spinal cord at thorax level	0.672	0.328
S23 Dislocation, sprain and strain of joints and ligaments of thorax	0.672	0.328
S21 Open wound of thorax	0.672	0.328
M24 Other specific joint derangements	0.672	0.328
T43.9 Psychotropic drug, unspecified	0.671	0.329
T43.8 Other psychotropic drugs, not elsewhere classified	0.671	0.329
T43.6 Psychostimulants with abuse potential	0.671	0.329
T43.4 Butyrophenone and thioxanthene neuroleptics	0.671	0.329
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.671	0.329
D30 Benign neoplasm of urinary organs	0.670	0.330
S20.3 Other superficial injuries of front wall of thorax	0.670	0.330
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs	0.668	0.332
C38 Malignant neoplasm of heart, mediastinum and pleura	0.668	0.332
C31 Malignant neoplasm of accessory sinuses	0.668	0.332
C30 Malignant neoplasm of nasal cavity and middle ear	0.668	0.332
C37 Malignant neoplasm of thymus	0.668	0.332
C33 Malignant neoplasm of trachea	0.668	0.332
T87 Complications peculiar to reattachment and amputation	0.667	0.332
T86 Failure and rejection of transplanted organs and tissues	0.667	0.332
T80 Complications following infusion, transfusion and therapeutic injection	0.667	0.332
M34 Systemic sclerosis	0.667	0.333
Y57 Other and unspecified drugs and medicaments	0.667	0.333
W00-W19 Falls	0.666	0.334
Chapter XXII Codes for special purposes	0.666	0.334
S01 Open wound of head	0.666	0.334
S64.4 Injury of digital nerve of other finger	0.666	0.334
S42.00 Fracture of clavicle (closed)	0.664	0.336
T93 Sequelae of injuries of lower limb	0.663	0.337
D50.8 Other iron deficiency anaemias	0.663	0.337
F48 Other neurotic disorders	0.663	0.337
F44 Dissociative [conversion] disorders	0.663	0.337
C85.1 B-cell lymphoma, unspecified	0.663	0.337
M89 Other disorders of bone	0.662	0.338
S32.8 Fracture of other and unspecified parts of lumbar spine and pelvis	0.662	0.338
C85.9 Non-Hodgkin's lymphoma, unspecified type	0.662	0.338
S32.3 Fracture of ilium	0.662	0.338
T78.1 Other adverse food reactions, not elsewhere classified	0.662	0.338
C24.0 Extrahepatic bile duct	0.660	0.340
D33 Benign neoplasm of brain and other parts of central nervous system	0.658	0.342
F42 Obsessive-compulsive disorder	0.658	0.342
C22 Malignant neoplasm of liver and intrahepatic bile ducts	0.657	0.343
S29 Other and unspecified injuries of thorax	0.657	0.343
H26.2 Complicated cataract	0.656	0.343
E15 Nondiabetic hypoglycaemic coma	0.656	0.344
M80-M85 Disorders of bone density and structure	0.656	0.344
C26 Malignant neoplasm of other and ill-defined digestive organs	0.656	0.344
M33 Dermatopolymyositis	0.654	0.345
M22 Disorders of patella	0.654	0.346
D43.2 Brain, unspecified	0.654	0.346
D68.2 Hereditary deficiency of other clotting factors	0.653	0.347
F52 Sexual dysfunction, not caused by organic disorder or disease	0.653	0.347
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.651	0.348
Q35-Q37 Cleft lip and cleft palate	0.651	0.348
Q30-Q34 Congenital malformations of the respiratory system	0.651	0.348
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.651	0.348
S65 Injury of blood vessels at wrist and hand level	0.651	0.349
T78.9 Adverse effect, unspecified	0.651	0.349
T78.8 Other adverse effects, not elsewhere classified	0.651	0.349
S20.8 Superficial injuries of other and unspecified parts of thorax	0.650	0.350
D12.2 Ascending colon	0.650	0.350
S52.00 Fracture of upper end of ulna (closed)	0.649	0.351
D68.6 Other Thrombophilia	0.648	0.351
D68.8 Other specified coagulation defects	0.647	0.353
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites	0.647	0.353
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.646	0.354
D12.9 Anus and anal canal	0.646	0.354
D12.1 Appendix	0.646	0.354
C32 Malignant neoplasm of larynx	0.646	0.354
H46 Optic neuritis	0.646	0.354
D32.1 Spinal meninges	0.645	0.354
D45 Polycythaemia vera	0.644	0.356
M87 Osteonecrosis	0.644	0.356
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level	0.643	0.356
M21 Other acquired deformities of limbs	0.642	0.358
V20-V29 Motorcycle rider injured in transport accident	0.642	0.358
F41.8 Other specified anxiety disorders	0.641	0.359
F41.3 Other mixed anxiety disorders	0.641	0.359
D04 Carcinoma in situ of skin	0.641	0.359
G35-G37 Demyelinating diseases of the central nervous system	0.639	0.361
S52.6 Fracture of lower end of both ulna and radius	0.638	0.362
S59 Other and unspecified injuries of forearm	0.637	0.362
S58 Traumatic amputation of forearm	0.637	0.362
S57 Crushing injury of forearm	0.637	0.362
S56 Injury of muscle and tendon at forearm level	0.637	0.362
S55 Injury of blood vessels at forearm level	0.637	0.362
S54 Injury of nerves at forearm level	0.637	0.362
S53 Dislocation, sprain and strain of joints and ligaments of elbow	0.637	0.362
S67 Crushing injury of wrist and hand	0.637	0.363
S64.1 Injury of median nerve at wrist and hand level	0.637	0.363
C34.8 Overlapping lesion of bronchus and lung	0.636	0.364
T79-T79 Certain early complications of trauma	0.636	0.364
T17 Foreign body in respiratory tract	0.636	0.364
T42.4 Benzodiazepines	0.636	0.364
S30.8 Other superficial injuries of abdomen, lower back and pelvis	0.635	0.365
D21 Other benign neoplasms of connective and other soft tissue	0.635	0.365
D46 Myelodysplastic syndromes	0.634	0.365
F33.3 Recurrent depressive disorder, current episode severe with psychotic symptoms	0.634	0.366
D55-D59 Haemolytic anaemias	0.634	0.366
X60-X84 Intentional self-harm	0.634	0.366
M25.8 Other specified joint disorders	0.633	0.367
D02 Carcinoma in situ of middle ear and respiratory system	0.633	0.367
D01 Carcinoma in situ of other and unspecified digestive organs	0.633	0.367
D00 Carcinoma in situ of oral cavity, oesophagus and stomach	0.633	0.367
H33 Retinal detachments and breaks	0.633	0.367
S06.9 Intracranial injury, unspecified	0.632	0.368
S22.5 Flail chest	0.631	0.369
S30.0 Contusion of lower back and pelvis	0.631	0.369
Q27 Other congenital malformations of peripheral vascular system	0.628	0.372
T11 Other injuries of upper limb, level unspecified	0.627	0.373
D26.1 Corpus uteri	0.627	0.373
M23.2 Derangement of meniscus due to old tear or injury	0.627	0.373
H26.0 Infantile, juvenile and presenile cataract	0.626	0.374
D26.0 Cervix uteri	0.626	0.374
D37.7 Other digestive organs	0.626	0.374
M70 Soft tissue disorders related to use, overuse and pressure	0.624	0.376
T78.2 Anaphylactic shock, unspecified	0.624	0.376
S52.1 Fracture of upper end of radius	0.623	0.377
S32.2 Fracture of coccyx	0.623	0.377
S32.1 Fracture of sacrum	0.623	0.377
H34.2 Other retinal artery occlusions	0.623	0.377
H28 Cataract and other disorders of lens in diseases classified elsewhere	0.622	0.378
H35.0 Background retinopathy and retinal vascular changes	0.622	0.378
G70-G73 Diseases of myoneural junction and muscle	0.622	0.378
X40-X49 Accidental poisoning by and exposure to noxious substances	0.621	0.379
E13.9 Without complications	0.621	0.379
D68.9 Coagulation defect, unspecified	0.621	0.379
H47 Other disorders of optic [2nd] nerve and visual pathways	0.621	0.379
M71 Other bursopathies	0.621	0.379
C82.6 Cutaneous follicle centre lymphoma	0.620	0.380
C82.5 Diffuse follicle centre lymphoma	0.620	0.380
C82.4 Follicular lymphoma grade IIIb	0.620	0.380
C82.3 Follicular lymphoma grade IIIa	0.620	0.380
C82.2 Large cell, follicular	0.620	0.380
C82.0 Small cleaved cell, follicular	0.620	0.380
T88.6 Anaphylactic shock due to adverse effect of correct drug or medicament properly administered	0.619	0.381
T83.4 Mechanical complication of other prosthetic devices, implants and grafts in genital tract	0.619	0.381
S39.8 Other specified injuries of abdomen, lower back and pelvis	0.619	0.381
S39.7 Other multiple injuries of abdomen, lower back and pelvis	0.619	0.381
S39.6 Injury of intra-abdominal organ(s) with pelvic organ(s)	0.619	0.381
S39.0 Injury of muscle and tendon of abdomen, lower back and pelvis	0.619	0.381
C90 Multiple myeloma and malignant plasma cell neoplasms	0.618	0.382
S64.0 Injury of ulnar nerve at wrist and hand level	0.618	0.382
D68.0 Von Willebrand's disease	0.617	0.382
D37.4 Colon	0.617	0.383
S46 Injury of muscle and tendon at shoulder and upper arm level	0.617	0.383
F30.9 Manic episode, unspecified	0.617	0.383
F30.8 Other manic episodes	0.617	0.383
F30.2 Mania with psychotic symptoms	0.617	0.383
F30.1 Mania without psychotic symptoms	0.617	0.383
G91 Hydrocephalus	0.616	0.384
S98 Traumatic amputation of ankle and foot	0.616	0.384
S97 Crushing injury of ankle and foot	0.616	0.384
S96 Injury of muscle and tendon at ankle and foot level	0.616	0.384
S95 Injury of blood vessels at ankle and foot level	0.616	0.384
S94 Injury of nerves at ankle and foot level	0.616	0.384
T63 Toxic effect of contact with venomous animals	0.615	0.385
M73 Soft tissue disorders in diseases classified elsewhere	0.615	0.385
S30.9 Superficial injury of abdomen, lower back and pelvis, part unspecified	0.615	0.385
S30.7 Multiple superficial injuries of abdomen, lower back and pelvis	0.615	0.385
S48 Traumatic amputation of shoulder and upper arm	0.614	0.386
S45 Injury of blood vessels at shoulder and upper arm level	0.614	0.386
S44 Injury of nerves at shoulder and upper arm level	0.614	0.386
S41 Open wound of shoulder and upper arm	0.614	0.386
S47 Crushing injury of shoulder and upper arm	0.614	0.386
T83.3 Mechanical complication of intra-uterine contraceptive device	0.613	0.387
Q60-Q64 Congenital malformations of the urinary system	0.613	0.387
C34.0 Main bronchus	0.613	0.387

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations