TreeWAS – Variant ID: rs573521

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
S82.80 Fractures of other parts of lower leg (closed)	0.550	0.450	0.000
S82.8 Fractures of other parts of lower leg	0.150	0.850	0.000
S82.86 Maisonneuve's fracture	0.108	0.892	0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.103	0.897	0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.102	0.898	0.000
T42.1 Iminostilbenes	0.093	0.907	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.090	0.910	0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.090	0.910	0.000
T42.3 Barbiturates	0.084	0.916	0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.080	0.920	0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.080	0.920	0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.079	0.921	0.000
T42.0 Hydantoin derivatives	0.079	0.921	0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.076	0.924	0.000
T43.2 Other and unspecified antidepressants	0.075	0.925	0.000
T47.1 Other antacids and anti-gastric-secretion drugs	0.074	0.926	0.000
T42.5 Mixed antiepileptics, not elsewhere classified	0.073	0.926	0.000
T42.2 Succinimides and oxazolidinediones	0.073	0.926	0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.073	0.927	0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.073	0.927	0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.072	0.928	0.000
T50.9 Other and unspecified drugs, medicaments and biological substances	0.072	0.928	0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.069	0.931	0.000
T36 Poisoning by systemic antibiotics	0.069	0.931	0.000
S82.81 Fractures of other parts of lower leg (open)	0.067	0.932	0.000
T40.4 Other synthetic narcotics	0.066	0.934	0.000
T41 Poisoning by anaesthetics and therapeutic gases	0.065	0.935	0.000
T40.5 Cocaine	0.065	0.935	0.000
T43.5 Other and unspecified antipsychotics and neuroleptics	0.064	0.936	0.000
T43.0 Tricyclic and tetracyclic antidepressants	0.062	0.938	0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.062	0.938	0.000
T50.1 Loop [high-ceiling] diuretics	0.062	0.938	0.000
T50.4 Drugs affecting uric acid metabolism	0.061	0.939	0.000
T47.6 Antidiarrhoeal drugs	0.060	0.940	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.060	0.940	0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.059	0.940	0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.059	0.941	0.000
T50.8 Diagnostic agents	0.059	0.941	0.000
T45.4 Iron and its compounds	0.058	0.942	0.000
T47.9 Agent primarily affecting the gastro-intestinal system, unspecified	0.058	0.942	0.000
T47.8 Other agents primarily affecting the gastro-intestinal system	0.058	0.942	0.000
T47.7 Emetics	0.058	0.942	0.000
T47.5 Digestants	0.058	0.942	0.000
T47.3 Saline and osmotic laxatives	0.058	0.942	0.000
T47.2 Stimulant laxatives	0.058	0.942	0.000
T48.5 Anti-common-cold drugs	0.058	0.942	0.000
T47.4 Other laxatives	0.058	0.942	0.000
T43.8 Other psychotropic drugs, not elsewhere classified	0.057	0.942	0.000
T50.7 Analeptics and opioid receptor antagonists	0.057	0.943	0.000
T50.5 Appetite depressants	0.057	0.943	0.000
T50.3 Electrolytic, caloric and water-balance agents	0.057	0.943	0.000
T50.0 Mineralocorticoids and their antagonists	0.057	0.943	0.000
T40.2 Other opioids	0.057	0.943	0.000
T47.0 Histamine H(2)-receptor antagonists	0.055	0.945	0.000
T36.4 Tetracyclines	0.055	0.945	0.000
T40.3 Methadone	0.055	0.945	0.000
T40.9 Other and unspecified psychodysleptics [hallucinogens]	0.055	0.945	0.000
T40.8 Lysergide [LSD]	0.055	0.945	0.000
T40.7 Cannabis (derivatives)	0.055	0.945	0.000
T40.0 Opium	0.055	0.945	0.000
T43.4 Butyrophenone and thioxanthene neuroleptics	0.055	0.945	0.000
T45.1 Antineoplastic and immunosuppressive drugs	0.054	0.946	0.000
T48.6 Antiasthmatics, not elsewhere classified	0.054	0.946	0.000
T45.0 Antiallergic and antiemetic drugs	0.054	0.946	0.000
T49.0 Local antifungal, anti-infective and anti-inflammatory drugs, not elsewhere classified	0.053	0.947	0.000
T40.1 Heroin	0.053	0.947	0.000
T43.9 Psychotropic drug, unspecified	0.052	0.947	0.000
T45.2 Vitamins, not elsewhere classified	0.052	0.947	0.000
T45.9 Primarily systemic and haematological agent, unspecified	0.052	0.948	0.000
T45.8 Other primarily systemic and haematological agents	0.052	0.948	0.000
T45.7 Anticoagulant antagonists, vitamin K and other coagulants	0.052	0.948	0.000
T45.6 Fibrinolysis-affecting drugs	0.052	0.948	0.000
T45.3 Enzymes, not elsewhere classified	0.052	0.948	0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.052	0.948	0.000
T45.5 Anticoagulants	0.052	0.948	0.000
T48.7 Other and unspecified agents primarily acting on the respiratory system	0.052	0.948	0.000
T48.4 Expectorants	0.052	0.948	0.000
T48.3 Antitussives	0.052	0.948	0.000
T48.2 Other and unspecified agents primarily acting on muscles	0.052	0.948	0.000
T48.1 Skeletal muscle relaxants [neuromuscular blocking agents]	0.052	0.948	0.000
T48.0 Oxytocic drugs	0.052	0.948	0.000
T46.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.050	0.950	0.000
T46.4 Angiotensin-converting-enzyme inhibitors	0.050	0.950	0.000
T50.6 Antidotes and chelating agents, not elsewhere classified	0.050	0.950	0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics	0.050	0.950	0.000
T49.9 Topical agent, unspecified	0.049	0.950	0.000
T49.8 Other topical agents	0.049	0.950	0.000
T49.7 Dental drugs, topically applied	0.049	0.950	0.000
T49.6 Otorhinolaryngological drugs and preparations	0.049	0.950	0.000
T49.5 Ophthalmological drugs and preparations	0.049	0.950	0.000
T49.4 Keratolytics, keratoplastics and other hair treatment drugs and preparations	0.049	0.950	0.000
T49.3 Emollients, demulcents and protectants	0.049	0.950	0.000
T49.2 Local astringents and local detergents	0.049	0.950	0.000
T49.1 Antipruritics	0.049	0.950	0.000
T36.9 Systemic antibiotic, unspecified	0.049	0.950	0.000
T36.8 Other systemic antibiotics	0.049	0.950	0.000
T36.7 Antifungal antibiotics, systemically used	0.049	0.950	0.000
T36.6 Rifamycins	0.049	0.950	0.000
T36.5 Aminoglycosides	0.049	0.950	0.000
T36.2 Chloramphenicol group	0.049	0.950	0.000
T36.1 Cefalosporins and other Beta-lactam antibiotics	0.049	0.950	0.000
T36.0 Penicillins	0.049	0.951	0.000
T38.6 Antigonadotrophins. antioestrogens, antiandrogens, not elsewhere classified	0.047	0.952	0.000
T38.8 Other and unspecified hormones and their synthetic substitutes	0.047	0.952	0.000
T36.3 Macrolides	0.047	0.952	0.000
T41.5 Therapeutic gases	0.047	0.953	0.000
T41.4 Anaesthetic, unspecified	0.047	0.953	0.000
T41.3 Local anaesthetics	0.047	0.953	0.000
T41.2 Other and unspecified general anaesthetics	0.047	0.953	0.000
T41.1 Intravenous anaesthetics	0.047	0.953	0.000
T41.0 Inhaled anaesthetics	0.047	0.953	0.000
T43.6 Psychostimulants with abuse potential	0.045	0.955	0.000
T43.3 Phenothiazine antipsychotics and neuroleptics	0.043	0.956	0.000
T46.9 Other and unspecified agents primarily affecting the cardiovascular system	0.043	0.957	0.000
T46.8 Antivaricose drugs, including sclerosing agents	0.043	0.957	0.000
T46.7 Peripheral vasodilators	0.043	0.957	0.000
T46.0 Cardiac-stimulant glycosides and drugs of similar action	0.043	0.957	0.000
T46.3 Coronary vasodilators, not elsewhere classified	0.043	0.957	0.000
T37.9 Systemic anti-infective and antiparasitic, unspecified	0.043	0.957	0.000
T37.5 Antiviral drugs	0.043	0.957	0.000
T37.4 Anthelminthics	0.043	0.957	0.000
T37.3 Other antiprotozoal drugs	0.043	0.957	0.000
T37.2 Antimalarials and drugs acting on other blood protozoa	0.043	0.957	0.000
T37.1 Antimycobacterial drugs	0.043	0.957	0.000
T37.0 Sulphonamides	0.043	0.957	0.000
T38.9 Other and unspecified hormone antagonists	0.043	0.957	0.000
T38.7 Androgens and anabolic congeners	0.043	0.957	0.000
T38.5 Other oestrogens and progestogens	0.043	0.957	0.000
T38.4 Oral contraceptives	0.043	0.957	0.000
T38.2 Antithyroid drugs	0.043	0.957	0.000
T38.0 Glucocorticoids and synthetic analogues	0.043	0.957	0.000
T42.4 Benzodiazepines	0.042	0.958	0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified	0.042	0.958	0.000
T46.2 Other antidysrhythmic drugs, not elsewhere classified	0.041	0.959	0.000
T38.1 Thyroid hormones and substitutes	0.039	0.961	0.000
T46.5 Other antihypertensive drugs, not elsewhere classified	0.038	0.962	0.000
T44.8 Centrally acting and afrenergic-neuron-blocking agents, not elsewhere classified	0.038	0.962	0.000
T44.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified	0.038	0.962	0.000
T44.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified	0.038	0.962	0.000
T44.2 Ganglionic blocking drugs, not elsewhere classified	0.038	0.962	0.000
T44.1 Other parasympathomimetics [cholinergics]	0.038	0.962	0.000
T44.0 Anticholinesterase agents	0.038	0.962	0.000
T37.8 Other specified systemic anti-infectives and antiparasitics	0.037	0.963	0.000
T40.6 Other and unspecified narcotics	0.036	0.963	0.000
T44.9 Other and unspecified drugs primarily affecting the nervous system	0.036	0.964	0.000
T44.6 Alpha-Adrenoreceeptor antagonists, not elsewhere classified	0.036	0.964	0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.029	0.971	0.000
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.024	0.976	0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.022	0.978	0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified	0.021	0.978	0.000
T39.4 Antirheumatics, not elsewhere classified	0.021	0.979	0.000
T39.2 Pyrazolone derivatives	0.021	0.979	0.000
T39.0 Salicylates	0.020	0.980	0.000
T46.1 Calcium-channel blockers	0.017	0.982	0.001
H33.2 Serous retinal detachment	0.018	0.982	0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.018	0.982	0.000
T39.1 4-Aminophenol derivatives	0.016	0.984	0.000
K60.1 Chronic anal fissure	0.000	0.988	0.012
M65.91 Synovitis and tenosynovitis, unspecified (Shoulder region)	0.011	0.989	0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.011	0.989	0.000
D32.9 Meninges, unspecified	0.000	0.989	0.011
M65.93 Synovitis and tenosynovitis, unspecified (Forearm)	0.009	0.991	0.000
M65.9 Synovitis and tenosynovitis, unspecified	0.009	0.991	0.000
M65.95 Synovitis and tenosynovitis, unspecified (Pelvic region and thigh)	0.009	0.991	0.000
M65.92 Synovitis and tenosynovitis, unspecified (Upper arm)	0.008	0.992	0.000
Z04.3 Examination and observation following other accident	0.000	0.992	0.008
C34.2 Middle lobe, bronchus or lung	0.000	0.992	0.008
J39.8 Other specified diseases of upper respiratory tract	0.007	0.993	0.000
M65.90 Synovitis and tenosynovitis, unspecified (Multiple sites)	0.007	0.993	0.000
D35.2 Pituitary gland	0.000	0.993	0.007
M65.98 Synovitis and tenosynovitis, unspecified (Other)	0.007	0.993	0.000
C34 Malignant neoplasm of bronchus and lung	0.000	0.993	0.007
C34.3 Lower lobe, bronchus or lung	0.000	0.993	0.007
T51.9 Alcohol, unspecified	0.006	0.994	0.000
C34.0 Main bronchus	0.000	0.994	0.006
M65.99 Synovitis and tenosynovitis, unspecified (Site unspecified)	0.006	0.994	0.000
D32 Benign neoplasm of meninges	0.000	0.994	0.006
Z04 Examination and observation for other reasons	0.000	0.994	0.006
M65.94 Synovitis and tenosynovitis, unspecified (Hand)	0.006	0.994	0.000
C34.8 Overlapping lesion of bronchus and lung	0.000	0.994	0.006
Z04.9 Examination and observation for unspecified reason	0.000	0.994	0.006
Z04.5 Examination and observation following other inflicted injury	0.000	0.995	0.005
D32.0 Cerebral meninges	0.000	0.995	0.005
Z04.1 Examination and observation following transport accident	0.000	0.995	0.005
H05.8 Other disorders of orbit	0.000	0.995	0.005
Z04.6 General psychiatric examination, requested by authority	0.000	0.995	0.005
D32.1 Spinal meninges	0.000	0.995	0.005
R52.2 Other chronic pain	0.000	0.995	0.005
C34.1 Upper lobe, bronchus or lung	0.000	0.995	0.005
T51 Toxic effect of alcohol	0.005	0.995	0.000
J39.0 Retropharyngeal and parapharyngeal abscess	0.005	0.995	0.000
T51.0 Ethanol	0.004	0.996	0.000
Z04.4 Examination and observation following alleged rape and seduction	0.000	0.996	0.004
Z04.0 Blood-alcohol and blood-drug test	0.000	0.996	0.004
Z04.2 Examination and observation following work accident	0.000	0.996	0.004
M65.97 Synovitis and tenosynovitis, unspecified (Ankle and foot)	0.004	0.996	0.000
J39 Other diseases of upper respiratory tract	0.004	0.996	0.000
H05.2 Exophthalmic conditions	0.000	0.996	0.004
H05 Disorders of orbit	0.000	0.996	0.004
H05.0 Acute inflammation of orbit	0.000	0.996	0.004
O34.2 Maternal care due to uterine scar from previous surgery	0.004	0.996	0.000
T51.8 Other alcohols	0.003	0.996	0.000
T51.3 Fusel oil	0.003	0.996	0.000
T51.2 2-Propanol	0.003	0.996	0.000
T51.1 Methanol	0.003	0.996	0.000
Z09.7 Follow-up examination after combined treatment for other conditions	0.004	0.996	0.000
O86.0 Infection of obstetric surgical wound	0.004	0.996	0.000
H05.9 Disorder of orbit, unspecified	0.000	0.997	0.003
H06.2 Dysthyroid exophthalmos	0.000	0.997	0.003
H05.1 Chronic inflammatory disorders of orbit	0.000	0.997	0.003
J39.3 Upper respiratory tract hypersensitivity reaction, site unspecified	0.003	0.997	0.000
D11.0 Parotid gland	0.003	0.997	0.000
J39.9 Disease of upper respiratory tract, unspecified	0.003	0.997	0.000
C34.9 Bronchus or lung, unspecified	0.000	0.997	0.003
H05.5 Retained (old) foreign body following penetrating wound of orbit	0.000	0.997	0.003
H05.3 Deformity of orbit	0.000	0.997	0.003
H55 Nystagmus and other irregular eye movements	0.003	0.997	0.000
J39.1 Other abscess of pharynx	0.003	0.997	0.000
T82.1 Mechanical complication of cardiac electronic device	0.000	0.997	0.003
S82 Fracture of lower leg, including ankle	0.003	0.997	0.000
T14.0 Superficial injury of unspecified body region	0.000	0.997	0.003
T14.1 Open wound of unspecified body region	0.000	0.997	0.003
O86 Other puerperal infections	0.003	0.997	0.000
T14 Injury of unspecified body region	0.000	0.997	0.003
W07.0 Home	0.003	0.997	0.000
O86.1 Other infection of genital tract following delivery	0.003	0.997	0.000
W07.9 Unspecified place	0.003	0.997	0.000
L53.9 Erythematous condition, unspecified	0.000	0.997	0.003
K74.6 Other and unspecified cirrhosis of liver	0.003	0.997	0.000
S82.9 Fracture of lower leg, part unspecified	0.003	0.997	0.000
K46.9 Unspecified abdominal hernia without obstruction or gangrene	0.003	0.997	0.000
N76.4 Abscess of vulva	0.000	0.997	0.003
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency	0.000	0.997	0.003
Z50.2 Alcohol rehabilitation	0.003	0.997	0.000
M65.96 Synovitis and tenosynovitis, unspecified (Lower leg)	0.003	0.997	0.000
J11.1 Influenza with other respiratory manifestations, virus not identified	0.003	0.997	0.000
Y79.2 Prosthetic and other implants, materials and accessory devices	0.003	0.997	0.000
R17 Unspecified jaundice	0.003	0.997	0.000
D35.0 Adrenal gland	0.000	0.997	0.003
O86.4 Pyrexia of unknown origin following delivery	0.002	0.997	0.000
E05.0 Thyrotoxicosis with diffuse goitre	0.000	0.997	0.003
K91.4 Colostomy and enterostomy malfunction	0.003	0.997	0.000
O86.8 Other specified puerperal infections	0.002	0.997	0.000
S82.5 Fracture of medial malleolus	0.002	0.997	0.000
I84.7 Unspecified thrombosed haemorrhoids	0.000	0.997	0.003
T14.9 Injury, unspecified	0.000	0.997	0.002
D11.9 Major salivary gland, unspecified	0.002	0.998	0.000
H05.4 Enophthalmos	0.000	0.998	0.002
D11 Benign neoplasm of major salivary glands	0.002	0.998	0.000
D35 Benign neoplasm of other and unspecified endocrine glands	0.000	0.998	0.002
S82.90 Fracture of lower leg, part unspecified (closed)	0.002	0.998	0.000
S82.7 Multiple fractures of lower leg	0.002	0.998	0.000
D11.7 Other major salivary glands	0.002	0.998	0.000
R52.9 Pain, unspecified	0.000	0.998	0.002
T14.4 Injury of nerve(s) of unspecified body region	0.000	0.998	0.002
O86.3 Other genito-urinary tract infections following delivery	0.002	0.998	0.000
T14.2 Fracture of unspecified body region	0.000	0.998	0.002
T14.8 Other injuries of unspecified body region	0.000	0.998	0.002
T14.7 Crushing injury and traumatic amputation of unspecified body region	0.000	0.998	0.002
T14.6 Injury of tendons and muscles of unspecified body region	0.000	0.998	0.002
T14.5 Injury of blood vessel(s) of unspecified body region	0.000	0.998	0.002
T14.3 Dislocation, sprain and strain of unspecified body region	0.000	0.998	0.002
J39.2 Other diseases of pharynx	0.002	0.998	0.000
N76.6 Ulceration of vulva	0.000	0.998	0.002
W07 Fall involving chair	0.002	0.998	0.000
Z00.0 General medical examination	0.002	0.998	0.000
T83.5 Infection and inflammatory reaction due to prosthetic device, implant and graft in urinary system	0.002	0.998	0.000
L27.0 Generalised skin eruption due to drugs and medicaments	0.000	0.998	0.002
M19.97 Arthrosis, unspecified (Ankle and foot)	0.002	0.998	0.000
O86.2 Urinary tract infection following delivery	0.002	0.998	0.000
S82.51 Fracture of medial malleolus (open)	0.002	0.998	0.000
S82.91 Fracture of lower leg, part unspecified (open)	0.002	0.998	0.000
M65 Synovitis and tenosynovitis	0.002	0.998	0.000
R52 Pain, not elsewhere classified	0.000	0.998	0.002
X49.9 Unspecified place	0.000	0.998	0.002
T09.0 Superficial injury of trunk, level unspecified	0.000	0.998	0.002
D35.9 Endocrine gland, unspecified	0.000	0.998	0.002
D35.8 Pluriglandular involvement	0.000	0.998	0.002
D35.7 Other specified endocrine glands	0.000	0.998	0.002
D35.6 Aortic body and other paraganglia	0.000	0.998	0.002
D35.5 Carotid body	0.000	0.998	0.002
D35.4 Pineal gland	0.000	0.998	0.002
D35.3 Craniopharyngeal duct	0.000	0.998	0.002
K22.9 Disease of oesophagus, unspecified	0.000	0.998	0.002
W07.8 Other specified place	0.002	0.998	0.000
N76 Other inflammation of vagina and vulva	0.000	0.998	0.002
N76.0 Acute vaginitis	0.000	0.998	0.002
S82.71 Multiple fractures of lower leg (open)	0.002	0.998	0.000
T88.6 Anaphylactic shock due to adverse effect of correct drug or medicament properly administered	0.002	0.998	0.000
T14.21 Fracture of unspecified body region (open)	0.000	0.998	0.002
T14.20 Fracture of unspecified body region (closed)	0.000	0.998	0.002
G24.9 Dystonia, unspecified	0.000	0.998	0.002
W07.2 School, other institution and public administrative area	0.002	0.998	0.000
W07.7 Farm	0.002	0.998	0.000
W07.6 Industrial and construction area	0.002	0.998	0.000
W07.4 Street and highway	0.002	0.998	0.000
W07.3 Sports and athletics area	0.002	0.998	0.000
T09 Other injuries of spine and trunk, level unspecified	0.000	0.998	0.002
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.000	0.998	0.002
M65.44 Radial styloid tenosynovitis [de Quervain] (Hand)	0.002	0.998	0.000
I25.4 Coronary artery aneurysm	0.002	0.998	0.000
N76.5 Ulceration of vagina	0.000	0.998	0.002
O81.4 Vacuum extractor delivery	0.000	0.998	0.002
D69.3 Idiopathic thrombocytopenic purpura	0.002	0.998	0.000
W07.5 Trade and service area	0.002	0.998	0.000
S82.50 Fracture of medial malleolus (closed)	0.002	0.998	0.000
L60.9 Nail disorder, unspecified	0.002	0.998	0.000
W13.9 Unspecified place	0.002	0.998	0.000
I21.4 Acute subendocardial myocardial infarction	0.002	0.998	0.000
M65.0 Abscess of tendon sheath	0.002	0.998	0.000
S82.1 Fracture of upper end of tibia	0.002	0.998	0.000
J11 Influenza, virus not identified	0.002	0.998	0.000
C43.7 Malignant melanoma of lower limb, including hip	0.000	0.998	0.002
J11.8 Influenza with other manifestations, virus not identified	0.002	0.998	0.000
M65.4 Radial styloid tenosynovitis [de Quervain]	0.002	0.998	0.000
T13 Other injuries of lower limb, level unspecified	0.000	0.998	0.002
S52.70 Multiple fractures of forearm (closed)	0.002	0.998	0.000
S82.70 Multiple fractures of lower leg (closed)	0.002	0.998	0.000
J11.0 Influenza with pneumonia, virus not identified	0.002	0.998	0.000
T13.0 Superficial injury of lower limb, level unspecified	0.000	0.998	0.002
W07.1 Residential institution	0.002	0.998	0.000
S82.11 Fracture of upper end of tibia (open)	0.002	0.998	0.000
C50.3 Lower-inner quadrant of breast	0.002	0.998	0.000
M65.2 Calcific tendinitis	0.002	0.998	0.000
R52.0 Acute pain	0.000	0.998	0.002
T09.9 Unspecified injury of trunk, level unspecified	0.000	0.998	0.002
M41.96 Scoliosis, unspecified (Lumbar region)	0.000	0.998	0.002
S52.50 Fracture of lower end of radius (closed)	0.002	0.998	0.000
N76.3 Subacute and chronic vulvitis	0.000	0.998	0.002
S82.4 Fracture of fibula alone	0.002	0.998	0.000
Y57.9 Drug or medicament, unspecified	0.000	0.998	0.002
G93.4 Encephalopathy, unspecified	0.000	0.998	0.002
K35.9 Acute appendicitis, unspecified	0.002	0.998	0.000
D25.1 Intramural leiomyoma of uterus	0.002	0.998	0.000
I80.1 Phlebitis and thrombophlebitis of femoral vein	0.002	0.998	0.000
Q51.8 Other congenital malformations of uterus and cervix	0.000	0.998	0.002
M65.1 Other infective (teno)synovitis	0.002	0.998	0.000
N76.1 Subacute and chronic vaginitis	0.000	0.998	0.002
Q65.8 Other congenital deformities of hip	0.000	0.998	0.002
Z90.2 Acquired absence of lung [part of]	0.000	0.998	0.002
S32.50 Fracture of pubis (closed)	0.002	0.998	0.000
W07.29 Fall involving chair; School, other institution and public administrative area; During unspecified activity	0.001	0.998	0.000
L60.8 Other nail disorders	0.002	0.998	0.000
S56.1 Injury of flexor muscle and tendon of other finger(s) at forearm level	0.002	0.998	0.000
T09.8 Other specified injuries of trunk, level unspecified	0.000	0.998	0.001
T09.6 Traumatic amputation of trunk, level unspecified	0.000	0.998	0.001
T09.5 Injury of unspecified muscle and tendon of trunk	0.000	0.998	0.001
T09.4 Injury of unspecified nerve, spinal nerve root and plexus of trunk	0.000	0.998	0.001
T09.1 Open wound of trunk, level unspecified	0.000	0.998	0.001
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere	0.000	0.998	0.002
T12.X1 Fracture of lower limb, level unspecified (open)	0.000	0.998	0.001
T12.X0 Fracture of lower limb, level unspecified (closed)	0.000	0.998	0.001
T12 Fracture of lower limb, level unspecified	0.000	0.998	0.001
T10.X1 Fracture of upper limb, level unspecified (open)	0.000	0.998	0.001
T10.X0 Fracture of upper limb, level unspecified (closed)	0.000	0.998	0.001
T10 Fracture of upper limb, level unspecified	0.000	0.998	0.001
T08.X1 Fracture of spine, level unspecified (open)	0.000	0.998	0.001
T08.X0 Fracture of spine, level unspecified (closed)	0.000	0.998	0.001
T08 Fracture of spine, level unspecified	0.000	0.998	0.002
M65.04 Abscess of tendon sheath (Hand)	0.001	0.998	0.000
J93.8 Other pneumothorax	0.002	0.998	0.000
S52.5 Fracture of lower end of radius	0.002	0.998	0.000
T09.3 Injury of spinal cord, level unspecified	0.000	0.998	0.001
M65.09 Abscess of tendon sheath (Site unspecified)	0.001	0.998	0.000
M65.08 Abscess of tendon sheath (Other)	0.001	0.998	0.000
M65.07 Abscess of tendon sheath (Ankle and foot)	0.001	0.998	0.000
M65.06 Abscess of tendon sheath (Lower leg)	0.001	0.998	0.000
M65.05 Abscess of tendon sheath (Pelvic region and thigh)	0.001	0.998	0.000
M65.03 Abscess of tendon sheath (Forearm)	0.001	0.998	0.000
M65.02 Abscess of tendon sheath (Upper arm)	0.001	0.998	0.000
M65.01 Abscess of tendon sheath (Shoulder region)	0.001	0.998	0.000
M65.00 Abscess of tendon sheath (Multiple sites)	0.001	0.998	0.000
M65.49 Radial styloid tenosynovitis [de Quervain]-Site unspec	0.001	0.998	0.000
M65.48 Radial styloid tenosynovitis [de Quervain]-Other	0.001	0.998	0.000
M65.47 Radial styloid tenosynovitis [de Quervain]-Ankle/foot	0.001	0.998	0.000
M65.46 Radial styloid tenosynovitis [de Quervain]-Lower leg	0.001	0.998	0.000
M65.45 Radial styloid tenosynovitis [de Quervain]-Pelvic/thigh	0.001	0.998	0.000
M65.42 Radial styloid tenosynovitis [de Quervain]-Upper arm	0.001	0.998	0.000
M65.41 Radial styloid tenosynovitis [de Quervain]-Shldr region	0.001	0.998	0.000
M65.40 Radial styloid tenosynovitis [de Quervain] (Multiple sites)	0.001	0.998	0.000
M90.75 Fracture of bone in neoplastic disease (Pelvic region and thigh)	0.000	0.998	0.002
S52.51 Fracture of lower end of radius (open)	0.002	0.998	0.000
S82.0 Fracture of patella	0.002	0.998	0.000
T13.9 Unspecified injury of lower limb, level unspecified	0.000	0.998	0.001
T79.7 Traumatic subcutaneous emphysema	0.002	0.998	0.000
S52.80 Fracture of other parts of forearm (closed)	0.002	0.998	0.000
J93.0 Spontaneous tension pneumothorax	0.002	0.998	0.000
M20.3 Other deformity of hallux (acquired)	0.002	0.998	0.000
M67.2 Synovial hypertrophy, not elsewhere classified	0.002	0.998	0.000
M92.6 Juvenile osteochondrosis of tarsus	0.000	0.998	0.002
S96.8 Injury of other muscles and tendons at ankle and foot level	0.002	0.998	0.000
T13.8 Other specified injuries of lower limb, level unspecified	0.000	0.998	0.001
T13.6 Traumatic amputation of lower limb, level unspecified	0.000	0.998	0.001
T13.5 Injury of unspecified muscle and tendon of lower limb, level unspecified	0.000	0.998	0.001
T13.4 Injury of unspecified blood vessel of lower limb, level unspecified	0.000	0.998	0.001
T13.3 Injury of unspecified nerve of lower limb, level unspecified	0.000	0.998	0.001
T13.2 Dislocation, strain and sprain of unspecified joint and ligament of lower limb, level unspecified	0.000	0.998	0.001
M65.29 Calcific tendinitis (Site unspecified)	0.001	0.998	0.000
M65.28 Calcific tendinitis (Other)	0.001	0.998	0.000
M65.27 Calcific tendinitis (Ankle and foot)	0.001	0.998	0.000
M65.26 Calcific tendinitis (Lower leg)	0.001	0.998	0.000
M65.25 Calcific tendinitis (Pelvic region and thigh)	0.001	0.998	0.000
M65.24 Calcific tendinitis (Hand)	0.001	0.998	0.000
M65.23 Calcific tendinitis (Forearm)	0.001	0.998	0.000
M65.22 Calcific tendinitis (Upper arm)	0.001	0.998	0.000
M65.20 Calcific tendinitis (Multiple sites)	0.001	0.998	0.000
Q60.0 Renal agenesis, unilateral	0.000	0.998	0.002
Z89.5 Acquired absence of leg at or below knee	0.002	0.998	0.000
H33 Retinal detachments and breaks	0.002	0.998	0.000
M85.00 Fibrous dysplasia (monostotic) (Multiple sites)	0.002	0.998	0.000
B08.1 Molluscum contagiosum	0.002	0.998	0.000
H33.4 Traction detachment of retina	0.002	0.998	0.000
S52.7 Multiple fractures of forearm	0.002	0.998	0.000
S55.1 Injury of radial artery at forearm level	0.002	0.998	0.000
M41.94 Scoliosis, unspecified (Thoracic region)	0.000	0.998	0.002
M65.21 Calcific tendinitis (Shoulder region)	0.001	0.998	0.000
T13.1 Open wound of lower limb, level unspecified	0.000	0.998	0.001
T11 Other injuries of upper limb, level unspecified	0.000	0.998	0.001
T09.2 Dislocation, strain and sprain of unspecified joint and ligament of trunk	0.000	0.998	0.001
T92.8 Sequelae of other specified injuries of upper limb	0.000	0.998	0.002
L60.3 Nail dystrophy	0.002	0.998	0.000
S82.41 Fracture of fibula alone (open)	0.001	0.998	0.000
H54.0 Blindness, both eyes	0.000	0.998	0.002
T18.1 Foreign body in oesophagus	0.002	0.998	0.000
T82.5 Mechanical complication of other cardiac and vascular devices and implants	0.000	0.998	0.002
M65.19 Other infective (teno)synovitis (Site unspecified)	0.001	0.998	0.000
M65.18 Other infective (teno)synovitis (Other)	0.001	0.998	0.000
M65.17 Other infective (teno)synovitis (Ankle and foot)	0.001	0.998	0.000
M65.16 Other infective (teno)synovitis (Lower leg)	0.001	0.998	0.000
M65.15 Other infective (teno)synovitis (Pelvic region and thigh)	0.001	0.998	0.000
M65.13 Other infective (teno)synovitis (Forearm)	0.001	0.998	0.000
M65.12 Other infective (teno)synovitis (Upper arm)	0.001	0.998	0.000
M65.11 Other infective (teno)synovitis (Shoulder region)	0.001	0.998	0.000
M65.10 Other infective (teno)synovitis (Multiple sites)	0.001	0.998	0.000
M90.71 Fracture of bone in neoplastic disease (Shoulder region)	0.000	0.998	0.001
S91.3 Open wound of other parts of foot	0.002	0.998	0.000
S96 Injury of muscle and tendon at ankle and foot level	0.001	0.998	0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.001	0.998	0.000
M43.62 Torticollis-Cervical	0.000	0.998	0.001
M81.90 Osteoporosis, unspecified (Multiple sites)	0.000	0.998	0.001
O87.0 Superficial thrombophlebitis in the puerperium	0.001	0.998	0.000
S56.3 Injury of extensor or abductor muscles and tendons of thumb at forearm level	0.001	0.998	0.000
T59.9 Gases, fumes and vapours, unspecified	0.001	0.998	0.000
Y79 Orthopaedic devices associated with adverse incidents	0.001	0.998	0.000
M24.11 Other articular cartilage disorders (Shoulder region)	0.001	0.999	0.000
H06.3 Other disorders of orbit in diseases classified elsewhere	0.000	0.999	0.001
H06.1 Parasitic infestation of orbit in diseases classified elsewhere	0.000	0.999	0.001
H06.0 Disorders of lachrymal system in diseases classified elsewhere	0.000	0.999	0.001
S52.8 Fracture of other parts of forearm	0.001	0.999	0.000
S96.9 Injury of unspecified muscle and tendon at ankle and foot level	0.001	0.999	0.000
R41.2 Retrograde amnesia	0.001	0.999	0.000
T11.0 Superficial injury of upper limb, level unspecified	0.000	0.999	0.001
S56 Injury of muscle and tendon at forearm level	0.001	0.999	0.000
M90.7 Fracture of bone in neoplastic disease	0.000	0.999	0.001
S56.5 Injury of other extensor muscle and tendon at forearm level	0.001	0.999	0.000
S96.0 Injury of muscle and tendon of long flexor muscle of toe at ankle and foot level	0.001	0.999	0.000
S99.9 Unspecified injury of ankle and foot	0.001	0.999	0.000
M90.72 Fracture of bone in neoplastic disease (Upper arm)	0.000	0.999	0.001
L27 Dermatitis due to substances taken internally	0.000	0.999	0.001
O87 Venous complications in the puerperium	0.001	0.999	0.000
Q60.2 Renal agenesis, unspecified	0.000	0.999	0.001
S96.1 Injury of muscle and tendon of long extensor muscle of toe at ankle and foot level	0.001	0.999	0.000
Q51 Congenital malformations of uterus and cervix	0.000	0.999	0.001
M90.78 Fracture of bone in neoplastic disease (Other)	0.000	0.999	0.001
S52.71 Multiple fractures of forearm (open)	0.001	0.999	0.000
Q51.2 Other doubling of uterus	0.000	0.999	0.001
T11.9 Unspecified injury of upper limb, level unspecified	0.000	0.999	0.001
T11.8 Other specified injuries of upper limb, level unspecified	0.000	0.999	0.001
T11.6 Traumatic amputation of upper limb, level unspecified	0.000	0.999	0.001
T11.5 Injury of unspecified muscle and tendon of upper limb, level unspecified	0.000	0.999	0.001
T11.4 Injury of unspecified blood vessel of upper limb, level unspecified	0.000	0.999	0.001
T11.3 Injury of unspecified nerve of upper limb, level unspecified	0.000	0.999	0.001
T11.2 Dislocation, strain and sprain of unspecified joint and ligament of upper limb, level unspecified	0.000	0.999	0.001
T62 Toxic effect of other noxious substances eaten as food	0.001	0.999	0.000
S22.10 Multiple fractures of thoracic spine (closed)	0.000	0.999	0.001
H57.8 Other specified disorders of eye and adnexa	0.000	0.999	0.001
L27.2 Dermatitis due to ingested food	0.000	0.999	0.001
M34.9 Systemic sclerosis, unspecified	0.000	0.999	0.001
S56.7 Injury of multiple muscles and tendons at forearm level	0.001	0.999	0.000
S55 Injury of blood vessels at forearm level	0.001	0.999	0.000
C30.0 Nasal cavity	0.000	0.999	0.001
G93.3 Postviral fatigue syndrome	0.000	0.999	0.001
I67.9 Cerebrovascular disease, unspecified	0.000	0.999	0.001
M33.2 Polymyositis	0.001	0.999	0.000
N42.1 Congestion and haemorrhage of prostate	0.001	0.999	0.000
O87.8 Other venous complications in the puerperium	0.001	0.999	0.000
S59.9 Unspecified injury of forearm	0.001	0.999	0.000
S82.6 Fracture of lateral malleolus	0.001	0.999	0.000
Y79.3 Surgical instruments, materials and devices (including sutures)	0.001	0.999	0.000
L53 Other erythematous conditions	0.000	0.999	0.001
N76.8 Other specified inflammation of vagina and vulva	0.000	0.999	0.001
S96.7 Injury of multiple muscles and tendons at ankle and foot level	0.001	0.999	0.000
S96.2 Injury of intrinsic muscle and tendon at ankle and foot level	0.001	0.999	0.000
Y79.8 Miscellaneous devices, not elsewhere classified	0.001	0.999	0.000
Y79.1 Therapeutic (nonsurgical) and rehabilitative devices	0.001	0.999	0.000
Y79.0 Diagnostic and monitoring devices	0.001	0.999	0.000
T61 Toxic effect of noxious substances eaten as seafood	0.001	0.999	0.000
T60 Toxic effect of pesticides	0.001	0.999	0.000
T57 Toxic effect of other inorganic substances	0.001	0.999	0.000
T53 Toxic effect of halogen derivatives of aliphatic and aromatic hydrocarbone	0.001	0.999	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations