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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs56005336
log Bayes Factor = 20.0755
Chromosome 6   position 34,144,189  (GRCh37) Explore rs56005336 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
N40 Hyperplasia of prostate
1.000 0.000 0.000
N40-N51 Diseases of male genital organs
1.000 0.000 0.000
Chapter XIV Diseases of the genitourinary system
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
1.000 0.000 0.000
I20-I25 Ischaemic heart diseases
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
N80-N98 Noninflammatory disorders of female genital tract
1.000 0.000 0.000
I77 Other disorders of arteries and arterioles
0.998 0.002 0.000
I10-I15 Hypertensive diseases
0.997 0.003 0.000
E20-E35 Disorders of other endocrine glands
0.996 0.004 0.000
I10 Essential (primary) hypertension
0.996 0.004 0.000
Chapter VI Diseases of the nervous system
0.995 0.005 0.000
I30-I52 Other forms of heart disease
0.994 0.006 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.994 0.006 0.000
N80 Endometriosis
0.991 0.009 0.000
I77.1 Stricture of artery
0.990 0.010 0.000
G57 Mononeuropathies of lower limb
0.989 0.011 0.000
G57.6 Lesion of plantar nerve
0.985 0.015 0.000
N20-N23 Urolithiasis
0.985 0.015 0.000
N84 Polyp of female genital tract
0.983 0.017 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.983 0.017 0.000
N86 Erosion and ectropion of cervix uteri
0.979 0.021 0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere
0.978 0.022 0.000
N84.1 Polyp of cervix uteri
0.969 0.031 0.000
I21 Acute myocardial infarction
0.969 0.031 0.000
I24 Other acute ischaemic heart diseases
0.968 0.032 0.000
M20-M25 Other joint disorders
0.968 0.032 0.000
N80.0 Endometriosis of uterus
0.967 0.033 0.000
E10-E14 Diabetes mellitus
0.963 0.037 0.000
I71 Aortic aneurysm and dissection
0.962 0.038 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.960 0.040 0.000
N41 Inflammatory diseases of prostate
0.959 0.041 0.000
I77.6 Arteritis, unspecified
0.956 0.044 0.000
M45-M49 Spondylopathies
0.952 0.048 0.000
N21 Calculus of lower urinary tract
0.950 0.050 0.000
N47 Redundant prepuce, phimosis and paraphimosis
0.949 0.051 0.000
N20 Calculus of kidney and ureter
0.945 0.055 0.000
I25 Chronic ischaemic heart disease
0.944 0.056 0.000
G55.1 Nerve root and plexus compressions in intervertebral disk disorders
0.944 0.056 0.000
I25.1 Atherosclerotic heart disease
0.941 0.059 0.000
I24.8 Other forms of acute ischaemic heart disease
0.940 0.060 0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.940 0.060 0.000
I21.9 Acute myocardial infarction, unspecified
0.935 0.065 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.929 0.071 0.000
I34 Nonrheumatic mitral valve disorders
0.928 0.072 0.000
N21.0 Calculus in bladder
0.925 0.075 0.000
E21.0 Primary hyperparathyroidism
0.922 0.078 0.000
M25 Other joint disorders, not elsewhere classified
0.916 0.084 0.000
N41.1 Chronic prostatitis
0.916 0.084 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.915 0.085 0.000
E00-E07 Disorders of thyroid gland
0.910 0.090 0.000
N50 Other disorders of male genital organs
0.908 0.092 0.000
M47 Spondylosis
0.908 0.092 0.000
E70-E90 Metabolic disorders
0.907 0.093 0.000
M40-M43 Deforming dorsopathies
0.903 0.097 0.000
N83 Noninflammatory disorders of ovary, Fallopian tube and broad ligament
0.902 0.098 0.000
E11 Non-insulin-dependent diabetes mellitus
0.901 0.099 0.000
M21 Other acquired deformities of limbs
0.900 0.100 0.000
I05-I09 Chronic rheumatic heart diseases
0.900 0.100 0.000
N80.8 Other endometriosis
0.900 0.100 0.000
E27 Other disorders of adrenal gland
0.897 0.103 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.891 0.109 0.000
E11.9 Without complications
0.889 0.111 0.000
M24 Other specific joint derangements
0.889 0.111 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.886 0.114 0.000
R42 Dizziness and giddiness
0.883 0.117 0.000
N94 Pain and other conditions associated with female genital organs and menstrual cycle
0.882 0.118 0.000
M47.8 Other spondylosis
0.881 0.119 0.000
I74 Arterial embolism and thrombosis
0.881 0.119 0.000
I20 Angina pectoris
0.880 0.120 0.000
I21.0 Acute transmural myocardial infarction of anterior wall
0.879 0.121 0.000
N20.1 Calculus of ureter
0.878 0.122 0.000
I34.0 Mitral (valve) insufficiency
0.877 0.123 0.000
N80.9 Endometriosis, unspecified
0.873 0.127 0.000
D60-D64 Aplastic and other anaemias
0.873 0.127 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.871 0.129 0.000
N50.8 Other specified disorders of male genital organs
0.867 0.133 0.000
Chapter V Mental and behavioural disorders
0.862 0.138 0.000
I51 Complications and ill-defined descriptions of heart disease
0.861 0.139 0.000
I21.2 Acute transmural myocardial infarction of other sites
0.859 0.141 0.000
M41 Scoliosis
0.859 0.141 0.000
I22 Subsequent myocardial infarction
0.856 0.144 0.000
E14 Unspecified diabetes mellitus
0.851 0.149 0.000
I72 Other aneurysm
0.850 0.150 0.000
N84.2 Polyp of vagina
0.848 0.152 0.000
E05.9 Thyrotoxicosis, unspecified
0.848 0.152 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.847 0.153 0.000
N41.0 Acute prostatitis
0.846 0.154 0.000
N20.2 Calculus of kidney with calculus of ureter
0.843 0.157 0.000
D62 Acute posthaemorrhagic anaemia
0.842 0.158 0.000
M47.82 Other spondylosis (Cervical region)
0.841 0.159 0.000
I38 Endocarditis, valve unspecified
0.837 0.163 0.000
G90-G99 Other disorders of the nervous system
0.837 0.163 0.000
G55.2 Nerve root and plexus compressions in spondylosis
0.833 0.167 0.000
N83.2 Other and unspecified ovarian cysts
0.832 0.168 0.000
M25.5 Pain in joint
0.829 0.171 0.000
I35 Nonrheumatic aortic valve disorders
0.827 0.173 0.000
R79 Other abnormal findings of blood chemistry
0.825 0.175 0.000
M41.9 Scoliosis, unspecified
0.819 0.181 0.000
M45 Ankylosing spondylitis
0.819 0.181 0.000
E83 Disorders of mineral metabolism
0.818 0.182 0.000
I49 Other cardiac arrhythmias
0.818 0.182 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.816 0.184 0.000
E24 Cushing's syndrome
0.816 0.184 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.816 0.184 0.000
Chapter VIII Diseases of the ear and mastoid process
0.814 0.186 0.000
E22 Hyperfunction of pituitary gland
0.809 0.191 0.000
M25.57 Pain in joint (Ankle and foot)
0.809 0.191 0.000
Chapter XXI Factors influencing health status and contact with health services
0.804 0.196 0.000
E28 Ovarian dysfunction
0.801 0.199 0.000
N99-N99 Other disorders of the genitourinary system
0.800 0.200 0.000
I45 Other conduction disorders
0.800 0.200 0.000
M31 Other necrotising vasculopathies
0.798 0.202 0.000
G55.8 Nerve root and plexus compressions in other diseases classified elsewhere
0.798 0.202 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.796 0.204 0.000
G57.8 Other mononeuropathies of lower limb
0.789 0.211 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.789 0.211 0.000
N94.1 Dyspareunia
0.789 0.211 0.000
R79.8 Other specified abnormal findings of blood chemistry
0.787 0.213 0.000
I42 Cardiomyopathy
0.787 0.213 0.000
N84.3 Polyp of vulva
0.785 0.214 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.784 0.216 0.000
F30-F39 Mood [affective] disorders
0.784 0.216 0.000
M47.2 Other spondylosis with radiculopathy
0.783 0.217 0.000
I30 Acute pericarditis
0.781 0.219 0.000
N80.2 Endometriosis of Fallopian tube
0.778 0.222 0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.777 0.223 0.000
G20-G26 Extrapyramidal and movement disorders
0.777 0.223 0.000
I78 Diseases of capillaries
0.777 0.223 0.000
N81 Female genital prolapse
0.777 0.223 0.000
M80-M85 Disorders of bone density and structure
0.777 0.223 0.000
I50 Heart failure
0.776 0.224 0.000
M91-M94 Chondropathies
0.775 0.225 0.000
M60-M63 Disorders of muscles
0.775 0.225 0.000
N83.8 Other noninflammatory disorders of ovary, Fallopian tube and broad ligament
0.774 0.226 0.000
I51.3 Intracardiac thrombosis, not elsewhere classified
0.771 0.229 0.000
M25.8 Other specified joint disorders
0.771 0.229 0.000
N97 Female infertility
0.770 0.230 0.000
E21.3 Hyperparathyroidism, unspecified
0.769 0.231 0.000
N48 Other disorders of penis
0.769 0.231 0.000
Chapter II Neoplasms
0.767 0.233 0.000
E83.1 Disorders of iron metabolism
0.766 0.234 0.000
N84.9 Polyp of female genital tract, unspecified
0.766 0.234 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.764 0.236 0.000
M00-M03 Infectious arthropathies
0.764 0.236 0.000
M21.1 Varus deformity, not elsewhere classified
0.763 0.237 0.000
M30 Polyarteritis nodosa and related conditions
0.763 0.237 0.000
I20.1 Angina pectoris with documented spasm
0.762 0.238 0.000
G53 Cranial nerve disorders in diseases classified elsewhere
0.761 0.239 0.000
N00-N08 Glomerular diseases
0.760 0.240 0.000
I77.8 Other specified disorders of arteries and arterioles
0.758 0.241 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.757 0.243 0.000
I05 Rheumatic mitral valve diseases
0.757 0.243 0.000
Z42 Follow-up care involving plastic surgery
0.756 0.244 0.000
I11 Hypertensive heart disease
0.755 0.245 0.000
E29 Testicular dysfunction
0.753 0.247 0.000
I71.0 Dissection of aorta [any part]
0.753 0.247 0.000
E23 Hypofunction and other disorders of pituitary gland
0.752 0.248 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.751 0.249 0.000
N20.9 Urinary calculus, unspecified
0.749 0.251 0.000
N80.5 Endometriosis of intestine
0.749 0.251 0.000
N94.6 Dysmenorrhoea, unspecified
0.749 0.251 0.000
M24.1 Other articular cartilage disorders
0.748 0.252 0.000
E14.9 Without complications
0.747 0.253 0.000
M24.8 Other specific joint derangements, not elsewhere classified
0.747 0.253 0.000
I24.9 Acute ischaemic heart disease, unspecified
0.746 0.254 0.000
M47.87 Other spondylosis (Lumbosacral region)
0.745 0.255 0.000
N10-N16 Renal tubulo-interstitial diseases
0.745 0.255 0.000
E20 Hypoparathyroidism
0.744 0.256 0.000
M21.5 Acquired clawhand, clubhand, clawfoot and clubfoot
0.744 0.256 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.743 0.257 0.000
D63 Anaemia in chronic diseases classified elsewhere
0.743 0.257 0.000
M25.51 Pain in joint (Shoulder region)
0.741 0.259 0.000
M41.99 Scoliosis, unspecified (Site unspecified)
0.740 0.260 0.000
Z51 Other medical care
0.738 0.262 0.000
M41.96 Scoliosis, unspecified (Lumbar region)
0.737 0.263 0.000
I31 Other diseases of pericardium
0.736 0.264 0.000
E27.1 Primary adrenocortical insufficiency
0.736 0.264 0.000
Z43 Attention to artificial openings
0.736 0.264 0.000
E83.4 Disorders of magnesium metabolism
0.735 0.265 0.000
I49.5 Sick sinus syndrome
0.734 0.266 0.000
I77.0 Arteriovenous fistula, acquired
0.734 0.266 0.000
G00 Bacterial meningitis, not elsewhere classified
0.731 0.268 0.000
C60-C63 Malignant neoplasms of male genital organs
0.731 0.269 0.000
M47.84 Other spondylosis (Thoracic region)
0.731 0.269 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.730 0.270 0.000
M35 Other systemic involvement of connective tissue
0.729 0.271 0.000
M24.6 Ankylosis of joint
0.729 0.271 0.000
N83.5 Torsion of ovary, ovarian pedicle and Fallopian tube
0.726 0.274 0.000
I50.0 Congestive heart failure
0.725 0.275 0.000
M21.2 Flexion deformity
0.725 0.275 0.000
E05.2 Thyrotoxicosis with toxic multinodular goitre
0.725 0.275 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.723 0.277 0.000
M86-M90 Other osteopathies
0.723 0.277 0.000
M25.4 Effusion of joint
0.722 0.278 0.000
Chapter XX External causes of morbidity and mortality
0.722 0.278 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.721 0.279 0.000
F32 Depressive episode
0.720 0.280 0.000
I22.0 Subsequent myocardial infarction of anterior wall
0.718 0.282 0.000
I77.9 Disorder of arteries and arterioles, unspecified
0.718 0.282 0.000
E78.0 Pure hypercholesterolaemia
0.717 0.283 0.000
I36 Nonrheumatic tricuspid valve disorders
0.717 0.283 0.000
N51 Disorders of male genital organs in diseases classified elsewhere
0.717 0.283 0.000
N46 Male infertility
0.717 0.283 0.000
N44 Torsion of testis
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
I23 Certain current complications following acute myocardial infarction
0.717 0.283 0.000
Z42.1 Follow-up care involving plastic surgery of breast
0.717 0.283 0.000
N98 Complications associated with artificial fertilisation
0.717 0.283 0.000
N91 Absent, scanty and rare menstruation
0.717 0.283 0.000
N96 Habitual aborter
0.717 0.283 0.000
E26 Hyperaldosteronism
0.716 0.283 0.000
G56 Mononeuropathies of upper limb
0.716 0.284 0.000
I77.5 Necrosis of artery
0.716 0.284 0.000
I77.4 Coeliac artery compression syndrome
0.716 0.284 0.000
I77.3 Arterial fibromuscular dysplasia
0.716 0.284 0.000
I77.2 Rupture of artery
0.716 0.284 0.000
N42 Other disorders of prostate
0.716 0.284 0.000
I08 Multiple valve diseases
0.716 0.284 0.000
I13 Hypertensive heart and renal disease
0.715 0.285 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.714 0.286 0.000
E34 Other endocrine disorders
0.714 0.286 0.000
E32 Diseases of thymus
0.714 0.286 0.000
E31 Polyglandular dysfunction
0.714 0.286 0.000
E30 Disorders of puberty, not elsewhere classified
0.714 0.286 0.000
E25 Adrenogenital disorders
0.714 0.286 0.000
C61 Malignant neoplasm of prostate
0.713 0.287 0.000
I52 Other heart disorders in diseases classified elsewhere
0.713 0.287 0.000
I48 Atrial fibrillation and flutter
0.713 0.287 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.713 0.287 0.000
I41 Myocarditis in diseases classified elsewhere
0.713 0.287 0.000
I40 Acute myocarditis
0.713 0.287 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.713 0.287 0.000
I37 Pulmonary valve disorders
0.713 0.287 0.000
I32 Pericarditis in diseases classified elsewhere
0.713 0.287 0.000
G52 Disorders of other cranial nerves
0.712 0.287 0.000
G55.3 Nerve root and plexus compressions in other dorsopathies
0.712 0.288 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.711 0.289 0.000
N80.6 Endometriosis in cutaneous scar
0.710 0.290 0.000
N80.4 Endometriosis of rectovaginal septum and vagina
0.710 0.290 0.000
Z46 Fitting and adjustment of other devices
0.709 0.291 0.000
G57.9 Mononeuropathy of lower limb, unspecified
0.709 0.291 0.000
G57.5 Tarsal tunnel syndrome
0.709 0.291 0.000
G57.4 Lesion of medial popliteal nerve
0.709 0.291 0.000
G57.3 Lesion of lateral popliteal nerve
0.709 0.291 0.000
G57.2 Lesion of femoral nerve
0.709 0.291 0.000
G57.0 Lesion of sciatic nerve
0.709 0.291 0.000
M47.26 Other spondylosis with radiculopathy (Lumbar region)
0.708 0.292 0.000
E05.0 Thyrotoxicosis with diffuse goitre
0.708 0.292 0.000
E27.4 Other and unspecified adrenocortical insufficiency
0.707 0.293 0.000
N22 Calculus of urinary tract in diseases classified elsewhere
0.706 0.294 0.000
G25 Other extrapyramidal and movement disorders
0.706 0.294 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.706 0.294 0.000
N84.8 Polyp of other parts of female genital tract
0.705 0.295 0.000
N48.6 Balanitis xerotica obliterans
0.704 0.296 0.000
I35.9 Aortic valve disorder, unspecified
0.703 0.297 0.000
I70 Atherosclerosis
0.703 0.297 0.000
M45.X9 Ankylosing spondylitis (Site unspecified)
0.702 0.298 0.000
R77 Other abnormalities of plasma proteins
0.702 0.298 0.000
G95 Other diseases of spinal cord
0.701 0.299 0.000
I15 Secondary hypertension
0.700 0.300 0.000
I49.0 Ventricular fibrillation and flutter
0.700 0.300 0.000
I71.9 Aortic aneurysm of unspecified site, without mention of rupture
0.700 0.300 0.000
Z73 Problems related to life-management difficulty
0.699 0.301 0.000
I25.5 Ischaemic cardiomyopathy
0.698 0.302 0.000
G57.1 Meralgia paraesthetica
0.697 0.303 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.697 0.303 0.000
E11.6 With other specified complications
0.697 0.303 0.000
E27.8 Other specified disorders of adrenal gland
0.697 0.303 0.000
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.696 0.303 0.000
I20.9 Angina pectoris, unspecified
0.696 0.304 0.000
I09 Other rheumatic heart diseases
0.696 0.304 0.000
M21.17 Varus deformity, not elsewhere classified (Ankle and foot)
0.695 0.305 0.000
D45 Polycythaemia vera
0.695 0.305 0.000
E78.8 Other disorders of lipoprotein metabolism
0.695 0.305 0.000
Z51.3 Blood transfusion without reported diagnosis
0.695 0.305 0.000
I21.X Presumed acute myicardial infaction (unconfirmed)
0.694 0.306 0.000
I21.3 Acute transmural myocardial infarction of unspecified site
0.694 0.306 0.000
I24.1 Dressler's syndrome
0.694 0.306 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.694 0.306 0.000
M33 Dermatopolymyositis
0.694 0.306 0.000
M32 Systemic lupus erythematosus
0.694 0.306 0.000
R27 Other lack of coordination
0.694 0.306 0.000
M46 Other inflammatory spondylopathies
0.693 0.307 0.000
M21.4 Flat foot [pes planus] (acquired)
0.693 0.307 0.000
N85 Other noninflammatory disorders of uterus, except cervix
0.693 0.307 0.000
N13 Obstructive and reflux uropathy
0.692 0.308 0.000
M34 Systemic sclerosis
0.692 0.308 0.000
I33 Acute and subacute endocarditis
0.692 0.308 0.000
E12 Malnutrition-related diabetes mellitus
0.690 0.310 0.000
Z51.4 Preparatory care for treatment, not elsewhere classified
0.690 0.310 0.000
I71.8 Aortic aneurysm of unspecified site, ruptured
0.690 0.310 0.000
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture
0.690 0.310 0.000
I71.5 Thoracoabdominal aortic aneurysm, ruptured
0.690 0.310 0.000
I71.1 Thoracic aortic aneurysm, ruptured
0.690 0.310 0.000
R85 Abnormal findings in specimens from digestive organs and abdominal cavity
0.689 0.311 0.000
Z49 Care involving dialysis
0.689 0.311 0.000
G51 Facial nerve disorders
0.688 0.312 0.000
I72.3 Aneurysm of iliac artery
0.688 0.312 0.000
E21.5 Disorder of parathyroid gland, unspecified
0.688 0.312 0.000
E21.4 Other specified disorders of parathyroid gland
0.688 0.312 0.000
E21.2 Other hyperparathyroidism
0.688 0.312 0.000
E21.1 Secondary hyperparathyroidism, not elsewhere classified
0.688 0.312 0.000
N41.8 Other inflammatory diseases of prostate
0.688 0.312 0.000
N41.3 Prostatocystitis
0.688 0.312 0.000
N41.2 Abscess of prostate
0.688 0.312 0.000
E27.2 Addisonian crisis
0.687 0.312 0.000
M47.80 Other spondylosis (Multiple sites in spine)
0.687 0.313 0.000
I49.8 Other specified cardiac arrhythmias
0.687 0.313 0.000
E24.9 Cushing's syndrome, unspecified
0.686 0.314 0.000
E10 Insulin-dependent diabetes mellitus
0.686 0.314 0.000
G55.0 Nerve root and plexus compressions in neoplastic disease
0.686 0.314 0.000
G54 Nerve root and plexus disorders
0.685 0.315 0.000
I34.1 Mitral (valve) prolapse
0.684 0.316 0.000
R47-R49 Symptoms and signs involving speech and voice
0.684 0.316 0.000
R79.9 Abnormal finding of blood chemistry, unspecified
0.684 0.316 0.000
I22.1 Subsequent myocardial infarction of inferior wall
0.683 0.317 0.000
I35.2 Aortic (valve) stenosis with insufficiency
0.683 0.317 0.000
F33 Recurrent depressive disorder
0.683 0.317 0.000
N49 Inflammatory disorders of male genital organs, not elsewhere classified
0.682 0.317 0.000
M49 Spondylopathies in diseases classified elsewhere
0.682 0.317 0.000
E13 Other specified diabetes mellitus
0.682 0.318 0.000
R74 Abnormal serum enzyme levels
0.681 0.318 0.000
N21.9 Calculus of lower urinary tract, unspecified
0.681 0.319 0.000
N21.8 Other lower urinary tract calculus
0.681 0.319 0.000
N21.1 Calculus in urethra
0.681 0.319 0.000
I07 Rheumatic tricuspid valve diseases
0.681 0.319 0.000
N82 Fistulae involving female genital tract
0.680 0.320 0.000
N94.4 Primary dysmenorrhoea
0.678 0.321 0.000
E11.2 With renal complications
0.678 0.322 0.000
N81.6 Rectocele
0.678 0.322 0.000
Z73.3 Stress, not elsewhere classified
0.677 0.323 0.000
I25.6 Silent myocardial ischaemia
0.677 0.323 0.000
I25.4 Coronary artery aneurysm
0.677 0.323 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.677 0.323 0.000
M24.2 Disorder of ligament
0.677 0.323 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.676 0.324 0.000
E28.3 Primary ovarian failure
0.674 0.326 0.000
I74.5 Embolism and thrombosis of iliac artery
0.673 0.327 0.000
I51.9 Heart disease, unspecified
0.672 0.328 0.000
I72.8 Aneurysm of other specified arteries
0.672 0.328 0.000
Z46.6 Fitting and adjustment of urinary device
0.672 0.328 0.000
H65-H75 Diseases of middle ear and mastoid
0.671 0.329 0.000
R44 Other symptoms and signs involving general sensations and perceptions
0.671 0.329 0.000
M24.13 Other articular cartilage disorders (Forearm)
0.671 0.329 0.000
R76 Other abnormal immunological findings in serum
0.669 0.331 0.000
E27.9 Disorder of adrenal gland, unspecified
0.668 0.331 0.000
D63.8 Anaemia in other chronic diseases classified elsewhere
0.668 0.332 0.000
N90 Other noninflammatory disorders of vulva and perineum
0.668 0.332 0.000
I49.1 Atrial premature depolarisation
0.668 0.332 0.000
E14.3 With ophthalmic complications
0.667 0.333 0.000
I20.8 Other forms of angina pectoris
0.667 0.333 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.666 0.334 0.000
M21.0 Valgus deformity, not elsewhere classified
0.666 0.334 0.000
I34.9 Nonrheumatic mitral valve disorder, unspecified
0.665 0.335 0.000
I34.8 Other nonrheumatic mitral valve disorders
0.665 0.335 0.000
I34.2 Nonrheumatic mitral (valve) stenosis
0.665 0.335 0.000
F60-F69 Disorders of adult personality and behaviour
0.665 0.335 0.000
M48 Other spondylopathies
0.665 0.335 0.000
M41.8 Other forms of scoliosis
0.663 0.337 0.000
N50.0 Atrophy of testis
0.663 0.337 0.000
G25.8 Other specified extrapyramidal and movement disorders
0.662 0.337 0.000
M25.3 Other instability of joint
0.662 0.338 0.000
D80-D89 Certain disorders involving the immune mechanism
0.662 0.338 0.000
E80.4 Gilbert's syndrome
0.661 0.339 0.000
E11.1 With ketoacidosis
0.661 0.339 0.000
I45.9 Conduction disorder, unspecified
0.661 0.339 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.658 0.342 0.000
F32.3 Severe depressive episode with psychotic symptoms
0.658 0.342 0.000
N99 Postprocedural disorders of genito-urinary system, not elsewhere classified
0.657 0.343 0.000
M25.2 Flail joint
0.657 0.343 0.000
M25.1 Fistula of joint
0.657 0.343 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.655 0.344 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.655 0.345 0.000
N83.9 Noninflammatory disorder of ovary, Fallopian tube and broad ligament, unspecified
0.652 0.347 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.652 0.348 0.000
E00 Congenital iodine-deficiency syndrome
0.652 0.348 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.652 0.348 0.000
M25.9 Joint disorder, unspecified
0.651 0.349 0.000
I42.2 Other hypertrophic cardiomyopathy
0.651 0.349 0.000
N50.9 Disorder of male genital organs, unspecified
0.651 0.349 0.000
M47.1 Other spondylosis with myelopathy
0.651 0.349 0.000
M47.0 Anterior spinal and vertebral artery compression syndromes
0.651 0.349 0.000
E85 Amyloidosis
0.650 0.350 0.000
E84 Cystic fibrosis
0.650 0.350 0.000
E79 Disorders of purine and pyrimidine metabolism
0.650 0.350 0.000
E77 Disorders of glycoprotein metabolism
0.650 0.350 0.000
E76 Disorders of glycosaminoglycan metabolism
0.650 0.350 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.650 0.350 0.000
E74 Other disorders of carbohydrate metabolism
0.650 0.350 0.000
E72 Other disorders of amino-acid metabolism
0.650 0.350 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.650 0.350 0.000
E70 Disorders of aromatic amino-acid metabolism
0.650 0.350 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.650 0.350 0.000
M25.0 Haemarthrosis
0.650 0.350 0.000
R00 Abnormalities of heart beat
0.649 0.351 0.000
D55-D59 Haemolytic anaemias
0.648 0.352 0.000
G70-G73 Diseases of myoneural junction and muscle
0.647 0.352 0.000
M42 Spinal osteochondrosis
0.647 0.353 0.000
M40 Kyphosis and lordosis
0.647 0.353 0.000
N83.7 Haematoma of broad ligament
0.647 0.353 0.000
N83.6 Haematosalpinx
0.647 0.353 0.000
N83.4 Prolapse and hernia of ovary and Fallopian tube
0.647 0.353 0.000
R89 Abnormal findings in specimens from other organs, systems and tissues
0.647 0.353 0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.646 0.354 0.000
E11.8 With unspecified complications
0.646 0.354 0.000
E11.7 With multiple complications
0.646 0.354 0.000
E11.0 With coma
0.646 0.354 0.000
M25.52 Pain in joint (Upper arm)
0.646 0.354 0.000
V40-V49 Car occupant injured in transport accident
0.646 0.354 0.000
M21.9 Acquired deformity of limb, unspecified
0.645 0.354 0.000
M21.8 Other specified acquired deformities of limbs
0.645 0.354 0.000
M21.7 Unequal limb length (acquired)
0.645 0.354 0.000
I06 Rheumatic aortic valve diseases
0.645 0.354 0.000
I71.3 Abdominal aortic aneurysm, ruptured
0.645 0.355 0.000
M21.3 Wrist or foot drop (acquired)
0.645 0.355 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.644 0.356 0.000
E27.5 Adrenomedullary hyperfunction
0.643 0.357 0.000
E27.3 Drug-induced adrenocortical insufficiency
0.643 0.357 0.000
E27.0 Other adrenocortical overactivity
0.643 0.357 0.000
I72.4 Aneurysm of artery of lower extremity
0.643 0.357 0.000
D47.1 Chronic myeloproliferative disease
0.642 0.358 0.000
I47 Paroxysmal tachycardia
0.641 0.359 0.000
Z51.0 Radiotherapy session
0.641 0.359 0.000
F80-F89 Disorders of psychological development
0.640 0.359 0.000
I45.2 Bifascicular block
0.639 0.361 0.000
R46 Symptoms and signs involving appearance and behaviour
0.639 0.361 0.000
R43 Disturbances of smell and taste
0.639 0.361 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.638 0.362 0.000
E78.4 Other hyperlipidaemia
0.638 0.362 0.000
M24.9 Joint derangement, unspecified
0.637 0.363 0.000
M24.7 Protrusio acetabuli
0.637 0.363 0.000
M24.5 Contracture of joint
0.637 0.363 0.000
M24.3 Pathological dislocation and subluxation of joint, not elsewhere classified
0.637 0.363 0.000
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.637 0.363 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.636 0.364 0.000
M84 Disorders of continuity of bone
0.635 0.365 0.000
I22.8 Subsequent myocardial infarction of other sites
0.635 0.365 0.000
E05.8 Other thyrotoxicosis
0.635 0.365 0.000
E05.5 Thyroid crisis or storm
0.635 0.365 0.000
E05.4 Thyrotoxicosis factitia
0.635 0.365 0.000
E05.3 Thyrotoxicosis from ectopic thyroid tissue
0.635 0.365 0.000
E05.1 Thyrotoxicosis with toxic single thyroid nodule
0.635 0.365 0.000
G90 Disorders of autonomic nervous system
0.635 0.365 0.000
M31.3 Wegener's granulomatosis
0.633 0.367 0.000
N94.5 Secondary dysmenorrhoea
0.632 0.368 0.000
N94.2 Vaginismus
0.632 0.368 0.000
N94.0 Mittelschmerz
0.632 0.368 0.000
M21.57 Acquired clawhand, clubhand, clawfoot and clubfoot (Ankle and foot)
0.632 0.368 0.000
M47.88 Other spondylosis (Sacral and sacrococcygeal region)
0.632 0.368 0.000
M47.85 Other spondylosis (Thoracolumbar region)
0.632 0.368 0.000
M47.83 Other spondylosis (Cervicothoracic region)
0.632 0.368 0.000
M47.81 Other spondylosis (Occipito-atlanto-axial region)
0.632 0.368 0.000
I74.9 Embolism and thrombosis of unspecified artery
0.632 0.368 0.000
I74.8 Embolism and thrombosis of other arteries
0.632 0.368 0.000
I74.4 Embolism and thrombosis of arteries of extremities, unspecified
0.632 0.368 0.000
I74.1 Embolism and thrombosis of other and unspecified parts of aorta
0.632 0.368 0.000
I74.0 Embolism and thrombosis of abdominal aorta
0.632 0.368 0.000
M31.6 Other giant cell arteritis
0.632 0.368 0.000
R30-R39 Symptoms and signs involving the urinary system
0.632 0.368 0.000
Z44 Fitting and adjustment of external prosthetic device
0.631 0.369 0.000
H60-H62 Diseases of external ear
0.630 0.370 0.000
M45.X0 Ankylosing spondylitis (Multiple sites in spine)
0.630 0.370 0.000
D47.4 Osteomyelofibrosis
0.630 0.370 0.000
Z43.6 Attention to other artificial openings of urinary tract
0.630 0.370 0.000
M25.84 Other specified joint disorders (Hand)
0.629 0.371 0.000
I30.9 Acute pericarditis, unspecified
0.628 0.372 0.000
I05.9 Mitral valve disease, unspecified
0.628 0.372 0.000
D68 Other coagulation defects
0.628 0.372 0.000
R00.1 Bradycardia, unspecified
0.628 0.372 0.000
G93 Other disorders of brain
0.628 0.372 0.000
R27.0 Ataxia, unspecified
0.627 0.373 0.000
D61 Other aplastic anaemias
0.627 0.373 0.000
M94 Other disorders of cartilage
0.626 0.374 0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.626 0.374 0.000
E73 Lactose intolerance
0.626 0.374 0.000
M62 Other disorders of muscle
0.626 0.374 0.000
N94.3 Premenstrual tension syndrome
0.625 0.375 0.000
R78 Findings of drugs and other substances, not normally found in blood
0.625 0.375 0.000
R75 Laboratory evidence of human immunodeficiency virus [HIV]
0.625 0.375 0.000
R71 Abnormality of red blood cells
0.625 0.375 0.000
G00.9 Bacterial meningitis, unspecified
0.625 0.375 0.000
I51.6 Cardiovascular disease, unspecified
0.623 0.377 0.000
E22.1 Hyperprolactinaemia
0.621 0.379 0.000
E50-E64 Other nutritional deficiencies
0.621 0.379 0.000
I46 Cardiac arrest
0.621 0.379 0.000
N08 Glomerular disorders in diseases classified elsewhere
0.621 0.379 0.000
M24.86 Other specific joint derangements, not elsewhere classified (Lower leg)
0.620 0.380 0.000
G58 Other mononeuropathies
0.619 0.381 0.000
M21.6 Other acquired deformities of ankle and foot
0.618 0.382 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.618 0.382 0.000
F70-F79 Mental retardation
0.618 0.382 0.000
G04 Encephalitis, myelitis and encephalomyelitis
0.618 0.382 0.000
I51.5 Myocardial degeneration
0.617 0.383 0.000
I51.4 Myocarditis, unspecified
0.617 0.383 0.000
I51.2 Rupture of papillary muscle, not elsewhere classified
0.617 0.383 0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.617 0.383 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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