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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs56890907
log Bayes Factor = 17.4615
Chromosome 3   position 196,673,831  (GRCh37) Explore rs56890907 on Ensembl!
Variant rs56890907 is part of Cluster X0142

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
I30-I52 Other forms of heart disease
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
Chapter XIV Diseases of the genitourinary system
1.000 0.000 0.000
E10-E14 Diabetes mellitus
0.999 0.001 0.000
E10 Insulin-dependent diabetes mellitus
0.998 0.002 0.000
I20-I25 Ischaemic heart diseases
0.996 0.004 0.000
I25 Chronic ischaemic heart disease
0.996 0.004 0.000
I44 Atrioventricular and left bundle-branch block
0.995 0.005 0.000
N17-N19 Renal failure
0.995 0.005 0.000
I50 Heart failure
0.993 0.007 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.992 0.008 0.000
N18 Chronic renal failure
0.989 0.011 0.000
I50.1 Left ventricular failure
0.984 0.016 0.000
I25.2 Old myocardial infarction
0.980 0.020 0.000
Chapter I Certain infectious and parasitic diseases
0.980 0.020 0.000
Chapter XX External causes of morbidity and mortality
0.980 0.020 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.979 0.021 0.000
I34 Nonrheumatic mitral valve disorders
0.975 0.025 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.975 0.025 0.000
I44.0 Atrioventricular block, first degree
0.970 0.030 0.000
B95-B98 Bacterial, viral and other infectious agents
0.966 0.034 0.000
I35 Nonrheumatic aortic valve disorders
0.963 0.037 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.961 0.039 0.000
I05-I09 Chronic rheumatic heart diseases
0.954 0.046 0.000
N10-N16 Renal tubulo-interstitial diseases
0.952 0.048 0.000
I34.0 Mitral (valve) insufficiency
0.950 0.050 0.000
N18.9 Chronic renal failure, unspecified
0.945 0.055 0.000
E70-E90 Metabolic disorders
0.944 0.056 0.000
E10.9 Without complications
0.936 0.064 0.000
I44.7 Left bundle-branch block, unspecified
0.935 0.065 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.934 0.066 0.000
I60-I69 Cerebrovascular diseases
0.933 0.067 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.931 0.069 0.000
E10.1 With ketoacidosis
0.926 0.074 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.926 0.074 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.919 0.081 0.000
I31 Other diseases of pericardium
0.919 0.081 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.916 0.084 0.000
Chapter VI Diseases of the nervous system
0.916 0.084 0.000
I35.0 Aortic (valve) stenosis
0.914 0.086 0.000
O80-O84 Delivery
0.913 0.087 0.000
N20-N23 Urolithiasis
0.904 0.096 0.000
N18.3 Chronic kidney disease, stage 3
0.903 0.097 0.000
Chapter II Neoplasms
0.901 0.099 0.000
S60-S69 Injuries to the wrist and hand
0.901 0.099 0.000
E10.5 With peripheral circulatory complications
0.897 0.103 0.000
T66-T78 Other and unspecified effects of external causes
0.893 0.107 0.000
N75 Diseases of Bartholin's gland
0.889 0.111 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.889 0.111 0.000
E14 Unspecified diabetes mellitus
0.888 0.112 0.000
D80-D89 Certain disorders involving the immune mechanism
0.887 0.113 0.000
I73 Other peripheral vascular diseases
0.885 0.115 0.000
V20-V29 Motorcycle rider injured in transport accident
0.883 0.117 0.000
I22 Subsequent myocardial infarction
0.882 0.118 0.000
E20-E35 Disorders of other endocrine glands
0.881 0.119 0.000
C15-C26 Malignant neoplasms of digestive organs
0.878 0.122 0.000
I95 Hypotension
0.877 0.123 0.000
E10.3 With ophthalmic complications
0.877 0.123 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.875 0.125 0.000
N17 Acute renal failure
0.875 0.125 0.000
B95.6 Staphylococcus aureus as the cause of diseases classified to other chapters
0.873 0.127 0.000
I50.9 Heart failure, unspecified
0.873 0.127 0.000
I08 Multiple valve diseases
0.871 0.129 0.000
I51 Complications and ill-defined descriptions of heart disease
0.870 0.130 0.000
N18.4 Chronic kidney disease, stage 4
0.868 0.132 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.867 0.133 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.867 0.133 0.000
N13 Obstructive and reflux uropathy
0.866 0.134 0.000
E10.4 With neurological complications
0.860 0.140 0.000
N30-N39 Other diseases of urinary system
0.858 0.142 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.855 0.145 0.000
I31.3 Pericardial effusion (noninflammatory)
0.855 0.145 0.000
G20-G26 Extrapyramidal and movement disorders
0.853 0.147 0.000
N20 Calculus of kidney and ureter
0.853 0.147 0.000
N75.1 Abscess of Bartholin's gland
0.853 0.147 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.849 0.151 0.000
S80-S89 Injuries to the knee and lower leg
0.848 0.151 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.845 0.155 0.000
E83 Disorders of mineral metabolism
0.845 0.155 0.000
I95.1 Orthostatic hypotension
0.841 0.159 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.841 0.159 0.000
I73.9 Peripheral vascular disease, unspecified
0.840 0.160 0.000
G90-G99 Other disorders of the nervous system
0.839 0.161 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.838 0.162 0.000
D86 Sarcoidosis
0.837 0.163 0.000
O80 Single spontaneous delivery
0.836 0.164 0.000
N18.5 Chronic kidney disease, stage 5
0.835 0.165 0.000
N32 Other disorders of bladder
0.828 0.172 0.000
Chapter X Diseases of the respiratory system
0.828 0.172 0.000
I77 Other disorders of arteries and arterioles
0.827 0.173 0.000
E10.2 With renal complications
0.825 0.175 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.824 0.176 0.000
N80-N98 Noninflammatory disorders of female genital tract
0.821 0.179 0.000
I05 Rheumatic mitral valve diseases
0.819 0.181 0.000
B97 Viral agents as the cause of diseases classified to other chapters
0.819 0.181 0.000
B96.2 Escherichia coli [E. coli] as the cause of diseases classified to other chapters
0.818 0.182 0.000
I44.1 Atrioventricular block, second degree
0.818 0.182 0.000
C25 Malignant neoplasm of pancreas
0.815 0.185 0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium
0.814 0.185 0.000
Chapter XXII Codes for special purposes
0.814 0.186 0.000
V23 Motorcycle rider injured in collision with car, pick-up truck or van
0.814 0.186 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.814 0.186 0.000
N32.0 Bladder-neck obstruction
0.813 0.187 0.000
I33 Acute and subacute endocarditis
0.811 0.189 0.000
O47 False labour
0.810 0.190 0.000
I25.1 Atherosclerotic heart disease
0.805 0.195 0.000
I22.9 Subsequent myocardial infarction of unspecified site
0.804 0.196 0.000
N00-N08 Glomerular diseases
0.803 0.197 0.000
B95.5 Unspecified streptococcus as the cause of diseases classified to other chapters
0.797 0.203 0.000
E14.9 Without complications
0.795 0.205 0.000
E50-E64 Other nutritional deficiencies
0.794 0.206 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.794 0.206 0.000
S60 Superficial injury of wrist and hand
0.792 0.208 0.000
E89.0 Postprocedural hypothyroidism
0.792 0.208 0.000
I25.3 Aneurysm of heart
0.792 0.208 0.000
N17.9 Acute renal failure, unspecified
0.788 0.212 0.000
N80 Endometriosis
0.788 0.212 0.000
N12 Tubulo-interstitial nephritis, not specified as acute or chronic
0.786 0.214 0.000
S70-S79 Injuries to the hip and thigh
0.785 0.215 0.000
O34 Maternal care for known or suspected abnormality of pelvic organs
0.785 0.215 0.000
I49 Other cardiac arrhythmias
0.784 0.216 0.000
N31 Neuromuscular dysfunction of bladder, not elsewhere classified
0.783 0.217 0.000
E86 Volume depletion
0.783 0.217 0.000
T78 Adverse effects, not elsewhere classified
0.782 0.218 0.000
O44 Placenta praevia
0.782 0.218 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.781 0.219 0.000
I08.3 Combined disorders of mitral, aortic and tricuspid valves
0.779 0.221 0.000
S90-S99 Injuries to the ankle and foot
0.778 0.222 0.000
I37 Pulmonary valve disorders
0.778 0.222 0.000
I63 Cerebral infarction
0.778 0.222 0.000
I34.1 Mitral (valve) prolapse
0.777 0.223 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.777 0.223 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.776 0.224 0.000
N10 Acute tubulo-interstitial nephritis
0.775 0.225 0.000
G25 Other extrapyramidal and movement disorders
0.772 0.228 0.000
N94 Pain and other conditions associated with female genital organs and menstrual cycle
0.772 0.228 0.000
N20.2 Calculus of kidney with calculus of ureter
0.768 0.232 0.000
I51.7 Cardiomegaly
0.768 0.232 0.000
W00-W19 Falls
0.767 0.233 0.000
O80.0 Spontaneous vertex delivery
0.766 0.234 0.000
B15-B19 Viral hepatitis
0.766 0.234 0.000
V23.4 Driver injured in traffic accident
0.765 0.235 0.000
O99.0 Anaemia complicating pregnancy, childbirth and the puerperium
0.765 0.235 0.000
J90-J94 Other diseases of pleura
0.764 0.236 0.000
I70 Atherosclerosis
0.762 0.238 0.000
T68 Hypothermia
0.759 0.241 0.000
N13.2 Hydronephrosis with renal and ureteral calculous obstruction
0.758 0.242 0.000
A80-A89 Viral infections of the central nervous system
0.758 0.242 0.000
O36 Maternal care for other known or suspected foetal problems
0.755 0.245 0.000
C20 Malignant neoplasm of rectum
0.754 0.246 0.000
I35.1 Aortic (valve) insufficiency
0.754 0.246 0.000
N75.0 Cyst of Bartholin's gland
0.753 0.247 0.000
O26 Maternal care for other conditions predominantly related to pregnancy
0.753 0.247 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.753 0.247 0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified
0.751 0.249 0.000
I24 Other acute ischaemic heart diseases
0.750 0.250 0.000
B95.0 Streptococcus, group A, as the cause of diseases classified to other chapters
0.747 0.253 0.000
E13 Other specified diabetes mellitus
0.746 0.254 0.000
I26 Pulmonary embolism
0.746 0.254 0.000
V40-V49 Car occupant injured in transport accident
0.745 0.254 0.000
J95-J99 Other diseases of the respiratory system
0.745 0.254 0.000
T79-T79 Certain early complications of trauma
0.745 0.255 0.000
I77.1 Stricture of artery
0.745 0.255 0.000
V80-V89 Other land transport accidents
0.745 0.255 0.000
I62 Other nontraumatic intracranial haemorrhage
0.745 0.255 0.000
I67 Other cerebrovascular diseases
0.742 0.258 0.000
X20-X29 Contact with venomous animals and plants
0.741 0.259 0.000
I69 Sequelae of cerebrovascular disease
0.741 0.259 0.000
I07 Rheumatic tricuspid valve diseases
0.740 0.260 0.000
B65-B83 Helminthiases
0.739 0.261 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.739 0.261 0.000
N25-N29 Other disorders of kidney and ureter
0.739 0.261 0.000
C25.9 Pancreas, unspecified
0.737 0.263 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.736 0.264 0.000
I35.2 Aortic (valve) stenosis with insufficiency
0.735 0.265 0.000
N13.5 Kinking and stricture of ureter without hydronephrosis
0.731 0.269 0.000
E83.5 Disorders of calcium metabolism
0.729 0.271 0.000
B96.3 Haemophilus influenzae [H. influenzae] as the cause of diseases classified to other chapters
0.729 0.271 0.000
I44.2 Atrioventricular block, complete
0.729 0.271 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.728 0.272 0.000
I08.1 Disorders of both mitral and tricuspid valves
0.728 0.272 0.000
N20.9 Urinary calculus, unspecified
0.726 0.274 0.000
N97 Female infertility
0.726 0.274 0.000
O82 Single delivery by Caesarean section
0.726 0.274 0.000
O41 Other disorders of amniotic fluid and membranes
0.726 0.274 0.000
E22 Hyperfunction of pituitary gland
0.725 0.275 0.000
D86.9 Sarcoidosis, unspecified
0.724 0.276 0.000
I51.9 Heart disease, unspecified
0.723 0.277 0.000
D86.8 Sarcoidosis of other and combined sites
0.723 0.277 0.000
N80.3 Endometriosis of pelvic peritoneum
0.723 0.277 0.000
S89 Other and unspecified injuries of lower leg
0.722 0.278 0.000
I35.9 Aortic valve disorder, unspecified
0.722 0.278 0.000
E27 Other disorders of adrenal gland
0.722 0.278 0.000
S40-S49 Injuries to the shoulder and upper arm
0.721 0.279 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.719 0.281 0.000
N13.6 Pyonephrosis
0.719 0.281 0.000
N21 Calculus of lower urinary tract
0.718 0.282 0.000
C15 Malignant neoplasm of oesophagus
0.718 0.282 0.000
E00-E07 Disorders of thyroid gland
0.718 0.282 0.000
I52 Other heart disorders in diseases classified elsewhere
0.717 0.283 0.000
I48 Atrial fibrillation and flutter
0.717 0.283 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.717 0.283 0.000
I41 Myocarditis in diseases classified elsewhere
0.717 0.283 0.000
I40 Acute myocarditis
0.717 0.283 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.717 0.283 0.000
I36 Nonrheumatic tricuspid valve disorders
0.717 0.283 0.000
I32 Pericarditis in diseases classified elsewhere
0.717 0.283 0.000
I30 Acute pericarditis
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
E40-E46 Malnutrition
0.717 0.283 0.000
D68 Other coagulation defects
0.716 0.284 0.000
E12 Malnutrition-related diabetes mellitus
0.716 0.284 0.000
E10.8 With unspecified complications
0.715 0.285 0.000
E10.7 With multiple complications
0.715 0.285 0.000
E10.6 With other specified complications
0.715 0.285 0.000
E10.0 With coma
0.715 0.285 0.000
G20 Parkinson's disease
0.715 0.285 0.000
N80.8 Other endometriosis
0.715 0.285 0.000
I23 Certain current complications following acute myocardial infarction
0.714 0.285 0.000
T78.4 Allergy, unspecified
0.714 0.286 0.000
O26.8 Other specified pregnancy-related conditions
0.714 0.286 0.000
S60.8 Other superficial injuries of wrist and hand
0.714 0.286 0.000
G91 Hydrocephalus
0.714 0.286 0.000
I25.6 Silent myocardial ischaemia
0.714 0.286 0.000
I25.4 Coronary artery aneurysm
0.714 0.286 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.714 0.286 0.000
I44.6 Other and unspecified fascicular block
0.714 0.286 0.000
I44.5 Left posterior fascicular block
0.714 0.286 0.000
I44.4 Left anterior fascicular block
0.714 0.286 0.000
I44.3 Other and unspecified atrioventricular block
0.714 0.286 0.000
I60 Subarachnoid haemorrhage
0.713 0.287 0.000
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria
0.713 0.287 0.000
I35.8 Other aortic valve disorders
0.712 0.288 0.000
O85-O92 Complications predominantly related to the puerperium
0.711 0.289 0.000
I78 Diseases of capillaries
0.711 0.289 0.000
N18.8 Other chronic renal failure
0.709 0.291 0.000
N18.1 Chronic kidney disease, stage 1
0.709 0.291 0.000
N31.8 Other neuromuscular dysfunction of bladder
0.707 0.293 0.000
Y40 Systemic antibiotics
0.707 0.293 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.706 0.294 0.000
Y57 Other and unspecified drugs and medicaments
0.705 0.295 0.000
I27 Other pulmonary heart diseases
0.704 0.295 0.000
N94.3 Premenstrual tension syndrome
0.704 0.296 0.000
C64-C68 Malignant neoplasms of urinary tract
0.704 0.296 0.000
B99-B99 Other infectious diseases
0.702 0.298 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.702 0.298 0.000
B50-B64 Protozoal diseases
0.702 0.298 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.702 0.298 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.702 0.298 0.000
A75-A79 Rickettsioses
0.702 0.298 0.000
A70-A74 Other diseases caused by chlamydiae
0.702 0.298 0.000
A65-A69 Other spirochaetal diseases
0.702 0.298 0.000
A20-A28 Certain zoonotic bacterial diseases
0.702 0.298 0.000
A15-A19 Tuberculosis
0.702 0.298 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.702 0.298 0.000
Y35-Y36 Legal intervention and operations of war
0.702 0.298 0.000
Y10-Y34 Event of undetermined intent
0.702 0.298 0.000
Y00-Y09 Assault
0.702 0.298 0.000
X85-X99 Assault
0.702 0.298 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.702 0.298 0.000
X50-X57 Overexertion, travel and privation
0.702 0.298 0.000
X30-X39 Exposure to forces of nature
0.702 0.298 0.000
X10-X19 Contact with heat and hot substances
0.702 0.298 0.000
X00-X09 Exposure to smoke, fire and flames
0.702 0.298 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.702 0.298 0.000
W75-W84 Other accidental threats to breathing
0.702 0.298 0.000
W65-W74 Accidental drowning and submersion
0.702 0.298 0.000
W50-W64 Exposure to animate mechanical forces
0.702 0.298 0.000
V98-V99 Other and unspecified transport accidents
0.702 0.298 0.000
V95-V97 Air and space transport accidents
0.702 0.298 0.000
V90-V94 Water transport accidents
0.702 0.298 0.000
V70-V79 Bus occupant injured in transport accident
0.702 0.298 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.702 0.298 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.702 0.298 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.702 0.298 0.000
V01-V09 Pedestrian injured in transport accident
0.702 0.298 0.000
N89 Other noninflammatory disorders of vagina
0.701 0.299 0.000
B35-B49 Mycoses
0.699 0.301 0.000
I34.9 Nonrheumatic mitral valve disorder, unspecified
0.699 0.301 0.000
I34.8 Other nonrheumatic mitral valve disorders
0.699 0.301 0.000
I34.2 Nonrheumatic mitral (valve) stenosis
0.699 0.301 0.000
T33-T35 Frostbite
0.699 0.301 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.699 0.301 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.699 0.301 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.699 0.301 0.000
T00-T07 Injuries involving multiple body regions
0.699 0.301 0.000
S10-S19 Injuries to the neck
0.699 0.301 0.000
E16 Other disorders of pancreatic internal secretion
0.698 0.302 0.000
I71 Aortic aneurysm and dissection
0.697 0.303 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.697 0.303 0.000
I25.5 Ischaemic cardiomyopathy
0.696 0.304 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.696 0.304 0.000
D00-D09 In situ neoplasms
0.695 0.305 0.000
E83.4 Disorders of magnesium metabolism
0.695 0.305 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.695 0.305 0.000
I05.1 Rheumatic mitral insufficiency
0.695 0.305 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.694 0.306 0.000
I98 Other disorders of circulatory system in diseases classified elsewhere
0.693 0.307 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.693 0.307 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.693 0.307 0.000
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries
0.692 0.308 0.000
I72 Other aneurysm
0.692 0.308 0.000
B25-B34 Other viral diseases
0.691 0.309 0.000
E29 Testicular dysfunction
0.691 0.309 0.000
B97.7 Papillomavirus as the cause of diseases classified to other chapters
0.691 0.309 0.000
N70 Salpingitis and oophoritis
0.691 0.309 0.000
I99 Other and unspecified disorders of circulatory system
0.690 0.309 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.690 0.310 0.000
I51.0 Cardiac septal defect, acquired
0.690 0.310 0.000
G25.0 Essential tremor
0.690 0.310 0.000
N32.9 Bladder disorder, unspecified
0.689 0.311 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.689 0.311 0.000
B95.1 Streptococcus, group B, as the cause of diseases classified to other chapters
0.688 0.311 0.000
O47.9 False labour, unspecified
0.687 0.313 0.000
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.686 0.314 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.686 0.314 0.000
N77 Vulvovaginal ulceration and inflammation in diseases classified elsewhere
0.686 0.314 0.000
O42 Premature rupture of membranes
0.685 0.315 0.000
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria
0.684 0.316 0.000
I09 Other rheumatic heart diseases
0.684 0.316 0.000
I06 Rheumatic aortic valve diseases
0.684 0.316 0.000
I31.9 Disease of pericardium, unspecified
0.683 0.317 0.000
N16 Renal tubulo-interstitial disorders in diseases classified elsewhere
0.682 0.318 0.000
N15 Other renal tubulo-interstitial diseases
0.682 0.318 0.000
N14 Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions
0.682 0.318 0.000
N11 Chronic tubulo-interstitial nephritis
0.682 0.318 0.000
I49.8 Other specified cardiac arrhythmias
0.682 0.318 0.000
B98 Other specified infectious agents as the cause of diseases classified to other chapters
0.682 0.318 0.000
N20.1 Calculus of ureter
0.680 0.320 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.680 0.320 0.000
J98 Other respiratory disorders
0.680 0.320 0.000
A30-A49 Other bacterial diseases
0.679 0.321 0.000
C25.0 Head of pancreas
0.679 0.321 0.000
I95.2 Hypotension due to drugs
0.679 0.321 0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.678 0.321 0.000
S66.2 Injury of extensor muscle and tendon of thumb at wrist and hand level
0.678 0.322 0.000
N92 Excessive, frequent and irregular menstruation
0.677 0.323 0.000
E85 Amyloidosis
0.677 0.323 0.000
E84 Cystic fibrosis
0.677 0.323 0.000
E79 Disorders of purine and pyrimidine metabolism
0.677 0.323 0.000
E77 Disorders of glycoprotein metabolism
0.677 0.323 0.000
E76 Disorders of glycosaminoglycan metabolism
0.677 0.323 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.677 0.323 0.000
E74 Other disorders of carbohydrate metabolism
0.677 0.323 0.000
E73 Lactose intolerance
0.677 0.323 0.000
E72 Other disorders of amino-acid metabolism
0.677 0.323 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.677 0.323 0.000
E70 Disorders of aromatic amino-acid metabolism
0.677 0.323 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.677 0.323 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.676 0.324 0.000
D86.1 Sarcoidosis of lymph nodes
0.675 0.325 0.000
I33.0 Acute and subacute infective endocarditis
0.675 0.325 0.000
O44.1 Placenta praevia with haemorrhage
0.675 0.325 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.674 0.326 0.000
X60-X84 Intentional self-harm
0.674 0.326 0.000
O35 Maternal care for known or suspected foetal abnormality and damage
0.674 0.326 0.000
O32 Maternal care for known or suspected malpresentation of foetus
0.673 0.326 0.000
N94.9 Unspecified condition associated with female genital organs and menstrual cycle
0.674 0.326 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.673 0.327 0.000
N18.0 End-stage renal disease
0.673 0.327 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.673 0.327 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.672 0.328 0.000
N31.2 Flaccid neuropathic bladder, not elsewhere classified
0.672 0.328 0.000
E14.3 With ophthalmic complications
0.671 0.329 0.000
Y83.2 Surgical operation with anastomosis, bypass or graft
0.670 0.330 0.000
O34.2 Maternal care due to uterine scar from previous surgery
0.670 0.330 0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.670 0.330 0.000
S68 Traumatic amputation of wrist and hand
0.669 0.330 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.669 0.331 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.669 0.331 0.000
O45 Premature separation of placenta [abruptio placentae]
0.667 0.332 0.000
O43 Placental disorders
0.667 0.332 0.000
O33 Maternal care for known or suspected disproportion
0.667 0.332 0.000
O31 Complications specific to multiple gestation
0.667 0.332 0.000
O40 Polyhydramnios
0.667 0.332 0.000
B95.3 Streptococcus pneumoniae as the cause of diseases classified to other chapters
0.666 0.334 0.000
S80 Superficial injury of lower leg
0.665 0.335 0.000
J20-J22 Other acute lower respiratory infections
0.665 0.335 0.000
Y44 Agents primarily affecting blood constituents
0.664 0.335 0.000
N18.2 Chronic kidney disease, stage 2
0.664 0.336 0.000
D55-D59 Haemolytic anaemias
0.664 0.336 0.000
I42 Cardiomyopathy
0.662 0.338 0.000
S71 Open wound of hip and thigh
0.661 0.339 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.660 0.340 0.000
B95.2 Streptococcus, group D, as the cause of diseases classified to other chapters
0.659 0.341 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.659 0.341 0.000
I31.8 Other specified diseases of pericardium
0.659 0.341 0.000
I31.2 Haemopericardium, not elsewhere classified
0.659 0.341 0.000
I31.1 Chronic constrictive pericarditis
0.659 0.341 0.000
I31.0 Chronic adhesive pericarditis
0.659 0.341 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.659 0.341 0.000
N05 Unspecified nephritic syndrome
0.658 0.342 0.000
N99-N99 Other disorders of the genitourinary system
0.658 0.342 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.657 0.343 0.000
N74 Female pelvic inflammatory disorders in diseases classified elsewhere
0.657 0.343 0.000
N71 Inflammatory disease of uterus, except cervix
0.657 0.343 0.000
E87.7 Fluid overload
0.656 0.344 0.000
S66.7 Injury of multiple extensor muscles and tendons at wrist and hand level
0.656 0.344 0.000
I77.8 Other specified disorders of arteries and arterioles
0.655 0.345 0.000
O84 Multiple delivery
0.655 0.345 0.000
O83 Other assisted single delivery
0.655 0.345 0.000
O81 Single delivery by forceps and vacuum extractor
0.655 0.345 0.000
I61 Intracerebral haemorrhage
0.654 0.346 0.000
D89.2 Hypergammaglobulinaemia, unspecified
0.653 0.347 0.000
I26.9 Pulmonary embolism without mention of acute cor pulmonale
0.653 0.347 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.652 0.348 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.652 0.348 0.000
N34 Urethritis and urethral syndrome
0.651 0.349 0.000
S66.9 Injury of unspecified muscle and tendon at wrist and hand level
0.651 0.349 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.651 0.349 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.650 0.350 0.000
C16 Malignant neoplasm of stomach
0.650 0.350 0.000
O99.1 Other diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism complicating pregnancy, childbirth and the puerperium
0.649 0.351 0.000
I74 Arterial embolism and thrombosis
0.649 0.351 0.000
Q50-Q56 Congenital malformations of genital organs
0.649 0.351 0.000
W20-W49 Exposure to inanimate mechanical forces
0.649 0.351 0.000
S20-S29 Injuries to the thorax
0.649 0.351 0.000
N97.9 Female infertility, unspecified
0.648 0.352 0.000
N22 Calculus of urinary tract in diseases classified elsewhere
0.648 0.352 0.000
S61 Open wound of wrist and hand
0.648 0.352 0.000
O80.9 Single spontaneous delivery, unspecified
0.647 0.353 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.647 0.353 0.000
Y52 Agents primarily affecting the cardiovascular system
0.646 0.353 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.646 0.354 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.646 0.354 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.646 0.354 0.000
S69 Other and unspecified injuries of wrist and hand
0.646 0.354 0.000
S65 Injury of blood vessels at wrist and hand level
0.646 0.354 0.000
N94.1 Dyspareunia
0.644 0.356 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.643 0.357 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.643 0.357 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.643 0.357 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.642 0.358 0.000
Q60-Q64 Congenital malformations of the urinary system
0.642 0.358 0.000
S82 Fracture of lower leg, including ankle
0.641 0.359 0.000
E88 Other metabolic disorders
0.641 0.359 0.000
I67.8 Other specified cerebrovascular diseases
0.640 0.359 0.000
N92.3 Ovulation bleeding
0.640 0.359 0.000
O46 Antepartum haemorrhage, not elsewhere classified
0.640 0.360 0.000
T75 Effects of other external causes
0.640 0.360 0.000
T74 Maltreatment syndromes
0.640 0.360 0.000
T73 Effects of other deprivation
0.640 0.360 0.000
T70 Effects of air pressure and water pressure
0.640 0.360 0.000
T69 Other effects of reduced temperature
0.640 0.360 0.000
T67 Effects of heat and light
0.640 0.360 0.000
T71 Asphyxiation
0.640 0.360 0.000
T66 Unspecified effects of radiation
0.640 0.360 0.000
G40-G47 Episodic and paroxysmal disorders
0.639 0.361 0.000
I05.9 Mitral valve disease, unspecified
0.639 0.361 0.000
Y60 Unintentional cut, puncture, perforation or haemorrhage during surgical and medical care
0.639 0.361 0.000
N80.1 Endometriosis of ovary
0.638 0.362 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.638 0.362 0.000
N75.9 Disease of Bartholin's gland, unspecified
0.637 0.362 0.000
N75.8 Other diseases of Bartholin's gland
0.637 0.362 0.000
O98 Maternal infectious and parasitic diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium
0.637 0.363 0.000
O97 Death from sequelae of direct obstetric causes
0.637 0.363 0.000
O96 Death from any obstetric cause occurring more than 42 days but less than one year after delivery
0.637 0.363 0.000
O95 Obstetric death of unspecified cause
0.637 0.363 0.000
O94 Sequelae of complication of pregnancy, childbirth and the puerperium
0.637 0.363 0.000
S62 Fracture at wrist and hand level
0.637 0.363 0.000
C51-C58 Malignant neoplasms of female genital organs
0.637 0.363 0.000
E14.8 With unspecified complications
0.636 0.364 0.000
E14.7 With multiple complications
0.636 0.364 0.000
E14.6 With other specified complications
0.636 0.364 0.000
E14.5 With peripheral circulatory complications
0.636 0.364 0.000
E14.4 With neurological complications
0.636 0.364 0.000
E14.2 Withrenal complications
0.636 0.364 0.000
E14.1 With ketoacidosis
0.636 0.364 0.000
E14.0 With coma
0.636 0.364 0.000
J91 Pleural effusion in conditions classified elsewhere
0.636 0.364 0.000
D84 Other immunodeficiencies
0.636 0.364 0.000
D83 Common variable immunodeficiency
0.636 0.364 0.000
D82 Immunodeficiency associated with other major defects
0.636 0.364 0.000
D81 Combined immunodeficiencies
0.636 0.364 0.000
D80 Immunodeficiency with predominantly antibody defects
0.636 0.364 0.000
G70-G73 Diseases of myoneural junction and muscle
0.636 0.364 0.000
J93 Pneumothorax
0.635 0.364 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.635 0.365 0.000
J98.1 Pulmonary collapse
0.635 0.365 0.000
I73.8 Other specified peripheral vascular diseases
0.634 0.366 0.000
I73.1 Thromboangiitis obliterans [Buerger]
0.634 0.366 0.000
V29 Motorcycle rider injured in other and unspecified transport accidents
0.633 0.367 0.000
V28 Motorcycle rider injured in noncollision transport accident
0.633 0.367 0.000
V27 Motorcycle rider injured in collision with fixed or stationary object
0.633 0.367 0.000
V26 Motorcycle rider injured in collision with other nonmotor vehicle
0.633 0.367 0.000
V25 Motorcycle rider injured in collision with railway train or railway vehicle
0.633 0.367 0.000
V24 Motorcycle rider injured in collision with heavy transport vehicle or bus
0.633 0.367 0.000
V22 Motorcycle rider injured in collision with two- or three-wheeled motor vehicle
0.633 0.367 0.000
V21 Motorcycle rider injured in collision with pedal cycle
0.633 0.367 0.000
V20 Motorcycle rider injured in collision with pedestrian or animal
0.633 0.367 0.000
G90 Disorders of autonomic nervous system
0.633 0.367 0.000
I22.8 Subsequent myocardial infarction of other sites
0.632 0.368 0.000
I22.0 Subsequent myocardial infarction of anterior wall
0.632 0.368 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.632 0.368 0.000
S89.9 Unspecified injury of lower leg
0.632 0.368 0.000
E23 Hypofunction and other disorders of pituitary gland
0.632 0.368 0.000
I38 Endocarditis, valve unspecified
0.632 0.368 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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