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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs550513
log Bayes Factor = 27.78
Chromosome 6   position 31,920,687  (GRCh37) Explore rs550513 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.000 1.000
E03.9 Hypothyroidism, unspecified
0.000 0.000 1.000
E10.9 Without complications
0.000 0.000 1.000
M06.9 Rheumatoid arthritis, unspecified
0.000 0.000 1.000
E10 Insulin-dependent diabetes mellitus
0.000 0.000 1.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.000 1.000
E10-E14 Diabetes mellitus
0.000 0.000 1.000
E00-E07 Disorders of thyroid gland
0.000 0.000 1.000
E03 Other hypothyroidism
0.000 0.000 1.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.000 0.000 1.000
E05 Thyrotoxicosis [hyperthyroidism]
0.000 0.002 0.998
E10.3 With ophthalmic complications
0.000 0.006 0.994
E11 Non-insulin-dependent diabetes mellitus
0.000 0.006 0.994
E11.3 With ophthalmic complications
0.000 0.026 0.974
E05.9 Thyrotoxicosis, unspecified
0.000 0.028 0.972
E10.1 With ketoacidosis
0.000 0.048 0.952
E05.0 Thyrotoxicosis with diffuse goitre
0.000 0.050 0.950
E65-E68 Obesity and other hyperalimentation
0.000 0.051 0.949
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.000 0.059 0.941
E66 Obesity
0.000 0.090 0.910
E66.8 Other obesity
0.000 0.095 0.905
E11.9 Without complications
0.000 0.100 0.900
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.000 0.116 0.884
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.134 0.866
E10.5 With peripheral circulatory complications
0.000 0.135 0.865
E11.5 With peripheral circulatory complications
0.000 0.140 0.860
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.150 0.850
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.159 0.840
E10.4 With neurological complications
0.000 0.179 0.821
E11.2 With renal complications
0.000 0.185 0.815
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.000 0.192 0.808
M06 Other rheumatoid arthritis
0.000 0.195 0.805
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.000 0.199 0.801
E06 Thyroiditis
0.000 0.228 0.772
E10.2 With renal complications
0.000 0.233 0.767
E11.6 With other specified complications
0.000 0.258 0.742
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.000 0.260 0.740
M06.0 Seronegative rheumatoid arthritis
0.000 0.274 0.726
M06.98 Rheumatoid arthritis, unspecified (Other)
0.000 0.283 0.717
E10.7 With multiple complications
0.000 0.283 0.717
E10.6 With other specified complications
0.000 0.283 0.717
E10.0 With coma
0.000 0.283 0.717
E12 Malnutrition-related diabetes mellitus
0.000 0.283 0.717
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.283 0.717
E00 Congenital iodine-deficiency syndrome
0.000 0.283 0.717
E02 Subclinical iodine-deficiency hypothyroidism
0.000 0.283 0.717
E03.5 Myxoedema coma
0.000 0.283 0.717
E03.4 Atrophy of thyroid (acquired)
0.000 0.283 0.717
E03.3 Postinfectious hypothyroidism
0.000 0.283 0.717
E03.1 Congenital hypothyroidism without goitre
0.000 0.283 0.717
E03.0 Congenital hypothyroidism with diffuse goitre
0.000 0.283 0.717
E50-E64 Other nutritional deficiencies
0.000 0.283 0.717
E05.8 Other thyrotoxicosis
0.000 0.285 0.715
E05.5 Thyroid crisis or storm
0.000 0.285 0.715
E05.4 Thyrotoxicosis factitia
0.000 0.285 0.715
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.000 0.285 0.715
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.000 0.285 0.715
E11.7 With multiple complications
0.000 0.287 0.713
E11.0 With coma
0.000 0.290 0.710
E13 Other specified diabetes mellitus
0.000 0.298 0.702
E65 Localised adiposity
0.000 0.301 0.699
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.000 0.309 0.691
E67 Other hyperalimentation
0.000 0.319 0.680
E68 Sequelae of hyperalimentation
0.000 0.319 0.680
E10.8 With unspecified complications
0.000 0.333 0.667
E66.1 Drug-induced obesity
0.000 0.347 0.653
E14 Unspecified diabetes mellitus
0.000 0.352 0.648
E11.4 With neurological complications
0.000 0.353 0.646
E40-E46 Malnutrition
0.000 0.359 0.641
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.000 0.370 0.630
E11.8 With unspecified complications
0.000 0.370 0.630
M06.00 Seronegative rheumatoid arthritis (Multiple sites)
0.000 0.374 0.626
E66.2 Extreme obesity with alveolar hypoventilation
0.000 0.374 0.626
E11.1 With ketoacidosis
0.000 0.377 0.623
E06.3 Autoimmune thyroiditis
0.000 0.383 0.617
M06.3 Rheumatoid nodule
0.000 0.384 0.616
E66.0 Obesity due to excess calories
0.000 0.386 0.613
M06.09 Seronegative rheumatoid arthritis (Site unspecified)
0.000 0.391 0.609
M06.8 Other specified rheumatoid arthritis
0.000 0.423 0.577
M06.2 Rheumatoid bursitis
0.000 0.423 0.577
M06.1 Adult-onset Still's disease
0.000 0.423 0.577
E06.5 Other chronic thyroiditis
0.000 0.446 0.554
E06.4 Drug-induced thyroiditis
0.000 0.446 0.554
E06.2 Chronic thyroiditis with transient thyrotoxicosis
0.000 0.446 0.554
E06.1 Subacute thyroiditis
0.000 0.446 0.554
E06.0 Acute thyroiditis
0.000 0.446 0.554
E06.9 Thyroiditis, unspecified
0.000 0.457 0.543
E20-E35 Disorders of other endocrine glands
0.000 0.473 0.527
E53 Deficiency of other B group vitamins
0.000 0.476 0.524
M06.08 Seronegative rheumatoid arthritis (Other)
0.000 0.479 0.520
M06.07 Seronegative rheumatoid arthritis (Ankle and foot)
0.000 0.479 0.520
M06.06 Seronegative rheumatoid arthritis (Lower leg)
0.000 0.479 0.520
M06.05 Seronegative rheumatoid arthritis (Pelvic region and thigh)
0.000 0.479 0.520
M06.04 Seronegative rheumatoid arthritis (Hand)
0.000 0.479 0.520
M06.03 Seronegative rheumatoid arthritis (Forearm)
0.000 0.479 0.520
M06.02 Seronegative rheumatoid arthritis (Upper arm)
0.000 0.479 0.520
M06.01 Seronegative rheumatoid arthritis (Shoulder region)
0.000 0.479 0.520
M06.4 Inflammatory polyarthropathy
0.000 0.483 0.516
E12.9 Without complications
0.000 0.486 0.514
E12.8 With unspecified complications
0.000 0.486 0.514
E12.7 With multiple complications
0.000 0.486 0.514
E12.6 With other specified complications
0.000 0.486 0.514
E12.5 With peripheral circulatory complications
0.000 0.486 0.514
E12.4 With neurological complications
0.000 0.486 0.514
E12.3 With ophthalmic complications
0.000 0.486 0.514
E12.2 With renal complications
0.000 0.486 0.514
E12.1 With ketoacidosis
0.000 0.486 0.514
E12.0 With coma
0.000 0.486 0.514
E00.9 Congenital iodine-deficiency syndrome, unspecified
0.000 0.486 0.514
E00.2 Congenital iodine-deficiency syndrome, mixed type
0.000 0.486 0.514
E00.1 Congenital iodine-deficiency syndrome, myxoedematous type
0.000 0.486 0.514
E00.0 Congenital iodine-deficiency syndrome, neurological type
0.000 0.486 0.514
E01.8 Other iodine-deficiency-related thyroid disorders and allied conditions
0.000 0.486 0.514
E01.2 Iodine-deficiency-related (endemic) goitre, unspecified
0.000 0.486 0.514
E01.1 Iodine-deficiency-related multinodular (endemic) goitre
0.000 0.486 0.514
E01.0 Iodine-deficiency-related diffuse (endemic) goitre
0.000 0.486 0.514
E64 Sequelae of malnutrition and other nutritional deficiencies
0.000 0.486 0.514
E63 Other nutritional deficiencies
0.000 0.486 0.514
E56 Other vitamin deficiencies
0.000 0.486 0.514
E51 Thiamine deficiency
0.000 0.486 0.514
E50 Vitamin A deficiency
0.000 0.486 0.514
E60 Dietary zinc deficiency
0.000 0.486 0.514
E59 Dietary selenium deficiency
0.000 0.486 0.514
E58 Dietary calcium deficiency
0.000 0.486 0.514
E54 Ascorbic acid deficiency
0.000 0.486 0.514
E52 Niacin deficiency [pellagra]
0.000 0.486 0.514
E55 Vitamin D deficiency
0.000 0.486 0.513
E14.3 With ophthalmic complications
0.000 0.490 0.510
E61 Deficiency of other nutrient elements
0.000 0.496 0.504
E13.8 With unspecified complications
0.000 0.496 0.503
E13.7 With multiple complications
0.000 0.496 0.503
E13.6 With other specified complications
0.000 0.496 0.503
E13.5 With peripheral circulatory complications
0.000 0.496 0.503
E13.4 With neurological complications
0.000 0.496 0.503
E13.3 With ophthalmic complications
0.000 0.496 0.503
E13.2 With renal complications
0.000 0.496 0.503
E13.1 With ketoacidosis
0.000 0.496 0.503
E13.0 With coma
0.000 0.496 0.503
E15 Nondiabetic hypoglycaemic coma
0.000 0.504 0.495
E13.9 Without complications
0.000 0.511 0.488
E67.8 Other specified hyperalimentation
0.000 0.512 0.488
E67.3 Hypervitaminosis D
0.000 0.512 0.488
E67.2 Megavitamin-B6 syndrome
0.000 0.512 0.488
E67.1 Hypercarotenaemia
0.000 0.512 0.488
E67.0 Hypervitaminosis A
0.000 0.512 0.488
E03.8 Other specified hypothyroidism
0.001 0.512 0.487
E27 Other disorders of adrenal gland
0.000 0.516 0.484
M06.34 Rheumatoid nodule (Hand)
0.000 0.519 0.480
E16 Other disorders of pancreatic internal secretion
0.000 0.530 0.470
E07 Other disorders of thyroid
0.000 0.531 0.469
E14.8 With unspecified complications
0.000 0.535 0.464
E14.7 With multiple complications
0.000 0.535 0.464
E14.6 With other specified complications
0.000 0.535 0.464
E14.5 With peripheral circulatory complications
0.000 0.535 0.464
E14.4 With neurological complications
0.000 0.535 0.464
E14.1 With ketoacidosis
0.000 0.535 0.464
E14.0 With coma
0.000 0.535 0.464
E44 Protein-energy malnutrition of moderate and mild degree
0.000 0.540 0.460
E45 Retarded development following protein-energy malnutrition
0.000 0.540 0.460
E43 Unspecified severe protein-energy malnutrition
0.000 0.540 0.460
E42 Marasmic kwashiorkor
0.000 0.540 0.460
E41 Nutritional marasmus
0.000 0.540 0.460
E40 Kwashiorkor
0.000 0.540 0.460
M06.39 Rheumatoid nodule (Site unspecified)
0.000 0.558 0.442
M06.38 Rheumatoid nodule (Other)
0.000 0.558 0.442
M06.37 Rheumatoid nodule (Ankle and foot)
0.000 0.558 0.442
M06.36 Rheumatoid nodule (Lower leg)
0.000 0.558 0.442
M06.35 Rheumatoid nodule (Pelvic region and thigh)
0.000 0.558 0.442
M06.33 Rheumatoid nodule (Forearm)
0.000 0.558 0.442
M06.32 Rheumatoid nodule (Upper arm)
0.000 0.558 0.442
M06.31 Rheumatoid nodule (Shoulder region)
0.000 0.558 0.442
M06.30 Rheumatoid nodule (Multiple sites)
0.000 0.558 0.442
E27.1 Primary adrenocortical insufficiency
0.000 0.573 0.427
M05-M14 Inflammatory polyarthropathies
0.001 0.577 0.422
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.000 0.579 0.421
E14.9 Without complications
0.000 0.586 0.414
M06.19 Adult-onset Still's disease (Site unspecified)
0.000 0.586 0.414
M06.18 Adult-onset Still's disease (Other)
0.000 0.586 0.414
M06.17 Adult-onset Still's disease (Ankle and foot)
0.000 0.586 0.414
M06.16 Adult-onset Still's disease (Lower leg)
0.000 0.586 0.414
M06.15 Adult-onset Still's disease (Pelvic region and thigh)
0.000 0.586 0.414
M06.14 Adult-onset Still's disease (Hand)
0.000 0.586 0.414
M06.13 Adult-onset Still's disease (Forearm)
0.000 0.586 0.414
M06.12 Adult-onset Still's disease (Upper arm)
0.000 0.586 0.414
M06.11 Adult-onset Still's disease (Shoulder region)
0.000 0.586 0.414
M06.10 Adult-onset Still's disease (Multiple sites)
0.000 0.586 0.414
M06.29 Rheumatoid bursitis (Site unspecified)
0.000 0.586 0.414
M06.28 Rheumatoid bursitis (Other)
0.000 0.586 0.414
M06.27 Rheumatoid bursitis (Ankle and foot)
0.000 0.586 0.414
M06.26 Rheumatoid bursitis (Lower leg)
0.000 0.586 0.414
M06.25 Rheumatoid bursitis (Pelvic region and thigh)
0.000 0.586 0.414
M06.24 Rheumatoid bursitis (Hand)
0.000 0.586 0.414
M06.23 Rheumatoid bursitis (Forearm)
0.000 0.586 0.414
M06.22 Rheumatoid bursitis (Upper arm)
0.000 0.586 0.414
M06.21 Rheumatoid bursitis (Shoulder region)
0.000 0.586 0.414
M06.20 Rheumatoid bursitis (Multiple sites)
0.000 0.586 0.414
M06.89 Other specified rheumatoid arthritis (Site unspecified)
0.000 0.586 0.414
M06.88 Other specified rheumatoid arthritis (Other)
0.000 0.586 0.414
M06.87 Other specified rheumatoid arthritis (Ankle and foot)
0.000 0.586 0.414
M06.86 Other specified rheumatoid arthritis (Lower leg)
0.000 0.586 0.414
M06.85 Other specified rheumatoid arthritis (Pelvic region and thigh)
0.000 0.586 0.414
M06.84 Other specified rheumatoid arthritis (Hand)
0.000 0.586 0.414
M06.83 Other specified rheumatoid arthritis (Forearm)
0.000 0.586 0.414
M06.82 Other specified rheumatoid arthritis (Upper arm)
0.000 0.586 0.414
M06.81 Other specified rheumatoid arthritis (Shoulder region)
0.000 0.586 0.414
M06.80 Other specified rheumatoid arthritis (Multiple sites)
0.000 0.586 0.414
E20 Hypoparathyroidism
0.000 0.586 0.414
E27.8 Other specified disorders of adrenal gland
0.000 0.592 0.408
E53.8 Deficiency of other specified B group vitamins
0.000 0.596 0.404
E04 Other non-toxic goitre
0.000 0.600 0.400
E27.4 Other and unspecified adrenocortical insufficiency
0.000 0.605 0.395
E22 Hyperfunction of pituitary gland
0.000 0.605 0.395
E46 Unspecified protein-energy malnutrition
0.000 0.615 0.384
E14.2 Withrenal complications
0.000 0.615 0.384
E35 Disorders of endocrine glands in diseases classified elsewhere
0.000 0.622 0.378
E32 Diseases of thymus
0.000 0.622 0.378
E31 Polyglandular dysfunction
0.000 0.622 0.378
E30 Disorders of puberty, not elsewhere classified
0.000 0.622 0.378
E53.1 Pyridoxine deficiency
0.000 0.624 0.376
E53.0 Riboflavin deficiency
0.000 0.624 0.376
M05 Seropositive rheumatoid arthritis
0.001 0.627 0.373
M06.48 Inflammatory polyarthropathy (Other)
0.000 0.629 0.370
M06.47 Inflammatory polyarthropathy (Ankle and foot)
0.000 0.629 0.370
M06.46 Inflammatory polyarthropathy (Lower leg)
0.000 0.629 0.370
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)
0.000 0.629 0.370
M06.44 Inflammatory polyarthropathy (Hand)
0.000 0.629 0.370
M06.43 Inflammatory polyarthropathy (Forearm)
0.000 0.629 0.370
M06.42 Inflammatory polyarthropathy (Upper arm)
0.000 0.629 0.370
M06.41 Inflammatory polyarthropathy (Shoulder region)
0.000 0.629 0.370
M06.40 Inflammatory polyarthropathy (Multiple sites)
0.000 0.629 0.370
E50.9 Vitamin A deficiency, unspecified
0.000 0.631 0.368
E50.8 Other manifestations of vitamin A deficiency
0.000 0.631 0.368
E50.7 Other ocular manifestations of vitamin A deficiency
0.000 0.631 0.368
E50.6 Vitamin A deficiency with xerophthalmic scars of cornea
0.000 0.631 0.368
E50.5 Vitamin A deficiency with night blindness
0.000 0.631 0.368
E50.4 Vitamin A deficiency with keratomalacia
0.000 0.631 0.368
E50.3 Vitamin A deficiency with corneal ulceration and xerosis
0.000 0.631 0.368
E50.2 Vitamin A deficiency with corneal xerosis
0.000 0.631 0.368
E50.1 Vitamin A deficiency with Bitot's spot and conjunctival xerosis
0.000 0.631 0.368
E50.0 Vitamin A deficiency with conjunctival xerosis
0.000 0.631 0.368
E51.9 Thiamine deficiency, unspecified
0.000 0.631 0.368
E51.8 Other manifestations of thiamine deficiency
0.000 0.631 0.368
E51.2 Wernicke's encephalopathy
0.000 0.631 0.368
E51.1 Beriberi
0.000 0.631 0.368
E56.9 Vitamin deficiency, unspecified
0.000 0.631 0.368
E56.8 Deficiency of other vitamins
0.000 0.631 0.368
E56.1 Deficiency of vitamin K
0.000 0.631 0.368
E56.0 Deficiency of vitamin E
0.000 0.631 0.368
E63.9 Nutritional deficiency, unspecified
0.000 0.631 0.368
E63.8 Other specified nutritional deficiencies
0.000 0.631 0.368
E63.1 Imbalance of constituents of food intake
0.000 0.631 0.368
E63.0 Essential fatty acid [EFA] deficiency
0.000 0.631 0.368
E64.9 Sequelae of unspecified nutritional deficiency
0.000 0.631 0.368
E64.8 Sequelae of other nutritional deficiencies
0.000 0.631 0.368
E64.3 Sequelae of rickets
0.000 0.631 0.368
E64.2 Sequelae of vitamin C deficiency
0.000 0.631 0.368
E64.1 Sequelae of vitamin A deficiency
0.000 0.631 0.368
E64.0 Sequelae of protein-energy malnutrition
0.000 0.631 0.368
E55.0 Rickets, active
0.000 0.632 0.368
E55.9 Vitamin D deficiency, unspecified
0.000 0.632 0.368
E27.2 Addisonian crisis
0.000 0.634 0.366
E61.9 Deficiency of nutrient element, unspecified
0.000 0.639 0.361
E61.8 Deficiency of other specified nutrient elements
0.000 0.639 0.361
E61.7 Deficiency of multiple nutrient elements
0.000 0.639 0.361
E61.6 Vanadium deficiency
0.000 0.639 0.361
E61.5 Molybdenum deficiency
0.000 0.639 0.361
E61.4 Chromium deficiency
0.000 0.639 0.361
E61.3 Manganese deficiency
0.000 0.639 0.361
E61.2 Magnesium deficiency
0.000 0.639 0.361
E61.0 Copper deficiency
0.000 0.639 0.361
M07 Psoriatic and enteropathic arthropathies
0.001 0.643 0.356
E21.3 Hyperparathyroidism, unspecified
0.000 0.646 0.354
E53.9 Vitamin B deficiency, unspecified
0.000 0.646 0.354
E61.1 Iron deficiency
0.000 0.649 0.351
E27.5 Adrenomedullary hyperfunction
0.000 0.653 0.347
E27.3 Drug-induced adrenocortical insufficiency
0.000 0.653 0.347
E27.0 Other adrenocortical overactivity
0.000 0.653 0.347
E28 Ovarian dysfunction
0.000 0.657 0.343
E16.0 Drug-induced hypoglycaemia without coma
0.000 0.660 0.340
L40.9 Psoriasis, unspecified
0.000 0.660 0.340
L40 Psoriasis
0.000 0.661 0.339
L40.5 Arthropathic psoriasis
0.000 0.662 0.338
M05.9 Seropositive rheumatoid arthritis, unspecified
0.000 0.662 0.338
E16.9 Disorder of pancreatic internal secretion, unspecified
0.000 0.663 0.337
E16.8 Other specified disorders of pancreatic internal secretion
0.000 0.663 0.337
E16.4 Abnormal secretion of gastrin
0.000 0.663 0.337
E16.3 Increased secretion of glucagon
0.000 0.663 0.337
E07.1 Dyshormogenetic goitre
0.000 0.663 0.336
E07.0 Hypersecretion of calcitonin
0.000 0.663 0.336
E16.2 Hypoglycaemia, unspecified
0.000 0.667 0.333
E20.9 Hypoparathyroidism, unspecified
0.000 0.668 0.332
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.000 0.669 0.331
E44.1 Mild protein-energy malnutrition
0.000 0.670 0.330
E44.0 Moderate protein-energy malnutrition
0.000 0.670 0.330
E26 Hyperaldosteronism
0.000 0.671 0.328
E22.1 Hyperprolactinaemia
0.000 0.682 0.318
E04.0 Non-toxic diffuse goitre
0.000 0.684 0.316
M14 Arthropathies in other diseases classified elsewhere
0.001 0.686 0.313
E16.1 Other hypoglycaemia
0.000 0.688 0.311
M06.49 Inflammatory polyarthropathy (Site unspecified)
0.001 0.690 0.310
E25 Adrenogenital disorders
0.001 0.690 0.309
M07.3 Other psoriatic arthropathies
0.000 0.691 0.309
E24 Cushing's syndrome
0.000 0.691 0.309
E07.8 Other specified disorders of thyroid
0.001 0.694 0.305
M12 Other specific arthropathies
0.001 0.697 0.302
M09 Juvenile arthritis in diseases classified elsewhere
0.001 0.697 0.302
M08 Juvenile arthritis
0.001 0.697 0.302
E21.5 Disorder of parathyroid gland, unspecified
0.000 0.698 0.302
E21.4 Other specified disorders of parathyroid gland
0.000 0.698 0.302
E21.2 Other hyperparathyroidism
0.000 0.698 0.302
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.000 0.699 0.301
E29 Testicular dysfunction
0.000 0.700 0.299
E04.2 Non-toxic multinodular goitre
0.000 0.703 0.297
E20.8 Other hypoparathyroidism
0.000 0.703 0.297
E20.1 Pseudohypoparathyroidism
0.000 0.703 0.297
E20.0 Idiopathic hypoparathyroidism
0.000 0.703 0.297
S61.0 Open wound of finger(s) without damage to nail
0.287 0.713 0.000
E04.8 Other specified non-toxic goitre
0.000 0.713 0.287
E23 Hypofunction and other disorders of pituitary gland
0.000 0.714 0.285
L40.0 Psoriasis vulgaris
0.000 0.715 0.285
E22.9 Hyperfunction of pituitary gland, unspecified
0.000 0.717 0.283
E22.8 Other hyperfunction of pituitary gland
0.000 0.717 0.283
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.000 0.719 0.281
M11 Other crystal arthropathies
0.001 0.720 0.278
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.000 0.721 0.279
E30.9 Disorder of puberty, unspecified
0.000 0.729 0.271
E30.8 Other disorders of puberty
0.000 0.729 0.271
E30.1 Precocious puberty
0.000 0.729 0.271
E30.0 Delayed puberty
0.000 0.729 0.271
E31.9 Polyglandular dysfunction, unspecified
0.000 0.729 0.271
E31.8 Other polyglandular dysfunction
0.000 0.729 0.271
E31.1 Polyglandular hyperfunction
0.000 0.729 0.271
E31.0 Autoimmune polyglandular failure
0.000 0.729 0.271
E32.9 Disease of thymus, unspecified
0.000 0.729 0.271
E32.8 Other diseases of thymus
0.000 0.729 0.271
E32.1 Abscess of thymus
0.000 0.729 0.271
E32.0 Persistent hyperplasia of thymus
0.000 0.729 0.271
E35.8 Disorders of other endocrine glands in diseases classified elsewhere
0.000 0.729 0.271
E35.1 Disorders of adrenal glands in diseases classified elsewhere
0.000 0.729 0.271
E35.0 Disorders of thyroid gland in diseases classified elsewhere
0.000 0.729 0.271
M05.8 Other seropositive rheumatoid arthritis
0.001 0.732 0.267
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.001 0.732 0.267
M05.2 Rheumatoid vasculitis
0.001 0.732 0.267
M05.1 Rheumatoid lung disease
0.001 0.732 0.267
M05.0 Felty's syndrome
0.001 0.732 0.267
E22.0 Acromegaly and pituitary gigantism
0.000 0.739 0.261
M07.39 Other psoriatic arthropathies (Site unspecified)
0.000 0.742 0.258
M07.6 Other enteropathic arthropathies
0.001 0.744 0.255
M07.5 Arthropathy in ulcerative colitis
0.001 0.744 0.255
M07.4 Arthropathy in Crohn's disease [regional enteritis]
0.001 0.744 0.255
M07.2 Psoriatic spondylitis
0.001 0.744 0.255
M07.1 Arthritis mutilans
0.001 0.744 0.255
M07.0 Distal interphalangeal psoriatic arthropathy
0.001 0.744 0.255
M10 Gout
0.001 0.745 0.254
E34 Other endocrine disorders
0.001 0.746 0.253
M07.30 Other psoriatic arthropathies (Multiple sites)
0.000 0.749 0.251
L40.8 Other psoriasis
0.000 0.750 0.250
E27.9 Disorder of adrenal gland, unspecified
0.000 0.754 0.246
E28.9 Ovarian dysfunction, unspecified
0.000 0.754 0.246
E28.8 Other ovarian dysfunction
0.000 0.754 0.246
E28.3 Primary ovarian failure
0.000 0.754 0.246
E28.1 Androgen excess
0.000 0.754 0.246
E28.0 Oestrogen excess
0.000 0.754 0.246
L40.4 Guttate psoriasis
0.000 0.757 0.243
L40.3 Pustulosis palmaris et plantaris
0.000 0.757 0.243
L40.2 Acrodermatitis continua
0.000 0.757 0.243
L40.1 Generalised pustular psoriasis
0.000 0.757 0.243
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)
0.000 0.758 0.242
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)
0.000 0.758 0.242
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.000 0.758 0.242
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)
0.000 0.758 0.242
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)
0.000 0.758 0.242
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)
0.000 0.758 0.242
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)
0.000 0.758 0.242
E21.0 Primary hyperparathyroidism
0.000 0.761 0.239
E26.9 Hyperaldosteronism, unspecified
0.000 0.764 0.235
E26.8 Other hyperaldosteronism
0.000 0.764 0.235
E26.1 Secondary hyperaldosteronism
0.000 0.764 0.235
M14.6 Neuropathic arthropathy
0.001 0.764 0.235
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)
0.000 0.772 0.228
M14.8 Arthropathies in other specified diseases classified elsewhere
0.001 0.775 0.224
M14.5 Arthropathies in other endocrine, nutritional and metabolic disorders
0.001 0.775 0.224
M14.4 Arthropathy in amyloidosis
0.001 0.775 0.224
M14.3 Lipoid dermatoarthritis
0.001 0.775 0.224
M14.2 Diabetic arthropathy
0.001 0.775 0.224
M14.1 Crystal arthropathy in other metabolic disorders
0.001 0.775 0.224
M14.0 Gouty arthropathy due to enzyme defects and other inherited disorders
0.001 0.775 0.224
S61 Open wound of wrist and hand
0.222 0.778 0.000
E25.9 Adrenogenital disorder, unspecified
0.001 0.778 0.222
E25.8 Other adrenogenital disorders
0.001 0.778 0.222
M07.38 Other psoriatic arthropathies (Other)
0.000 0.778 0.221
M07.37 Other psoriatic arthropathies (Ankle and foot)
0.000 0.778 0.221
M07.36 Other psoriatic arthropathies (Lower leg)
0.000 0.778 0.221
M07.35 Other psoriatic arthropathies (Pelvic region and thigh)
0.000 0.778 0.221
M07.34 Other psoriatic arthropathies (Hand)
0.000 0.778 0.221
M07.33 Other psoriatic arthropathies (Forearm)
0.000 0.778 0.221
M07.32 Other psoriatic arthropathies (Upper arm)
0.000 0.778 0.221
M07.31 Other psoriatic arthropathies (Shoulder region)
0.000 0.778 0.221
E24.8 Other Cushing's syndrome
0.000 0.778 0.221
E24.4 Alcohol-induced pseudo-Cushing's syndrome
0.000 0.778 0.221
E24.3 Ectopic ACTH syndrome
0.000 0.778 0.221
E24.2 Drug-induced Cushing's syndrome
0.000 0.778 0.221
E24.1 Nelson's syndrome
0.000 0.778 0.221
E24.0 Pituitary-dependent Cushing's disease
0.000 0.778 0.221
M08.9 Juvenile arthritis, unspecified
0.001 0.782 0.217
M08.8 Other juvenile arthritis
0.001 0.782 0.217
M08.4 Pauciarticular juvenile arthritis
0.001 0.782 0.217
M08.3 Juvenile polyarthritis (seronegative)
0.001 0.782 0.217
M08.2 Juvenile arthritis with systemic onset
0.001 0.782 0.217
M08.1 Juvenile ankylosing spondylitis
0.001 0.782 0.217
M08.0 Juvenile rheumatoid arthritis
0.001 0.782 0.217
M09.8 Juvenile arthritis in other diseases classified elsewhere
0.001 0.782 0.217
M09.2 Juvenile arthritis in ulcerative colitis
0.001 0.782 0.217
M09.1 Juvenile arthritis in Crohn's disease [regional enteritis]
0.001 0.782 0.217
M09.0 Juvenile arthritis in psoriasis
0.001 0.782 0.217
M12.8 Other specific arthropathies, not elsewhere classified
0.001 0.782 0.217
M12.5 Traumatic arthropathy
0.001 0.782 0.217
M12.4 Intermittent hydrarthrosis
0.001 0.782 0.217
M12.3 Palindromic rheumatism
0.001 0.782 0.217
M12.2 Villonodular synovitis (pigmented)
0.001 0.782 0.217
M12.1 Kaschin-Beck disease
0.001 0.782 0.217
M12.0 Chronic postrheumatic arthropathy [Jaccoud]
0.001 0.782 0.217
E29.9 Testicular dysfunction, unspecified
0.000 0.785 0.215
E29.8 Other testicular dysfunction
0.000 0.785 0.215
E29.0 Testicular hyperfunction
0.000 0.785 0.215
L40-L45 Papulosquamous disorders
0.000 0.787 0.213
E28.2 Polycystic ovarian syndrome
0.000 0.789 0.211
S61.1 Open wound of finger(s) with damage to nail
0.209 0.791 0.000
E23.7 Disorder of pituitary gland, unspecified
0.000 0.794 0.206
E23.3 Hypothalamic dysfunction, not elsewhere classified
0.000 0.795 0.205
E23.1 Drug-induced hypopituitarism
0.000 0.795 0.205
M11.9 Crystal arthropathy, unspecified
0.001 0.799 0.200
M11.8 Other specified crystal arthropathies
0.001 0.799 0.200
M11.1 Familial chondrocalcinosis
0.001 0.799 0.200
M11.0 Hydroxyapatite deposition disease
0.001 0.799 0.200
E23.2 Diabetes insipidus
0.000 0.802 0.198
M13 Other arthritis
0.001 0.807 0.192
M05.09 Felty's syndrome (Site unspecified)
0.001 0.808 0.192
M05.08 Felty's syndrome (Other)
0.001 0.808 0.192
M05.07 Felty's syndrome (Ankle and foot)
0.001 0.808 0.192
M05.06 Felty's syndrome (Lower leg)
0.001 0.808 0.192
M05.05 Felty's syndrome (Pelvic region and thigh)
0.001 0.808 0.192
M05.04 Felty's syndrome (Hand)
0.001 0.808 0.192
M05.03 Felty's syndrome (Forearm)
0.001 0.808 0.192
M05.02 Felty's syndrome (Upper arm)
0.001 0.808 0.192
M05.01 Felty's syndrome (Shoulder region)
0.001 0.808 0.192
M05.00 Felty's syndrome (Multiple sites)
0.001 0.808 0.192
M05.19 Rheumatoid lung disease (Site unspecified)
0.001 0.808 0.192
M05.18 Rheumatoid lung disease (Other)
0.001 0.808 0.192
M05.17 Rheumatoid lung disease (Ankle and foot)
0.001 0.808 0.192
M05.16 Rheumatoid lung disease (Lower leg)
0.001 0.808 0.192
M05.15 Rheumatoid lung disease (Pelvic region and thigh)
0.001 0.808 0.192
M05.14 Rheumatoid lung disease (Hand)
0.001 0.808 0.192
M05.13 Rheumatoid lung disease (Forearm)
0.001 0.808 0.192
M05.12 Rheumatoid lung disease (Upper arm)
0.001 0.808 0.192
M05.11 Rheumatoid lung disease (Shoulder region)
0.001 0.808 0.192
M05.10 Rheumatoid lung disease (Multiple sites)
0.001 0.808 0.192
M05.29 Rheumatoid vasculitis (Site unspecified)
0.001 0.808 0.192
M05.28 Rheumatoid vasculitis (Other)
0.001 0.808 0.192
M05.27 Rheumatoid vasculitis (Ankle and foot)
0.001 0.808 0.192
M05.26 Rheumatoid vasculitis (Lower leg)
0.001 0.808 0.192
M05.25 Rheumatoid vasculitis (Pelvic region and thigh)
0.001 0.808 0.192
M05.24 Rheumatoid vasculitis (Hand)
0.001 0.808 0.192
M05.23 Rheumatoid vasculitis (Forearm)
0.001 0.808 0.192
M05.22 Rheumatoid vasculitis (Upper arm)
0.001 0.808 0.192
M05.21 Rheumatoid vasculitis (Shoulder region)
0.001 0.808 0.192
M05.20 Rheumatoid vasculitis (Multiple sites)
0.001 0.808 0.192
M05.39 Rheumatoid arthritis with involvement of other organs and systems (Site unspecified)
0.001 0.808 0.192
M05.38 Rheumatoid arthritis with involvement of other organs and systems (Other)
0.001 0.808 0.192
M05.37 Rheumatoid arthritis with involvement of other organs and systems (Ankle and foot)
0.001 0.808 0.192
M05.36 Rheumatoid arthritis with involvement of other organs and systems (Lower leg)
0.001 0.808 0.192
M05.35 Rheumatoid arthritis with involvement of other organs and systems (Pelvic region and thigh)
0.001 0.808 0.192
M05.34 Rheumatoid arthritis with involvement of other organs and systems (Hand)
0.001 0.808 0.192
M05.33 Rheumatoid arthritis with involvement of other organs and systems (Forearm)
0.001 0.808 0.192
M05.32 Rheumatoid arthritis with involvement of other organs and systems (Upper arm)
0.001 0.808 0.192
M05.31 Rheumatoid arthritis with involvement of other organs and systems (Shoulder region)
0.001 0.808 0.192
M05.30 Rheumatoid arthritis with involvement of other organs and systems (Multiple sites)
0.001 0.808 0.192
M05.89 Other seropositive rheumatoid arthritis (Site unspecified)
0.001 0.808 0.192
M05.88 Other seropositive rheumatoid arthritis (Other)
0.001 0.808 0.192
M05.87 Other seropositive rheumatoid arthritis (Ankle and foot)
0.001 0.808 0.192
M05.86 Other seropositive rheumatoid arthritis (Lower leg)
0.001 0.808 0.192
M05.85 Other seropositive rheumatoid arthritis (Pelvic region and thigh)
0.001 0.808 0.192
M05.84 Other seropositive rheumatoid arthritis (Hand)
0.001 0.808 0.192
M05.83 Other seropositive rheumatoid arthritis (Forearm)
0.001 0.808 0.192
M05.82 Other seropositive rheumatoid arthritis (Upper arm)
0.001 0.808 0.192
M05.81 Other seropositive rheumatoid arthritis (Shoulder region)
0.001 0.808 0.192
M05.80 Other seropositive rheumatoid arthritis (Multiple sites)
0.001 0.808 0.192
E26.0 Primary hyperaldosteronism
0.001 0.814 0.186
M07.09 Distal interphalangeal psoriatic arthropathy (Site unspecified)
0.001 0.816 0.183
M07.08 Distal interphalangeal proriatic arthropathy-Other
0.001 0.816 0.183
M07.07 Distal interphalangeal psoriatic arthropathy (Ankle and foot)
0.001 0.816 0.183
M07.06 Distal interphalangeal proriatic arthropathy-Lower leg
0.001 0.816 0.183
M07.05 Distal interphalangeal proriatic arthropathy-Pelvic/thigh
0.001 0.816 0.183
M07.04 Distal interphalangeal psoriatic arthropathy (Hand)
0.001 0.816 0.183
M07.03 Distal interphalangeal proriatic arthropathy-Forearm
0.001 0.816 0.183
M07.02 Distal interphalangeal proriatic arthropathy-Upper arm
0.001 0.816 0.183
M07.01 Distal interphalangeal proriatic arthropathy-Shldr region
0.001 0.816 0.183
M07.00 Distal interphalangeal psoriatic arthropathy (Multiple sites)
0.001 0.816 0.183
M07.19 Arthritis mutilans (Site unspecified)
0.001 0.816 0.183
M07.18 Arthritis mutilans (Other)
0.001 0.816 0.183

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

This website was created, designed, and edited by ORCID iD iconPatrick K. Albers

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