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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs55754459
log Bayes Factor = 43.0914
Chromosome 6   position 161,551,176  (GRCh37) Explore rs55754459 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E78.0 Pure hypercholesterolaemia
1.000 0.000 0.000
I25.1 Atherosclerotic heart disease
1.000 0.000 0.000
Z82.4 Family history of ischaemic heart disease and other diseases of the circulatory system
1.000 0.000 0.000
I25 Chronic ischaemic heart disease
1.000 0.000 0.000
I20 Angina pectoris
1.000 0.000 0.000
I20-I25 Ischaemic heart diseases
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
1.000 0.000 0.000
Z95 Presence of cardiac and vascular implants and grafts
1.000 0.000 0.000
E70-E90 Metabolic disorders
1.000 0.000 0.000
I20.9 Angina pectoris, unspecified
1.000 0.000 0.000
I25.2 Old myocardial infarction
1.000 0.000 0.000
I25.9 Chronic ischaemic heart disease, unspecified
1.000 0.000 0.000
I30-I52 Other forms of heart disease
1.000 0.000 0.000
Z82 Family history of certain disabilities and chronic diseases leading to disablement
1.000 0.000 0.000
Z95.1 Presence of aortocoronary bypass graft
0.999 0.001 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.999 0.001 0.000
Chapter XXI Factors influencing health status and contact with health services
0.999 0.001 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.999 0.001 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.999 0.001 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.996 0.004 0.000
I20.0 Unstable angina
0.995 0.005 0.000
Z95.5 Presence of coronary angioplasty implant and graft
0.992 0.008 0.000
E87.1 Hypo-osmolality and hyponatraemia
0.989 0.011 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.989 0.011 0.000
I21 Acute myocardial infarction
0.989 0.011 0.000
I50 Heart failure
0.979 0.021 0.000
Chapter X Diseases of the respiratory system
0.977 0.023 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.977 0.023 0.000
I35 Nonrheumatic aortic valve disorders
0.973 0.027 0.000
I10-I15 Hypertensive diseases
0.970 0.030 0.000
I24 Other acute ischaemic heart diseases
0.970 0.030 0.000
I77 Other disorders of arteries and arterioles
0.969 0.031 0.000
Chapter VI Diseases of the nervous system
0.969 0.031 0.000
Chapter VIII Diseases of the ear and mastoid process
0.961 0.039 0.000
I51 Complications and ill-defined descriptions of heart disease
0.961 0.039 0.000
E78.5 Hyperlipidaemia, unspecified
0.954 0.046 0.000
J09-J18 Influenza and pneumonia
0.950 0.050 0.000
Z71 Persons encountering health services for other counselling and medical advice, not elsewhere classified
0.944 0.056 0.000
G40-G47 Episodic and paroxysmal disorders
0.941 0.059 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.934 0.066 0.000
I50.1 Left ventricular failure
0.931 0.069 0.000
Chapter VII Diseases of the eye and adnexa
0.930 0.070 0.000
I10 Essential (primary) hypertension
0.929 0.071 0.000
Chapter I Certain infectious and parasitic diseases
0.927 0.073 0.000
I20.8 Other forms of angina pectoris
0.924 0.076 0.000
G43 Migraine
0.923 0.077 0.000
J18 Pneumonia, organism unspecified
0.922 0.078 0.000
I35.0 Aortic (valve) stenosis
0.920 0.080 0.000
M45-M49 Spondylopathies
0.919 0.081 0.000
I21.4 Acute subendocardial myocardial infarction
0.915 0.085 0.000
I24.8 Other forms of acute ischaemic heart disease
0.913 0.087 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.911 0.089 0.000
J18.1 Lobar pneumonia, unspecified
0.910 0.090 0.000
M47 Spondylosis
0.909 0.091 0.000
M47.9 Spondylosis, unspecified
0.904 0.096 0.000
I71 Aortic aneurysm and dissection
0.901 0.099 0.000
H25-H28 Disorders of lens
0.900 0.100 0.000
G43.9 Migraine, unspecified
0.899 0.101 0.000
I21.1 Acute transmural myocardial infarction of inferior wall
0.897 0.103 0.000
I46 Cardiac arrest
0.896 0.104 0.000
I77.9 Disorder of arteries and arterioles, unspecified
0.896 0.104 0.000
E87.7 Fluid overload
0.896 0.104 0.000
M47.96 Spondylosis, unspecified (Lumbar region)
0.894 0.106 0.000
I60-I69 Cerebrovascular diseases
0.892 0.108 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.892 0.108 0.000
I24.9 Acute ischaemic heart disease, unspecified
0.890 0.110 0.000
Z95.0 Presence of cardiac pacemaker
0.889 0.111 0.000
H25 Senile cataract
0.887 0.113 0.000
Z71.8 Other specified counselling
0.886 0.114 0.000
H25.8 Other senile cataract
0.883 0.117 0.000
I51.9 Heart disease, unspecified
0.880 0.120 0.000
Chapter II Neoplasms
0.879 0.121 0.000
Z95.9 Presence of cardiac and vascular implant and graft, unspecified
0.878 0.122 0.000
J40-J47 Chronic lower respiratory diseases
0.878 0.122 0.000
I47 Paroxysmal tachycardia
0.872 0.128 0.000
Z94 Transplanted organ and tissue status
0.872 0.128 0.000
I77.1 Stricture of artery
0.864 0.136 0.000
I22 Subsequent myocardial infarction
0.854 0.146 0.000
H65-H75 Diseases of middle ear and mastoid
0.851 0.149 0.000
I74 Arterial embolism and thrombosis
0.851 0.149 0.000
I42 Cardiomyopathy
0.848 0.152 0.000
Z72 Problems related to lifestyle
0.846 0.154 0.000
M86-M90 Other osteopathies
0.845 0.155 0.000
I12 Hypertensive renal disease
0.843 0.157 0.000
H90-H95 Other disorders of ear
0.842 0.158 0.000
H10-H13 Disorders of conjunctiva
0.842 0.158 0.000
E87.6 Hypokalaemia
0.839 0.161 0.000
Z95.2 Presence of prosthetic heart valve
0.839 0.161 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.838 0.162 0.000
H60-H62 Diseases of external ear
0.834 0.166 0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.833 0.167 0.000
I50.0 Congestive heart failure
0.831 0.169 0.000
Z93 Artificial opening status
0.830 0.170 0.000
I21.0 Acute transmural myocardial infarction of anterior wall
0.829 0.171 0.000
I46.0 Cardiac arrest with successful resuscitation
0.826 0.174 0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified
0.825 0.175 0.000
I50.9 Heart failure, unspecified
0.822 0.178 0.000
I21.9 Acute myocardial infarction, unspecified
0.819 0.181 0.000
Chapter XXII Codes for special purposes
0.816 0.184 0.000
Z89 Acquired absence of limb
0.812 0.188 0.000
G70-G73 Diseases of myoneural junction and muscle
0.808 0.192 0.000
I35.8 Other aortic valve disorders
0.804 0.196 0.000
J47 Bronchiectasis
0.804 0.196 0.000
I77.6 Arteritis, unspecified
0.802 0.198 0.000
I35.2 Aortic (valve) stenosis with insufficiency
0.802 0.198 0.000
Z72.0 Tobacco use
0.801 0.199 0.000
I72 Other aneurysm
0.800 0.200 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.799 0.201 0.000
E78.8 Other disorders of lipoprotein metabolism
0.799 0.201 0.000
Z82.6 Family history of arthritis and other diseases of the musculoskeletal system and connective tissue
0.794 0.206 0.000
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified
0.792 0.208 0.000
Z97 Presence of other devices
0.791 0.209 0.000
J30-J39 Other diseases of upper respiratory tract
0.790 0.210 0.000
I12.9 Hypertensive renal disease without renal failure
0.788 0.212 0.000
I51.6 Cardiovascular disease, unspecified
0.788 0.212 0.000
G43.1 Migraine with aura [classical migraine]
0.788 0.212 0.000
G62 Other polyneuropathies
0.786 0.214 0.000
Z75 Problems related to medical facilities and other health care
0.786 0.214 0.000
A30-A49 Other bacterial diseases
0.785 0.215 0.000
Z82.3 Family history of stroke
0.782 0.218 0.000
M47.99 Spondylosis, unspecified (Site unspecified)
0.782 0.218 0.000
J42 Unspecified chronic bronchitis
0.782 0.218 0.000
I63 Cerebral infarction
0.780 0.220 0.000
Z71.3 Dietary counselling and surveillance
0.775 0.225 0.000
M47.90 Spondylosis, unspecified (Multiple sites in spine)
0.774 0.226 0.000
J15 Bacterial pneumonia, not elsewhere classified
0.774 0.226 0.000
A00-A09 Intestinal infectious diseases
0.772 0.228 0.000
I51.8 Other ill-defined heart diseases
0.770 0.230 0.000
I25.5 Ischaemic cardiomyopathy
0.768 0.232 0.000
H30-H36 Disorders of choroid and retina
0.767 0.233 0.000
I05-I09 Chronic rheumatic heart diseases
0.765 0.235 0.000
I20.1 Angina pectoris with documented spasm
0.765 0.235 0.000
J60-J70 Lung diseases due to external agents
0.764 0.236 0.000
E40-E46 Malnutrition
0.764 0.236 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.763 0.237 0.000
H11 Other disorders of conjunctiva
0.762 0.238 0.000
Z95.3 Presence of xenogenic heart valve
0.762 0.238 0.000
H61 Other disorders of external ear
0.760 0.240 0.000
I25.3 Aneurysm of heart
0.758 0.242 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.756 0.243 0.000
J20-J22 Other acute lower respiratory infections
0.755 0.245 0.000
I35.9 Aortic valve disorder, unspecified
0.755 0.245 0.000
Z94.8 Other transplanted organ and tissue status
0.754 0.246 0.000
M60-M63 Disorders of muscles
0.754 0.246 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.753 0.247 0.000
E78.4 Other hyperlipidaemia
0.753 0.247 0.000
I51.7 Cardiomegaly
0.753 0.247 0.000
Z82.0 Family history of epilepsy and other diseases of the nervous system
0.752 0.248 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.752 0.248 0.000
I47.1 Supraventricular tachycardia
0.751 0.249 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.747 0.253 0.000
H71 Cholesteatoma of middle ear
0.745 0.255 0.000
J14 Pneumonia due to Haemophilus influenzae
0.744 0.256 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.744 0.256 0.000
I30 Acute pericarditis
0.743 0.257 0.000
Z71.9 Counselling, unspecified
0.742 0.258 0.000
G90-G99 Other disorders of the nervous system
0.740 0.260 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.740 0.260 0.000
I42.9 Cardiomyopathy, unspecified
0.739 0.261 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.738 0.262 0.000
H90 Conductive and sensorineural hearing loss
0.738 0.262 0.000
M45 Ankylosing spondylitis
0.737 0.263 0.000
I34 Nonrheumatic mitral valve disorders
0.737 0.263 0.000
B99-B99 Other infectious diseases
0.737 0.263 0.000
E73 Lactose intolerance
0.736 0.264 0.000
Z99.1 Dependence on respirator
0.735 0.265 0.000
Q60-Q64 Congenital malformations of the urinary system
0.734 0.266 0.000
I33 Acute and subacute endocarditis
0.734 0.266 0.000
I37 Pulmonary valve disorders
0.733 0.267 0.000
I22.9 Subsequent myocardial infarction of unspecified site
0.732 0.268 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.731 0.269 0.000
I77.8 Other specified disorders of arteries and arterioles
0.731 0.269 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.730 0.270 0.000
Z84 Family history of other conditions
0.728 0.272 0.000
C90 Multiple myeloma and malignant plasma cell neoplasms
0.727 0.273 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.725 0.275 0.000
I67 Other cerebrovascular diseases
0.725 0.275 0.000
J18.0 Bronchopneumonia, unspecified
0.723 0.277 0.000
C64-C68 Malignant neoplasms of urinary tract
0.723 0.277 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.722 0.278 0.000
I42.6 Alcoholic cardiomyopathy
0.722 0.278 0.000
I38 Endocarditis, valve unspecified
0.721 0.278 0.000
J00-J06 Acute upper respiratory infections
0.721 0.279 0.000
C51-C58 Malignant neoplasms of female genital organs
0.720 0.280 0.000
E78.2 Mixed hyperlipidaemia
0.718 0.282 0.000
Z74 Problems related to care-provider dependency
0.718 0.282 0.000
I25.6 Silent myocardial ischaemia
0.717 0.283 0.000
I25.4 Coronary artery aneurysm
0.717 0.283 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.717 0.283 0.000
I23 Certain current complications following acute myocardial infarction
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
E78.6 Lipoprotein deficiency
0.717 0.283 0.000
E78.3 Hyperchylomicronaemia
0.717 0.283 0.000
E78.1 Pure hyperglyceridaemia
0.717 0.283 0.000
H25.0 Senile incipient cataract
0.717 0.283 0.000
E85 Amyloidosis
0.717 0.283 0.000
E84 Cystic fibrosis
0.717 0.283 0.000
E79 Disorders of purine and pyrimidine metabolism
0.717 0.283 0.000
E77 Disorders of glycoprotein metabolism
0.717 0.283 0.000
E76 Disorders of glycosaminoglycan metabolism
0.717 0.283 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.717 0.283 0.000
E74 Other disorders of carbohydrate metabolism
0.717 0.283 0.000
E72 Other disorders of amino-acid metabolism
0.717 0.283 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.717 0.283 0.000
E70 Disorders of aromatic amino-acid metabolism
0.717 0.283 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.717 0.283 0.000
I52 Other heart disorders in diseases classified elsewhere
0.717 0.283 0.000
I48 Atrial fibrillation and flutter
0.717 0.283 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.717 0.283 0.000
I41 Myocarditis in diseases classified elsewhere
0.717 0.283 0.000
I40 Acute myocarditis
0.717 0.283 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.717 0.283 0.000
I36 Nonrheumatic tricuspid valve disorders
0.717 0.283 0.000
I32 Pericarditis in diseases classified elsewhere
0.717 0.283 0.000
Z82.8 Family history of other disabilities and chronic diseases leading to disablement, not elsewhere classified
0.717 0.283 0.000
Z82.7 Family history of congenital malformations, deformations and chromosomal abnormalities
0.717 0.283 0.000
Z82.5 Family history of asthma and other chronic lower respiratory diseases
0.717 0.283 0.000
Z82.2 Family history of deafness and hearing loss
0.717 0.283 0.000
Z82.1 Family history of blindness and visual loss
0.717 0.283 0.000
I74.8 Embolism and thrombosis of other arteries
0.717 0.283 0.000
Z71.1 Person with feared complaint in whom no diagnosis is made
0.715 0.285 0.000
Z93.3 Colostomy status
0.715 0.285 0.000
E87.4 Mixed disorder of acid-base balance
0.714 0.286 0.000
E87.3 Alkalosis
0.714 0.286 0.000
I21.2 Acute transmural myocardial infarction of other sites
0.713 0.287 0.000
M89 Other disorders of bone
0.711 0.289 0.000
I47.2 Ventricular tachycardia
0.710 0.290 0.000
M05-M14 Inflammatory polyarthropathies
0.710 0.290 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.709 0.291 0.000
G63 Polyneuropathy in diseases classified elsewhere
0.709 0.291 0.000
I21.X Presumed acute myicardial infaction (unconfirmed)
0.709 0.291 0.000
I21.3 Acute transmural myocardial infarction of unspecified site
0.709 0.291 0.000
A04 Other bacterial intestinal infections
0.709 0.291 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.707 0.293 0.000
M91-M94 Chondropathies
0.707 0.293 0.000
E78.9 Disorder of lipoprotein metabolism, unspecified
0.706 0.293 0.000
E83 Disorders of mineral metabolism
0.705 0.295 0.000
I71.0 Dissection of aorta [any part]
0.703 0.297 0.000
H92 Otalgia and effusion of ear
0.701 0.299 0.000
E88 Other metabolic disorders
0.701 0.299 0.000
Z76 Persons encountering health services in other circumstances
0.700 0.299 0.000
Z70 Counselling related to sexual attitude, behaviour and orientation
0.700 0.299 0.000
Z81 Family history of mental and behavioural disorders
0.699 0.301 0.000
E87.5 Hyperkalaemia
0.699 0.301 0.000
D10-D36 Benign neoplasms
0.698 0.302 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.697 0.303 0.000
I15 Secondary hypertension
0.696 0.304 0.000
I13 Hypertensive heart and renal disease
0.696 0.304 0.000
I24.1 Dressler's syndrome
0.695 0.305 0.000
I77.5 Necrosis of artery
0.695 0.305 0.000
I77.4 Coeliac artery compression syndrome
0.695 0.305 0.000
I77.3 Arterial fibromuscular dysplasia
0.695 0.305 0.000
I77.2 Rupture of artery
0.695 0.305 0.000
I77.0 Arteriovenous fistula, acquired
0.695 0.305 0.000
Z72.2 Drug use
0.695 0.305 0.000
G70 Myasthenia gravis and other myoneural disorders
0.693 0.307 0.000
J10 Influenza due to identified influenza virus
0.692 0.308 0.000
J35 Chronic diseases of tonsils and adenoids
0.691 0.309 0.000
Q80-Q89 Other congenital malformations
0.690 0.310 0.000
G61 Inflammatory polyneuropathy
0.690 0.310 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.690 0.310 0.000
I51.5 Myocardial degeneration
0.689 0.311 0.000
I51.4 Myocarditis, unspecified
0.689 0.311 0.000
I51.3 Intracardiac thrombosis, not elsewhere classified
0.689 0.311 0.000
I51.2 Rupture of papillary muscle, not elsewhere classified
0.689 0.311 0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.689 0.311 0.000
I51.0 Cardiac septal defect, acquired
0.689 0.311 0.000
M88 Paget's disease of bone [osteitis deformans]
0.689 0.311 0.000
G30-G32 Other degenerative diseases of the nervous system
0.688 0.312 0.000
G45 Transient cerebral ischaemic attacks and related syndromes
0.686 0.314 0.000
Z94.0 Kidney transplant status
0.684 0.315 0.000
Z95.4 Presence of other heart-valve replacement
0.684 0.316 0.000
E65-E68 Obesity and other hyperalimentation
0.684 0.316 0.000
H55-H59 Other disorders of eye and adnexa
0.682 0.318 0.000
J17 Pneumonia in diseases classified elsewhere
0.681 0.319 0.000
J16 Pneumonia due to other infectious organisms, not elsewhere classified
0.681 0.319 0.000
J12 Viral pneumonia, not elsewhere classified
0.681 0.319 0.000
J09 Influenza due to certain identified influenza virus
0.681 0.319 0.000
A46 Erysipelas
0.681 0.319 0.000
C73 Malignant neoplasm of thyroid gland
0.680 0.320 0.000
J40 Bronchitis, not specified as acute or chronic
0.680 0.320 0.000
I22.8 Subsequent myocardial infarction of other sites
0.678 0.322 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.677 0.322 0.000
Q50-Q56 Congenital malformations of genital organs
0.677 0.323 0.000
M00-M03 Infectious arthropathies
0.677 0.323 0.000
D27 Benign neoplasm of ovary
0.677 0.323 0.000
Z71.7 Human immunodeficiency virus [HIV] counselling
0.677 0.323 0.000
Z71.6 Tobacco abuse counselling
0.677 0.323 0.000
Z71.5 Drug abuse counselling and surveillance
0.677 0.323 0.000
Z71.4 Alcohol abuse counselling and surveillance
0.677 0.323 0.000
Z71.2 Person consulting for explanation of investigation findings
0.677 0.323 0.000
Z71.0 Person consulting on behalf of another person
0.677 0.323 0.000
H61.2 Impacted cerumen
0.676 0.324 0.000
G62.8 Other specified polyneuropathies
0.676 0.324 0.000
G46 Vascular syndromes of brain in cerebrovascular diseases
0.674 0.325 0.000
G41 Status epilepticus
0.674 0.325 0.000
A80-A89 Viral infections of the central nervous system
0.673 0.327 0.000
M87 Osteonecrosis
0.671 0.329 0.000
J36 Peritonsillar abscess
0.670 0.330 0.000
I45 Other conduction disorders
0.670 0.330 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.670 0.330 0.000
M80-M85 Disorders of bone density and structure
0.670 0.330 0.000
H74 Other disorders of middle ear and mastoid
0.670 0.330 0.000
G47 Sleep disorders
0.670 0.330 0.000
I63.8 Other cerebral infarction
0.669 0.331 0.000
H35 Other retinal disorders
0.668 0.332 0.000
I11 Hypertensive heart disease
0.667 0.333 0.000
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries
0.667 0.333 0.000
C71 Malignant neoplasm of brain
0.667 0.333 0.000
B35-B49 Mycoses
0.665 0.334 0.000
H73 Other disorders of tympanic membrane
0.665 0.335 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.664 0.336 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.664 0.336 0.000
B65-B83 Helminthiases
0.664 0.336 0.000
B50-B64 Protozoal diseases
0.664 0.336 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.664 0.336 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.664 0.336 0.000
A75-A79 Rickettsioses
0.664 0.336 0.000
A70-A74 Other diseases caused by chlamydiae
0.664 0.336 0.000
A65-A69 Other spirochaetal diseases
0.664 0.336 0.000
A20-A28 Certain zoonotic bacterial diseases
0.664 0.336 0.000
A15-A19 Tuberculosis
0.664 0.336 0.000
J31 Chronic rhinitis, nasopharyngitis and pharyngitis
0.664 0.336 0.000
G60 Hereditary and idiopathic neuropathy
0.664 0.336 0.000
G40 Epilepsy
0.663 0.337 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.663 0.337 0.000
G43.8 Other migraine
0.662 0.338 0.000
G43.3 Complicated migraine
0.662 0.338 0.000
G43.2 Status migrainosus
0.662 0.338 0.000
G43.0 Migraine without aura [common migraine]
0.662 0.338 0.000
B07 Viral warts
0.661 0.339 0.000
J18.8 Other pneumonia, organism unspecified
0.661 0.339 0.000
J18.2 Hypostatic pneumonia, unspecified
0.661 0.339 0.000
J11 Influenza, virus not identified
0.660 0.339 0.000
I70 Atherosclerosis
0.660 0.340 0.000
Z93.0 Tracheostomy status
0.660 0.340 0.000
Z93.4 Other artificial openings of gastro-intestinal tract status
0.660 0.340 0.000
M49 Spondylopathies in diseases classified elsewhere
0.659 0.341 0.000
I62 Other nontraumatic intracranial haemorrhage
0.659 0.341 0.000
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.658 0.342 0.000
I71.2 Thoracic aortic aneurysm, without mention of rupture
0.657 0.342 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.657 0.343 0.000
Z99.2 Dependence on renal dialysis
0.656 0.344 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.655 0.345 0.000
J61 Pneumoconiosis due to asbestos and other mineral fibres
0.654 0.346 0.000
A04.8 Other specified bacterial intestinal infections
0.653 0.347 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.653 0.347 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.653 0.347 0.000
Q35-Q37 Cleft lip and cleft palate
0.653 0.347 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.653 0.347 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.653 0.347 0.000
Q00-Q07 Congenital malformations of the nervous system
0.653 0.347 0.000
C34 Malignant neoplasm of bronchus and lung
0.653 0.347 0.000
H69 Other disorders of Eustachian tube
0.652 0.348 0.000
M47.0 Anterior spinal and vertebral artery compression syndromes
0.652 0.348 0.000
J46 Status asthmaticus
0.651 0.348 0.000
H10 Conjunctivitis
0.651 0.349 0.000
Z75.1 Person awaiting admission to adequate facility elsewhere
0.649 0.351 0.000
B25-B34 Other viral diseases
0.649 0.351 0.000
M47.98 Spondylosis, unspecified (Sacral and sacrococcygeal region)
0.648 0.351 0.000
M47.95 Spondylosis, unspecified (Thoracolumbar region)
0.648 0.351 0.000
M47.94 Spondylosis, unspecified (Thoracic region)
0.648 0.351 0.000
M47.93 Spondylosis, unspecified (Cervicothoracic region)
0.648 0.351 0.000
M47.91 Spondylosis, unspecified (Occipito-atlanto-axial region)
0.648 0.351 0.000
I72.4 Aneurysm of artery of lower extremity
0.648 0.352 0.000
G44 Other headache syndromes
0.647 0.353 0.000
Z89.4 Acquired absence of foot and ankle
0.647 0.353 0.000
C90.0 Multiple myeloma
0.647 0.353 0.000
I71.8 Aortic aneurysm of unspecified site, ruptured
0.646 0.354 0.000
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture
0.646 0.354 0.000
I71.5 Thoracoabdominal aortic aneurysm, ruptured
0.646 0.354 0.000
I71.3 Abdominal aortic aneurysm, ruptured
0.646 0.354 0.000
I71.1 Thoracic aortic aneurysm, ruptured
0.646 0.354 0.000
J95-J99 Other diseases of the respiratory system
0.646 0.354 0.000
H28 Cataract and other disorders of lens in diseases classified elsewhere
0.646 0.354 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.644 0.355 0.000
B15-B19 Viral hepatitis
0.643 0.357 0.000
I74.5 Embolism and thrombosis of iliac artery
0.643 0.357 0.000
I46.1 Sudden cardiac death, so described
0.643 0.357 0.000
H93 Other disorders of ear, not elsewhere classified
0.641 0.359 0.000
H65 Nonsuppurative otitis media
0.640 0.360 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.640 0.360 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.640 0.360 0.000
G64 Other disorders of peripheral nervous system
0.639 0.361 0.000
H11.3 Conjunctival haemorrhage
0.636 0.364 0.000
H25.2 Senile cataract, morgagnian type
0.636 0.364 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.635 0.364 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.635 0.365 0.000
M47.8 Other spondylosis
0.635 0.365 0.000
G62.9 Polyneuropathy, unspecified
0.635 0.365 0.000
E20-E35 Disorders of other endocrine glands
0.633 0.366 0.000
B08 Other viral infections characterised by skin and mucous membrane lesions, not elsewhere classified
0.633 0.367 0.000
D17 Benign lipomatous neoplasm
0.632 0.368 0.000
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries
0.632 0.368 0.000
I35.1 Aortic (valve) insufficiency
0.631 0.369 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.630 0.370 0.000
I65.2 Occlusion and stenosis of carotid artery
0.630 0.370 0.000
D00-D09 In situ neoplasms
0.630 0.370 0.000
C81 Hodgkin's disease
0.630 0.370 0.000
J41 Simple and mucopurulent chronic bronchitis
0.629 0.370 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.629 0.371 0.000
Z89.5 Acquired absence of leg at or below knee
0.629 0.371 0.000
M47.1 Other spondylosis with myelopathy
0.628 0.371 0.000
H90.6 Mixed conductive and sensorineural hearing loss, bilateral
0.629 0.371 0.000
Z93.5 Cystostomy status
0.628 0.372 0.000
I46.9 Cardiac arrest, unspecified
0.628 0.372 0.000
H80-H83 Diseases of inner ear
0.628 0.372 0.000
H27 Other disorders of lens
0.626 0.373 0.000
I47.0 Reentry ventricular arrhythmia
0.625 0.374 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.626 0.374 0.000
Z94.9 Transplanted organ and tissue status, unspecified
0.625 0.375 0.000
Z94.7 Corneal transplant status
0.625 0.375 0.000
Z94.6 Bone transplant status
0.625 0.375 0.000
Z94.5 Skin transplant status
0.625 0.375 0.000
Z94.3 Heart and lungs transplant status
0.625 0.375 0.000
Z94.2 Lung transplant status
0.625 0.375 0.000
Z94.1 Heart transplant status
0.625 0.375 0.000
I67.8 Other specified cerebrovascular diseases
0.624 0.376 0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.624 0.376 0.000
Z97.4 Presence of external hearing-aid
0.623 0.377 0.000
I42.8 Other cardiomyopathies
0.623 0.377 0.000
J15.2 Pneumonia due to staphylococcus
0.622 0.378 0.000
A49 Bacterial infection of unspecified site
0.621 0.379 0.000
J39 Other diseases of upper respiratory tract
0.619 0.381 0.000
C54 Malignant neoplasm of corpus uteri
0.619 0.381 0.000
M47.97 Spondylosis, unspecified (Lumbosacral region)
0.618 0.381 0.000
Z94.4 Liver transplant status
0.618 0.382 0.000
Z98 Other postsurgical states
0.617 0.383 0.000
C91 Lymphoid leukaemia
0.617 0.383 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.617 0.383 0.000
Z97.0 Presence of artificial eye
0.617 0.383 0.000
H90.3 Sensorineural hearing loss, bilateral
0.616 0.384 0.000
I08 Multiple valve diseases
0.616 0.384 0.000
M48 Other spondylopathies
0.615 0.385 0.000
G95 Other diseases of spinal cord
0.614 0.386 0.000
C92 Myeloid leukaemia
0.613 0.387 0.000
I22.0 Subsequent myocardial infarction of anterior wall
0.612 0.388 0.000
J22 Unspecified acute lower respiratory infection
0.611 0.389 0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere
0.610 0.390 0.000
H70 Mastoiditis and related conditions
0.610 0.390 0.000
H68 Eustachian salpingitis and obstruction
0.610 0.390 0.000
H67 Otitis media in diseases classified elsewhere
0.610 0.390 0.000
I74.9 Embolism and thrombosis of unspecified artery
0.610 0.390 0.000
I74.4 Embolism and thrombosis of arteries of extremities, unspecified
0.610 0.390 0.000
I74.1 Embolism and thrombosis of other and unspecified parts of aorta
0.610 0.390 0.000
I74.0 Embolism and thrombosis of abdominal aorta
0.610 0.390 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.610 0.390 0.000
G70.0 Myasthenia gravis
0.610 0.390 0.000
H11.4 Other conjunctival vascular disorders and cysts
0.610 0.390 0.000
H31 Other disorders of choroid
0.610 0.390 0.000
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.609 0.391 0.000
I42.7 Cardiomyopathy due to drugs and other external agents
0.608 0.392 0.000
I42.5 Other restrictive cardiomyopathy
0.608 0.392 0.000
I42.4 Endocardial fibroelastosis
0.608 0.392 0.000
I42.3 Endomyocardial (eosinophilic) disease
0.608 0.392 0.000
M45.X9 Ankylosing spondylitis (Site unspecified)
0.607 0.393 0.000
Z72.9 Problem related to lifestyle, unspecified
0.607 0.393 0.000
Z72.8 Other problems related to lifestyle
0.607 0.393 0.000
Z72.6 Gambling and betting
0.607 0.393 0.000
Z72.5 High-risk sexual behaviour
0.607 0.393 0.000
Z72.4 Inappropriate diet and eating habits
0.607 0.393 0.000
Z72.3 Lack of physical exercise
0.607 0.393 0.000
H11.9 Disorder of conjunctiva, unspecified
0.606 0.394 0.000
M47.2 Other spondylosis with radiculopathy
0.606 0.394 0.000
M90 Osteopathies in diseases classified elsewhere
0.605 0.394 0.000
M40-M43 Deforming dorsopathies
0.605 0.395 0.000
H53-H54 Visual disturbances and blindness
0.604 0.396 0.000
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified
0.604 0.396 0.000
H94 Other disorders of ear in diseases classified elsewhere
0.604 0.396 0.000
H43-H45 Disorders of vitreous body and globe
0.604 0.396 0.000
H13 Disorders of conjunctiva in diseases classified elsewhere
0.603 0.396 0.000
C64 Malignant neoplasm of kidney, except renal pelvis
0.603 0.397 0.000
M86 Osteomyelitis
0.602 0.398 0.000
Z97.5 Presence of (intra-uterine) contraceptive device
0.602 0.398 0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.601 0.399 0.000
C95 Leukaemia of unspecified cell type
0.601 0.399 0.000
C94 Other leukaemias of specified cell type
0.601 0.399 0.000
C93 Monocytic leukaemia
0.601 0.399 0.000
C88 Malignant immunoproliferative diseases
0.601 0.399 0.000
C86 Other specified types of T/NK-cell lymphoma
0.601 0.399 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.601 0.399 0.000
Z57 Occupational exposure to risk-factors
0.601 0.399 0.000
M46 Other inflammatory spondylopathies
0.601 0.399 0.000
B99 Other and unspecified infectious diseases
0.601 0.399 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.600 0.399 0.000
I72.8 Aneurysm of other specified arteries
0.599 0.401 0.000
Z63 Other problems related to primary support group, including family circumstances
0.599 0.401 0.000
H62 Disorders of external ear in diseases classified elsewhere
0.598 0.402 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.597 0.403 0.000
H61.8 Other specified disorders of external ear
0.597 0.403 0.000
H52 Disorders of refraction and accommodation
0.597 0.403 0.000
M60 Myositis
0.596 0.404 0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.596 0.404 0.000
Z93.9 Artificial opening status, unspecified
0.595 0.405 0.000
Z93.8 Other artificial opening status
0.595 0.405 0.000
E46 Unspecified protein-energy malnutrition
0.595 0.405 0.000
I61 Intracerebral haemorrhage
0.593 0.407 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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