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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs55736564
log Bayes Factor = 12.1044
Chromosome 19   position 55,180,067  (GRCh37) Explore rs55736564 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
I30-I52 Other forms of heart disease
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
Chapter VII Diseases of the eye and adnexa
1.000 0.000 0.000
I50 Heart failure
1.000 0.000 0.000
E10-E14 Diabetes mellitus
0.999 0.001 0.000
E10 Insulin-dependent diabetes mellitus
0.998 0.002 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.997 0.003 0.000
H40-H42 Glaucoma
0.996 0.004 0.000
H40 Glaucoma
0.994 0.006 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.989 0.011 0.000
Chapter X Diseases of the respiratory system
0.987 0.013 0.000
E10.9 Without complications
0.986 0.014 0.000
H30-H36 Disorders of choroid and retina
0.984 0.016 0.000
I50.9 Heart failure, unspecified
0.980 0.020 0.000
I50.0 Congestive heart failure
0.977 0.023 0.000
S00-S09 Injuries to the head
0.976 0.024 0.000
E70-E90 Metabolic disorders
0.975 0.025 0.000
H40.9 Glaucoma, unspecified
0.973 0.027 0.000
Chapter V Mental and behavioural disorders
0.973 0.027 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.968 0.032 0.000
I34 Nonrheumatic mitral valve disorders
0.962 0.038 0.000
I50.1 Left ventricular failure
0.957 0.043 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.956 0.044 0.000
H36 Retinal disorders in diseases classified elsewhere
0.944 0.056 0.000
E80.4 Gilbert's syndrome
0.942 0.058 0.000
I47 Paroxysmal tachycardia
0.939 0.061 0.000
J84 Other interstitial pulmonary diseases
0.939 0.061 0.000
S06 Intracranial injury
0.938 0.062 0.000
E11 Non-insulin-dependent diabetes mellitus
0.938 0.062 0.000
Chapter VIII Diseases of the ear and mastoid process
0.935 0.065 0.000
I71 Aortic aneurysm and dissection
0.931 0.069 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.920 0.080 0.000
H36.0 Diabetic retinopathy
0.915 0.085 0.000
H40.0 Glaucoma suspect
0.907 0.093 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.897 0.103 0.000
J84.1 Other interstitial pulmonary diseases with fibrosis
0.897 0.103 0.000
S02 Fracture of skull and facial bones
0.897 0.103 0.000
H34 Retinal vascular occlusions
0.893 0.107 0.000
I51 Complications and ill-defined descriptions of heart disease
0.893 0.107 0.000
I34.0 Mitral (valve) insufficiency
0.892 0.108 0.000
H35 Other retinal disorders
0.891 0.109 0.000
H40.2 Primary angle-closure glaucoma
0.889 0.111 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.888 0.112 0.000
I05-I09 Chronic rheumatic heart diseases
0.887 0.113 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.885 0.115 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.881 0.119 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.880 0.120 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.880 0.120 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.879 0.121 0.000
J40-J47 Chronic lower respiratory diseases
0.878 0.122 0.000
E10.3 With ophthalmic complications
0.874 0.126 0.000
Chapter VI Diseases of the nervous system
0.873 0.127 0.000
I47.2 Ventricular tachycardia
0.870 0.130 0.000
H53-H54 Visual disturbances and blindness
0.868 0.132 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.866 0.134 0.000
E11.2 With renal complications
0.865 0.135 0.000
E65-E68 Obesity and other hyperalimentation
0.862 0.138 0.000
I72 Other aneurysm
0.861 0.139 0.000
F30-F39 Mood [affective] disorders
0.861 0.139 0.000
I34.1 Mitral (valve) prolapse
0.855 0.145 0.000
H65-H75 Diseases of middle ear and mastoid
0.855 0.145 0.000
E11.5 With peripheral circulatory complications
0.855 0.145 0.000
J60-J70 Lung diseases due to external agents
0.852 0.148 0.000
E10.1 With ketoacidosis
0.849 0.151 0.000
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.849 0.151 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.845 0.155 0.000
E10.4 With neurological complications
0.842 0.158 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.842 0.158 0.000
J45 Asthma
0.841 0.159 0.000
S90-S99 Injuries to the ankle and foot
0.837 0.163 0.000
T42.4 Benzodiazepines
0.835 0.165 0.000
G40-G47 Episodic and paroxysmal disorders
0.831 0.169 0.000
J09-J18 Influenza and pneumonia
0.830 0.170 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.829 0.171 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.826 0.174 0.000
S06.5 Traumatic subdural haemorrhage
0.823 0.177 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.822 0.178 0.000
I42 Cardiomyopathy
0.818 0.182 0.000
H40.8 Other glaucoma
0.814 0.186 0.000
J84.9 Interstitial pulmonary disease, unspecified
0.809 0.191 0.000
I08 Multiple valve diseases
0.809 0.191 0.000
H35.3 Degeneration of macula and posterior pole
0.807 0.193 0.000
S02.0 Fracture of vault of skull
0.805 0.195 0.000
J45.9 Asthma, unspecified
0.803 0.197 0.000
I74 Arterial embolism and thrombosis
0.803 0.197 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.802 0.198 0.000
J90-J94 Other diseases of pleura
0.802 0.198 0.000
J80 Adult respiratory distress syndrome
0.802 0.198 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.801 0.199 0.000
H60-H62 Diseases of external ear
0.800 0.200 0.000
T90 Sequelae of injuries of head
0.797 0.203 0.000
T45.0 Antiallergic and antiemetic drugs
0.797 0.203 0.000
F10.1 Harmful use
0.797 0.203 0.000
I71.0 Dissection of aorta [any part]
0.793 0.207 0.000
S40-S49 Injuries to the shoulder and upper arm
0.791 0.209 0.000
H18 Other disorders of cornea
0.791 0.209 0.000
S06.3 Focal brain injury
0.791 0.209 0.000
H34.8 Other retinal vascular occlusions
0.789 0.211 0.000
I47.1 Supraventricular tachycardia
0.788 0.212 0.000
E78.5 Hyperlipidaemia, unspecified
0.786 0.214 0.000
I33 Acute and subacute endocarditis
0.786 0.214 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.784 0.216 0.000
I77 Other disorders of arteries and arterioles
0.784 0.216 0.000
H80-H83 Diseases of inner ear
0.780 0.220 0.000
I78 Diseases of capillaries
0.776 0.224 0.000
S10-S19 Injuries to the neck
0.775 0.225 0.000
F80-F89 Disorders of psychological development
0.775 0.225 0.000
H10-H13 Disorders of conjunctiva
0.773 0.227 0.000
T51 Toxic effect of alcohol
0.770 0.230 0.000
J43 Emphysema
0.770 0.230 0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.767 0.233 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.766 0.234 0.000
S06.2 Diffuse brain injury
0.764 0.236 0.000
I51.8 Other ill-defined heart diseases
0.764 0.236 0.000
G44 Other headache syndromes
0.764 0.236 0.000
H66 Suppurative and unspecified otitis media
0.763 0.237 0.000
T79-T79 Certain early complications of trauma
0.763 0.237 0.000
I71.9 Aortic aneurysm of unspecified site, without mention of rupture
0.763 0.237 0.000
S02.1 Fracture of base of skull
0.760 0.240 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.759 0.241 0.000
F33 Recurrent depressive disorder
0.759 0.241 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.757 0.243 0.000
F99-F99 Unspecified mental disorder
0.757 0.243 0.000
J81 Pulmonary oedema
0.756 0.244 0.000
H53 Visual disturbances
0.756 0.244 0.000
I46 Cardiac arrest
0.754 0.246 0.000
E11.3 With ophthalmic complications
0.754 0.246 0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.753 0.247 0.000
E66 Obesity
0.752 0.248 0.000
I30 Acute pericarditis
0.751 0.249 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.747 0.253 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.747 0.253 0.000
S01 Open wound of head
0.743 0.257 0.000
E10.5 With peripheral circulatory complications
0.742 0.257 0.000
I72.4 Aneurysm of artery of lower extremity
0.742 0.258 0.000
H73 Other disorders of tympanic membrane
0.741 0.259 0.000
S06.50 Traumatic subdural haemorrhage (without open intracranial wound)
0.741 0.259 0.000
I60-I69 Cerebrovascular diseases
0.740 0.260 0.000
H40.1 Primary open-angle glaucoma
0.740 0.260 0.000
S02.00 Fracture of vault of skull (closed)
0.739 0.261 0.000
E14 Unspecified diabetes mellitus
0.738 0.262 0.000
F60-F69 Disorders of adult personality and behaviour
0.738 0.262 0.000
I38 Endocarditis, valve unspecified
0.737 0.263 0.000
H34.2 Other retinal artery occlusions
0.735 0.264 0.000
S80-S89 Injuries to the knee and lower leg
0.734 0.266 0.000
E13 Other specified diabetes mellitus
0.734 0.266 0.000
S06.6 Traumatic subarachnoid haemorrhage
0.732 0.268 0.000
T39.1 4-Aminophenol derivatives
0.730 0.270 0.000
Chapter I Certain infectious and parasitic diseases
0.730 0.270 0.000
J18 Pneumonia, organism unspecified
0.730 0.270 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.727 0.273 0.000
E66.8 Other obesity
0.725 0.275 0.000
S92 Fracture of foot, except ankle
0.724 0.276 0.000
J69 Pneumonitis due to solids and liquids
0.724 0.276 0.000
Q50-Q56 Congenital malformations of genital organs
0.722 0.278 0.000
G45 Transient cerebral ischaemic attacks and related syndromes
0.721 0.279 0.000
S70-S79 Injuries to the hip and thigh
0.721 0.279 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.719 0.281 0.000
I73 Other peripheral vascular diseases
0.718 0.282 0.000
H43-H45 Disorders of vitreous body and globe
0.718 0.282 0.000
T43.5 Other and unspecified antipsychotics and neuroleptics
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
I52 Other heart disorders in diseases classified elsewhere
0.717 0.283 0.000
I48 Atrial fibrillation and flutter
0.717 0.283 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.717 0.283 0.000
I41 Myocarditis in diseases classified elsewhere
0.717 0.283 0.000
I40 Acute myocarditis
0.717 0.283 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.717 0.283 0.000
I37 Pulmonary valve disorders
0.717 0.283 0.000
I36 Nonrheumatic tricuspid valve disorders
0.717 0.283 0.000
I32 Pericarditis in diseases classified elsewhere
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
E12 Malnutrition-related diabetes mellitus
0.717 0.283 0.000
E11.1 With ketoacidosis
0.716 0.284 0.000
E10.8 With unspecified complications
0.715 0.285 0.000
E10.7 With multiple complications
0.715 0.285 0.000
E10.6 With other specified complications
0.715 0.285 0.000
E10.2 With renal complications
0.715 0.285 0.000
E10.0 With coma
0.715 0.285 0.000
S06.4 Epidural haemorrhage
0.715 0.285 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.715 0.285 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.715 0.285 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.715 0.285 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.715 0.285 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.715 0.285 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.715 0.285 0.000
T36 Poisoning by systemic antibiotics
0.715 0.285 0.000
H42 Glaucoma in diseases classified elsewhere
0.714 0.285 0.000
E40-E46 Malnutrition
0.713 0.286 0.000
T43.0 Tricyclic and tetracyclic antidepressants
0.713 0.287 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.713 0.287 0.000
H60 Otitis externa
0.713 0.287 0.000
H40.6 Glaucoma secondary to drugs
0.713 0.287 0.000
H40.4 Glaucoma secondary to eye inflammation
0.713 0.287 0.000
H40.3 Glaucoma secondary to eye trauma
0.713 0.287 0.000
T51.0 Ethanol
0.712 0.288 0.000
T43.3 Phenothiazine antipsychotics and neuroleptics
0.710 0.290 0.000
H72 Perforation of tympanic membrane
0.710 0.290 0.000
F10.2 Dependence syndrome
0.709 0.291 0.000
J00-J06 Acute upper respiratory infections
0.708 0.292 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.705 0.295 0.000
H31 Other disorders of choroid
0.705 0.295 0.000
H30 Chorioretinal inflammation
0.705 0.295 0.000
T50.9 Other and unspecified drugs, medicaments and biological substances
0.704 0.296 0.000
G20-G26 Extrapyramidal and movement disorders
0.703 0.297 0.000
S02.9 Fracture of skull and facial bones, part unspecified
0.703 0.297 0.000
S50-S59 Injuries to the elbow and forearm
0.702 0.298 0.000
H53.1 Subjective visual disturbances
0.700 0.300 0.000
S08 Traumatic amputation of part of head
0.700 0.300 0.000
S07 Crushing injury of head
0.700 0.300 0.000
S05 Injury of eye and orbit
0.700 0.300 0.000
S04 Injury of cranial nerves
0.700 0.300 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.700 0.300 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.700 0.300 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.699 0.301 0.000
E85 Amyloidosis
0.699 0.301 0.000
E84 Cystic fibrosis
0.699 0.301 0.000
E79 Disorders of purine and pyrimidine metabolism
0.699 0.301 0.000
E77 Disorders of glycoprotein metabolism
0.699 0.301 0.000
E76 Disorders of glycosaminoglycan metabolism
0.699 0.301 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.699 0.301 0.000
E74 Other disorders of carbohydrate metabolism
0.699 0.301 0.000
E73 Lactose intolerance
0.699 0.301 0.000
E72 Other disorders of amino-acid metabolism
0.699 0.301 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.699 0.301 0.000
E70 Disorders of aromatic amino-acid metabolism
0.699 0.301 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.699 0.301 0.000
J18.0 Bronchopneumonia, unspecified
0.698 0.302 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.697 0.303 0.000
F70-F79 Mental retardation
0.697 0.303 0.000
I08.1 Disorders of both mitral and tricuspid valves
0.697 0.303 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.695 0.305 0.000
J82 Pulmonary eosinophilia, not elsewhere classified
0.694 0.306 0.000
I05 Rheumatic mitral valve diseases
0.694 0.306 0.000
I51.6 Cardiovascular disease, unspecified
0.692 0.308 0.000
J46 Status asthmaticus
0.692 0.308 0.000
H66.9 Otitis media, unspecified
0.691 0.309 0.000
E50-E64 Other nutritional deficiencies
0.691 0.309 0.000
F10.9 Unspecified mental and behavioural disorder
0.691 0.309 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.690 0.310 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.690 0.310 0.000
I34.9 Nonrheumatic mitral valve disorder, unspecified
0.690 0.310 0.000
I34.8 Other nonrheumatic mitral valve disorders
0.690 0.310 0.000
I34.2 Nonrheumatic mitral (valve) stenosis
0.690 0.310 0.000
I08.3 Combined disorders of mitral, aortic and tricuspid valves
0.689 0.311 0.000
H04 Disorders of lachrymal system
0.686 0.314 0.000
E87.5 Hyperkalaemia
0.685 0.315 0.000
E80.7 Disorder of bilirubin metabolism, unspecified
0.685 0.315 0.000
E80.6 Other disorders of bilirubin metabolism
0.685 0.315 0.000
E80.5 Crigler-Najjar syndrome
0.685 0.315 0.000
E80.3 Defects of catalase and peroxydase
0.685 0.315 0.000
E80.2 Other porphyria
0.685 0.315 0.000
E80.1 Porphyria cutanea tarda
0.685 0.315 0.000
E80.0 Hereditary erythropoietic porphyria
0.685 0.315 0.000
S06.30 Focal brain injury (without open intracranial wound)
0.685 0.315 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.684 0.315 0.000
T39.0 Salicylates
0.684 0.316 0.000
T90.2 Sequelae of fracture of skull and facial bones
0.683 0.317 0.000
Q80-Q89 Other congenital malformations
0.683 0.317 0.000
I99 Other and unspecified disorders of circulatory system
0.682 0.318 0.000
E78.2 Mixed hyperlipidaemia
0.682 0.318 0.000
S00 Superficial injury of head
0.682 0.318 0.000
I51.9 Heart disease, unspecified
0.682 0.318 0.000
S01.0 Open wound of scalp
0.680 0.320 0.000
H16 Keratitis
0.679 0.321 0.000
S02.8 Fractures of other skull and facial bones
0.678 0.321 0.000
S32 Fracture of lumbar spine and pelvis
0.678 0.322 0.000
Chapter XXII Codes for special purposes
0.677 0.323 0.000
H36.8 Other retinal disorders in diseases classified elsewhere
0.677 0.323 0.000
J93 Pneumothorax
0.676 0.324 0.000
F11 Mental and behavioural disorders due to use of opioids
0.675 0.325 0.000
J45.0 Predominantly allergic asthma
0.674 0.326 0.000
I47.0 Reentry ventricular arrhythmia
0.673 0.327 0.000
J84.8 Other specified interstitial pulmonary diseases
0.673 0.327 0.000
J84.0 Alveolar and parietoalveolar conditions
0.673 0.327 0.000
T91 Sequelae of injuries of neck and trunk
0.673 0.327 0.000
A00-A09 Intestinal infectious diseases
0.673 0.327 0.000
I72.8 Aneurysm of other specified arteries
0.673 0.327 0.000
S06.9 Intracranial injury, unspecified
0.673 0.327 0.000
S06.8 Other intracranial injuries
0.673 0.327 0.000
S06.7 Intracranial injury with prolonged coma
0.673 0.327 0.000
S06.1 Traumatic cerebral oedema
0.673 0.327 0.000
S06.0 Concussion
0.673 0.327 0.000
E11.8 With unspecified complications
0.672 0.328 0.000
E11.7 With multiple complications
0.672 0.328 0.000
E11.6 With other specified complications
0.672 0.328 0.000
E11.0 With coma
0.672 0.328 0.000
I60 Subarachnoid haemorrhage
0.672 0.328 0.000
E88 Other metabolic disorders
0.671 0.329 0.000
E78.9 Disorder of lipoprotein metabolism, unspecified
0.670 0.330 0.000
Chapter XX External causes of morbidity and mortality
0.670 0.330 0.000
J61 Pneumoconiosis due to asbestos and other mineral fibres
0.669 0.331 0.000
G44.2 Tension-type headache
0.668 0.332 0.000
T90.9 Sequelae of unspecified injury of head
0.668 0.332 0.000
I51.7 Cardiomegaly
0.668 0.332 0.000
F12 Mental and behavioural disorders due to use of cannabinoids
0.668 0.332 0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.668 0.332 0.000
I77.9 Disorder of arteries and arterioles, unspecified
0.668 0.332 0.000
I49 Other cardiac arrhythmias
0.667 0.332 0.000
I71.8 Aortic aneurysm of unspecified site, ruptured
0.667 0.333 0.000
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture
0.667 0.333 0.000
I71.5 Thoracoabdominal aortic aneurysm, ruptured
0.667 0.333 0.000
I71.3 Abdominal aortic aneurysm, ruptured
0.667 0.333 0.000
I71.1 Thoracic aortic aneurysm, ruptured
0.667 0.333 0.000
H18.6 Keratoconus
0.667 0.333 0.000
I79.2 Peripheral angiopathy in diseases classified elsewhere
0.665 0.334 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.663 0.337 0.000
H54 Blindness and low vision
0.663 0.337 0.000
S02.10 Fracture of base of skull (closed)
0.663 0.337 0.000
H35.5 Hereditary retinal dystrophy
0.661 0.339 0.000
E16 Other disorders of pancreatic internal secretion
0.661 0.339 0.000
F10.0 Acute intoxication
0.661 0.339 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.660 0.340 0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants
0.660 0.340 0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified
0.660 0.340 0.000
T42.5 Mixed antiepileptics, not elsewhere classified
0.660 0.340 0.000
T42.3 Barbiturates
0.660 0.340 0.000
T42.2 Succinimides and oxazolidinediones
0.660 0.340 0.000
T42.1 Iminostilbenes
0.660 0.340 0.000
T42.0 Hydantoin derivatives
0.660 0.340 0.000
H35.8 Other specified retinal disorders
0.659 0.340 0.000
H35.0 Background retinopathy and retinal vascular changes
0.659 0.341 0.000
H73.8 Other specified disorders of tympanic membrane
0.659 0.341 0.000
I70 Atherosclerosis
0.658 0.341 0.000
H40.5 Glaucoma secondary to other eye disorders
0.658 0.342 0.000
J94 Other pleural conditions
0.658 0.342 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.657 0.343 0.000
F31 Bipolar affective disorder
0.657 0.343 0.000
G70-G73 Diseases of myoneural junction and muscle
0.656 0.344 0.000
J43.2 Centrilobular emphysema
0.655 0.345 0.000
J15 Bacterial pneumonia, not elsewhere classified
0.652 0.348 0.000
H60.9 Otitis externa, unspecified
0.651 0.349 0.000
I42.1 Obstructive hypertrophic cardiomyopathy
0.650 0.350 0.000
Q60-Q64 Congenital malformations of the urinary system
0.648 0.352 0.000
I08.2 Disorders of both aortic and tricuspid valves
0.647 0.353 0.000
T93 Sequelae of injuries of lower limb
0.647 0.353 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.647 0.353 0.000
I44 Atrioventricular and left bundle-branch block
0.646 0.354 0.000
I42.9 Cardiomyopathy, unspecified
0.645 0.354 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.643 0.357 0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified
0.643 0.357 0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified
0.643 0.357 0.000
T39.4 Antirheumatics, not elsewhere classified
0.643 0.357 0.000
T39.2 Pyrazolone derivatives
0.643 0.357 0.000
S02.7 Multiple fractures involving skull and facial bones
0.643 0.357 0.000
S02.5 Fracture of tooth
0.643 0.357 0.000
S02.3 Fracture of orbital floor
0.643 0.357 0.000
J95-J99 Other diseases of the respiratory system
0.643 0.357 0.000
I47.9 Paroxysmal tachycardia, unspecified
0.642 0.358 0.000
E65 Localised adiposity
0.640 0.359 0.000
H34.9 Retinal vascular occlusion, unspecified
0.640 0.360 0.000
H34.1 Central retinal artery occlusion
0.640 0.360 0.000
H34.0 Transient retinal artery occlusion
0.640 0.360 0.000
I51.5 Myocardial degeneration
0.640 0.360 0.000
I51.4 Myocarditis, unspecified
0.640 0.360 0.000
I51.3 Intracardiac thrombosis, not elsewhere classified
0.640 0.360 0.000
I51.2 Rupture of papillary muscle, not elsewhere classified
0.640 0.360 0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.640 0.360 0.000
I51.0 Cardiac septal defect, acquired
0.640 0.360 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.639 0.361 0.000
S06.20 Diffuse brain injury (without open intracranial wound)
0.639 0.361 0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.639 0.361 0.000
H35.7 Separation of retinal layers
0.639 0.361 0.000
H35.6 Retinal haemorrhage
0.639 0.361 0.000
H35.4 Peripheral retinal degeneration
0.639 0.361 0.000
H35.2 Other proliferative retinopathy
0.639 0.361 0.000
H35.1 Retinopathy of prematurity
0.639 0.361 0.000
H21 Other disorders of iris and ciliary body
0.637 0.363 0.000
T98 Sequelae of other and unspecified effects of external causes
0.637 0.363 0.000
T95 Sequelae of burns, corrosions and frostbite
0.637 0.363 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.637 0.363 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.637 0.363 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.637 0.363 0.000
S42 Fracture of shoulder and upper arm
0.637 0.363 0.000
I09 Other rheumatic heart diseases
0.636 0.364 0.000
I06 Rheumatic aortic valve diseases
0.636 0.364 0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances
0.635 0.365 0.000
F18 Mental and behavioural disorders due to use of volatile solvents
0.635 0.365 0.000
F16 Mental and behavioural disorders due to use of hallucinogens
0.635 0.365 0.000
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine
0.635 0.365 0.000
F14 Mental and behavioural disorders due to use of cocaine
0.635 0.365 0.000
F13 Mental and behavioural disorders due to use of sedatives or hypnotics
0.635 0.365 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.635 0.365 0.000
J14 Pneumonia due to Haemophilus influenzae
0.634 0.366 0.000
H72.9 Perforation of tympanic membrane, unspecified
0.633 0.367 0.000
F32 Depressive episode
0.632 0.368 0.000
E11.4 With neurological complications
0.632 0.368 0.000
J69.0 Pneumonitis due to food and vomit
0.632 0.368 0.000
I33.0 Acute and subacute infective endocarditis
0.632 0.368 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.631 0.368 0.000
Q35-Q37 Cleft lip and cleft palate
0.631 0.368 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.631 0.368 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.631 0.368 0.000
Q00-Q07 Congenital malformations of the nervous system
0.631 0.368 0.000
H81 Disorders of vestibular function
0.631 0.369 0.000
T43.9 Psychotropic drug, unspecified
0.631 0.369 0.000
T43.8 Other psychotropic drugs, not elsewhere classified
0.631 0.369 0.000
T43.6 Psychostimulants with abuse potential
0.631 0.369 0.000
T43.4 Butyrophenone and thioxanthene neuroleptics
0.631 0.369 0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants
0.631 0.369 0.000
T45.9 Primarily systemic and haematological agent, unspecified
0.631 0.369 0.000
T45.8 Other primarily systemic and haematological agents
0.631 0.369 0.000
T45.7 Anticoagulant antagonists, vitamin K and other coagulants
0.631 0.369 0.000
T45.6 Fibrinolysis-affecting drugs
0.631 0.369 0.000
T45.5 Anticoagulants
0.631 0.369 0.000
T45.4 Iron and its compounds
0.631 0.369 0.000
T45.3 Enzymes, not elsewhere classified
0.631 0.369 0.000
T45.2 Vitamins, not elsewhere classified
0.631 0.369 0.000
T45.1 Antineoplastic and immunosuppressive drugs
0.631 0.369 0.000
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs
0.631 0.369 0.000
G47 Sleep disorders
0.631 0.369 0.000
H35.9 Retinal disorder, unspecified
0.630 0.369 0.000
H22 Disorders of iris and ciliary body in diseases classified elsewhere
0.630 0.370 0.000
H19 Disorders of sclera and cornea in diseases classified elsewhere
0.630 0.370 0.000
H17 Corneal scars and opacities
0.630 0.370 0.000
H15 Disorders of sclera
0.630 0.370 0.000
S41 Open wound of shoulder and upper arm
0.630 0.370 0.000
J41 Simple and mucopurulent chronic bronchitis
0.629 0.371 0.000
G35 Multiple sclerosis
0.629 0.371 0.000
I42.8 Other cardiomyopathies
0.629 0.371 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.627 0.372 0.000
H83 Other diseases of inner ear
0.627 0.373 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.627 0.373 0.000
G40 Epilepsy
0.627 0.373 0.000
H18.4 Corneal degeneration
0.626 0.374 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.626 0.374 0.000
H55-H59 Other disorders of eye and adnexa
0.625 0.375 0.000
J92 Pleural plaque
0.625 0.375 0.000
I78.1 Naevus, nonneoplastic
0.624 0.376 0.000
I10-I15 Hypertensive diseases
0.623 0.377 0.000
S92.0 Fracture of calcaneus
0.622 0.377 0.000
J43.9 Emphysema, unspecified
0.622 0.378 0.000
S80 Superficial injury of lower leg
0.622 0.378 0.000
H53.4 Visual field defects
0.622 0.378 0.000
T65 Toxic effect of other and unspecified substances
0.621 0.379 0.000
T63 Toxic effect of contact with venomous animals
0.621 0.379 0.000
T62 Toxic effect of other noxious substances eaten as food
0.621 0.379 0.000
T61 Toxic effect of noxious substances eaten as seafood
0.621 0.379 0.000
T60 Toxic effect of pesticides
0.621 0.379 0.000
T59 Toxic effect of other gases, fumes and vapours
0.621 0.379 0.000
T57 Toxic effect of other inorganic substances
0.621 0.379 0.000
T56 Toxic effect of metals
0.621 0.379 0.000
T54 Toxic effect of corrosive substances
0.621 0.379 0.000
T53 Toxic effect of halogen derivatives of aliphatic and aromatic hydrocarbone
0.621 0.379 0.000
T52 Toxic effect of organic solvents
0.621 0.379 0.000
T64 Toxic effect of aflatoxin and other mycotoxin food contaminants
0.621 0.379 0.000
T58 Toxic effect of carbon monoxide
0.621 0.379 0.000
T55 Toxic effect of soaps and detergents
0.621 0.379 0.000
A04 Other bacterial intestinal infections
0.618 0.382 0.000
T92 Sequelae of injuries of upper limb
0.618 0.382 0.000
E67 Other hyperalimentation
0.618 0.382 0.000
E68 Sequelae of hyperalimentation
0.618 0.382 0.000
I72.9 Aneurysm of unspecified site
0.617 0.383 0.000
I72.6 Aneurysm and dissection of vertebral artery
0.617 0.383 0.000
I72.5 Aneurysm and dissection of other precerebral arteries
0.617 0.383 0.000
I72.3 Aneurysm of iliac artery
0.617 0.383 0.000
I72.2 Aneurysm of renal artery
0.617 0.383 0.000
I72.1 Aneurysm of artery of upper extremity
0.617 0.383 0.000
I72.0 Aneurysm of carotid artery
0.617 0.383 0.000
F38 Other mood [affective] disorders
0.617 0.383 0.000
F34 Persistent mood [affective] disorders
0.617 0.383 0.000
F30 Manic episode
0.617 0.383 0.000
F39 Unspecified mood [affective] disorder
0.617 0.383 0.000
J11 Influenza, virus not identified
0.616 0.384 0.000
I95 Hypotension
0.616 0.384 0.000
G44.8 Other specified headache syndromes
0.615 0.385 0.000
H74 Other disorders of middle ear and mastoid
0.615 0.385 0.000
I60.9 Subarachnoid haemorrhage, unspecified
0.615 0.385 0.000
H18.8 Other specified disorders of cornea
0.614 0.385 0.000
E14.3 With ophthalmic complications
0.614 0.386 0.000
I69 Sequelae of cerebrovascular disease
0.614 0.386 0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere
0.613 0.387 0.000
H70 Mastoiditis and related conditions
0.613 0.387 0.000
H69 Other disorders of Eustachian tube
0.613 0.387 0.000
H68 Eustachian salpingitis and obstruction
0.613 0.387 0.000
H67 Otitis media in diseases classified elsewhere
0.613 0.387 0.000
F33.9 Recurrent depressive disorder, unspecified
0.612 0.388 0.000
J70 Respiratory conditions due to other external agents
0.610 0.389 0.000
J68 Respiratory conditions due to inhalation of chemicals, gases, fumes and vapours
0.610 0.389 0.000
J67 Hypersensitivity pneumonitis due to organic dust
0.610 0.389 0.000
J66 Airway disease due to specific organic dust
0.610 0.389 0.000
J63 Pneumoconiosis due to other inorganic dusts
0.610 0.389 0.000
J62 Pneumoconiosis due to dust containing silica
0.610 0.389 0.000
J65 Pneumoconiosis associated with tuberculosis
0.610 0.389 0.000
J64 Unspecified pneumoconiosis
0.610 0.389 0.000
J60 Coalworker's pneumoconiosis
0.610 0.389 0.000
I45 Other conduction disorders
0.610 0.390 0.000
S01.2 Open wound of nose
0.609 0.390 0.000
B35-B49 Mycoses
0.609 0.391 0.000
F81 Specific developmental disorders of scholastic skills
0.608 0.391 0.000
I49.1 Atrial premature depolarisation
0.608 0.392 0.000
I42.2 Other hypertrophic cardiomyopathy
0.606 0.394 0.000
G45.9 Transient cerebral ischaemic attack, unspecified
0.606 0.394 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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