TreeWAS – Variant ID: rs57104699

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
C90.0 Multiple myeloma	0.000	0.047	0.953
C90 Multiple myeloma and malignant plasma cell neoplasms	0.000	0.383	0.617
C90.1 Plasma cell leukaemia	0.000	0.487	0.513
C90.3 Solitary plasmacytoma	0.000	0.562	0.437
C90.2 Plasmacytoma, extramedullary	0.000	0.635	0.365
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.000	0.655	0.345
C92 Myeloid leukaemia	0.000	0.663	0.337
C81 Hodgkin's disease	0.000	0.668	0.332
C92.1 Chronic myeloid leukaemia	0.000	0.676	0.324
C92.0 Acute myeloid leukaemia	0.000	0.694	0.306
C81.1 Nodular sclerosis	0.000	0.709	0.291
C81.2 Mixed cellularity	0.000	0.719	0.281
C81.0 Lymphocytic predominance	0.000	0.729	0.271
C81.9 Hodgkin's disease, unspecified	0.000	0.729	0.271
C92.9 Myeloid leukaemia, unspecified	0.000	0.738	0.262
C86 Other specified types of T/NK-cell lymphoma	0.000	0.747	0.253
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue	0.000	0.752	0.247
C94 Other leukaemias of specified cell type	0.000	0.752	0.247
C92.8 Acute myeloid leukaemia with multilineage dysplasia	0.000	0.758	0.242
C92.6 Acute myeloid leukaemia with 11q23-abnormality	0.000	0.758	0.242
C92.5 Acute myelomonocytic leukaemia	0.000	0.758	0.242
C92.3 Myeloid sarcoma	0.000	0.758	0.242
C92.2 Subacute myeloid leukaemia	0.000	0.758	0.242
C81.7 Other Hodgkin's disease	0.000	0.761	0.238
C81.4 Lymphocyte-rich classical Hodgkin lymphoma	0.000	0.761	0.238
C81.3 Lymphocytic depletion	0.000	0.761	0.238
C95 Leukaemia of unspecified cell type	0.000	0.762	0.238
C92.7 Other myeloid leukaemia	0.000	0.764	0.236
C93 Monocytic leukaemia	0.000	0.773	0.227
C82 Follicular [nodular] non-Hodgkin's lymphoma	0.000	0.780	0.220
C84 Peripheral and cutaneous T-cell lymphomas	0.000	0.783	0.217
C91 Lymphoid leukaemia	0.000	0.790	0.210
C86.5 Angioimmunoblastic T-cell lymphoma	0.000	0.813	0.187
C82.7 Other types of follicular non-Hodgkin's lymphoma	0.000	0.818	0.182
C86.6 Primary cutaneous CD30-positive T-cell proliferations	0.000	0.818	0.181
C86.4 Blastic NK-cell lymphoma	0.000	0.818	0.181
C86.3 Subcutaneous panniculitis-like T-cell lymphoma	0.000	0.818	0.181
C86.2 Enteropathy-type (intestinal) T-cell lymphoma	0.000	0.818	0.181
C86.1 Hepatosplenic T-cell lymphoma	0.000	0.818	0.181
C86.0 Extranodal NK/T-cell lymphoma, nasal type	0.000	0.818	0.181
C94.7 Other specified leukaemias	0.000	0.822	0.177
C94.6 Myelodysplastic and myeloproliferative disease, not elsewhere classified	0.000	0.822	0.177
C94.5 Acute myelofibrosis	0.000	0.822	0.177
C94.4 Acute panmyelosis	0.000	0.822	0.177
C94.3 Mast cell leukaemia	0.000	0.822	0.177
C94.2 Acute megakaryoblastic leukaemia	0.000	0.822	0.177
C94.1 Chronic erythraemia	0.000	0.822	0.177
C94.0 Acute erythraemia and erythroleukaemia	0.000	0.822	0.177
C96.9 Malignant neoplasms of lymphoid, haematopoietic and related tissue, unspecified	0.000	0.822	0.177
C96.8 Histiocytic sarcoma	0.000	0.822	0.177
C96.7 Other specified malignant neoplasms of lymphoid, haematopoietic and related tissue	0.000	0.822	0.177
C96.6 Unifocal Langerhans-cell histiocytosis	0.000	0.822	0.177
C96.5 Multifocal and unisystemic Langerhans-cell histiocytosis	0.000	0.822	0.177
C96.4 Sarcoma of dendritic cells (accessory cells)	0.000	0.822	0.177
C96.3 True histiocytic lymphoma	0.000	0.822	0.177
C96.2 Malignant mast cell tumour	0.000	0.822	0.177
C96.1 Malignant histiocytosis	0.000	0.822	0.177
C96.0 Letterer-Siwe disease	0.000	0.822	0.177
C88 Malignant immunoproliferative diseases	0.001	0.823	0.176
C84.4 Peripheral T-cell lymphoma	0.000	0.824	0.176
C92.4 Acute promyelocytic leukaemia	0.000	0.826	0.174
C82.0 Small cleaved cell, follicular	0.000	0.827	0.173
C82.1 Mixed small cleaved and large cell, follicular	0.000	0.828	0.172
C95.7 Other leukaemia of unspecified cell type	0.000	0.829	0.171
C95.2 Subacute leukaemia of unspecified cell type	0.000	0.829	0.171
C95.1 Chronic leukaemia of unspecified cell type	0.000	0.829	0.171
C95.0 Acute leukaemia of unspecified cell type	0.000	0.830	0.170
C91.9 Lymphoid leukaemia, unspecified	0.000	0.831	0.169
C91.0 Acute lymphoblastic leukaemia	0.000	0.835	0.165
C95.9 Leukaemia, unspecified	0.000	0.837	0.163
C93.9 Monocytic leukaemia, unspecified	0.000	0.837	0.163
C93.7 Other monocytic leukaemia	0.000	0.837	0.163
C93.3 Juvenile myelomonocytic leukaemia	0.000	0.837	0.163
C93.2 Subacute monocytic leukaemia	0.000	0.837	0.163
C93.0 Acute monocytic leukaemia	0.000	0.837	0.163
C82.3 Follicular lymphoma grade IIIa	0.000	0.838	0.162
C82.6 Cutaneous follicle centre lymphoma	0.000	0.842	0.158
C82.5 Diffuse follicle centre lymphoma	0.000	0.842	0.158
C84.0 Mycosis fungoides	0.000	0.844	0.156
C84.9 Mature T/NK-cell lymphoma, unspecified	0.000	0.844	0.156
C84.7 Anaplastic large cell lymphoma, ALK-negative	0.000	0.844	0.156
C84.6 Anaplastic large cell lymphoma, ALK-positive	0.000	0.844	0.156
C84.3 Lymphoepithelioid lymphoma	0.000	0.844	0.156
C84.2 T-zone lymphoma	0.000	0.844	0.156
C84.1 Sezary's diease	0.000	0.844	0.156
C91.8 Mature B-cell leukaemia Burkitt-type	0.000	0.849	0.151
C91.7 Other lymphoid leukaemia	0.000	0.849	0.151
C91.6 Prolymphocytic leukaemia of T-cell type	0.000	0.849	0.151
C91.3 Prolymphocytic leukaemia	0.000	0.849	0.151
C91.2 Subacute lymphocytic leukaemia	0.000	0.849	0.151
C91.1 Chronic lymphocytic leukaemia	0.000	0.857	0.143
C93.1 Chronic monocytic leukaemia	0.000	0.857	0.142
C82.4 Follicular lymphoma grade IIIb	0.000	0.858	0.141
C84.8 Cutaneous T-cell lymphoma, unspecified	0.000	0.863	0.137
C82.2 Large cell, follicular	0.000	0.866	0.133
C88.9 Malignant immunoproliferative disease, unspecified	0.001	0.873	0.126
C88.7 Other malignant immunoproliferative diseases	0.001	0.873	0.126
C88.3 Immunoproliferative small intestinal disease	0.001	0.873	0.126
C88.2 Gamma heavy chain disease	0.001	0.873	0.126
C88.1 Alpha heavy chain disease	0.001	0.873	0.126
C88.0 Waldenstrom's macroglobulinaemia	0.000	0.873	0.126
C91.4 Hairy-cell leukaemia	0.000	0.885	0.114
C91.5 Adult T-cell leukaemia	0.000	0.886	0.113
C84.5 Other and unspecified T-cell lymphomas	0.000	0.888	0.112
C85 Other and unspecified types of non-Hodgkin's lymphoma	0.000	0.921	0.079
C82.9 Follicular non-Hodgkin's lymphoma, unspecified	0.000	0.930	0.070
K61.0 Anal abscess	0.061	0.939	0.000
C88.4 Extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue [MALT-lymphoma]	0.002	0.943	0.055
C85.2 Mediastinal (thymic) large B-cell lymphoma	0.000	0.943	0.056
C85.0 Lymphosarcoma	0.000	0.943	0.056
C85.7 Other specified types of non-Hodgkin's lymphoma	0.000	0.945	0.054
K61 Abscess of anal and rectal regions	0.035	0.965	0.000
K61.2 Anorectal abscess	0.028	0.971	0.000
K61.1 Rectal abscess	0.028	0.971	0.000
K61.4 Intrasphincteric abscess	0.027	0.973	0.000
C83 Diffuse non-Hodgkin's lymphoma	0.000	0.975	0.025
Z80.0 Family history of malignant neoplasm of digestive organs	0.024	0.976	0.000
K61.3 Ischiorectal abscess	0.023	0.977	0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type	0.000	0.980	0.020
C83.6 Undifferentiated (diffuse)	0.000	0.982	0.018
C83.5 Lymphoblastic (diffuse)	0.000	0.982	0.018
C83.4 Immunoblastic (diffuse)	0.000	0.982	0.018
C83.2 Mixed small and large cell (diffuse)	0.000	0.984	0.016
I63.8 Other cerebral infarction	0.016	0.984	0.000
C83.1 Small cleaved cell (diffuse)	0.000	0.985	0.015
C83.8 Other types of diffuse non-Hodgkin's lymphoma	0.000	0.985	0.015
C83.7 Burkitt's tumour	0.001	0.987	0.013
C83.9 Diffuse non-Hodgkin's lymphoma, unspecified	0.000	0.987	0.013
N81.4 Uterovaginal prolapse, unspecified	0.000	0.987	0.013
C83.0 Small cell (diffuse)	0.000	0.987	0.012
C85.1 B-cell lymphoma, unspecified	0.000	0.988	0.012
K60.3 Anal fistula	0.009	0.991	0.000
C83.3 Large cell (diffuse)	0.000	0.992	0.008
K60.1 Chronic anal fissure	0.008	0.992	0.000
K60 Fissure and fistula of anal and rectal regions	0.007	0.993	0.000
C79.0 Secondary malignant neoplasm of kidney and renal pelvis	0.000	0.994	0.006
K60.4 Rectal fistula	0.006	0.994	0.000
C79.8 Secondary malignant neoplasm of other specified sites	0.000	0.994	0.006
H61.3 Acquired stenosis of external ear canal	0.006	0.994	0.000
Y42.5 Other oestrogens and progestogens	0.005	0.995	0.000
K60.5 Anorectal fistula	0.005	0.995	0.000
K05.3 Chronic periodontitis	0.000	0.995	0.005
K60.2 Anal fissure, unspecified	0.005	0.995	0.000
H61.0 Perichondritis of external ear	0.005	0.995	0.000
H61 Other disorders of external ear	0.005	0.995	0.000
J37.0 Chronic laryngitis	0.000	0.995	0.005
H61.8 Other specified disorders of external ear	0.004	0.996	0.000
F43.0 Acute stress reaction	0.000	0.996	0.004
F43 Reaction to severe stress, and adjustment disorders	0.000	0.996	0.004
F43.9 Reaction to severe stress, unspecified	0.000	0.996	0.004
C21.1 Anal canal	0.004	0.996	0.000
C71.9 Brain, unspecified	0.004	0.996	0.000
E87.0 Hyperosmolality and hypernatraemia	0.000	0.996	0.004
F43.2 Adjustment disorders	0.000	0.996	0.004
D68.2 Hereditary deficiency of other clotting factors	0.000	0.996	0.004
I80.0 Phlebitis and thrombophlebitis of superficial vessels of lower extremities	0.000	0.996	0.004
K60.0 Acute anal fissure	0.004	0.996	0.000
F43.1 Posttraumatic stress disorder	0.000	0.996	0.004
C71 Malignant neoplasm of brain	0.004	0.996	0.000
C79 Secondary malignant neoplasm of other sites	0.000	0.996	0.004
H61.9 Disorder of external ear, unspecified	0.004	0.996	0.000
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs	0.000	0.996	0.004
M25.31 Other instability of joint (Shoulder region)	0.004	0.996	0.000
S32.40 Fracture of acetabulum (closed)	0.000	0.996	0.003
C71.4 Occipital lobe	0.003	0.996	0.000
C71.2 Temporal lobe	0.003	0.997	0.000
S32.00 Fracture of lumbar vertebra (closed)	0.000	0.997	0.003
D80 Immunodeficiency with predominantly antibody defects	0.003	0.997	0.000
F43.8 Other reactions to severe stress	0.000	0.997	0.003
C71.7 Brain stem	0.003	0.997	0.000
H61.1 Non-infective disorders of pinna	0.003	0.997	0.000
C71.0 Cerebrum, except lobes and ventricles	0.003	0.997	0.000
C21 Malignant neoplasm of anus and anal canal	0.003	0.997	0.000
C21.8 Overlapping lesion of rectum, anus and anal canal	0.003	0.997	0.000
C71.6 Cerebellum	0.003	0.997	0.000
D80.4 Selective deficiency of immunoglobulin M [IgM]	0.003	0.997	0.000
D83.9 Common variable immunodeficiency, unspecified	0.003	0.997	0.000
R82.9 Other and unspecified abnormal finding in urine	0.003	0.997	0.000
S32.4 Fracture of acetabulum	0.000	0.997	0.003
L29.2 Pruritus vulvae	0.003	0.997	0.000
S32.0 Fracture of lumbar vertebra	0.000	0.997	0.003
S81.9 Open wound of lower leg, part unspecified	0.000	0.997	0.003
C71.5 Cerebral ventricle	0.003	0.997	0.000
M90.78 Fracture of bone in neoplastic disease (Other)	0.000	0.997	0.003
D80.9 Immunodeficiency with predominantly antibody defects, unspecified	0.003	0.997	0.000
D80.2 Selective deficiency of immunoglobulin A [IgA]	0.003	0.997	0.000
D80.1 Nonfamilial hypogammaglobulinaemia	0.003	0.997	0.000
T18.5 Foreign body in anus and rectum	0.003	0.997	0.000
C21.0 Anus, unspecified	0.003	0.997	0.000
D84.8 Other specified immunodeficiencies	0.003	0.997	0.000
D84 Other immunodeficiencies	0.003	0.997	0.000
D80.6 Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinaemia	0.003	0.997	0.000
D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses	0.003	0.997	0.000
C71.8 Overlapping lesion of brain	0.003	0.997	0.000
D83 Common variable immunodeficiency	0.003	0.997	0.000
D47.2 Monoclonal gammopathy	0.000	0.997	0.003
N73.9 Female pelvic inflammatory disease, unspecified	0.003	0.997	0.000
C71.3 Parietal lobe	0.003	0.997	0.000
C71.1 Frontal lobe	0.003	0.997	0.000
R90.0 Intracranial space-occupying lesion	0.003	0.997	0.000
S32 Fracture of lumbar spine and pelvis	0.000	0.997	0.003
D80.8 Other immunodeficiencies with predominantly antibody defects	0.003	0.997	0.000
D80.7 Transient hypogammaglobulinaemia of infancy	0.003	0.997	0.000
D80.5 Immunodeficiency with increased immunoglobulin M [IgM]	0.003	0.997	0.000
D80.0 Hereditary hypogammaglobulinaemia	0.003	0.997	0.000
D80-D89 Certain disorders involving the immune mechanism	0.003	0.997	0.000
C79.2 Secondary malignant neoplasm of skin	0.000	0.997	0.003
C79.6 Secondary malignant neoplasm of ovary	0.000	0.997	0.003
D84.9 Immunodeficiency, unspecified	0.003	0.997	0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow	0.000	0.997	0.003
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system	0.000	0.997	0.002
M90.75 Fracture of bone in neoplastic disease (Pelvic region and thigh)	0.000	0.997	0.003
C21.2 Cloacogenic zone	0.002	0.997	0.000
S32.5 Fracture of pubis	0.000	0.997	0.003
D68.6 Other Thrombophilia	0.000	0.997	0.003
K05 Gingivitis and periodontal diseases	0.000	0.997	0.003
U88 Agent resistant to multiple antibiotics	0.000	0.997	0.002
S32.41 Fracture of acetabulum (open)	0.000	0.998	0.002
M90.7 Fracture of bone in neoplastic disease	0.000	0.998	0.002
C79.7 Secondary malignant neoplasm of adrenal gland	0.000	0.998	0.002
J32.2 Chronic ethmoidal sinusitis	0.000	0.998	0.002
K91.8 Other postprocedural disorders of digestive system, not elsewhere classified	0.002	0.998	0.000
U89.8 Agent resistant to other single specified antibiotic	0.000	0.998	0.002
D68 Other coagulation defects	0.000	0.998	0.002
S32.01 Fracture of lumbar vertebra (open)	0.000	0.998	0.002
S32.50 Fracture of pubis (closed)	0.000	0.998	0.002
S32.3 Fracture of ilium	0.000	0.998	0.002
C67.4 Posterior wall of bladder	0.000	0.998	0.002
D44.3 Pituitary gland	0.002	0.998	0.000
D84.1 Defects in the complement system	0.002	0.998	0.000
K05.0 Acute gingivitis	0.000	0.998	0.002
D84.0 Lymphocyte function antigen-1 [LFA-1] defect	0.002	0.998	0.000
S62.30 Fracture of other metacarpal bone (closed)	0.000	0.998	0.002
D83.8 Other common variable immunodeficiencies	0.002	0.998	0.000
D83.2 Common variable immunodeficiency with autoantibodies to B- or T-cells	0.002	0.998	0.000
D83.1 Common variable immunodeficiency with predominant immunoregulatory T-cell disorders	0.002	0.998	0.000
D83.0 Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function	0.002	0.998	0.000
M90.72 Fracture of bone in neoplastic disease (Upper arm)	0.000	0.998	0.002
D68.3 Haemorrhagic disorder due to circulating anticoagulants	0.000	0.998	0.002
K05.5 Other periodontal diseases	0.000	0.998	0.002
S32.8 Fracture of other and unspecified parts of lumbar spine and pelvis	0.000	0.998	0.002
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms	0.002	0.998	0.000
S32.30 Fracture of ilium (closed)	0.000	0.998	0.002
D82 Immunodeficiency associated with other major defects	0.002	0.998	0.000
S32.2 Fracture of coccyx	0.000	0.998	0.002
C44.6 Skin of upper limb, including shoulder	0.000	0.998	0.002
D81 Combined immunodeficiencies	0.002	0.998	0.000
U89 Agent resistant to other and unspecified antibiotics	0.000	0.998	0.002
D86 Sarcoidosis	0.002	0.998	0.000
S32.1 Fracture of sacrum	0.000	0.998	0.002
D68.9 Coagulation defect, unspecified	0.000	0.998	0.002
S32.51 Fracture of pubis (open)	0.000	0.998	0.002
K05.1 Chronic gingivitis	0.000	0.998	0.002
M90.71 Fracture of bone in neoplastic disease (Shoulder region)	0.000	0.998	0.002
D30.0 Kidney	0.002	0.998	0.000
H52.0 Hypermetropia	0.000	0.998	0.002
K05.2 Acute periodontitis	0.000	0.998	0.002
K05.4 Periodontosis	0.000	0.998	0.002
S82.00 Fracture of patella (closed)	0.000	0.998	0.002
D68.4 Acquired coagulation factor deficiency	0.000	0.998	0.002
M90.79 Fracture of bone in neoplastic disease (Site unspecified)	0.000	0.998	0.002
M90.77 Fracture of bone in neoplastic disease (Ankle and foot)	0.000	0.998	0.002
M90.74 Fracture of bone in neoplastic disease (Hand)	0.000	0.998	0.002
M90.73 Fracture of bone in neoplastic disease (Forearm)	0.000	0.998	0.002
C79.9 Secondary malignant neoplasm, unspecified site	0.000	0.998	0.002
R23.2 Flushing	0.002	0.998	0.000
D44.0 Thyroid gland	0.002	0.998	0.000
S32.31 Fracture of ilium (open)	0.000	0.998	0.002
M06.49 Inflammatory polyarthropathy (Site unspecified)	0.002	0.998	0.000
M65.84 Other synovitis and tenosynovitis (Hand)	0.002	0.998	0.000
D86.0 Sarcoidosis of lung	0.002	0.998	0.000
S32.80 Fracture of other and unspecified parts of lumbar spine and pelvis (closed)	0.000	0.998	0.002
S82.31 Fracture of lower end of tibia (open)	0.000	0.998	0.002
D51.9 Vitamin B12 deficiency anaemia, unspecified	0.000	0.998	0.002
D61.9 Aplastic anaemia, unspecified	0.000	0.998	0.002
K75.4 Autoimmune hepatitis	0.000	0.998	0.002
U82-U85 Resistance to antimicrobial and antineoplastic drugs	0.000	0.998	0.002
D68.8 Other specified coagulation defects	0.000	0.998	0.002
M90.76 Fracture of bone in neoplastic disease (Lower leg)	0.000	0.998	0.002
D86.8 Sarcoidosis of other and combined sites	0.002	0.998	0.000
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes	0.002	0.998	0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified	0.001	0.998	0.001
J37 Chronic laryngitis and laryngotracheitis	0.000	0.998	0.002
D89.2 Hypergammaglobulinaemia, unspecified	0.000	0.998	0.002
S32.81 Fracture of other and unspecified parts of lumbar spine and pelvis (open)	0.000	0.998	0.002
D68.5 Primary Thrombophilia	0.000	0.998	0.002
D82.1 Di George's syndrome	0.002	0.998	0.000
U89.9 Agent resistant to unspecified antibiotic	0.000	0.998	0.002
D82.9 Immunodeficiency associated with major defect, unspecified	0.002	0.998	0.000
D82.8 Immunodeficiency associated with other specified major defects	0.002	0.998	0.000
D82.4 Hyperimmunoglobulin E [IgE] syndrome	0.002	0.998	0.000
D82.3 Immunodeficiency following hereditary defective response to Epstein-Barr virus	0.002	0.998	0.000
D82.2 Immunodeficiency with short-limbed stature	0.002	0.998	0.000
D82.0 Wiskott-Aldrich syndrome	0.002	0.998	0.000
O43.1 Malformation of placenta	0.002	0.998	0.000
S32.21 Fracture of coccyx (open)	0.000	0.998	0.002
S32.20 Fracture of coccyx (closed)	0.000	0.998	0.002
L65.9 Nonscarring hair loss, unspecified	0.000	0.998	0.002
O70.0 First degree perineal laceration during delivery	0.000	0.998	0.002
D81.9 Combined immunodeficiency, unspecified	0.002	0.998	0.000
D81.8 Other combined immunodeficiencies	0.002	0.998	0.000
D81.7 Major histocompatibility complex class II deficiency	0.002	0.998	0.000
D81.6 Major histocompatibility complex class I deficiency	0.002	0.998	0.000
D81.5 Purine nucleoside phosphorylase [PNP] deficiency	0.002	0.998	0.000
D81.4 Nezelof's syndrome	0.002	0.998	0.000
D81.3 Adenosine deaminase [ADA] deficiency	0.002	0.998	0.000
D81.2 Severe combined immunodeficiency [SCID] with low or normal B-cell numbers	0.002	0.998	0.000
D81.1 Severe combined immunodeficiency [SCID] with low T- and B-cell numbers	0.002	0.998	0.000
D81.0 Severe combined immunodeficiency [SCID] with reticular dysgenesis	0.002	0.998	0.000
M90.70 Fracture of bone in neoplastic disease (Multiple sites)	0.000	0.998	0.002
S82.50 Fracture of medial malleolus (closed)	0.002	0.998	0.000
S32.11 Fracture of sacrum (open)	0.000	0.998	0.002
C66 Malignant neoplasm of ureter	0.000	0.998	0.002
M79.79 Fibromyalgia (Site unspecified)	0.002	0.998	0.000
W50.9 Unspecified place	0.002	0.998	0.000
S32.7 Multiple fractures of lumbar spine and pelvis	0.000	0.998	0.002
D68.1 Hereditary factor XI deficiency	0.000	0.998	0.002
D89.9 Disorder involving the immune mechanism, unspecified	0.001	0.998	0.000
K05.22 Aggressive periodontitis, generalized	0.000	0.998	0.002
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.002	0.998	0.000
M71.26 Synovial cyst of popliteal space [Baker]-Lower Leg	0.002	0.998	0.000
S32.10 Fracture of sacrum (closed)	0.000	0.998	0.002
D44.7 Aortic body and other paraganglia	0.002	0.998	0.000
K10.8 Other specified diseases of jaws	0.002	0.998	0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands	0.002	0.998	0.000
D01.3 Anus and anal canal	0.002	0.998	0.000
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms	0.002	0.998	0.000
U84 Resistance to other antimicrobial drugs	0.000	0.998	0.002
U83 Resistance to other antibiotics	0.000	0.998	0.002
U82 Resistance to betalactam antibiotics	0.000	0.998	0.002
U85 Resistance to antineoplastic drugs	0.000	0.998	0.002
D86.9 Sarcoidosis, unspecified	0.002	0.998	0.000
D89.8 Other specified disorders involving the immune mechanism, not elsewhere classified	0.001	0.998	0.001
D89.3 Immune reconstitution syndrome	0.001	0.998	0.001
J37.1 Chronic laryngotracheitis	0.000	0.998	0.002
J95.8 Other postprocedural respiratory disorders	0.000	0.998	0.002
C70 Malignant neoplasm of meninges	0.002	0.998	0.000
H60-H62 Diseases of external ear	0.002	0.998	0.000
M06.40 Inflammatory polyarthropathy (Multiple sites)	0.002	0.998	0.000
C70.0 Cerebral meninges	0.002	0.998	0.000
J98.0 Diseases of bronchus, not elsewhere classified	0.000	0.998	0.002
R68.0 Hypothermia, not associated with low environmental temperature	0.000	0.998	0.002
C72 Malignant neoplasm of spinal cord, cranial nerves and other parts of central nervous system	0.002	0.998	0.000
F31.7 Bipolar affective disorder, currently in remission	0.002	0.998	0.000
O75.0 Maternal distress during labour and delivery	0.002	0.998	0.000
T17.5 Foreign body in bronchus	0.002	0.998	0.000
S00.3 Superficial injury of nose	0.002	0.998	0.000
F31 Bipolar affective disorder	0.002	0.998	0.000
T18 Foreign body in alimentary tract	0.002	0.998	0.000
D86.3 Sarcoidosis of skin	0.001	0.998	0.000
D89.1 Cryoglobulinaemia	0.001	0.998	0.001
Y52.5 Other antihypertensive drugs, not elsewhere classified	0.002	0.998	0.000
M43.06 Spondylolysis (Lumbar region)	0.002	0.998	0.000
C72.0 Spinal cord	0.001	0.998	0.000
D89.0 Polyclonal hypergammaglobulinaemia	0.001	0.998	0.001
K63.9 Disease of intestine, unspecified	0.000	0.998	0.002
M81.40 Drug-induced osteoporosis (Multiple sites)	0.000	0.998	0.002
S32.71 Multiple fractures of lumbar spine and pelvis (open)	0.000	0.998	0.001
D44.8 Pluriglandular involvement	0.001	0.998	0.000
X49.9 Unspecified place	0.002	0.998	0.000
M06.34 Rheumatoid nodule (Hand)	0.002	0.998	0.000
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms	0.002	0.998	0.000
D86.1 Sarcoidosis of lymph nodes	0.001	0.998	0.000
F31.8 Other bipolar affective disorders	0.001	0.998	0.000
M22.3 Other derangements of patella	0.000	0.998	0.002
X69.9 Unspecified place	0.001	0.998	0.000
H62 Disorders of external ear in diseases classified elsewhere	0.001	0.998	0.000
D44.5 Pineal gland	0.001	0.998	0.000
D44.2 Parathyroid gland	0.001	0.998	0.000
O75.7 Vaginal delivery following previous Caesarean section	0.002	0.998	0.000
U82.9 Resistance to betalactam antibiotics, unspecified	0.000	0.998	0.001
U82.8 Resistance to other betalactam antibiotics	0.000	0.998	0.001
U82.2 Extended spectrum betalactamase (ESBL) resistance	0.000	0.998	0.001
U82.1 Resistance to methicillin	0.000	0.998	0.001
U82.0 Resistance to penicillin	0.000	0.998	0.001
U83.9 Resistance to unspecified antibiotic	0.000	0.998	0.001
U83.8 Resistance to other single specified antibiotic	0.000	0.998	0.001
U83.7 Resistance to multiple antibiotics	0.000	0.998	0.001
U83.2 Resistance to quinolones	0.000	0.998	0.001
U83.1 Resistance to other vancomycin related antibiotics	0.000	0.998	0.001
U83.0 Resistance to vancomycin	0.000	0.998	0.001
U84.9 Resistance to unspecified antimicrobial drugs	0.000	0.998	0.001
U84.8 Resistance to other specified antimicrobial drug	0.000	0.998	0.001
U84.7 Resistance to multiple antimicrobial drugs	0.000	0.998	0.001
U84.3 Resistance to tuberculostatic drug(s)	0.000	0.998	0.001
U84.2 Resistance to antiviral drug(s)	0.000	0.998	0.001
U84.1 Resistance to antifungal drug(s)	0.000	0.998	0.001
U84.0 Resistance to antiparasitic drug(s)	0.000	0.998	0.001
M65.81 Other synovitis and tenosynovitis (Shoulder region)	0.001	0.998	0.000
M71.96 Bursopathy, unspecified (Lower leg)	0.001	0.998	0.000
C70.9 Meninges, unspecified	0.001	0.998	0.000
C70.1 Spinal meninges	0.001	0.998	0.000
D44.9 Endocrine gland, unspecified	0.001	0.998	0.000
M06.4 Inflammatory polyarthropathy	0.001	0.999	0.000
T18.3 Foreign body in small intestine	0.001	0.999	0.000
T59.8 Other specified gases, fumes and vapours	0.001	0.999	0.000
X69.0 Home	0.001	0.999	0.000
M71.95 Bursopathy, unspecified (Pelvic region and thigh)	0.001	0.999	0.000
C72.9 Central nervous system, unspecified	0.001	0.999	0.000
C72.8 Overlapping lesion of brain and other parts of central nervous system	0.001	0.999	0.000
C72.5 Other and unspecified cranial nerves	0.001	0.999	0.000
C72.4 Acoustic nerve	0.001	0.999	0.000
C72.3 Optic nerve	0.001	0.999	0.000
C72.2 Olfactory nerve	0.001	0.999	0.000
C72.1 Cauda equina	0.001	0.999	0.000
F31.3 Bipolar affective disorder, current episode mild or moderate depression	0.001	0.999	0.000
J98.5 Diseases of mediastinum, not elsewhere classified	0.000	0.999	0.001
M65.8 Other synovitis and tenosynovitis	0.001	0.999	0.000
S56.4 Injury of extensor muscle and tendon of other finger(s) at forearm level	0.001	0.999	0.000
M25.33 Other instability of joint (Forearm)	0.001	0.999	0.000
D44.1 Adrenal gland	0.001	0.999	0.000
I35.1 Aortic (valve) insufficiency	0.000	0.999	0.001
K52.8 Other specified non-infective gastro-enteritis and colitis	0.001	0.999	0.000
M25.3 Other instability of joint	0.001	0.999	0.000
M71.9 Bursopathy, unspecified	0.001	0.999	0.000
M65.83 Other synovitis and tenosynovitis (Forearm)	0.001	0.999	0.000
C34.1 Upper lobe, bronchus or lung	0.000	0.999	0.001
H62.0 Otitis externa in bacterial diseases classified elsewhere	0.001	0.999	0.000
T18.8 Foreign body in other and multiple parts of alimentary tract	0.001	0.999	0.000
T18.4 Foreign body in colon	0.001	0.999	0.000
M65.86 Other synovitis and tenosynovitis (Lower leg)	0.001	0.999	0.000
D44.4 Craniopharyngeal duct	0.001	0.999	0.000
M71.2 Synovial cyst of popliteal space [Baker]	0.001	0.999	0.000
R59.0 Localised enlarged lymph nodes	0.000	0.999	0.001
S81.7 Multiple open wounds of lower leg	0.000	0.999	0.001
T18.1 Foreign body in oesophagus	0.001	0.999	0.000
X69 Intentional self-poisoning by and exposure to other and unspecified chemicals and noxious substances	0.001	0.999	0.000
C79.3 Secondary malignant neoplasm of brain and cerebral meninges	0.000	0.999	0.001
H61.2 Impacted cerumen	0.001	0.999	0.000
X60.8 Other specified place	0.001	0.999	0.000
M19.01 Primary arthrosis of other joints (Shoulder region)	0.001	0.999	0.000
M71.97 Bursopathy, unspecified (Ankle and foot)	0.001	0.999	0.000
H62.8 Other disorders of external ear in diseases classified elsewhere	0.001	0.999	0.000
H62.4 Otitis externa in other diseases classified elsewhere	0.001	0.999	0.000
H62.3 Otitis externa in other infectious and parasitic diseases classified elsewhere	0.001	0.999	0.000
H62.2 Otitis externa in mycoses	0.001	0.999	0.000
H62.1 Otitis externa in viral diseases classified elsewhere	0.001	0.999	0.000
O75.6 Delayed delivery after spontaneous or unspecified rupture of membranes	0.001	0.999	0.000
S82.0 Fracture of patella	0.000	0.999	0.001
X63.0 Home	0.001	0.999	0.000
S81 Open wound of lower leg	0.000	0.999	0.001
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms	0.001	0.999	0.000
O32.0 Maternal care for unstable lie	0.000	0.999	0.001
O75.9 Complication of labour and delivery, unspecified	0.001	0.999	0.000
M19.03 Primary arthrosis of other joints (Forearm)	0.000	0.999	0.001
M71.92 Bursopathy, unspecified (Upper arm)	0.001	0.999	0.000
S82.01 Fracture of patella (open)	0.000	0.999	0.001
S00.1 Contusion of eyelid and periocular area	0.001	0.999	0.000
M06.48 Inflammatory polyarthropathy (Other)	0.001	0.999	0.000
M06.47 Inflammatory polyarthropathy (Ankle and foot)	0.001	0.999	0.000
M06.46 Inflammatory polyarthropathy (Lower leg)	0.001	0.999	0.000
M06.45 Inflammatory polyarthropathy (Pelvic region and thigh)	0.001	0.999	0.000
M06.44 Inflammatory polyarthropathy (Hand)	0.001	0.999	0.000
M06.43 Inflammatory polyarthropathy (Forearm)	0.001	0.999	0.000
M06.42 Inflammatory polyarthropathy (Upper arm)	0.001	0.999	0.000
M06.41 Inflammatory polyarthropathy (Shoulder region)	0.001	0.999	0.000
M91.20 Coxa plana-Mult sites	0.000	0.999	0.001
D44.6 Carotid body	0.001	0.999	0.000
J98.2 Interstitial emphysema	0.000	0.999	0.001
T18.2 Foreign body in stomach	0.001	0.999	0.000
O75 Other complications of labour and delivery, not elsewhere classified	0.001	0.999	0.000
M25.39 Other instability of joint (Site unspecified)	0.001	0.999	0.000
M25.38 Other instability of joint (Other)	0.001	0.999	0.000
M25.36 Other instability of joint (Lower leg)	0.001	0.999	0.000
M25.35 Other instability of joint (Pelvic region and thigh)	0.001	0.999	0.000
M25.32 Other instability of joint (Upper arm)	0.001	0.999	0.000
M25.30 Other instability of joint (Multiple sites)	0.001	0.999	0.000
M65.89 Other synovitis and tenosynovitis (Site unspecified)	0.001	0.999	0.000
M65.88 Other synovitis and tenosynovitis (Other)	0.001	0.999	0.000
M65.85 Other synovitis and tenosynovitis (Pelvic region and thigh)	0.001	0.999	0.000
M65.82 Other synovitis and tenosynovitis (Upper arm)	0.001	0.999	0.000
M65.80 Other synovitis and tenosynovitis (Multiple sites)	0.001	0.999	0.000
M71.99 Bursopathy, unspecified (Site unspecified)	0.001	0.999	0.000
M71.98 Bursopathy, unspecified (Other)	0.001	0.999	0.000
M71.94 Bursopathy, unspecified (Hand)	0.001	0.999	0.000
M71.93 Bursopathy, unspecified (Forearm)	0.001	0.999	0.000
M71.91 Bursopathy, unspecified (Shoulder region)	0.001	0.999	0.000
M71.90 Bursopathy, unspecified (Multiple sites)	0.001	0.999	0.000
I51.4 Myocarditis, unspecified	0.001	0.999	0.000
C67.0 Trigone of bladder	0.000	0.999	0.001
K05.6 Periodontal disease, unspecified	0.000	0.999	0.001
M71.29 Synovial cyst of popliteal space [Baker]-Site unspec	0.001	0.999	0.000
M71.28 Synovial cyst of popliteal space [Baker]-Other	0.001	0.999	0.000
M71.27 Synovial cyst of popliteal space [Baker]-Ankle/Foot	0.001	0.999	0.000
M71.25 Synovial cyst of popliteal space [Baker]-Pelvic/Thigh	0.001	0.999	0.000
M71.24 Synovial cyst of popliteal space [Baker]-Hand	0.001	0.999	0.000
M71.23 Synovial cyst of popliteal space [Baker]-Forearm	0.001	0.999	0.000
M71.22 Synovial cyst of popliteal space [Baker]-Upper arm	0.001	0.999	0.000
M71.21 Synovial cyst of popliteal space [Baker]-Shldr region	0.001	0.999	0.000
M71.20 Synovial cyst of popliteal space [Baker]-Mult sites	0.001	0.999	0.000
T18.0 Foreign body in mouth	0.001	0.999	0.000
X69.8 Other specified place	0.001	0.999	0.000
X69.7 Farm	0.001	0.999	0.000
X69.6 Industrial and construction area	0.001	0.999	0.000
X69.5 Trade and service area	0.001	0.999	0.000
X69.4 Street and highway	0.001	0.999	0.000
X69.3 Sports and athletics area	0.001	0.999	0.000
X69.2 School, other institution and public administrative area	0.001	0.999	0.000
X69.1 Residential institution	0.001	0.999	0.000
M76.67 Achilles tendinitis (Ankle and foot)	0.000	0.999	0.001

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations