TreeWAS – Variant ID: rs560713

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
Z82.3 Family history of stroke	0.000	0.968	0.032
C80.0 Malignant neoplasm, primary site unknown, so stated	0.000	0.983	0.017
K11.2 Sialoadenitis	0.015	0.985	0.000
K11 Diseases of salivary glands	0.014	0.986	0.000
K11.6 Mucocele of salivary gland	0.014	0.986	0.000
C80 Malignant neoplasm without specification of site	0.000	0.987	0.013
C80.9 Malignant neoplasm, unspecified	0.000	0.987	0.013
D46.9 Myelodysplastic syndrome, unspecified	0.012	0.988	0.000
K11.7 Disturbances of salivary secretion	0.012	0.988	0.000
K11.5 Sialolithiasis	0.012	0.988	0.000
K11.1 Hypertrophy of salivary gland	0.011	0.989	0.000
K11.9 Disease of salivary gland, unspecified	0.011	0.989	0.000
D46 Myelodysplastic syndromes	0.011	0.989	0.000
K11.3 Abscess of salivary gland	0.011	0.989	0.000
K11.4 Fistula of salivary gland	0.010	0.990	0.000
K11.8 Other diseases of salivary glands	0.010	0.990	0.000
D46.2 Refractory anaemia with excess of blasts	0.010	0.990	0.000
K11.0 Atrophy of salivary gland	0.010	0.990	0.000
D46.4 Refractory anaemia, unspecified	0.009	0.991	0.000
D46.0 Refractory anaemia without sideroblasts, so stated	0.009	0.991	0.000
D46.7 Other myelodysplastic syndromes	0.009	0.991	0.000
D46.1 Refractory anaemia with sideroblasts	0.009	0.991	0.000
D46.6 Myelodysplastic syndrome with isolated del(5q) chromosomal abnormality	0.008	0.992	0.000
D46.3 Refractory anaemia with excess of blasts with transformation	0.008	0.992	0.000
D46.5 Refractory anaemia with multi-lineage dysplasia	0.008	0.992	0.000
C61 Malignant neoplasm of prostate	0.008	0.992	0.000
I69.3 Sequelae of cerebral infarction	0.000	0.993	0.007
T92.1 Sequelae of fracture of arm	0.000	0.994	0.006
L28.0 Lichen simplex chronicus	0.006	0.994	0.000
T92.9 Sequelae of unspecified injury of upper limb	0.000	0.995	0.005
S83.5 Sprain and strain involving (anterior)(posterior) cruciate ligament of knee	0.000	0.995	0.005
D04.6 Skin of upper limb, including shoulder	0.000	0.995	0.005
T92 Sequelae of injuries of upper limb	0.000	0.995	0.005
T92.2 Sequelae of fracture at wrist and hand level	0.000	0.995	0.005
R61.9 Hyperhidrosis, unspecified	0.005	0.995	0.000
M48.02 Spinal stenosis (Cervical region)	0.000	0.995	0.005
T92.8 Sequelae of other specified injuries of upper limb	0.000	0.996	0.004
T90 Sequelae of injuries of head	0.000	0.996	0.004
T90.5 Sequelae of intracranial injury	0.000	0.996	0.004
S83.2 Tear of meniscus, current	0.000	0.996	0.004
T90.2 Sequelae of fracture of skull and facial bones	0.000	0.996	0.004
K70.3 Alcoholic cirrhosis of liver	0.004	0.996	0.000
C60-C63 Malignant neoplasms of male genital organs	0.004	0.996	0.000
D04.3 Skin of other and unspecified parts of face	0.000	0.996	0.004
K58.9 Irritable bowel syndrome without diarrhoea	0.004	0.996	0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.000	0.996	0.004
C62 Malignant neoplasm of testis	0.004	0.996	0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee	0.000	0.996	0.004
T90.8 Sequelae of other specified injuries of head	0.000	0.996	0.004
D34 Benign neoplasm of thyroid gland	0.000	0.996	0.004
T91 Sequelae of injuries of neck and trunk	0.000	0.996	0.004
T90.0 Sequelae of superficial injury of head	0.000	0.996	0.003
M47.99 Spondylosis, unspecified (Site unspecified)	0.000	0.997	0.003
T92.4 Sequelae of injury of nerve of upper limb	0.000	0.997	0.003
C62.1 Descended testis	0.003	0.997	0.000
K80.1 Calculus of gallbladder with other cholecystitis	0.000	0.997	0.003
T90.3 Sequelae of injury of cranial nerves	0.000	0.997	0.003
Z82 Family history of certain disabilities and chronic diseases leading to disablement	0.000	0.997	0.003
T91.8 Sequelae of other specified injuries of neck and trunk	0.000	0.997	0.003
T90.1 Sequelae of open wound of head	0.000	0.997	0.003
T50.9 Other and unspecified drugs, medicaments and biological substances	0.003	0.997	0.000
K75.8 Other specified inflammatory liver diseases	0.000	0.997	0.003
T91.1 Sequelae of fracture of spine	0.000	0.997	0.003
S39.9 Unspecified injury of abdomen, lower back and pelvis	0.003	0.997	0.000
T92.0 Sequelae of open wound of upper limb	0.000	0.997	0.003
C63 Malignant neoplasm of other and unspecified male genital organs	0.003	0.997	0.000
S83.4 Sprain and strain involving (fibular)(tibial) collateral ligamnent of knee	0.000	0.997	0.003
T98 Sequelae of other and unspecified effects of external causes	0.000	0.997	0.003
C62.9 Testis, unspecified	0.003	0.997	0.000
Z82.5 Family history of asthma and other chronic lower respiratory diseases	0.000	0.997	0.003
S83.3 Tear of articular cartilage of knee, current	0.000	0.997	0.003
T95 Sequelae of burns, corrosions and frostbite	0.000	0.997	0.003
I08.3 Combined disorders of mitral, aortic and tricuspid valves	0.003	0.997	0.000
D04 Carcinoma in situ of skin	0.000	0.997	0.003
C77.0 Lymph nodes of head, face and neck	0.000	0.997	0.003
T92.6 Sequelae of crushing injury and traumatic amputation of upper limb	0.000	0.997	0.003
T91.3 Sequelae of injury of spinal cord	0.000	0.997	0.003
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source	0.000	0.997	0.003
T96 Sequelae of poisoning by drugs, medicaments and biological substances	0.000	0.997	0.003
C62.0 Undescended testis	0.003	0.997	0.000
T90.4 Sequelae of injury of eye and orbit	0.000	0.997	0.003
S83.0 Dislocation of patella	0.000	0.997	0.003
D04.7 Skin of lower limb, including hip	0.000	0.997	0.003
T91.5 Sequelae of injury of intra-abdominal and pelvic organs	0.000	0.997	0.003
T91.4 Sequelae of injury of intrathoracic organs	0.000	0.997	0.003
T91.2 Sequelae of other fracture of thorax and pelvis	0.000	0.997	0.003
T91.0 Sequelae of superficial injury and open wound of neck and trunk	0.000	0.997	0.003
K56.0 Paralytic ileus	0.000	0.997	0.003
F05.9 Delirium, unspecified	0.000	0.997	0.003
S02.10 Fracture of base of skull (closed)	0.000	0.997	0.003
T98.3 Sequelae of complications of surgical and medical care, not elsewhere classified	0.000	0.997	0.003
S81.9 Open wound of lower leg, part unspecified	0.000	0.997	0.003
S83.1 Dislocation of knee	0.000	0.997	0.002
S81.0 Open wound of knee	0.000	0.997	0.003
L28 Lichen simplex chronicus and prurigo	0.003	0.997	0.000
T92.5 Sequelae of injury of muscle and tendon of upper limb	0.000	0.997	0.002
T95.8 Sequelae of other specified burn, corrosion and frostbite	0.000	0.997	0.002
Z82.1 Family history of blindness and visual loss	0.000	0.997	0.002
I08.0 Disorders of both mitral and aortic valves	0.003	0.997	0.000
Z82.8 Family history of other disabilities and chronic diseases leading to disablement, not elsewhere classified	0.000	0.997	0.002
Z82.6 Family history of arthritis and other diseases of the musculoskeletal system and connective tissue	0.000	0.997	0.003
Z82.2 Family history of deafness and hearing loss	0.000	0.997	0.002
C63.2 Scrotum	0.002	0.997	0.000
T90.9 Sequelae of unspecified injury of head	0.000	0.997	0.002
C60 Malignant neoplasm of penis	0.002	0.997	0.000
Y86 Sequelae of other accidents	0.000	0.997	0.002
C63.9 Male genital organ, unspecified	0.002	0.998	0.000
C63.8 Overlapping lesion of male genital organs	0.002	0.998	0.000
C63.7 Other specified male genital organs	0.002	0.998	0.000
C63.1 Spermatic cord	0.002	0.998	0.000
C63.0 Epididymis	0.002	0.998	0.000
T95.2 Sequelae of burn, corrosion and frostbite of upper limb	0.000	0.998	0.002
T98.2 Sequelae of certain early complications of trauma	0.000	0.998	0.002
T98.0 Sequelae of effects of foreign body entering through natural orifice	0.000	0.998	0.002
M80.00 Postmenopausal osteoporosis with pathological fracture (Multiple sites)	0.000	0.998	0.002
G81.1 Spastic hemiplegia	0.000	0.998	0.002
S81 Open wound of lower leg	0.000	0.998	0.002
T92.3 Sequelae of dislocation, sprain and strain of upper limb	0.000	0.998	0.002
T95.3 Sequelae of burn, corrosion and frostbite of lower limb	0.000	0.998	0.002
S83.7 Injury to multiple structures of knee	0.000	0.998	0.002
T95.9 Sequelae of unspecified burn, corrosion and frostbite	0.000	0.998	0.002
T95.4 Sequelae of burn and corrosion classifiable only according to extent of body surface involved	0.000	0.998	0.002
T98.1 Sequelae of other and unspecified effects of external causes	0.000	0.998	0.002
T94 Sequelae of injuries involving multiple and unspecified body regions	0.000	0.998	0.002
D04.8 Skin of other sites	0.000	0.998	0.002
D04.0 Skin of lip	0.000	0.998	0.002
T91.9 Sequelae of unspecified injury of neck and trunk	0.000	0.998	0.002
I80.0 Phlebitis and thrombophlebitis of superficial vessels of lower extremities	0.000	0.998	0.002
T95.1 Sequelae of burn, corrosion and frostbite of trunk	0.000	0.998	0.002
U51.1 Previously admitted to a psychiatric hospital of the provider	0.002	0.998	0.000
S83.6 Sprain and strain of other and unspecified parts of knee	0.000	0.998	0.002
T40.4 Other synthetic narcotics	0.000	0.998	0.002
L05.0 Pilonidal cyst with abscess	0.002	0.998	0.000
T95.0 Sequelae of burn, corrosion and frostbite of head and neck	0.000	0.998	0.002
S72.20 Subtrochanteric fracture (closed)	0.002	0.998	0.000
T23.3 Burn of third degree of wrist and hand	0.000	0.998	0.002
L28.1 Prurigo nodularis	0.002	0.998	0.000
Z82.7 Family history of congenital malformations, deformations and chromosomal abnormalities	0.000	0.998	0.002
D04.1 Skin of eyelid, including canthus	0.000	0.998	0.002
S81.8 Open wound of other parts of lower leg	0.000	0.998	0.002
T93.8 Sequelae of other specified injuries of lower limb	0.000	0.998	0.002
Z57.5 Occupational exposure to toxic agents in other industries	0.000	0.998	0.002
I80.1 Phlebitis and thrombophlebitis of femoral vein	0.000	0.998	0.002
S02.1 Fracture of base of skull	0.000	0.998	0.002
Z99.2 Dependence on renal dialysis	0.000	0.998	0.002
M80.10 Postoophorectomy osteoporosis with pathological fracture (Multiple sites)	0.000	0.998	0.002
D04.9 Skin, unspecified	0.000	0.998	0.002
L28.2 Other prurigo	0.002	0.998	0.000
M21.07 Valgus deformity, not elsewhere classified (Ankle and foot)	0.000	0.998	0.002
C60.0 Prepuce	0.002	0.998	0.000
D04.4 Skin of scalp and neck	0.000	0.998	0.002
C60.8 Overlapping lesion of penis	0.002	0.998	0.000
C60.2 Body of penis	0.002	0.998	0.000
T94.0 Sequelae of injuries involving multiple body regions	0.000	0.998	0.002
Y87.0 Sequelae of intentional self-harm	0.000	0.998	0.002
S02.80 Fractures of other skull and facial bones (closed)	0.000	0.998	0.002
I95.9 Hypotension, unspecified	0.002	0.998	0.000
I08 Multiple valve diseases	0.002	0.998	0.000
S02.11 Fracture of base of skull (open)	0.000	0.998	0.002
I07.1 Tricuspid insufficiency	0.002	0.998	0.000
R61 Hyperhidrosis	0.002	0.998	0.000
B18.2 Chronic viral hepatitis C	0.002	0.998	0.000
D04.2 Skin of ear and external auricular canal	0.000	0.998	0.002
M80.0 Postmenopausal osteoporosis with pathological fracture	0.000	0.998	0.002
S89.8 Other specified injuries of lower leg	0.000	0.998	0.002
Z82.0 Family history of epilepsy and other diseases of the nervous system	0.000	0.998	0.002
Y87.1 Sequelae of assault	0.000	0.998	0.002
T50.6 Antidotes and chelating agents, not elsewhere classified	0.002	0.998	0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.002	0.998	0.000
T23.2 Burn of second degree of wrist and hand	0.000	0.998	0.002
S32.00 Fracture of lumbar vertebra (closed)	0.002	0.998	0.000
F25.1 Schizoaffective disorder, depressive type	0.002	0.998	0.000
I08.9 Multiple valve disease, unspecified	0.002	0.998	0.000
G81 Hemiplegia	0.000	0.998	0.002
I69 Sequelae of cerebrovascular disease	0.000	0.998	0.002
Y87 Sequelae of intentional self-harm, assault and events of undetermined intent	0.000	0.998	0.002
F25.9 Schizoaffective disorder, unspecified	0.002	0.998	0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis	0.002	0.998	0.000
C60.1 Glans penis	0.001	0.998	0.000
O70.2 Third degree perineal laceration during delivery	0.000	0.998	0.002
S81.7 Multiple open wounds of lower leg	0.000	0.998	0.002
M80.1 Postoophorectomy osteoporosis with pathological fracture	0.000	0.998	0.002
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.002	0.998	0.000
F03 Unspecified dementia	0.002	0.998	0.000
K35.1 Acute appendicitis with peritoneal abscess	0.000	0.998	0.002
S19.9 Unspecified injury of neck	0.002	0.998	0.000
F25 Schizoaffective disorders	0.002	0.998	0.000
S72.10 Pertrochanteric fracture (closed)	0.002	0.998	0.000
B35.3 Tinea pedis	0.002	0.998	0.000
G80.1 Spastic diplegia	0.000	0.998	0.002
M80.99 Unspecified osteoporosis with pathological fracture (Site unspecified)	0.000	0.998	0.002
Q44.5 Other congenital malformations of bile ducts	0.002	0.998	0.000
M80.90 Unspecified osteoporosis with pathological fracture (Multiple sites)	0.000	0.998	0.002
C60.9 Penis, unspecified	0.001	0.998	0.000
G80.9 Infantile cerebral palsy, unspecified	0.000	0.998	0.002
G80 Infantile cerebral palsy	0.000	0.998	0.002
S02.8 Fractures of other skull and facial bones	0.000	0.998	0.002
M25.36 Other instability of joint (Lower leg)	0.000	0.998	0.002
I69.1 Sequelae of intracerebral haemorrhage	0.000	0.998	0.002
G31.2 Degeneration of nervous system due to alcohol	0.002	0.998	0.000
R61.0 Localised hyperhidrosis	0.002	0.998	0.000
K58 Irritable bowel syndrome	0.002	0.998	0.000
M80.09 Postmenopausal osteoporosis with pathological fracture (Site unspecified)	0.000	0.998	0.002
M80.08 Postmenopausal osteoporosis with pathological fracture (Other)	0.000	0.998	0.002
M80.07 Postmenopausal osteoporosis with pathological fracture (Ankle and foot)	0.000	0.998	0.002
M80.06 Postmenopausal osteoporosis with pathological fracture (Lower leg)	0.000	0.998	0.002
M80.05 Postmenopausal osteoporosis with pathological fracture (Pelvic region and thigh)	0.000	0.998	0.002
M80.04 Postmenopausal osteoporosis with pathological fracture (Hand)	0.000	0.998	0.002
M80.03 Postmenopausal osteoporosis with pathological fracture (Forearm)	0.000	0.998	0.002
M80.02 Postmenopausal osteoporosis with pathological fracture (Upper arm)	0.000	0.998	0.002
M80.01 Postmenopausal osteoporosis with pathological fracture (Shoulder region)	0.000	0.998	0.002
S72.2 Subtrochanteric fracture	0.002	0.998	0.000
S89 Other and unspecified injuries of lower leg	0.000	0.998	0.002
S30.2 Contusion of external genital organs	0.002	0.998	0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.002	0.998	0.000
M79.69 Pain in limb (Site unspecified)	0.000	0.998	0.002
I69.8 Sequelae of other and unspecified cerebrovascular diseases	0.000	0.998	0.002
T50.7 Analeptics and opioid receptor antagonists	0.002	0.998	0.000
T50.5 Appetite depressants	0.002	0.998	0.000
T50.3 Electrolytic, caloric and water-balance agents	0.002	0.998	0.000
T50.1 Loop [high-ceiling] diuretics	0.002	0.998	0.000
T50.0 Mineralocorticoids and their antagonists	0.002	0.998	0.000
Z50.8 Care involving use of rehabilitation procedures	0.000	0.998	0.002
F25.0 Schizoaffective disorder, manic type	0.002	0.998	0.000
G80.0 Spastic cerebral palsy	0.000	0.998	0.002
G82.1 Spastic paraplegia	0.000	0.998	0.002
I08.2 Disorders of both aortic and tricuspid valves	0.002	0.998	0.000
Q38.7 Pharyngeal pouch	0.002	0.998	0.000
R61.1 Generalised hyperhidrosis	0.001	0.998	0.000
T50.4 Drugs affecting uric acid metabolism	0.002	0.998	0.000
F29 Unspecified nonorganic psychosis	0.002	0.998	0.000
D04.5 Skin of trunk	0.000	0.998	0.001
Q44.4 Choledochal cyst	0.002	0.998	0.000
S32.0 Fracture of lumbar vertebra	0.002	0.998	0.000
G81.0 Flaccid hemiplegia	0.000	0.998	0.001
S39.7 Other multiple injuries of abdomen, lower back and pelvis	0.001	0.998	0.000
S39.6 Injury of intra-abdominal organ(s) with pelvic organ(s)	0.001	0.998	0.000
M80.19 Postoophorectomy osteoporosis with pathological fracture (Site unspecified)	0.000	0.998	0.001
M80.18 Postoophorectomy osteoporosis with pathological fracture (Other)	0.000	0.998	0.001
M80.17 Postoophorectomy osteoporosis with pathological fracture (Ankle and foot)	0.000	0.998	0.001
M80.16 Postoophorectomy osteoporosis with pathological fracture (Lower leg)	0.000	0.998	0.001
M80.15 Postoophorectomy osteoporosis with pathological fracture (Pelvic region and thigh)	0.000	0.998	0.001
M80.14 Postoophorectomy osteoporosis with pathological fracture (Hand)	0.000	0.998	0.001
M80.13 Postoophorectomy osteoporosis with pathological fracture (Forearm)	0.000	0.998	0.001
M80.12 Postoophorectomy osteoporosis with pathological fracture (Upper arm)	0.000	0.998	0.001
M80.11 Postoophorectomy osteoporosis with pathological fracture (Shoulder region)	0.000	0.998	0.001
M80.9 Unspecified osteoporosis with pathological fracture	0.000	0.998	0.002
S02.4 Fracture of malar and maxillary bones	0.000	0.998	0.002
Y83.8 Other surgical procedures	0.000	0.998	0.002
F25.8 Other schizoaffective disorders	0.001	0.998	0.000
G80.8 Other infantile cerebral palsy	0.000	0.998	0.001
H06.2 Dysthyroid exophthalmos	0.000	0.998	0.002
T50.8 Diagnostic agents	0.001	0.998	0.000
Q44 Congenital malformations of gallbladder, bile ducts and liver	0.002	0.998	0.000
S02.40 Fracture of malar and maxillary bones (closed)	0.000	0.998	0.002
I69.2 Sequelae of other nontraumatic intracranial haemorrhage	0.000	0.998	0.001
Q44.7 Other congenital malformations of liver	0.001	0.998	0.000
Z87.4 Personal history of diseases of the genito-urinary system	0.000	0.998	0.002
I07 Rheumatic tricuspid valve diseases	0.002	0.998	0.000
M80 Osteoporosis with pathological fracture	0.000	0.998	0.002
I98.2 Oesophageal varices in diseases classified elsewhere	0.002	0.998	0.000
T23 Burn and corrosion of wrist and hand	0.000	0.998	0.002
S02.41 Fracture of malar and maxillary bones (open)	0.000	0.998	0.001
S02.81 Fractures of other skull and facial bones (open)	0.000	0.998	0.001
S32.80 Fracture of other and unspecified parts of lumbar spine and pelvis (closed)	0.001	0.998	0.000
G80.4 Ataxic cerebral palsy	0.000	0.998	0.001
G80.3 Dyskinetic cerebral palsy	0.000	0.998	0.001
K63.8 Other specified diseases of intestine	0.002	0.998	0.000
Y42.7 Androgens and anabolic congeners	0.000	0.998	0.002
T93 Sequelae of injuries of lower limb	0.000	0.998	0.002
M13.09 Polyarthritis, unspecified (Site unspecified)	0.001	0.998	0.000
G81.9 Hemiplegia, unspecified	0.000	0.998	0.002
Y87.2 Sequelae of events of undetermined intent	0.000	0.998	0.001
S02 Fracture of skull and facial bones	0.000	0.998	0.002
S72.21 Subtrochanteric fracture (open)	0.001	0.998	0.000
F25.2 Schizoaffective disorder, mixed type	0.001	0.998	0.000
G11.9 Hereditary ataxia, unspecified	0.001	0.998	0.000
S72.1 Pertrochanteric fracture	0.001	0.998	0.000
S89.7 Multiple injuries of lower leg	0.000	0.998	0.001
S89.1 Other specified injuries of lower leg	0.000	0.998	0.001
S89.0 Multiple injuries of lower leg	0.000	0.998	0.001
T94.1 Sequelae of injuries, not specified by body region	0.000	0.998	0.001
F20.0 Paranoid schizophrenia	0.001	0.999	0.000
K22.5 Diverticulum of oesophagus, acquired	0.001	0.999	0.000
S02.0 Fracture of vault of skull	0.000	0.999	0.001
M46.92 Inflammatory spondylopathy, unspecified (Cervical region)	0.000	0.999	0.001
S89.9 Unspecified injury of lower leg	0.000	0.999	0.001
O00.9 Ectopic pregnancy, unspecified	0.001	0.999	0.000
S32.8 Fracture of other and unspecified parts of lumbar spine and pelvis	0.001	0.999	0.000
S39.8 Other specified injuries of abdomen, lower back and pelvis	0.001	0.999	0.000
T78.3 Angioneurotic oedema	0.001	0.999	0.000
X51.9 Unspecified place	0.001	0.999	0.000
G82 Paraplegia and tetraplegia	0.000	0.999	0.001
S80-S89 Injuries to the knee and lower leg	0.000	0.999	0.001
S32.01 Fracture of lumbar vertebra (open)	0.001	0.999	0.000
G80.2 Infantile hemiplegia	0.000	0.999	0.001
K58.0 Irritable bowel syndrome with diarrhoea	0.001	0.999	0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality	0.000	0.999	0.001
M80.97 Unspecified osteoporosis with pathological fracture (Ankle and foot)	0.000	0.999	0.001
M80.96 Unspecified osteoporosis with pathological fracture (Lower leg)	0.000	0.999	0.001
M80.94 Unspecified osteoporosis with pathological fracture (Hand)	0.000	0.999	0.001
M80.93 Unspecified osteoporosis with pathological fracture (Forearm)	0.000	0.999	0.001
M80.92 Unspecified osteoporosis with pathological fracture (Upper arm)	0.000	0.999	0.001
M80.91 Unspecified osteoporosis with pathological fracture (Shoulder region)	0.000	0.999	0.001
S02.00 Fracture of vault of skull (closed)	0.000	0.999	0.001
S32.30 Fracture of ilium (closed)	0.001	0.999	0.000
Q44.6 Cystic disease of liver	0.001	0.999	0.000
Q87.8 Other specified congenital malformation syndromes, not elsewhere classified	0.000	0.999	0.001
G31.8 Other specified degenerative diseases of nervous system	0.001	0.999	0.000
G82.4 Spastic tetraplegia	0.000	0.999	0.001
M80.4 Drug-induced osteoporosis with pathological fracture	0.000	0.999	0.001
M80.3 Postsurgical malabsorption osteoporosis with pathological fracture	0.000	0.999	0.001
M80.2 Osteoporosis of disuse with pathological fracture	0.000	0.999	0.001
Q44.3 Congenital stenosis and stricture of bile ducts	0.001	0.999	0.000
Q44.2 Atresia of bile ducts	0.001	0.999	0.000
Q44.1 Other congenital malformations of gallbladder	0.001	0.999	0.000
Q44.0 Agenesis, aplasia and hypoplasia of gallbladder	0.001	0.999	0.000
S02.7 Multiple fractures involving skull and facial bones	0.000	0.999	0.001
S32.3 Fracture of ilium	0.001	0.999	0.000
S39.0 Injury of muscle and tendon of abdomen, lower back and pelvis	0.001	0.999	0.000
S02.01 Fracture of vault of skull (open)	0.000	0.999	0.001
I07.9 Tricuspid valve disease, unspecified	0.001	0.999	0.000
I07.8 Other tricuspid valve diseases	0.001	0.999	0.000
I07.2 Tricuspid stenosis with insufficiency	0.001	0.999	0.000
I07.0 Tricuspid stenosis	0.001	0.999	0.000
M80.5 Idiopathic osteoporosis with pathological fracture	0.000	0.999	0.001
T23.7 Corrosion of third degree of wrist and hand	0.000	0.999	0.001
T23.6 Corrosion of second degree of wrist and hand	0.000	0.999	0.001
T23.5 Corrosion of first degree of wrist and hand	0.000	0.999	0.001
T23.4 Corrosion of unspecified degree of wrist and hand	0.000	0.999	0.001
X51.8 Other specified place	0.001	0.999	0.000
S32 Fracture of lumbar spine and pelvis	0.001	0.999	0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.001	0.999	0.000
M80.95 Unspecified osteoporosis with pathological fracture (Pelvic region and thigh)	0.000	0.999	0.001
S02.6 Fracture of mandible	0.000	0.999	0.001
T93.4 Sequelae of injury of nerve of lower limb	0.000	0.999	0.001
G80-G83 Cerebral palsy and other paralytic syndromes	0.000	0.999	0.001
S72.11 Pertrochanteric fracture (open)	0.001	0.999	0.000
B97.8 Other viral agents as the cause of diseases classified to other chapters	0.000	0.999	0.001
F20.5 Residual schizophrenia	0.001	0.999	0.000
I80.8 Phlebitis and thrombophlebitis of other sites	0.000	0.999	0.001
R22.9 Localised swelling, mass and lump, unspecified	0.000	0.999	0.001
G91.1 Obstructive hydrocephalus	0.000	0.999	0.001
X50.4 Street and highway	0.001	0.999	0.000
Y45.1 Salicylates	0.000	0.999	0.001
F20 Schizophrenia	0.001	0.999	0.000
S85 Injury of blood vessels at lower leg level	0.000	0.999	0.001
S02.70 Multiple fractures involving skull and facial bones (closed)	0.000	0.999	0.001
S32.81 Fracture of other and unspecified parts of lumbar spine and pelvis (open)	0.001	0.999	0.000
H18.6 Keratoconus	0.000	0.999	0.001
S02.3 Fracture of orbital floor	0.000	0.999	0.001
S32.1 Fracture of sacrum	0.001	0.999	0.000
S71.1 Open wound of thigh	0.001	0.999	0.000
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis	0.001	0.999	0.000
S88 Traumatic amputation of lower leg	0.000	0.999	0.001
C43.3 Malignant melanoma of other and unspecified parts of face	0.001	0.999	0.000
G82.3 Flaccid tetraplegia	0.000	0.999	0.001
G82.0 Flaccid paraplegia	0.000	0.999	0.001
T93.6 Sequelae of crushing injury and traumatic amputation of lower limb	0.000	0.999	0.001
X50.2 School, other institution and public administrative area	0.001	0.999	0.000
X51 Travel and motion	0.001	0.999	0.000
K05.3 Chronic periodontitis	0.001	0.999	0.000
O04.1 Incomplete, complicated by delayed or excessive haemorrhage	0.000	0.999	0.001
S33.5 Sprain and strain of lumbar spine	0.001	0.999	0.000
T23.1 Burn of first degree of wrist and hand	0.000	0.999	0.001
T93.5 Sequelae of injury of muscle and tendon of lower limb	0.000	0.999	0.001
F21 Schizotypal disorder	0.001	0.999	0.000
M25.99 Joint disorder, unspecified (Site unspecified)	0.001	0.999	0.000
M80.29 Osteoporosis of disuse with pathological fracture (Site unspecified)	0.000	0.999	0.001
M80.28 Osteoporosis of disuse with pathological fracture (Other)	0.000	0.999	0.001
M80.27 Osteoporosis of disuse with pathological fracture (Ankle and foot)	0.000	0.999	0.001
M80.26 Osteoporosis of disuse with pathological fracture (Lower leg)	0.000	0.999	0.001
M80.25 Osteoporosis of disuse with pathological fracture (Pelvic region and thigh)	0.000	0.999	0.001
M80.24 Osteoporosis of disuse with pathological fracture (Hand)	0.000	0.999	0.001
M80.23 Osteoporosis of disuse with pathological fracture (Forearm)	0.000	0.999	0.001
M80.22 Osteoporosis of disuse with pathological fracture (Upper arm)	0.000	0.999	0.001
M80.21 Osteoporosis of disuse with pathological fracture (Shoulder region)	0.000	0.999	0.001
M80.20 Osteoporosis of disuse with pathological fracture (Multiple sites)	0.000	0.999	0.001
M80.39 Postsurgical malabsorption osteoporosis with pathological fracture (Site unspecified)	0.000	0.999	0.001
M80.38 Postsurgical malabsorption osteoporosis with pathological fracture (Other)	0.000	0.999	0.001
M80.37 Postsurgical malabsorption osteoporosis with pathological fracture (Ankle and foot)	0.000	0.999	0.001
M80.36 Postsurgical malabsorption osteoporosis with pathological fracture (Lower leg)	0.000	0.999	0.001
M80.35 Postsurgical malabsorption osteoporosis with pathological fracture (Pelvic region and thigh)	0.000	0.999	0.001
M80.34 Postsurgical malabsorption osteoporosis with pathological fracture (Hand)	0.000	0.999	0.001
M80.33 Postsurgical malabsorption osteoporosis with pathological fracture (Forearm)	0.000	0.999	0.001
M80.32 Postsurgical malabsorption osteoporosis with pathological fracture (Upper arm)	0.000	0.999	0.001
M80.31 Postsurgical malabsorption osteoporosis with pathological fracture (Shoulder region)	0.000	0.999	0.001
M80.30 Postsurgical malabsorption osteoporosis with pathological fracture (Multiple sites)	0.000	0.999	0.001
M80.49 Drug-induced osteoporosis with pathological fracture (Site unspecified)	0.000	0.999	0.001
M80.48 Drug-induced osteoporosis with pathological fracture (Other)	0.000	0.999	0.001
M80.47 Drug-induced osteoporosis with pathological fracture (Ankle and foot)	0.000	0.999	0.001
M80.46 Drug-induced osteoporosis with pathological fracture (Lower leg)	0.000	0.999	0.001
M80.45 Drug-induced osteoporosis with pathological fracture (Pelvic region and thigh)	0.000	0.999	0.001
M80.44 Drug-induced osteoporosis with pathological fracture (Hand)	0.000	0.999	0.001
M80.43 Drug-induced osteoporosis with pathological fracture (Forearm)	0.000	0.999	0.001
M80.42 Drug-induced osteoporosis with pathological fracture (Upper arm)	0.000	0.999	0.001
M80.41 Drug-induced osteoporosis with pathological fracture (Shoulder region)	0.000	0.999	0.001
M80.40 Drug-induced osteoporosis with pathological fracture (Multiple sites)	0.000	0.999	0.001
M80.50 Idiopathic osteoporosis with pathological fracture (Multiple sites)	0.000	0.999	0.001
S02.71 Multiple fractures involving skull and facial bones (open)	0.000	0.999	0.001
S32.31 Fracture of ilium (open)	0.001	0.999	0.000
D69.5 Secondary thrombocytopenia	0.000	0.999	0.001
F79.9 Unspecified mental retardation (Without mention of impairment of behaviour)	0.001	0.999	0.000
L05.9 Pilonidal cyst without abscess	0.001	0.999	0.000
M80.8 Other osteoporosis with pathological fracture	0.000	0.999	0.001
S33.1 Dislocation of lumbar vertebra	0.001	0.999	0.000
S34.1 Other injury of lumbar spinal cord	0.001	0.999	0.000
F28 Other nonorganic psychotic disorders	0.001	0.999	0.000
F24 Induced delusional disorder	0.001	0.999	0.000
S37 Injury of urinary and pelvic organs	0.001	0.999	0.000
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level	0.001	0.999	0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.001	0.999	0.000
M25.95 Joint disorder, unspecified (Pelvic region and thigh)	0.001	0.999	0.000
M80.59 Idiopathic osteoporosis with pathological fracture (Site unspecified)	0.000	0.999	0.001
M80.58 Idiopathic osteoporosis with pathological fracture (Other)	0.000	0.999	0.001
M80.57 Idiopathic osteoporosis with pathological fracture (Ankle and foot)	0.000	0.999	0.001
M80.56 Idiopathic osteoporosis with pathological fracture (Lower leg)	0.000	0.999	0.001
M80.55 Idiopathic osteoporosis with pathological fracture (Pelvic region and thigh)	0.000	0.999	0.001
M80.54 Idiopathic osteoporosis with pathological fracture (Hand)	0.000	0.999	0.001
M80.53 Idiopathic osteoporosis with pathological fracture (Forearm)	0.000	0.999	0.001
M80.51 Idiopathic osteoporosis with pathological fracture (Shoulder region)	0.000	0.999	0.001
S02.61 Fracture of mandible (open)	0.000	0.999	0.001
S32.10 Fracture of sacrum (closed)	0.001	0.999	0.000
S72.70 Multiple fractures of femur (closed)	0.001	0.999	0.000
G31.0 Circumscribed brain atrophy	0.001	0.999	0.000
I69.0 Sequelae of subarachnoid haemorrhage	0.000	0.999	0.001
K35.8 Acute appendicitis, other and unspecified	0.000	0.999	0.001
R06.8 Other and unspecified abnormalities of breathing	0.000	0.999	0.001
S32.4 Fracture of acetabulum	0.001	0.999	0.000
S32.2 Fracture of coccyx	0.001	0.999	0.000
S33.2 Dislocation of sacro-iliac and sacrococcygeal joint	0.001	0.999	0.000
S85.1 Injury of (anterior)(posterior) tibial artery	0.000	0.999	0.001
X50.6 Industrial and construction area	0.001	0.999	0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified	0.001	0.999	0.000
L05 Pilonidal cyst	0.001	0.999	0.000
X50 Overexertion and strenuous or repetitive movements	0.001	0.999	0.000
M25.97 Joint disorder, unspecified (Ankle and foot)	0.001	0.999	0.000
S37.20 Injury of bladder (without open wound into cavity)	0.001	0.999	0.000
D17.9 Benign lipomatous neoplasm, unspecified	0.001	0.999	0.000
F20.6 Simple schizophrenia	0.001	0.999	0.000
F20.4 Postschizophrenic depression	0.001	0.999	0.000
F20.3 Undifferentiated schizophrenia	0.001	0.999	0.000
F20.1 Hebephrenic schizophrenia	0.001	0.999	0.000
F22.9 Persistent delusional disorder, unspecified	0.001	0.999	0.000
I36.1 Nonrheumatic tricuspid (valve) insufficiency	0.001	0.999	0.000
S37.2 Injury of bladder	0.001	0.999	0.000
S72.7 Multiple fractures of femur	0.001	0.999	0.000
S87 Crushing injury of lower leg	0.000	0.999	0.001
S84 Injury of nerves at lower leg level	0.000	0.999	0.001
M81.40 Drug-induced osteoporosis (Multiple sites)	0.000	0.999	0.001
S02.60 Fracture of mandible (closed)	0.000	0.999	0.001
S32.11 Fracture of sacrum (open)	0.001	0.999	0.000
D68.0 Von Willebrand's disease	0.001	0.999	0.000
G82.5 Tetraplegia, unspecified	0.000	0.999	0.001
Q85.0 Neurofibromatosis (nonmalignant)	0.000	0.999	0.001
S02.9 Fracture of skull and facial bones, part unspecified	0.000	0.999	0.001
S33.7 Sprain and strain of other and unspecified parts of lumbar spine and pelvis	0.001	0.999	0.000
S33.6 Sprain and strain of sacro-iliac joint	0.001	0.999	0.000
S33.4 Traumatic rupture of symphysis pubis	0.001	0.999	0.000
S33.3 Dislocation of other and unspecified parts of lumbar spine and pelvis	0.001	0.999	0.000
S33.0 Traumatic rupture of lumbar intervertebral disk	0.001	0.999	0.000
S85.9 Injury of unspecified blood vessel at lower leg level	0.000	0.999	0.001
S85.8 Injury of other blood vessels at lower leg level	0.000	0.999	0.001
S85.7 Injury of multiple blood vessels at lower leg level	0.000	0.999	0.001
S85.5 Injury of popliteal vein	0.000	0.999	0.001
S85.4 Injury of lesser saphenous vein at lower leg level	0.000	0.999	0.001
S85.3 Injury of greater saphenous vein at lower leg level	0.000	0.999	0.001
S85.2 Injury of peroneal artery	0.000	0.999	0.001
S85.0 Injury of popliteal artery	0.000	0.999	0.001
X51.1 Residential institution	0.001	0.999	0.000
S72 Fracture of femur	0.001	0.999	0.000
S02.31 Fracture of orbital floor (open)	0.000	0.999	0.001
E13.9 Without complications	0.000	0.999	0.001
I08.8 Other multiple valve diseases	0.001	0.999	0.000
K02.8 Other dental caries	0.000	0.999	0.001
Q39.6 Diverticulum of oesophagus	0.001	0.999	0.000
S72.3 Fracture of shaft of femur	0.001	0.999	0.000
S88.9 Traumatic amputation of lower leg, level unspecified	0.000	0.999	0.001
S88.1 Traumatic amputation at level between knee and ankle	0.000	0.999	0.001
S88.0 Traumatic amputation at knee level	0.000	0.999	0.001
T14.0 Superficial injury of unspecified body region	0.001	0.999	0.000
T23.0 Burn of unspecified degree of wrist and hand	0.000	0.999	0.001
T75.4 Effects of electric current	0.001	0.999	0.000
T93.9 Sequelae of unspecified injury of lower limb	0.000	0.999	0.001
X51.7 Farm	0.001	0.999	0.000
X51.6 Industrial and construction area	0.001	0.999	0.000
X51.5 Trade and service area	0.001	0.999	0.000
X51.4 Street and highway	0.001	0.999	0.000
X51.3 Sports and athletics area	0.001	0.999	0.000
X51.2 School, other institution and public administrative area	0.001	0.999	0.000
X51.0 Home	0.001	0.999	0.000
M80.52 Idiopathic osteoporosis with pathological fracture (Upper arm)	0.000	0.999	0.001
M80.89 Other osteoporosis with pathological fracture (Site unspecified)	0.000	0.999	0.001
M80.87 Other osteoporosis with pathological fracture (Ankle and foot)	0.000	0.999	0.001
M80.86 Other osteoporosis with pathological fracture (Lower leg)	0.000	0.999	0.001
M80.85 Other osteoporosis with pathological fracture (Pelvic region and thigh)	0.000	0.999	0.001
M80.84 Other osteoporosis with pathological fracture (Hand)	0.000	0.999	0.001
M80.83 Other osteoporosis with pathological fracture (Forearm)	0.000	0.999	0.001
M80.82 Other osteoporosis with pathological fracture (Upper arm)	0.000	0.999	0.001
M80.80 Other osteoporosis with pathological fracture (Multiple sites)	0.000	0.999	0.001

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations