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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs55708186
log Bayes Factor = 6.1979
Chromosome 10   position 134,118,989  (GRCh37) Explore rs55708186 on Ensembl!
Variant rs55708186 is part of Cluster X0084

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
H30-H36 Disorders of choroid and retina
1.000 0.000 0.000
H35 Other retinal disorders
1.000 0.000 0.000
H33 Retinal detachments and breaks
1.000 0.000 0.000
Chapter VII Diseases of the eye and adnexa
0.999 0.001 0.000
# Top node
0.999 0.001 0.000
Chapter XI Diseases of the digestive system
0.999 0.001 0.000
K50-K52 Noninfective enteritis and colitis
0.998 0.002 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.997 0.003 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.997 0.003 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.994 0.006 0.000
K50 Crohn's disease [regional enteritis]
0.994 0.006 0.000
H33.0 Retinal detachment with retinal break
0.994 0.006 0.000
H35.8 Other specified retinal disorders
0.994 0.006 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.990 0.010 0.000
H33.2 Serous retinal detachment
0.986 0.014 0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts
0.986 0.014 0.000
K85 Acute pancreatitis
0.975 0.025 0.000
Chapter V Mental and behavioural disorders
0.961 0.039 0.000
T86 Failure and rejection of transplanted organs and tissues
0.959 0.041 0.000
Chapter XXII Codes for special purposes
0.952 0.048 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.949 0.051 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.949 0.051 0.000
K85.9 Acute pancreatitis, unspecified
0.949 0.051 0.000
H35.3 Degeneration of macula and posterior pole
0.946 0.054 0.000
H35.4 Peripheral retinal degeneration
0.942 0.058 0.000
K50.8 Other Crohn's disease
0.928 0.072 0.000
H34 Retinal vascular occlusions
0.927 0.073 0.000
K51 Ulcerative colitis
0.918 0.082 0.000
K50.9 Crohn's disease, unspecified
0.916 0.084 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.916 0.084 0.000
K50.1 Crohn's disease of large intestine
0.914 0.086 0.000
T85.8 Other complications of internal prosthetic devices, implants and grafts, not elsewhere classified
0.912 0.088 0.000
K55-K64 Other diseases of intestines
0.905 0.095 0.000
T86.8 Failure and rejection of other transplanted organs and tissues
0.904 0.096 0.000
H43-H45 Disorders of vitreous body and globe
0.902 0.098 0.000
K82 Other diseases of gallbladder
0.900 0.100 0.000
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts
0.900 0.100 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.899 0.101 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.896 0.104 0.000
F00 Dementia in Alzheimer's disease
0.895 0.105 0.000
S90-S99 Injuries to the ankle and foot
0.890 0.110 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.889 0.111 0.000
H33.5 Other retinal detachments
0.883 0.117 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.878 0.122 0.000
H34.8 Other retinal vascular occlusions
0.868 0.132 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.864 0.136 0.000
K80 Cholelithiasis
0.863 0.137 0.000
K85.1 Biliary acute pancreatitis
0.862 0.138 0.000
H55-H59 Other disorders of eye and adnexa
0.857 0.143 0.000
K50.0 Crohn's disease of small intestine
0.856 0.144 0.000
U80 Agent resistant to penicillin and related antibiotics
0.855 0.145 0.000
K57 Diverticular disease of intestine
0.851 0.149 0.000
K13 Other diseases of lip and oral mucosa
0.851 0.149 0.000
K86 Other diseases of pancreas
0.847 0.153 0.000
T85.2 Mechanical complication of intraocular lens
0.843 0.157 0.000
K51.4 Pseudopolyposis of colon
0.842 0.158 0.000
E70-E90 Metabolic disorders
0.841 0.159 0.000
K13.7 Other and unspecified lesions of oral mucosa
0.836 0.164 0.000
F00.9 Dementia in Alzheimer's disease, unspecified
0.835 0.165 0.000
E83 Disorders of mineral metabolism
0.833 0.167 0.000
Chapter XX External causes of morbidity and mortality
0.829 0.171 0.000
H10-H13 Disorders of conjunctiva
0.827 0.173 0.000
H35.7 Separation of retinal layers
0.827 0.173 0.000
K62 Other diseases of anus and rectum
0.826 0.174 0.000
K57.9 Diverticular disease of intestine, part unspecified, without perforation or abscess
0.825 0.175 0.000
S10-S19 Injuries to the neck
0.824 0.176 0.000
E83.5 Disorders of calcium metabolism
0.819 0.181 0.000
E20-E35 Disorders of other endocrine glands
0.815 0.185 0.000
U80.1 Methicillin resistant agent
0.814 0.186 0.000
H35.6 Retinal haemorrhage
0.813 0.187 0.000
T66-T78 Other and unspecified effects of external causes
0.811 0.189 0.000
F02 Dementia in other diseases classified elsewhere
0.810 0.190 0.000
F01 Vascular dementia
0.810 0.190 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.808 0.192 0.000
Q80-Q89 Other congenital malformations
0.801 0.199 0.000
S60-S69 Injuries to the wrist and hand
0.800 0.200 0.000
K82.8 Other specified diseases of gallbladder
0.799 0.201 0.000
T82.3 Mechanical complication of other vascular grafts
0.785 0.215 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.783 0.217 0.000
K80.0 Calculus of gallbladder with acute cholecystitis
0.782 0.218 0.000
H43 Disorders of vitreous body
0.781 0.219 0.000
K11 Diseases of salivary glands
0.779 0.221 0.000
K55 Vascular disorders of intestine
0.778 0.222 0.000
H35.9 Retinal disorder, unspecified
0.778 0.222 0.000
T86.0 Bone-marrow transplant rejection
0.774 0.226 0.000
T88.7 Unspecified adverse effect of drug or medicament
0.770 0.230 0.000
T82.0 Mechanical complication of heart valve prosthesis
0.770 0.230 0.000
K62.4 Stenosis of anus and rectum
0.766 0.234 0.000
K62.0 Anal polyp
0.765 0.235 0.000
F03 Unspecified dementia
0.761 0.239 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.761 0.239 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.761 0.239 0.000
K56 Paralytic ileus and intestinal obstruction without hernia
0.761 0.239 0.000
T86.1 Kidney transplant failure and rejection
0.760 0.239 0.000
F60-F69 Disorders of adult personality and behaviour
0.760 0.240 0.000
T87 Complications peculiar to reattachment and amputation
0.759 0.241 0.000
S91 Open wound of ankle and foot
0.755 0.245 0.000
T85.0 Mechanical complication of ventricular intracranial (communicating) shunt
0.755 0.245 0.000
K06 Other disorders of gingiva and edentulous alveolar ridge
0.755 0.245 0.000
H44 Disorders of globe
0.754 0.246 0.000
T85.3 Mechanical complication of other ocular prosthetic devices, imnplants and grafts
0.753 0.247 0.000
K52 Other non-infective gastro-enteritis and colitis
0.752 0.248 0.000
K00 Disorders of tooth development and eruption
0.750 0.250 0.000
K51.0 Ulcerative (chronic) enterocolitis
0.747 0.253 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.746 0.254 0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level
0.743 0.257 0.000
H59 Postprocedural disorders of eye and adnexa, not elsewhere classified
0.741 0.258 0.000
K82.2 Perforation of gallbladder
0.739 0.261 0.000
E83.3 Disorders of phosphorus metabolism
0.738 0.262 0.000
T00-T07 Injuries involving multiple body regions
0.738 0.262 0.000
K80.8 Other cholelithiasis
0.730 0.270 0.000
F00.0 Dementia in Alzheimer's disease with early onset
0.730 0.270 0.000
K80.4 Calculus of bile duct with cholecystitis
0.729 0.271 0.000
T88.4 Failed or difficult intubation
0.727 0.273 0.000
K51.8 Other ulcerative colitis
0.724 0.276 0.000
S68 Traumatic amputation of wrist and hand
0.723 0.277 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.717 0.283 0.000
H31 Other disorders of choroid
0.717 0.283 0.000
H30 Chorioretinal inflammation
0.717 0.283 0.000
H35.1 Retinopathy of prematurity
0.717 0.283 0.000
H33.4 Traction detachment of retina
0.717 0.283 0.000
H33.1 Retinoschisis and retinal cysts
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.716 0.284 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.716 0.284 0.000
T82.1 Mechanical complication of cardiac electronic device
0.716 0.284 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.716 0.284 0.000
K62.3 Rectal prolapse
0.716 0.284 0.000
F06 Other mental disorders due to brain damage and dysfunction and to physical disease
0.715 0.285 0.000
T33-T35 Frostbite
0.715 0.285 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.715 0.285 0.000
T82.9 Unspecified complication of cardiac and vascular prosthetic device, implant and graft
0.713 0.287 0.000
T82.6 Infection and inflammatory reaction due to cardiac valve prosthesis
0.713 0.287 0.000
T82.4 Mechanical complication of vascular dialysis catheter
0.713 0.287 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.713 0.287 0.000
F01.9 Vascular dementia, unspecified
0.710 0.290 0.000
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere
0.710 0.290 0.000
S64 Injury of nerves at wrist and hand level
0.709 0.291 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.709 0.291 0.000
K82.1 Hydrops of gallbladder
0.709 0.291 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.709 0.291 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.707 0.293 0.000
E26 Hyperaldosteronism
0.706 0.294 0.000
F02.8 Dementia in other specified diseases classified elsewhere
0.703 0.297 0.000
K80.1 Calculus of gallbladder with other cholecystitis
0.701 0.299 0.000
H57 Other disorders of eye and adnexa
0.699 0.300 0.000
K85.8 Other acute pancreatitis
0.699 0.301 0.000
K85.3 Drug-induced acute pancreatitis
0.699 0.301 0.000
K85.2 Alcohol-induced acute pancreatitis
0.699 0.301 0.000
K85.0 Idiopathic acute pancreatitis
0.699 0.301 0.000
E40-E46 Malnutrition
0.699 0.301 0.000
T82.2 Mechanical complication of coronary artery bypass and valve grafts
0.699 0.301 0.000
E86 Volume depletion
0.698 0.302 0.000
K51.9 Ulcerative colitis, unspecified
0.698 0.302 0.000
F99-F99 Unspecified mental disorder
0.698 0.302 0.000
H35.2 Other proliferative retinopathy
0.698 0.302 0.000
H34.2 Other retinal artery occlusions
0.697 0.303 0.000
Q85 Phakomatoses, not elsewhere classified
0.696 0.304 0.000
X60-X84 Intentional self-harm
0.693 0.307 0.000
K57.4 Diverticular disease of both small and large intestine with perforation and abscess
0.691 0.309 0.000
H35.5 Hereditary retinal dystrophy
0.691 0.309 0.000
S60 Superficial injury of wrist and hand
0.691 0.309 0.000
U80.0 Penicillin resistant agent
0.691 0.309 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.691 0.309 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.690 0.310 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.689 0.311 0.000
F70-F79 Mental retardation
0.689 0.311 0.000
K56.5 Intestinal adhesions [bands] with obstruction
0.688 0.312 0.000
T86.9 Failure and rejection of unspecified transplanted organ and tissue
0.688 0.312 0.000
T86.4 Liver transplant failure and rejection
0.688 0.312 0.000
T86.3 Heart-lung transplant failure and rejection
0.688 0.312 0.000
T86.2 Heart transplant failure and rejection
0.688 0.312 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.686 0.313 0.000
T85.9 Unspecified complication of internal prosthetic device, implant and graft
0.685 0.315 0.000
T88.6 Anaphylactic shock due to adverse effect of correct drug or medicament properly administered
0.685 0.315 0.000
T36 Poisoning by systemic antibiotics
0.683 0.317 0.000
E83.4 Disorders of magnesium metabolism
0.682 0.318 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.681 0.319 0.000
T85.1 Mechanical complication of implanted electronic stimulator of nervous system
0.681 0.319 0.000
F05 Delirium, not induced by alcohol and other psychoactive substances
0.680 0.319 0.000
F07 Personality and behavioural disorders due to brain disease, damage and dysfunction
0.680 0.320 0.000
F09 Unspecified organic or symptomatic mental disorder
0.680 0.320 0.000
F04 Organic amnesic syndrome, not induced by alcohol and other psychoactive substances
0.680 0.320 0.000
K62.8 Other specified diseases of anus and rectum
0.678 0.322 0.000
T78 Adverse effects, not elsewhere classified
0.678 0.322 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.677 0.322 0.000
U81 Agent resistant to vancomycin and related antibiotics
0.677 0.323 0.000
H11 Other disorders of conjunctiva
0.676 0.324 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.676 0.324 0.000
K86.9 Disease of pancreas, unspecified
0.675 0.325 0.000
K86.1 Other chronic pancreatitis
0.673 0.327 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.671 0.329 0.000
K51.3 Ulcerative (chronic) rectosigmoiditis
0.670 0.330 0.000
F52 Sexual dysfunction, not caused by organic disorder or disease
0.670 0.330 0.000
K14 Diseases of tongue
0.669 0.331 0.000
K57.2 Diverticular disease of large intestine with perforation and abscess
0.669 0.331 0.000
S68.1 Traumatic amputation of other single finger (complete)(partial)
0.667 0.333 0.000
K62.6 Ulcer of anus and rectum
0.667 0.333 0.000
Chapter VIII Diseases of the ear and mastoid process
0.667 0.333 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.666 0.334 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.665 0.334 0.000
E22 Hyperfunction of pituitary gland
0.665 0.335 0.000
K55.2 Angiodysplasia of colon
0.665 0.335 0.000
V20-V29 Motorcycle rider injured in transport accident
0.665 0.335 0.000
H34.9 Retinal vascular occlusion, unspecified
0.665 0.335 0.000
H34.1 Central retinal artery occlusion
0.665 0.335 0.000
H34.0 Transient retinal artery occlusion
0.665 0.335 0.000
K86.8 Other specified diseases of pancreas
0.664 0.336 0.000
Q50-Q56 Congenital malformations of genital organs
0.664 0.336 0.000
T85.4 Mechanical complication of breast prosthesis and implant
0.663 0.337 0.000
S92 Fracture of foot, except ankle
0.661 0.339 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.659 0.341 0.000
H59.8 Other postprocedural disorders of eye and adnexa
0.659 0.341 0.000
K51.1 Ulcerative (chronic) ileocolitis
0.658 0.342 0.000
K06.9 Disorder of gingiva and edentulous alveolar ridge, unspecified
0.658 0.342 0.000
Q00-Q07 Congenital malformations of the nervous system
0.657 0.342 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.657 0.343 0.000
Q35-Q37 Cleft lip and cleft palate
0.657 0.343 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.657 0.343 0.000
K62.2 Anal prolapse
0.656 0.344 0.000
U88 Agent resistant to multiple antibiotics
0.656 0.344 0.000
H58 Other disorders of eye and adnexa in diseases classified elsewhere
0.653 0.347 0.000
K11.2 Sialoadenitis
0.652 0.348 0.000
S14 Injury of nerves and spinal cord at neck level
0.651 0.349 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.650 0.350 0.000
K56.2 Volvulus
0.649 0.351 0.000
K64 Haemorrhoids and perianal venous thrombosis
0.649 0.351 0.000
H43.3 Other vitreous opacities
0.649 0.351 0.000
U51 Admission status on psychiatric patients
0.648 0.352 0.000
T40.6 Other and unspecified narcotics
0.647 0.353 0.000
H45 Disorders of vitreous body and globe in diseases classified elsewhere
0.646 0.353 0.000
K82.3 Fistula of gallbladder
0.645 0.354 0.000
K82.0 Obstruction of gallbladder
0.645 0.354 0.000
U50 Level of care administered to neonates
0.645 0.355 0.000
U07 Emergency use of U07
0.645 0.355 0.000
U06 Emergency use of U06
0.645 0.355 0.000
U04 Severe acute respiratory syndrome [SARS]
0.645 0.355 0.000
U52 First in a series of a regular day/night admissions
0.645 0.355 0.000
H44.2 Degenerative myopia
0.644 0.356 0.000
S90 Superficial injury of ankle and foot
0.642 0.358 0.000
F00.2 Dementia in Alzheimer's disease, atypical or mixed type
0.641 0.358 0.000
F00.1 Dementia in Alzheimer's disease with late onset
0.641 0.358 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.641 0.359 0.000
T79-T79 Certain early complications of trauma
0.639 0.361 0.000
S98 Traumatic amputation of ankle and foot
0.638 0.362 0.000
S97 Crushing injury of ankle and foot
0.638 0.362 0.000
S96 Injury of muscle and tendon at ankle and foot level
0.638 0.362 0.000
S95 Injury of blood vessels at ankle and foot level
0.638 0.362 0.000
S94 Injury of nerves at ankle and foot level
0.638 0.362 0.000
T88.9 Complication of surgical and medical care, unspecified
0.637 0.363 0.000
T88.5 Other complications of anaesthesia
0.637 0.363 0.000
T88.3 Malignant hyperthermia due to anaesthesis
0.637 0.363 0.000
T88.2 Shock due to anaesthesia
0.637 0.363 0.000
T88.1 Other complications following immunisation, not elsewhere classified
0.637 0.363 0.000
T88.0 Infection following immunisation
0.637 0.363 0.000
X20-X29 Contact with venomous animals and plants
0.637 0.363 0.000
K10 Other diseases of jaws
0.636 0.364 0.000
H10 Conjunctivitis
0.636 0.364 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.635 0.365 0.000
S93.0 Dislocation of ankle joint
0.635 0.365 0.000
S65 Injury of blood vessels at wrist and hand level
0.635 0.365 0.000
S60.8 Other superficial injuries of wrist and hand
0.633 0.367 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.633 0.367 0.000
Q18 Other congenital malformations of face and neck
0.633 0.367 0.000
K55.8 Other vascular disorders of intestine
0.632 0.368 0.000
H40-H42 Glaucoma
0.631 0.369 0.000
S13 Dislocation, sprain and strain of joints and ligaments at neck level
0.631 0.369 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.630 0.370 0.000
S91.3 Open wound of other parts of foot
0.630 0.370 0.000
K03 Other diseases of hard tissues of teeth
0.629 0.371 0.000
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts
0.628 0.372 0.000
T40.2 Other opioids
0.628 0.372 0.000
E26.0 Primary hyperaldosteronism
0.627 0.373 0.000
S19 Other and unspecified injuries of neck
0.627 0.373 0.000
K12 Stomatitis and related lesions
0.627 0.373 0.000
F50 Eating disorders
0.626 0.374 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.626 0.374 0.000
F80-F89 Disorders of psychological development
0.626 0.374 0.000
K00.6 Disturbances in tooth eruption
0.625 0.375 0.000
H60-H62 Diseases of external ear
0.625 0.375 0.000
H43.9 Disorder of vitreous body, unspecified
0.623 0.377 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.623 0.377 0.000
K11.9 Disease of salivary gland, unspecified
0.623 0.377 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.623 0.377 0.000
H35.0 Background retinopathy and retinal vascular changes
0.622 0.378 0.000
Q85.0 Neurofibromatosis (nonmalignant)
0.621 0.379 0.000
K11.5 Sialolithiasis
0.621 0.379 0.000
K86.2 Cyst of pancreas
0.621 0.379 0.000
K57.5 Diverticular disease of both small and large intestine without perforation or abscess
0.620 0.380 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.619 0.380 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.619 0.380 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.619 0.380 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.619 0.380 0.000
K80.3 Calculus of bile duct with cholangitis
0.618 0.382 0.000
S99 Other and unspecified injuries of ankle and foot
0.616 0.383 0.000
F60 Specific personality disorders
0.616 0.384 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.615 0.384 0.000
E88 Other metabolic disorders
0.614 0.386 0.000
V40-V49 Car occupant injured in transport accident
0.614 0.386 0.000
K86.3 Pseudocyst of pancreas
0.614 0.386 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.613 0.387 0.000
K82.9 Disease of gallbladder, unspecified
0.612 0.388 0.000
E20 Hypoparathyroidism
0.611 0.389 0.000
H02 Other disorders of eyelid
0.611 0.389 0.000
K57.0 Diverticular disease of small intestine with perforation and abscess
0.610 0.390 0.000
K13.2 Leukoplakia and other disturbances of oral epithelium, including tongue
0.610 0.390 0.000
K13.6 Irritative hyperplasia of oral mucosa
0.610 0.390 0.000
K13.5 Oral submucous fibrosis
0.610 0.390 0.000
K13.4 Granuloma and granuloma-like lesions of oral mucosa
0.610 0.390 0.000
K13.3 Hairy leukoplakia
0.610 0.390 0.000
K13.1 Cheek and lip biting
0.610 0.390 0.000
E24 Cushing's syndrome
0.609 0.391 0.000
H57.0 Anomalies of pupillary function
0.609 0.391 0.000
M20-M25 Other joint disorders
0.608 0.392 0.000
E34 Other endocrine disorders
0.607 0.393 0.000
S12 Fracture of neck
0.606 0.393 0.000
K08 Other disorders of teeth and supporting structures
0.606 0.394 0.000
K57.8 Diverticular disease of intestine, part unspecified, with perforation and abscess
0.605 0.395 0.000
K11.8 Other diseases of salivary glands
0.604 0.396 0.000
E85 Amyloidosis
0.603 0.397 0.000
E84 Cystic fibrosis
0.603 0.397 0.000
E79 Disorders of purine and pyrimidine metabolism
0.603 0.397 0.000
E77 Disorders of glycoprotein metabolism
0.603 0.397 0.000
E76 Disorders of glycosaminoglycan metabolism
0.603 0.397 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.603 0.397 0.000
E74 Other disorders of carbohydrate metabolism
0.603 0.397 0.000
E73 Lactose intolerance
0.603 0.397 0.000
E72 Other disorders of amino-acid metabolism
0.603 0.397 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.603 0.397 0.000
E70 Disorders of aromatic amino-acid metabolism
0.603 0.397 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.603 0.397 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.602 0.398 0.000
Y60 Unintentional cut, puncture, perforation or haemorrhage during surgical and medical care
0.602 0.398 0.000
H53-H54 Visual disturbances and blindness
0.602 0.398 0.000
E27 Other disorders of adrenal gland
0.601 0.399 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.600 0.400 0.000
M86-M90 Other osteopathies
0.600 0.400 0.000
K90-K93 Other diseases of the digestive system
0.600 0.400 0.000
V80-V89 Other land transport accidents
0.599 0.400 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.599 0.401 0.000
H61 Other disorders of external ear
0.599 0.401 0.000
H11.3 Conjunctival haemorrhage
0.598 0.401 0.000
F02.3 Dementia in Parkinson's disease
0.598 0.402 0.000
K82.4 Cholesterolosis of gallbladder
0.598 0.402 0.000
E83.9 Disorder of mineral metabolism, unspecified
0.597 0.403 0.000
E83.8 Other disorders of mineral metabolism
0.597 0.403 0.000
E83.2 Disorders of zinc metabolism
0.597 0.403 0.000
E83.0 Disorders of copper metabolism
0.597 0.403 0.000
S80-S89 Injuries to the knee and lower leg
0.597 0.403 0.000
Q87 Other specified congenital malformation syndromes affecting multiple systems
0.597 0.403 0.000
H43.8 Other disorders of vitreous body
0.597 0.403 0.000
H36 Retinal disorders in diseases classified elsewhere
0.596 0.403 0.000
K52.9 Non-infective gastro-enteritis and colitis, unspecified
0.596 0.404 0.000
K00.9 Disorder of tooth development, unspecified
0.596 0.404 0.000
S40-S49 Injuries to the shoulder and upper arm
0.596 0.404 0.000
Y35-Y36 Legal intervention and operations of war
0.594 0.406 0.000
Y10-Y34 Event of undetermined intent
0.594 0.406 0.000
Y00-Y09 Assault
0.594 0.406 0.000
X85-X99 Assault
0.594 0.406 0.000
X50-X57 Overexertion, travel and privation
0.594 0.406 0.000
X30-X39 Exposure to forces of nature
0.594 0.406 0.000
X10-X19 Contact with heat and hot substances
0.594 0.406 0.000
X00-X09 Exposure to smoke, fire and flames
0.594 0.406 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.594 0.406 0.000
W75-W84 Other accidental threats to breathing
0.594 0.406 0.000
W65-W74 Accidental drowning and submersion
0.594 0.406 0.000
W50-W64 Exposure to animate mechanical forces
0.594 0.406 0.000
V98-V99 Other and unspecified transport accidents
0.594 0.406 0.000
V95-V97 Air and space transport accidents
0.594 0.406 0.000
V90-V94 Water transport accidents
0.594 0.406 0.000
V70-V79 Bus occupant injured in transport accident
0.594 0.406 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.594 0.406 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.594 0.406 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.594 0.406 0.000
V01-V09 Pedestrian injured in transport accident
0.594 0.406 0.000
W00-W19 Falls
0.594 0.406 0.000
H13 Disorders of conjunctiva in diseases classified elsewhere
0.593 0.407 0.000
K06.2 Gingival and edentulous alveolar ridge lesions associated with trauma
0.592 0.408 0.000
Q89 Other congenital malformations, not elsewhere classified
0.591 0.409 0.000
S17 Crushing injury of neck
0.591 0.409 0.000
S15 Injury of blood vessels at neck level
0.591 0.409 0.000
S11 Open wound of neck
0.591 0.409 0.000
S18 Traumatic amputation at neck level
0.591 0.409 0.000
S16 Injury of muscle and tendon at neck level
0.591 0.409 0.000
S91.1 Open wound of toe(s) without damage to nail
0.590 0.410 0.000
E00-E07 Disorders of thyroid gland
0.587 0.413 0.000
K55.0 Acute vascular disorders of intestine
0.587 0.413 0.000
E50-E64 Other nutritional deficiencies
0.586 0.414 0.000
Q82 Other congenital malformations of skin
0.585 0.415 0.000
T78.2 Anaphylactic shock, unspecified
0.585 0.415 0.000
Q76 Congenital malformations of spine and bony thorax
0.585 0.415 0.000
X62 Intentional self-poisoning by and exposure to narcotics and psychodysleptics [hallucinogens], not elsewhere classified
0.585 0.415 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.585 0.415 0.000
E32 Diseases of thymus
0.585 0.415 0.000
E31 Polyglandular dysfunction
0.585 0.415 0.000
E30 Disorders of puberty, not elsewhere classified
0.585 0.415 0.000
E25 Adrenogenital disorders
0.585 0.415 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.584 0.416 0.000
H05 Disorders of orbit
0.583 0.417 0.000
T80.8 Other complications following infusion, transfusion and therapeutic injection
0.582 0.418 0.000
F23 Acute and transient psychotic disorders
0.582 0.418 0.000
S64.4 Injury of digital nerve of other finger
0.581 0.419 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.581 0.419 0.000
T75 Effects of other external causes
0.581 0.419 0.000
T74 Maltreatment syndromes
0.581 0.419 0.000
T73 Effects of other deprivation
0.581 0.419 0.000
T70 Effects of air pressure and water pressure
0.581 0.419 0.000
T69 Other effects of reduced temperature
0.581 0.419 0.000
T67 Effects of heat and light
0.581 0.419 0.000
T71 Asphyxiation
0.581 0.419 0.000
T66 Unspecified effects of radiation
0.581 0.419 0.000
F02.4 Dementia in human immunodeficiency virus [HIV] disease
0.581 0.419 0.000
F02.2 Dementia in Huntington's disease
0.581 0.419 0.000
F02.1 Dementia in Creutzfeldt-Jakob disease
0.581 0.419 0.000
F02.0 Dementia in Pick's disease
0.581 0.419 0.000
F01.8 Other vascular dementia
0.581 0.419 0.000
F01.3 Mixed cortical and subcortical vascular dementia
0.581 0.419 0.000
F01.2 Subcortical vascular dementia
0.581 0.419 0.000
F01.1 Multi-infarct dementia
0.581 0.419 0.000
F01.0 Vascular dementia of acute onset
0.581 0.419 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.580 0.420 0.000
U80.8 Agent resistant to other penicillin-related antibiotic
0.580 0.420 0.000
T68 Hypothermia
0.579 0.420 0.000
F53 Mental and behavioural disorders associated with the puerperium, not elsewhere classified
0.579 0.421 0.000
F51 Nonorganic sleep disorders
0.579 0.421 0.000
F59 Unspecified behavioural syndromes associated with physiological disturbances and physical factors
0.579 0.421 0.000
F55 Abuse of non-dependence-producing substances
0.579 0.421 0.000
F54 Psychological and behavioural factors associated with disorders or diseases classified elsewhere
0.579 0.421 0.000
E28 Ovarian dysfunction
0.577 0.423 0.000
K56.1 Intussusception
0.575 0.425 0.000
T87.4 Infection of amputation stump
0.575 0.425 0.000
Q86 Congenital malformation syndromes due to known exogenous causes, not elsewhere classified
0.574 0.426 0.000
Q84 Other congenital malformations of integument
0.574 0.426 0.000
Q83 Congenital malformations of breast
0.574 0.426 0.000
Q81 Epidermolysis bullosa
0.574 0.426 0.000
Q80 Congenital ichthyosis
0.574 0.426 0.000
Q12 Congenital lens malformations
0.574 0.426 0.000
K51.5 Mucosal proctocolitis
0.572 0.428 0.000
T88.8 Other specified complications of surgical and medical care, not elsewhere classified
0.572 0.428 0.000
S64.2 Injury of radial nerve at wrist and hand level
0.572 0.428 0.000
F52.2 Failure of genital response
0.571 0.429 0.000
U89 Agent resistant to other and unspecified antibiotics
0.571 0.429 0.000
K14.8 Other diseases of tongue
0.568 0.432 0.000
S10 Superficial injury of neck
0.568 0.432 0.000
M23 Internal derangement of knee
0.568 0.432 0.000
F22 Persistent delusional disorders
0.567 0.433 0.000
T83.4 Mechanical complication of other prosthetic devices, implants and grafts in genital tract
0.566 0.434 0.000
T20 Burn and corrosion of head and neck
0.566 0.434 0.000
K86.0 Alcohol-induced chronic pancreatitis
0.566 0.434 0.000
K52.8 Other specified non-infective gastro-enteritis and colitis
0.565 0.435 0.000
U84 Resistance to other antimicrobial drugs
0.561 0.439 0.000
U83 Resistance to other antibiotics
0.561 0.439 0.000
U82 Resistance to betalactam antibiotics
0.561 0.439 0.000
U85 Resistance to antineoplastic drugs
0.561 0.439 0.000
Y65 Other misadventures during surgical and medical care
0.561 0.439 0.000
T82.5 Mechanical complication of other cardiac and vascular devices and implants
0.561 0.439 0.000
S64.1 Injury of median nerve at wrist and hand level
0.561 0.439 0.000
Chapter I Certain infectious and parasitic diseases
0.560 0.440 0.000
H43.2 Crystalline deposits in vitreous body
0.560 0.440 0.000
H43.0 Vitreous prolapse
0.560 0.440 0.000
K65-K67 Diseases of peritoneum
0.560 0.440 0.000
T87.6 Other and unspecified complications of amputation stump
0.559 0.441 0.000
K11.7 Disturbances of salivary secretion
0.558 0.442 0.000
K11.4 Fistula of salivary gland
0.558 0.442 0.000
K11.3 Abscess of salivary gland
0.558 0.442 0.000
K11.1 Hypertrophy of salivary gland
0.558 0.442 0.000
K11.0 Atrophy of salivary gland
0.558 0.442 0.000
K55.1 Chronic vascular disorders of intestine
0.558 0.442 0.000
E46 Unspecified protein-energy malnutrition
0.558 0.442 0.000
K35-K38 Diseases of appendix
0.556 0.443 0.000
E23 Hypofunction and other disorders of pituitary gland
0.556 0.443 0.000
Q27 Other congenital malformations of peripheral vascular system
0.556 0.444 0.000
V10-V19 Pedal cyclist injured in transport accident
0.555 0.445 0.000
T36.0 Penicillins
0.553 0.447 0.000
M21 Other acquired deformities of limbs
0.553 0.447 0.000
H02.9 Disorder of eyelid, unspecified
0.553 0.447 0.000
T02 Fractures involving multiple body regions
0.552 0.448 0.000
K51.2 Ulcerative (chronic) proctitis
0.552 0.448 0.000
S80 Superficial injury of lower leg
0.552 0.448 0.000
H44.0 Purulent endophthalmitis
0.549 0.450 0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.547 0.452 0.000
F06.7 Mild cognitive disorder
0.547 0.453 0.000
H57.8 Other specified disorders of eye and adnexa
0.547 0.453 0.000
T40.9 Other and unspecified psychodysleptics [hallucinogens]
0.545 0.454 0.000
T40.8 Lysergide [LSD]
0.545 0.454 0.000
T40.7 Cannabis (derivatives)
0.545 0.454 0.000
T40.5 Cocaine
0.545 0.454 0.000
T40.3 Methadone
0.545 0.454 0.000
T40.1 Heroin
0.545 0.454 0.000
T40.0 Opium
0.545 0.454 0.000
Q17 Other congenital malformations of ear
0.545 0.454 0.000
Q16 Congenital malformations of ear causing impairment of hearing
0.545 0.454 0.000
Q15 Other congenital malformations of eye
0.545 0.454 0.000
Q14 Congenital malformations of posterior segment of eye
0.545 0.454 0.000
Q13 Congenital malformations of anterior segment of eye
0.545 0.454 0.000
Q11 Anophthalmos, microphthalmos and macrophthalmos
0.545 0.454 0.000
Q10 Congenital malformations of eyelid, lachrymal apparatus and orbit
0.545 0.454 0.000
K56.3 Gallstone ileus
0.545 0.454 0.000
Q21 Congenital malformations of cardiac septa
0.545 0.454 0.000
F68 Other disorders of adult personality and behaviour
0.545 0.455 0.000
F66 Psychological and behavioural disorders associated with sexual development and orientation
0.545 0.455 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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